BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_3251 (186 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HGX5|B2HGX5_MYCMM Tax_Id=216594 (cobU)SubName: Full=Bifunct... 349 9e-95 tr|A0PTP1|A0PTP1_MYCUA Tax_Id=362242 (cobU)SubName: Full=Bifunct... 347 4e-94 tr|Q73YK8|Q73YK8_MYCPA Tax_Id=1770 (cobU)SubName: Full=CobU;[Myc... 243 7e-63 tr|A0QF00|A0QF00_MYCA1 Tax_Id=243243 (cobU)SubName: Full=Cobinam... 241 2e-62 tr|Q1B6S3|Q1B6S3_MYCSS Tax_Id=164756 SubName: Full=Adenosylcobin... 202 1e-50 tr|A1UIA2|A1UIA2_MYCSK Tax_Id=189918 SubName: Full=Adenosylcobin... 202 1e-50 tr|A3Q1R6|A3Q1R6_MYCSJ Tax_Id=164757 SubName: Full=Adenosylcobin... 202 2e-50 tr|A0R063|A0R063_MYCS2 Tax_Id=246196 (cobU)SubName: Full=Cobinam... 186 1e-45 tr|B1MNY5|B1MNY5_MYCA9 Tax_Id=561007 SubName: Full=Putative cobi... 182 1e-44 tr|C1A131|C1A131_RHOE4 Tax_Id=234621 (cobP)SubName: Full=Adenosy... 172 2e-41 tr|C3JJA8|C3JJA8_RHOER Tax_Id=596309 (cobU)SubName: Full=Cobinam... 167 7e-40 tr|C1AUB0|C1AUB0_RHOOB Tax_Id=632772 (cobP)SubName: Full=Adenosy... 162 1e-38 tr|Q0SHL5|Q0SHL5_RHOSR Tax_Id=101510 (cobU)SubName: Full=Bifunct... 157 4e-37 tr|D0LAY1|D0LAY1_GORB4 Tax_Id=526226 SubName: Full=Nicotinate-nu... 154 3e-36 tr|Q5YZ44|Q5YZ44_NOCFA Tax_Id=37329 (cobU)SubName: Full=Putative... 152 2e-35 tr|Q82AM5|Q82AM5_STRAW Tax_Id=33903 (cobU)SubName: Full=Putative... 145 3e-33 tr|C4E9N1|C4E9N1_STRRS Tax_Id=479432 SubName: Full=Adenosyl cobi... 145 3e-33 tr|Q8NNJ9|Q8NNJ9_CORGL Tax_Id=1718 (cobU)SubName: Full=Adenosyl ... 142 1e-32 tr|A4QFR4|A4QFR4_CORGB Tax_Id=340322 SubName: Full=Putative unch... 140 9e-32 tr|A1T227|A1T227_MYCVP Tax_Id=350058 SubName: Full=Adenosylcobin... 138 2e-31 tr|Q9S2R3|Q9S2R3_STRCO Tax_Id=1902 SubName: Full=Putative adenos... 137 6e-31 tr|Q8FNQ3|Q8FNQ3_COREF Tax_Id=152794 SubName: Full=Putative cobi... 137 6e-31 tr|C9YTS5|C9YTS5_STRSW Tax_Id=680198 (cobU)SubName: Full=Putativ... 135 2e-30 tr|A4FA95|A4FA95_SACEN Tax_Id=405948 (cobU)SubName: Full=Cobinam... 134 4e-30 tr|A4T0S0|A4T0S0_MYCGI Tax_Id=350054 SubName: Full=Adenosylcobin... 134 5e-30 tr|A3TS67|A3TS67_9MICO Tax_Id=313589 SubName: Full=Probable bifu... 134 6e-30 tr|B4V3L6|B4V3L6_9ACTO Tax_Id=465541 SubName: Full=Adenosylcobin... 132 1e-29 tr|C2ASV1|C2ASV1_TSUPA Tax_Id=521096 SubName: Full=Nicotinate-nu... 132 2e-29 tr|Q6NG94|Q6NG94_CORDI Tax_Id=1717 (cobU)SubName: Full=Putative ... 132 2e-29 tr|B5I256|B5I256_9ACTO Tax_Id=463191 SubName: Full=Adenosylcobin... 132 2e-29 tr|Q7U2G0|Q7U2G0_MYCBO Tax_Id=1765 (cobU)SubName: Full=PUTATIVE ... 131 4e-29 tr|O53676|O53676_MYCTU Tax_Id=1773 (cobU)SubName: Full=Cobinamid... 131 4e-29 tr|C6DRR1|C6DRR1_MYCTK Tax_Id=478434 SubName: Full=Bifunctional ... 131 4e-29 tr|C1AJT0|C1AJT0_MYCBT Tax_Id=561275 (cobU)SubName: Full=Putativ... 131 4e-29 tr|A5TYY0|A5TYY0_MYCTA Tax_Id=419947 (cobU)SubName: Full=Cobinam... 131 4e-29 tr|A1KF75|A1KF75_MYCBP Tax_Id=410289 (cobU)SubName: Full=Putativ... 131 4e-29 tr|A5WIW1|A5WIW1_MYCTF Tax_Id=336982 SubName: Full=Bifunctional ... 131 4e-29 tr|A2VNG9|A2VNG9_MYCTU Tax_Id=348776 SubName: Full=Bifunctional ... 131 4e-29 tr|B1VZP0|B1VZP0_STRGG Tax_Id=455632 SubName: Full=Putative aden... 130 5e-29 tr|C4RMI1|C4RMI1_9ACTO Tax_Id=219305 SubName: Full=Cobalbumin bi... 130 7e-29 tr|A4KNS2|A4KNS2_MYCTU Tax_Id=395095 SubName: Full=Bifunctional ... 130 7e-29 tr|C8NQ52|C8NQ52_COREF Tax_Id=196164 (cobU)SubName: Full=Cobinam... 129 2e-28 tr|C6W9E8|C6W9E8_ACTMD Tax_Id=446462 SubName: Full=Cobalbumin bi... 126 1e-27 tr|B5GV02|B5GV02_STRCL Tax_Id=443255 SubName: Full=Bifunctional ... 125 2e-27 tr|C7MXA5|C7MXA5_SACVD Tax_Id=471857 SubName: Full=Adenosylcobin... 125 3e-27 tr|C9NGG5|C9NGG5_9ACTO Tax_Id=591167 SubName: Full=Cobalbumin bi... 124 4e-27 tr|D1A8Z3|D1A8Z3_THECU Tax_Id=471852 SubName: Full=Cobalbumin bi... 124 6e-27 tr|C5VDB9|C5VDB9_9CORY Tax_Id=553207 (cobU)SubName: Full=Cobinam... 124 6e-27 tr|C0E4I5|C0E4I5_9CORY Tax_Id=566549 SubName: Full=Putative unch... 122 1e-26 tr|A1SJM9|A1SJM9_NOCSJ Tax_Id=196162 SubName: Full=Adenosylcobin... 121 3e-26 >tr|B2HGX5|B2HGX5_MYCMM Tax_Id=216594 (cobU)SubName: Full=Bifunctional cobalamin biosynthesis protein CobU;[Mycobacterium marinum] Length = 186 Score = 349 bits (895), Expect = 9e-95 Identities = 175/186 (94%), Positives = 175/186 (94%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGP WDQRVARHRDR Sbjct: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPATDSDSAASQDWDQRVARHRDR 60 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM Sbjct: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP Sbjct: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 Query: 181 IKPSRA 186 IKPSRA Sbjct: 181 IKPSRA 186 >tr|A0PTP1|A0PTP1_MYCUA Tax_Id=362242 (cobU)SubName: Full=Bifunctional cobalamin biosynthesis protein CobU;[Mycobacterium ulcerans] Length = 186 Score = 347 bits (890), Expect = 4e-94 Identities = 174/186 (93%), Positives = 174/186 (93%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGP WDQRVARHRDR Sbjct: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPATDSDSAASQDWDQRVARHRDR 60 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RPGHWSTVETDDI TQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM Sbjct: 61 RPGHWSTVETDDIATQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP Sbjct: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 Query: 181 IKPSRA 186 IKPSRA Sbjct: 181 IKPSRA 186 >tr|Q73YK8|Q73YK8_MYCPA Tax_Id=1770 (cobU)SubName: Full=CobU;[Mycobacterium paratuberculosis] Length = 178 Score = 243 bits (620), Expect = 7e-63 Identities = 124/182 (68%), Positives = 137/182 (75%), Gaps = 8/182 (4%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGGIRSGKS+WAE+ +AD L +PVRYLA GP W RVA HRDR Sbjct: 1 MRTLVLGGIRSGKSQWAEDAVADGLPAGRPVRYLAPGPPGAHDAA----WAHRVAEHRDR 56 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP HWST+ETDDI T+LR+ P PTLVDDLG WLT +D H W+GGS A +DD+ Sbjct: 57 RPAHWSTIETDDIATELRRCPQVPTLVDDLGGWLTGMLDRHDGWQGGSVTAP----VDDV 112 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 LAAV EF LVLVSPEVGLTVVPATAS RRFADELG+LNQR+A LCDRVVLVVAGQ VP Sbjct: 113 LAAVAEFAGALVLVSPEVGLTVVPATASARRFADELGSLNQRLARLCDRVVLVVAGQPVP 172 Query: 181 IK 182 IK Sbjct: 173 IK 174 >tr|A0QF00|A0QF00_MYCA1 Tax_Id=243243 (cobU)SubName: Full=Cobinamide kinase / cobinamide phosphate guanyltransferase; EC=2.7.1.156; EC=2.7.7.62;[Mycobacterium avium] Length = 178 Score = 241 bits (616), Expect = 2e-62 Identities = 124/182 (68%), Positives = 137/182 (75%), Gaps = 8/182 (4%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGGIRSGKS+WAEE +AD L + VRYLA GP W RVA HRDR Sbjct: 1 MRTLVLGGIRSGKSQWAEEAVADGLPAGRRVRYLAPGPPGVHDAA----WAHRVAEHRDR 56 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP HWST+ETDDI T+LR+ P PTLVDDLG WLT +D H W+GGS A +DD+ Sbjct: 57 RPAHWSTIETDDIATELRRCPQVPTLVDDLGGWLTGMLDRHDGWQGGSVTAP----VDDL 112 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 LAAV EF + LVLVSPEVGLTVVPATAS RRFADELG+LNQR+A LCDRVVLVVAGQ VP Sbjct: 113 LAAVAEFAAALVLVSPEVGLTVVPATASARRFADELGSLNQRLARLCDRVVLVVAGQPVP 172 Query: 181 IK 182 IK Sbjct: 173 IK 174 >tr|Q1B6S3|Q1B6S3_MYCSS Tax_Id=164756 SubName: Full=Adenosylcobinamide kinase; EC=2.7.1.156;[Mycobacterium sp.] Length = 176 Score = 202 bits (514), Expect = 1e-50 Identities = 110/182 (60%), Positives = 128/182 (70%), Gaps = 9/182 (4%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGGIRSGKSRWAE IA + P+ PVRY+A+G W +RVA HR R Sbjct: 1 MRTLVLGGIRSGKSRWAEAVIAAAAQPD-PVRYVATGASPGADDE----WARRVAAHRRR 55 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP W T ET D+ LR P T TLVDD+G WLT+ MD AW GGS A D + Sbjct: 56 RPSGWRTTETTDVPGALRDDPATATLVDDIGGWLTAEMDRCDAWHGGSVAAGA----DAL 111 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 +AAV EF ++LVLVSPEVGLTVVPATA+GRRFADELG LNQR+AA C+RVVL+VAGQ + Sbjct: 112 VAAVAEFTASLVLVSPEVGLTVVPATAAGRRFADELGALNQRLAATCERVVLIVAGQPIT 171 Query: 181 IK 182 +K Sbjct: 172 VK 173 >tr|A1UIA2|A1UIA2_MYCSK Tax_Id=189918 SubName: Full=Adenosylcobinamide kinase; EC=2.7.1.156;[Mycobacterium sp.] Length = 176 Score = 202 bits (514), Expect = 1e-50 Identities = 110/182 (60%), Positives = 128/182 (70%), Gaps = 9/182 (4%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGGIRSGKSRWAE IA + P+ PVRY+A+G W +RVA HR R Sbjct: 1 MRTLVLGGIRSGKSRWAEAVIAAAAQPD-PVRYVATGASPGADDE----WARRVAAHRRR 55 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP W T ET D+ LR P T TLVDD+G WLT+ MD AW GGS A D + Sbjct: 56 RPSGWRTTETTDVPGALRDDPATATLVDDIGGWLTAEMDRCDAWHGGSVAAGA----DAL 111 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 +AAV EF ++LVLVSPEVGLTVVPATA+GRRFADELG LNQR+AA C+RVVL+VAGQ + Sbjct: 112 VAAVAEFTASLVLVSPEVGLTVVPATAAGRRFADELGALNQRLAATCERVVLIVAGQPIT 171 Query: 181 IK 182 +K Sbjct: 172 VK 173 >tr|A3Q1R6|A3Q1R6_MYCSJ Tax_Id=164757 SubName: Full=Adenosylcobinamide kinase; EC=2.7.1.156;[Mycobacterium sp.] Length = 176 Score = 202 bits (513), Expect = 2e-50 Identities = 110/182 (60%), Positives = 128/182 (70%), Gaps = 9/182 (4%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGGIRSGKSRWAE IA + P+ PVRY+A+G W +RVA HR R Sbjct: 1 MRTLVLGGIRSGKSRWAEAVIAAAAQPD-PVRYVATGASPGADDE----WARRVAAHRRR 55 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP W T ET D+ LR P T TLVDD+G WLT+ MD AW GGS A D + Sbjct: 56 RPSGWRTTETTDVPGALRDDPATATLVDDVGGWLTAEMDRCDAWHGGSVAAGA----DAL 111 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 +AAV EF ++LVLVSPEVGLTVVPATA+GRRFADELG LNQR+AA C+RVVL+VAGQ + Sbjct: 112 VAAVAEFTASLVLVSPEVGLTVVPATAAGRRFADELGALNQRLAATCERVVLIVAGQPIT 171 Query: 181 IK 182 +K Sbjct: 172 VK 173 >tr|A0R063|A0R063_MYCS2 Tax_Id=246196 (cobU)SubName: Full=Cobinamide kinase / cobinamide phosphate guanyltransferase; EC=2.7.1.156; EC=2.7.7.62;[Mycobacterium smegmatis] Length = 177 Score = 186 bits (472), Expect = 1e-45 Identities = 103/182 (56%), Positives = 121/182 (66%), Gaps = 12/182 (6%) Query: 4 LVLGGIRSGKSRWAEETIADSLTPE---QPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 LVLGGIRSGKS+WAE ++A L E PVRY+A+GP W RV H+ R Sbjct: 2 LVLGGIRSGKSQWAE-SVAQQLAGEGDRAPVRYVATGPVPEGDAD----WATRVEAHQVR 56 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP HW TVET D+T L P TLVDD+G WLT+ MD AW G + +D Sbjct: 57 RPAHWQTVETTDLTATLTAAPHVATLVDDIGGWLTATMDRRDAWAGHPVTGDVTALVD-- 114 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 AV F + LV+VSPEVGLTVVPATA+GRRFADELGT+NQR+AA+CDRVVLVVAGQ V Sbjct: 115 --AVAAFRAPLVMVSPEVGLTVVPATAAGRRFADELGTVNQRLAAVCDRVVLVVAGQPVT 172 Query: 181 IK 182 +K Sbjct: 173 VK 174 >tr|B1MNY5|B1MNY5_MYCA9 Tax_Id=561007 SubName: Full=Putative cobinamide kinase/cobinamide phosphate guanylyltransferase CobU;[Mycobacterium abscessus] Length = 177 Score = 182 bits (462), Expect = 1e-44 Identities = 102/184 (55%), Positives = 123/184 (66%), Gaps = 10/184 (5%) Query: 3 TLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRRP 62 TLVLGGIRSGKSR+AE L E P RYLA+G W +R+A HR RRP Sbjct: 4 TLVLGGIRSGKSRFAESL----LPAEGPARYLATGSPDTGDPA----WTERIAAHRSRRP 55 Query: 63 GHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDMLA 122 W+T ET DI T+LR PTLVDDLG WLT+AMD+H AW+ G+ A+ I ++ Sbjct: 56 SQWTTAETTDIATELRTRAPLPTLVDDLGGWLTAAMDAHGAWDVGA--GAVSADIGALVE 113 Query: 123 AVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVPIK 182 AV ++ LV+VSPEVGLTVVPATA+GR FAD LG LNQ +AA DRV+LVVAGQ + IK Sbjct: 114 AVADYPVDLVIVSPEVGLTVVPATAAGRLFADALGALNQAVAARADRVLLVVAGQPLTIK 173 Query: 183 PSRA 186 R+ Sbjct: 174 GGRS 177 >tr|C1A131|C1A131_RHOE4 Tax_Id=234621 (cobP)SubName: Full=Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; EC=2.7.1.156; EC=2.7.7.62;[Rhodococcus erythropolis] Length = 195 Score = 172 bits (435), Expect = 2e-41 Identities = 95/190 (50%), Positives = 120/190 (63%), Gaps = 11/190 (5%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQ--PVRYLASGPXXXXXXXXXXXWDQRVARHRD 59 RTLVLGG RSGKS AE+ + PE P+RYLA+ W+ R+ +HR+ Sbjct: 6 RTLVLGGARSGKSAHAEDLVCAGHLPESSAPIRYLATA----RRDVTDADWESRIDQHRN 61 Query: 60 RRPGHWSTVET---DDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDT 116 RRP HWSTVET D+ QL T TLVDDLGTWLT+ +D AW+ +P + Sbjct: 62 RRPSHWSTVETAAAGDLAAQLESDSHTATLVDDLGTWLTTELDRQGAWD--APRGTITPA 119 Query: 117 IDDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAG 176 D ++A+V + LVLVSPEVGL V+P T SGR F DE+GTLN R+AA+CDRVVLVVAG Sbjct: 120 ADSLVASVENYRGHLVLVSPEVGLAVIPETRSGRLFRDEIGTLNARIAAVCDRVVLVVAG 179 Query: 177 QAVPIKPSRA 186 + +K + A Sbjct: 180 LPLILKDTAA 189 >tr|C3JJA8|C3JJA8_RHOER Tax_Id=596309 (cobU)SubName: Full=Cobinamide kinase / cobinamide phosphate guanyltransferase; EC=2.7.1.156; EC=2.7.7.62;[Rhodococcus erythropolis SK121] Length = 188 Score = 167 bits (422), Expect = 7e-40 Identities = 92/188 (48%), Positives = 118/188 (62%), Gaps = 11/188 (5%) Query: 4 LVLGGIRSGKSRWAEETIADSLTPEQ--PVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 +VLGG RSGKS AE+ + PE P+RYLA+ W+ R+ +HR+RR Sbjct: 1 MVLGGARSGKSAHAEDLVCAGHLPESSAPIRYLATA----RRDVSDADWESRIDQHRNRR 56 Query: 62 PGHWSTVET---DDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTID 118 P HWSTVET D+ QL T TLVDDLGTWLT+ +D AW+ +P + D Sbjct: 57 PSHWSTVETAAAGDLAAQLESDSHTATLVDDLGTWLTAELDRQGAWD--APRGTVTPAAD 114 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 ++A+V + LVLVSPEVGL V+P T SGR F DE+GTLN R+AA+CDRVVLVVAG Sbjct: 115 SLVASVENYRGHLVLVSPEVGLAVIPETRSGRLFRDEIGTLNARIAAVCDRVVLVVAGLP 174 Query: 179 VPIKPSRA 186 + +K + A Sbjct: 175 LILKDTAA 182 >tr|C1AUB0|C1AUB0_RHOOB Tax_Id=632772 (cobP)SubName: Full=Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; EC=2.7.1.156; EC=2.7.7.62;[Rhodococcus opacus] Length = 214 Score = 162 bits (411), Expect = 1e-38 Identities = 96/189 (50%), Positives = 116/189 (61%), Gaps = 11/189 (5%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG RSGKS AEE + SL VRY+A+ W+ RVA HRDRR Sbjct: 18 RTLVLGGARSGKSAHAEE-LTQSLAGAGRVRYVATSQRDPDDHD----WEHRVAEHRDRR 72 Query: 62 PGHWSTVETD---DITTQLRQVPDTP-TLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTI 117 P W TVET D+ +LR D TLVDDLGTWLT +D AW+ SP + Sbjct: 73 PDSWVTVETAHRRDLADRLRSATDAAATLVDDLGTWLTVELDGAAAWD--SPRGTIGPRT 130 Query: 118 DDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 DD++ AV ++ LVLV+PEVGL V+P T SGR F DE+GTLN R+A +CDRVVLVVAG Sbjct: 131 DDLVGAVRDYRGALVLVTPEVGLGVIPETRSGRLFRDEIGTLNARLAQVCDRVVLVVAGL 190 Query: 178 AVPIKPSRA 186 + +K A Sbjct: 191 TMTLKDDPA 199 >tr|Q0SHL5|Q0SHL5_RHOSR Tax_Id=101510 (cobU)SubName: Full=Bifunctional adenosylcobinamide kinase/ adenosylcobinamide phosphate guanylyltransferase;[Rhodococcus sp.] Length = 215 Score = 157 bits (398), Expect = 4e-37 Identities = 92/189 (48%), Positives = 118/189 (62%), Gaps = 11/189 (5%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG RSGKS AEE + +L VRY+A+ W+ R+A+HRDRR Sbjct: 18 RTLVLGGARSGKSAHAEE-LTQALAGAGRVRYVATS----HRDPDDHDWEHRIAQHRDRR 72 Query: 62 PGHWSTVETD---DITTQLRQVPD-TPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTI 117 P W TVET D+ QLR + + TLVDDLGTWLT +D AW+ SP + Sbjct: 73 PASWLTVETAHRLDLAGQLRSPTEASATLVDDLGTWLTVELDGAAAWD--SPRGTITPRT 130 Query: 118 DDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 D+++A+V ++ LVLV+PEVGL V+P T SGR F DE+G LN R+A +CDRVVLVVAG Sbjct: 131 DELVASVRDYRGALVLVTPEVGLGVIPETRSGRLFRDEIGALNARLAQVCDRVVLVVAGL 190 Query: 178 AVPIKPSRA 186 + +K A Sbjct: 191 TMILKDDPA 199 >tr|D0LAY1|D0LAY1_GORB4 Tax_Id=526226 SubName: Full=Nicotinate-nucleotide/dimethylbenzimidazolephosp horibosyltransferase;[Gordonia bronchialis] Length = 590 Score = 154 bits (390), Expect = 3e-36 Identities = 85/180 (47%), Positives = 110/180 (61%), Gaps = 11/180 (6%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG+RSGKS E +A VRYLA+GP W RV RHR RR Sbjct: 7 RTLVLGGVRSGKSEHGESLLA----AHTQVRYLATGPTTSSDAH----WVARVERHRTRR 58 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDML 121 ++T+ET D+ LR P P LVDDLG WL + +D+ W + P L +DD+ Sbjct: 59 DARYTTIETTDLADSLRAAPAIPALVDDLGNWLAARIDAADGW---TKPLDLSAEVDDVC 115 Query: 122 AAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVPI 181 AA+ E + +VL+SPEVGL+VV T +GR F D+LG LN +AA+CDRVVLVVAG+ + + Sbjct: 116 AALTEMSADVVLISPEVGLSVVAPTPAGRTFQDQLGALNTAIAAVCDRVVLVVAGRVLEL 175 >tr|Q5YZ44|Q5YZ44_NOCFA Tax_Id=37329 (cobU)SubName: Full=Putative cobinamide kinase/cobinamide phosphate guanylyltransferase;[Nocardia farcinica] Length = 176 Score = 152 bits (383), Expect = 2e-35 Identities = 89/183 (48%), Positives = 114/183 (62%), Gaps = 12/183 (6%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG RSGKS +AE +S T VRYLA+ + RVA HR RR Sbjct: 4 RTLVLGGARSGKSAFAERLAGESAT----VRYLATA----VLDPADTDFADRVAGHRARR 55 Query: 62 PGHWSTVETDDITTQLRQVPDTP--TLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDD 119 P HW+TV++ D T L P P TLVDDLGTWLT+ +D+ AW+ +P + D Sbjct: 56 PAHWTTVDSADPATVLTAEPGFPGATLVDDLGTWLTARIDALDAWD--APRGTVAPAADA 113 Query: 120 MLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAV 179 ++AAV ++ LV+VSPEVG+ VVPAT SGR F DE+G LNQ +AA+C+ LVVAG + Sbjct: 114 LVAAVRDYPGRLVIVSPEVGMGVVPATRSGRLFRDEIGALNQALAAVCEEAYLVVAGLPL 173 Query: 180 PIK 182 +K Sbjct: 174 RLK 176 >tr|Q82AM5|Q82AM5_STRAW Tax_Id=33903 (cobU)SubName: Full=Putative adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase;[Streptomyces avermitilis] Length = 439 Score = 145 bits (365), Expect = 3e-33 Identities = 87/185 (47%), Positives = 112/185 (60%), Gaps = 13/185 (7%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG RSGKS AE + V Y+A+G W +RV+ HR+RR Sbjct: 262 RTLVLGGARSGKSVEAERRLESF----PDVLYVATG----GSRGGDTEWAERVSVHRERR 313 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWE----GGSPPAALQDTI 117 PG W TVET D+ L++ P L+D L WLT AMDS AW+ G AL+ + Sbjct: 314 PGSWRTVETCDLVPLLKE-DGPPLLIDCLSLWLTDAMDSVNAWDDDEWAGGGERALRGRV 372 Query: 118 DDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 +++ AAV E G T+V VS EVG +VPATASGRR+ DELG LN AA C+ ++LVVAGQ Sbjct: 373 EELTAAVRETGRTVVAVSNEVGSGIVPATASGRRYRDELGRLNAAFAAECEHLLLVVAGQ 432 Query: 178 AVPIK 182 A+ ++ Sbjct: 433 AMVLR 437 >tr|C4E9N1|C4E9N1_STRRS Tax_Id=479432 SubName: Full=Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase;[Streptosporangium roseum DSM 43021] Length = 386 Score = 145 bits (365), Expect = 3e-33 Identities = 84/180 (46%), Positives = 107/180 (59%), Gaps = 9/180 (5%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTL+LGG RSGKS AE +A E V Y+A+GP W +RV HRDRR Sbjct: 214 RTLLLGGTRSGKSAEAELRLAG----EPEVLYVATGPSGGDDDE----WTRRVQTHRDRR 265 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDML 121 P HW T ET D+ LR + P L+D LGTW+ + D AW GG A+ D+++ Sbjct: 266 PAHWGTAETTDLAGLLRTA-EAPMLIDGLGTWVAAVFDECDAWSGGDGRDAVTARCDELV 324 Query: 122 AAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVPI 181 AA + + +V VS EVGL VVPAT+SGR F D LG LNQR+A + V LVVAG+ +P+ Sbjct: 325 AAWRQARAQVVAVSDEVGLGVVPATSSGRMFRDVLGRLNQRLALESEDVALVVAGRLLPL 384 >tr|Q8NNJ9|Q8NNJ9_CORGL Tax_Id=1718 (cobU)SubName: Full=Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; SubName: Full=COBINAMIDE KINASE / COBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE; EC=2.7.1.-;[Corynebacterium glutamicum] Length = 174 Score = 142 bits (359), Expect = 1e-32 Identities = 86/183 (46%), Positives = 109/183 (59%), Gaps = 12/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGG RSGKS +AE SL PV Y+A+ + +R+A H +R Sbjct: 1 MRTLVLGGARSGKSAFAE-----SLVGSGPVLYVATA----RPSGDDPEFAERIAVHAER 51 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP W E D+ L P P LVDDLGTWLT A D+ WE S A L+ +D + Sbjct: 52 RPTSWVLDEEGDVDKLLASPPAMPVLVDDLGTWLTHATDACDGWEASS--AQLEAKMDLL 109 Query: 121 LAAVGEF-GSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAV 179 + A+ F G LV+VSPEVG+ +VP SGR F D +GTLNQR+AA+C+RVV VVAG + Sbjct: 110 IDAILHFQGEDLVIVSPEVGMGIVPEYKSGRLFRDRIGTLNQRVAAICERVVFVVAGLPL 169 Query: 180 PIK 182 +K Sbjct: 170 ELK 172 >tr|A4QFR4|A4QFR4_CORGB Tax_Id=340322 SubName: Full=Putative uncharacterized protein;[Corynebacterium glutamicum] Length = 174 Score = 140 bits (352), Expect = 9e-32 Identities = 86/183 (46%), Positives = 109/183 (59%), Gaps = 12/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGG RSGKS +AE SL PV Y+A+ + +R+A H R Sbjct: 1 MRTLVLGGARSGKSAFAE-----SLVGCGPVLYVATA----RPSGDDPEFAERIAVHAAR 51 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP W E D+ L P P LVDDLGTWLT A D+ WE S A L+ +D + Sbjct: 52 RPTSWVLDEEGDVDKLLASPPAIPVLVDDLGTWLTHATDACDGWEASS--AQLEAKMDLL 109 Query: 121 LAAVGEF-GSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAV 179 + A+ F G+ LV+VSPEVG+ +VP SGR F D +GTLNQR+AA+C+RVV VVAG + Sbjct: 110 IDAILHFQGADLVIVSPEVGMGIVPEYKSGRLFRDRIGTLNQRVAAICERVVFVVAGLPL 169 Query: 180 PIK 182 +K Sbjct: 170 ELK 172 >tr|A1T227|A1T227_MYCVP Tax_Id=350058 SubName: Full=Adenosylcobinamide kinase; EC=2.7.1.156;[Mycobacterium vanbaalenii] Length = 175 Score = 138 bits (348), Expect = 2e-31 Identities = 85/185 (45%), Positives = 108/185 (58%), Gaps = 14/185 (7%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 M LV GG+RSGKSR AE ++D+ + V YLA G WD RVA HR R Sbjct: 1 MMILVTGGVRSGKSRHAEALLSDA----RQVTYLAPG---RPADGSDPDWDARVAGHRTR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP HW TVET D+ +R D LVD LGTWLT+ +D + W+ GS + D +D Sbjct: 54 RPAHWQTVETADVAAAVRDA-DGAVLVDCLGTWLTAVLDRNNLWDKGS--REVHDAVDAR 110 Query: 121 L----AAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAG 176 L AA+ +V+V+ EVGL VVP+ SG F D LGT NQR+AA+CD V LV+AG Sbjct: 111 LTALCAALTARREAVVVVTNEVGLGVVPSHRSGVLFRDLLGTANQRVAAVCDEVHLVIAG 170 Query: 177 QAVPI 181 + + I Sbjct: 171 RVLKI 175 >tr|Q9S2R3|Q9S2R3_STRCO Tax_Id=1902 SubName: Full=Putative adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase;[Streptomyces coelicolor] Length = 397 Score = 137 bits (345), Expect = 6e-31 Identities = 89/187 (47%), Positives = 108/187 (57%), Gaps = 17/187 (9%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG RSGKS AE L P V Y+A+G W RV HR+RR Sbjct: 221 RTLVLGGARSGKSVEAERR----LEPFPDVLYVATG----GSRNGDTEWAARVGAHRERR 272 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWE------GGSPPAALQD 115 PG W T ET D+ L+ P LVD L WLT AMD+ AW+ GG AL+D Sbjct: 273 PGSWRTAETCDLVPLLKD-EGPPLLVDCLSLWLTDAMDAVGAWDDEEWADGGE--RALRD 329 Query: 116 TIDDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVA 175 + ++ AV TLV VS EVG +VPATASGRR+ DELG LN AA C++V+LVVA Sbjct: 330 RVRELTQAVRGTRRTLVAVSNEVGSGIVPATASGRRYRDELGRLNAAFAAECEQVLLVVA 389 Query: 176 GQAVPIK 182 GQA+ ++ Sbjct: 390 GQALVLR 396 >tr|Q8FNQ3|Q8FNQ3_COREF Tax_Id=152794 SubName: Full=Putative cobinamide kinase/cobinamide phosphate guanylyltransferase;[Corynebacterium efficiens] Length = 176 Score = 137 bits (345), Expect = 6e-31 Identities = 84/186 (45%), Positives = 108/186 (58%), Gaps = 14/186 (7%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGG RSGKS +AEE PV Y+A+ + R+A H R Sbjct: 1 MRTLVLGGARSGKSVFAEEIAGPG-----PVVYVATA----RPWPGDEDFAARIAAHVAR 51 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDS--HRAWEGGSPPAALQDTID 118 RP W+T + D+ T LR+ LVDDLGTWLT D+ AWE P L +D Sbjct: 52 RPAGWTTEDRRDVVTLLREPTSATMLVDDLGTWLTHVTDTCGTPAWEHDHP--GLTAEMD 109 Query: 119 DMLAAVGEF-GSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 ++ AV + G LV+V+PEVG+ V+P SGR F D +GTLNQR+A +C+RVVLVVAG Sbjct: 110 ALVDAVATYSGGNLVIVTPEVGMAVIPEHRSGRLFRDRIGTLNQRLATVCERVVLVVAGL 169 Query: 178 AVPIKP 183 + +KP Sbjct: 170 PLELKP 175 >tr|C9YTS5|C9YTS5_STRSW Tax_Id=680198 (cobU)SubName: Full=Putative cobalamin biosynthesis protein;[Streptomyces scabies] Length = 397 Score = 135 bits (340), Expect = 2e-30 Identities = 85/187 (45%), Positives = 105/187 (56%), Gaps = 16/187 (8%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG RSGKS AE + P+ V Y+A+G W RV HR+RR Sbjct: 220 RTLVLGGARSGKSVEAERRL--EAFPD--VLYVATG----GTRGGDGEWAARVTAHRERR 271 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWE------GGSPPAALQD 115 PG W TVET D+ L+ P L+D L WLT MD AW+ GG AL+ Sbjct: 272 PGSWRTVETCDLVPLLKNDDGAPLLIDCLSLWLTDVMDEVGAWDDAEWADGGE--RALRA 329 Query: 116 TIDDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVA 175 + ++ AV T+V VS EVG +VP TASGRRF DELG LN A C+ V+LVVA Sbjct: 330 RVTELTDAVRNTRRTVVAVSNEVGSGIVPTTASGRRFRDELGRLNASFGAQCEHVLLVVA 389 Query: 176 GQAVPIK 182 GQA+P++ Sbjct: 390 GQALPLR 396 >tr|A4FA95|A4FA95_SACEN Tax_Id=405948 (cobU)SubName: Full=Cobinamide kinase / conamide phosphate guanylyltransferase; EC=2.7.1.156; EC=2.7.7.62;[Saccharopolyspora erythraea] Length = 181 Score = 134 bits (338), Expect = 4e-30 Identities = 86/182 (47%), Positives = 106/182 (58%), Gaps = 17/182 (9%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG RSGKS AE +A++ PV Y+A+ W +R+A H RR Sbjct: 4 RTLVLGGARSGKSAHAEGLLAET----DPVTYVATS----RRDPSDREWTERIAEHVARR 55 Query: 62 PGHWSTVETDD---ITTQLRQVPD-TPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDT- 116 P W TVE D + L + PD +P LVDDL TWLT +D AW+ P AL+ Sbjct: 56 PDTWRTVEAGDPGELRRVLAEPPDGSPLLVDDLATWLTGVLDDAGAWD--RDPDALRRVS 113 Query: 117 --IDDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVV 174 D ++ AV + LVLVS EVGL +VPAT SGR F DELG LN R+A +CD VVL+V Sbjct: 114 ADADALVGAVRTCRARLVLVSAEVGLGIVPATRSGRLFRDELGALNARLAEVCDEVVLLV 173 Query: 175 AG 176 AG Sbjct: 174 AG 175 >tr|A4T0S0|A4T0S0_MYCGI Tax_Id=350054 SubName: Full=Adenosylcobinamide kinase; EC=2.7.1.156;[Mycobacterium gilvum] Length = 174 Score = 134 bits (337), Expect = 5e-30 Identities = 82/184 (44%), Positives = 109/184 (59%), Gaps = 13/184 (7%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKSR AEE +A + V Y+A G WD RV+RHR R Sbjct: 1 MRILVTGGVRSGKSRHAEELLAGA----GHVTYVAPG---RAADGTDPDWDARVSRHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP HW TVET D+ +R T LVD LGTWLT+ +D + W+ GS A D ++ Sbjct: 54 RPAHWRTVETADVAVAVRDAQGT-VLVDCLGTWLTAVLDDNGLWDKGSREAT--DEVEIR 110 Query: 121 LAAVGEF---GSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 + A+ + + V+V+ EVGL VVP+ SG F D LGT+NQR+A +CD V LV+AG+ Sbjct: 111 VTALCDALAGAAGAVVVTNEVGLGVVPSHRSGVLFRDLLGTVNQRVAQVCDEVHLVIAGR 170 Query: 178 AVPI 181 + + Sbjct: 171 VLTL 174 >tr|A3TS67|A3TS67_9MICO Tax_Id=313589 SubName: Full=Probable bifunctional cobalamin biosynthesis protein cobu:cobinamide kinase + cobinamide phosphate;[Janibacter sp. HTCC2649] Length = 186 Score = 134 bits (336), Expect = 6e-30 Identities = 85/189 (44%), Positives = 107/189 (56%), Gaps = 15/189 (7%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSL---TPEQPVRYLASGPXXXXXXXXXXXWDQRVARH 57 MRTLV GG+RSGKS AE+ IAD+ +P PV Y+A+GP W R+A H Sbjct: 4 MRTLVTGGVRSGKSVIAEKFIADAAALHSPGVPVTYVATGPAADDAD-----WADRIATH 58 Query: 58 RDRRPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTI 117 R RRP W TVET D+ + L + P LVD LGTWLT+ +D WE +P QD + Sbjct: 59 RSRRPDTWQTVETHDLASALDALTG-PALVDCLGTWLTAVLDELDVWE--APREGWQDAL 115 Query: 118 D----DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLV 173 D++ A +V V+ EVG VV SGR FADELG LNQ +A DRV LV Sbjct: 116 HKRTADVVRAWARCPHDVVAVTNEVGWGVVSEHRSGRIFADELGRLNQDIARASDRVFLV 175 Query: 174 VAGQAVPIK 182 AG +P++ Sbjct: 176 AAGHLLPLR 184 >tr|B4V3L6|B4V3L6_9ACTO Tax_Id=465541 SubName: Full=Adenosylcobinamide kinase;[Streptomyces sp. Mg1] Length = 197 Score = 132 bits (333), Expect = 1e-29 Identities = 88/185 (47%), Positives = 108/185 (58%), Gaps = 13/185 (7%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG RSGKS AE +A PE V Y+A+G W RV HR+RR Sbjct: 21 RTLVLGGARSGKSYEAERRLAGF--PE--VVYVATG----GSREGDAEWAARVGLHRERR 72 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAA----LQDTI 117 P W TVET ++ L + P LVD L WLT AMD AW+ A L + + Sbjct: 73 PSSWRTVETCELVPLLVE-GGPPLLVDCLALWLTDAMDRAGAWDDAVWAATGRKELAERV 131 Query: 118 DDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 +++AAV T+V VS EVG VVPATASGRRF DELG LN +AA C+ V+LV+AGQ Sbjct: 132 AELVAAVRSTRRTVVAVSNEVGSGVVPATASGRRFRDELGRLNNAVAAECEHVLLVLAGQ 191 Query: 178 AVPIK 182 A+ +K Sbjct: 192 ALVLK 196 >tr|C2ASV1|C2ASV1_TSUPA Tax_Id=521096 SubName: Full=Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase;[Tsukamurella paurometabola DSM 20162] Length = 559 Score = 132 bits (332), Expect = 2e-29 Identities = 82/176 (46%), Positives = 103/176 (58%), Gaps = 10/176 (5%) Query: 4 LVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRRPG 63 LVLGG+RSGKS AE+ I + VRY+A+ P R+ HR RRP Sbjct: 5 LVLGGVRSGKSARAEQLIT-AAAGSAAVRYVATAPRPDGDPDLA----SRIDAHRSRRPQ 59 Query: 64 HWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDMLAA 123 W+TVET D+ L D TLVDDLG WL + +D+ WE PA + D + ++ A Sbjct: 60 SWTTVETQDLAA-LFATGDVATLVDDLGAWLAARLDA-AGWES---PARVDDEVAALVNA 114 Query: 124 VGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAV 179 + LV VSPEVGL+VVPAT +GR F D LG LN R+AA+ D V LVVAG+AV Sbjct: 115 AAAYRGELVFVSPEVGLSVVPATHAGRVFQDLLGDLNARLAAVADGVELVVAGRAV 170 >tr|Q6NG94|Q6NG94_CORDI Tax_Id=1717 (cobU)SubName: Full=Putative cobinamide kinase;[Corynebacterium diphtheriae] Length = 182 Score = 132 bits (331), Expect = 2e-29 Identities = 76/187 (40%), Positives = 111/187 (59%), Gaps = 13/187 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 M TLVLGG RSGKS +AE+ + Q Y+A+ + R+A H +R Sbjct: 1 MLTLVLGGARSGKSVFAEQLVG-----AQSCLYVATA--RPFEGEFDADFRSRIATHIER 53 Query: 61 RPGHWSTVETDDITTQLR--QVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTID 118 RP +W+T + D+ L+ Q+ LVDDLGTWLT +D+ +AW+ P + D Sbjct: 54 RPKYWNTNDQHDLIEILKNEQLDHDTLLVDDLGTWLTHILDTQKAWD--DPTQLVSTVCD 111 Query: 119 DMLAAVGEFGST--LVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAG 176 D++AA+ G +++VSPEVG+ ++P+ +GRRF D +G +N +AA CDRVVLVVAG Sbjct: 112 DLVAALSAAGKNRNIIVVSPEVGMGIIPSHPAGRRFRDSIGKVNAAVAACCDRVVLVVAG 171 Query: 177 QAVPIKP 183 A+ +KP Sbjct: 172 LALELKP 178 >tr|B5I256|B5I256_9ACTO Tax_Id=463191 SubName: Full=Adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase;[Streptomyces sviceus ATCC 29083] Length = 335 Score = 132 bits (331), Expect = 2e-29 Identities = 86/187 (45%), Positives = 107/187 (57%), Gaps = 17/187 (9%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG RSGKS AE + P+ V Y+A+G W RV HR+RR Sbjct: 159 RTLVLGGARSGKSVEAERRL--EAFPD--VLYVATG----GSRNGDTEWASRVTAHRERR 210 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWE------GGSPPAALQD 115 PG W T ET D+ L+ P LVD L WLT AMD+ AW+ GG L+ Sbjct: 211 PGSWRTTETCDLVPLLKD-DGAPLLVDCLSLWLTDAMDAVGAWDDAEWADGGE--RELRS 267 Query: 116 TIDDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVA 175 + ++ AV E T+V VS EVG +VPATASGRR+ DELG LN A C++VVLVVA Sbjct: 268 RVRELTQAVREARRTVVAVSNEVGSGIVPATASGRRYRDELGRLNAAFAGECEQVVLVVA 327 Query: 176 GQAVPIK 182 GQA+ ++ Sbjct: 328 GQAMVLR 334 >tr|Q7U2G0|Q7U2G0_MYCBO Tax_Id=1765 (cobU)SubName: Full=PUTATIVE BIFUNCTIONAL COBALAMIN BIOSYNTHESIS PROTEIN COBU: COBINAMIDE KINASE + COBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE; EC=2.-.-.-;[Mycobacterium bovis] Length = 174 Score = 131 bits (329), Expect = 4e-29 Identities = 81/183 (44%), Positives = 107/183 (58%), Gaps = 11/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKS AE + D+ V Y+A G WD RVA HR R Sbjct: 1 MRILVTGGVRSGKSTHAEALLGDAAD----VVYVAPG---RPAAGSDPDWDARVALHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPP--AALQDTID 118 RP W TVET D+ T L + +P LVD LGTWLT+ MD W + A L+ +D Sbjct: 54 RPPTWLTVETADVATALSEAR-SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLD 112 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 + AA+ T ++V+ EVGL VVP+ +SG F D LGT+N+R+AA+CD V LV+AG+ Sbjct: 113 GLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRV 171 Query: 179 VPI 181 + + Sbjct: 172 LKL 174 >tr|O53676|O53676_MYCTU Tax_Id=1773 (cobU)SubName: Full=Cobinamide kinase/cobinamide phosphate guanylyltransferase; SubName: Full=PROBABLE BIFUNCTIONAL COBALAMIN BIOSYNTHESIS PROTEIN COBU: COBINAMIDE KINASE + COBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE; EC=2.-.-.-;[Mycobacterium tuberculosis] Length = 174 Score = 131 bits (329), Expect = 4e-29 Identities = 81/183 (44%), Positives = 107/183 (58%), Gaps = 11/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKS AE + D+ V Y+A G WD RVA HR R Sbjct: 1 MRILVTGGVRSGKSTHAEALLGDAAD----VVYVAPG---RPAAGSDPDWDARVALHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPP--AALQDTID 118 RP W TVET D+ T L + +P LVD LGTWLT+ MD W + A L+ +D Sbjct: 54 RPPTWLTVETADVATALSEAR-SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLD 112 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 + AA+ T ++V+ EVGL VVP+ +SG F D LGT+N+R+AA+CD V LV+AG+ Sbjct: 113 GLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRV 171 Query: 179 VPI 181 + + Sbjct: 172 LKL 174 >tr|C6DRR1|C6DRR1_MYCTK Tax_Id=478434 SubName: Full=Bifunctional cobalamin biosynthesis protein cobU;[Mycobacterium tuberculosis] Length = 174 Score = 131 bits (329), Expect = 4e-29 Identities = 81/183 (44%), Positives = 107/183 (58%), Gaps = 11/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKS AE + D+ V Y+A G WD RVA HR R Sbjct: 1 MRILVTGGVRSGKSTHAEALLGDAAD----VVYVAPG---RPAAGSDPDWDARVALHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPP--AALQDTID 118 RP W TVET D+ T L + +P LVD LGTWLT+ MD W + A L+ +D Sbjct: 54 RPPTWLTVETADVATALSEAR-SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLD 112 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 + AA+ T ++V+ EVGL VVP+ +SG F D LGT+N+R+AA+CD V LV+AG+ Sbjct: 113 GLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRV 171 Query: 179 VPI 181 + + Sbjct: 172 LKL 174 >tr|C1AJT0|C1AJT0_MYCBT Tax_Id=561275 (cobU)SubName: Full=Putative cobalamin biosynthesis protein;[Mycobacterium bovis] Length = 174 Score = 131 bits (329), Expect = 4e-29 Identities = 81/183 (44%), Positives = 107/183 (58%), Gaps = 11/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKS AE + D+ V Y+A G WD RVA HR R Sbjct: 1 MRILVTGGVRSGKSTHAEALLGDAAD----VVYVAPG---RPAAGSDPDWDARVALHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPP--AALQDTID 118 RP W TVET D+ T L + +P LVD LGTWLT+ MD W + A L+ +D Sbjct: 54 RPPTWLTVETADVATALSEAR-SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLD 112 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 + AA+ T ++V+ EVGL VVP+ +SG F D LGT+N+R+AA+CD V LV+AG+ Sbjct: 113 GLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRV 171 Query: 179 VPI 181 + + Sbjct: 172 LKL 174 >tr|A5TYY0|A5TYY0_MYCTA Tax_Id=419947 (cobU)SubName: Full=Cobinamide kinase/cobinamide phosphate guanylyltransferase;[Mycobacterium tuberculosis] Length = 174 Score = 131 bits (329), Expect = 4e-29 Identities = 81/183 (44%), Positives = 107/183 (58%), Gaps = 11/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKS AE + D+ V Y+A G WD RVA HR R Sbjct: 1 MRILVTGGVRSGKSTHAEALLGDAAD----VVYVAPG---RPAAGSDPDWDARVALHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPP--AALQDTID 118 RP W TVET D+ T L + +P LVD LGTWLT+ MD W + A L+ +D Sbjct: 54 RPPTWLTVETADVATALSEAR-SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLD 112 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 + AA+ T ++V+ EVGL VVP+ +SG F D LGT+N+R+AA+CD V LV+AG+ Sbjct: 113 GLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRV 171 Query: 179 VPI 181 + + Sbjct: 172 LKL 174 >tr|A1KF75|A1KF75_MYCBP Tax_Id=410289 (cobU)SubName: Full=Putative bifunctional cobalamin biosynthesis protein cobU: cobinamide kinase + cobinamide phosphate guanylyltransferase; EC=2.-.-.-;[Mycobacterium bovis] Length = 174 Score = 131 bits (329), Expect = 4e-29 Identities = 81/183 (44%), Positives = 107/183 (58%), Gaps = 11/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKS AE + D+ V Y+A G WD RVA HR R Sbjct: 1 MRILVTGGVRSGKSTHAEALLGDAAD----VVYVAPG---RPAAGSDPDWDARVALHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPP--AALQDTID 118 RP W TVET D+ T L + +P LVD LGTWLT+ MD W + A L+ +D Sbjct: 54 RPPTWLTVETADVATALSEAR-SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLD 112 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 + AA+ T ++V+ EVGL VVP+ +SG F D LGT+N+R+AA+CD V LV+AG+ Sbjct: 113 GLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRV 171 Query: 179 VPI 181 + + Sbjct: 172 LKL 174 >tr|A5WIW1|A5WIW1_MYCTF Tax_Id=336982 SubName: Full=Bifunctional cobalamin biosynthesis protein cobU: cobinamide kinase + cobinamide phosphate guanylyltransferase;[Mycobacterium tuberculosis] Length = 174 Score = 131 bits (329), Expect = 4e-29 Identities = 81/183 (44%), Positives = 107/183 (58%), Gaps = 11/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKS AE + D+ V Y+A G WD RVA HR R Sbjct: 1 MRILVTGGVRSGKSTHAEALLGDAAD----VVYVAPG---RPAAGSDPDWDARVALHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPP--AALQDTID 118 RP W TVET D+ T L + +P LVD LGTWLT+ MD W + A L+ +D Sbjct: 54 RPPTWLTVETADVATALSEAR-SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLD 112 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 + AA+ T ++V+ EVGL VVP+ +SG F D LGT+N+R+AA+CD V LV+AG+ Sbjct: 113 GLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRV 171 Query: 179 VPI 181 + + Sbjct: 172 LKL 174 >tr|A2VNG9|A2VNG9_MYCTU Tax_Id=348776 SubName: Full=Bifunctional cobalamin biosynthesis protein cobU : cobinamide kinase + cobinamide phosphate guanylyltransferase;[Mycobacterium tuberculosis C] Length = 174 Score = 131 bits (329), Expect = 4e-29 Identities = 81/183 (44%), Positives = 107/183 (58%), Gaps = 11/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKS AE + D+ V Y+A G WD RVA HR R Sbjct: 1 MRILVTGGVRSGKSTHAEALLGDAAD----VVYVAPG---RPAAGSDPDWDARVALHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPP--AALQDTID 118 RP W TVET D+ T L + +P LVD LGTWLT+ MD W + A L+ +D Sbjct: 54 RPPTWLTVETADVATALSEAR-SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLD 112 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 + AA+ T ++V+ EVGL VVP+ +SG F D LGT+N+R+AA+CD V LV+AG+ Sbjct: 113 GLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRV 171 Query: 179 VPI 181 + + Sbjct: 172 LKL 174 >tr|B1VZP0|B1VZP0_STRGG Tax_Id=455632 SubName: Full=Putative adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase;[Streptomyces griseus subsp. griseus] Length = 400 Score = 130 bits (328), Expect = 5e-29 Identities = 83/185 (44%), Positives = 109/185 (58%), Gaps = 13/185 (7%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 R LV GG RSGKS AE+ + PE V Y+A+G W R+ HR+RR Sbjct: 224 RVLVTGGARSGKSLEAEQRL--ETFPE--VVYVATG----GRRDGDPEWAARIGLHRERR 275 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEG----GSPPAALQDTI 117 PG W T ET ++ +L P L+D L WLT AMD AWE G AAL++ + Sbjct: 276 PGAWRTEETCELV-ELLGADGPPLLIDCLSLWLTDAMDRVEAWEDERWRGGGEAALRERV 334 Query: 118 DDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 +++AAV +VLV+ EVG VVPATA+GRRF DELG LN +AA C++V+LVVAGQ Sbjct: 335 AELVAAVRGTRRPVVLVTNEVGSGVVPATAAGRRFRDELGRLNAAVAAECEQVLLVVAGQ 394 Query: 178 AVPIK 182 + ++ Sbjct: 395 VLVLR 399 >tr|C4RMI1|C4RMI1_9ACTO Tax_Id=219305 SubName: Full=Cobalbumin biosynthesis protein; Flags: Fragment;[Micromonospora sp. ATCC 39149] Length = 419 Score = 130 bits (327), Expect = 7e-29 Identities = 84/188 (44%), Positives = 106/188 (56%), Gaps = 18/188 (9%) Query: 4 LVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRRPG 63 LVLGGIRSGKS +AE +AD+ T VRY+A+ W R+ HR RRPG Sbjct: 10 LVLGGIRSGKSEFAESLVADAPT----VRYVATSAAGDPEDAE---WAARLRAHRSRRPG 62 Query: 64 HWSTVETDDITTQLRQV-----PDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTID 118 W+T ET D +L V P+ LVDDLG W+T +D PA TI Sbjct: 63 GWTTEETADDPRRLADVVASARPNETLLVDDLGGWVTVLLDP------AHQPADDTATIA 116 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 ++ AV + + +VLVSPEVGL++VP T GR F D LG N+ +A CD VVLVVAGQA Sbjct: 117 ELAEAVRDSPARVVLVSPEVGLSLVPTTPLGRAFTDALGAANRAVADACDAVVLVVAGQA 176 Query: 179 VPIKPSRA 186 +K + A Sbjct: 177 CWLKTAAA 184 >tr|A4KNS2|A4KNS2_MYCTU Tax_Id=395095 SubName: Full=Bifunctional cobalamin biosynthesis protein cobU : cobinamide kinase + cobinamide phosphate guanylyltransferase;[Mycobacterium tuberculosis str. Haarlem] Length = 174 Score = 130 bits (327), Expect = 7e-29 Identities = 80/183 (43%), Positives = 107/183 (58%), Gaps = 11/183 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MR LV GG+RSGKS AE + D+ V Y+A G WD RVA HR R Sbjct: 1 MRILVTGGVRSGKSTHAEALLGDAAD----VVYVAPG---RPAAGSDPDWDARVALHRAR 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPP--AALQDTID 118 RP W TVET D+ T L + +P LVD LGTWLT+ MD W + A L+ +D Sbjct: 54 RPPTWLTVETADVATALSEAR-SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLD 112 Query: 119 DMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQA 178 + AA+ + +V+ + EVGL VVP+ +SG F D LGT+N+R+AA+CD V LV+AG+ Sbjct: 113 GLCAALTGLPTAIVMTN-EVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRV 171 Query: 179 VPI 181 + + Sbjct: 172 LKL 174 >tr|C8NQ52|C8NQ52_COREF Tax_Id=196164 (cobU)SubName: Full=Cobinamide kinase/cobinamide phosphate guanylyltransferase; EC=2.7.1.156; EC=2.7.7.62;[Corynebacterium efficiens YS-314] Length = 172 Score = 129 bits (323), Expect = 2e-28 Identities = 79/182 (43%), Positives = 104/182 (57%), Gaps = 14/182 (7%) Query: 5 VLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRRPGH 64 +LGG RSGKS +AEE PV Y+A+ + R+A H RRP Sbjct: 1 MLGGARSGKSVFAEEIAGPG-----PVVYVATA----RPWPGDEDFAARIAAHVARRPAG 51 Query: 65 WSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDS--HRAWEGGSPPAALQDTIDDMLA 122 W+T + D+ T LR+ LVDDLGTWLT D+ AWE P L +D ++ Sbjct: 52 WTTEDRRDVVTLLREPTSATMLVDDLGTWLTHVTDTCGTPAWEHDHP--GLTAEMDALVD 109 Query: 123 AVGEF-GSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVPI 181 AV + G LV+V+PEVG+ V+P SGR F D +GTLNQR+A +C+RVVLVVAG + + Sbjct: 110 AVATYSGGNLVIVTPEVGMAVIPEHRSGRLFRDRIGTLNQRLATVCERVVLVVAGLPLEL 169 Query: 182 KP 183 KP Sbjct: 170 KP 171 >tr|C6W9E8|C6W9E8_ACTMD Tax_Id=446462 SubName: Full=Cobalbumin biosynthesis protein; Flags: Precursor;[Actinosynnema mirum] Length = 180 Score = 126 bits (316), Expect = 1e-27 Identities = 79/182 (43%), Positives = 97/182 (53%), Gaps = 12/182 (6%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 +RTLVLGG RSGKS AE L Y+A+ WD R+ARH Sbjct: 3 LRTLVLGGTRSGKSAHAE-----GLLTSPDATYVATA----RRYPDDPDWDARIARHVRS 53 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDM 120 RP W T E L P +VDDL TWLT+ +D AWEGG ++ + Sbjct: 54 RPASWRTAEVPSGLPALLPSLTGPVIVDDLATWLTNVLDDANAWEGGGADE-VEAGCAAL 112 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVP 180 + AV LVLVS EVGL VVP+T SGR F D LG+LN R+A +CD V LVVAG +P Sbjct: 113 VDAVAAVTFRLVLVSAEVGLGVVPSTRSGRLFRDHLGSLNARLAEVCDEVTLVVAG--IP 170 Query: 181 IK 182 ++ Sbjct: 171 LR 172 >tr|B5GV02|B5GV02_STRCL Tax_Id=443255 SubName: Full=Bifunctional cobalamin biosynthesis protein cobU; Flags: Fragment;[Streptomyces clavuligerus ATCC 27064] Length = 313 Score = 125 bits (315), Expect = 2e-27 Identities = 85/187 (45%), Positives = 104/187 (55%), Gaps = 17/187 (9%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLV GG RSGKS AE L V Y+A+G W RVA HR+RR Sbjct: 137 RTLVTGGARSGKSVEAERR----LETFPGVLYVATG----GGRGGDTEWADRVALHRERR 188 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWE------GGSPPAALQD 115 P W T ET ++ L P L+D L WLT AMD AW+ GG L+ Sbjct: 189 PNSWRTEETCELVPLLSG-DGPPLLLDCLSLWLTDAMDRVGAWDDERWRQGGE--RELRK 245 Query: 116 TIDDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVA 175 + +++ AV G T+V V+ EVG VVPATASGRRF DELG LN AA C++VVLVVA Sbjct: 246 RVGELVTAVRTTGRTVVAVTNEVGSGVVPATASGRRFRDELGRLNAAFAAECEQVVLVVA 305 Query: 176 GQAVPIK 182 GQA+ ++ Sbjct: 306 GQALVLR 312 >tr|C7MXA5|C7MXA5_SACVD Tax_Id=471857 SubName: Full=Adenosylcobinamide kinase;[Saccharomonospora viridis] Length = 208 Score = 125 bits (313), Expect = 3e-27 Identities = 82/179 (45%), Positives = 97/179 (54%), Gaps = 9/179 (5%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG+RSGKSR AEE ++ RY+ W RVA HR RR Sbjct: 36 RTLVLGGVRSGKSRHAEELMSG-------YRYVTYVAGSAPPTGDDPEWAARVAAHRARR 88 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSP-PAALQDTIDDM 120 P HW T+ET DI LRQV +P L+D LGTWL + AWE A+ + + D Sbjct: 89 PAHWRTIETLDIAGTLRQVT-SPVLIDCLGTWLARVLGEVGAWEQRPGWQRAVDERLQDF 147 Query: 121 LAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAV 179 + A +V VS EVG VVPAT SGR F D LG LN +AA D V LVVAG+ V Sbjct: 148 VDAWQTTTVPVVAVSNEVGSGVVPATHSGRVFRDVLGALNTAVAAGADSVRLVVAGRVV 206 >tr|C9NGG5|C9NGG5_9ACTO Tax_Id=591167 SubName: Full=Cobalbumin biosynthesis protein;[Streptomyces flavogriseus ATCC 33331] Length = 321 Score = 124 bits (312), Expect = 4e-27 Identities = 81/185 (43%), Positives = 105/185 (56%), Gaps = 13/185 (7%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLV GG RSGKS AE+ + PE V Y+A+G W R+ HR+RR Sbjct: 145 RTLVTGGARSGKSVEAEQRL--ETFPE--VVYVATG----GRREGDVEWAARIGLHRERR 196 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGG----SPPAALQDTI 117 P W T ET ++T L + P L+D L WLT AMD AW+ G L++ + Sbjct: 197 PAAWRTEETCELTGLLEE-DGPPLLIDCLSLWLTDAMDRVGAWDDGRWADGGEEKLRERV 255 Query: 118 DDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 ++ AV T+V V+ E G VVPATASGRRF DELG LN AA C++V+LVVAGQ Sbjct: 256 AELARAVRGTRRTVVAVTNETGSGVVPATASGRRFRDELGRLNAAFAAECEQVLLVVAGQ 315 Query: 178 AVPIK 182 A+ ++ Sbjct: 316 ALVLR 320 >tr|D1A8Z3|D1A8Z3_THECU Tax_Id=471852 SubName: Full=Cobalbumin biosynthesis protein;[Thermomonospora curvata DSM 43183] Length = 318 Score = 124 bits (310), Expect = 6e-27 Identities = 77/181 (42%), Positives = 104/181 (57%), Gaps = 12/181 (6%) Query: 2 RTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDRR 61 RTLVLGG+RSGKS AE +A P+ V Y+A+ W R+ HR RR Sbjct: 150 RTLVLGGVRSGKSAEAELRLA--ACPQ--VTYVATAAPAGGDAE----WAARIEAHRRRR 201 Query: 62 PGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDML 121 P W TVET D+ LR LVD +G+WL + MD AW+ P+ L+ +++++ Sbjct: 202 PHWWRTVETTDLAGVLRSATGA-VLVDGIGSWLAAVMDETGAWDD---PSRLEPRLEELV 257 Query: 122 AAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVPI 181 AA + +V VS EVGL VP TA+GR F D LG LNQR+AA + VLVVAG+ + + Sbjct: 258 AAWRATRARVVAVSDEVGLAPVPLTAAGRAFGDRLGRLNQRLAAESEEAVLVVAGRVLEL 317 Query: 182 K 182 + Sbjct: 318 R 318 >tr|C5VDB9|C5VDB9_9CORY Tax_Id=553207 (cobU)SubName: Full=Cobinamide kinase / cobinamide phosphate guanyltransferase; EC=2.7.1.156; EC=2.7.7.62;[Corynebacterium matruchotii ATCC 14266] Length = 177 Score = 124 bits (310), Expect = 6e-27 Identities = 71/188 (37%), Positives = 106/188 (56%), Gaps = 14/188 (7%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTL+LGG RSGKS +AE+ + + Y+A+ + +R+ +H++R Sbjct: 1 MRTLILGGARSGKSAFAEQLVITT-----DCLYVATA----RPWSNDADFAERIHQHQNR 51 Query: 61 RPGHWSTVETDDITTQLRQV-PDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDD 119 RP W T + D+ L P+ LVDDLGTW+T +D+H AW+ P + D Sbjct: 52 RPPAWRTEDQKDVIEVLHATTPEATILVDDLGTWVTHTIDAHHAWD--CPRGTMAAHYAD 109 Query: 120 MLAAVGEFGS--TLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 ++ + F L++VSPEVG+ ++P +GR F DELG LN ++A CD+V VVAG Sbjct: 110 LVKGIAAFPPHRDLIIVSPEVGMGIIPEHRAGRLFRDELGFLNAQVAQACDQVFFVVAGL 169 Query: 178 AVPIKPSR 185 + +KPSR Sbjct: 170 PLQLKPSR 177 >tr|C0E4I5|C0E4I5_9CORY Tax_Id=566549 SubName: Full=Putative uncharacterized protein;[Corynebacterium matruchotii ATCC 33806] Length = 177 Score = 122 bits (307), Expect = 1e-26 Identities = 71/188 (37%), Positives = 104/188 (55%), Gaps = 14/188 (7%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 MRTLVLGG RSGKS +AE+ + + Y+A+ + +R+ +H+ R Sbjct: 1 MRTLVLGGARSGKSAFAEQLVITT-----DCLYVATA----RPWSDDTDFAERIHQHQSR 51 Query: 61 RPGHWSTVETDDITTQLRQV-PDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDD 119 RP W T + D+ L P+ LVDDLGTW+T +D+H AW+ P + D Sbjct: 52 RPPAWRTEDQKDVIEVLHATTPEATILVDDLGTWVTHTIDAHHAWD--CPRGTMAAHYAD 109 Query: 120 MLAAVGEFGS--TLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 ++ + F L++VSPEVG+ ++P +GR F DELG LN ++A CD+V VVAG Sbjct: 110 LVKGIAAFPPHRDLIIVSPEVGMGIIPERRTGRLFRDELGFLNAQVAQACDQVFFVVAGL 169 Query: 178 AVPIKPSR 185 + +KP R Sbjct: 170 PLQLKPGR 177 >tr|A1SJM9|A1SJM9_NOCSJ Tax_Id=196162 SubName: Full=Adenosylcobinamide kinase; EC=2.7.1.156;[Nocardioides sp.] Length = 173 Score = 121 bits (304), Expect = 3e-26 Identities = 79/182 (43%), Positives = 96/182 (52%), Gaps = 14/182 (7%) Query: 1 MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPXXXXXXXXXXXWDQRVARHRDR 60 M+ LV GG+RSGKS AE + E V Y+A GP W RVA HR R Sbjct: 1 MKVLVTGGVRSGKSTHAEALVR----AEPAVTYVAPGPAQDDAD-----WAARVAAHRAR 51 Query: 61 RPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAA--LQDTID 118 RP W+T+ET D+ LR P LVD LGTWLT +D WE S A + + Sbjct: 52 RPATWTTLETGDLAAALRT--PGPVLVDCLGTWLTRQVDEAGLWEAESDAVAAYVDARVS 109 Query: 119 DMLAAV-GEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ 177 + L + G +VLV+ EVGL VVP SGR F D LG +NQR CD V LVVAG+ Sbjct: 110 EALTVLAGRPDGPVVLVTNEVGLGVVPEHRSGRLFRDLLGVVNQRFGPACDEVHLVVAGR 169 Query: 178 AV 179 + Sbjct: 170 VL 171 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.317 0.132 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 1,346,999,012 Number of extensions: 50306378 Number of successful extensions: 128923 Number of sequences better than 10.0: 903 Number of HSP's gapped: 128775 Number of HSP's successfully gapped: 914 Length of query: 186 Length of database: 3,846,993,858 Length adjustment: 129 Effective length of query: 57 Effective length of database: 2,392,492,671 Effective search space: 136372082247 Effective search space used: 136372082247 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 76 (33.9 bits)