BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_3491 (413 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HJW8|B2HJW8_MYCMM Tax_Id=216594 SubName: Full=Pyruvate dehy... 634 e-180 tr|Q1BD28|Q1BD28_MYCSS Tax_Id=164756 SubName: Full=Catalytic dom... 491 e-137 tr|A3PVJ9|A3PVJ9_MYCSJ Tax_Id=164757 SubName: Full=Catalytic dom... 491 e-137 tr|A1UBW5|A1UBW5_MYCSK Tax_Id=189918 SubName: Full=Catalytic dom... 491 e-137 tr|A1T4Z4|A1T4Z4_MYCVP Tax_Id=350058 SubName: Full=Catalytic dom... 406 e-111 tr|Q12FH2|Q12FH2_POLSJ Tax_Id=296591 SubName: Full=Catalytic dom... 371 e-100 tr|B9Z0W1|B9Z0W1_9NEIS Tax_Id=279714 SubName: Full=Catalytic dom... 368 e-100 tr|C4ZNL1|C4ZNL1_THASP Tax_Id=85643 SubName: Full=Dihydrolipoyll... 368 e-100 tr|Q222B4|Q222B4_RHOFD Tax_Id=338969 SubName: Full=Catalytic dom... 362 4e-98 tr|Q2T6S2|Q2T6S2_BURTA Tax_Id=271848 SubName: Full=Probable pyru... 358 9e-97 tr|C6BL73|C6BL73_RALP1 Tax_Id=428406 SubName: Full=Catalytic dom... 355 4e-96 tr|B2UJI1|B2UJI1_RALPJ Tax_Id=402626 SubName: Full=Catalytic dom... 355 4e-96 tr|B2JTY4|B2JTY4_BURP8 Tax_Id=391038 SubName: Full=Catalytic dom... 345 6e-93 tr|A5GEF2|A5GEF2_GEOUR Tax_Id=351605 SubName: Full=Catalytic dom... 308 6e-82 tr|Q6ALF2|Q6ALF2_DESPS Tax_Id=84980 (phdC)SubName: Full=Probable... 300 2e-79 tr|Q6AIE3|Q6AIE3_DESPS Tax_Id=84980 SubName: Full=Probable pyruv... 295 7e-78 tr|C4DDQ6|C4DDQ6_9ACTO Tax_Id=446470 SubName: Full=Pyruvate/2-ox... 282 5e-74 tr|A8FVB3|A8FVB3_SHESH Tax_Id=425104 SubName: Full=Catalytic dom... 244 2e-62 tr|A6Q8W6|A6Q8W6_SULNB Tax_Id=387093 SubName: Full=Pyruvate/2-ox... 240 3e-61 tr|B4UXF3|B4UXF3_9ACTO Tax_Id=465541 SubName: Full=Putative unch... 231 1e-58 tr|A0JS87|A0JS87_ARTS2 Tax_Id=290399 SubName: Full=Catalytic dom... 227 2e-57 tr|Q0A5F2|Q0A5F2_ALHEH Tax_Id=187272 SubName: Full=Catalytic dom... 220 3e-55 tr|A4FCC8|A4FCC8_SACEN Tax_Id=405948 SubName: Full=Probable pyru... 202 6e-50 tr|A3JZ33|A3JZ33_9RHOB Tax_Id=388399 SubName: Full=Dihydrolipoam... 170 3e-40 tr|Q1D8Y6|Q1D8Y6_MYXXD Tax_Id=246197 (pdhC)SubName: Full=Pyruvat... 168 1e-39 tr|A8LQM9|A8LQM9_DINSH Tax_Id=398580 (pdhC1)SubName: Full=Dihydr... 168 1e-39 tr|Q164R3|Q164R3_ROSDO Tax_Id=375451 (pdhC)SubName: Full=Pyruvat... 167 2e-39 tr|B9QS00|B9QS00_9RHOB Tax_Id=244592 SubName: Full=Pyruvate dehy... 164 1e-38 tr|Q0BSW9|Q0BSW9_GRABC Tax_Id=391165 SubName: Full=Dihydrolipoam... 163 3e-38 tr|D0CY56|D0CY56_9RHOB Tax_Id=644107 SubName: Full=Pyruvate dehy... 163 4e-38 tr|A8GXH9|A8GXH9_RICB8 Tax_Id=391896 SubName: Full=Branched-chai... 162 6e-38 tr|A4TXZ0|A4TXZ0_9PROT Tax_Id=55518 (pdhC)SubName: Full=Dihydrol... 162 1e-37 tr|B6AW84|B6AW84_9RHOB Tax_Id=314270 SubName: Full=Pyruvate dehy... 161 1e-37 tr|Q28RQ7|Q28RQ7_JANSC Tax_Id=290400 SubName: Full=Dihydrolipoam... 161 2e-37 tr|Q1GTS2|Q1GTS2_SPHAL Tax_Id=117207 SubName: Full=Dihydrolipoam... 161 2e-37 sp|Q1RJT3|ODP2_RICBR Tax_Id=336407 (pdhC)RecName: Full=Dihydroli... 160 2e-37 tr|A8TL71|A8TL71_9PROT Tax_Id=331869 SubName: Full=Pyruvate/2-ox... 160 4e-37 sp|Q4ULG1|ODP2_RICFE Tax_Id=42862 (pdhC)RecName: Full=Dihydrolip... 159 6e-37 tr|C1YP51|C1YP51_NOCDA Tax_Id=446468 SubName: Full=Pyruvate/2-ox... 159 8e-37 tr|A8F1S0|A8F1S0_RICM5 Tax_Id=416276 (pdhC)SubName: Full=Pyruvat... 158 1e-36 tr|Q47KD8|Q47KD8_THEFY Tax_Id=269800 SubName: Full=Pyruvate dehy... 158 1e-36 tr|C4K0D0|C4K0D0_RICPU Tax_Id=562019 SubName: Full=Branched-chai... 157 2e-36 tr|B5KBW7|B5KBW7_9RHOB Tax_Id=391616 SubName: Full=Pyruvate dehy... 157 2e-36 tr|Q3J3J1|Q3J3J1_RHOS4 Tax_Id=272943 (pdhB)SubName: Full=Dihydro... 157 2e-36 tr|A3PIU1|A3PIU1_RHOS1 Tax_Id=349101 SubName: Full=Pyruvate dehy... 157 2e-36 tr|B0BXT8|B0BXT8_RICRO Tax_Id=452659 SubName: Full=Dihydrolipoam... 157 3e-36 tr|A8GSC6|A8GSC6_RICRS Tax_Id=392021 SubName: Full=Branched-chai... 157 3e-36 tr|C3PNM9|C3PNM9_RICAE Tax_Id=347255 (pdhC)SubName: Full=Pyruvat... 156 4e-36 tr|B9KQT2|B9KQT2_RHOSK Tax_Id=557760 SubName: Full=Pyruvate dehy... 156 4e-36 tr|A8GNQ3|A8GNQ3_RICAH Tax_Id=293614 SubName: Full=Branched-chai... 156 4e-36 >tr|B2HJW8|B2HJW8_MYCMM Tax_Id=216594 SubName: Full=Pyruvate dehydrogenase (E2 component);[Mycobacterium marinum] Length = 413 Score = 634 bits (1634), Expect = e-180 Identities = 336/413 (81%), Positives = 336/413 (81%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV Sbjct: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRW 120 PVGDTVEVGTVLATLLEPGA KR RHRRW Sbjct: 61 PVGDTVEVGTVLATLLEPGASPQRSPRQRPRKRATPAPTVAASAPAPAHGATAAPRHRRW 120 Query: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXX 180 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEH Sbjct: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHAAASAVPAKRPAATAASTSAKSIGA 180 Query: 181 XXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER 240 QNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER Sbjct: 181 KSTAQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER 240 Query: 241 XXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK 300 QRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK Sbjct: 241 VLPAVLLLKAVGLAAQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK 300 Query: 301 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK 360 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK Sbjct: 301 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK 360 Query: 361 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK Sbjct: 361 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 >tr|Q1BD28|Q1BD28_MYCSS Tax_Id=164756 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Mycobacterium sp.] Length = 399 Score = 491 bits (1264), Expect = e-137 Identities = 260/418 (62%), Positives = 288/418 (68%), Gaps = 24/418 (5%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EF+MPALGSDMDEGTL++WLVKPGD V+RGQ+VA+VETTKAAVE+ECWQEGTVD L+V Sbjct: 1 MTEFRMPALGSDMDEGTLDQWLVKPGDTVTRGQVVAVVETTKAAVEVECWQEGTVDRLLV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXR---- 116 P G TV VGT LATLL PG Sbjct: 61 PEGQTVRVGTPLATLLAPGETPAPTAPAVPRTMRESPVAVERPEGAGRPAPAAGPAIATR 120 Query: 117 -HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXX 175 HRRWVSPAARR+A +L +D D ++GTGPQGAVTI DVE Sbjct: 121 PHRRWVSPAARRVAATLDIDADTLTGTGPQGAVTIRDVEQAAASRKQPADG--------- 171 Query: 176 XXXXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQR 235 + +R+ MR SIAAAMSRSKREIPHYYLADE+LM+ +L WL RNA R Sbjct: 172 ----------RTVRDRSVAMRASIAAAMSRSKREIPHYYLADEVLMDPALAWLAERNAAR 221 Query: 236 SITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIH 295 SITER RF EFNGFWRDD F A GVHVGV ISLRGGGLVAPAIH Sbjct: 222 SITERVLPAVLQIKAVAAAADRFPEFNGFWRDDAFVGADGVHVGVAISLRGGGLVAPAIH 281 Query: 296 DVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAI 355 DV D+ LD+LMG LTDLVARARAGSLRSSEMSDP+IT+TNLGDQGVDTVFGVIYPPQVA+ Sbjct: 282 DVPDRSLDDLMGALTDLVARARAGSLRSSEMSDPSITITNLGDQGVDTVFGVIYPPQVAL 341 Query: 356 VGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 VGFGKP QRVC +DGGIR+ T + TLAADHRASDGHRGALFLAAINE+LQQP LEK Sbjct: 342 VGFGKPVQRVCAVDGGIRIATALTATLAADHRASDGHRGALFLAAINEILQQPQKLEK 399 >tr|A3PVJ9|A3PVJ9_MYCSJ Tax_Id=164757 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Mycobacterium sp.] Length = 399 Score = 491 bits (1264), Expect = e-137 Identities = 260/418 (62%), Positives = 288/418 (68%), Gaps = 24/418 (5%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EF+MPALGSDMDEGTL++WLVKPGD V+RGQ+VA+VETTKAAVE+ECWQEGTVD L+V Sbjct: 1 MTEFRMPALGSDMDEGTLDQWLVKPGDTVTRGQVVAVVETTKAAVEVECWQEGTVDRLLV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXR---- 116 P G TV VGT LATLL PG Sbjct: 61 PEGQTVRVGTPLATLLAPGETPAPTAPAVPRTMRESPVAVERPEGAGRPAPAAGPAIATR 120 Query: 117 -HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXX 175 HRRWVSPAARR+A +L +D D ++GTGPQGAVTI DVE Sbjct: 121 PHRRWVSPAARRVAATLDIDADTLTGTGPQGAVTIRDVEQAAASRKQPADG--------- 171 Query: 176 XXXXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQR 235 + +R+ MR SIAAAMSRSKREIPHYYLADE+LM+ +L WL RNA R Sbjct: 172 ----------RTVRDRSVAMRASIAAAMSRSKREIPHYYLADEVLMDPALAWLAERNAAR 221 Query: 236 SITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIH 295 SITER RF EFNGFWRDD F A GVHVGV ISLRGGGLVAPAIH Sbjct: 222 SITERVLPAVLQIKAVAAAADRFPEFNGFWRDDAFVGADGVHVGVAISLRGGGLVAPAIH 281 Query: 296 DVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAI 355 DV D+ LD+LMG LTDLVARARAGSLRSSEMSDP+IT+TNLGDQGVDTVFGVIYPPQVA+ Sbjct: 282 DVPDRSLDDLMGALTDLVARARAGSLRSSEMSDPSITITNLGDQGVDTVFGVIYPPQVAL 341 Query: 356 VGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 VGFGKP QRVC +DGGIR+ T + TLAADHRASDGHRGALFLAAINE+LQQP LEK Sbjct: 342 VGFGKPVQRVCAVDGGIRIATALTATLAADHRASDGHRGALFLAAINEILQQPQKLEK 399 >tr|A1UBW5|A1UBW5_MYCSK Tax_Id=189918 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Mycobacterium sp.] Length = 399 Score = 491 bits (1264), Expect = e-137 Identities = 260/418 (62%), Positives = 288/418 (68%), Gaps = 24/418 (5%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EF+MPALGSDMDEGTL++WLVKPGD V+RGQ+VA+VETTKAAVE+ECWQEGTVD L+V Sbjct: 1 MTEFRMPALGSDMDEGTLDQWLVKPGDTVTRGQVVAVVETTKAAVEVECWQEGTVDRLLV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXR---- 116 P G TV VGT LATLL PG Sbjct: 61 PEGQTVRVGTPLATLLAPGETPAPTAPAVPRTMRESPVAVERPEGAGRPAPAAGPAIATR 120 Query: 117 -HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXX 175 HRRWVSPAARR+A +L +D D ++GTGPQGAVTI DVE Sbjct: 121 PHRRWVSPAARRVAATLDIDADTLTGTGPQGAVTIRDVEQAAASRKQPADG--------- 171 Query: 176 XXXXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQR 235 + +R+ MR SIAAAMSRSKREIPHYYLADE+LM+ +L WL RNA R Sbjct: 172 ----------RTVRDRSVAMRASIAAAMSRSKREIPHYYLADEVLMDPALAWLAERNAAR 221 Query: 236 SITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIH 295 SITER RF EFNGFWRDD F A GVHVGV ISLRGGGLVAPAIH Sbjct: 222 SITERVLPAVLQIKAVAAAADRFPEFNGFWRDDAFVGADGVHVGVAISLRGGGLVAPAIH 281 Query: 296 DVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAI 355 DV D+ LD+LMG LTDLVARARAGSLRSSEMSDP+IT+TNLGDQGVDTVFGVIYPPQVA+ Sbjct: 282 DVPDRSLDDLMGALTDLVARARAGSLRSSEMSDPSITITNLGDQGVDTVFGVIYPPQVAL 341 Query: 356 VGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 VGFGKP QRVC +DGGIR+ T + TLAADHRASDGHRGALFLAAINE+LQQP LEK Sbjct: 342 VGFGKPVQRVCAVDGGIRIATALTATLAADHRASDGHRGALFLAAINEILQQPQKLEK 399 >tr|A1T4Z4|A1T4Z4_MYCVP Tax_Id=350058 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Mycobacterium vanbaalenii] Length = 447 Score = 406 bits (1044), Expect = e-111 Identities = 245/455 (53%), Positives = 269/455 (59%), Gaps = 50/455 (10%) Query: 1 MIEFKMPALGSDMDEG-------------------------------------TLNEWLV 23 MIEF MPALGSDMDEG T++E LV Sbjct: 1 MIEFAMPALGSDMDEGMLNEWLVKPGDTVSRGQVVAVVETTKAAVEIECWHDGTVHELLV 60 Query: 24 KPGDKVSRGQIVA-IVETTKAAVEIECWQEGTVDELVVPVGDTVEVGTVLATLLEPG--- 79 G VS G +A ++E+ + A E P V + + PG Sbjct: 61 PVGQTVSVGTPLATLLESGEVAAEHPA--VSPKQPAAAPSEQPAAVSSEQPAAVAPGRPA 118 Query: 80 AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRWVSPAARRLAQSLHVDLDAV 139 A R HRRWVSPAARRLA SLHVDLDAV Sbjct: 119 AVSSGRPAAVSSGRPAAVSSGRPAAVSSGRPAAVPSGHRRWVSPAARRLASSLHVDLDAV 178 Query: 140 SGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQNKIAE-RAAQMRKS 198 +GTGPQGAVTI+DVEH K AE R A MR+S Sbjct: 179 TGTGPQGAVTITDVEHAAAEAAGSAAETARPAAETAGPAAA------KPAESRGAMMRRS 232 Query: 199 IAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITERXXXXXXXXXXXXXXXQRF 258 IAAAM RSKREIPHYYLA+EIL++ S WL RNAQRSITER QRF Sbjct: 233 IAAAMGRSKREIPHYYLANEILLDASSQWLAERNAQRSITERVLPAALLLKAVGVAAQRF 292 Query: 259 GEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARA 318 E NGFWRDDGF A VHVGVGISLRGGGLVAPAIHDV KKLDE+M +LTDLVARARA Sbjct: 293 QELNGFWRDDGFVPADAVHVGVGISLRGGGLVAPAIHDVPGKKLDEVMSELTDLVARARA 352 Query: 319 GSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTV 378 GSLRSSEMSDPTITVTNLGDQGVDTVFG+IYPPQVA+VGFGKPAQRVC +DGGIR+ TTV Sbjct: 353 GSLRSSEMSDPTITVTNLGDQGVDTVFGIIYPPQVALVGFGKPAQRVCAVDGGIRIATTV 412 Query: 379 QGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 TLAADHRASDGHRGA+FLAAI++LLQQPD LEK Sbjct: 413 HATLAADHRASDGHRGAMFLAAIDQLLQQPDQLEK 447 >tr|Q12FH2|Q12FH2_POLSJ Tax_Id=296591 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Polaromonas sp.] Length = 420 Score = 371 bits (952), Expect = e-100 Identities = 211/421 (50%), Positives = 254/421 (60%), Gaps = 29/421 (6%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 MIEFK+PALG+DMDEGTL +W V+PGD V RGQ+VA+V+T+KAAV++E WQ+G + EL V Sbjct: 1 MIEFKLPALGADMDEGTLLKWHVQPGDAVKRGQVVAVVDTSKAAVDVEIWQDGVMTELRV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXR---- 116 G+ V VGTVLA LL PG R Sbjct: 61 QPGEKVPVGTVLARLLAPGEVAAPAATSLTASTVPTVPVAVPQSVPAAPPQPALPRVPEI 120 Query: 117 ------HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 R VSP+ARR A+ +D D+V GTGPQG+VT++D+E Sbjct: 121 EKALPAARHPVSPSARRHAREHGIDPDSVHGTGPQGSVTLADIEAAVAARRPPLPVAAAP 180 Query: 171 XXXXXXXXXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTT 230 +R +MRK+IAA MSRSKREIPHYYL++ I M ++L WL Sbjct: 181 -------------------DRQTEMRKAIAATMSRSKREIPHYYLSEPIPMARALAWLLQ 221 Query: 231 RNAQRSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLV 290 RN ITER QR + NG +RD FQ +T VH GV ISLRGGGLV Sbjct: 222 RNEGLPITERILPAVLQLKAVAAALQRVPQLNGLYRDGAFQLSTAVHAGVAISLRGGGLV 281 Query: 291 APAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYP 350 APAIHDV K L+ LM +L DLV RARAGSLRSSEMSDPTIT+TNLGDQGV+ VFGVIYP Sbjct: 282 APAIHDVGAKPLELLMRELADLVKRARAGSLRSSEMSDPTITITNLGDQGVEAVFGVIYP 341 Query: 351 PQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDL 410 PQVA+VGFG+ A V +G +R + V TLAADHR SDGH+GALFLA + +LLQQP Sbjct: 342 PQVALVGFGRVADGPWVEEGEVRALPLVTATLAADHRVSDGHQGALFLAELRDLLQQPQA 401 Query: 411 L 411 L Sbjct: 402 L 402 >tr|B9Z0W1|B9Z0W1_9NEIS Tax_Id=279714 SubName: Full=Catalytic domain of component of various dehydrogenase complexes;[Lutiella nitroferrum 2002] Length = 363 Score = 368 bits (945), Expect = e-100 Identities = 205/411 (49%), Positives = 253/411 (61%), Gaps = 48/411 (11%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 MIEFK+P+LG+DMDEG L EW + PGD V RG IVAIV+T KAAV++E W +GTV +L++ Sbjct: 1 MIEFKLPSLGADMDEGKLLEWKIHPGDTVKRGDIVAIVDTAKAAVDVESWVDGTVRQLLI 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRW 120 +GD V VGT +A LL PG RR Sbjct: 61 DIGDKVPVGTPIALLLAPGETAENAVLPARGAE------------------------RRR 96 Query: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXX 180 +SPAAR+ A L VDL ++SG+G +GA+T+ DVE Sbjct: 97 ISPAARKRAGELGVDLASLSGSGAEGAITLQDVE------------------------AK 132 Query: 181 XXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER 240 +R A+MR++IAAAMSRSKREIPHYYLAD I + +L WL RNA+ +TER Sbjct: 133 AVATATPAPDRGAEMRRAIAAAMSRSKREIPHYYLADTIPLRPALAWLERRNAELPVTER 192 Query: 241 XXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK 300 +R+ E NG W D F AA H+GV ISLR GGL+APA+HDVA K Sbjct: 193 LLPAVLLLKAVALATRRYPEMNGHWIDGAFHAAPAAHLGVAISLRQGGLIAPALHDVAAK 252 Query: 301 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK 360 L+ LM +LTDLV RARAGSLRSSEM+DPT+TVTNLG+QG ++VFGVIYPPQVA+VGFGK Sbjct: 253 PLEVLMHELTDLVQRARAGSLRSSEMADPTLTVTNLGEQGSESVFGVIYPPQVALVGFGK 312 Query: 361 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 +R V G + +V +L+ DHRASDGHRGALFLA I +LLQQPD L Sbjct: 313 VMERPWVEQGQCVAMPSVIASLSGDHRASDGHRGALFLAEIRQLLQQPDAL 363 >tr|C4ZNL1|C4ZNL1_THASP Tax_Id=85643 SubName: Full=Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; EC=2.3.1.168;[Thauera sp.] Length = 404 Score = 368 bits (944), Expect = e-100 Identities = 211/416 (50%), Positives = 260/416 (62%), Gaps = 17/416 (4%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EFK+P+LG+DMDEG L EWLV+PGD+V +GQ+VAIV+T+KAAV++E WQ+GTV EL+V Sbjct: 1 MFEFKLPSLGADMDEGKLLEWLVRPGDRVVKGQVVAIVDTSKAAVDVEIWQDGTVHELLV 60 Query: 61 PVGDTVEVGTVLATLLEPG---AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRH 117 G + VGTV+ATLLEPG A Sbjct: 61 EPGTRMAVGTVMATLLEPGEAPAAKRTRTKTVKAAAAAAVPVVEAPAAKPAPDVSPAPAG 120 Query: 118 RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXX 177 R VSPAAR+ A++L V+L A+SG+GP GAVT+ DVE Sbjct: 121 RLRVSPAARKRAEALGVELAALSGSGPGGAVTLEDVERAVAVARLPASPPAATPSPI--- 177 Query: 178 XXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSI 237 AER A+ R++IAAAMSRSKREIPHYYL + + M ++ +WL NA R I Sbjct: 178 ---------SAAERQAETRRAIAAAMSRSKREIPHYYLFETVPMARAQDWLGRANAGRPI 228 Query: 238 TERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDV 297 TER +++ E NGF RD F AA G+HVGV ISLR GGL+APA+HDV Sbjct: 229 TERLLMAVLQLKAVALALRKYPELNGFHRDGQFVAAQGIHVGVAISLRQGGLIAPALHDV 288 Query: 298 ADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVG 357 K LD LM +L DLV R RAGSLRSSEM DPT+TVTNLG+QGV+ V GVIYPPQVA+VG Sbjct: 289 DHKPLDVLMRELADLVRRTRAGSLRSSEMGDPTVTVTNLGEQGVEAVAGVIYPPQVALVG 348 Query: 358 FGKPAQRVCVID--GGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 FG+ A R V + G + V+ V +LAADHR SDGHRGALFLA + ELLQ+P+ L Sbjct: 349 FGRIALRPWVREDRGELCVMPVVTASLAADHRVSDGHRGALFLAELRELLQRPEEL 404 >tr|Q222B4|Q222B4_RHOFD Tax_Id=338969 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Rhodoferax ferrireducens] Length = 417 Score = 362 bits (930), Expect = 4e-98 Identities = 209/418 (50%), Positives = 250/418 (59%), Gaps = 23/418 (5%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 MIEFK+P+LG+DMDEGTL EW +KPGD V RGQ+VA+V+T+KAAV++E W +G V EL V Sbjct: 1 MIEFKLPSLGADMDEGTLLEWHIKPGDVVKRGQVVAVVDTSKAAVDVEIWHDGVVHELRV 60 Query: 61 PVGDTVEVGTVLATLLEPG-------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXX 113 VG+ V V TVLATLL PG A Sbjct: 61 AVGEKVPVDTVLATLLAPGEVAAAPAAASAAAPEPRAAAAAAPVARPAPATQRALEPDQL 120 Query: 114 XXRHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXX 173 R SPAARR A+ L +D D V GTG QG+VT++D+E Sbjct: 121 PATTRHPASPAARRRAKELGMDPDTVPGTGAQGSVTLADIEAAAHAAPAPGAAPSPALA- 179 Query: 174 XXXXXXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNA 233 ++R MRK+IAAAMSRSKREIPHYYL++ I M ++L+WL RN Sbjct: 180 ---------------SDRQKAMRKAIAAAMSRSKREIPHYYLSETIPMTRALDWLRQRNE 224 Query: 234 QRSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPA 293 +TER QR E NGF+RD F+ + VH GV ISLRGGGLVAPA Sbjct: 225 GLPMTERILTAALLLKAVAAALQRTPELNGFYRDGQFEPSVAVHAGVAISLRGGGLVAPA 284 Query: 294 IHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQV 353 +HDV K L +LM +L DLV RARAGSLRSSEM DPTIT+TNLG+Q V +VFGVIYPPQV Sbjct: 285 LHDVGAKPLAQLMRELADLVKRARAGSLRSSEMMDPTITITNLGEQSVQSVFGVIYPPQV 344 Query: 354 AIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 A+VG G A R V G + + + TLAADHRASDGHRGALFLA + ELLQQP L Sbjct: 345 ALVGLGGIAVRPWVEGGKVHALPLLCATLAADHRASDGHRGALFLAELRELLQQPQTL 402 >tr|Q2T6S2|Q2T6S2_BURTA Tax_Id=271848 SubName: Full=Probable pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase;[Burkholderia thailandensis] Length = 379 Score = 358 bits (918), Expect = 9e-97 Identities = 197/413 (47%), Positives = 251/413 (60%), Gaps = 34/413 (8%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 MIEF +P++G+DMDEGTL EW VKPGD V +GQ+VA+V+T+KAAV+IE WQEGTVDEL+V Sbjct: 1 MIEFTLPSMGADMDEGTLLEWKVKPGDAVKKGQVVAVVDTSKAAVDIESWQEGTVDELIV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRW 120 G+ + VGT +ATLLEPG R RR Sbjct: 61 EPGEKIPVGTPIATLLEPGETPPAVRPVRRRARPAAAVGAGA---------------RRK 105 Query: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXX 180 +SPAAR+ A VDLDAVSGTGP G+VT++DVE Sbjct: 106 ISPAARQRAMRGGVDLDAVSGTGPGGSVTLADVERTSAAAAAPSEAAAT----------- 154 Query: 181 XXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER 240 +RA +MR+ IAAAM+RSK EIPHYY+++ I + K+L WL NA+RS+ +R Sbjct: 155 --------GDRAREMRRVIAAAMARSKHEIPHYYVSEPIPLGKALAWLAAENAKRSVVDR 206 Query: 241 XXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK 300 RF E NGF+R FQ A VH+GV ISLR GGL+APA+ D K Sbjct: 207 LLPAALLLKAVAVTLTRFPELNGFYRQGAFQPAGQVHLGVAISLRQGGLIAPALLDAGTK 266 Query: 301 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK 360 L +LM +L DL R+RAGSLRS+E+S TITVTNLGD+G VFG+IYPPQVA+VGFG+ Sbjct: 267 PLTQLMRELADLTQRSRAGSLRSAELSQSTITVTNLGDRGAAEVFGIIYPPQVALVGFGR 326 Query: 361 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 +R G + V+ V +++ADHR SDGHRGALFL ++E LQ P+ L + Sbjct: 327 IVERPWAEGGALGVMPVVTASVSADHRVSDGHRGALFLVELSEALQNPEALSR 379 >tr|C6BL73|C6BL73_RALP1 Tax_Id=428406 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Ralstonia pickettii] Length = 375 Score = 355 bits (912), Expect = 4e-96 Identities = 193/413 (46%), Positives = 255/413 (61%), Gaps = 38/413 (9%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 MI F++PALG+DMDEGTL EW VKPGD V +GQI+A+V+T+KAA+++E W EGTV EL+V Sbjct: 1 MIAFRLPALGADMDEGTLLEWQVKPGDTVKKGQIIAVVDTSKAAIDVESWHEGTVAELLV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRW 120 G + VGT +A LEPG KR + RR Sbjct: 61 TPGTKIPVGTPMAMFLEPGEAPGAV------KRQPDMPGAARPLPPP--------QTRRM 106 Query: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXX 180 SPAAR+ A+ +D+D ++GTG G +T++DVEH Sbjct: 107 ASPAARQAARERGIDIDTITGTGHGGVITLADVEHATPVGSAVT---------------- 150 Query: 181 XXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER 240 +RAA +RK+IAAAM+RSKREIPHYY+A+ I + L WL N +R ITER Sbjct: 151 --------GDRAADIRKTIAAAMTRSKREIPHYYVAETIPLAAMLAWLAQENTRRPITER 202 Query: 241 XXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK 300 ++F E NGF+RD F+AA VH+GV ISLR GGL+APA+ D K Sbjct: 203 LLPAAVLIKAVALSLRQFPELNGFYRDGAFEAAEAVHIGVAISLRQGGLMAPALLDAHAK 262 Query: 301 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK 360 L +LM +LTDLV R RAG+L+SSEMS PT+TVTNLGDQGV VFG+IYPPQVA+VGFG+ Sbjct: 263 PLTQLMQELTDLVRRCRAGTLKSSEMSAPTVTVTNLGDQGVAQVFGIIYPPQVALVGFGR 322 Query: 361 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 A++ GG++++ V +L+ADHR SDGHRGA FL+ +++ LQ P+ L++ Sbjct: 323 IAEQPWAEAGGLKIMPAVTASLSADHRVSDGHRGARFLSELSDRLQHPEALDR 375 >tr|B2UJI1|B2UJI1_RALPJ Tax_Id=402626 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Ralstonia pickettii] Length = 375 Score = 355 bits (912), Expect = 4e-96 Identities = 193/413 (46%), Positives = 255/413 (61%), Gaps = 38/413 (9%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 MI F++PALG+DMDEGTL EW VKPGD V +GQI+A+V+T+KAA+++E W EGTV EL+V Sbjct: 1 MIAFRLPALGADMDEGTLLEWQVKPGDTVKKGQIIAVVDTSKAAIDVESWHEGTVAELLV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRW 120 G + VGT +A LEPG KR + RR Sbjct: 61 TPGTKIPVGTPMAMFLEPGEAPGAV------KRQPDMPGAARPLPPP--------QTRRM 106 Query: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXX 180 SPAAR+ A+ +D+D ++GTG G +T++DVEH Sbjct: 107 ASPAARQAARERGIDIDTITGTGHGGVITLADVEHATPVGSAVT---------------- 150 Query: 181 XXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER 240 +RAA +RK+IAAAM+RSKREIPHYY+A+ I + L WL N +R ITER Sbjct: 151 --------GDRAADIRKTIAAAMTRSKREIPHYYVAETIPLAAMLAWLAQENTRRPITER 202 Query: 241 XXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK 300 ++F E NGF+RD F+AA VH+GV ISLR GGL+APA+ D K Sbjct: 203 LLPAAVLIKAVALSLRQFPELNGFYRDGAFEAAEAVHIGVAISLRQGGLMAPALLDAHAK 262 Query: 301 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK 360 L +LM +LTDLV R RAG+L+SSEMS PT+TVTNLGDQGV VFG+IYPPQVA+VGFG+ Sbjct: 263 PLTQLMQELTDLVRRCRAGTLKSSEMSAPTVTVTNLGDQGVAQVFGIIYPPQVALVGFGR 322 Query: 361 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 A++ GG++++ V +L+ADHR SDGHRGA FL+ +++ LQ P+ L++ Sbjct: 323 IAEQPWAEAGGLKIMPAVTASLSADHRVSDGHRGARFLSELSDRLQHPEALDR 375 >tr|B2JTY4|B2JTY4_BURP8 Tax_Id=391038 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Burkholderia phymatum] Length = 382 Score = 345 bits (885), Expect = 6e-93 Identities = 197/413 (47%), Positives = 247/413 (59%), Gaps = 31/413 (7%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 MIEF +P++G+DMDEGTL EW +KPGD V++GQIVAIV+T+KAAV+IE W EGTV EL+ Sbjct: 1 MIEFTLPSMGADMDEGTLLEWKIKPGDAVTKGQIVAIVDTSKAAVDIESWYEGTVYELIT 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRW 120 G+ + VGT +A LE G KR RR Sbjct: 61 EPGEKIPVGTPMAIFLERGESASELK-----KRTGAISAAGSPLSVDAVA------QRRK 109 Query: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXX 180 VSPAAR+ A HVDLD+V G+GP G+VT DVEH Sbjct: 110 VSPAARKHAHECHVDLDSVVGSGPGGSVTYDDVEHARRGAADIRAAPA------------ 157 Query: 181 XXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER 240 +R A MR IA+AM RSKREIPHYY+++ I + +L WL NA+RSI +R Sbjct: 158 --------GDRLAAMRTVIASAMERSKREIPHYYVSETIPLGTALKWLQAENARRSIDDR 209 Query: 241 XXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK 300 +RF E NGF+R F +A+ HVGV ISLR GGLVAPA+ D K Sbjct: 210 VLLAVLLLKAVAVTLKRFPELNGFYRAGSFLSASKTHVGVAISLRHGGLVAPALLDTETK 269 Query: 301 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK 360 L +LM +L DL R RAGSLRSSE+S+ TITVTNLGDQG VFGVIYPPQVA+VGFG+ Sbjct: 270 TLLQLMRELADLTKRCRAGSLRSSELSEATITVTNLGDQGTCEVFGVIYPPQVALVGFGR 329 Query: 361 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLLEK 413 +R +G + ++ TV TL+ADHR SDGHRGALFL +++ LQ P+ L++ Sbjct: 330 VIERPWAHNGEVTILPTVTATLSADHRVSDGHRGALFLLELSDALQHPEELDR 382 >tr|A5GEF2|A5GEF2_GEOUR Tax_Id=351605 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Geobacter uraniireducens] Length = 403 Score = 308 bits (790), Expect = 6e-82 Identities = 178/411 (43%), Positives = 231/411 (56%), Gaps = 8/411 (1%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EF+MP+LG+DM+ GTL EW V+ GD+V RG I+A+VET K +E+E +++G VD++ V Sbjct: 1 MAEFRMPSLGADMEAGTLVEWNVQSGDRVKRGDIIALVETDKGLIEVEVFEDGVVDKIHV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRW 120 G V VGT LA + GA R Sbjct: 61 QPGAKVPVGTALAFIRAEGAAPLPAAAVTEPTPAVVEPKRAPAAVPSPPLPVTPPGERVI 120 Query: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXX 180 SP+AR+LA L VDL A+ G+GP+GA+ +D+E Sbjct: 121 ASPSARKLAAELGVDLTAIHGSGPRGAIQRADIE--------LASRAAKPAPPAEKPAPP 172 Query: 181 XXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER 240 + + A MR++IAAAMSRS REIPHYYL EI ME +L WL N +RSI +R Sbjct: 173 PLPERPAPPDYQAGMRRAIAAAMSRSNREIPHYYLEMEIDMECALAWLEGENLKRSIKDR 232 Query: 241 XXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK 300 E NG+W DD Q + +H+G IS+R GGL+ PAIH+V Sbjct: 233 LLPAVLLLKAVARALADVPELNGYWLDDRHQVSEAIHIGFAISMRQGGLITPAIHNVDML 292 Query: 301 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK 360 DELMG + DL+ R RAG LRSSEM+D TITVTNLGD GV TVFGVIYPPQVA+VGFG+ Sbjct: 293 SHDELMGAMRDLITRTRAGRLRSSEMTDATITVTNLGDLGVKTVFGVIYPPQVALVGFGR 352 Query: 361 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 +R +G + V + +LA DHRA+DGHRG+ FL A+N+ LQ P+ L Sbjct: 353 IMERPWAENGMLGVRRVMSASLAGDHRATDGHRGSQFLEALNKHLQGPETL 403 >tr|Q6ALF2|Q6ALF2_DESPS Tax_Id=84980 (phdC)SubName: Full=Probable dihydrolipoamide acetyltransferase, component E2 of pyruvate dehydrogenase;[Desulfotalea psychrophila] Length = 397 Score = 300 bits (768), Expect = 2e-79 Identities = 178/417 (42%), Positives = 227/417 (54%), Gaps = 26/417 (6%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EF+MP+LG+DM EG L EW VK GD+V RG I+A VET K +EIE + +G +++++V Sbjct: 1 MTEFRMPSLGADMKEGRLVEWKVKLGDQVKRGDIIAEVETAKGVIEIEVFTDGVIEQILV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXX------KRXXXXXXXXXXXXXXXXXXXXX 114 G+ V VGTVLAT+ G K Sbjct: 61 QRGENVPVGTVLATIQGNGEQGRELREEALPEPVFKYKACLIAAHREEPAAEPPPAVVTA 120 Query: 115 XRHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXX 174 R +SP AR+L L V+L V GTG GA+T D+E Sbjct: 121 AGKRLRISPRARKLLAELDVELSTVQGTGQGGAITGIDIERAAAAEKAAA---------- 170 Query: 175 XXXXXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQ 234 Q+ + A MR++IA AM+RS REIPHYYLA I M +L WL N + Sbjct: 171 ----------QSVPSTPGAAMRQAIATAMARSNREIPHYYLASRIDMSNTLRWLEAENKK 220 Query: 235 RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAI 294 RSI ER + E NG+W D+ Q VH+G ISLR GGLVAPAI Sbjct: 221 RSIKERVLPVVPLIKATALALAKVPELNGYWLDNRQQPEEAVHIGFVISLRQGGLVAPAI 280 Query: 295 HDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVA 354 H K L ELM L+DL+ R R+G LRSSE++D T+T+TNLGD GV+ V GVIYPPQVA Sbjct: 281 HHANLKSLPELMETLSDLITRTRSGHLRSSELTDATVTITNLGDLGVEVVHGVIYPPQVA 340 Query: 355 IVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 +VGFGK ++ DG + + + TLAADHRA+DGHRGA FL A+N LQ+P+ L Sbjct: 341 LVGFGKILEQPWAKDGMLGIRPILTATLAADHRATDGHRGAQFLEALNHHLQKPEEL 397 >tr|Q6AIE3|Q6AIE3_DESPS Tax_Id=84980 SubName: Full=Probable pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase;[Desulfotalea psychrophila] Length = 397 Score = 295 bits (755), Expect = 7e-78 Identities = 175/417 (41%), Positives = 226/417 (54%), Gaps = 26/417 (6%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EF+MP+LG+DM EG L EW VK GD+V RG I+A VET K +EIE + +G +++++V Sbjct: 1 MTEFRMPSLGADMKEGRLVEWKVKLGDQVKRGDIIAEVETAKGVIEIEVFTDGVIEQILV 60 Query: 61 PVGDTVEVGTVLATLLEPG------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXX 114 G+ V VGTVLAT+ G K Sbjct: 61 QRGEKVPVGTVLATIRTAGEQGKVPGEAAPPEPVFKYKACLIAAHREEPAAEPPPAVATA 120 Query: 115 XRHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXX 174 R +SP AR+LA L V+L V GTG GA+T +D++ Sbjct: 121 AGKRLRISPLARKLAAELAVELSTVQGTGQGGAITHADIKRAAATKKASAPQVP------ 174 Query: 175 XXXXXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQ 234 + A MR++IA AM+RS REIPHYYLA I M +L WL N + Sbjct: 175 --------------SAPGAAMRQAIATAMARSNREIPHYYLATRIDMSNTLRWLEAENKK 220 Query: 235 RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAI 294 RSI ER + E NG+W D+ Q VH+G ISLR GGLVAPAI Sbjct: 221 RSIKERILPVVPLIKATALALAKVPELNGYWVDNRQQPEEAVHIGFVISLRQGGLVAPAI 280 Query: 295 HDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVA 354 H K L ELM L DL+ RAR+G LRSSE++D T+T+T+LGD GV+ V GVIYPPQ+A Sbjct: 281 HHADLKSLPELMEALYDLITRARSGHLRSSELTDATVTITSLGDLGVEVVHGVIYPPQIA 340 Query: 355 IVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 +VGFGK ++ DG + + + TLAADHRA+D HRGA FL A+N LQ+P+ L Sbjct: 341 LVGFGKILEQPWAKDGMLGIRPILTATLAADHRATDAHRGAQFLEALNHHLQKPEEL 397 >tr|C4DDQ6|C4DDQ6_9ACTO Tax_Id=446470 SubName: Full=Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component;[Stackebrandtia nassauensis DSM 44728] Length = 411 Score = 282 bits (722), Expect = 5e-74 Identities = 170/429 (39%), Positives = 225/429 (52%), Gaps = 36/429 (8%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EF+MP+LG+DMD GTL EWLV PGD VS+G IVA+VET KA +E+EC+ G + EL+V Sbjct: 1 MAEFRMPSLGADMDAGTLTEWLVAPGDHVSKGDIVAVVETAKADMEVECFDAGVIGELLV 60 Query: 61 PVGDTVEVGTVLATLL-----EPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXX 115 G V VGTVLAT++ PG R Sbjct: 61 HPGARVPVGTVLATIVTDDGGSPGEPAAAPAIEPAPPRADAPPEPPR------------- 107 Query: 116 RHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVE---HXXXXXXXXXXXXXXXXX 172 VSP R LA+ HVDL V TGP G VT +D++ H Sbjct: 108 -----VSPLVRHLARENHVDLAKVPATGPDGTVTRADLDRVLHRRRISPLARRLATELKV 162 Query: 173 XXXXXXXXXXXXQNKIAERAAQM----------RKSIAAAMSRSKREIPHYYLADEILME 222 + E A R++ A M+RSKREIPHYYLA I + Sbjct: 163 DLARIDADGPIHARHVREAATHRHPAERSTSAAREATARLMARSKREIPHYYLAATIDLG 222 Query: 223 KSLNWLTTRNAQRSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGI 282 +++WLT N + +++R + NG W DD FQAA + +G+ + Sbjct: 223 PAVDWLTDLNRRLPVSQRVLPAALLLVATARAAATVKDLNGHWIDDRFQAADRIRLGLAV 282 Query: 283 SLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVD 342 S+RGGGLV P I D A + E+M + DL RAR G LR+ E++DP+ITV+NLGD GVD Sbjct: 283 SVRGGGLVVPGIDDAAALSVPEMMDRVRDLATRARTGQLRAGELADPSITVSNLGDTGVD 342 Query: 343 TVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAIN 402 +V GVIYPPQVA+VGFG +R ++G + V V +L+ADHR +DG GA FL I+ Sbjct: 343 SVLGVIYPPQVALVGFGAITERPWAVNGLLGVRPVVTASLSADHRVTDGAVGARFLNHID 402 Query: 403 ELLQQPDLL 411 LL++P+ L Sbjct: 403 RLLREPEEL 411 >tr|A8FVB3|A8FVB3_SHESH Tax_Id=425104 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Shewanella sediminis] Length = 377 Score = 244 bits (622), Expect = 2e-62 Identities = 144/406 (35%), Positives = 213/406 (52%), Gaps = 29/406 (7%) Query: 6 MPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPVGDT 65 MP+LG+DM EG L EWLVK GD V RG I+A++ET K A+++E + G + E++ T Sbjct: 1 MPSLGADMTEGMLVEWLVKRGDPVKRGDIIAVIETQKGAIDMEVYHTGVISEILHQPVVT 60 Query: 66 VEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRWVSPAA 125 + VGTV+A + + R R SP Sbjct: 61 LPVGTVMARVETQASD-----------REVAATIAPQIDTVAPQIDTAADRVAAIASPIV 109 Query: 126 RRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQ 185 R++A +DL A+ G+GP+GA+ + D+ + Sbjct: 110 RKIAMGKSLDLTAIKGSGPKGAILLRDLPENTEEIRASTSD------------------R 151 Query: 186 NKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITERXXXXX 245 + + MR +IAAAMS+SK EIPH+Y + +I + + WL N R+ + Sbjct: 152 KQSSGITKSMRAAIAAAMSKSKNEIPHFYQSLDIELGNAQEWLKKTNEDRAPEQHILLLA 211 Query: 246 XXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADKKLDEL 305 ++ + NGF++++ F A +H+G IS+R GGLV PAIH V +DE Sbjct: 212 LLLKAVAKTLTKYPDLNGFYQENQFVHAKEIHIGNVISIRQGGLVVPAIHHVDKLSVDET 271 Query: 306 MGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGKPAQRV 365 M + D+ AR R G LRSSE++D TIT+TN+G++G DTVF VIYPPQVAI+GFGK + + Sbjct: 272 MQAIRDISARGRNGHLRSSELTDATITITNMGERGTDTVFAVIYPPQVAIIGFGKIRETL 331 Query: 366 CVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 ++D + + L+ADHR DG GA FL A+++ LQ+P+LL Sbjct: 332 QLVDAILVSRDVMSVCLSADHRVIDGMLGAKFLNALSKQLQKPELL 377 >tr|A6Q8W6|A6Q8W6_SULNB Tax_Id=387093 SubName: Full=Pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase;[Sulfurovum sp.] Length = 410 Score = 240 bits (612), Expect = 3e-61 Identities = 154/432 (35%), Positives = 214/432 (49%), Gaps = 50/432 (11%) Query: 4 FKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDE------ 57 FKMP+LG+DM+ GTL EW VK G+KV +GQ++A VE+ K +E+E +++G VD Sbjct: 4 FKMPSLGADMESGTLMEWKVKEGEKVKKGQVIAEVESNKGVIEVEVFEDGVVDRLLVEPG 63 Query: 58 --------LVVPVGDTV-------EVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXX 102 + V VG+ E+GT P + Sbjct: 64 TTCDVGTPIAVIVGENETAEALEKELGTQSGKEAAPKVSTETETTEKASEAKKPSKKESV 123 Query: 103 XXXXXXXXXXXXXR---HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXX 159 + H +SPAAR+ A+ L VDL+A++ +G + +VE Sbjct: 124 KEAKTTVTKEKPKKSTDHEIKISPAARKKAEELGVDLEALAAK-TEGKIGTDEVEAAAKT 182 Query: 160 XXXXXXXXXXXXXXXXXXXXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEI 219 + MRK+IAAAMSRS EIPHYYL+ I Sbjct: 183 AKQKRGG-------------------------SDSMRKAIAAAMSRSNAEIPHYYLSTSI 217 Query: 220 LMEKSLNWLTTRNAQRSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVG 279 M +L+WL +N +RSI ER Q E NGFW++D Q + ++ G Sbjct: 218 NMTPALDWLAEQNEKRSIKERILPAALTIRAVVKALQAVPELNGFWQNDTLQMSEVINPG 277 Query: 280 VGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQ 339 V I+ R GGLV PA+ + + LD M DL+ R R+G LRSSE++ TI +TNLGD Sbjct: 278 VAIAKRKGGLVTPALLNAQEMDLDGTMKAFHDLITRTRSGKLRSSEITQQTIVITNLGDI 337 Query: 340 GVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLA 399 GV+ V GVIYPPQVA+VG G+ A + + V ++ TLA DHRA+DG GALFL Sbjct: 338 GVEEVLGVIYPPQVALVGLGRIADAPWIEGDALAVRKVMRATLAGDHRATDGRTGALFLN 397 Query: 400 AINELLQQPDLL 411 ++E LQ+P+ L Sbjct: 398 KLDEFLQKPEEL 409 >tr|B4UXF3|B4UXF3_9ACTO Tax_Id=465541 SubName: Full=Putative uncharacterized protein;[Streptomyces sp. Mg1] Length = 443 Score = 231 bits (590), Expect = 1e-58 Identities = 127/288 (44%), Positives = 168/288 (58%), Gaps = 9/288 (3%) Query: 122 SPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXXX 181 SP ARRLAQS+ VDL + GTG G + DV Sbjct: 163 SPLARRLAQSMGVDLGGLWGTGRNGTIRADDVRAAAVDSLPREAEPQEPVEKRVLASP-- 220 Query: 182 XXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITERX 241 AE A R +IAA M+R+KREIPHYYL+ ++ + ++ W+ +NA + + +R Sbjct: 221 -------AESAPGARAAIAALMTRAKREIPHYYLSTKVDLAAAMTWMRDQNAGKPVAQRL 273 Query: 242 XXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADKK 301 + E NG W++D F A+GV +G+ +SLRGGGL APA+ D Sbjct: 274 VPVALLLKAVALAAHQVPELNGHWKNDAFVPASGVRLGIAVSLRGGGLTAPALADADTMP 333 Query: 302 LDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGKP 361 L ELM L DLV+RAR G LR+SE +DPT+TVTNLGDQGV+ VFGVIYPPQVA+VG G+ Sbjct: 334 LPELMEALRDLVSRARGGRLRTSETTDPTLTVTNLGDQGVEAVFGVIYPPQVALVGLGRV 393 Query: 362 AQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPD 409 ++ ++G + V TV TL+ADHRASDG GA FL I+ LLQ+P+ Sbjct: 394 IEQPVAVNGMLTVHPTVTATLSADHRASDGATGARFLTVIDRLLQRPE 441 Score = 107 bits (266), Expect = 4e-21 Identities = 61/158 (38%), Positives = 84/158 (53%), Gaps = 10/158 (6%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EF MP+LG+DM+EGTL EWLV PGD V++G +VA+VET K+ +E+EC+ GT+ L+V Sbjct: 1 MAEFTMPSLGADMEEGTLVEWLVGPGDTVTKGDVVAVVETAKSTIEVECFDSGTISALLV 60 Query: 61 PVGDTVEVGTVLATL---LEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRH 117 G TV VGT +A++ + P A K+ Sbjct: 61 EPGTTVPVGTPMASIDSAIAPPA-------RPAAKQPITPTPAPSPDLQPAPSRPVTRTE 113 Query: 118 RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEH 155 R +P R LA+ +DL V G+G G +T DVEH Sbjct: 114 RAVSTPLVRHLAEEKGIDLSTVHGSGKGGRITRYDVEH 151 >tr|A0JS87|A0JS87_ARTS2 Tax_Id=290399 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Arthrobacter sp.] Length = 477 Score = 227 bits (579), Expect = 2e-57 Identities = 126/294 (42%), Positives = 172/294 (58%), Gaps = 4/294 (1%) Query: 122 SPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXXX 181 SP ARRLA L VD+ V GTGP GAVT +DV+ Sbjct: 184 SPRARRLADQLGVDIGGVPGTGPDGAVTEADVQRAVSGHTAAAPAEEALPEEATVPGAEA 243 Query: 182 XXXQ----NKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSI 237 + ++ +R + +R++I + M+RSK+ IPHYY++ + + ++ W+ N QR + Sbjct: 244 LPPKEAPPSEAQDRLSSLRRAIGSLMTRSKKSIPHYYVSTTLDLRAAIAWMQQVNEQRPV 303 Query: 238 TERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDV 297 R + E NGF+ D F+ ++ VH+GV ++LR GGLVAPAIHD Sbjct: 304 ASRLVPSALLLKATALAAKEVPEVNGFFTDGVFRPSSSVHLGVAVALRHGGLVAPAIHDA 363 Query: 298 ADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVG 357 +D LM L DLV+RARAG L+ +EM+DPT+TVTNLGD GV+ V+GVIYPPQVA+VG Sbjct: 364 DTLAVDVLMQQLRDLVSRARAGRLQRAEMADPTLTVTNLGDLGVEAVYGVIYPPQVAMVG 423 Query: 358 FGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 GK ++ DG + V V TL+ADHR SDG RG FLA I+ELLQ+P+ L Sbjct: 424 LGKLVEQPWAHDGMLGVRPAVTATLSADHRVSDGLRGGRFLARIDELLQKPEEL 477 Score = 96.7 bits (239), Expect = 5e-18 Identities = 57/154 (37%), Positives = 76/154 (49%), Gaps = 4/154 (2%) Query: 6 MPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPVGDT 65 MP+LG+DM+ G + EWL+KPGD V RG +VA+V+T K +++E ++EG V EL+V VG T Sbjct: 1 MPSLGADMEHGKMVEWLIKPGDYVHRGDVVAVVDTDKTVMDVESFEEGVVAELLVDVGTT 60 Query: 66 VEVGTVLATLL----EPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRWV 121 V +GT LA + + K V Sbjct: 61 VPIGTPLARITRTPDDGAGQAGGRPAGPHAKPASGAAETAVAAAAAEPAGAAAAAAAVQV 120 Query: 122 SPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEH 155 P R LA L VD + GTG GAVT +DVEH Sbjct: 121 PPPVRHLAHQLGVDTAGIRGTGRHGAVTRADVEH 154 >tr|Q0A5F2|Q0A5F2_ALHEH Tax_Id=187272 SubName: Full=Catalytic domain of components of various dehydrogenase complexes;[Alkalilimnicola ehrlichei] Length = 441 Score = 220 bits (560), Expect = 3e-55 Identities = 124/291 (42%), Positives = 166/291 (57%), Gaps = 14/291 (4%) Query: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXX 180 +SPAARR A+ L VD + G+GP GAV DVEH Sbjct: 165 LSPAARRRARELGVDPAGLRGSGPGGAVLAGDVEHAAGARPAAAPAEPPPTRPAGFDRD- 223 Query: 181 XXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITER 240 +MR++IAAAM+RSKREIPHYYL + ++ + +WLT N +R R Sbjct: 224 -------------EMRRAIAAAMTRSKREIPHYYLNTTVDLKAAHDWLTAYNRERPPESR 270 Query: 241 XXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADK 300 +++ + NG + + GFQ A VH+GV I LRGGGL+APA+ D Sbjct: 271 LVMAALFAKAAARALRKYPDLNGHYHEQGFQPADSVHLGVAIHLRGGGLIAPALLDADRL 330 Query: 301 KLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGK 360 + +LM L DL+ RAR G LRSSE++ PT T+T LG++GVDTV+GVI+PPQVA++GFG+ Sbjct: 331 NVPDLMVRLRDLIDRARGGGLRSSEVTAPTATITALGERGVDTVYGVIHPPQVAMIGFGR 390 Query: 361 PAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 +R V+ G+ V +LAADHR DGH GA FL I + LQQP+ L Sbjct: 391 VRRRPVVVGDGLAARPAVDVSLAADHRVCDGHLGARFLNRIEQDLQQPEAL 441 Score = 77.0 bits (188), Expect = 4e-12 Identities = 34/75 (45%), Positives = 51/75 (68%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M +F MP+LG+DM G L EW V+PGD+V +GQ++A+VET K A+E+E ++ G V+ L Sbjct: 1 MSDFLMPSLGADMASGELVEWRVRPGDRVEKGQVIAVVETNKGAIEVEVFESGVVEALYE 60 Query: 61 PVGDTVEVGTVLATL 75 G + VG +A + Sbjct: 61 EPGTRLPVGAPMARI 75 >tr|A4FCC8|A4FCC8_SACEN Tax_Id=405948 SubName: Full=Probable pyruvate dehydrogenase, E2 component,dihydrolipoamide acetyltransferase; EC=2.3.1.12;[Saccharopolyspora erythraea] Length = 434 Score = 202 bits (514), Expect = 6e-50 Identities = 121/294 (41%), Positives = 157/294 (53%), Gaps = 18/294 (6%) Query: 118 RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXX 177 RR VSP ARRLA L V+ + ++G+GP GAV DV Sbjct: 159 RRPVSPYARRLATELGVEPERLTGSGPDGAVHARDVHRATQRPAEATPAPATAEG----- 213 Query: 178 XXXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSI 237 R MR++IAA M++SKREIPHYYL I + +++ WL N + Sbjct: 214 -------------RPESMRRAIAALMAKSKREIPHYYLTSTIDVGRAVEWLHEHNRHVPV 260 Query: 238 TERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDV 297 TER + E NG W DD + VH+GV +SL GGGL+ P + D Sbjct: 261 TERLVPAALLLKAAALAARGVPELNGHWVDDRLVPSDSVHLGVAVSLHGGGLLTPTLADA 320 Query: 298 ADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVG 357 L ELM L D+VARARA LRSS+ + TITVTNLG+ GV++V GVIYPPQV +VG Sbjct: 321 DQLPLSELMHRLRDVVARARAARLRSSDTTTATITVTNLGELGVESVQGVIYPPQVGLVG 380 Query: 358 FGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 FG +R + I + V TL+ DHRASDG GA FL ++ +LQ+P+ L Sbjct: 381 FGAVMRRPWAVGELIGIRPVVTATLSGDHRASDGATGARFLNTVDAVLQRPEEL 434 Score = 105 bits (261), Expect = 1e-20 Identities = 61/154 (39%), Positives = 84/154 (54%), Gaps = 17/154 (11%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M EF+MP+LG+DMD+GTL EWLV+PGD +++G I+A V+T K+ +++EC++ G VD L+V Sbjct: 1 MAEFRMPSLGADMDQGTLVEWLVRPGDTINKGDIIAAVDTNKSTIDVECFETGVVDRLLV 60 Query: 61 PVGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRW 120 G V VGT LA ++ P A R Sbjct: 61 DPGSIVPVGTPLA-VITPRA----------------RGAPAAPPPPQPAPVAKAHRAVPT 103 Query: 121 VSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVE 154 VSP R+LA VDL + GTG GA+T +DVE Sbjct: 104 VSPPVRKLAARTGVDLTTLHGTGRAGAITRADVE 137 >tr|A3JZ33|A3JZ33_9RHOB Tax_Id=388399 SubName: Full=Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex;[Sagittula stellata E-37] Length = 433 Score = 170 bits (430), Expect = 3e-40 Identities = 128/427 (29%), Positives = 184/427 (43%), Gaps = 21/427 (4%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 +E +MPAL M+EGTL +WLVK GD VS G ++A +ET KA +E E EG + +VV Sbjct: 3 VEIQMPALSPTMEEGTLAKWLVKEGDTVSSGDVLAEIETDKATMEFEAVDEGVIGRIVVA 62 Query: 62 VGDT-VEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRR- 119 G V+VGTV+A LLE G R Sbjct: 63 EGTAEVKVGTVIAVLLEEGETAEDIGTSAESTAETPATPEEEPAAPKTDSHAAPPAPERA 122 Query: 120 -----WVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXX 174 + SP ARR+A +DL ++G+GP+G + +DVE Sbjct: 123 DGERIFASPLARRIAAQKGLDLSRITGSGPRGRIVKADVESATAEPAAAKPAAAAATPAV 182 Query: 175 XXXXXXXXXXQ-NKIAERAAQ----------MRKSIAAAMSRSKREIPHYYLADEILMEK 223 + +A A MR++IAA ++ +K+ IPH+YL +I ++ Sbjct: 183 APAKAAPTPVDPSSVAALYADRDYTEVPLDGMRRTIAARLTEAKQTIPHFYLRRDITLDA 242 Query: 224 SLNWLTTRNAQRSITE-RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGI 282 + + N Q + + Q+ + N W D T V V + Sbjct: 243 LMAFRAQLNEQLAPRGVKLSVNDFIIKACAMALQQVPKANAVWAGDRILQLTPSDVAVAV 302 Query: 283 SLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVD 342 ++ GG L P + D K L L D+ DL ARAR L SE + ++NLG G++ Sbjct: 303 AIEGG-LFTPVLRDAHQKTLSALSADMKDLAARARDRKLAPSEYQGGSFAISNLGMFGIE 361 Query: 343 TVFGVIYPPQVAIVGFGKPAQRVCV-IDGGIRVVTTVQGTLAADHRASDGHRGALFLAAI 401 VI PP AI+ G ++ V DG + V T + TL+ DHR DG GA L AI Sbjct: 362 NFDAVINPPHGAILAVGAGVKKPVVNADGALAVATVMSVTLSVDHRVIDGALGAELLTAI 421 Query: 402 NELLQQP 408 L+ P Sbjct: 422 KGNLENP 428 >tr|Q1D8Y6|Q1D8Y6_MYXXD Tax_Id=246197 (pdhC)SubName: Full=Pyruvate dehydrogenase complex , E2 component, dihydrolipoamide acetyltransferase; EC=2.3.1.12;[Myxococcus xanthus] Length = 527 Score = 168 bits (425), Expect = 1e-39 Identities = 123/410 (30%), Positives = 179/410 (43%), Gaps = 9/410 (2%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I +MP+L M EG + +WL K GDKVS G VA VET K+ +EIE + GT+ E+VV Sbjct: 125 IAIQMPSLSPTMTEGKIVKWLKKQGDKVSSGDAVAEVETDKSNLEIEAYDNGTLAEIVVG 184 Query: 62 VGDTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRWV 121 +VG +A L GA K R R Sbjct: 185 ENQMAKVGAPIAYLTAKGAKAAPAAPAAQPKPPAPAPEKPAAAKPAAAPAQAGGRRLR-A 243 Query: 122 SPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXXX 181 SP A+R+A+ +DL VSG+GP G V D+E Sbjct: 244 SPVAKRIAREKGLDLTQVSGSGPSGRVVKRDIEEALARGPAAVPAAKKAPAAQPAPGVRP 303 Query: 182 XXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSITERX 241 ++ MRK IA M+ K +PH+YL E+ ME + R +++ + Sbjct: 304 EPTVLPLSS----MRKVIAQRMTEVKPGVPHFYLTIEVDMEAASK---VREEAKAMDLKV 356 Query: 242 XXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADKK 301 +R+ + N + D V VG+ ++L G L+ P + D K Sbjct: 357 SVNDLIVKAVAMAVRRYPKINVSLQGDKVVQFHSVDVGIAVALEEG-LITPILRDADQKG 415 Query: 302 LDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGKP 361 L + + +L RAR +L+ E + +ITV+NLG G+D VI PPQ +I+ G Sbjct: 416 LQAIASGVRELAERARKRALKPEEYTGGSITVSNLGMYGIDQFVAVINPPQASILAVGAV 475 Query: 362 AQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 +++ V DG + V + TL+ DHR DG GA FL + LL+ P L Sbjct: 476 SEKAVVRDGQLAVRKMMTATLSCDHRVIDGAIGAEFLRELRGLLEHPTRL 525 Score = 61.2 bits (147), Expect = 2e-07 Identities = 31/72 (43%), Positives = 46/72 (63%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I +MP+L M EG + +WL K GDKVS G VA VET K+ +EIE + +G + +++V Sbjct: 3 IPIQMPSLSPTMTEGKIVKWLKKQGDKVSSGDAVAEVETDKSNLEIEAYDDGYLLQVLVG 62 Query: 62 VGDTVEVGTVLA 73 G+ +VG +A Sbjct: 63 EGEMAKVGAPIA 74 >tr|A8LQM9|A8LQM9_DINSH Tax_Id=398580 (pdhC1)SubName: Full=Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; EC=2.3.1.12;[Dinoroseobacter shibae] Length = 420 Score = 168 bits (425), Expect = 1e-39 Identities = 128/418 (30%), Positives = 184/418 (44%), Gaps = 12/418 (2%) Query: 3 EFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPV 62 E MPAL M+EGTL +W+VK GD VS G ++A +ET KA +E E +G + +++V Sbjct: 4 EILMPALSPTMEEGTLAKWMVKEGDSVSSGDLLAEIETDKATMEFEAVDDGIIGKILVAA 63 Query: 63 G-DTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRRWV 121 G D V+V T++A LLE G R + Sbjct: 64 GTDDVKVNTLIAILLEEGEELGAEKPAEQPPEPASVQQEAAPQETAKAPPPKTG-DRVFA 122 Query: 122 SPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXXXX 181 SP ARRLA+ +DL + G+GP G + +DV+ Sbjct: 123 SPLARRLAKQKGLDLSEIRGSGPHGRIVKADVD-AAEQPAAVPEQAAAPQTRQPEGPKSA 181 Query: 182 XXXQNKIAERAAQ------MRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQR 235 + A+R MRK+IAA ++ +K+ IPH+YL ++ L + T NAQ Sbjct: 182 SSVASIFADRPFTEVSLDGMRKTIAARLTEAKQTIPHFYLRRAANLDALLTFRTELNAQL 241 Query: 236 SIT-ERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPAI 294 + + ++ Q N W +D V V +++ GG L P I Sbjct: 242 APSGKKLSVNDFVIKACARALQSVPHANAVWAEDRILQMQRSDVAVAVAIEGG-LFTPVI 300 Query: 295 HDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVA 354 D K + L ++ DL ARAR L SE T ++NLG G++ VI PP A Sbjct: 301 KDADQKSISALSEEMKDLAARARERKLAPSEYVGGTFAISNLGMFGIENFDAVINPPHGA 360 Query: 355 IVGFGKPAQRVCV-IDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQPDLL 411 I+ G ++ V DG + V T + TL+ DHR DG GA LA I L+ P LL Sbjct: 361 ILAVGAGVKKPTVDADGAVTVATQMSMTLSVDHRVIDGSVGAALLAEIVSGLENPLLL 418 >tr|Q164R3|Q164R3_ROSDO Tax_Id=375451 (pdhC)SubName: Full=Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; EC=2.3.1.12;[Roseobacter denitrificans] Length = 431 Score = 167 bits (424), Expect = 2e-39 Identities = 132/424 (31%), Positives = 182/424 (42%), Gaps = 19/424 (4%) Query: 3 EFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPV 62 E MPAL M+EGTL +WLVK GD V+ G I+A +ET KA +E E EGT+ +++V Sbjct: 4 EILMPALSPTMEEGTLAKWLVKEGDTVASGDIMAEIETDKATMEFEAVDEGTIGKILVEE 63 Query: 63 G-DTVEVGTVLATLLEPGAXXXXXXXXXXX-----KRXXXXXXXXXXXXXXXXXXXXXXR 116 G + V+V T +A LLE G K Sbjct: 64 GTEGVKVNTPIAVLLEDGESADDISAEPEPAAAATKEDAPAPTPEPTATPAPAAPQSSDG 123 Query: 117 HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXX 176 R + SP ARR+A S VDL V G+GP G + +DVE Sbjct: 124 SRIFASPLARRIAASNGVDLATVKGSGPHGRIVKADVEGLSASAAAPAPAAPGPAAPAPS 183 Query: 177 XXXXXXXXQNKIAE----RAAQ------MRKSIAAAMSRSKREIPHYYLADEILMEKSLN 226 + RA MRK+IAA ++ +K+ IPH+YL +I ++ L Sbjct: 184 APVASGPAAEAVMAMYEGRAYDEISLNGMRKTIAARLTEAKQSIPHFYLRRDIELDALLA 243 Query: 227 WLTTRNAQ-RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLR 285 + N Q S + Q + N W D T V V +++ Sbjct: 244 FRGQLNKQLESRGVKLSVNDFIIKACALALQTVPDANAVWAGDRMLKLTPSDVAVAVAIE 303 Query: 286 GGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVF 345 GG L P + D K L L ++ DL ARAR L E + ++NLG G+D Sbjct: 304 GG-LFTPVLRDAEMKSLSALSAEMKDLAARARDRKLAPHEYQGGSFAISNLGMFGIDNFD 362 Query: 346 GVIYPPQVAIVGFGKPAQRVCV-IDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINEL 404 VI PP AI+ G ++ V DG + V T + TL+ DHR DG GA ++AI E Sbjct: 363 AVINPPHGAILAVGAGVKKPVVGKDGELAVATVMSVTLSVDHRVIDGALGAQLISAIKEN 422 Query: 405 LQQP 408 L+ P Sbjct: 423 LENP 426 >tr|B9QS00|B9QS00_9RHOB Tax_Id=244592 SubName: Full=Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; EC=2.3.1.12;[Labrenzia alexandrii DFL-11] Length = 441 Score = 164 bits (416), Expect = 1e-38 Identities = 124/437 (28%), Positives = 183/437 (41%), Gaps = 35/437 (8%) Query: 6 MPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPVG-D 64 MPAL M+EG L +WLVK GD VS G ++A +ET KA +E+E EGTV ++VV G + Sbjct: 1 MPALSPTMEEGNLAKWLVKEGDTVSAGDVIAEIETDKATMEVEAVDEGTVGKIVVEAGTE 60 Query: 65 TVEVGTVLATLLE---------------PGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXX 109 V+V ++A LLE P A Sbjct: 61 GVKVNDLIAVLLEDGEDASAIDTSGAAAPAAPAQSPAPAADAGAKEVIPVGAEAATDPIP 120 Query: 110 XXXXXXRHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXX 169 R + SP ARRLAQ +DL A+SG+GP G + D+E Sbjct: 121 APKAADGGRIFASPLARRLAQINGLDLKALSGSGPHGRIVKKDIEAAVAAGTSKAAAAPA 180 Query: 170 XXXXXXXXXXXXXXXQN-----KIAERAAQ-------MRKSIAAAMSRSKREIPHYYLAD 217 + K+ E + MRK+IA ++ SK+ IPH+Y++ Sbjct: 181 AAEAPKAAAATPAAGPSSDQVLKLFEEGSYELVPHDGMRKTIAKRLTESKQTIPHFYVSV 240 Query: 218 E------ILMEKSLNWLTTRNAQRSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQ 271 + + + LN + + + + + + N W DD Sbjct: 241 DCELDALLALRSQLNGAASTDKEGKPAYKLSVNDMTIKALALALRDVPDANVSWTDDNMV 300 Query: 272 AATGVHVGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTI 331 VGV +S+ GG L+ P I +K L + ++ D+ ARA++ L+ E T Sbjct: 301 KHKHADVGVAVSIPGG-LITPIIRRAEEKPLSVISNEMKDMGARAKSKKLQPQEYQGGTT 359 Query: 332 TVTNLGDQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDG 391 V+N+G GV V+ PP I+ G QR V DG + + T + TL+ DHR DG Sbjct: 360 AVSNMGMMGVKDFSAVVNPPHATILAVGAGEQRPVVKDGALAIATVMSVTLSTDHRCVDG 419 Query: 392 HRGALFLAAINELLQQP 408 GA LAA ++ P Sbjct: 420 ALGAELLAAFKGYIENP 436 >tr|Q0BSW9|Q0BSW9_GRABC Tax_Id=391165 SubName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; EC=2.3.1.12;[Granulibacter bethesdensis] Length = 416 Score = 163 bits (413), Expect = 3e-38 Identities = 117/416 (28%), Positives = 184/416 (44%), Gaps = 24/416 (5%) Query: 6 MPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPVG-D 64 MPAL M EGTL WL K GD ++ G ++A +ET KA +E+E EG + ++VP G + Sbjct: 7 MPALSPTMTEGTLARWLKKEGDTITAGDVIAEIETDKATMEVEAVDEGVLGRILVPDGTE 66 Query: 65 TVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXX------RHR 118 V V +A L+E G + +R Sbjct: 67 GVAVNAPIAILVEEGEAIPDQGDIPAPAKASAIPAAESSVPAKLEPKAIASSGPDRTENR 126 Query: 119 RWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXX 178 + SP ARR+A+ +DL +++G+GP G + +DVE Sbjct: 127 IFASPLARRIAKEAGIDLTSLTGSGPSGRILRADVEKAKGTGGKPASASTAAPAATGAT- 185 Query: 179 XXXXXXQNKIAERAAQMRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQRSIT 238 +K+ + MR++IA ++ +K+ IPH+Y+ ++ ++ L NA RS Sbjct: 186 -------HKLVPHSG-MRRTIARRLTEAKQTIPHFYVTMDVALDALLKLRADLNA-RSPA 236 Query: 239 E------RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAP 292 E + +R N W +DG V + V +S+ G L+ P Sbjct: 237 EGQEGAFKLSVNDLIIKAAGLALRRVPGVNAAWSEDGILLFEDVDISVAVSIPDG-LITP 295 Query: 293 AIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQ 352 I K + + ++ +L ARAR G L+ S+ +++NLG GV +I PPQ Sbjct: 296 IIRQADRKGVVSISTEMKELAARARKGGLQPSDYQGGGFSISNLGMYGVRDFAAIINPPQ 355 Query: 353 VAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQP 408 AI+ G QR V DG + V T + TL+ DHR DG GA +L A ++++ P Sbjct: 356 AAILAVGAGEQRPVVRDGALAVATVMSCTLSVDHRVVDGALGAQWLGAFRQIVEDP 411 >tr|D0CY56|D0CY56_9RHOB Tax_Id=644107 SubName: Full=Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; EC=2.3.1.12;[Silicibacter lacuscaerulensis ITI-1157] Length = 437 Score = 163 bits (412), Expect = 4e-38 Identities = 126/431 (29%), Positives = 183/431 (42%), Gaps = 27/431 (6%) Query: 3 EFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPV 62 E MPAL M+EGTL +WLVK GD VS G ++A +ET KA +E E EG V ++++P Sbjct: 4 EILMPALSPTMEEGTLAKWLVKEGDTVSSGDLLAEIETDKATMEFEAVDEGVVGKILIPE 63 Query: 63 G-DTVEVGTVLATLLEPG------------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXX 109 G + V+V T +A LLE G A + Sbjct: 64 GTEGVKVNTPIAVLLEEGESADDIAAVPAKAPEAAPAADAGNEAAAPAASEAPAPASATA 123 Query: 110 XXXXXXRHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXX 169 R + SP ARR+A +DL + G+GP G + +DVE Sbjct: 124 APVKADGGRIFASPLARRIAAQKGLDLAQIKGSGPHGRIVKADVE-GATAPAAAPAPAAA 182 Query: 170 XXXXXXXXXXXXXXXQNKIAE----------RAAQMRKSIAAAMSRSKREIPHYYLADEI 219 + +A + MRK+IAA ++ +K+ IPH+YL +I Sbjct: 183 ASAAPAPAAAPAGPSADMVARMYEGREYQEVKLDGMRKTIAARLAEAKQTIPHFYLRRDI 242 Query: 220 LMEKSLNWLTTRNAQ-RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHV 278 ++ L + + N Q S + Q+ E N W D V Sbjct: 243 KLDALLKFRSQLNKQLESRGVKLSVNDFIIKAVANALQQVPECNAVWAGDRVLQLKPSDV 302 Query: 279 GVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGD 338 V +++ GG L P + D K L L ++ DL ARAR L E T ++NLG Sbjct: 303 AVAVAIEGG-LFTPVLQDADTKSLSALSTEMKDLAARARERKLAPHEYQGGTFAISNLGM 361 Query: 339 QGVDTVFGVIYPPQVAIVGFGKPAQRVCV-IDGGIRVVTTVQGTLAADHRASDGHRGALF 397 G+D ++ PP I+ G A++ V DG + V T + T++ DHR DG GA Sbjct: 362 YGIDNFDAIVNPPHAGILAVGTGAKKPVVGEDGELTVATVMSVTMSVDHRVIDGALGAQL 421 Query: 398 LAAINELLQQP 408 L AI + L+ P Sbjct: 422 LQAIVDNLENP 432 >tr|A8GXH9|A8GXH9_RICB8 Tax_Id=391896 SubName: Full=Branched-chain alpha-keto acid dehydrogenase subunit E2;[Rickettsia bellii] Length = 418 Score = 162 bits (411), Expect = 6e-38 Identities = 117/433 (27%), Positives = 183/433 (42%), Gaps = 45/433 (10%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I+ MPAL M EG L WL K GDK++ G+++A +ET KA +E+E EGT+ ++++P Sbjct: 3 IKLLMPALSPTMTEGNLARWLKKEGDKINPGEVIAEIETDKATMEVEAVDEGTLAKIIIP 62 Query: 62 VGD-TVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRH--- 117 G V V +++A L+E G Sbjct: 63 QGSQNVPVNSLIAVLIEEGEELSGIEEFIAKNNSNSPKKEEISKPAETIAPQNVKEENIT 122 Query: 118 --------RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXX 169 + + SP A+RLA+ +V ++ + G+GP G + DV Sbjct: 123 TASDQNNIKVFASPLAKRLAKIQNVRIEEIKGSGPHGRIIKQDV---------------- 166 Query: 170 XXXXXXXXXXXXXXXQNKIAERAAQ---------MRKSIAAAMSRSKREIPHYYLADEIL 220 NKI R + +RK IA + SK+ +PH+YL+ E Sbjct: 167 -----LSHKGGSKALSNKIVSRNPEEYRLAPNNNIRKIIAKRLLESKQTVPHFYLSIECN 221 Query: 221 MEKSLNWLTTRNAQ--RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHV 278 ++K L+ N + + Q N W DD + V + Sbjct: 222 VDKLLDIREDINKSFGDDKSAKISVNDFIILAVAKALQEVPNANASWGDDAIRYYNNVDI 281 Query: 279 GVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGD 338 V +++ G LV P I + K + +L ++ L+ +AR L S E T++NLG Sbjct: 282 SVAVAIENG-LVTPIIRNADQKNIVDLSSEMKGLIKKARENKLTSEEFQGGGFTISNLGM 340 Query: 339 QGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFL 398 G+ +I PPQ I+G G ++R V + I + T + TL+ADHR DG GA FL Sbjct: 341 YGIKNFNAIINPPQSCIMGVGSSSKRAIVKNDQISIATIMDVTLSADHRVVDGAVGAEFL 400 Query: 399 AAINELLQQPDLL 411 AA ++ P L+ Sbjct: 401 AAFKRFIESPALM 413 >tr|A4TXZ0|A4TXZ0_9PROT Tax_Id=55518 (pdhC)SubName: Full=Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; EC=2.3.1.12;[Magnetospirillum gryphiswaldense] Length = 419 Score = 162 bits (409), Expect = 1e-37 Identities = 122/416 (29%), Positives = 176/416 (42%), Gaps = 13/416 (3%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 IE MPAL M EGTL WL K GD V G ++A +ET KA +E E EG + ++++ Sbjct: 3 IELLMPALSPTMTEGTLARWLKKEGDAVKSGDVLAEIETDKATMEFEAVDEGVLGKILIA 62 Query: 62 VGDT-VEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRH--- 117 G + V V T + LLE G K H Sbjct: 63 DGTSGVAVNTPIGVLLEEGEDASSIVAKP--KAAAPAAVAPAAAAAPAAAAAPAPSHGGE 120 Query: 118 RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXX 177 R + SP A+R+A +DL AV G+GP G V +DVE Sbjct: 121 RVFASPLAKRIAADAGLDLKAVKGSGPYGRVVKADVEQALKGGVAAAPVATAAAPVAAAK 180 Query: 178 XXXXXXXQNKIAERAAQ-----MRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRN 232 N + MRK IA ++ +K IPH+YL+ + ++ L + N Sbjct: 181 AAPAPAVANPFEPAFEEIPNSSMRKVIARRLTEAKSTIPHFYLSIDCELDALLKVRSDLN 240 Query: 233 AQRSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAP 292 RS + ++ N W ++ + T V V V ++ G L+ P Sbjct: 241 G-RSDAYKLSVNDFIIRAVALALKKVPAANASWGEEAIKRYTDVDVSVAVATPNG-LITP 298 Query: 293 AIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQ 352 +H K L + ++ +L A+AR G L+ E T++NLG GV +I PPQ Sbjct: 299 IVHHADHKGLAAISNEMKELAAKARDGKLKPEEFQGGGFTISNLGMFGVKDFAAIINPPQ 358 Query: 353 VAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQP 408 I+ G QR V G + + T + TL+ DHR DG GA FLAA +L++ P Sbjct: 359 GCILAVGAGEQRPVVKAGALAIATVMTCTLSVDHRVVDGAVGAEFLAAFKKLVEDP 414 >tr|B6AW84|B6AW84_9RHOB Tax_Id=314270 SubName: Full=Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; EC=2.3.1.12;[Rhodobacterales bacterium HTCC2083] Length = 422 Score = 161 bits (408), Expect = 1e-37 Identities = 121/416 (29%), Positives = 179/416 (43%), Gaps = 10/416 (2%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 IE MPAL M++GTL +WLVK GD VS G ++A +ET KA +E E EG + +++V Sbjct: 3 IEILMPALSPTMEDGTLAKWLVKEGDTVSSGDLLAEIETDKATMEFEAVDEGVIGKILVE 62 Query: 62 VGDT-VEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRHRR- 119 G V V + +A LLE G R Sbjct: 63 AGTAGVLVNSPIALLLEDGEDSAEVVASSQTAPAPIAPEVLSTPVATAPAPKLTQTGDRV 122 Query: 120 WVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXXXXXXXXXX 179 + SP ARR+A +DL ++G+GP+G + +DVE+ Sbjct: 123 FASPLARRIAADKGIDLATITGSGPRGRIVKADVENAQSAPAAQPAAIPTPQTAKAPDTN 182 Query: 180 XXXXXQNKIAERAAQ-----MRKSIAAAMSRSKREIPHYYLADEILMEKSLNWLTTRNAQ 234 + + MRK+IAA ++ +K+ IPH+YL +I ++ L + + N Q Sbjct: 183 PSQIAKMYEGREFTELPLDGMRKTIAARLTEAKQNIPHFYLRRDIHLDALLKFRSQLNKQ 242 Query: 235 RSITE-RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISLRGGGLVAPA 293 + + + Q+ N W D V V +++ GG L P Sbjct: 243 LAARDIKLSVNDFIIKACALALQQVPAANAVWAGDRVLQMKASDVAVAVAIEGG-LFTPV 301 Query: 294 IHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQV 353 + D K L L + DL RAR L E + ++NLG G++ VI PP Sbjct: 302 LQDADSKSLSALSAQMKDLANRARDRKLAPHEYMGGSFAISNLGMMGIENFDAVINPPHG 361 Query: 354 AIVGFGKPAQRVCV-IDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQP 408 AI+ G A++ V DG + + T + TL+ DHR DG GA LAAI L+ P Sbjct: 362 AILAVGAGAKKPIVNSDGDLDIATVMSVTLSVDHRVIDGALGADLLAAIKANLENP 417 >tr|Q28RQ7|Q28RQ7_JANSC Tax_Id=290400 SubName: Full=Dihydrolipoamide acetyltransferase long form;[Jannaschia sp.] Length = 441 Score = 161 bits (407), Expect = 2e-37 Identities = 124/437 (28%), Positives = 183/437 (41%), Gaps = 33/437 (7%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 IE MPAL M+EGTL +WLVK GD V+ G ++A +ET KA +E E EG + +++VP Sbjct: 3 IELLMPALSPTMEEGTLAKWLVKEGDTVNSGDLLAEIETDKATMEFEAVDEGIIGKILVP 62 Query: 62 VG-DTVEVGTVLATLLE-----------PGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXX 109 G + V+V T +A + E P + Sbjct: 63 EGTENVKVNTAIALIGEEGDDFSAAPAAPAEDAAAEEASPEAEEVTPSEAAPAAASSAPA 122 Query: 110 XXXXXXRHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXX 169 R + SP ARR+A+ +DL + G+GP G + DVE Sbjct: 123 APVTKDGGRIFASPLARRIAKDKGLDLSQIKGSGPHGRIVKVDVEGASAAPKSEAPTAKS 182 Query: 170 XXXXXXXXXXXXXXXQNKIAERAAQM--------------RKSIAAAMSRSKREIPHYYL 215 AE+ +M RK++AA ++ +K+ IPH+YL Sbjct: 183 EAPKAAAPAGGGAMPTGPSAEQVLKMYEGREFEEVKLNGMRKTVAARLTEAKQTIPHFYL 242 Query: 216 ADEILMEKSLNWLTTRNAQ---RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQA 272 +I ++ L + + N Q R + + Q + N W D Sbjct: 243 RRDIQLDALLKFRSQLNKQLEGRGV--KLSVNDFVIKACALALQAVPDANAVWAGDRMIK 300 Query: 273 ATGVHVGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTIT 332 V V +++ GGL P + D K L L ++ DL RAR G L E + Sbjct: 301 LKPSDVAVAVAV-DGGLFTPVLKDSDSKSLSALSAEMKDLATRARDGKLAPHEYVGGSFA 359 Query: 333 VTNLGDQGVDTVFGVIYPPQVAIVGFGKPAQRVCV-IDGGIRVVTTVQGTLAADHRASDG 391 ++NLG G++ VI PP AI+ G ++ V DG + V T + TL+ DHR DG Sbjct: 360 ISNLGMMGIENFDAVINPPHGAILAVGAGVKKPVVGADGELAVATVMSTTLSVDHRVIDG 419 Query: 392 HRGALFLAAINELLQQP 408 GA LAAI + L+ P Sbjct: 420 ALGAELLAAIKDNLENP 436 >tr|Q1GTS2|Q1GTS2_SPHAL Tax_Id=117207 SubName: Full=Dihydrolipoamide acetyltransferase, long form; EC=2.3.1.61;[Sphingopyxis alaskensis] Length = 436 Score = 161 bits (407), Expect = 2e-37 Identities = 121/430 (28%), Positives = 182/430 (42%), Gaps = 24/430 (5%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 IE KMPAL M+EGTL +WLVK GD+V G ++A +ET KA +E E EG + +++V Sbjct: 3 IELKMPALSPTMEEGTLAKWLVKEGDEVKSGDLLAEIETDKATMEFEAVDEGVISQILVA 62 Query: 62 VG-DTVEVGTVLATLLEPG------------AXXXXXXXXXXXKRXXXXXXXXXXXXXXX 108 G D V+VGTV+A + G A Sbjct: 63 EGTDGVKVGTVIAVIAGEGEDAGEAKATPAAAPAPVPAKDVAPAEAGAATVSAPPPAVLA 122 Query: 109 XXXXXXXRHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXX 168 R SP ARRLA +DL ++GTGP G + +D+E Sbjct: 123 SAGTTNVGDRIKASPLARRLAAEQGIDLKKLTGTGPGGRIVKADLEGAPTGAAASTAVAP 182 Query: 169 XXXXXXXXXXXXXXXXQNKIA---------ERAAQMRKSIAAAMSRSKREIPHYYLADEI 219 E+ + MRK+IA +S+S ++ PH YL +I Sbjct: 183 AQAGAAVGTAPAAAPEPAGPIPDFGIPHEDEKLSGMRKTIARRLSQSMQDAPHIYLTVDI 242 Query: 220 LMEKSLNWLTTRNAQ-RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHV 278 ++ L NA S + +R + N + D + + Sbjct: 243 RLDALLKLRGELNASLESRGVKLSVNDMLIKALAVALERVPQCNVSFGGDVMRFYKRADI 302 Query: 279 GVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGD 338 V +S+ GG L+ P I D K L ++ ++ +L RA+ G L+ E T +++N+G Sbjct: 303 SVAVSIPGG-LITPIITDAGAKSLSKISTEMAELAGRAKEGKLQPHEYQGGTASISNMGM 361 Query: 339 QGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFL 398 G+ VI PPQ I+ G +R V+D + + T + T + DHRA DG GAL + Sbjct: 362 MGIKQFTAVINPPQAMIMAIGAGEKRPYVVDDALAIATVMSATGSFDHRAIDGADGALLM 421 Query: 399 AAINELLQQP 408 EL++ P Sbjct: 422 KTFKELVESP 431 >sp|Q1RJT3|ODP2_RICBR Tax_Id=336407 (pdhC)RecName: Full=Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; EC=2.3.1.12; AltName: Full=E2; AltName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex;[Rickettsia bellii] Length = 418 Score = 160 bits (406), Expect = 2e-37 Identities = 116/433 (26%), Positives = 182/433 (42%), Gaps = 45/433 (10%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I+ MPAL M EG L WL K GDK++ G+++A +ET KA +E+E EGT+ ++++P Sbjct: 3 IKLLMPALSPTMTEGNLARWLKKEGDKINPGEVIAEIETDKATMEVEAVDEGTLAKIIIP 62 Query: 62 VGD-TVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRH--- 117 G V V +++A L+E G Sbjct: 63 QGSQNVPVNSLIAVLIEEGEELSGIEEFIAKNNSNSPKKEEISKPAETIAPQNVKEENIT 122 Query: 118 --------RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXX 169 + + SP A+RLA+ +V ++ + G+GP G + DV Sbjct: 123 TASDQNNIKVFASPLAKRLAKIQNVRIEEIKGSGPHGRIIKQDV---------------- 166 Query: 170 XXXXXXXXXXXXXXXQNKIAERAAQ---------MRKSIAAAMSRSKREIPHYYLADEIL 220 NKI R + +RK IA + SK+ +PH+YL+ E Sbjct: 167 -----LSHKGGSKALSNKIVSRNPEEYRLAPNNNIRKIIAKRLLESKQTVPHFYLSIECN 221 Query: 221 MEKSLNWLTTRNAQ--RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHV 278 ++K L+ N + + Q N W DD + V + Sbjct: 222 VDKLLDIREDINKSFGDDKSAKISVNDFIILAVAKALQEVPNANASWGDDAIRYYNNVDI 281 Query: 279 GVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGD 338 V +++ G LV P I + K + +L ++ L+ +AR L E T++NLG Sbjct: 282 SVAVAIENG-LVTPIIRNADQKNIVDLSSEMKGLIKKARENKLTPEEFQGGGFTISNLGM 340 Query: 339 QGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFL 398 G+ +I PPQ I+G G ++R V + I + T + TL+ADHR DG GA FL Sbjct: 341 YGIKNFNAIINPPQSCIMGVGSSSKRAIVKNDQISIATIMDVTLSADHRVVDGAVGAEFL 400 Query: 399 AAINELLQQPDLL 411 AA ++ P L+ Sbjct: 401 AAFKRFIESPALM 413 >tr|A8TL71|A8TL71_9PROT Tax_Id=331869 SubName: Full=Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzyme;[alpha proteobacterium BAL199] Length = 429 Score = 160 bits (404), Expect = 4e-37 Identities = 117/424 (27%), Positives = 177/424 (41%), Gaps = 19/424 (4%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I MPAL M EG L +W VK GD +S G ++A +ET KA +E+E +EG + ++VV Sbjct: 3 ISILMPALSPTMSEGNLAKWHVKEGDTISAGDVIAEIETDKATMEVEAVEEGKIGKIVVA 62 Query: 62 VG-DTVEVGTVLATLLEPG---------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXX 111 G + V V V+A LLE G Sbjct: 63 EGTEGVAVNAVIAWLLEEGESAGDIPSDGGHAPAPAAEAATPQPAAKAEPAKTDAPAASA 122 Query: 112 XXXXRHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXXX 171 R + SP A+R+A+ +DL AV G+GP G + +D+E Sbjct: 123 PKASEGRVFASPLAKRMAEQAGIDLGAVKGSGPNGRIVKADIEAAVSGGAPKKAVAAAAP 182 Query: 172 XXXXXXXXXXXXXQNKIAERA-------AQMRKSIAAAMSRSKREIPHYYLADEILMEKS 224 + + MRK IA ++ SK+ PH+YL + +++ Sbjct: 183 TPAAAAPSLGQAPSADVPGMPEYDEVPNSGMRKVIAKRLTESKQFAPHFYLTIDCEIDEL 242 Query: 225 LNWLTTRNAQRSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVGISL 284 L N + + ++ N W + + V + V +++ Sbjct: 243 LKVRKDLNTKGD-DFKLSVNDLVIRAAALALKKVPAANASWTEKAIRIYKQVDISVAVAI 301 Query: 285 RGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTV 344 GL+ P I D K L ++ ++ DL RAR L+ E T +++NLG G+ Sbjct: 302 -DDGLITPVIKDAGSKGLKQISAEMKDLATRARDRKLKPEEFQGGTFSISNLGMFGIKDF 360 Query: 345 FGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINEL 404 VI PPQ AI+ G QR V DG + + T + TL+ DHR DG GA FLAA +L Sbjct: 361 AAVINPPQGAILAVGAGEQRAVVKDGALAIATVMSCTLSVDHRVVDGAIGAQFLAAFKKL 420 Query: 405 LQQP 408 ++ P Sbjct: 421 VEDP 424 >sp|Q4ULG1|ODP2_RICFE Tax_Id=42862 (pdhC)RecName: Full=Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; EC=2.3.1.12; AltName: Full=E2; AltName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex;[Rickettsia felis] Length = 412 Score = 159 bits (402), Expect = 6e-37 Identities = 117/434 (26%), Positives = 188/434 (43%), Gaps = 50/434 (11%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I+ MP L M EG L WL K GDKV+ G+++A +ET KA +E+E EG + ++V+P Sbjct: 3 IKILMPVLSPTMTEGNLARWLKKEGDKVNPGEVIAEIETDKATMEVEAVDEGILAKIVIP 62 Query: 62 VGD-TVEVGTVLATLLEPG-------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXX 113 V V +++A L E G A + Sbjct: 63 QNSQNVPVNSLIAVLSEEGEEKTDIDAFIAKNNNVSPSPKTDANLPKPHENIAKVEEQVA 122 Query: 114 XXRH---RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 +H + + SP A+RLA+ ++ L++V G+GP G + D+ Sbjct: 123 VIKHDASKIFASPLAKRLAKMGNIRLESVKGSGPHGRIVKQDI----------------- 165 Query: 171 XXXXXXXXXXXXXXQNKIAERAAQ---------MRKSIAAAMSRSKREIPHYYLADEILM 221 NKI R + +RK IA + SK+ +PH+YL+ E + Sbjct: 166 ------LSYTPSTVHNKIVSRNPEEYRLVPNNNIRKIIAKRLLESKQTVPHFYLSIECNV 219 Query: 222 EKSLNWLTTRNAQRSITE----RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVH 277 +K L+ + +S +E R Q N W +D + V Sbjct: 220 DKLLD--IREDINKSFSEDKSTRISVNDFIILAVAKALQELPNANASWGEDAIRYHNNVD 277 Query: 278 VGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLG 337 + V +++ G LV P + + K + EL ++ +L+ +A+ L E T++NLG Sbjct: 278 ISVAVAIENG-LVTPIVKNANQKNIIELSREMKELIKKAKDNKLTPEEFQGGGFTISNLG 336 Query: 338 DQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALF 397 G+ +I PPQ I+G G A+R V + + + T + TL+ADHR DG GA F Sbjct: 337 MYGIKNFNAIINPPQSCIMGVGASAKRAIVKNDQVTIATIMDVTLSADHRVVDGAVGAEF 396 Query: 398 LAAINELLQQPDLL 411 LAA + ++ P L+ Sbjct: 397 LAAFKKFIESPALM 410 >tr|C1YP51|C1YP51_NOCDA Tax_Id=446468 SubName: Full=Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component;[Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length = 436 Score = 159 bits (401), Expect = 8e-37 Identities = 119/432 (27%), Positives = 183/432 (42%), Gaps = 25/432 (5%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M E +MP L M+EG ++ W+ GDKV+ G ++ +ET KA +E E +++G + + V Sbjct: 1 MSEIQMPRLSDTMEEGVISTWVKNVGDKVASGDVLVEIETDKAVMEYEAYEDGYLVKQSV 60 Query: 61 PVGDTVEVGTVLATLL---------------EPGAXXXXXXXXXXXKRXXXXXXXXXXXX 105 G+TV +G V+ + EP A + Sbjct: 61 SEGETVPIGAVIGVIADSPDAVPEDSGDGGSEPEAAPAEEEQGEKAEEIQEAAEGTEAES 120 Query: 106 XXXXXXXXXXRHRR-WVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXX 164 R SP ARRLA+ +D++ + G+GP+G + +D+E Sbjct: 121 AGESAASSGDGAARPRTSPLARRLAKEYGLDINRIQGSGPKGRIVRADIEAAREGGAAEQ 180 Query: 165 XXXXXXXXXXXXXXXXXXXXQNKIAE-------RAAQMRKSIAAAMSRSKREIPHYYLAD 217 + + + +RK IA ++ SK+ +PH+YL Sbjct: 181 AAPAAQPKEEAKPAAEKAATAPAFDDGRASEELKVSNVRKVIARRLTESKQTVPHFYLRR 240 Query: 218 EILMEKSLNWLTTRNAQRSITE-RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGV 276 I E + N Q S T + + N W DD V Sbjct: 241 TIDAEALKAFRAQINEQLSSTGVKVSFNDLIVKASATALKLHPAVNTSWVDDKLLQHHRV 300 Query: 277 HVGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNL 336 +VGV +++ GLV P +HD L E+ +L +AR G L+ EMS T +V+NL Sbjct: 301 NVGVAVAV-DAGLVVPVLHDTDKATLSEISTRTRELAGKARDGKLKPQEMSGGTFSVSNL 359 Query: 337 GDQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGAL 396 G GVD+ VI PP+ AI+ G Q V+DG + V + L+ DHRA DG GA Sbjct: 360 GMFGVDSFSAVINPPEAAILAVGAMRQEPVVVDGEVVVRNRISLELSVDHRAVDGAVGAA 419 Query: 397 FLAAINELLQQP 408 FL + E+L++P Sbjct: 420 FLKDLAEILEEP 431 >tr|A8F1S0|A8F1S0_RICM5 Tax_Id=416276 (pdhC)SubName: Full=Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase;[Rickettsia massiliae] Length = 412 Score = 158 bits (400), Expect = 1e-36 Identities = 118/434 (27%), Positives = 188/434 (43%), Gaps = 50/434 (11%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I+ MPAL M EG L WL K GDKV+ G+++A +ET KA +E+E EG + ++V+P Sbjct: 3 IKILMPALSPTMTEGNLARWLKKEGDKVNPGEVIAEIETDKATMEVEAVDEGILAKIVIP 62 Query: 62 VGD-TVEVGTVLATLLEPG-------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXX 113 V V +++A L E G A + Sbjct: 63 QNSQNVPVNSLIAVLSEEGEEKTDIDAFIAKNNSVSPSPKTDANLLKPHENIANVEEQVT 122 Query: 114 XXRH---RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 +H + + SP A+RLA+ ++ ++V G+GP G + D+ Sbjct: 123 VIKHDASKIFASPLAKRLAKMGNIRFESVKGSGPHGRIVKQDI----------------- 165 Query: 171 XXXXXXXXXXXXXXQNKIAERAAQ---------MRKSIAAAMSRSKREIPHYYLADEILM 221 NKI R + +RK IA + SK+ +PH+YL+ E + Sbjct: 166 ------LSYTPSTAHNKIVSRNPEEYRLVPNNNIRKIIAKRLFESKQTVPHFYLSIECNV 219 Query: 222 EKSLNWLTTRNAQRSITE----RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVH 277 +K L+ + +S +E R Q N W +D + V Sbjct: 220 DKLLD--IREDINKSFSEDKSTRISVNDFIILAVAKALQEVPNANASWGEDAIRYYNNVD 277 Query: 278 VGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLG 337 + V +++ G LV P + + K + EL ++ +L+ +A+ L E T++NLG Sbjct: 278 ISVAVAIENG-LVTPIVKNANQKNILELSREMKELIKKAKDNKLTPEEFQGGGFTISNLG 336 Query: 338 DQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALF 397 G+ +I PPQ I+G G A+R V + I + T + TL+ADHR DG GA F Sbjct: 337 MYGIKNFNAIINPPQGCIMGVGASAKRAIVKNDQITIATIMDVTLSADHRVVDGAVGAEF 396 Query: 398 LAAINELLQQPDLL 411 LAA + ++ P L+ Sbjct: 397 LAAFKKFIESPALM 410 >tr|Q47KD8|Q47KD8_THEFY Tax_Id=269800 SubName: Full=Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase;[Thermobifida fusca] Length = 431 Score = 158 bits (399), Expect = 1e-36 Identities = 121/427 (28%), Positives = 183/427 (42%), Gaps = 20/427 (4%) Query: 1 MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVV 60 M E MP L M+EG ++ W+ + GDKVS G ++ +ET KA +E E +++G + + V Sbjct: 1 MSEIYMPRLSDTMEEGVISSWVKQVGDKVSVGDVLVEIETDKAVMEYEAYEDGYLVQQTV 60 Query: 61 PVGDTVEVGTVLATLLEP------------GAXXXXXXXXXXXKRXXXXXXXXXXXXXXX 108 G+TV +G V+ + + GA Sbjct: 61 REGETVPIGAVIGVIADSPDAVPAAPEGGEGAEQKAEEPQQPAPAAQEAKEEQPTVPAPA 120 Query: 109 XXXXXXXRHRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXX 168 + R SP ARRLA+ +D+ + G+GP+G V +DVE Sbjct: 121 APAEQGGKPRPLSSPLARRLAREYGLDITKIQGSGPKGRVVRADVEAAAQQKREQEAAAP 180 Query: 169 XXXXXXXXXXXXXXXXQNKIAERAAQ------MRKSIAAAMSRSKREIPHYYLADEILME 222 RA++ +R+ IA ++++K+EIPH+YL I E Sbjct: 181 QPAAAKAPAPAAAPPQPEFEDLRASEEVPVTNIRRVIARRLTQAKQEIPHFYLRRRIDAE 240 Query: 223 KSLNWLTTRNAQRSITE-RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVGVG 281 + N Q + T + + E N W DD ++VG+ Sbjct: 241 ALREFRAQINEQLAPTGVKVSVNDLIVKAVATVLRDHPEVNSSWVDDKLLRHKRINVGIA 300 Query: 282 ISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQGV 341 +++ GLV P +HD L E+ LV +AR G L +MS T +V+NLG GV Sbjct: 301 VAV-DTGLVVPVLHDADTLALSEVARRSRALVEKARDGKLSPQDMSGGTFSVSNLGMFGV 359 Query: 342 DTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAI 401 ++ VI PP+ AI+ G Q V DG I T+ L+ DHRA DG GA FL + Sbjct: 360 ESFSAVINPPEAAILAVGAMQQEPVVRDGEIVARHTIALELSVDHRAVDGAVGAAFLKDL 419 Query: 402 NELLQQP 408 E+L+ P Sbjct: 420 AEVLESP 426 >tr|C4K0D0|C4K0D0_RICPU Tax_Id=562019 SubName: Full=Branched-chain alpha-keto acid dehydrogenase subunit E2;[Rickettsia peacockii] Length = 412 Score = 157 bits (398), Expect = 2e-36 Identities = 118/434 (27%), Positives = 187/434 (43%), Gaps = 50/434 (11%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I+ MPAL M EG L WL K GDKV+ G+++A +ET KA +E+E EG + ++V+P Sbjct: 3 IKILMPALSPTMTEGNLARWLKKEGDKVNPGEVIAEIETDKATMEVEAVDEGILAKIVIP 62 Query: 62 VGD-TVEVGTVLATLLEPG-------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXX 113 V V +++A L E G A + Sbjct: 63 QNSQNVPVNSLIAVLSEEGEEKTDIDAFIAKNNSVSPSPKTDANLPKPHENITNVEEQVT 122 Query: 114 XXRH---RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 +H + + SP A+RLA+ ++ ++V G+GP G + D+ Sbjct: 123 VIKHDASKIFASPLAKRLAKMRNIRFESVKGSGPHGRIVKQDI----------------- 165 Query: 171 XXXXXXXXXXXXXXQNKIAERAAQ---------MRKSIAAAMSRSKREIPHYYLADEILM 221 NKI R + +RK IA + SK+ +PH+YL+ E + Sbjct: 166 ------LSYTPNTAHNKIVSRNPEEYRLVPNNNIRKIIAKRLLESKQTVPHFYLSIECNV 219 Query: 222 EKSLNWLTTRNAQRSITE----RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVH 277 +K L+ + +S +E R Q N W +D + V Sbjct: 220 DKLLD--IREDINKSFSEDKSTRISVNDFIILAVAKALQEVPNANASWGEDAIRYYNNVD 277 Query: 278 VGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLG 337 + V +++ G LV P + + K + EL ++ L+ +A+ L E T++NLG Sbjct: 278 ISVAVAIENG-LVTPIVKNANQKNILELSREMKALIKKAKDNKLTPEEFQGGGFTISNLG 336 Query: 338 DQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALF 397 G+ +I PPQ I+G G A+R V + I + T + TL+ADHR DG GA F Sbjct: 337 MYGIKNFNAIINPPQSCIMGVGASAKRAIVKNDQITIATIMDVTLSADHRVVDGAVGAEF 396 Query: 398 LAAINELLQQPDLL 411 LAA + ++ P L+ Sbjct: 397 LAAFKKFIESPVLM 410 >tr|B5KBW7|B5KBW7_9RHOB Tax_Id=391616 SubName: Full=Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; EC=2.3.1.12;[Octadecabacter antarcticus 238] Length = 446 Score = 157 bits (398), Expect = 2e-36 Identities = 124/446 (27%), Positives = 182/446 (40%), Gaps = 46/446 (10%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 IE MPAL M+EGTL +WLVK GD+V G ++A +ET KA +E E +EG V +L+V Sbjct: 3 IEILMPALSPTMEEGTLAKWLVKEGDEVKSGDLIAEIETDKATMEFEAVEEGIVSKLLVA 62 Query: 62 VG-DTVEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXR---- 116 G + V+V T + + E G + Sbjct: 63 EGTEGVKVNTPICIIGEEGEDMSSAPAPKSKESVKDQGDTLSADKAESAAPASEPAAAPA 122 Query: 117 ------------HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXX 164 R + +P ARR+A+ +DL + G+GP G + +DVE+ Sbjct: 123 SAPKAAPAAKDGSRLFATPLARRIAKDKGLDLATIKGSGPHGRIIKADVENASAQPAAAL 182 Query: 165 XXXXXXXXXXXXXXXXXXXXQNKIAERAAQM--------------RKSIAAAMSRSKREI 210 E+ +M RK IA+ ++ +K+ + Sbjct: 183 AAAAAPASAAPAAATGAIAATGPSTEQVIKMYEGRTFKEVKLDGMRKIIASRLTEAKQTV 242 Query: 211 PHYYLADEILMEKSLNW-------LTTRNAQRSITERXXXXXXXXXXXXXXXQRFGEFNG 263 PH+YL +I ++ L + L R + S+ + Q E N Sbjct: 243 PHFYLRRDIELDALLKFRSQLNKTLEPRGVKLSVND------FIIKACALALQEIPEANA 296 Query: 264 FWRDDGFQAATGVHVGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRS 323 W D T V V +++ GG L P + D K L L + DL ARAR L Sbjct: 297 VWAGDRVLQMTASDVAVAVAIEGG-LFTPVLQDAETKSLSALSAQMKDLAARARDRKLAP 355 Query: 324 SEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGFGKPAQRVCV-IDGGIRVVTTVQGTL 382 E + ++NLG G+D +I PP AI+ G A++ V DG I+V T + TL Sbjct: 356 HEYQGGSFAISNLGMFGIDNFDAIINPPHSAILAVGAGAKKPIVGADGDIKVATVMSTTL 415 Query: 383 AADHRASDGHRGALFLAAINELLQQP 408 + DHR DG GA L AI L+ P Sbjct: 416 SVDHRVIDGAMGANLLNAIKANLENP 441 >tr|Q3J3J1|Q3J3J1_RHOS4 Tax_Id=272943 (pdhB)SubName: Full=Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex; EC=2.3.1.12;[Rhodobacter sphaeroides] Length = 442 Score = 157 bits (397), Expect = 2e-36 Identities = 126/435 (28%), Positives = 182/435 (41%), Gaps = 30/435 (6%) Query: 3 EFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPV 62 E MPAL M+EGTL +WL K GD+V G I+A +ET KA +E E EG + ++++ Sbjct: 4 EILMPALSPTMEEGTLAKWLKKEGDEVRSGDIIAEIETDKATMEFEAVDEGILGKILIAE 63 Query: 63 GDT-VEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXR----- 116 G V+V T +A L+E G + + Sbjct: 64 GTAGVKVNTPIAVLVEEGESVDAVSSAKVPEPQEPADEAAPAQGAPKEAPAPAAKAPAAQ 123 Query: 117 ------HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 R + SP ARR+A+ +DL AV G+GP+G + +DVE Sbjct: 124 AARSEGERVFASPLARRIAKEKGIDLAAVQGSGPRGRIVKADVEGAQPSAAPAAKADAAA 183 Query: 171 XXXXXXXXXXXXXXQ---------NKIAERAAQ------MRKSIAAAMSRSKREIPHYYL 215 A+R + MRK+IAA +S +K+ IPH+YL Sbjct: 184 PKAEAPAAAAAPVAAPAASAASVAKLFADRDYEEVTLDGMRKTIAARLSEAKQTIPHFYL 243 Query: 216 ADEILMEKSLNWLTTRNAQ-RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAAT 274 E+ ++ + + NA+ S + Q+ N W D Sbjct: 244 RREVALDALMAFRADLNAKLESRGVKLSVNDFIIKACAVALQQVPNANAVWAGDRILRLK 303 Query: 275 GVHVGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVT 334 V V +++ GG L P + D K L L ++ DL ARAR L E + ++ Sbjct: 304 PSDVAVAVAIEGG-LFTPVLRDAHQKSLSALSAEMKDLAARARTKKLAPHEYQGGSFAIS 362 Query: 335 NLGDQGVDTVFGVIYPPQVAIVGFGKPAQRVCV-IDGGIRVVTTVQGTLAADHRASDGHR 393 NLG GV+ VI PP +I+ G ++ V DG I T + TL+ DHR DG Sbjct: 363 NLGMFGVENFDAVINPPHGSILAVGAGIRKPVVGKDGAITTATMMSMTLSVDHRVIDGAL 422 Query: 394 GALFLAAINELLQQP 408 GA FL AI E L+ P Sbjct: 423 GAEFLKAIVENLENP 437 >tr|A3PIU1|A3PIU1_RHOS1 Tax_Id=349101 SubName: Full=Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; EC=2.3.1.61;[Rhodobacter sphaeroides] Length = 442 Score = 157 bits (397), Expect = 2e-36 Identities = 126/435 (28%), Positives = 182/435 (41%), Gaps = 30/435 (6%) Query: 3 EFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPV 62 E MPAL M+EGTL +WL K GD+V G I+A +ET KA +E E EG + ++++ Sbjct: 4 EILMPALSPTMEEGTLAKWLKKEGDEVRSGDIIAEIETDKATMEFEAVDEGILGKILIAE 63 Query: 63 GDT-VEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXR----- 116 G V+V T +A L+E G + + Sbjct: 64 GTAGVKVNTPIAVLVEEGESVDAVSSAKVPEPQEPADEAAPAQEAPKAAPAPAAKAPEAQ 123 Query: 117 ------HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 R + SP ARR+A+ +DL AV G+GP+G + +DVE Sbjct: 124 AARSEGERVFASPLARRIAKEKGIDLAAVQGSGPRGRIVKADVEGARPSAAPAAKADVAA 183 Query: 171 XXXXXXXXXXXXXXQ---------NKIAERAAQ------MRKSIAAAMSRSKREIPHYYL 215 A+R + MRK+IAA +S +K+ IPH+YL Sbjct: 184 PKAEAPAAAAAPVAAPAASAASVAKLFADRDYEEVTLDGMRKTIAARLSEAKQTIPHFYL 243 Query: 216 ADEILMEKSLNWLTTRNAQ-RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAAT 274 E+ ++ + + NA+ S + Q+ N W D Sbjct: 244 RREVALDALMAFRADLNAKLESRGVKLSVNDFIIKACAVALQQVPNANAVWAGDRILRLK 303 Query: 275 GVHVGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVT 334 V V +++ GG L P + D K L L ++ DL ARAR L E + ++ Sbjct: 304 PSDVAVAVAIEGG-LFTPVLRDAHQKSLSALSAEMKDLAARARTKKLAPHEYQGGSFAIS 362 Query: 335 NLGDQGVDTVFGVIYPPQVAIVGFGKPAQRVCV-IDGGIRVVTTVQGTLAADHRASDGHR 393 NLG GV+ VI PP +I+ G ++ V DG I T + TL+ DHR DG Sbjct: 363 NLGMFGVENFDAVINPPHGSILAVGAGIRKPVVGKDGAITTATMMSMTLSVDHRVIDGAL 422 Query: 394 GALFLAAINELLQQP 408 GA FL AI E L+ P Sbjct: 423 GAEFLKAIVENLENP 437 >tr|B0BXT8|B0BXT8_RICRO Tax_Id=452659 SubName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; EC=2.3.1.12;[Rickettsia rickettsii] Length = 412 Score = 157 bits (396), Expect = 3e-36 Identities = 118/434 (27%), Positives = 187/434 (43%), Gaps = 50/434 (11%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I+ MPAL M EG L WL K GDKV+ G+++A +ET KA +E+E EG + ++V+P Sbjct: 3 IKILMPALSPTMTEGNLARWLKKEGDKVNPGEVIAEIETDKATMEVEAVDEGILAKIVIP 62 Query: 62 VGD-TVEVGTVLATLLEPG-------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXX 113 V V +++A L E G A + Sbjct: 63 QNSQNVPVNSLIAVLSEEGEEKTDIDAFIAKNNSVSPSPKTDANLLKPHENITNVEEQVT 122 Query: 114 XXRH---RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 +H + + SP A+RLA+ ++ ++V G+GP G + D+ Sbjct: 123 VIKHDASKIFASPLAKRLAKMRNIRFESVKGSGPHGRIVKQDI----------------- 165 Query: 171 XXXXXXXXXXXXXXQNKIAERAAQ---------MRKSIAAAMSRSKREIPHYYLADEILM 221 NKI R + +RK IA + SK+ +PH+YL+ E + Sbjct: 166 ------LSYTPSTAHNKIVSRNPEEYRLVPNNNIRKIIAKRLLESKQTVPHFYLSIECNV 219 Query: 222 EKSLNWLTTRNAQRSITE----RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVH 277 +K L+ + +S +E R Q N W +D + V Sbjct: 220 DKLLD--IREDINKSFSEDKSTRISVNDFIILAVAKALQEVPNANASWGEDAIRYYNNVD 277 Query: 278 VGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLG 337 + V +++ G LV P + + K + EL ++ L+ +A+ L E T++NLG Sbjct: 278 ISVAVAIENG-LVTPIVKNANQKNILELSREMKALIKKAKDNKLTPEEFQGGGFTISNLG 336 Query: 338 DQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALF 397 G+ +I PPQ I+G G A+R V + I + T + TL+ADHR DG GA F Sbjct: 337 MYGIKNFNAIINPPQSCIMGVGAIAKRAIVKNDQITIATIMDVTLSADHRVVDGAVGAEF 396 Query: 398 LAAINELLQQPDLL 411 LAA + ++ P L+ Sbjct: 397 LAAFKKFIESPVLM 410 >tr|A8GSC6|A8GSC6_RICRS Tax_Id=392021 SubName: Full=Branched-chain alpha-keto acid dehydrogenase subunit E2;[Rickettsia rickettsii] Length = 412 Score = 157 bits (396), Expect = 3e-36 Identities = 118/434 (27%), Positives = 187/434 (43%), Gaps = 50/434 (11%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I+ MPAL M EG L WL K GDKV+ G+++A +ET KA +E+E EG + ++V+P Sbjct: 3 IKILMPALSPTMTEGNLARWLKKEGDKVNPGEVIAEIETDKATMEVEAVDEGILAKIVIP 62 Query: 62 VGD-TVEVGTVLATLLEPG-------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXX 113 V V +++A L E G A + Sbjct: 63 QNSQNVPVNSLIAVLSEEGEEKTDIDAFIAKNNSVSPSPKTDANLLKPHESITNVEEQVT 122 Query: 114 XXRH---RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 +H + + SP A+RLA+ ++ ++V G+GP G + D+ Sbjct: 123 VIKHDASKIFASPLAKRLAKMRNIRFESVKGSGPHGRIVKQDI----------------- 165 Query: 171 XXXXXXXXXXXXXXQNKIAERAAQ---------MRKSIAAAMSRSKREIPHYYLADEILM 221 NKI R + +RK IA + SK+ +PH+YL+ E + Sbjct: 166 ------LSYTPSTAHNKIVSRNPEEYRLVPNNNIRKIIAKRLLESKQTVPHFYLSIECNV 219 Query: 222 EKSLNWLTTRNAQRSITE----RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVH 277 +K L+ + +S +E R Q N W +D + V Sbjct: 220 DKLLD--IREDINKSFSEDKSTRISVNDFIILAVAKALQEVPNANASWGEDAIRYYNNVD 277 Query: 278 VGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLG 337 + V +++ G LV P + + K + EL ++ L+ +A+ L E T++NLG Sbjct: 278 ISVAVAIENG-LVTPIVKNANQKNILELSREMKALIKKAKDNKLTPEEFQGGGFTISNLG 336 Query: 338 DQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALF 397 G+ +I PPQ I+G G A+R V + I + T + TL+ADHR DG GA F Sbjct: 337 MYGIKNFNAIINPPQSCIMGVGAIAKRAIVKNDQITIATIMDVTLSADHRVVDGAVGAEF 396 Query: 398 LAAINELLQQPDLL 411 LAA + ++ P L+ Sbjct: 397 LAAFKKFIESPVLM 410 >tr|C3PNM9|C3PNM9_RICAE Tax_Id=347255 (pdhC)SubName: Full=Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; EC=2.3.1.12;[Rickettsia africae] Length = 412 Score = 156 bits (395), Expect = 4e-36 Identities = 117/432 (27%), Positives = 184/432 (42%), Gaps = 46/432 (10%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I+ MPAL M EG L WL K GDKV+ G+++A +ET KA +E+E EG + ++V+P Sbjct: 3 IKILMPALSPTMTEGNLARWLKKEGDKVNPGEVIAEIETDKATMEVEAVDEGILAKIVIP 62 Query: 62 VGD-TVEVGTVLATLLEPG-------AXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXX 113 V V +++A L E G A + Sbjct: 63 QNSQNVPVNSLIAVLSEEGEEKTDIDAFIAKNNSVSPSPKTDANLPKPHENIANVEEQVT 122 Query: 114 XXRH---RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 +H + + SP A+RLA+ ++ ++V G+GP G + D+ Sbjct: 123 VIKHDASKIFASPLAKRLAKMRNIRFESVKGSGPHGRIVKQDI----------------- 165 Query: 171 XXXXXXXXXXXXXXQNKIAERAAQ---------MRKSIAAAMSRSKREIPHYYLADEILM 221 NKI R + +RK IA + SK+ +PH+YL+ E + Sbjct: 166 ------LSYTPSTAHNKIVSRNPEEYRLVPNNNIRKIIAKRLLESKQTVPHFYLSIECNV 219 Query: 222 EKSLNWLTTRNA--QRSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVHVG 279 +K L+ N + R Q N W +D + V + Sbjct: 220 DKLLDIREDINKFFSEDKSTRISVNDFIILAVAKALQEVPNANASWGEDAIRYYNNVDIS 279 Query: 280 VGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLGDQ 339 V +++ G LV P + + K + EL ++ L+ +A+ L E T++NLG Sbjct: 280 VAVAIENG-LVTPIVKNANQKNILELSREMKALIKKAKDNKLTPEEFQGGGFTISNLGMY 338 Query: 340 GVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLA 399 G+ +I PPQ I+G G A+R V + I + T + TL+ADHR DG GA FLA Sbjct: 339 GIKNFNAIINPPQSCIMGVGASAKRAIVKNDQITIATIMDVTLSADHRVVDGAVGAEFLA 398 Query: 400 AINELLQQPDLL 411 A + ++ P L+ Sbjct: 399 AFKKFIESPVLM 410 >tr|B9KQT2|B9KQT2_RHOSK Tax_Id=557760 SubName: Full=Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase;[Rhodobacter sphaeroides] Length = 442 Score = 156 bits (395), Expect = 4e-36 Identities = 126/435 (28%), Positives = 182/435 (41%), Gaps = 30/435 (6%) Query: 3 EFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVPV 62 E MPAL M+EGTL +WL K GD+V G I+A +ET KA +E E EG + ++++ Sbjct: 4 EILMPALSPTMEEGTLAKWLKKEGDEVRSGDIIAEIETDKATMEFEAVDEGILGKILIAE 63 Query: 63 GDT-VEVGTVLATLLEPGAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXXXXRH---- 117 G V+V T +A L+E G + + Sbjct: 64 GTAGVKVNTPIAVLVEEGESVDAVSSAKVPEPQEPADEAAPAQGAPKAAPAPAAKAPEAQ 123 Query: 118 -------RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 R + SP ARR+A+ +DL AV G+GP+G + +DVE Sbjct: 124 AARSEGGRVFASPLARRIAKEKGIDLAAVQGSGPRGRIVKADVEGAQPVAAPAAKADAAA 183 Query: 171 XXXXXXXXXXXXXXQ---------NKIAERAAQ------MRKSIAAAMSRSKREIPHYYL 215 A+R + MRK+IAA +S +K+ IPH+YL Sbjct: 184 PKAEAPAAAAAPVAAPAASAASVAKLFADRDYEEVTLDGMRKTIAARLSEAKQTIPHFYL 243 Query: 216 ADEILMEKSLNWLTTRNAQ-RSITERXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAAT 274 E+ ++ + + NA+ S + Q+ N W D Sbjct: 244 RREVALDALMAFRADLNAKLESRGVKLSVNDFIIKACAVALQQVPNANAVWAGDRILRLK 303 Query: 275 GVHVGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVT 334 V V +++ GG L P + D K L L ++ DL ARAR L E + ++ Sbjct: 304 PSDVAVAVAIEGG-LFTPVLRDAHQKSLSALSAEMKDLAARARTKKLAPHEYQGGSFAIS 362 Query: 335 NLGDQGVDTVFGVIYPPQVAIVGFGKPAQRVCV-IDGGIRVVTTVQGTLAADHRASDGHR 393 NLG GV+ VI PP +I+ G ++ V DG I T + TL+ DHR DG Sbjct: 363 NLGMFGVENFDAVINPPHGSILAVGAGIRKPVVGKDGAITTATMMSMTLSVDHRVIDGAL 422 Query: 394 GALFLAAINELLQQP 408 GA FL AI E L+ P Sbjct: 423 GAEFLKAIVENLENP 437 >tr|A8GNQ3|A8GNQ3_RICAH Tax_Id=293614 SubName: Full=Branched-chain alpha-keto acid dehydrogenase subunit E2;[Rickettsia akari] Length = 412 Score = 156 bits (395), Expect = 4e-36 Identities = 119/434 (27%), Positives = 187/434 (43%), Gaps = 50/434 (11%) Query: 2 IEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIECWQEGTVDELVVP 61 I+ MPAL M G L WL K GDKV+ G+++A +ET KA +E+E EG + ++V+P Sbjct: 3 IKILMPALSPTMTAGNLARWLKKEGDKVNPGEVIAEIETDKATMEVEAVDEGILAKIVIP 62 Query: 62 VGD-TVEVGTVLATLLEP-------GAXXXXXXXXXXXKRXXXXXXXXXXXXXXXXXXXX 113 V V +++A L E A + Sbjct: 63 QNSQNVPVNSLIAVLSEAREEKADIDAFIAKNNNVSPSPKPDTNLPKHHENIAKVEEQVA 122 Query: 114 XXRH---RRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHXXXXXXXXXXXXXXX 170 +H + + SP A+RLA+ ++ L++V G+GP G + DV Sbjct: 123 VIKHDTSKIFASPLAKRLAKMGNIKLESVKGSGPHGRIVKQDV----------------- 165 Query: 171 XXXXXXXXXXXXXXQNKIAERAAQ---------MRKSIAAAMSRSKREIPHYYLADEILM 221 NKI R + +RK IA + SK+ +PH+YL+ E + Sbjct: 166 ------LSYTPSTVHNKIVSRNPEEYRLVPNNNIRKIIAKRLLESKQTVPHFYLSIECNV 219 Query: 222 EKSLNWLTTRNAQRSITE----RXXXXXXXXXXXXXXXQRFGEFNGFWRDDGFQAATGVH 277 +K L+ + +S +E R Q N WR+D + V Sbjct: 220 DKLLD--IREDINKSFSEDKATRISVNDFIILAVAKALQAVPNANASWREDAIRYYNNVD 277 Query: 278 VGVGISLRGGGLVAPAIHDVADKKLDELMGDLTDLVARARAGSLRSSEMSDPTITVTNLG 337 + V +++ G LV P + + K + E+ ++ L+ +A+ L E T++NLG Sbjct: 278 ISVAVAIENG-LVTPIVKNANQKNIIEISREMKKLIKKAKDNKLTPEEFQGGGFTISNLG 336 Query: 338 DQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALF 397 GV +I PPQ I+G G A+R V + I + T + TL+ADHR DG GA F Sbjct: 337 MYGVKNFNAIINPPQSCIMGVGASAKRAIVKNDQITIETIMDVTLSADHRVVDGAVGAEF 396 Query: 398 LAAINELLQQPDLL 411 LAA + ++ P L+ Sbjct: 397 LAAFKKFIESPALM 410 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.318 0.134 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 2,399,384,395 Number of extensions: 80833220 Number of successful extensions: 245194 Number of sequences better than 10.0: 6759 Number of HSP's gapped: 242414 Number of HSP's successfully gapped: 12404 Length of query: 413 Length of database: 3,846,993,858 Length adjustment: 140 Effective length of query: 273 Effective length of database: 2,268,465,438 Effective search space: 619291064574 Effective search space used: 619291064574 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 82 (36.2 bits)