BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MMAR_3253
         (252 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,275,203 sequences; 3,846,993,858 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|A0PTP3|COBS_MYCUA Tax_Id=362242 (cobS)RecName: Full=Cobalamin...   270   1e-70
sp|B2HGX7|COBS_MYCMM Tax_Id=216594 (cobS)RecName: Full=Cobalamin...   270   1e-70
sp|C1AQC3|COBS_MYCBT Tax_Id=561275 (cobS)RecName: Full=Cobalamin...   210   1e-52
sp|A1KKQ0|COBS_MYCBP Tax_Id=410289 (cobS)RecName: Full=Cobalamin...   210   1e-52
sp|Q7VEN6|COBS_MYCBO Tax_Id=1765 (cobS)RecName: Full=Cobalamin s...   210   1e-52
sp|Q10397|COBS_MYCTU Tax_Id=1773 (cobS)RecName: Full=Cobalamin s...   208   5e-52
sp|A5U4N6|COBS_MYCTA Tax_Id=419947 (cobS)RecName: Full=Cobalamin...   208   5e-52
tr|C6DPK0|C6DPK0_MYCTK Tax_Id=478434 SubName: Full=Cobalamin 5-p...   208   5e-52
tr|A5WPH8|A5WPH8_MYCTF Tax_Id=336982 SubName: Full=Cobalamin 5-p...   208   5e-52
tr|A2VJU9|A2VJU9_MYCTU Tax_Id=348776 SubName: Full=Cobalamin 5-p...   208   5e-52
tr|A4KIX8|A4KIX8_MYCTU Tax_Id=395095 SubName: Full=Cobalamin 5-p...   207   7e-52
sp|Q73YK6|COBS_MYCPA Tax_Id=1770 (cobS)RecName: Full=Cobalamin s...   204   1e-50
sp|A0QEZ8|COBS_MYCA1 Tax_Id=243243 (cobS)RecName: Full=Cobalamin...   203   1e-50
sp|A0R065|COBS_MYCS2 Tax_Id=246196 (cobS)RecName: Full=Cobalamin...   179   3e-43
sp|Q1B6S1|COBS_MYCSS Tax_Id=164756 (cobS)RecName: Full=Cobalamin...   171   7e-41
sp|A1UIA4|COBS_MYCSK Tax_Id=189918 (cobS)RecName: Full=Cobalamin...   171   7e-41
sp|A3Q1R8|COBS_MYCSJ Tax_Id=164757 (cobS)RecName: Full=Cobalamin...   169   2e-40
sp|A1TB16|COBS_MYCVP Tax_Id=350058 (cobS)RecName: Full=Cobalamin...   160   9e-38
sp|A4TBJ8|COBS_MYCGI Tax_Id=350054 (cobS)RecName: Full=Cobalamin...   160   2e-37
tr|B1MNY3|B1MNY3_MYCA9 Tax_Id=561007 SubName: Full=Cobalamin syn...   149   3e-34
tr|Q5YZ46|Q5YZ46_NOCFA Tax_Id=37329 (cobS)SubName: Full=Putative...   117   2e-24
tr|C1AUB2|C1AUB2_RHOOB Tax_Id=632772 (cobV)SubName: Full=Cobalam...   115   5e-24
tr|C1A133|C1A133_RHOE4 Tax_Id=234621 (cobV)SubName: Full=Cobalam...   114   8e-24
tr|C3JJB0|C3JJB0_RHOER Tax_Id=596309 (cobS)SubName: Full=Cobalam...   114   1e-23
tr|Q0SHL3|Q0SHL3_RHOSR Tax_Id=101510 (cobS)SubName: Full=Cobalam...   113   2e-23
tr|C2ASV0|C2ASV0_TSUPA Tax_Id=521096 SubName: Full=Cobalamin-5-p...   111   7e-23
tr|C6W9E6|C6W9E6_ACTMD Tax_Id=446462 SubName: Full=Cobalamin 5'-...   110   1e-22
tr|A4FA93|A4FA93_SACEN Tax_Id=405948 (cobS)SubName: Full=Putativ...   109   3e-22
tr|C4RMI3|C4RMI3_9ACTO Tax_Id=219305 SubName: Full=Cobalamin-5-p...   108   6e-22
tr|A8LYE0|A8LYE0_SALAI Tax_Id=391037 SubName: Full=Cobalamin-5-p...    97   2e-18
tr|A4XA08|A4XA08_SALTO Tax_Id=369723 SubName: Full=Cobalamin-5'-...    93   3e-17
tr|D0LAY2|D0LAY2_GORB4 Tax_Id=526226 SubName: Full=Cobalamin-5-p...    91   9e-17
tr|C8XJ12|C8XJ12_NAKMY Tax_Id=479431 SubName: Full=Cobalamin-5-p...    85   9e-15
tr|A3TS68|A3TS68_9MICO Tax_Id=313589 SubName: Full=Putative coba...    80   2e-13
tr|C9YTS0|C9YTS0_STRSW Tax_Id=680198 (cobS)SubName: Full=Putativ...    79   5e-13
sp|A1SJN0|COBS_NOCSJ Tax_Id=196162 (cobS)RecName: Full=Cobalamin...    78   1e-12
tr|C7MXA3|C7MXA3_SACVD Tax_Id=471857 SubName: Full=Cobalamin-5-p...    78   1e-12
tr|B1VZN6|B1VZN6_STRGG Tax_Id=455632 SubName: Full=Putative coba...    76   4e-12
tr|Q9S2Q9|Q9S2Q9_STRCO Tax_Id=1902 SubName: Full=Putative cobala...    75   7e-12
tr|Q82AN1|Q82AN1_STRAW Tax_Id=33903 (cobS)SubName: Full=Putative...    74   2e-11
tr|C1YQE9|C1YQE9_NOCDA Tax_Id=446468 SubName: Full=Cobalamin-5'-...    72   6e-11
tr|D1A8Z4|D1A8Z4_THECU Tax_Id=471852 SubName: Full=Cobalamin-5-p...    72   8e-11
tr|C0UBB7|C0UBB7_9ACTO Tax_Id=526225 SubName: Full=Cobalamin-5-p...    70   3e-10
tr|C7QD50|C7QD50_CATAD Tax_Id=479433 SubName: Full=Cobalamin-5-p...    69   4e-10
tr|Q47R83|Q47R83_THEFY Tax_Id=269800 SubName: Full=Cobalamin-5'-...    67   2e-09
tr|B5GV05|B5GV05_STRCL Tax_Id=443255 SubName: Full=Cobalamin syn...    67   2e-09
tr|B4V3K8|B4V3K8_9ACTO Tax_Id=465541 SubName: Full=Cobalamin syn...    66   4e-09
tr|A8LFB8|A8LFB8_FRASN Tax_Id=298653 SubName: Full=Cobalamin 5'-...    65   5e-09
sp|Q2J8A4|COBS_FRASC Tax_Id=106370 (cobS)RecName: Full=Cobalamin...    60   2e-07
tr|Q75NF3|Q75NF3_PROFR Tax_Id=1752 (cobS)SubName: Full=Cobalamin...    60   3e-07

>sp|A0PTP3|COBS_MYCUA Tax_Id=362242 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium ulcerans]
          Length = 252

 Score =  270 bits (689), Expect = 1e-70
 Identities = 151/236 (63%), Positives = 152/236 (64%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           +IRSLATALSFGTVIPVPASVAAPMGRGAMT                TWSASLVF     
Sbjct: 1   MIRSLATALSFGTVIPVPASVAAPMGRGAMTALPVVGVVLGGLAAGVTWSASLVFGPVSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LPGLLAVAVLLLATRGLHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           VQGSAFSTL                    TAVLGCRRSVPAAAGSSLGSRVAGTQPIS  
Sbjct: 121 VQGSAFSTLSAAGSRGIAGIAVAVFAGRVTAVLGCRRSVPAAAGSSLGSRVAGTQPISVL 180

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         GTLLIRHCVRRFGGITGDVLGCAIE
Sbjct: 181 VAWLAVLLFASLAAAPRPWQGPAAVVAAVCAGTLLIRHCVRRFGGITGDVLGCAIE 236


>sp|B2HGX7|COBS_MYCMM Tax_Id=216594 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium marinum]
          Length = 252

 Score =  270 bits (689), Expect = 1e-70
 Identities = 151/236 (63%), Positives = 152/236 (64%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           +IRSLATALSFGTVIPVPASVAAPMGRGAMT                TWSASLVF     
Sbjct: 1   MIRSLATALSFGTVIPVPASVAAPMGRGAMTALPVVGVVLGGLAAGVTWSASLVFGPVSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LPGLLAVAVLLLATRGLHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           VQGSAFSTL                    TAVLGCRRSVPAAAGSSLGSRVAGTQPIS  
Sbjct: 121 VQGSAFSTLSAAGSRGIAGIAVAVFAGRVTAVLGCRRSVPAAAGSSLGSRVAGTQPISVL 180

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         GTLLIRHCVRRFGGITGDVLGCAIE
Sbjct: 181 VAWLAVLLFASLAAAPRPWQGPAAVVAAVCAGTLLIRHCVRRFGGITGDVLGCAIE 236


>sp|C1AQC3|COBS_MYCBT Tax_Id=561275 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium bovis]
          Length = 249

 Score =  210 bits (535), Expect = 1e-52
 Identities = 120/236 (50%), Positives = 129/236 (54%), Gaps = 3/236 (1%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +F TVIP P S   PMGRG MT                 W+ + VF     
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           +QG AF+TL                    TAVL CRRSVPAA GS+LGSRVAGTQP    
Sbjct: 121 LQGLAFATL---TTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVV 177

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         G  L  HCV RFGG+TGDVLG AIE
Sbjct: 178 AAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIE 233


>sp|A1KKQ0|COBS_MYCBP Tax_Id=410289 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium bovis]
          Length = 249

 Score =  210 bits (535), Expect = 1e-52
 Identities = 120/236 (50%), Positives = 129/236 (54%), Gaps = 3/236 (1%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +F TVIP P S   PMGRG MT                 W+ + VF     
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           +QG AF+TL                    TAVL CRRSVPAA GS+LGSRVAGTQP    
Sbjct: 121 LQGLAFATL---TTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVV 177

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         G  L  HCV RFGG+TGDVLG AIE
Sbjct: 178 AAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIE 233


>sp|Q7VEN6|COBS_MYCBO Tax_Id=1765 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium bovis]
          Length = 249

 Score =  210 bits (535), Expect = 1e-52
 Identities = 120/236 (50%), Positives = 129/236 (54%), Gaps = 3/236 (1%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +F TVIP P S   PMGRG MT                 W+ + VF     
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           +QG AF+TL                    TAVL CRRSVPAA GS+LGSRVAGTQP    
Sbjct: 121 LQGLAFATL---TTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVV 177

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         G  L  HCV RFGG+TGDVLG AIE
Sbjct: 178 AAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIE 233


>sp|Q10397|COBS_MYCTU Tax_Id=1773 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium tuberculosis]
          Length = 249

 Score =  208 bits (529), Expect = 5e-52
 Identities = 119/236 (50%), Positives = 128/236 (54%), Gaps = 3/236 (1%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +F TVIP P S   PMGRG MT                 W+ + VF     
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           +QG AF+TL                    TAVL CRR VPAA GS+LGSRVAGTQP    
Sbjct: 121 LQGLAFATL---TTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVV 177

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         G  L  HCV RFGG+TGDVLG AIE
Sbjct: 178 AAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIE 233


>sp|A5U4N6|COBS_MYCTA Tax_Id=419947 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium tuberculosis]
          Length = 249

 Score =  208 bits (529), Expect = 5e-52
 Identities = 119/236 (50%), Positives = 128/236 (54%), Gaps = 3/236 (1%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +F TVIP P S   PMGRG MT                 W+ + VF     
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           +QG AF+TL                    TAVL CRR VPAA GS+LGSRVAGTQP    
Sbjct: 121 LQGLAFATL---TTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVV 177

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         G  L  HCV RFGG+TGDVLG AIE
Sbjct: 178 AAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIE 233


>tr|C6DPK0|C6DPK0_MYCTK Tax_Id=478434 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis]
          Length = 249

 Score =  208 bits (529), Expect = 5e-52
 Identities = 119/236 (50%), Positives = 128/236 (54%), Gaps = 3/236 (1%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +F TVIP P S   PMGRG MT                 W+ + VF     
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           +QG AF+TL                    TAVL CRR VPAA GS+LGSRVAGTQP    
Sbjct: 121 LQGLAFATL---TTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVV 177

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         G  L  HCV RFGG+TGDVLG AIE
Sbjct: 178 AAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIE 233


>tr|A5WPH8|A5WPH8_MYCTF Tax_Id=336982 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis]
          Length = 249

 Score =  208 bits (529), Expect = 5e-52
 Identities = 119/236 (50%), Positives = 128/236 (54%), Gaps = 3/236 (1%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +F TVIP P S   PMGRG MT                 W+ + VF     
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           +QG AF+TL                    TAVL CRR VPAA GS+LGSRVAGTQP    
Sbjct: 121 LQGLAFATL---TTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVV 177

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         G  L  HCV RFGG+TGDVLG AIE
Sbjct: 178 AAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIE 233


>tr|A2VJU9|A2VJU9_MYCTU Tax_Id=348776 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis C]
          Length = 249

 Score =  208 bits (529), Expect = 5e-52
 Identities = 119/236 (50%), Positives = 128/236 (54%), Gaps = 3/236 (1%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +F TVIP P S   PMGRG MT                 W+ + VF     
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           +QG AF+TL                    TAVL CRR VPAA GS+LGSRVAGTQP    
Sbjct: 121 LQGLAFATL---TTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVV 177

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP         G  L  HCV RFGG+TGDVLG AIE
Sbjct: 178 AAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIE 233


>tr|A4KIX8|A4KIX8_MYCTU Tax_Id=395095 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis
           str. Haarlem]
          Length = 248

 Score =  207 bits (528), Expect = 7e-52
 Identities = 119/235 (50%), Positives = 127/235 (54%), Gaps = 3/235 (1%)

Query: 2   IRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXXX 61
           +RSLATA +F TVIP P S   PMGRG MT                 W+ + VF      
Sbjct: 1   MRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSPL 60

Query: 62  XXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAV 121
                           HID VADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA+
Sbjct: 61  SGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAL 120

Query: 122 QGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXXX 181
           QG AF+TL                    TAVL CRR VPAA GS+LGSRVAGTQP     
Sbjct: 121 QGLAFATL---TTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVA 177

Query: 182 XXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                         PRPWQGP         G  L  HCV RFGG+TGDVLG AIE
Sbjct: 178 AWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIE 232


>sp|Q73YK6|COBS_MYCPA Tax_Id=1770 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium paratuberculosis]
          Length = 251

 Score =  204 bits (518), Expect = 1e-50
 Identities = 114/236 (48%), Positives = 129/236 (54%), Gaps = 1/236 (0%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +FGTV+PVPA    PMGRGAMT                 W  ++VF     
Sbjct: 1   MMRSLATAFAFGTVLPVPAGGRGPMGRGAMTALPVVGLALGALAAAVAWGGAVVFGRSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPP RA AVMRDGSTGPFGVAAVV+V+ 
Sbjct: 61  LGGLLAVAALLLITRGLHIDGVADTADGLGCYGPPDRARAVMRDGSTGPFGVAAVVVVVM 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
            Q  AFS L                     AVL CRR+VPAAAGSSLG+ VAG+QP +  
Sbjct: 121 AQALAFSAL-AAGRPVPVGVAVAVFAGRVAAVLACRRTVPAAAGSSLGATVAGSQPATVA 179

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPW GP         G +L+RHCVRRFGGI+GDVLG AIE
Sbjct: 180 AAWVAVLLGMSLVAGPRPWHGPVAVLLGLGCGGVLVRHCVRRFGGISGDVLGAAIE 235


>sp|A0QEZ8|COBS_MYCA1 Tax_Id=243243 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium avium]
          Length = 251

 Score =  203 bits (517), Expect = 1e-50
 Identities = 113/236 (47%), Positives = 129/236 (54%), Gaps = 1/236 (0%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++RSLATA +FGTV+P+PA    PMGRGAMT                 W  ++VF     
Sbjct: 1   MMRSLATAFAFGTVLPMPAGGRGPMGRGAMTALPVVGLALGALAAAVAWGGTVVFGRSSP 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID VADTADGLGCYGPP RA AVMRDGSTGPFGVAAVV+V+ 
Sbjct: 61  LGGLLAVAALLLITRGLHIDGVADTADGLGCYGPPDRARAVMRDGSTGPFGVAAVVVVVM 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
            Q  AFS L                     AVL CRR+VPAAAGSSLG+ VAG+QP +  
Sbjct: 121 AQALAFSAL-AAGRPVPVGVAVAVFAGRVAAVLACRRTVPAAAGSSLGAAVAGSQPATVA 179

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPW GP         G +L+RHCVRRFGGI+GDVLG AIE
Sbjct: 180 AAWVAVLLGMSLVAGPRPWHGPVAVLLGLGCGAVLVRHCVRRFGGISGDVLGAAIE 235


>sp|A0R065|COBS_MYCS2 Tax_Id=246196 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium smegmatis]
          Length = 241

 Score =  179 bits (453), Expect = 3e-43
 Identities = 106/236 (44%), Positives = 120/236 (50%), Gaps = 8/236 (3%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           +IRSLA A +FGTV+PV AS  A +GRGA+T                 W+    F     
Sbjct: 1   MIRSLAGAFAFGTVLPVRAS--AGVGRGALTALPFVGLALGALAAAVVWAGGWAFAAGSP 58

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID   DT DGLGCYGPP+RALAVMRDGS GPFGVAAVV+VIA
Sbjct: 59  LPGVLAVAVLLLATRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGVAAVVVVIA 118

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           VQ   F+ L                      V  CRRSVPAAAGS+LG+ VAG+QP    
Sbjct: 119 VQALTFAEL------SVLAVVTAVVAGRVAVVAACRRSVPAAAGSTLGAAVAGSQPRWVV 172

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                          PRPWQGP            L+ HCVRRFGGITGDVLG A+E
Sbjct: 173 AGWIVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGDVLGAAVE 228


>sp|Q1B6S1|COBS_MYCSS Tax_Id=164756 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium sp.]
          Length = 248

 Score =  171 bits (433), Expect = 7e-41
 Identities = 98/236 (41%), Positives = 116/236 (49%), Gaps = 1/236 (0%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           +I SLA A +FGTV+PVPA   A +GRG MT                 W+ S  F     
Sbjct: 1   MIGSLAGAFAFGTVLPVPAGSTATLGRGVMTALPGVGIVLGAVAAAVLWAGSWAFGPHSA 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID ++DT DGLGCYG P+RAL VMRDGS G FG A++V+ + 
Sbjct: 61  LAGLLAVAVLLLATRGMHIDGLSDTVDGLGCYGAPERALRVMRDGSAGAFGAASIVVAVG 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
            Q  AFS L                     A++ CRR +PAA GS+LG RVAGTQP +  
Sbjct: 121 AQTLAFSML-PGGWSGAVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVV 179

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                           R WQGP           LL+RHCVRRFGGITGDVLG AIE
Sbjct: 180 LVWLAAVAALAIPATERIWQGPLTVVVAVGMTALLVRHCVRRFGGITGDVLGAAIE 235


>sp|A1UIA4|COBS_MYCSK Tax_Id=189918 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium sp.]
          Length = 248

 Score =  171 bits (433), Expect = 7e-41
 Identities = 98/236 (41%), Positives = 116/236 (49%), Gaps = 1/236 (0%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           +I SLA A +FGTV+PVPA   A +GRG MT                 W+ S  F     
Sbjct: 1   MIGSLAGAFAFGTVLPVPAGSTATLGRGVMTALPGVGIVLGAVAAAVLWAGSWAFGPHSA 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID ++DT DGLGCYG P+RAL VMRDGS G FG A++V+ + 
Sbjct: 61  LAGLLAVAVLLLATRGMHIDGLSDTVDGLGCYGAPERALRVMRDGSAGAFGAASIVVAVG 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
            Q  AFS L                     A++ CRR +PAA GS+LG RVAGTQP +  
Sbjct: 121 AQTLAFSML-PGGWSGAVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVV 179

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                           R WQGP           LL+RHCVRRFGGITGDVLG AIE
Sbjct: 180 LVWLAAVAALAIPATERIWQGPLTVVVAVGMTALLVRHCVRRFGGITGDVLGAAIE 235


>sp|A3Q1R8|COBS_MYCSJ Tax_Id=164757 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium sp.]
          Length = 248

 Score =  169 bits (429), Expect = 2e-40
 Identities = 97/236 (41%), Positives = 115/236 (48%), Gaps = 1/236 (0%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           +I SLA A +FGTV+PVP    A +GRG MT                 W+ S  F     
Sbjct: 1   MIGSLAGAFAFGTVLPVPTGSTATLGRGVMTALPGVGIVLGAVAAAVLWAGSWAFGPHSA 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID ++DT DGLGCYG P+RAL VMRDGS G FG A++V+ + 
Sbjct: 61  LAGLLAVAVLLLATRGMHIDGLSDTVDGLGCYGAPERALRVMRDGSAGAFGAASIVVAVG 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
            Q  AFS L                     A++ CRR +PAA GS+LG RVAGTQP +  
Sbjct: 121 AQTLAFSML-PGGWSGAVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVV 179

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                           R WQGP           LL+RHCVRRFGGITGDVLG AIE
Sbjct: 180 LVWLAAVAALAIPATERIWQGPLTVVVAVGMTALLVRHCVRRFGGITGDVLGAAIE 235


>sp|A1TB16|COBS_MYCVP Tax_Id=350058 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium vanbaalenii]
          Length = 243

 Score =  160 bits (406), Expect = 9e-38
 Identities = 93/236 (39%), Positives = 110/236 (46%), Gaps = 6/236 (2%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           +I SL  A +F TV+P P    A +GRG +T                 W+ S  F     
Sbjct: 1   MISSLTGAFAFATVLPTPTRATAMVGRGVLTALPVAGAALGVLAAGVLWAGSWAFGDGSA 60

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID ++DT D LGCYGPP+RALAVMRDG+ GPFGVAAV   + 
Sbjct: 61  LAGVLTVAVLLLATRGLHIDGLSDTVDALGCYGPPERALAVMRDGTAGPFGVAAVAATLL 120

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
           VQ  AF+                        V  CRR VPAAAGS+LG+ V+GTQP    
Sbjct: 121 VQSLAFA------QSGWAAVFIAVVAGRVAVVAACRRGVPAAAGSTLGALVSGTQPRWVA 174

Query: 181 XXXXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                           RPWQGP            L+ HCVRRFGGITGDVLG A+E
Sbjct: 175 AGWTVAVAAAAVPVCARPWQGPLVVALALACSAGLVAHCVRRFGGITGDVLGAALE 230


>sp|A4TBJ8|COBS_MYCGI Tax_Id=350054 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium gilvum]
          Length = 243

 Score =  160 bits (404), Expect = 2e-37
 Identities = 92/234 (39%), Positives = 111/234 (47%), Gaps = 6/234 (2%)

Query: 3   RSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXXXX 62
           RSLA A +F TV+PVP+  AA  GRG +T                 W  +  F       
Sbjct: 3   RSLAGAFAFATVMPVPSRRAAIAGRGVLTALPVVGLVLGSAAAAVCWLGTRAFGSGSVLA 62

Query: 63  XXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQ 122
                          HID ++DT D LGCYGP +RALAVMRDG  GPFGVAAV + + +Q
Sbjct: 63  GALTVAVLLLATRGLHIDGLSDTTDALGCYGPAERALAVMRDGRAGPFGVAAVAVTVVIQ 122

Query: 123 GSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXXXX 182
             AFS                        V+ CRR VPAA GS+LG+ VAGTQP+     
Sbjct: 123 SVAFS------QAGWAAVLVAVAAGRVAVVVACRRGVPAAEGSTLGALVAGTQPLWVAAA 176

Query: 183 XXXXXXXXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                         R WQGP           +++ HCVRRFGGITGDVLG A+E
Sbjct: 177 WLVAIAGLATLAGERAWQGPLAVVVAVACSVVMVAHCVRRFGGITGDVLGAAVE 230


>tr|B1MNY3|B1MNY3_MYCA9 Tax_Id=561007 SubName: Full=Cobalamin
           synthase CobS;[Mycobacterium abscessus]
          Length = 252

 Score =  149 bits (376), Expect = 3e-34
 Identities = 88/237 (37%), Positives = 110/237 (46%), Gaps = 5/237 (2%)

Query: 1   VIRSLATALSFGTVIPVPASVAAPMGRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXXXX 60
           ++R +  A  F TV PVPA +A  +    +                  W   + F     
Sbjct: 7   ILRPVGGAFEFATVAPVPARLAGTLSGPVLGALPVVGAALGVLAAFVAWV--MHFAYMAP 64

Query: 61  XXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120
                            HID ++DTADGLGCYGPP+RAL VMRDGS GPFGV  +++ + 
Sbjct: 65  IAGLAAVAATILATRGLHIDGLSDTADGLGCYGPPERALTVMRDGSAGPFGVVVLIICLL 124

Query: 121 VQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXX 180
            Q  +F  L                    +AV+ CRR VP AA S  G+RVAG+QP+   
Sbjct: 125 AQALSFGVL--ASRQEWLAVALAITVGRISAVVACRRGVPGAAASGFGTRVAGSQPLWLA 182

Query: 181 XXXXXXXXXXXXXXXP-RPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                            RPWQGP         G LL+RHCVRRFGGITGDVLG +IE
Sbjct: 183 GMWVAAAMAVGLLAQTWRPWQGPVVVAVALIAGALLVRHCVRRFGGITGDVLGASIE 239


>tr|Q5YZ46|Q5YZ46_NOCFA Tax_Id=37329 (cobS)SubName: Full=Putative
           cobalamin 5'-phosphate synthase;[Nocardia farcinica]
          Length = 259

 Score =  117 bits (292), Expect = 2e-24
 Identities = 68/160 (42%), Positives = 81/160 (50%), Gaps = 4/160 (2%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG YGPP+RA  +M+ G  GPFGVAA+V  + V   AF T         
Sbjct: 88  HLDGLADTADGLGSYGPPERARQIMKGGDVGPFGVAAIVFAVGVPALAFGT--AAAEGRW 145

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQ-PISXXXXXXXXXXXXXXXXXP 196
                         VL CRR+ PAA G+  GS VA TQ P +                  
Sbjct: 146 LAIGLAVALGRVVVVLACRRA-PAAPGTGFGSLVAATQHPATGVVWTILAAVCAVFAVPG 204

Query: 197 RPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
           R W GP           LL+RHCVRRF G++GDVLG AIE
Sbjct: 205 RAWLGPLVVLVAVAAALLLVRHCVRRFEGLSGDVLGAAIE 244


>tr|C1AUB2|C1AUB2_RHOOB Tax_Id=632772 (cobV)SubName: Full=Cobalamin
           (5'-phosphate) synthase; EC=2.7.8.26;[Rhodococcus
           opacus]
          Length = 246

 Score =  115 bits (288), Expect = 5e-24
 Identities = 65/160 (40%), Positives = 80/160 (50%), Gaps = 4/160 (2%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D ++DT DGLGCYGPP+RA AVM  G  GPFGV A+V+ +  QG AF +L        
Sbjct: 78  HVDGLSDTVDGLGCYGPPERARAVMHSGGAGPFGVCALVICLGAQGLAFGSL--AAAGQF 135

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQ-PISXXXXXXXXXXXXXXXXXP 196
                         V  CRR +PA++    G+ VA TQ P S                 P
Sbjct: 136 ACVAVAMAAGRVAVVFACRRGIPASSTEGFGALVAETQSPWSGLAWTVPLLAAAAWCTSP 195

Query: 197 RPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
             WQGP           LL+ HCVRRF G+ GDVLG A+E
Sbjct: 196 W-WQGPVVVTAALTLTALLVAHCVRRFAGMNGDVLGAALE 234


>tr|C1A133|C1A133_RHOE4 Tax_Id=234621 (cobV)SubName: Full=Cobalamin
           (5'-phosphate) synthase; EC=2.7.8.26;[Rhodococcus
           erythropolis]
          Length = 255

 Score =  114 bits (286), Expect = 8e-24
 Identities = 61/160 (38%), Positives = 80/160 (50%), Gaps = 1/160 (0%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +AD+ DGLGCYGPP+RA  VM  G  GPFGVAA+ + + +Q  +F  L        
Sbjct: 82  HVDGLADSVDGLGCYGPPERAREVMHSGGAGPFGVAALFIFLGLQSVSFGVLAVADSPTQ 141

Query: 138 XXXXXXXXXXXXTAVL-GCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXP 196
                        AV+  CRR + A++ S  G+ VA +QP+                   
Sbjct: 142 WIAVLVSVAAGRVAVVFACRRGILASSPSGFGALVADSQPLWAAIVWSVPLIATSAFATD 201

Query: 197 RPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
           R W GP           L +RHCVRRFGG+ GDVLG A+E
Sbjct: 202 RWWLGPLVTASALVISVLCVRHCVRRFGGLNGDVLGFALE 241


>tr|C3JJB0|C3JJB0_RHOER Tax_Id=596309 (cobS)SubName:
           Full=Cobalamin-5-phosphate synthase;
           EC=2.-.-.-;[Rhodococcus erythropolis SK121]
          Length = 255

 Score =  114 bits (285), Expect = 1e-23
 Identities = 61/160 (38%), Positives = 79/160 (49%), Gaps = 1/160 (0%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +AD+ DGLGCYGPP+RA  VM  G  GPFGVAA+ + + +Q  +F  L        
Sbjct: 82  HVDGLADSVDGLGCYGPPERAREVMHSGGAGPFGVAALFIFLGLQSVSFGVLAVADSPTQ 141

Query: 138 XXXXXXXXXXXXTAVL-GCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXP 196
                        AV+  CRR + A+  S  G+ VA +QP+                   
Sbjct: 142 WIAVLVSVAAGRVAVVFACRRGILASGPSGFGALVADSQPLWAAIVWSVPLIAASGFATD 201

Query: 197 RPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
           R W GP           L +RHCVRRFGG+ GDVLG A+E
Sbjct: 202 RWWLGPLVTASALVISVLCVRHCVRRFGGLNGDVLGFALE 241


>tr|Q0SHL3|Q0SHL3_RHOSR Tax_Id=101510 (cobS)SubName: Full=Cobalamin
           synthase;[Rhodococcus sp.]
          Length = 246

 Score =  113 bits (283), Expect = 2e-23
 Identities = 64/160 (40%), Positives = 80/160 (50%), Gaps = 4/160 (2%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           HID ++DT DGLGCYGPP+RA AVM  G  GPFGV A+V+ +  QG AF +L        
Sbjct: 78  HIDGLSDTVDGLGCYGPPERARAVMHSGGAGPFGVCALVICLGAQGLAFGSL--AAAGQF 135

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQ-PISXXXXXXXXXXXXXXXXXP 196
                         V  C+R +PA++    G+ VA TQ P +                 P
Sbjct: 136 ACAAVAVAAGRVAVVFACQRGIPASSTEGFGALVAETQSPWTGIAWTVPLLAAAAWCTLP 195

Query: 197 RPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
             WQGP           LL+ HCVRRF G+ GDVLG A+E
Sbjct: 196 W-WQGPVVVVVALTLTALLVAHCVRRFAGLNGDVLGAALE 234


>tr|C2ASV0|C2ASV0_TSUPA Tax_Id=521096 SubName:
           Full=Cobalamin-5-phosphate synthase;[Tsukamurella
           paurometabola DSM 20162]
          Length = 250

 Score =  111 bits (278), Expect = 7e-23
 Identities = 78/239 (32%), Positives = 97/239 (40%), Gaps = 6/239 (2%)

Query: 2   IRSLATALSFGTVIPVPASVAAPM---GRGAMTXXXXXXXXXXXXXXXXTWSASLVFXXX 58
           +R L TAL++ TV+PVP  +   +   G G +                    AS      
Sbjct: 1   MRFLPTALAWMTVLPVPRRLQPAVDRPGAGRVIFFVPVAGAVVGAIVTGIAWASAAAGLP 60

Query: 59  XXXXXXXXXXXXXXXXXXXHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLV 118
                              H+D  AD  DGLG YGPP RA  +MR GS GPFG AA+ LV
Sbjct: 61  WVLIGALAIAGAALVTRGMHVDGFADCVDGLGSYGPPDRAREIMRQGSVGPFGAAALALV 120

Query: 119 IAVQGSAFSTLXXXXXXXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPIS 178
           + +  +A   L                     AV+GCRR   AA     G+  AGTQ  +
Sbjct: 121 VLIDAAAIGDL--ADRAQWIAIGVAIGAARVAAVIGCRRGWCAANPDGFGALTAGTQGGA 178

Query: 179 XXXXXXXXXXXXXXXXXPR-PWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                            P  PWQGP           L +RHCVRRFGG++GDVLG  IE
Sbjct: 179 AQAFWMFVAAIAAIWAVPDVPWQGPLAVVAAMLAAALAMRHCVRRFGGVSGDVLGFGIE 237


>tr|C6W9E6|C6W9E6_ACTMD Tax_Id=446462 SubName: Full=Cobalamin
           5'-phosphate synthase;[Actinosynnema mirum]
          Length = 237

 Score =  110 bits (275), Expect = 1e-22
 Identities = 64/159 (40%), Positives = 79/159 (49%), Gaps = 8/159 (5%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLGCYGPP+RALAVM+DG  GPFGV  +++V+  +  A   +        
Sbjct: 74  HLDGLADTADGLGCYGPPERALAVMKDGGAGPFGVVTLIVVLGAEAVALGGV------SW 127

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXPR 197
                         VL C R VPAA    LG+ VAG+Q  S                   
Sbjct: 128 GAVVLALTAGRAAFVLCCARGVPAARPEGLGALVAGSQ--SAGVVVAWWSALAVAGALVD 185

Query: 198 PWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
           PW+GP            L+ H  RRFGG+TGDVLG A E
Sbjct: 186 PWRGPLGVALAAAVVFALVGHTRRRFGGVTGDVLGAACE 224


>tr|A4FA93|A4FA93_SACEN Tax_Id=405948 (cobS)SubName: Full=Putative
           cobalamin 5'-phosphate synthase;
           EC=2.7.8.26;[Saccharopolyspora erythraea]
          Length = 244

 Score =  109 bits (272), Expect = 3e-22
 Identities = 65/159 (40%), Positives = 76/159 (47%), Gaps = 4/159 (2%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADT DGLGCYGPP+RALAVMRDG  GPF V A+VLV+ VQ  +   L        
Sbjct: 77  HVDGLADTVDGLGCYGPPERALAVMRDGGAGPFAVVALVLVLGVQAVSLGELAAAGDWAT 136

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXPR 197
                          L CR  VPAA    +G+ VAG+QP+                    
Sbjct: 137 VVVACAAGRAGF--ALCCRTGVPAARPEGMGALVAGSQPV--WAVAVWWLLLLVAAGISH 192

Query: 198 PWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
            W GP           +   H  RRFGGITGDVLG A E
Sbjct: 193 WWTGPVAVAAALAALLVFTHHVRRRFGGITGDVLGAASE 231


>tr|C4RMI3|C4RMI3_9ACTO Tax_Id=219305 SubName:
           Full=Cobalamin-5-phosphate synthase cobS;[Micromonospora
           sp. ATCC 39149]
          Length = 278

 Score =  108 bits (270), Expect = 6e-22
 Identities = 65/161 (40%), Positives = 79/161 (49%), Gaps = 2/161 (1%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADT D LG Y     AL +M+    GPFGVAA+V+V+ VQ +A + L        
Sbjct: 104 HLDGLADTVDALGSYRRGAAALEIMKKPDVGPFGVAALVVVLLVQAAALAELASRSGPAA 163

Query: 138 XXXXXXXXXXXXTAV-LGCRRSVPAAAGSSLGSRVAGTQ-PISXXXXXXXXXXXXXXXXX 195
                         V L CRR VPAA    LG+ VAGT  P++                 
Sbjct: 164 LAAMVAATAAGRLGVTLACRRGVPAARPDGLGALVAGTVGPVAAVVGTAAVALVAVAAVP 223

Query: 196 PRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
            RPWQGP           LL+RH VRR GGITGDVLG A+E
Sbjct: 224 GRPWQGPVAVLAALAVAVLLLRHAVRRLGGITGDVLGAAVE 264


>tr|A8LYE0|A8LYE0_SALAI Tax_Id=391037 SubName:
           Full=Cobalamin-5-phosphate synthase CobS;[Salinispora
           arenicola]
          Length = 257

 Score = 97.1 bits (240), Expect = 2e-18
 Identities = 59/161 (36%), Positives = 74/161 (45%), Gaps = 2/161 (1%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADT D LG Y     AL +M+    GPFGV A+V+V+ VQ +  + L        
Sbjct: 83  HLDGLADTVDALGSYRRGPAALEIMKKPDVGPFGVTALVVVLLVQAAVLAELAERSALAT 142

Query: 138 XXXXXXXXXXXXTAV-LGCRRSVPAAAGSSLGSRVAGT-QPISXXXXXXXXXXXXXXXXX 195
                         V + CRR +PAA    LG+ VAGT  P +                 
Sbjct: 143 LAAVVTATATGRLGVGVACRRGLPAARPDGLGALVAGTVGPPALAAGTVAVALLAFAAVP 202

Query: 196 PRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
            RPWQGP            L+RH VRR GGITGDVLG  +E
Sbjct: 203 DRPWQGPLVVAAALATAVWLLRHVVRRLGGITGDVLGATVE 243


>tr|A4XA08|A4XA08_SALTO Tax_Id=369723 SubName:
           Full=Cobalamin-5'-phosphate synthase;
           EC=2.7.8.26;[Salinispora tropica]
          Length = 257

 Score = 92.8 bits (229), Expect = 3e-17
 Identities = 57/161 (35%), Positives = 74/161 (45%), Gaps = 2/161 (1%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADT D LG Y     AL +M+    GPFGVAA+V+++ +Q +  + L        
Sbjct: 83  HLDGLADTVDALGSYRRGPAALEIMKKPDVGPFGVAALVVILLLQAAVLAELAEWSTSTM 142

Query: 138 XXXXXXXXXXXXTAV-LGCRRSVPAAAGSSLGSRVAGT-QPISXXXXXXXXXXXXXXXXX 195
                         V + C R +PAA    LG+ VAGT  P +                 
Sbjct: 143 LTAVVTATAAGRLGVTVACWRGLPAARPDGLGALVAGTVGPGTLAAGTAAVALLALAAVP 202

Query: 196 PRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
            RPWQGP            L+RH VRR GGITGDVLG  +E
Sbjct: 203 DRPWQGPLAVAVALAAAVGLLRHVVRRLGGITGDVLGATVE 243


>tr|D0LAY2|D0LAY2_GORB4 Tax_Id=526226 SubName:
           Full=Cobalamin-5-phosphate synthase CobS; Flags:
           Precursor;[Gordonia bronchialis]
          Length = 261

 Score = 91.3 bits (225), Expect = 9e-17
 Identities = 59/168 (35%), Positives = 70/168 (41%), Gaps = 11/168 (6%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLGCYGPP R   VMR G+ GPFGVA +VLV+ +QG  F  L        
Sbjct: 84  HLDGLADTADGLGCYGPPSRVTEVMRSGTVGPFGVATLVLVLGIQGVGFGALFDQSRWYD 143

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPIS---------XXXXXXXXXX 188
                         ++  RR +  A     G+ VAGTQ  +                   
Sbjct: 144 AAFAVALGRVG--VLVAARRGLAPAHPDGFGALVAGTQRNALVVWAALALAAAAVCGFDV 201

Query: 189 XXXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                  P                 L   HC RR GGITGDVLG  IE
Sbjct: 202 STGVFDLPAAVTAMLVVLVVAVVVWLFTAHCARRMGGITGDVLGATIE 249


>tr|C8XJ12|C8XJ12_NAKMY Tax_Id=479431 SubName:
           Full=Cobalamin-5-phosphate synthase CobS;[Nakamurella
           multipartita]
          Length = 255

 Score = 84.7 bits (208), Expect = 9e-15
 Identities = 56/163 (34%), Positives = 71/163 (43%), Gaps = 5/163 (3%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG      RAL +MR G+ GP GV  +V+V+  Q +A + +        
Sbjct: 82  HLDGLADTADGLGSGYDRTRALEIMRRGNVGPMGVTTLVVVLVAQIAATAAM-LARPGGF 140

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXPR 197
                         +L C R VP A    LG+ VAG  P +                 P 
Sbjct: 141 VLVGVLVCLSRSALLLACARGVPPARPDGLGAMVAGVVPRAGTVAGLLVTAGIAAAVVPI 200

Query: 198 P----WQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                W GP            L+  CVRRFGGITGDV+G  IE
Sbjct: 201 AGSAWWWGPLAVLVAGLAVAGLLTRCVRRFGGITGDVMGATIE 243


>tr|A3TS68|A3TS68_9MICO Tax_Id=313589 SubName: Full=Putative
           cobalamin (5'-phosphate) synthase;[Janibacter sp.
           HTCC2649]
          Length = 224

 Score = 80.5 bits (197), Expect = 2e-13
 Identities = 56/163 (34%), Positives = 76/163 (46%), Gaps = 5/163 (3%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADT DGLG     +RAL VMR G  GP GVAA++LV+  Q +A + +        
Sbjct: 48  HLDGLADTVDGLGAGWTRERALEVMRSGDVGPMGVAALLLVLLAQVAALTAIVDRPQGWL 107

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQP--ISXXXXXXXXXXXXXXXXX 195
                       T +L CR  +P+A    LG+ VAG+ P  ++                 
Sbjct: 108 VAGVAVVASRAST-LLTCRVGMPSARPGGLGAVVAGSVPTWVAGLGGLVVAALLSAAVAA 166

Query: 196 PR--PWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
            R  P  G            +L+R C R FGG+TGDV+G AIE
Sbjct: 167 SRLSPAAGVVAVVLAAVAVGILLRTCRRVFGGVTGDVMGAAIE 209


>tr|C9YTS0|C9YTS0_STRSW Tax_Id=680198 (cobS)SubName: Full=Putative
           cobalamin-5'-phosphate synthase
           (EC:2.7.8.26);[Streptomyces scabies]
          Length = 269

 Score = 79.0 bits (193), Expect = 5e-13
 Identities = 56/165 (33%), Positives = 72/165 (43%), Gaps = 6/165 (3%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG   P + AL +M+    GPFGV  +VLV+  Q +A +          
Sbjct: 92  HLDGLADTADGLGSGKPAEDALRIMKQSDIGPFGVVTLVLVLLAQTAALTGAYGESWALG 151

Query: 138 XXXXXXXXXXXXTAV-LGCRRSVPAAAGSSLGSRVAGTQP--ISXXXXXXXXXXXXXXXX 194
                        A+ L  R  VP A    LG+ VAG  P   +                
Sbjct: 152 ALATAVSATAARLALTLAARAGVPPARPEGLGAAVAGVVPPGSALLVAALVGCAAAGAGA 211

Query: 195 XPRPWQ-GPXXXXXXXXXGT--LLIRHCVRRFGGITGDVLGCAIE 236
              P++ G          G   LL+RHCVRRFGG+TGDV G   E
Sbjct: 212 LSGPYELGRAVLAVVVACGAAELLLRHCVRRFGGVTGDVFGALAE 256


>sp|A1SJN0|COBS_NOCSJ Tax_Id=196162 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Nocardioides sp.]
          Length = 229

 Score = 77.8 bits (190), Expect = 1e-12
 Identities = 54/159 (33%), Positives = 70/159 (44%), Gaps = 21/159 (13%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H D ++DT DGL     P R+LAVMR G++GP GV A V+V  VQ +A +TL        
Sbjct: 79  HWDGLSDTVDGLAASYDPARSLAVMRSGTSGPAGVLATVVVAGVQAAALATLLDQPLLAG 138

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXPR 197
                          + C   VPAA    LG+ VA T P+                    
Sbjct: 139 ALVCLSRCALW----IVCCTRVPAARADGLGADVARTVPLPVAVLG-------------- 180

Query: 198 PWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
              G            +L+R  VRRFGG+TGDV+G A+E
Sbjct: 181 ---GLLLSAVGGLVVLVLVRRTVRRFGGVTGDVMGAAVE 216


>tr|C7MXA3|C7MXA3_SACVD Tax_Id=471857 SubName:
           Full=Cobalamin-5-phosphate synthase;[Saccharomonospora
           viridis]
          Length = 271

 Score = 77.8 bits (190), Expect = 1e-12
 Identities = 54/167 (32%), Positives = 69/167 (41%), Gaps = 8/167 (4%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTL---XXXXX 134
           H+D +ADTADGL       RAL VMR G  GP GV  +VL +  Q +A + +        
Sbjct: 86  HLDGLADTADGLAASYDRDRALDVMRRGDVGPTGVVTLVLAVLTQVAALAGIVASGPTPA 145

Query: 135 XXXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQP-----ISXXXXXXXXXXX 189
                             L C R +P+A    LG+ VAG+ P     +            
Sbjct: 146 TAVSAMAIAVVAGRGMLPLCCVRGLPSARPEGLGAAVAGSVPPGVAAVVAALVIAAAAVV 205

Query: 190 XXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                 P  WQG             L+ H VRRFGG+TGDVLG  +E
Sbjct: 206 TAVVPGPPWWQGVLAVLLGWLAAGALLGHAVRRFGGVTGDVLGACVE 252


>tr|B1VZN6|B1VZN6_STRGG Tax_Id=455632 SubName: Full=Putative
           cobalamin 5'-phosphate synthase;[Streptomyces griseus
           subsp. griseus]
          Length = 260

 Score = 75.9 bits (185), Expect = 4e-12
 Identities = 52/161 (32%), Positives = 69/161 (42%), Gaps = 6/161 (3%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG   P + AL +M+    GPFGV  ++LV+  Q +    L        
Sbjct: 82  HLDGLADTADGLGSGKPAEDALRIMKQSDIGPFGVITLLLVLLAQVAVLFELYGEGWAHG 141

Query: 138 XXXXXXXXXXXXTAVL-GCRRSVPAAAGSSLGSRVAGTQP-----ISXXXXXXXXXXXXX 191
                        A+    R+ VPAA    LG+ VA T P     ++             
Sbjct: 142 AVGAVVAGTAARLALTQASRQGVPAARPEGLGAVVASTVPAGRALLAAVVTVALCAAAGA 201

Query: 192 XXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLG 232
                   +           G LL+RHCVRRFGG+TGDV G
Sbjct: 202 PLGPYGALRHALAALVALAAGELLLRHCVRRFGGVTGDVFG 242


>tr|Q9S2Q9|Q9S2Q9_STRCO Tax_Id=1902 SubName: Full=Putative cobalamin
           (5'-phosphate) synthase;[Streptomyces coelicolor]
          Length = 260

 Score = 75.1 bits (183), Expect = 7e-12
 Identities = 53/167 (31%), Positives = 68/167 (40%), Gaps = 10/167 (5%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG   P + AL +M+    GPFGV A++  +  Q +A +          
Sbjct: 83  HLDGLADTADGLGSGKPAEDALRIMKQSDIGPFGVLALLFTLLAQVAALAQAYDGSWARG 142

Query: 138 XXXXXXXXXXXXTAV-LGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXP 196
                        A+    R  VPAA    LG+ VAG  P                    
Sbjct: 143 ALAAVVSATAARLALTTAARTGVPAARPEGLGAAVAGVVPAGGALAATAAVTLAGAAAG- 201

Query: 197 RPWQGP-------XXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
             + GP                  LL+RHCVRRFGG+TGDV G   E
Sbjct: 202 -AYLGPYDALRTALAVVCAVAVAELLLRHCVRRFGGVTGDVFGGVAE 247


>tr|Q82AN1|Q82AN1_STRAW Tax_Id=33903 (cobS)SubName: Full=Putative
           cobalamin (5'-phosphate) synthase;[Streptomyces
           avermitilis]
          Length = 260

 Score = 73.9 bits (180), Expect = 2e-11
 Identities = 50/161 (31%), Positives = 65/161 (40%), Gaps = 6/161 (3%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFS-TLXXXXXXX 136
           H+D +ADTADGLG   P + AL +M+    GPFGV  +V V+  Q +A +          
Sbjct: 83  HLDGLADTADGLGSGKPAEDALRIMKQSDIGPFGVITLVFVLLAQVAALAQAYETSWARG 142

Query: 137 XXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXP 196
                           L  R  VP A    LG+ VAGT P++                  
Sbjct: 143 AFAAVVSAGAARLVLTLAARTGVPPARPEGLGAAVAGTVPVTGALLTAGAVIAAAAGAGA 202

Query: 197 -----RPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLG 232
                   +             LL+RHC RRFGG+TGDV G
Sbjct: 203 LFGTYDVVRTALAVLLAVAAAELLLRHCTRRFGGVTGDVFG 243


>tr|C1YQE9|C1YQE9_NOCDA Tax_Id=446468 SubName:
           Full=Cobalamin-5'-phosphate synthase;
           EC=2.7.8.26;[Nocardiopsis dassonvillei subsp.
           dassonvillei DSM 43111]
          Length = 252

 Score = 72.0 bits (175), Expect = 6e-11
 Identities = 55/164 (33%), Positives = 66/164 (40%), Gaps = 5/164 (3%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +AD ADGLG   P + AL VMR    GPFGV  +V+V+A Q  A   L        
Sbjct: 72  HLDGLADLADGLGSARPAEGALEVMRRSDIGPFGVVTLVIVLAAQTLALGQLAQASAEAA 131

Query: 138 XXXXXXXXXXXXTAV-LGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXP 196
                        AV L C   VP+A    LG+ VAGT  +                   
Sbjct: 132 LTGAATAGAAGRLAVALACTPRVPSARPEGLGAFVAGTVRLPGALLAAVPAPLVCLAGWA 191

Query: 197 RPWQGPXXXXXXXXXGT----LLIRHCVRRFGGITGDVLGCAIE 236
                          G     LL+R  VRR GG+TGDVLG   E
Sbjct: 192 HAPGFALACALAVAAGLLAAGLLLRRAVRRLGGVTGDVLGALSE 235


>tr|D1A8Z4|D1A8Z4_THECU Tax_Id=471852 SubName:
           Full=Cobalamin-5-phosphate synthase
           CobS;[Thermomonospora curvata DSM 43183]
          Length = 252

 Score = 71.6 bits (174), Expect = 8e-11
 Identities = 49/165 (29%), Positives = 67/165 (40%), Gaps = 10/165 (6%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +AD ADGLG   P   AL +M+    GPFGV AV+L + ++ +A +T         
Sbjct: 78  HLDGLADLADGLGSARPAAEALEIMKRSDIGPFGVVAVLLTLLIRVTALAT----APDAA 133

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQP------ISXXXXXXXXXXXXX 191
                       T    CR  VP A    LG+ VAGT P      ++             
Sbjct: 134 LAAVTAAVAGRLTLPWACRAGVPGARPGGLGALVAGTVPTAAAVAVTVAAAAAAAAAGAA 193

Query: 192 XXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                    G          G + +R  +RR  G+TGDVLG  +E
Sbjct: 194 TGGLEGALHGAGAVAAGLAAGLVTLRRVLRRLHGVTGDVLGALVE 238


>tr|C0UBB7|C0UBB7_9ACTO Tax_Id=526225 SubName:
           Full=Cobalamin-5-phosphate synthase;[Geodermatophilus
           obscurus DSM 43160]
          Length = 245

 Score = 69.7 bits (169), Expect = 3e-10
 Identities = 52/155 (33%), Positives = 65/155 (41%), Gaps = 4/155 (2%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG     +RAL VMR G  GPFGV  ++L + +Q +A +TL        
Sbjct: 76  HLDGLADTADGLGPLRGRERALQVMRQGDVGPFGVVTLLLTVLLQVAAAATLLGAGRGWT 135

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXPR 197
                        A  G    VP AAGS+LG  VAGT                       
Sbjct: 136 ALVAAPLVARLAMARTGL-PGVPMAAGSALGQSVAGTVSARWLAGWVFVAAALLTVADQA 194

Query: 198 PWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLG 232
                           LL+R    R GG+TGDV+G
Sbjct: 195 LL---VSAVAGLLAAELLLRRARARLGGVTGDVMG 226


>tr|C7QD50|C7QD50_CATAD Tax_Id=479433 SubName:
           Full=Cobalamin-5-phosphate synthase CobS;[Catenulispora
           acidiphila]
          Length = 259

 Score = 69.3 bits (168), Expect = 4e-10
 Identities = 52/167 (31%), Positives = 67/167 (40%), Gaps = 8/167 (4%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG   P   AL +M+    GPFGV  +VL +  Q    ++         
Sbjct: 81  HLDGLADTADGLGSAKPAPDALRIMKASDIGPFGVITLVLALLGQVLLLTSAWGRHGAWY 140

Query: 138 XXXXXXXXXXXXTAVL--GCRRSVPAAAGSSLGSRVAGTQP------ISXXXXXXXXXXX 189
                          +   CR  VP+A    LG+ VAG+         S           
Sbjct: 141 GACAIAVSCVAGRLAVPWACRPGVPSARPDGLGAWVAGSVSQVAVAIASTGALVAATIAG 200

Query: 190 XXXXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                  R    P          TL++RH  RRFGGITGDVLG  +E
Sbjct: 201 LCVTDGARWLLWPAAIVAAIGSATLVLRHTNRRFGGITGDVLGALVE 247


>tr|Q47R83|Q47R83_THEFY Tax_Id=269800 SubName:
           Full=Cobalamin-5'-phosphate synthase;
           EC=2.7.8.26;[Thermobifida fusca]
          Length = 253

 Score = 66.6 bits (161), Expect = 2e-09
 Identities = 52/160 (32%), Positives = 64/160 (40%), Gaps = 5/160 (3%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H D +AD ADGLG      RALAVM+    GPFGV  +V V+ +Q +A + L        
Sbjct: 85  HWDGLADVADGLGSGADADRALAVMKRSDIGPFGVITLVFVVLLQVAAVAALAEEGTGAA 144

Query: 138 XXXXXXXXXXXXTAVL-GCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXP 196
                        A+   C R V AA    LG+ V+GT P                    
Sbjct: 145 VAGLAAALVSGRLAITWACTRLVGAARPEGLGAFVSGTVPYPAAAAVTCVVLAVGLVEW- 203

Query: 197 RPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
             W            G L+     RR GGITGDVLG  +E
Sbjct: 204 -TWCAAVAAGLVVAGGVLV--WVCRRLGGITGDVLGALVE 240


>tr|B5GV05|B5GV05_STRCL Tax_Id=443255 SubName: Full=Cobalamin
           synthase;[Streptomyces clavuligerus ATCC 27064]
          Length = 264

 Score = 66.6 bits (161), Expect = 2e-09
 Identities = 50/160 (31%), Positives = 64/160 (40%), Gaps = 8/160 (5%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG   P   ALAV +    GPFGV  ++  +  Q +A + L        
Sbjct: 78  HLDGLADTADGLGSARPAAGALAVKKRSDIGPFGVITLLFTLFAQVAALAELYGRGWAHG 137

Query: 138 XXXXXXXXXXXXTAV-LGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXP 196
                        A+ +  R  VPAA    LG+ VA   P+                   
Sbjct: 138 ALGALLAAVTARLALTVASRTGVPAARPEGLGAAVAEVLPVRTAWSAAALVVLAGAGLGT 197

Query: 197 RPWQGP------XXXXXXXXXGTLLIRHCVRRFGGITGDV 230
            P  GP                 LL+RHCVRRFGG+ G V
Sbjct: 198 AP-GGPGALRYGLAAVLGLIAAGLLLRHCVRRFGGVNGHV 236


>tr|B4V3K8|B4V3K8_9ACTO Tax_Id=465541 SubName: Full=Cobalamin
           synthase;[Streptomyces sp. Mg1]
          Length = 203

 Score = 65.9 bits (159), Expect = 4e-09
 Identities = 36/100 (36%), Positives = 51/100 (51%), Gaps = 1/100 (1%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG   P + AL +M+    GPFGV  ++LV+ +Q +A + +        
Sbjct: 96  HLDGLADTADGLGSAKPAEDALRIMKQSDIGPFGVVTLLLVLLIQAAALADVYADSWVRG 155

Query: 138 XXXXXXXXXXXXTAV-LGCRRSVPAAAGSSLGSRVAGTQP 176
                        A+ L CR  VPAA    LG+ +AG  P
Sbjct: 156 ALAAVLAAVTARLALTLACRDGVPAARPEGLGATIAGGLP 195


>tr|A8LFB8|A8LFB8_FRASN Tax_Id=298653 SubName: Full=Cobalamin
           5'-phosphate synthase;[Frankia sp.]
          Length = 275

 Score = 65.5 bits (158), Expect = 5e-09
 Identities = 51/168 (30%), Positives = 64/168 (38%), Gaps = 10/168 (5%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +AD  D  G  G  +RALAVMR+ + G FG   V+ V+ VQ SA S +        
Sbjct: 84  HLDGLADVGDAFGVRGGRERALAVMRESTIGAFGAITVLFVVLVQVSALS-IAITAHRGT 142

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGTQPISXXXXXXXXXXXXXXXXXPR 197
                        A L C   +P+A    LG+ VAG+                       
Sbjct: 143 VSILVAAMAGRLAATLSCVEGIPSARPDGLGALVAGSVRRRDAVLATVGVLVVAGLAGRL 202

Query: 198 PWQGP---------XXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
            + G                      L R  VRRFGGITGD LG  IE
Sbjct: 203 DYDGGDTGRAVRAIIAVAVGVAVSIALRRWLVRRFGGITGDTLGATIE 250


>sp|Q2J8A4|COBS_FRASC Tax_Id=106370 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Frankia sp.]
          Length = 278

 Score = 60.1 bits (144), Expect = 2e-07
 Identities = 51/170 (30%), Positives = 68/170 (40%), Gaps = 12/170 (7%)

Query: 78  HIDAVADTADGLGCYGPP--QRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXX 135
           H+D +AD  DGLG +      RAL +MR+ + G FG   V+ V+ +Q  A ST       
Sbjct: 85  HLDGLADLGDGLGAWRARGRDRALEIMRESTIGAFGAIIVLFVVLLQVGALST-TISAHR 143

Query: 136 XXXXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAGT--------QPISXXXXXXXXX 187
                          A L C  +VP A    LG+ VAGT          ++         
Sbjct: 144 GTLSILVAAMTSRLAATLACTGAVPPARPDGLGALVAGTVRTRDAALSFLAVCAVAALAG 203

Query: 188 XXXXXXXXP-RPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                   P R  +             LL R+ + RFGGITGD+LG  IE
Sbjct: 204 LLDFDGGGPGRALRAVLAVWVGTGVSFLLRRYLLTRFGGITGDILGGLIE 253


>tr|Q75NF3|Q75NF3_PROFR Tax_Id=1752 (cobS)SubName: Full=Cobalamin
           5'-phosphate synthase;[Propionibacterium freudenreichii
           subsp. shermanii]
          Length = 259

 Score = 59.7 bits (143), Expect = 3e-07
 Identities = 45/165 (27%), Positives = 63/165 (38%), Gaps = 6/165 (3%)

Query: 78  HIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLXXXXXXXX 137
           H+D +ADTADGLG   P   AL +MR    GP GV A++LV+A++ +A  +         
Sbjct: 81  HLDGLADTADGLGSRKPAHEALTIMRQSDIGPMGVTAIILVLALEIAAGGSGHLDGWRGV 140

Query: 138 XXXXXXXXXXXXTAVLGCRRSVPAAAGSSLGSRVAG-TQP-----ISXXXXXXXXXXXXX 191
                       +A+    R +P+A     G+  AG T P      S             
Sbjct: 141 WLLVTMPMVARVSALSATGRWIPSAHKKGFGALFAGKTHPATIVVASVIAAVIAAGSGWL 200

Query: 192 XXXXPRPWQGPXXXXXXXXXGTLLIRHCVRRFGGITGDVLGCAIE 236
                               G    RH + R GG+TGD  G  +E
Sbjct: 201 LFGWRAALVAVCACLASWVFGVAWRRHILARLGGLTGDTFGSLVE 245


  Database: Amellifera_nr
    Posted date:  Feb 5, 2010  5:10 AM
  Number of letters in database: 3,846,993,858
  Number of sequences in database:  11,275,203
  
Lambda     K      H
   0.323    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11275203
Number of Hits to DB: 1,068,246,245
Number of extensions: 26093520
Number of successful extensions: 43786
Number of sequences better than 10.0: 676
Number of HSP's gapped: 43658
Number of HSP's successfully gapped: 684
Length of query: 252
Length of database: 3,846,993,858
Length adjustment: 134
Effective length of query: 118
Effective length of database: 2,336,116,656
Effective search space: 275661765408
Effective search space used: 275661765408
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 79 (35.0 bits)