BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MMAR_3690
         (1512 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,275,203 sequences; 3,846,993,858 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|B2HM86|B2HM86_MYCMM Tax_Id=216594 (mbtF)SubName: Full=Non-rib...  2806   0.0  
tr|A0PTU7|A0PTU7_MYCUA Tax_Id=362242 (mbtF)SubName: Full=Non-rib...  2786   0.0  
tr|Q5Z1S9|Q5Z1S9_NOCFA Tax_Id=37329 (nbtE)SubName: Full=Non-ribo...  1783   0.0  
tr|B1MPF3|B1MPF3_MYCA9 Tax_Id=561007 SubName: Full=Putative pept...  1665   0.0  
tr|C1B2E6|C1B2E6_RHOOB Tax_Id=632772 SubName: Full=Non-ribosomal...  1190   0.0  
tr|D0L271|D0L271_GORB4 Tax_Id=526226 SubName: Full=Amino acid ad...  1134   0.0  
tr|A1TBS5|A1TBS5_MYCVP Tax_Id=350058 SubName: Full=Amino acid ad...  1040   0.0  
tr|A0QE95|A0QE95_MYCA1 Tax_Id=243243 SubName: Full=Putative sulf...   935   0.0  
tr|A0R0U4|A0R0U4_MYCS2 Tax_Id=246196 SubName: Full=Peptide synth...   915   0.0  
tr|Q7TYQ8|Q7TYQ8_MYCBO Tax_Id=1765 (mbtF)SubName: Full=PEPTIDE S...   895   0.0  
tr|C1AQU2|C1AQU2_MYCBT Tax_Id=561275 (mbtF)SubName: Full=Peptide...   895   0.0  
tr|A1KL69|A1KL69_MYCBP Tax_Id=410289 (mbtF)SubName: Full=Peptide...   895   0.0  
tr|A5WPZ4|A5WPZ4_MYCTF Tax_Id=336982 SubName: Full=Peptide synth...   895   0.0  
tr|C6DNA5|C6DNA5_MYCTK Tax_Id=478434 SubName: Full=Peptide synth...   893   0.0  
tr|Q7D792|Q7D792_MYCTU Tax_Id=1773 SubName: Full=Peptide synthet...   893   0.0  
tr|A4KJC9|A4KJC9_MYCTU Tax_Id=395095 SubName: Full=Peptide synth...   893   0.0  
tr|A2VKA5|A2VKA5_MYCTU Tax_Id=348776 SubName: Full=Peptide synth...   893   0.0  
tr|O05819|O05819_MYCTU Tax_Id=1773 (mbtF)SubName: Full=PEPTIDE S...   892   0.0  
tr|A5U572|A5U572_MYCTA Tax_Id=419947 (mbtF)SubName: Full=Peptide...   892   0.0  
tr|A3Q277|A3Q277_MYCSJ Tax_Id=164757 SubName: Full=Amino acid ad...   887   0.0  
tr|Q1B6B2|Q1B6B2_MYCSS Tax_Id=164756 SubName: Full=Amino acid ad...   885   0.0  
tr|A1UIR4|A1UIR4_MYCSK Tax_Id=189918 SubName: Full=Amino acid ad...   885   0.0  
tr|A4T2D1|A4T2D1_MYCGI Tax_Id=350054 SubName: Full=Amino acid ad...   882   0.0  
tr|C2AVD1|C2AVD1_TSUPA Tax_Id=521096 SubName: Full=Amino acid ad...   839   0.0  
tr|Q73XY7|Q73XY7_MYCPA Tax_Id=1770 (mbtF)SubName: Full=MbtF;[Myc...   830   0.0  
tr|C1AT72|C1AT72_RHOOB Tax_Id=632772 SubName: Full=Putative non-...   791   0.0  
tr|Q6ZZJ4|Q6ZZJ4_ACTTI Tax_Id=1867 (teiC)SubName: Full=Peptide s...   726   0.0  
tr|Q70AZ7|Q70AZ7_ACTTI Tax_Id=1867 (tcp11)SubName: Full=Non-ribo...   726   0.0  
tr|O85020|O85020_MYCSM Tax_Id=1772 (fxbC)SubName: Full=FxbC; Fla...   724   0.0  
tr|A0QNF1|A0QNF1_MYCS2 Tax_Id=246196 SubName: Full=Amino acid ad...   723   0.0  
tr|Q0S3K6|Q0S3K6_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal...   720   0.0  
tr|B1VL66|B1VL66_STRGG Tax_Id=455632 SubName: Full=Putative NRPS...   718   0.0  
tr|C1AZY4|C1AZY4_RHOOB Tax_Id=632772 SubName: Full=Putative non-...   717   0.0  
tr|A4FE38|A4FE38_SACEN Tax_Id=405948 SubName: Full=Putative non-...   696   0.0  
tr|Q7WZ74|Q7WZ74_9ACTO Tax_Id=93944 (dbv17)SubName: Full=Putativ...   694   0.0  
tr|Q0S1Z9|Q0S1Z9_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal...   688   0.0  
tr|Q8KLL5|Q8KLL5_STRTO Tax_Id=55952 SubName: Full=StaC;[Streptom...   680   0.0  
tr|A8LAS3|A8LAS3_FRASN Tax_Id=298653 SubName: Full=Amino acid ad...   674   0.0  
tr|Q93N87|Q93N87_STRLA Tax_Id=1914 SubName: Full=Peptide synthet...   673   0.0  
tr|C9Z1K9|C9Z1K9_STRSW Tax_Id=680198 SubName: Full=Putative NRPS...   671   0.0  
tr|B7T1D2|B7T1D2_9BACT Tax_Id=164851 (teg7)SubName: Full=Teg7;[u...   668   0.0  
tr|O52820|O52820_AMYOR Tax_Id=31958 SubName: Full=PCZA363.4;[Amy...   667   0.0  
tr|Q939Z0|Q939Z0_9PSEU Tax_Id=208443 (bpsB)SubName: Full=Peptide...   659   0.0  
tr|C1BBK7|C1BBK7_RHOOB Tax_Id=632772 SubName: Full=Non-ribosomal...   640   0.0  
tr|B7T1C1|B7T1C1_9BACT Tax_Id=164851 (veg8)SubName: Full=Veg8;[u...   640   0.0  
tr|O87314|O87314_MYCSM Tax_Id=1772 (fxbC)SubName: Full=FxbC;[Myc...   630   e-178
tr|Q45R83|Q45R83_STRFR Tax_Id=1906 (lptC)SubName: Full=Peptide s...   621   e-175
tr|C0ZRD6|C0ZRD6_RHOE4 Tax_Id=234621 SubName: Full=Putative non-...   620   e-175
tr|B1VQH8|B1VQH8_STRGG Tax_Id=455632 SubName: Full=Putative NRPS...   605   e-170
tr|D1ACW7|D1ACW7_THECU Tax_Id=471852 SubName: Full=Amino acid ad...   600   e-169

>tr|B2HM86|B2HM86_MYCMM Tax_Id=216594 (mbtF)SubName:
            Full=Non-ribosomal peptide synthetase MbtF;[Mycobacterium
            marinum]
          Length = 1512

 Score = 2806 bits (7275), Expect = 0.0
 Identities = 1433/1512 (94%), Positives = 1434/1512 (94%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            +TAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML
Sbjct: 1    MTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
            DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL
Sbjct: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIV 180
            RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAV                  YIV
Sbjct: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVYRAGGAADALPAARPYRDYIV 180

Query: 181  WLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRH 240
            WLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRH
Sbjct: 181  WLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRH 240

Query: 241  GLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSG 300
            GLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSG
Sbjct: 241  GLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSG 300

Query: 301  TEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTP 360
            TEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTP
Sbjct: 301  TEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTP 360

Query: 361  DGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQLP 420
            DGAQFLPVEMESLTHYPLTVVSHLR               PYLPAAEIGERMLTVLRQLP
Sbjct: 361  DGAQFLPVEMESLTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERMLTVLRQLP 420

Query: 421  DIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVR 480
            DIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQ            GVR
Sbjct: 421  DIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQATPDAVALTAAAGVR 480

Query: 481  HTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLP 540
            HTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS             YLPVDVTLP
Sbjct: 481  HTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSIVAILGVLAAGGAYLPVDVTLP 540

Query: 541  SARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQ 600
            SARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQ
Sbjct: 541  SARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQ 600

Query: 601  SAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS 660
            SAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVY              HAWSLSFDAS
Sbjct: 601  SAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYRAARARLGRPLRIAHAWSLSFDAS 660

Query: 661  WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLS 720
            WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLS
Sbjct: 661  WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLS 720

Query: 721  VLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFG 780
            VLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVE      KDYRKPTIGTANAGTFG
Sbjct: 721  VLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEAVVAAVKDYRKPTIGTANAGTFG 780

Query: 781  YVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRR 840
            YVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRR
Sbjct: 781  YVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRR 840

Query: 841  LSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVW 900
            LSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVW
Sbjct: 841  LSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVW 900

Query: 901  QDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSG 960
            QDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSG
Sbjct: 901  QDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSG 960

Query: 961  GTAVSASTDTERVLCELFEEQLNAVPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRM 1020
            GTAVSASTDTERVLCELFEEQLNAVPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRM
Sbjct: 961  GTAVSASTDTERVLCELFEEQLNAVPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRM 1020

Query: 1021 VLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRRFTHTVLLRLPS 1080
            VLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRRFTHTVLLRLPS
Sbjct: 1021 VLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRRFTHTVLLRLPS 1080

Query: 1081 GIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDE 1140
            GIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDE
Sbjct: 1081 GIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDE 1140

Query: 1141 LASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIML 1200
            LASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIML
Sbjct: 1141 LASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIML 1200

Query: 1201 GDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALG 1260
            GDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALG
Sbjct: 1201 GDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALG 1260

Query: 1261 LRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQ 1320
            LRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQ
Sbjct: 1261 LRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQ 1320

Query: 1321 DPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQD 1380
            DPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQD
Sbjct: 1321 DPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQD 1380

Query: 1381 LVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLL 1440
            LVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLL
Sbjct: 1381 LVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLL 1440

Query: 1441 TGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLW 1500
            TGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLW
Sbjct: 1441 TGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLW 1500

Query: 1501 QRGIAALAAGLD 1512
            QRGIAALAAGLD
Sbjct: 1501 QRGIAALAAGLD 1512


>tr|A0PTU7|A0PTU7_MYCUA Tax_Id=362242 (mbtF)SubName:
            Full=Non-ribosomal peptide synthetase MbtF;[Mycobacterium
            ulcerans]
          Length = 1512

 Score = 2786 bits (7222), Expect = 0.0
 Identities = 1422/1512 (94%), Positives = 1427/1512 (94%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            +TAAAPQIEDVLAL+PLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML
Sbjct: 1    MTAAAPQIEDVLALTPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
            DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL
Sbjct: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIV 180
            RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAV                  YIV
Sbjct: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVYRAGGAADALPAARPYRDYIV 180

Query: 181  WLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRH 240
            WLA QDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRH
Sbjct: 181  WLANQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRH 240

Query: 241  GLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSG 300
            GLTLNT VLFAWAVVLSRLTDRRDVVFGTVVSGRPDQL GVETMVGLFINAVPVVHYVSG
Sbjct: 241  GLTLNTTVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLLGVETMVGLFINAVPVVHYVSG 300

Query: 301  TEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTP 360
            TEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTP
Sbjct: 301  TEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTP 360

Query: 361  DGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQLP 420
            DGAQFLPVEMESLTHYPLTVVSHLR               PYLPAAEIGERMLTVLRQLP
Sbjct: 361  DGAQFLPVEMESLTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERMLTVLRQLP 420

Query: 421  DIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVR 480
            DIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQ            GVR
Sbjct: 421  DIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQTTPDAVALAAAGGVR 480

Query: 481  HTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLP 540
            HTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS             YLPVDVTLP
Sbjct: 481  HTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSIVAILGVLAAGGAYLPVDVTLP 540

Query: 541  SARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQ 600
            SARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAV+SISRRSAAAPTVDRRPEQ
Sbjct: 541  SARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVDSISRRSAAAPTVDRRPEQ 600

Query: 601  SAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS 660
            SAYVIFTSGSTGEPKGV GTNAAVLSYFADHAERVY              HAWSLSFDAS
Sbjct: 601  SAYVIFTSGSTGEPKGVAGTNAAVLSYFADHAERVYRAARARLGRPLRIAHAWSLSFDAS 660

Query: 661  WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLS 720
            WQPMVGLLDGHEIHLFDA+EMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLS
Sbjct: 661  WQPMVGLLDGHEIHLFDADEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLS 720

Query: 721  VLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFG 780
            VLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVE      KDYRKPTIGTANAGTFG
Sbjct: 721  VLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEAVVAAVKDYRKPTIGTANAGTFG 780

Query: 781  YVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRR 840
            YVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRR
Sbjct: 781  YVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRR 840

Query: 841  LSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVW 900
            LSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVW
Sbjct: 841  LSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVW 900

Query: 901  QDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSG 960
            QDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSG
Sbjct: 901  QDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSG 960

Query: 961  GTAVSASTDTERVLCELFEEQLNAVPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRM 1020
            GTAVSASTDTERVLCELFEEQLNAVPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRM
Sbjct: 961  GTAVSASTDTERVLCELFEEQLNAVPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRM 1020

Query: 1021 VLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRRFTHTVLLRLPS 1080
            VLTATTIRQLGAAIDAAVDSQDAPADADYGAV PLPMVSWLYEYGNYRRFTHTVLLRLPS
Sbjct: 1021 VLTATTIRQLGAAIDAAVDSQDAPADADYGAVLPLPMVSWLYEYGNYRRFTHTVLLRLPS 1080

Query: 1081 GIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDE 1140
            GIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRI LPEGSDDE
Sbjct: 1081 GIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRIRLPEGSDDE 1140

Query: 1141 LASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIML 1200
            LASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPAN+LLLTAHHLAVDVVSWHIML
Sbjct: 1141 LASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANMLLLTAHHLAVDVVSWHIML 1200

Query: 1201 GDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALG 1260
            GDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDP LG
Sbjct: 1201 GDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPELG 1260

Query: 1261 LRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQ 1320
            LRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQ
Sbjct: 1261 LRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQ 1320

Query: 1321 DPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQD 1380
            DPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQD
Sbjct: 1321 DPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQD 1380

Query: 1381 LVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLL 1440
            LVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLL
Sbjct: 1381 LVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLL 1440

Query: 1441 TGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLW 1500
            TGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLW
Sbjct: 1441 TGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLW 1500

Query: 1501 QRGIAALAAGLD 1512
            QRGIAALAAGLD
Sbjct: 1501 QRGIAALAAGLD 1512


>tr|Q5Z1S9|Q5Z1S9_NOCFA Tax_Id=37329 (nbtE)SubName: Full=Non-ribosomal
            peptide synthetase;[Nocardia farcinica]
          Length = 1522

 Score = 1783 bits (4617), Expect = 0.0
 Identities = 928/1521 (61%), Positives = 1084/1521 (71%), Gaps = 16/1521 (1%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            +T A PQIEDVLALSPLQEGLF+L ++  D +DLY+MQFVVDIDGP+D+ LLRRSAQAML
Sbjct: 1    MTGATPQIEDVLALSPLQEGLFSLARVGGDDLDLYTMQFVVDIDGPLDVALLRRSAQAML 60

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
            DRHPNLRAAFWDRDVPKPVQIVP HA LPW+ER A PAEF +IA SERRRPFDLSRGPAL
Sbjct: 61   DRHPNLRAAFWDRDVPKPVQIVPSHAELPWTERQAQPAEFATIAESERRRPFDLSRGPAL 120

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIV 180
            R+V+L VP + +RRMI TAHHIL+DGW++AVFFTELLAV                  YI 
Sbjct: 121  RIVLLEVPEQARRRMILTAHHILMDGWAVAVFFTELLAVYRSGGDLSVLPAARPYRDYIA 180

Query: 181  WLAKQDRSAALAGWMDYLRGVSEPLMVAY-EATAGQSKPGKTELLLPAADTARLRQWAGR 239
            WLA QD +AA A W++YL G++  LM+A   A    + P  T + L AA+  RL+QWA  
Sbjct: 181  WLAGQDTAAATARWVEYLSGLNGALMLADGSAQVRGAVPETTAVRLSAAENERLQQWARA 240

Query: 240  HGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVS 299
            +GLTL TAV FAW VVL RLTDRRDVVFGT +SGRPDQLPGVE MVGLFIN VPVVH++ 
Sbjct: 241  NGLTLATAVQFAWTVVLGRLTDRRDVVFGTTISGRPDQLPGVEGMVGLFINTVPVVHHLD 300

Query: 300  GTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATT 359
                VV QC ++QR S+AMRD+ YLSLS +QR  G G LFD+LFVFENAPI DAI+  T 
Sbjct: 301  RDTTVVEQCVRMQRDSAAMRDIGYLSLSAVQRAAGHGTLFDTLFVFENAPIGDAIQTVTA 360

Query: 360  PDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQL 419
            PDGA+F PVEMESL HYPLTVV+HL                PY   A+I ER+L VLR L
Sbjct: 361  PDGARFRPVEMESLAHYPLTVVAHLDGPELLVLVEAIPEALPYFSPADIAERLLAVLRAL 420

Query: 420  PDIGDGTPDDLDIRTAAELKAHGLLAARS--------APTFDTTVWEMFERQVQXXXXXX 471
            PD G  TPD LDI T AE    G  AA S        A     T+WE+FERQV+      
Sbjct: 421  PDSGSLTPDALDILTPAERAEFGGTAATSSADEAADLADVAGLTIWELFERQVERTPDAL 480

Query: 472  XXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXX 531
                  G R TY ELHA A RLAGELAEHGVGPE VVAL LPRS +S             
Sbjct: 481  ALTTGAGDRVTYRELHAAAARLAGELAEHGVGPERVVALTLPRSAQSLVAILAVLAAGGA 540

Query: 532  YLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAA 591
            Y+PVD+ LP  R++SI+RQA+P LA+T A  +   G  VPTL LDDPA  + I+ R   A
Sbjct: 541  YVPVDIALPQTRIDSILRQAAPVLALTVAATAASAGD-VPTLVLDDPAVRQRIAAREPVA 599

Query: 592  PTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXH 651
            P V R PE  AY+IFTSGSTGEPKGV  TNAAV +YFADH  R Y              H
Sbjct: 600  PVVARHPEHCAYIIFTSGSTGEPKGVADTNAAVAAYFADHRARCYRPATARLGRPLRIAH 659

Query: 652  AWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSA 711
            AWSLSFDASWQPMVGLLDG  +HLFDAEEMRDA R+V G+A   +DMIDTTPSM  QL A
Sbjct: 660  AWSLSFDASWQPMVGLLDGQALHLFDAEEMRDAGRIVAGMAEFGVDMIDTTPSMLAQLDA 719

Query: 712  AGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTI 771
            AGLL+  L VLALGGEAI+T LW++LR L   AVYNCYGPTE TVE        Y  PTI
Sbjct: 720  AGLLERRLPVLALGGEAIDTALWNRLRALPDTAVYNCYGPTETTVEAVVAPVGRYETPTI 779

Query: 772  GTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRM 831
            GT NAG  GYV DS LR VP G VGELYL+G QLARGYVG+PG+TA RFVADPLRPG RM
Sbjct: 780  GTPNAGMAGYVLDSMLRPVPRGAVGELYLAGPQLARGYVGKPGVTADRFVADPLRPGARM 839

Query: 832  YRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDR 891
            YRTGDLVRRL HGG+AY+GRAD QVKIRGYR+E+GEIE ALR  PGV  AAV+V+R+   
Sbjct: 840  YRTGDLVRRLPHGGFAYLGRADDQVKIRGYRIEIGEIETALRRLPGVRTAAVTVVRRAGG 899

Query: 892  TSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLA 951
             SLVGFVV       +  +LRA L +RLP+YMVPARIV L +LPVNANGKLDGH L  LA
Sbjct: 900  ASLVGFVVGDTASTGEAPRLRATLAQRLPAYMVPARIVVLDQLPVNANGKLDGHRLTALA 959

Query: 952  EDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLFGMDSIVAISLVHKAR 1010
            E AL    G      +TDTER LCE+F E  +   P IDDD F  G+DSIVAISLV+KAR
Sbjct: 960  EQALAG-GGADRAEPTTDTERALCEVFAELFDGTAPGIDDDFFALGVDSIVAISLVNKAR 1018

Query: 1011 RQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRRF 1070
            R+G+ + PRMVL+  T+R+L AA+DAAVD       A+YG V PLP+VSW+YEYGN+RRF
Sbjct: 1019 RRGITLSPRMVLSTPTVRELAAAVDAAVDIAGPAEAAEYGEVPPLPVVSWMYEYGNHRRF 1078

Query: 1071 THTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTR 1130
            T + LLR+P+ +  +++  +LQ LLDGHDTLR++  +T +GPRLVTREP  VRA D+LTR
Sbjct: 1079 TQSALLRVPTAMPSATLVTVLQALLDGHDTLRAVEADTADGPRLVTREPGVVRAADLLTR 1138

Query: 1131 ITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLA 1190
            + LP  ++ EL +A+   AR   D IDP  G+MVRA+WF G    A   +ILLL  HHLA
Sbjct: 1139 VELPGATEAELDAAIRTHARAANDAIDPRTGSMVRAVWFTG----APDGDILLLAVHHLA 1194

Query: 1191 VDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAA 1250
            VDVVSWHIML  LA AW+++++G  PK LPEFTSYRRW +LMW RA+ PQV  QRDYWA+
Sbjct: 1195 VDVVSWHIMLAGLAEAWQAVESGAVPKTLPEFTSYRRWSQLMWQRAAEPQVLAQRDYWAS 1254

Query: 1251 LVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMA 1310
             VR+PDPALG R+P P  DTWS L++T A  PV VTE+VL  + RD+GVRE LLAA  + 
Sbjct: 1255 QVRDPDPALGRRHPHPATDTWSGLRVTPALTPVAVTEQVLAGLGRDEGVREFLLAALTLT 1314

Query: 1311 VASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQ 1370
            +ASWR  R  DP AG L+ALEGHGRADA L  DT+NT+GWFT  FPVRLG GAAAVD+ +
Sbjct: 1315 LASWRAERGDDPGAGALIALEGHGRADAALGADTSNTLGWFTTVFPVRLGTGAAAVDLAR 1374

Query: 1371 AERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLG 1430
             E DP A + L+ SV +HL AIP  GLDYGLLRYV   AEL    +PQ++F+YLGR+DL 
Sbjct: 1375 VEADPGAGRALLDSVTAHLAAIPEQGLDYGLLRYVARAAELRTGAEPQVEFNYLGRVDLS 1434

Query: 1431 GVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFER 1490
            G    PWSLLTGP  +ALP+DPEPDLPLR+AL++   VG T EG QL  NWRWS  +F  
Sbjct: 1435 GSVGAPWSLLTGPRNEALPLDPEPDLPLRYALDVIAAVGSTPEGPQLSTNWRWSADLFTA 1494

Query: 1491 SDIDHLTGLWQRGIAALAAGL 1511
            ++ D L  LWQR IAALAA L
Sbjct: 1495 AEADRLAELWQRSIAALAAAL 1515


>tr|B1MPF3|B1MPF3_MYCA9 Tax_Id=561007 SubName: Full=Putative peptide
            synthetase MbtF;[Mycobacterium abscessus]
          Length = 1509

 Score = 1665 bits (4311), Expect = 0.0
 Identities = 866/1513 (57%), Positives = 1054/1513 (69%), Gaps = 10/1513 (0%)

Query: 2    TAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLD 61
            T   PQIEDVLALSPLQEG FAL QLA++ VDLYSMQFV DIDG +D++LL RSAQA+L 
Sbjct: 4    TEQQPQIEDVLALSPLQEGFFALSQLADESVDLYSMQFVADIDGGLDVDLLHRSAQALLT 63

Query: 62   RHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALR 121
            RHPNLRAAFWDR +PKPVQIVP HA +PW ER A P EFD IA  ER RPF+L +GPA+R
Sbjct: 64   RHPNLRAAFWDRGLPKPVQIVPTHADIPWEEREAQPTEFDEIALRERLRPFNLGKGPAIR 123

Query: 122  VVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVW 181
            +V+L+VPGE++ RMI T+HHIL+DGW++A+FF+ELLAV                  YI W
Sbjct: 124  LVLLTVPGESRHRMIVTSHHILMDGWAIAIFFSELLAVYQAGGSLAGLPAVRPYRDYIAW 183

Query: 182  LAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSK-PGKTELLLPAADTARLRQWAGRH 240
            L  QD + A A W  YL  VS PLM+A  A A     P K++ LL   +TARLRQWA  +
Sbjct: 184  LNAQDTTEATARWTRYLGTVSGPLMLADGAVAAHDNVPEKSQFLLAPEETARLRQWAAAN 243

Query: 241  GLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSG 300
            GLTLNT   FAWA+VL RLTDR DVVFGT+VSGRP +LP VE MVGLFIN+VP+VH++  
Sbjct: 244  GLTLNTVTAFAWALVLGRLTDRTDVVFGTIVSGRPKELPDVERMVGLFINSVPMVHHIDY 303

Query: 301  TEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTP 360
            + +VV QC Q+QR+++AMRD+ YLSLS +QR  G   LFD+LFVFENAPI D ++     
Sbjct: 304  SASVVEQCVQLQREAAAMRDIGYLSLSTLQRAEGSAALFDTLFVFENAPIGDVVQEVEMA 363

Query: 361  DGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQLP 420
            DGA+F PVEMESL HYPLTVVSH+                P++  A +GER+++VLRQLP
Sbjct: 364  DGARFRPVEMESLAHYPLTVVSHMHGDSLLVLIEAIPQALPHVSGASVGERLVSVLRQLP 423

Query: 421  DIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVR 480
            DIG GTPD L++ TA E +A  ++ A +A     +VW++FER+ Q            G R
Sbjct: 424  DIGGGTPDALELLTARE-RAEIVVTASAADPSVVSVWDLFEREAQAHPESLALVADAGTR 482

Query: 481  HTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLP 540
            +TYA+L     RL  EL E GV PET VAL LPRS  S             Y+PVD+ LP
Sbjct: 483  YTYAQLRGAVSRLCAELIESGVTPETTVALALPRSADSIIAILAVLAAGAAYVPVDIGLP 542

Query: 541  SARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQ 600
            +ARVESI+RQ++P L IT   +  + G     L LDDP     IS RS +   V    +Q
Sbjct: 543  AARVESILRQSNPTLVITVDRHRDIAGRGYQVLILDDPETAARISGRSESGHAVVVHRDQ 602

Query: 601  SAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS 660
            SAY+IFTSGSTGEPKGVVGT+AA++SYFADH +RVY              HAWSLSFDAS
Sbjct: 603  SAYLIFTSGSTGEPKGVVGTHAALMSYFADHRDRVYRPATARLGRKLRIAHAWSLSFDAS 662

Query: 661  WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLS 720
            WQPM+GLLDGH +HLFDAE MRDA  LV G+A   +DMIDTTPSM  QLSAAGLLDH L+
Sbjct: 663  WQPMIGLLDGHAVHLFDAEAMRDASLLVRGMAERGVDMIDTTPSMLAQLSAAGLLDHELA 722

Query: 721  VLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFG 780
            VLALGGEAI T LWD+LR LS  AVYNCYGPTE TVE      K+Y  PTIGT N G  G
Sbjct: 723  VLALGGEAIETALWDRLRSLSDTAVYNCYGPTETTVEAVVAAVKEYPAPTIGTPNQGMVG 782

Query: 781  YVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRR 840
            YV DS LR VPDG VGELYL+GAQLARGY G+P +TAA FVADP R GQRMYRTGDLVRR
Sbjct: 783  YVLDSRLRPVPDGAVGELYLAGAQLARGYAGKPAVTAAAFVADPRRAGQRMYRTGDLVRR 842

Query: 841  LSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVW 900
            L HGG+AY+GRAD+QVKIRGYRVEVGEIE+ALR QP +  AAV+V+R+    SLVGFVV 
Sbjct: 843  LPHGGFAYLGRADSQVKIRGYRVEVGEIESALRLQPDIQTAAVTVVRRAGGASLVGFVVC 902

Query: 901  QDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSG 960
            + +   D  +    L +RLPSYM+P+R+V LP+LPV  NGKLDG AL+RLA +AL+  + 
Sbjct: 903  EKDTF-DSARTMMRLADRLPSYMMPSRLVPLPQLPVTVNGKLDGGALERLAREALSGGAV 961

Query: 961  GTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPR 1019
            G     +T TE VLCE   E  +   P ID+D F  G+DSIVAISLV+KAR++ L + PR
Sbjct: 962  GEQAQPATATECVLCECCAELFDGTAPGIDEDFFSLGVDSIVAISLVNKARKRDLVITPR 1021

Query: 1020 MVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRRFTHTVLLRLP 1079
            MVL A TIRQL A +D          +ADYG V PLP+VSW+YE   YRR + +VL+RLP
Sbjct: 1022 MVLAAPTIRQLAALVDTRGHVDSLAGEADYGEVPPLPVVSWMYESEIYRRLSLSVLVRLP 1081

Query: 1080 SGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDD 1139
            +GIDR  IE MLQLLLDG   LRS L +TP+G R+VTREP  VR E VL+R+ LP G  +
Sbjct: 1082 AGIDRPGIERMLQLLLDGFTMLRSTLVDTPDGARVVTREPGVVRGESVLSRVELPTG--E 1139

Query: 1140 ELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIM 1199
               +A+ +AAR   D +DP +GAM+RA+W        D  ++LLLT HHLA+DVVSWHI+
Sbjct: 1140 SAHAAITNAARQAFDSLDPRSGAMMRAVWLAS----RDSGDVLLLTVHHLAMDVVSWHIV 1195

Query: 1200 LGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPAL 1259
            LG LA AW ++++GT PK   EFTSYR+W +LM  RAS+  V  QRDYWA  V   DP L
Sbjct: 1196 LGYLADAWIAVRSGTAPKAPMEFTSYRQWSQLMHQRASSHDVLRQRDYWAEQVSGADPEL 1255

Query: 1260 GLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRA 1319
            G R+ DP+RDTW TLQ T    PV VT R+L ++ + +GV   LL+A A+ VASWR++R 
Sbjct: 1256 GSRHADPSRDTWGTLQTTAVPTPVAVTTRLLASLNKPEGVYSFLLSALAVTVASWRKLRG 1315

Query: 1320 QDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQ 1379
            QD  AG LV+LEGHGRAD  LDTDT+ TVGWFT  +PVR+ AG AA+D+++ E D  AA+
Sbjct: 1316 QDSTAGTLVSLEGHGRADGELDTDTSGTVGWFTTVYPVRVAAGEAAIDVDRMENDVNAAR 1375

Query: 1380 DLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSL 1439
             L+  V  H++ IP  GLDYGLLRYV G  EL  A DPQIQF+Y+GR+D+ G+ DQPWSL
Sbjct: 1376 QLLAGVARHIDEIPYQGLDYGLLRYVRGCEELSSARDPQIQFNYVGRMDISGIDDQPWSL 1435

Query: 1440 LTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGL 1499
            +T     A+P D EPDLPLRFA+N+   V  T EG QL+ NW+ S A+F  +D   L  L
Sbjct: 1436 ITDARSLAVPPDSEPDLPLRFAINIGSAVMTTPEGPQLLTNWQLSSALFTPADASRLAQL 1495

Query: 1500 WQRGIAALAAGLD 1512
            WQR +AALA  LD
Sbjct: 1496 WQRSVAALAGALD 1508


>tr|C1B2E6|C1B2E6_RHOOB Tax_Id=632772 SubName: Full=Non-ribosomal
            peptide synthetase;[Rhodococcus opacus]
          Length = 1519

 Score = 1190 bits (3078), Expect = 0.0
 Identities = 705/1553 (45%), Positives = 888/1553 (57%), Gaps = 92/1553 (5%)

Query: 5    APQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHP 64
            AP+IEDVL LSPLQEGLF L +   DGVD Y++QFV DIDGPVD+ LLRRS  A+L RHP
Sbjct: 8    APEIEDVLVLSPLQEGLFTLARTITDGVDPYTIQFVADIDGPVDVPLLRRSIDAVLGRHP 67

Query: 65   NLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVV 124
            NLR +FWDRD+P PVQIVP    +PW E  A   E  ++A +ERRRPFDL+ GPALR V 
Sbjct: 68   NLRVSFWDRDLPHPVQIVPARVTVPWREVDAAAGELAALADAERRRPFDLANGPALRFV- 126

Query: 125  LSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAK 184
            L+       R+I TAHHI++DGWS+ +F  EL+                    YI WLA 
Sbjct: 127  LARRAPASFRLICTAHHIVMDGWSVPIFVQELVGAYLADGSLDLLLAPRLYRDYIAWLAA 186

Query: 185  QDRSAALAGWMDYLRGVSEPLMVAY----EATAG-QSKPGKTELLLPAADTARLRQWAGR 239
            QD+ AAL  W D+L  +  P M+A       +AG  + PGK EL L A DT  L QW   
Sbjct: 187  QDKVAALTAWRDHLADIDGPTMLAEGRFRRTSAGVDTLPGKAELTLGARDTDALLQWTRA 246

Query: 240  HGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVS 299
            HGLT+NTA  FAWA++L RLTDR  VVFG   +GRPD L GVETM+GLFIN +PV   + 
Sbjct: 247  HGLTVNTATQFAWALLLGRLTDRTSVVFGATTAGRPDSLAGVETMIGLFINTLPVHVRLD 306

Query: 300  GTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATT 359
                V+ QCT +Q++ + +R   Y+ LSE+QR  G G LFDSL VF+NAP      P T 
Sbjct: 307  DATTVLEQCTALQQEFARLRTHGYVGLSEVQRLAGTGDLFDSLMVFQNAPRGSVADPVTA 366

Query: 360  PDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQL 419
            PDG  F PVEM+SLTHYPLT+V +L                P+L A E+GER+L VLRQL
Sbjct: 367  PDGVTFTPVEMDSLTHYPLTLVPYLDGGTLGLVVEHRPDLLPHLGAHEVGERLLHVLRQL 426

Query: 420  PDIGDGTPDDLDIRTAAELK---------------------AHGLLAARSAPTFDTTVWE 458
            P  GD  P  +DI    E +                      HGLLA  +A T D     
Sbjct: 427  PRAGDARPGVIDILVPGERERILAAAVTPEILCGELPPAATVHGLLAHHAAVTPDAAAIT 486

Query: 459  MFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS 518
              E                 +  T+ ++ A A RLA EL + G+ PE  VA+VLPRS   
Sbjct: 487  TSE-----------------ITLTHRDVDAAANRLARELLDRGIRPEEAVAVVLPRSPEF 529

Query: 519  XXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDP 578
                          +P+ V  P+AR +SI+ Q    +A+T  +++ + G      A+D P
Sbjct: 530  LISMFAVAKAGGTAVPLAVDGPAARRDSILTQTGARIALTTPEFA-IAGLD----AVDVP 584

Query: 579  AAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXX 638
              +       A +P VD  P QS YVIFTSGSTGEPKGVV T+  ++   ADH  RVY  
Sbjct: 585  TVLAGAG--PAPSPGVDVDPAQSLYVIFTSGSTGEPKGVVATHRGIVRLLADHRRRVYRP 642

Query: 639  XXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDM 698
                        HAWSL+FDASWQP++ LLDGH + LFD++ MRD D LV GI    +DM
Sbjct: 643  AAQRLGRPLTVGHAWSLTFDASWQPLLALLDGHAVALFDSDAMRDPDLLVRGIVARGVDM 702

Query: 699  IDTTPSMFVQLSAAGLLDHN-------LSVLALGGEAINTGLWDQLRGLSQMAVYNCYGP 751
            ++T+P+MF QL+ AGLL  +       L+VL LGGEA+    W + R L    V+N YGP
Sbjct: 703  LETSPAMFTQLAPAGLLFEDGGETRCRLAVLGLGGEAVGEAAWARCRALPGTDVFNFYGP 762

Query: 752  TEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVG 811
            TE TV+       D   P++G   AG   YV DSALR+VPDGV GELYLSG Q+ RGY+ 
Sbjct: 763  TETTVDALVAGFADTPAPSVGRPLAGMGAYVLDSALRLVPDGVAGELYLSGDQVTRGYLD 822

Query: 812  RPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAA 871
            RPG T+ RFVA P   G+R+YRTGDLVRR   G + Y+GR D Q++IRG+RVE+ EIEAA
Sbjct: 823  RPGSTSERFVAHPFALGERLYRTGDLVRRTPTGTFDYLGRGDDQIQIRGHRVELAEIEAA 882

Query: 872  LRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTL 931
            L+  P V  AAV    +     L  FVV   ++  D   LR  L + LP YM+P+R   +
Sbjct: 883  LQALPEVTSAAVLTAERPTGPGLTAFVVSSGDI--DPSALRTALADTLPPYMIPSRFTGV 940

Query: 932  PRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDD 990
              LP   NGKLD  AL  LA +A     G     A T TE +L  L  E +         
Sbjct: 941  TELPRTPNGKLDARAL--LAVEARREDDGD--AEAETPTEALLLRLLAELVGTDSIGATT 996

Query: 991  DLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYG 1050
            D F  G+DSI AIS V+K R  GL + PR+V T  T+R L AA D A  +      A+ G
Sbjct: 997  DFFDLGVDSIAAISFVNKVRAHGLAITPRLVATHPTVRDLAAAADRAAATTAVRGPAEVG 1056

Query: 1051 AVRPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPE 1110
             V PLP+VSWL+E   +RRFT T L+RLP+ +    +   LQ ++D H  LR+ILT T  
Sbjct: 1057 EVPPLPVVSWLFECDGFRRFTQTQLIRLPADVTERRLAGTLQTVIDAHAVLRAILTRTGR 1116

Query: 1111 GPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFR 1170
            G R+VTRE   V A  +L  + +     D LA+     AR   D+IDP  G  ++A+ FR
Sbjct: 1117 GYRVVTREAGTVPAASLLQAVEVTGALGDHLAA----EARAAIDRIDPEHGVPLQAVLFR 1172

Query: 1171 GTEHRADP--ANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRW 1228
                 A    A +LLLT HHLAVD VSW ++L DLAAAW     GT   + PE TSYRR+
Sbjct: 1173 PQPGVAQQQRAPVLLLTIHHLAVDAVSWAVLLADLAAAWE----GT--ALPPEATSYRRF 1226

Query: 1229 CELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTER 1288
             ELM  RA  P+V  QRD+W      PDP LG R  DP  D  S+L +T       VT  
Sbjct: 1227 SELMAERAETPEVVAQRDFWVRQCAGPDPVLGSRRLDPAVDRASSLAVTTTVTSPQVTAS 1286

Query: 1289 VLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD---TDTT 1345
            V   V R  GVRE+LLAA A  VA WRR+R  DPAAG LVALEGHGRAD ++    TDTT
Sbjct: 1287 V---VARAAGVREILLAALAATVAQWRRLRGDDPAAGTLVALEGHGRADHLVSDFGTDTT 1343

Query: 1346 NTVGWFTNAFPVRLGAGAAAVDI------EQAERDPVAAQDLVHSVVSHLEAIPNDGLDY 1399
             TVGWFT  FPVRLGAGA           ++  RD      ++  + + + A+PN G D+
Sbjct: 1344 RTVGWFTTVFPVRLGAGAGWAHTLDPDVPDRGLRDRGVLDRILADISADVGAVPNAGTDF 1403

Query: 1400 GLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDA-LPIDPEPDLPL 1458
            GLLR+     +L  AVDPQI+F+YLGR D G      WS +T   L A LP+ PEPDLPL
Sbjct: 1404 GLLRWTAEDPQL--AVDPQIEFNYLGRFDFGPETVGDWSPITDRDLHARLPLAPEPDLPL 1461

Query: 1459 RFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGL 1511
            R+ L +   VG  + G +++ +WRWS  VF + +ID +T LW   +AA A  L
Sbjct: 1462 RYELEVIAAVGSNSRGPEIVTSWRWSRDVFTQEEIDRVTCLWNDALAAFAEAL 1514


>tr|D0L271|D0L271_GORB4 Tax_Id=526226 SubName: Full=Amino acid
            adenylation domain protein;[Gordonia bronchialis]
          Length = 1529

 Score = 1134 bits (2932), Expect = 0.0
 Identities = 683/1549 (44%), Positives = 885/1549 (57%), Gaps = 71/1549 (4%)

Query: 8    IEDVLALSPLQEGLFALHQLA--EDGV-------DLYSMQFVVDIDGPVDLELLRRSAQA 58
            I+DV+ALSPLQEGLF+L +LA   DG        D+Y++  +VDI GP+D   LR + + 
Sbjct: 4    IDDVIALSPLQEGLFSLARLATERDGPGGDDAEGDVYTIPLIVDISGPLDRAALRTACEN 63

Query: 59   MLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGP 118
            +L RHPNLRA FWD+DVPKPVQIVP   ++PW++   +    D+    E RR FDL  GP
Sbjct: 64   ILIRHPNLRAVFWDKDVPKPVQIVPTEVSMPWADHELSEEAADAFTEREVRRVFDLRDGP 123

Query: 119  ALRVVVLSVPG--ETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXX 176
            +LR  ++ +      + R+I T HHIL+DGWS+ VFF ELL +                 
Sbjct: 124  SLRFTLIRITDVPAPRHRLIVTVHHILMDGWSVGVFFAELLQMYRAGGSADALGPVRPYR 183

Query: 177  XYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSK-----PGKTELLLPAADTA 231
             YI WL  QD++A +A W   L  +S PLM A  A+ G        P      + A  TA
Sbjct: 184  DYIAWLNAQDQAAMIARWSAVLGQLSGPLMFAEVASTGLDATDTRTPVAWHYTVDAERTA 243

Query: 232  RLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINA 291
            RL  W+   G+TLNTAV FAW +VLSRL DRRDVV+GTVV+GRP Q+   + M+GLF+N 
Sbjct: 244  RLIDWSRAQGITLNTAVQFAWTLVLSRLMDRRDVVYGTVVTGRPHQVTDADRMIGLFLNT 303

Query: 292  VPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPID 351
            +PV   +     V A+C ++QR+S+ +RD+ YLSLS +QR  G   LFD++FVF+NAP+D
Sbjct: 304  IPVAFTLDPDADVAAECRRLQRESAELRDIGYLSLSAVQRAAGHSALFDTMFVFQNAPMD 363

Query: 352  DAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGER 411
             A    TTPDG  F P   ++LTHYPLTVV++L                P + +  +   
Sbjct: 364  QA-GDTTTPDGVTFAPAMAQNLTHYPLTVVAYLHSDELLVAVEAIESVLP-VDSDALAAL 421

Query: 412  MLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTT----VWEMFERQVQXX 467
            +L  L +LP  G+ +  D+DI      +A  L+A  + P    T    + E+F RQV   
Sbjct: 422  LLDTLDRLPVSGERSVGDVDIVGPERRRA--LIAESTTPPTPGTGTEDIVELFVRQVNST 479

Query: 468  XXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXX 527
                        R TY E+   A  LA  L   GVGPE  VA+ LPR   S         
Sbjct: 480  PGAIALTDGH-TRLTYREVLDDALSLADVLRSAGVGPEDFVAICLPRGVDSIVSILASLA 538

Query: 528  XXXXYLPVDVTLPSARVESIVRQASPALAI----TEADYSQLVGTAVPTLALDDPAAVES 583
                Y+PVD+TLP+ R+ SI+ Q  PA  I    T+  +  L   A   + L DP   + 
Sbjct: 539  AGGAYVPVDITLPAERISSILTQVRPAAIIINTSTDPGHVALQPDAATIVDLGDPVIRDR 598

Query: 584  ISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXX 643
                    PT  R+P Q+AY IFTSGSTGEPKGVV ++AA+ SYFADH ERVY       
Sbjct: 599  ARSPMTGLPT-RRQPAQAAYAIFTSGSTGEPKGVVNSDAALASYFADHRERVYRPARARL 657

Query: 644  XXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTP 703
                   HAWSLSFDASWQPM+GL DGH IHLFD + MRD D LV GI   +IDMIDTTP
Sbjct: 658  GRPLRIAHAWSLSFDASWQPMIGLFDGHTIHLFDDDAMRDTDLLVTGIRDQRIDMIDTTP 717

Query: 704  SMFVQLSAAGLL-----------DHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPT 752
            SMF QL+ AGL+           D  LSVLALGGEAI+  LWD+LR L+ +AV+NCYGPT
Sbjct: 718  SMFRQLAHAGLVDGYTMSTAGTDDAPLSVLALGGEAIDDALWDRLRSLTGVAVHNCYGPT 777

Query: 753  EMTVE--XXXXXXKDYRKP--TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARG 808
            E TVE         D   P  TIG   A   GYV DS LR VPDGV GELYL+G Q+ RG
Sbjct: 778  ETTVEAVVADVTGADASSPTATIGRPTAAMSGYVLDSGLRQVPDGVTGELYLAGPQVTRG 837

Query: 809  YVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGE 867
            Y+GR   TA RFVADP   PG+RMYRTGDLVRR   G   Y+GRAD QVK+RGYRVE+GE
Sbjct: 838  YLGRFSQTAERFVADPFGPPGRRMYRTGDLVRRRPGGALHYLGRADDQVKVRGYRVEIGE 897

Query: 868  IEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPAR 927
            IE ALRG   V DAA  V+R+     LVGFVV   +   D I +R G+ +RLPSYM+PAR
Sbjct: 898  IEKALRGAACVRDAAAVVVRRPVGAVLVGFVVPVADGSADPIAIRTGMADRLPSYMIPAR 957

Query: 928  IVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV-P 986
            ++ +  LPV  NGKLD HAL  LA  AL S S        T+T+R L +   E    V P
Sbjct: 958  LLVVAELPVTVNGKLDSHALTNLARTALESRS--DTDEPETETQRTLADALAEVFGGVSP 1015

Query: 987  HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQD-APA 1045
             IDDD F  G+DSIVAI+L   AR +GL V  RM+ ++ TIR L AAIDA  D  D A  
Sbjct: 1016 GIDDDFFDLGLDSIVAIALAAAARARGLGVSVRMIASSPTIRDLAAAIDAGGDETDEADG 1075

Query: 1046 DADYGAVRPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSIL 1105
              D G + PLP  +W++  G++RR +HTVLL  P+ +    +E ++Q LLD H  LRS +
Sbjct: 1076 TDDLGEITPLPYPAWMFRQGSHRRLSHTVLLCAPADLTVDVLETIIQTLLDTHPVLRSSV 1135

Query: 1106 TETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVR 1165
             +T  GPR V      V A  ++  +  P G   E+   V  AA    D+IDP  G ++R
Sbjct: 1136 IDTERGPRQVIGARGTVAASGIVREV--PAGDIAEVRRRVLFAA----DEIDPRTGDVMR 1189

Query: 1166 AIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKI-LPEFTS 1224
                RG        +++ +T HHLA+DVVSW +++ +LA  ++ + +G    +  P  TS
Sbjct: 1190 VGLLRG----VPGGDLVAITIHHLAIDVVSWSLVIPELAQRYQQVCSGGDISVGRPVGTS 1245

Query: 1225 YRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVD 1284
            YRRWC ++   A +P++  Q  +W A +   D A       P R  W  ++ T A     
Sbjct: 1246 YRRWCAVLDEYARSPELAAQEAFWTAQL--DDAATATETSGPLR--WGDVRTTEAGSTPA 1301

Query: 1285 VTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDT 1344
             T  +L A     G+RELLL A  + + +WRR +      GV VALE HGR   +   D 
Sbjct: 1302 ETAALLAAA-GPGGIRELLLTALTLTLTTWRRQQGVH-GGGVTVALESHGRG-GIEALDV 1358

Query: 1345 TNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRY 1404
            + TVGWFT  +PVRLG       ++  +   V A  L  SV + L A+P DGL YGLLR 
Sbjct: 1359 SGTVGWFTTVYPVRLGDLTGVAQVDATDGSEVRA--LHDSVCAALAAVPGDGLGYGLLRD 1416

Query: 1405 VDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYL-DALPIDPEPDLPLRFALN 1463
            + GV  L  A +PQ++F+YLGR DLG      WS +T P L +A+P  PEPDL LRF LN
Sbjct: 1417 IAGVESLCSAPEPQVEFNYLGRFDLGLGTGGDWSPVTDPELSNAIPSSPEPDLTLRFPLN 1476

Query: 1464 LSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD 1512
            L   V    +G QL+  WRWS  +F+   ID L  LW+  ++A+A+  +
Sbjct: 1477 LVTAVQAGDDGPQLVTTWRWSSVLFDAEQIDDLARLWRTHVSAVASAFE 1525


>tr|A1TBS5|A1TBS5_MYCVP Tax_Id=350058 SubName: Full=Amino acid
            adenylation domain; Flags: Precursor;[Mycobacterium
            vanbaalenii]
          Length = 1493

 Score = 1040 bits (2690), Expect = 0.0
 Identities = 638/1531 (41%), Positives = 851/1531 (55%), Gaps = 73/1531 (4%)

Query: 6    PQIEDVLALSPLQEGLFALHQLAED-GVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHP 64
            P IEDVLALSPLQ+GLF++  L+E    D Y +    D  G +D  LLR  A  +LDRH 
Sbjct: 11   PVIEDVLALSPLQQGLFSMATLSEGRDDDPYVIAMTADATGDLDARLLRECAAELLDRHA 70

Query: 65   NLRAAFWDRDVPKPVQIVPVHAALPWSE-RVATPAEFDSIARSERRRPFDLSRGPALRVV 123
            NLRA+F   ++ + VQ++P    LPW    VA  AE ++  R ER  PF L+RGP +R +
Sbjct: 71   NLRASFVKGNLSRAVQVIPKRVDLPWRHVTVAGDAELEAAERLERTTPFTLARGPVIRFL 130

Query: 124  VLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YIVWL 182
            ++  P   + R + TAHHIL+DGWSL +F  ELL +                   YI WL
Sbjct: 131  LIEAP--QRWRFVVTAHHILIDGWSLPLFMGELLTLYRAGGDVTALPDPPRPYRDYIGWL 188

Query: 183  AKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGK---TELLLPAADTARLRQWAGR 239
            A +D     A W  +L GV  P ++    T+    PG+   TE+ L A  T +L + A  
Sbjct: 189  AGRDEETGRALWRRHLAGVDGPTLLTPALTSSAPTPGRPRLTEVRLDAETTRQLAEAARS 248

Query: 240  HGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVS 299
             G+T+NT +  AWA VLS +TDR DV FG  VSGRP +L GVE MVGLFIN VP+   + 
Sbjct: 249  RGVTMNTLIQMAWATVLSVITDRTDVSFGVTVSGRPGELAGVERMVGLFINTVPLRVRLD 308

Query: 300  GTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPAT- 358
                   QC  +QR+++A+RD  YLS SE++   G G LFD+L V+EN P    +  A  
Sbjct: 309  PAAPAGEQCLALQREAAALRDHGYLSHSELRALGGIGELFDTLLVYENFPPGGLVGQARF 368

Query: 359  TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQ 418
              +GA F+P  +ESL+H+P+T+ +HL                  L   ++G R+L   ++
Sbjct: 369  EANGATFVPSALESLSHFPVTIAAHLADDELTVFVEVIDGALGALRPGDLGRRVLHTAQR 428

Query: 419  LPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXG 478
            L    D     + +   AE   H        P    ++ + F                 G
Sbjct: 429  LISCWDAPLRSVGVLLPAE---HTPAPMVREPLTANSIHDRFAGIAGDRLGSVALTWEAG 485

Query: 479  VRH---TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPV 535
                  TY +L   A R+A  L   GVGPET VA++L R                  +P+
Sbjct: 486  GDSGTLTYRQLDEAADRMAVALTAAGVGPETSVAVLLSRGPDYVVTMLGVLKAGGVIVPL 545

Query: 536  DVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVD 595
            D  +P+ R+  I+ Q+  ++ + +A  +     AVP +  + PA          A  T D
Sbjct: 546  DPAMPAERISDILEQSRASVVVDDAFVA-----AVPDV--EPPAGYRP------AEVTAD 592

Query: 596  RRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSL 655
            R    +AY++FTSG+TG PKGVVGT+ AVL Y  DHAE+V               HAWS 
Sbjct: 593  R----AAYIVFTSGTTGRPKGVVGTHGAVLGYAEDHAEQVLRPAAARIGRPLRVGHAWSF 648

Query: 656  SFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLL 715
            +FDA+WQP+  LLDGH +HL   E  RDA+ LV  I    IDM+DTTPSMF QL   GLL
Sbjct: 649  TFDAAWQPLAALLDGHSVHLLGEESQRDAEALVYRIGRFGIDMLDTTPSMFAQLHDVGLL 708

Query: 716  DH-NLSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTI 771
                L+VLALGGEA++   W  +      + M  +NCYGPTE TVE        Y++P+I
Sbjct: 709  STVPLAVLALGGEAVSPATWRLIGDECARTGMTAFNCYGPTETTVEAVVAPIDGYQRPSI 768

Query: 772  GTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRM 831
            G        YV D+ LR VPDGV GELYLSG QL RGY+GR   TA RFVADP  PGQRM
Sbjct: 769  GQPTRTMRTYVLDAWLRPVPDGVAGELYLSGRQLTRGYLGRAAETAGRFVADPFTPGQRM 828

Query: 832  YRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDR 891
            YRTGD+VRR + GG  ++GRAD QVKIRG+RVE GEI A L G P V DA V V R   +
Sbjct: 829  YRTGDVVRRGADGGLQFLGRADNQVKIRGFRVEPGEIAAVLSGHPAVTDAHVVVDRVGTQ 888

Query: 892  TSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLA 951
            T L+ +V         +  LR  + +RLP YMVP R+V L  LP+ ++GK+D  AL  +A
Sbjct: 889  TRLIAYVA--AATPPAVADLRELMAKRLPRYMVPQRVVVLDELPLTSHGKIDEAALAGIA 946

Query: 952  EDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVHKAR 1010
                  V    + +  T TE  L EL  E L +    ++ D    G+DSIVA++LV  AR
Sbjct: 947  ------VEDAPSAAPETPTETALVELMAEVLGDDGIDVEADFLEMGLDSIVALTLVQAAR 1000

Query: 1011 RQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPA---DADYGAVRPLPMVSWLYEYGNY 1067
            R+GL +  R++L   TIR+L  AID+      APA   D  +G V P P++SW+YE GNY
Sbjct: 1001 RRGLEMRARLMLECNTIRELATAIDSGAHDH-APAAVTDDRFGEVMPAPIMSWMYECGNY 1059

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDV 1127
            RRFT  VL+ LP+ I  S +E +LQ LLD HD LR+IL E     RLVTR P AVR  DV
Sbjct: 1060 RRFTQNVLVSLPADITDSRLEQILQALLDRHDMLRAILDER---GRLVTRPPGAVRVADV 1116

Query: 1128 LTRITLPEGSDDELASAVAHAARVVT--DQIDPSAGAMVRAIWFRGTEHRADPANILLLT 1185
            L  +        + A+    AA VV   D+IDP++GAMV+A+WFR       P  +L L 
Sbjct: 1117 LRVV--------DAAAHTVLAAEVVAALDRIDPTSGAMVQAVWFR----HGPP--VLALC 1162

Query: 1186 AHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQR 1245
             HHL+ DVVSW+++LG LA    +L AG  P    E+T+YR W   ++ R+    V+ +R
Sbjct: 1163 VHHLSTDVVSWYLILGALAQIDATLAAGHAPDPAAEYTTYREWTRRLYQRSRTEAVERRR 1222

Query: 1246 DYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAV-RRDQGVRELLL 1304
             +W   +   DP LG R PDP  DTWSTLQ T        T  +L  +      VR+ LL
Sbjct: 1223 GFWVEQLAGSDPLLGRRLPDPRHDTWSTLQSTDVVTDAGATRAILDRLDGASLEVRDFLL 1282

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL--DTDTTNTVGWFTNAFPVRLGAG 1362
             A  + +ASWR  R Q    G LVALEGHGR DA++    DT+ TVGWFT+ +PVRLGAG
Sbjct: 1283 TALTLTLASWRIERGQPAHHGALVALEGHGREDALVGGGVDTSATVGWFTSVYPVRLGAG 1342

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFS 1422
             AA+D++ A R+P AA+ L+ +V+  L  +P+ GLDYGLLRY      L    +PQ++F+
Sbjct: 1343 EAAIDVDTAARNPAAARSLLRAVIQQLAEVPDKGLDYGLLRYTRRDETLRALPEPQVEFN 1402

Query: 1423 YLGRLDLGG-VADQPWSLLTGPYLDA-LPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
            Y+GR DL      Q WSL+T   L+A +P   EPDLPLR+  ++   +   A+G QL  +
Sbjct: 1403 YIGRYDLSADQTSQAWSLITDETLNAHMPAAAEPDLPLRYTFDVISVISGGADGPQLRTS 1462

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAAGL 1511
            WRWS A+   +++D LT LWQ+ +  L   L
Sbjct: 1463 WRWSTALSTSTEVDRLTALWQQAVTVLGEAL 1493


>tr|A0QE95|A0QE95_MYCA1 Tax_Id=243243 SubName: Full=Putative
            sulfotransferase;[Mycobacterium avium]
          Length = 1480

 Score =  935 bits (2416), Expect = 0.0
 Identities = 611/1532 (39%), Positives = 810/1532 (52%), Gaps = 99/1532 (6%)

Query: 2    TAAAPQIEDVLALSPLQEGLFALHQLAE--DGV---DLYSMQFVVDIDGPVDLELLRRSA 56
            T  AP IEDV+ALSPLQEGL++L  LAE  DG    D Y +    DI G +D+ LLR  A
Sbjct: 6    TDVAPDIEDVMALSPLQEGLYSLTTLAEFADGQPADDPYVIGMAADITGTLDVALLRDCA 65

Query: 57   QAMLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSR 116
            + ML RHPNLRA+F+ R +P+PVQIVP    LPW    A+PAE   +  +ERRRPFDL R
Sbjct: 66   EKMLVRHPNLRASFFSRGIPRPVQIVPSRVELPWRSVTASPAEVPMLETAERRRPFDLER 125

Query: 117  GPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXX 176
            GPA+R +++ +P +   R++ TAHHI++DGWSL VF  EL+ +                 
Sbjct: 126  GPAIRFLLIELP-DAHWRLVLTAHHIVIDGWSLPVFVNELMTLYRAGGDRSALPAAPRPY 184

Query: 177  X-YIVWLAKQDRSAALAGWMDYLRGVSEPLMVAY-----EATAGQ--SKPGKTELLLPAA 228
              YI WLA +D  A+   W ++L G+  P ++A      EAT GQ  + P  TEL +PA 
Sbjct: 185  RDYIGWLAGRDLQASQRVWREHLAGLPGPTLLAASLGSAEATGGQRTALPRTTELRMPAE 244

Query: 229  DTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLF 288
             TARL       G+T+NT +  AWA+VLSRLTD RDVVFG  VSGRP +L GVETMVGLF
Sbjct: 245  ATARLAAETRSRGITVNTLMQMAWALVLSRLTDTRDVVFGVTVSGRPPELTGVETMVGLF 304

Query: 289  INAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENA 348
            IN VP+   +     V  QC  VQR ++ +R+ SYL  ++++   G G +FD+L V+EN 
Sbjct: 305  INTVPLRVRLDPAATVGEQCRAVQRDAALLREHSYLGHAQLRALGGIGEMFDTLLVYENF 364

Query: 349  PIDDAIRPAT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAE 407
            P+D        +  GA F P  +++L+H+P+ V +H+                  +PA  
Sbjct: 365  PMDGLTAGGELSAGGATFRPSALQTLSHFPIAVAAHMEGGELVVLIEVVDGALGVIPADA 424

Query: 408  IGERMLTVLRQLPDIGDGTPDDLDIR---TAAELKAHGLLAARSAPTFDTTVWEMFERQV 464
            +G R+LT   +L    +     + +     AA L+A G +A  S         ++  +  
Sbjct: 425  VGRRLLTTAERLLRHWERPLRAVSVLFDDEAAPLRAAGPIAPPSPKCLPARFADVVAQTP 484

Query: 465  QXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXX 524
                             TY EL     RLA +L   GV PET VA+ L R  R       
Sbjct: 485  DAPAVSWAQGSL-----TYRELDEATNRLAAQLVALGVEPETPVAIKLSRGPRYVVAMLA 539

Query: 525  XXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESI 584
                    +P++  +P+ RV SI+RQ+  ++ + E    +L+               E+ 
Sbjct: 540  VLKAGGMCVPMEPGMPAPRVNSILRQSGASIVLDEERIDELL---------------EAG 584

Query: 585  SRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXX 644
              +       D  P Q+AYV+FTSG+TGEPKGV+GT+ AV +Y  DH +RV         
Sbjct: 585  RSQHGGFEPPDIPPAQAAYVVFTSGTTGEPKGVIGTHGAVGAYADDHLDRVLRPAAAALG 644

Query: 645  XXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPS 704
                  HAWS +FDA+WQP+V LLDGH +H+ D     DA+ LV  IA   +DMIDTTPS
Sbjct: 645  RPLRIAHAWSFAFDAAWQPLVALLDGHGVHVVDEATQTDAEALVALIAEHGVDMIDTTPS 704

Query: 705  MFVQLSAAGLLDHN-LSVLALGGEAINTGLWDQLRGL---SQMAVYNCYGPTEMTVEXXX 760
            MF QL A GLL    L+VLALGGEA+    W ++R     + M+ YNCYGPTE TVE   
Sbjct: 705  MFAQLQAFGLLSEAPLTVLALGGEALGNAAWARIRNACNTTTMSAYNCYGPTETTVEAVV 764

Query: 761  XXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARF 820
                ++ +P+IG     T GYV DS LR VP G  GELYL GAQLARGY+GR G TA+RF
Sbjct: 765  AAIAEHAEPSIGRPTRHTRGYVLDSELRPVPCGATGELYLGGAQLARGYLGRAGETASRF 824

Query: 821  VADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHD 880
            VADP    +RMYRTGDLVRRL  G   YVGRAD QVKIRG+RVE GEI AAL   P V  
Sbjct: 825  VADPFAASERMYRTGDLVRRLPDGSLQYVGRADAQVKIRGHRVEPGEIAAALESHPAVRH 884

Query: 881  AAVSVLRQQDRTSLVGFVVWQDNMHE--DLIKLRAGLTERLPSYMVPARIVTLPRLPVNA 938
            A V V  +     L G+V   +   +     +LR  L+ RLP YMVP RI+ +  +P+  
Sbjct: 885  AGVLVRHRDGAPRLTGYVATHEAAPDTPSPAELRGMLSARLPRYMVPQRIIMVDEIPLTP 944

Query: 939  NGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPHID--DDLFLFG 996
            NGKLD  AL   A D   +V G  A +  T TE  L EL  E L   P +D   D    G
Sbjct: 945  NGKLDETAL--AAVDNAEAVDG--AATPQTGTESALAELIAELLGQ-PRVDVTADFLALG 999

Query: 997  MDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLP 1056
            +DSI+A+S+V  AR +G+ +  R+VL  T+IR+L  AIDA         D   G +  LP
Sbjct: 1000 LDSIMALSVVQAARARGIALRARLVLDCTSIRELAEAIDAESTPAAGEVDDGTGPMPLLP 1059

Query: 1057 MVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVT 1116
               WLYE+G  RR   T  +R+P  + R  +E  L  ++DGH+ LRS +         +T
Sbjct: 1060 NGRWLYEHGQPRRLAQTEAIRVPQTLRRDQLETALAGIIDGHEVLRSRVDRA-----TMT 1114

Query: 1117 REPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRA 1176
              P    A D+   +       D  A+    AAR + D++DP  G ++ A+W R     A
Sbjct: 1115 LVPGP--APDIGKELEEVAVVGDLRAAVADRAARAI-DRLDPERGVLLGAVWLR----PA 1167

Query: 1177 DPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRA 1236
            D   +LLLTAH +A+D  SW ++LG+L AA  +   G  P  + E TSYRRW   +  RA
Sbjct: 1168 DGDGVLLLTAHVIALDPASWRVVLGELGAALTAAATGHSPAAVREHTSYRRWAHALTARA 1227

Query: 1237 SAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRD 1296
                  D   +WA+ +   DP LG R  DP RD    L +   A   D+T R+L      
Sbjct: 1228 HR---LDTVGFWASELDGDDPDLGARRVDPARDRARDLLVRNVATDADLTRRLL---ESG 1281

Query: 1297 QGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD------TDTTNTVGW 1350
              +  LL+AATA  V  WRR R Q      L+ALE HGRAD+++D       DT +TVG 
Sbjct: 1282 LPLPTLLVAATAATVTRWRRQRGQS-TPPPLLALETHGRADSLVDGPGAHTIDTGDTVGL 1340

Query: 1351 FTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV-DGVA 1409
             ++ +P+R+ A            DP         V   L AIP DGLDYGLLRY+ D  A
Sbjct: 1341 LSSIYPIRVDAA-----------DP-------RRVADKLAAIPGDGLDYGLLRYLRDDTA 1382

Query: 1410 ELVDAV-DPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFV 1468
            E + A+  PQ+  +YLG     G        L    L  L   PEPDL +R  L ++  V
Sbjct: 1383 ERLAALPSPQLLLNYLGAAHTDGGTG---LTLERELLAGLSPIPEPDLAVRHELTIAAMV 1439

Query: 1469 GVTAEGTQLIGNWRWSDAVFERSDIDHLTGLW 1500
                    L   WR    +   +DI  L  LW
Sbjct: 1440 LTYGGQRVLAAQWRTLPDILTDTDITALQELW 1471


>tr|A0R0U4|A0R0U4_MYCS2 Tax_Id=246196 SubName: Full=Peptide synthetase
            mbtf;[Mycobacterium smegmatis]
          Length = 1479

 Score =  915 bits (2366), Expect = 0.0
 Identities = 609/1549 (39%), Positives = 817/1549 (52%), Gaps = 132/1549 (8%)

Query: 2    TAAAPQIEDVLALSPLQEGLFALHQLAED--GVDLYSMQFVVDIDGPVDLELLRRSAQAM 59
            T   P IEDVLALSPLQ+GL++L  L E+  G D Y +    DI+G VD  LLR  A+AM
Sbjct: 4    TGTPPGIEDVLALSPLQQGLYSLAGLTEEDTGADPYVIAMAADIEGAVDPALLRSCAEAM 63

Query: 60   LDRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDS-IARSERRRPFDLSRGP 118
            L RHPNLRA+F+  ++ +PV +VP    LPW    A  AE  + I   ER R FDL RGP
Sbjct: 64   LVRHPNLRASFFQGNLTRPVAVVPTAVDLPWRHVTAPTAEAAAAIEAEERTRRFDLGRGP 123

Query: 119  ALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX- 177
             +R +++ +P + + R++ TAHHI +DGWSL VF  E + +                   
Sbjct: 124  LIRFLLIEMPAQ-RWRLVVTAHHIAIDGWSLPVFVGEYITLYAADGDTAVFPAAPRPYRD 182

Query: 178  YIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPG---KTELLLPAADTARLR 234
            YI WLA +D  A+ A W  +L G+  P ++A   +  +++PG   +TE+ L    +A + 
Sbjct: 183  YIGWLAGRDHDASRARWRAHLDGLDGPTLLAPALSGREAEPGLPARTEVTLDEQASAEIF 242

Query: 235  QWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPV 294
              A   G+T+NT    AWA +LS  TDR DVV+G  VSGRPD+L GVE+MVGLFIN VP+
Sbjct: 243  DGARARGVTVNTLFQMAWAAILSAFTDRTDVVYGVTVSGRPDELSGVESMVGLFINTVPL 302

Query: 295  VHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAI 354
               +    +V  QC  VQR+++ +RD SYLS +EI+   G G LFD+L V+EN P    +
Sbjct: 303  RIRLDPAGSVGEQCLAVQREAADLRDHSYLSHTEIRALGGIGELFDTLLVYENFPPGGLV 362

Query: 355  RPATTP-----DGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIG 409
                 P     DGA   P  +ESL+H+P+T+ +H                   L    +G
Sbjct: 363  GSDEFPLGSDGDGAVLRPSALESLSHFPVTIAAHPTHGRLTVLVETLDGALGMLDPHALG 422

Query: 410  ERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTV----WEMFERQVQ 465
             R+LTV+++L    D    D+ +    E+       A  APT DT V    +     +  
Sbjct: 423  RRVLTVVQRLLRSWDRPVRDVAVTLDDEV-------ATVAPT-DTAVRPGGFHTAFTEAA 474

Query: 466  XXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXX 525
                        G   TY +L   A R+A EL   GVG ET V + LPR           
Sbjct: 475  AQRLGSIALTWDGGELTYRQLDEAADRVAAELRRRGVGTETPVPIRLPRGPEYVVAMLGV 534

Query: 526  XXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESIS 585
                   +P+D  +P  RV+ I+RQ  P       D  Q         A+ D A V ++ 
Sbjct: 535  LKAGGLIVPLDPAMPDERVDEIIRQTHP-------DGRQP--------AIVDDAFVAAVR 579

Query: 586  RRSAAAPTVDR----RPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXX 641
               A  P   R     P Q AY++FTSG+TG+PKGV+GT+ A+L+Y ADHA  V      
Sbjct: 580  AADAELPADYRPAHVHPGQGAYIVFTSGTTGKPKGVIGTHQALLAYAADHARNVLRPAAQ 639

Query: 642  XXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDT 701
                     HAWS +FDA+WQP+V LLDGH  H+   +  RDA+ LVE I    IDMIDT
Sbjct: 640  RVGHPLRVAHAWSFTFDAAWQPLVALLDGHANHIVGDDVQRDAEALVETIGRHAIDMIDT 699

Query: 702  TPSMFVQLSAAGLLDH-NLSVLALGGEAINTGLWDQLRGLSQ---MAVYNCYGPTEMTVE 757
            TPSMF QL AAGLL    L+VLALGGEAI+T LW  ++   +   M+ +NCYGPTE TVE
Sbjct: 700  TPSMFTQLRAAGLLSTVPLAVLALGGEAIDTALWQAIQAECERTWMSAHNCYGPTEATVE 759

Query: 758  XXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTA 817
                   D+R P IG     T  YV DS LR VP GV GELYL+G QL RGYVGRPG TA
Sbjct: 760  AVVAAIADHRDPCIGKPTDPTAAYVLDSWLRPVPAGVAGELYLAGGQLTRGYVGRPGETA 819

Query: 818  ARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPG 877
            ARFVADP   G RMYRTGD+VRR   G   ++GR+D QVKIRG+RVE GE+ AAL   P 
Sbjct: 820  ARFVADPFTLGARMYRTGDVVRRTPDGALQFLGRSDDQVKIRGFRVEPGEVAAALHRHPQ 879

Query: 878  VHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVN 937
            V  A V++ R +    LV +VV   ++ +   +LR  L   LP Y+VP  I+ +  +P+ 
Sbjct: 880  VRHAHVALRRHRSGPRLVAYVVTDASLADAAGELRRMLAATLPRYLVPHHILLVDEIPLT 939

Query: 938  ANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFG 996
             NGK+D     RLA       SGG     +TDTERV+ E+  E L+     +  +    G
Sbjct: 940  TNGKVDD---ARLAALDSGRQSGGFQ-GPATDTERVVAEVLAEVLDTRAVDVTAEFLDLG 995

Query: 997  MDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD---ADYGAVR 1053
            +DSIVA+++V   RR+GL +  R++L    +R+L AAIDA  D+  A  D    D G + 
Sbjct: 996  LDSIVALTVVQAVRRRGLALRARLMLECANVRELAAAIDA--DAHHAAVDHTPEDSGPIP 1053

Query: 1054 PLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSIL-----TET 1108
             LP  SWLY+YG  RR   T   RLP G   + +  +L+ ++DGH+ LR+ L     T  
Sbjct: 1054 LLPNGSWLYQYGEPRRLAQTEAFRLPEGTTAAQLRTLLRTVVDGHEVLRTRLDRVTRTLV 1113

Query: 1109 PEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIW 1168
            P GPR V  E   V                  LA AVA  A +  D+IDP  G+M+ A+W
Sbjct: 1114 PHGPRDVLTEAVGV----------------GTLADAVAEQAALSVDRIDPQQGSMLDAVW 1157

Query: 1169 FRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRW 1228
             R   H   P  + +LTAH LA+D  SW I++G+L  AW +L +G  P  + E TS RRW
Sbjct: 1158 LR---HPDAPGGVFILTAHVLALDPASWRIVVGELETAWHALASGREPTPVREHTSLRRW 1214

Query: 1229 CELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTER 1288
              ++  RA      D  D+W       DP +G R  DP  D    + +       D+T R
Sbjct: 1215 SRMLSERALK---LDTVDFWHRQFDGADPDIGARRVDPATDRMRDIAVEMTFADADLTAR 1271

Query: 1289 VL-GAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL------- 1340
            +L G V     V E+L AATA  V +WRR R Q P    L+ALE HGRADAV+       
Sbjct: 1272 LLTGGV----PVTEVLAAATARTVTAWRRERGQ-PTPAPLLALETHGRADAVVSADLGED 1326

Query: 1341 --DTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLD 1398
                DT +T G  +  +P+R+ AG A                    V   + AIP D +D
Sbjct: 1327 PHQVDTGDTAGLLSMIYPLRVTAGDA------------------RGVAELVAAIPGDPID 1368

Query: 1399 YGLLRYV--DGVAELVDAVDPQIQFSYLGRLDLGGVAD----QPWSLLTGPYLDALPIDP 1452
            YGLLR++  D    L    DPQ+  +YLGR++L   AD    Q  SLL+G      PI P
Sbjct: 1369 YGLLRHLREDTAESLGVHRDPQLLLNYLGRIELDS-ADHALLQDRSLLSG----VTPI-P 1422

Query: 1453 EPDLPLRFALNLSVFVGVTAEGTQLIG-NWRWSDAVFERSDIDHLTGLW 1500
            EPD+ +R  L +   V +  +G+ ++G  WR    +   +++  L  +W
Sbjct: 1423 EPDVAVRHELTIMAAV-IDRDGSAVLGAQWRTLPDILSAAEVGTLQTMW 1470


>tr|Q7TYQ8|Q7TYQ8_MYCBO Tax_Id=1765 (mbtF)SubName: Full=PEPTIDE
            SYNTHETASE MBTF (PEPTIDE SYNTHASE);[Mycobacterium bovis]
          Length = 1461

 Score =  895 bits (2312), Expect = 0.0
 Identities = 592/1529 (38%), Positives = 797/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L+D  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEDDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA     V   +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGVLASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|C1AQU2|C1AQU2_MYCBT Tax_Id=561275 (mbtF)SubName: Full=Peptide
            synthetase;[Mycobacterium bovis]
          Length = 1461

 Score =  895 bits (2312), Expect = 0.0
 Identities = 592/1529 (38%), Positives = 797/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L+D  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEDDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA     V   +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGVLASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|A1KL69|A1KL69_MYCBP Tax_Id=410289 (mbtF)SubName: Full=Peptide
            synthetase mbtF;[Mycobacterium bovis]
          Length = 1461

 Score =  895 bits (2312), Expect = 0.0
 Identities = 592/1529 (38%), Positives = 797/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L+D  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEDDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA     V   +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGVLASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|A5WPZ4|A5WPZ4_MYCTF Tax_Id=336982 SubName: Full=Peptide synthetase
            mbtF;[Mycobacterium tuberculosis]
          Length = 1461

 Score =  895 bits (2312), Expect = 0.0
 Identities = 591/1529 (38%), Positives = 797/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L+D  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEDDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR+VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRLVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA         +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGALASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|C6DNA5|C6DNA5_MYCTK Tax_Id=478434 SubName: Full=Peptide synthetase
            mbtF;[Mycobacterium tuberculosis]
          Length = 1461

 Score =  893 bits (2308), Expect = 0.0
 Identities = 591/1529 (38%), Positives = 796/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L+D  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEDDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA         +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGALASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|Q7D792|Q7D792_MYCTU Tax_Id=1773 SubName: Full=Peptide
            synthetase;[Mycobacterium tuberculosis]
          Length = 1461

 Score =  893 bits (2308), Expect = 0.0
 Identities = 591/1529 (38%), Positives = 796/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L+D  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEDDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA         +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGALASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|A4KJC9|A4KJC9_MYCTU Tax_Id=395095 SubName: Full=Peptide synthetase
            mbtF;[Mycobacterium tuberculosis str. Haarlem]
          Length = 1461

 Score =  893 bits (2308), Expect = 0.0
 Identities = 591/1529 (38%), Positives = 796/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L+D  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEDDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA         +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGALASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|A2VKA5|A2VKA5_MYCTU Tax_Id=348776 SubName: Full=Peptide synthetase
            mbtF;[Mycobacterium tuberculosis C]
          Length = 1461

 Score =  893 bits (2308), Expect = 0.0
 Identities = 591/1529 (38%), Positives = 796/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L+D  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEDDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA         +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGALASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|O05819|O05819_MYCTU Tax_Id=1773 (mbtF)SubName: Full=PEPTIDE
            SYNTHETASE MBTF (PEPTIDE SYNTHASE);[Mycobacterium
            tuberculosis]
          Length = 1461

 Score =  892 bits (2304), Expect = 0.0
 Identities = 590/1529 (38%), Positives = 796/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L++  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEEDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA         +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGALASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|A5U572|A5U572_MYCTA Tax_Id=419947 (mbtF)SubName: Full=Peptide
            synthetase;[Mycobacterium tuberculosis]
          Length = 1461

 Score =  892 bits (2304), Expect = 0.0
 Identities = 590/1529 (38%), Positives = 796/1529 (52%), Gaps = 109/1529 (7%)

Query: 8    IEDVLALSPLQEGLFALHQL--AEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            I+DV+ALSPLQ+GLF+   L  AE G      D Y +    D  GP+D+ LLR  A AML
Sbjct: 15   IDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAML 74

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPAL 120
             RHPNLRA+F   ++ +PVQ++P  A + W    A P+E  ++A  ERRR FD+ RGP +
Sbjct: 75   TRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLI 134

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R +++ +P E    ++  AHHI++DGWSL +F +ELLA+                   YI
Sbjct: 135  RFLLIELPDECWH-LVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYI 193

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVA---YEATAGQSKPGKTELLLPAADTARLRQW 236
             WLA +D++A+ A W D+L G+  P +++    +       PG+TE+ L    TA L   
Sbjct: 194  GWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADA 253

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T++T V  AWA  LS  T R DV FG  VSGRP +L GVETM+GLFIN VP+  
Sbjct: 254  ARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRV 313

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             +     V  QC  +QRQ + +RD SYL  +E +   G G +FD+L V+EN P  + +  
Sbjct: 314  RLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGT 373

Query: 357  AT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A    +G  F PV +ESL+H+P+TV +H                   +    +G R+L V
Sbjct: 374  AEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAV 433

Query: 416  LRQLPDIGDGTPDDLDIRTAAELK--AHGLL-AARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L++L    D    D+DI    E    A GL     SAP   T   E+   Q         
Sbjct: 434  LQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWA 493

Query: 473  XXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXY 532
                     TY EL A A RLA  L    V  ET VA+ L R  R               
Sbjct: 494  DGQL-----TYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMI 548

Query: 533  LPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAP 592
            +P+D  +P  RV  I+RQ S  + I E  ++  VG  +    L++  A+          P
Sbjct: 549  VPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADI----LEEDRAI--------TVP 596

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
                  +Q+AYVIFTSG+TG PKGV+GT+ A+ +Y  DH ERV               HA
Sbjct: 597  V-----DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHA 651

Query: 653  WSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
            WS +FDA+WQP+V LLDGH +H+ D    RDA  LVE I    +DMIDTTPSMF QL  A
Sbjct: 652  WSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNA 711

Query: 713  GLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRK 768
            GLLD   L+VLALGGEA+    W  ++     + M  +NCYGPTE TVE       ++ +
Sbjct: 712  GLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHAR 771

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG 828
            P IG     T  YV DS LR VPDGV GELYL+GAQL RGY+GRP  TAARFVA+P   G
Sbjct: 772  PVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRG 831

Query: 829  QRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ 888
             RMYRTGD+VRRL  GG  ++GR+D QVKIRG+RVE GEI A L G   VH   V+    
Sbjct: 832  SRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGH 891

Query: 889  QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
                 L  +V         + +LRA L ERLP Y+VP  IV L  LP+  +GK+D +AL 
Sbjct: 892  ASGPRLTAYVA-GGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENAL- 949

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVH 1007
                 A  +V+ G A    T TE VL E F + +  +   +       G+DSIVA+S+V 
Sbjct: 950  -----AAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQ 1004

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNY 1067
             ARR+G+ +  R+++   TIR+L AAID+    Q APA+     +  LP   WLYEYG+ 
Sbjct: 1005 AARRRGIALRARLMVECDTIRELAAAIDSDAAWQ-APANDAGEPIPVLPNTHWLYEYGDP 1063

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAE-- 1125
            RR   T ++RLP  I R  ++ +L  ++DGH+ LR              R+  A+ A+  
Sbjct: 1064 RRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRC----------RFDRDAMALVAQPK 1113

Query: 1126 -DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
             D+L+ + +      EL +AVA         +DP AG ++ A+W R      D   +L+L
Sbjct: 1114 TDILSEVWV----SGELVTAVAEQTLGALASLDPQAGRLLSAVWLR----EPDGPGVLVL 1165

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ 1244
            TAH LA+D  SW I+LG+L A   +L AG  P    E TSYR+W  L+  RA A    D 
Sbjct: 1166 TAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKA---LDS 1222

Query: 1245 RDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLL 1304
             D+W A +   DP LG R   P  D    L +T +    D+T R+L   R    + +LL 
Sbjct: 1223 VDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGR---SMTDLLA 1279

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD--TDTTNTVGWFTNAFPVRLGAG 1362
             A A  V +WRR R Q   A  L+ALE HGRAD  +D   DT++TVG  +  +P+R+   
Sbjct: 1280 TAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCD 1338

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQ 1420
             A                      +    IP  G+DYGLLRY+  D    L    +PQ+ 
Sbjct: 1339 GA----------------------TDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLL 1376

Query: 1421 FSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGN 1480
             +YLG L + GV D     +    L  +   PEP+ P+R  L +   +   A+   L   
Sbjct: 1377 LNYLGSLHV-GVGD---LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATR 1432

Query: 1481 WRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            WR    +    D+  L  LWQ  +A + A
Sbjct: 1433 WRTLPDILSADDVATLQSLWQGALAEITA 1461


>tr|A3Q277|A3Q277_MYCSJ Tax_Id=164757 SubName: Full=Amino acid
            adenylation domain;[Mycobacterium sp.]
          Length = 1460

 Score =  887 bits (2291), Expect = 0.0
 Identities = 575/1534 (37%), Positives = 803/1534 (52%), Gaps = 108/1534 (7%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAE----DG---VDLYSMQFVVDIDGPVDLELLRRS 55
            AAA  IEDV+ALSPLQ+GL+++  LA+    DG    D Y +    D+ G +D  LLR  
Sbjct: 6    AAANAIEDVMALSPLQQGLYSMTMLADSEHADGDPRPDPYVIAMAADVTGTLDTALLRDC 65

Query: 56   AQAMLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWSE-RVATPAEFDSIARSERRRPFDL 114
            A A+L RHPNLRA F+  D+P+PVQ+VP    LPW   R  T  E   +   ERRRPFDL
Sbjct: 66   ATALLTRHPNLRAGFFRGDLPRPVQVVPARVDLPWQHVRARTAEEAAELEHRERRRPFDL 125

Query: 115  SRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXX 174
             RGPA+R +++ +PG   R ++  AHHI++DGWSL +F  ELL +               
Sbjct: 126  ERGPAIRFLLIELPGPAWR-LVIVAHHIVIDGWSLPLFVGELLTLYRAGGDPGALGDPPR 184

Query: 175  XXX-YIVWLAKQDRSAALAGWMDYLRGVSEPLMV-----AYEATAGQSKPGKTELLLPAA 228
                YI WLA +D++A+ A W ++L G+  P ++     A E  AG   P +TE+ L A 
Sbjct: 185  PYRDYIGWLAGRDQAASRALWTEHLAGIDAPTLLTPALSAVEPAAGL--PRRTEVALDAG 242

Query: 229  DTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLF 288
             + RL + A   G+T+NT V  AWA +LS  TDRRDV FG  VSGRP +L GVETMVGLF
Sbjct: 243  ASRRLTETARSRGVTVNTLVQMAWAAMLSVFTDRRDVTFGMTVSGRPGELAGVETMVGLF 302

Query: 289  INAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENA 348
            IN VP+   +   + V +QC  +QR ++A+R+ SYL+ SE++   G G +FDSL V+EN 
Sbjct: 303  INTVPLRVRLDPVDTVGSQCLSLQRTAAALREHSYLAHSELRALAGVGEMFDSLLVYENF 362

Query: 349  PIDDAIRPATTPD--GAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAA 406
            P    +      +  GA F+P  +ESL+H+P+T+ +H+                  L   
Sbjct: 363  PPGGLVGGDHRFEAAGATFIPAALESLSHFPVTIAAHMADERLTVLVETLDGALGALTPH 422

Query: 407  EIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQX 466
            ++G+ +L  + +L  + D    D+ I    +      + A + P   T V   F    + 
Sbjct: 423  DVGQGLLDTVERLIALWDRPLRDVRILFGDD----PAVPAVTEPPPRTGVHCAFTEAARR 478

Query: 467  XXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXX 526
                       G   TY E+ A A RLA  L   GVG ET VA+ L R            
Sbjct: 479  TPDAVALSWDGGTL-TYREVDAAADRLAAGLTARGVGAETPVAVRLSRGPDYVIAMLAVL 537

Query: 527  XXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISR 586
                  +P+D  +   R+E I+RQ +  + +         G   P  A   PA V     
Sbjct: 538  KAGGMIVPLDPGMAGERIEEILRQTAAPVVVDALS----AGVGAPDGAWA-PATVA---- 588

Query: 587  RSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXX 646
                       P Q+AY +FTSG+TG PKGVVGT+ AVL+Y  DHA  V           
Sbjct: 589  -----------PGQAAYAVFTSGTTGIPKGVVGTHDAVLAYADDHARHVLRPAATRLGRP 637

Query: 647  XXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMF 706
                HAWS +FDA+WQP+V L +GH +H+      RDA+ LV+ I    IDMIDTTPSMF
Sbjct: 638  LRIAHAWSFTFDAAWQPLVALFEGHSVHIIGDAVQRDAEALVDTIDRYDIDMIDTTPSMF 697

Query: 707  VQLSAAGLLDH-NLSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXX 762
             QL A GL+    L+VLALGGEA+ +G W  +R     + M  +NCYGPTE TVE     
Sbjct: 698  AQLKAFGLMSRVPLAVLALGGEAVGSGTWRFIREECARTSMTAFNCYGPTETTVEAVVAA 757

Query: 763  XKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVA 822
              ++ +P IG+       YV D+ LR +PDGV GELYLSGAQLARGY+ R   TA RFVA
Sbjct: 758  IAEHPQPVIGSPTRHARAYVLDAWLRPLPDGVAGELYLSGAQLARGYLDRASETAGRFVA 817

Query: 823  DPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAA 882
            DP   G RMYRTGD+VRR + G   Y+GR+D QVKIRG+RVE GE+ A L+  P V  A 
Sbjct: 818  DPFLAGNRMYRTGDVVRRDATGALQYLGRSDDQVKIRGFRVEPGEVCAVLQTHPAVRAAH 877

Query: 883  VSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKL 942
            V+V R      L  +          + +LR  L+ RLP Y+VP  I  L  LP+ A+GK+
Sbjct: 878  VAVRRHGAGPRLTAYAA-TGGTDVAVAELRHMLSTRLPRYLVPHHIAVLDELPLTAHGKI 936

Query: 943  DGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIV 1001
            D   L         + + G A +  T TE  L E   E L      ++ DL   GMDSIV
Sbjct: 937  DDATL-----ATYDAAAAGPAAAPETPTEAALAEAVAELLGTTAVDVNADLLSLGMDSIV 991

Query: 1002 AISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPM---V 1058
            A+S+V  ARR+G+ +  R++L   +IR+L  A+DA   ++ +    +  +  P+P+   V
Sbjct: 992  ALSVVQAARRRGVALRARLMLECGSIRELATAVDAEAGTESSSQATEAASSDPIPVLPNV 1051

Query: 1059 SWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTRE 1118
             WLYEYG+ RR   T  + LP GI   ++  +L+ +LDGH+ LR+    T     +    
Sbjct: 1052 HWLYEYGHPRRLAQTEAIPLPDGITADALRTVLRTVLDGHEVLRTRFDRT----AMTLVP 1107

Query: 1119 PAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADP 1178
             A   A+++L+ + +      +LA AVA        ++DP  G +  A+W R     A  
Sbjct: 1108 QAETPADELLSEVAV----SGDLADAVAEHTETAVQRLDPERGRLWSALWLR----PAHG 1159

Query: 1179 ANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASA 1238
              +L++TAH LA+D  SW +++G+L  AW +L+AG  P    E T+YR+W   +  RA  
Sbjct: 1160 PGVLVVTAHVLAIDPASWRVVIGELDTAWHALRAGRTPTPTREHTTYRQWSARVRERAHR 1219

Query: 1239 PQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQG 1298
                D  D+WAA +   DP LG R   P  D    L+++ A    D+T R++ +    Q 
Sbjct: 1220 ---LDTADFWAAQLDGADPELGARRVRPEADRARDLEVSVAITEPDLTARLIASA---QA 1273

Query: 1299 VRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL--DTDTTNTVGWFTNAFP 1356
            +  LL  A A  V +WRR R Q P    L+ALE HGRAD+ +  D DT +TVG F+  +P
Sbjct: 1274 MPTLLTLAAARTVTAWRRRRGQ-PTPPPLLALETHGRADSAVSADADTGDTVGLFSAIYP 1332

Query: 1357 VRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDA 1414
            VR+   A  V+                        IP +G+D+GLLRY+  D    L   
Sbjct: 1333 VRVDPDAGPVE------------------------IPGEGIDFGLLRYLRADTAERLCAY 1368

Query: 1415 VDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEG 1474
              PQ+  +YLGR D+GG     +++  G  L A+ + PEP+L +R  + +   +    + 
Sbjct: 1369 RQPQLLLNYLGRADVGGAG--TFNVDKG-LLRAVSVLPEPELAVRHEVTVMAAILPQGDA 1425

Query: 1475 TQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
              L   WR    V    D+  L  LWQ  +  +A
Sbjct: 1426 PVLATQWRTLPEVLSADDVAVLQTLWQDALQEVA 1459


>tr|Q1B6B2|Q1B6B2_MYCSS Tax_Id=164756 SubName: Full=Amino acid
            adenylation;[Mycobacterium sp.]
          Length = 1461

 Score =  885 bits (2288), Expect = 0.0
 Identities = 577/1534 (37%), Positives = 803/1534 (52%), Gaps = 107/1534 (6%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAE----DG---VDLYSMQFVVDIDGPVDLELLRRS 55
            AAA  IEDV+ALSPLQ+GL+++  LA+    DG    D Y +    D+ G +D  LLR  
Sbjct: 6    AAANAIEDVMALSPLQQGLYSMTMLADSEHADGDPRPDPYVIAMAADVTGTLDTALLRDC 65

Query: 56   AQAMLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWSE-RVATPAEFDSIARSERRRPFDL 114
            A A+L RHPNLRA F+  D+P+PVQ+VP    LPW   R  T  +   +   ERRRPFDL
Sbjct: 66   ATALLTRHPNLRAGFFRGDLPRPVQVVPARVDLPWQHVRARTAEKAAELEHRERRRPFDL 125

Query: 115  SRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXX 174
             RGPA+R +++ +PG   R ++  AHHI++DGWSL +F  E+L +               
Sbjct: 126  ERGPAIRFLLIELPGPAWR-LVIVAHHIVIDGWSLPLFVGEMLTLYRAGGDPGALGDPPR 184

Query: 175  XXX-YIVWLAKQDRSAALAGWMDYLRGVSEPLMV-----AYEATAGQSKPGKTELLLPAA 228
                YI WLA +D++A+ A W ++L G+  P ++     A E  AG   P +TE+ L A 
Sbjct: 185  PYRDYIGWLAGRDQAASRALWTEHLAGIDAPTLLTPALSAVEPAAGL--PRRTEVALDAG 242

Query: 229  DTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLF 288
             + RL + A   G+T+NT V  AWA +LS  TDRRDV FG  VSGRP +L GVETMVGLF
Sbjct: 243  ASRRLTETARSRGVTVNTLVQMAWAAMLSVFTDRRDVTFGMTVSGRPGELAGVETMVGLF 302

Query: 289  INAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENA 348
            IN VP+   +   + V +QC  +QR ++A+R+ SYL+ SE++   G G +FDSL V+EN 
Sbjct: 303  INTVPLRVRLDPVDTVGSQCLSLQRTAAALREHSYLAHSELRALAGVGEMFDSLLVYENF 362

Query: 349  PIDDAIRPATTPD--GAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAA 406
            P    +      +  GA F+P  +ESL+H+P+T+ +H+                  L   
Sbjct: 363  PPGGLVGGDHRFEAAGATFIPAALESLSHFPVTIAAHMADERLTVLVETLDGALGALTPH 422

Query: 407  EIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQX 466
            ++G+ +L  + +L  + D    D+ + +  +      + A + P   T V   F    + 
Sbjct: 423  DVGQGLLDTVERLIALWDRPLRDVRMLSGDD----PAVPAVTEPPPRTGVHCAFTEAARR 478

Query: 467  XXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXX 526
                       G   TY E+ A A RLA  L   GVG ET VA+ L R            
Sbjct: 479  TPDAVALSWDGGTL-TYREVDAAADRLAAGLTARGVGAETPVAVRLSRGPDYVIAMLAVL 537

Query: 527  XXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISR 586
                  +P+D  +   R+E I+RQ                 TA P +  D  +A      
Sbjct: 538  KAGGMIVPLDPGMAGERIEEILRQ-----------------TAAPVVVDDALSAGVGAPD 580

Query: 587  RSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXX 646
             + A  TV   P Q+AY +FTSG+TG PKGVVGT+ AVL+Y  DHA  V           
Sbjct: 581  GAWAPATV--APGQAAYAVFTSGTTGIPKGVVGTHDAVLAYADDHARHVLRPAATRLGRP 638

Query: 647  XXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMF 706
                HAWS +FDA+WQP+V L +GH +H+      RDA+ LV+ I    IDMIDTTPSMF
Sbjct: 639  LRIAHAWSFTFDAAWQPLVALFEGHSVHIIGDAVQRDAEALVDTIDRYDIDMIDTTPSMF 698

Query: 707  VQLSAAGLLDH-NLSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXX 762
             QL A GL+    L+VLALGGEA+ +G W  +R     + M  +NCYGPTE TVE     
Sbjct: 699  AQLKAFGLMSRVPLAVLALGGEAVGSGAWRFIREECARTSMTAFNCYGPTETTVESVVAA 758

Query: 763  XKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVA 822
              ++ +P IG+       YV D+ LR VPDGV GELYLSGAQLARGY+ R   TA RFVA
Sbjct: 759  IAEHPQPVIGSPTRHARAYVLDAWLRPVPDGVAGELYLSGAQLARGYLDRACETAGRFVA 818

Query: 823  DPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAA 882
            DP   G RMYRTGD+VRR + G   Y+GR+D QVKIRG+RVE GE+ A L+  P V  A 
Sbjct: 819  DPFLAGNRMYRTGDVVRRDATGALQYLGRSDDQVKIRGFRVEPGEVCAVLQTHPAVRAAH 878

Query: 883  VSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKL 942
            V+V R      L  +          + +LR  L+ RLP Y+VP  I  L  LP+ A+GK+
Sbjct: 879  VTVRRHGAGPRLTAYAA-TGGTDVAVAELRHMLSTRLPRYLVPHHIAVLDELPLTAHGKI 937

Query: 943  DGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIV 1001
            D   L         + + G A +  T TE  L E   E L      ++ DL   G+DSIV
Sbjct: 938  DDATL-----ATYDAAAAGPAAAPETPTEAALAEAVAELLGTTAVDVNADLLSLGLDSIV 992

Query: 1002 AISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAV---DSQDAPADADYGAVRPLPMV 1058
            A+S+V  ARR+G+ +  R++L   +IR+L  A+DA      S  A   A    +  LP V
Sbjct: 993  ALSVVQAARRRGVALRARLMLECGSIRELATAVDAEAGIESSSQATEAASSDPIPVLPNV 1052

Query: 1059 SWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTRE 1118
             WLYEYG+ RR   T  + LP GI   ++  +L+ +LDGH+ LR+    T     +    
Sbjct: 1053 HWLYEYGHPRRLAQTEAIPLPDGITADALRTVLRTVLDGHEVLRTRFDRT----AMTLVP 1108

Query: 1119 PAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADP 1178
             A   A+++L+ + +      +LA AVA        ++DP  G +  A+W R     A  
Sbjct: 1109 QAETPADELLSEVAV----SGDLADAVAEHTETAVQRLDPERGRLWSALWLR----PAHG 1160

Query: 1179 ANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASA 1238
              +L++TAH LA+D  SW +++G+L  AW +L+AG  P    E T+YR+W   +  RA  
Sbjct: 1161 PGVLVVTAHVLAIDPASWRVVIGELDTAWHALRAGRTPTPTREHTTYRQWSARVRERAHR 1220

Query: 1239 PQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQG 1298
                D  D+WAA +   DP LG R   P  D    L+++ A    D+T R++ +    Q 
Sbjct: 1221 ---LDTADFWAAQLDGADPELGARRVRPETDRAGDLEVSVAITEPDLTARLIASA---QA 1274

Query: 1299 VRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL--DTDTTNTVGWFTNAFP 1356
            +  LL  A A  V +WRR R Q P    L+ALE HGRAD+ +  D DT +TVG F+  +P
Sbjct: 1275 MPTLLTLAAARTVTAWRRRRGQ-PTPPPLLALETHGRADSAVSADADTGDTVGLFSAIYP 1333

Query: 1357 VRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDA 1414
            VR+   A  V+                        IP +G+D+GLLRY+  D    L   
Sbjct: 1334 VRVDPDAGPVE------------------------IPGEGIDFGLLRYLRADTAERLCAY 1369

Query: 1415 VDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEG 1474
              PQ+  +YLGR D+GG     +++  G  L A+ + PEP+L +R  + +   +    + 
Sbjct: 1370 RQPQLLLNYLGRADVGGAG--TFNVDKG-LLRAVSVLPEPELAVRHEVTVMAAILPQGDA 1426

Query: 1475 TQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
              L   WR    V    D+  L  LWQ  +  +A
Sbjct: 1427 PVLATQWRTLPEVLSADDVAVLQTLWQDALQEVA 1460


>tr|A1UIR4|A1UIR4_MYCSK Tax_Id=189918 SubName: Full=Amino acid
            adenylation domain;[Mycobacterium sp.]
          Length = 1461

 Score =  885 bits (2288), Expect = 0.0
 Identities = 577/1534 (37%), Positives = 803/1534 (52%), Gaps = 107/1534 (6%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAE----DG---VDLYSMQFVVDIDGPVDLELLRRS 55
            AAA  IEDV+ALSPLQ+GL+++  LA+    DG    D Y +    D+ G +D  LLR  
Sbjct: 6    AAANAIEDVMALSPLQQGLYSMTMLADSEHADGDPRPDPYVIAMAADVTGTLDTALLRDC 65

Query: 56   AQAMLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWSE-RVATPAEFDSIARSERRRPFDL 114
            A A+L RHPNLRA F+  D+P+PVQ+VP    LPW   R  T  +   +   ERRRPFDL
Sbjct: 66   ATALLTRHPNLRAGFFRGDLPRPVQVVPARVDLPWQHVRARTAEKAAELEHRERRRPFDL 125

Query: 115  SRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXX 174
             RGPA+R +++ +PG   R ++  AHHI++DGWSL +F  E+L +               
Sbjct: 126  ERGPAIRFLLIELPGPAWR-LVIVAHHIVIDGWSLPLFVGEMLTLYRAGGDPGALGDPPR 184

Query: 175  XXX-YIVWLAKQDRSAALAGWMDYLRGVSEPLMV-----AYEATAGQSKPGKTELLLPAA 228
                YI WLA +D++A+ A W ++L G+  P ++     A E  AG   P +TE+ L A 
Sbjct: 185  PYRDYIGWLAGRDQAASRALWTEHLAGIDAPTLLTPALSAVEPAAGL--PRRTEVALDAG 242

Query: 229  DTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLF 288
             + RL + A   G+T+NT V  AWA +LS  TDRRDV FG  VSGRP +L GVETMVGLF
Sbjct: 243  ASRRLTETARSRGVTVNTLVQMAWAAMLSVFTDRRDVTFGMTVSGRPGELAGVETMVGLF 302

Query: 289  INAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENA 348
            IN VP+   +   + V +QC  +QR ++A+R+ SYL+ SE++   G G +FDSL V+EN 
Sbjct: 303  INTVPLRVRLDPVDTVGSQCLSLQRTAAALREHSYLAHSELRALAGVGEMFDSLLVYENF 362

Query: 349  PIDDAIRPATTPD--GAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAA 406
            P    +      +  GA F+P  +ESL+H+P+T+ +H+                  L   
Sbjct: 363  PPGGLVGGDHRFEAAGATFIPAALESLSHFPVTIAAHMADERLTVLVETLDGALGALTPH 422

Query: 407  EIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQX 466
            ++G+ +L  + +L  + D    D+ + +  +      + A + P   T V   F    + 
Sbjct: 423  DVGQGLLDTVERLIALWDRPLRDVRMLSGDD----PAVPAVTEPPPRTGVHCAFTEAARR 478

Query: 467  XXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXX 526
                       G   TY E+ A A RLA  L   GVG ET VA+ L R            
Sbjct: 479  TPDAVALSWDGGTL-TYREVDAAADRLAAGLTARGVGAETPVAVRLSRGPDYVIAMLAVL 537

Query: 527  XXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISR 586
                  +P+D  +   R+E I+RQ                 TA P +  D  +A      
Sbjct: 538  KAGGMIVPLDPGMAGERIEEILRQ-----------------TAAPVVVDDALSAGVGAPD 580

Query: 587  RSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXX 646
             + A  TV   P Q+AY +FTSG+TG PKGVVGT+ AVL+Y  DHA  V           
Sbjct: 581  GAWAPATV--APGQAAYAVFTSGTTGIPKGVVGTHDAVLAYADDHARHVLRPAATRLGRP 638

Query: 647  XXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMF 706
                HAWS +FDA+WQP+V L +GH +H+      RDA+ LV+ I    IDMIDTTPSMF
Sbjct: 639  LRIAHAWSFTFDAAWQPLVALFEGHSVHIIGDAVQRDAEALVDTIDRYDIDMIDTTPSMF 698

Query: 707  VQLSAAGLLDH-NLSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXX 762
             QL A GL+    L+VLALGGEA+ +G W  +R     + M  +NCYGPTE TVE     
Sbjct: 699  AQLKAFGLMSRVPLAVLALGGEAVGSGAWRFIREECARTSMTAFNCYGPTETTVESVVAA 758

Query: 763  XKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVA 822
              ++ +P IG+       YV D+ LR VPDGV GELYLSGAQLARGY+ R   TA RFVA
Sbjct: 759  IAEHPQPVIGSPTRHARAYVLDAWLRPVPDGVAGELYLSGAQLARGYLDRACETAGRFVA 818

Query: 823  DPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAA 882
            DP   G RMYRTGD+VRR + G   Y+GR+D QVKIRG+RVE GE+ A L+  P V  A 
Sbjct: 819  DPFLAGNRMYRTGDVVRRDATGALQYLGRSDDQVKIRGFRVEPGEVCAVLQTHPAVRAAH 878

Query: 883  VSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKL 942
            V+V R      L  +          + +LR  L+ RLP Y+VP  I  L  LP+ A+GK+
Sbjct: 879  VTVRRHGAGPRLTAYAA-TGGTDVAVAELRHMLSTRLPRYLVPHHIAVLDELPLTAHGKI 937

Query: 943  DGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIV 1001
            D   L         + + G A +  T TE  L E   E L      ++ DL   G+DSIV
Sbjct: 938  DDATL-----ATYDAAAAGPAAAPETPTEAALAEAVAELLGTTAVDVNADLLSLGLDSIV 992

Query: 1002 AISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAV---DSQDAPADADYGAVRPLPMV 1058
            A+S+V  ARR+G+ +  R++L   +IR+L  A+DA      S  A   A    +  LP V
Sbjct: 993  ALSVVQAARRRGVALRARLMLECGSIRELATAVDAEAGIESSSQATEAASSDPIPVLPNV 1052

Query: 1059 SWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTRE 1118
             WLYEYG+ RR   T  + LP GI   ++  +L+ +LDGH+ LR+    T     +    
Sbjct: 1053 HWLYEYGHPRRLAQTEAIPLPDGITADALRTVLRTVLDGHEVLRTRFDRT----AMTLVP 1108

Query: 1119 PAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADP 1178
             A   A+++L+ + +      +LA AVA        ++DP  G +  A+W R     A  
Sbjct: 1109 QAETPADELLSEVAV----SGDLADAVAEHTETAVQRLDPERGRLWSALWLR----PAHG 1160

Query: 1179 ANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASA 1238
              +L++TAH LA+D  SW +++G+L  AW +L+AG  P    E T+YR+W   +  RA  
Sbjct: 1161 PGVLVVTAHVLAIDPASWRVVIGELDTAWHALRAGRTPTPTREHTTYRQWSARVRERAHR 1220

Query: 1239 PQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQG 1298
                D  D+WAA +   DP LG R   P  D    L+++ A    D+T R++ +    Q 
Sbjct: 1221 ---LDTADFWAAQLDGADPELGARRVRPETDRAGDLEVSVAITEPDLTARLIASA---QA 1274

Query: 1299 VRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL--DTDTTNTVGWFTNAFP 1356
            +  LL  A A  V +WRR R Q P    L+ALE HGRAD+ +  D DT +TVG F+  +P
Sbjct: 1275 MPTLLTLAAARTVTAWRRRRGQ-PTPPPLLALETHGRADSAVSADADTGDTVGLFSAIYP 1333

Query: 1357 VRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDA 1414
            VR+   A  V+                        IP +G+D+GLLRY+  D    L   
Sbjct: 1334 VRVDPDAGPVE------------------------IPGEGIDFGLLRYLRADTAERLCAY 1369

Query: 1415 VDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEG 1474
              PQ+  +YLGR D+GG     +++  G  L A+ + PEP+L +R  + +   +    + 
Sbjct: 1370 RQPQLLLNYLGRADVGGAG--TFNVDKG-LLRAVSVLPEPELAVRHEVTVMAAILPQGDA 1426

Query: 1475 TQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
              L   WR    V    D+  L  LWQ  +  +A
Sbjct: 1427 PVLATQWRTLPEVLSADDVAVLQTLWQDALQEVA 1460


>tr|A4T2D1|A4T2D1_MYCGI Tax_Id=350054 SubName: Full=Amino acid
            adenylation domain;[Mycobacterium gilvum]
          Length = 1459

 Score =  882 bits (2279), Expect = 0.0
 Identities = 575/1523 (37%), Positives = 795/1523 (52%), Gaps = 108/1523 (7%)

Query: 8    IEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLR 67
            I DV+ALSPLQ+GL++L  ++ DG D Y +    DI G +D+ LL   A A+L RHPNLR
Sbjct: 9    IADVMALSPLQQGLYSLTAMS-DGDDPYLIGMSADITGALDVSLLHDCAAAVLARHPNLR 67

Query: 68   AAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSV 127
            A F+  D+ +PVQ++P    + W        E + + R ER R FDL RGPA+R ++L  
Sbjct: 68   AGFFQGDLKRPVQVIPEKVEVLWRHVRCDGTEVEPLEREERARRFDLGRGPAMRFLLLET 127

Query: 128  PGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YIVWLAKQD 186
             G+ + R + TAHHI++DGWSL++  +ELLA+                   YI WLA +D
Sbjct: 128  -GQQRWRFVITAHHIVIDGWSLSLLVSELLALYRAAGNTSALPDAPRPYRDYIGWLAARD 186

Query: 187  RSAALAGWMDYLRGVSEPLMVAYE---ATAGQSKPGKTELLLPAADTARLRQWAGRHGLT 243
            +  A + W  +L  +  P ++A     AT G   PG  EL    + T  +   A   G+T
Sbjct: 187  QDHARSLWRAHLADLDGPTLLAPALGAATIGDGLPGMVELTADPSITEAVVDAARARGVT 246

Query: 244  LNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEA 303
            +N+ V  AWA+ LS LTDR D+ FG  VSGRPD L GVE+M+GLF+N VP+   +     
Sbjct: 247  VNSLVQLAWALTLSSLTDRDDITFGVTVSGRPDDLAGVESMIGLFVNTVPLRVRLDPALT 306

Query: 304  VVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPD-- 361
              AQC  +Q+ ++ +RD SYL  +E++   G G LFD+L V+EN P   A+  A T +  
Sbjct: 307  AGAQCRALQQDAATLRDHSYLGHAELRALAGVGELFDTLLVYENFP-PGAVAGAGTLEAA 365

Query: 362  GAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQLPD 421
            GA F PV ++SL H+P+T+ +HL                  +    +G R+L  + ++ +
Sbjct: 366  GATFTPVALQSLAHFPVTIAAHLTDGRLTVLVEAKDGALGQITPRALGTRLLATVSRIVE 425

Query: 422  IGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRH 481
              D    ++ I          +  A   P+  T V   F                 G   
Sbjct: 426  GWDRPLREISISPDDHPVPVPVSEAAPTPSPSTGVHTRFTETASARLGSVALSWDGGAL- 484

Query: 482  TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPS 541
            TY +L   A RLA  L   GV  ET VA+ L R                  +P+D  +P+
Sbjct: 485  TYRQLDEAADRLAAVLTASGVRTETPVAVRLRRGADYVVAMFAVLKAGGAIVPLDPAMPA 544

Query: 542  ARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPT----VDRR 597
             R+E I+R+A   + + E                      ++++R +A  P      +  
Sbjct: 545  DRIEVILRRAGVTVVVDE----------------------DTVARATAEPPAQYRPAETL 582

Query: 598  PEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSF 657
            P Q+AYV+FTSG+TGEPKGV+GT+ A+L+Y  DH   +               HAWS +F
Sbjct: 583  PGQAAYVVFTSGTTGEPKGVIGTHRALLAYADDHIGAILRPAADRVGRPLRIAHAWSFTF 642

Query: 658  DASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDH 717
            DA+WQP+  LLDGH +H+ D    RDA+ LV+ IA   +DMIDTTPSMF +L   GLL  
Sbjct: 643  DAAWQPLAALLDGHSVHIVDDATQRDAEALVDTIARFGVDMIDTTPSMFARLRDVGLLST 702

Query: 718  -NLSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGT 773
              L+VLALGGEA++ GLW Q+R     + M+ +NCYGPTE TVE        + +PTIG 
Sbjct: 703  VPLAVLALGGEAVDPGLWQQIRQECARTGMSAFNCYGPTETTVEAVVAEIGAHERPTIGR 762

Query: 774  ANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYR 833
              A T  YV DS LR VP G  GELYL+G QL RGY+GRPG TAARFV DP  PG RMYR
Sbjct: 763  PTAPTRAYVLDSWLRPVPSGAAGELYLAGGQLTRGYLGRPGETAARFVPDPFVPGARMYR 822

Query: 834  TGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTS 893
            TGD+VRR   G  A++GR+DTQVKIRG+RVE GE+ A LR  P V  A V+V   +D   
Sbjct: 823  TGDVVRRAVDGTLAFLGRSDTQVKIRGFRVEPGEVAAVLRTHPAVGQAYVAVRPHRDGHR 882

Query: 894  LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAED 953
            L  +V  +  + E    LRA L  RLP Y++P  IV + R+P+ A+GK+D  AL      
Sbjct: 883  LTAYVTGEPQLRE----LRAWLGRRLPRYLMPNAIVAVDRIPLTAHGKIDEPAL-----V 933

Query: 954  ALTSVSGGTAVSASTDTERVLCELFEEQLNAVPHID--DDLFLFGMDSIVAISLVHKARR 1011
            AL   + G A    T TE  L  +  E L  V  ID   D    G+DSIVA+S+V  ARR
Sbjct: 934  ALEPAADGAATRPQTPTEVELAAVLAEVL-GVGEIDVTADFLELGLDSIVALSVVQTARR 992

Query: 1012 QGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRRFT 1071
            +G+ +  +++L   T+R+L AAID A  S    AD   G +  LP   WLYE+G+ RR  
Sbjct: 993  RGVVMRAKLMLDCATVRELAAAIDDA-GSGPPSADEGSGPIALLPNAHWLYEFGDPRRLA 1051

Query: 1072 HTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRI 1131
             T  LRLP GI    I  +LQ ++D H  LR+ L            + AA+   D    +
Sbjct: 1052 STEALRLPRGITGPQIRALLQSVVDAHPVLRTRL------------DRAAMTLVDGGFDL 1099

Query: 1132 TLPE-GSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLA 1190
             L E    DE ++AVA  A    + +DP  G +  A+W RG++     +++LLLTAH LA
Sbjct: 1100 PLTEIEVGDEGSAAVARHAAAALEHLDPQRGPLWGAVWLRGSDDADSTSSVLLLTAHVLA 1159

Query: 1191 VDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAA 1250
            +D VSW I++G+L A W +L  G  P  L E T YR+W  L+  RA +    D   +W  
Sbjct: 1160 MDPVSWQIVIGELDAGWHALAGGRAPAALGEHTGYRQWSNLLRERAES---SDGLQFWLD 1216

Query: 1251 LVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMA 1310
             +  PDPALG R   P  D    +++T      DVT R+L        V ++L+AA    
Sbjct: 1217 QLGGPDPALGARRVRPDTDRAGDVRVTVTVTGADVTARLLAG---PHPVLDVLVAALGRT 1273

Query: 1311 VASWRRVRAQDPAAGVLVALEGHGR--------ADAVLDTDTTNTVGWFTNAFPVRLGAG 1362
            +  WR  R Q P    LVALE HGR        AD     DT++TVG  +  +P+RL   
Sbjct: 1274 ITEWRGRRNQ-PTPPPLVALETHGRAALAEADTADTADTADTSDTVGLLSAIYPLRL--- 1329

Query: 1363 AAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV-DGVAELVDA-VDPQIQ 1420
                     E  P A  +L+         +P  G+DYGLLRY+    +E++ A  +PQI 
Sbjct: 1330 --------HEDSPGATTELI-------AGVPAGGIDYGLLRYLRPDTSEVLKAHPEPQIL 1374

Query: 1421 FSYLGRLDL--GGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLI 1478
             +YLGR DL   G       LL+G     L   PEP+  +R  L +   V    +   L+
Sbjct: 1375 LNYLGRTDLVPSGAIVADRLLLSG-----LSTVPEPNAAVRHELTVVAAVVAHGDEPALV 1429

Query: 1479 GNWRWSDAVFERSDIDHLTGLWQ 1501
              WR    +   +D++ +  +WQ
Sbjct: 1430 AQWRVLPEILSDTDVEEMQTIWQ 1452


>tr|C2AVD1|C2AVD1_TSUPA Tax_Id=521096 SubName: Full=Amino acid
            adenylation enzyme/thioester reductase family
            protein;[Tsukamurella paurometabola DSM 20162]
          Length = 1393

 Score =  839 bits (2168), Expect = 0.0
 Identities = 586/1482 (39%), Positives = 750/1482 (50%), Gaps = 159/1482 (10%)

Query: 2    TAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLD 61
            T+ AP+IEDVLAL+PLQ GL AL  L  DGVD+Y+MQFV+D+DG  D   LR +AQA+LD
Sbjct: 5    TSDAPRIEDVLALTPLQAGLHALAALT-DGVDVYTMQFVIDLDG-ADPARLRSAAQAVLD 62

Query: 62   RHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALR 121
            RHP+LRA+ WDRDVP+PVQ+VP  A LPW ER     E D+  R++   PFDL+ GP LR
Sbjct: 63   RHPHLRASIWDRDVPRPVQVVPDRAVLPWFERRVAADELDAFLRADADAPFDLADGPLLR 122

Query: 122  VVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVW 181
               + V  +   R++FTAHHIL+DGWS+A+FF ELLA+                  Y+ W
Sbjct: 123  ATHVLVD-DGGARLVFTAHHILLDGWSMALFFRELLALYDGIPLPPAPLFRD----YVAW 177

Query: 182  LAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRHG 241
            LA Q     LA W ++L G S   + +     G +  G     L AADTA +  W   +G
Sbjct: 178  LAAQSPEVGLAAWAEHLDGTSPTTLGSGPVRPG-TVSGSVTCTLSAADTATVLDWGRANG 236

Query: 242  LTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGT 301
            LT       AWA VL RLTDR DVVFGTVV+GRP+ LPGVE+MVGLFIN VP    +   
Sbjct: 237  LTPAAVTATAWATVLGRLTDRDDVVFGTVVAGRPEVLPGVESMVGLFINTVPQRVRIDPN 296

Query: 302  EAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPD 361
             A  A C  +Q +++ MR V ++ L++I R+ G GPLFD+LFVFENAP+ DA     T D
Sbjct: 297  AAPAAACAALQAEAARMRSVGHVPLADIARQSG-GPLFDTLFVFENAPLGDATATVRTSD 355

Query: 362  GAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPA----AEIGERMLTVLR 417
            GA F PV M SL HYPL+VV+ +                  L A    AE+GER+L VLR
Sbjct: 356  GAAFRPVTMRSLAHYPLSVVALIDPSDGAPRLTVVIEAVDGLDAVPRPAELGERLLQVLR 415

Query: 418  QLPDIGDGTPDDLDIRTAAELKAHGLLAA---RSAPTFDTTVWEMFERQVQXXXXXXXXX 474
             LP  G  T   L +    +L       A   RS     T +  +F   V          
Sbjct: 416  ALPTTG--TVGALPVERPGDLVPPSASTAGVERSVAGGFTPLPRLFADLVASMPDAPALS 473

Query: 475  XXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLP 534
                V  +Y EL  R    A  L+  G+G    V L+  R ER+             Y+P
Sbjct: 474  TAETVL-SYGELGGRVASAAVALSAAGIGRGDRVGLLADRDERAVIAILAALTVGAAYVP 532

Query: 535  VDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPT- 593
            +   LP  R+ ++  +A+    +   +++Q    A+P +   + A         A  P  
Sbjct: 533  LAPDLPDDRIAAMFERAAVRAVVATTEHAQRTAGALPVVVPPETAG--------AGTPRP 584

Query: 594  VDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAW 653
            VD  P+  AYVIFTSGSTGEPKGV+GT+ A+ +Y ADH  R+Y              H W
Sbjct: 585  VDLGPDDDAYVIFTSGSTGEPKGVLGTHGALAAYRADHVHRMYRPAQERLGRPLRVAHGW 644

Query: 654  SLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAG 713
            SLSFDASWQP++ L  GH + L    E+RDA  ++  +    IDMIDT+PS+F QL+ AG
Sbjct: 645  SLSFDASWQPLLALFAGHHLRLLSDAEIRDAQAMIAVLGDEGIDMIDTSPSLFGQLAEAG 704

Query: 714  LL--DHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTI 771
            L+  D  L VLALGGEAI   LWD+L  L +  VYNCYGPTE TVE           P I
Sbjct: 705  LVDGDERLHVLALGGEAIPPHLWDRLAALPETDVYNCYGPTETTVEAVVGAVTP-GAPRI 763

Query: 772  GTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLR-PGQR 830
            G   AGT  YV D  LR VP G VGELYL G QL RGYVGRP +TAARFVADP    G R
Sbjct: 764  GEPTAGTRAYVLDRRLRSVPAGAVGELYLGGPQLTRGYVGRPDLTAARFVADPFAGGGAR 823

Query: 831  MYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQD 890
            MYRTGDLVR  + G   ++GRAD QVK+RGYR+E+GE+E+AL   PGV  A V V+R+  
Sbjct: 824  MYRTGDLVRLDARGRIVFLGRADDQVKVRGYRIELGEVESALTSAPGVRGAGVVVMRRGG 883

Query: 891  RTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRL 950
              +LVGFV        D   +RA     LP YMVPARI  L RLP+  NGK+DG AL   
Sbjct: 884  SATLVGFVAGS----ADAPSVRAAAARLLPGYMVPARIDVLDRLPLTRNGKVDGAALTAR 939

Query: 951  AEDALTSVSGGTAVSASTDTERVLCELFEE-QLNAVPHIDDDLFLFGMDSIVAISLVHKA 1009
            AE  L +   G  V  ST TE  +  ++EE    A   +  DLF  G+DSI+AI+ V + 
Sbjct: 940  AEALLAAAEAG--VPPSTPTEHAVAAVWEEIWPGAGTDVHADLFDLGLDSILAIAAVGRL 997

Query: 1010 RRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAV--RPLPMVSWLYEYGNY 1067
            RR GL V P  ++   TI  L AA+DA    Q+AP+D D GAV   PLP+V      G Y
Sbjct: 998  RRAGLPVSPATLMANPTIATLAAALDA----QEAPSDVDSGAVDLTPLPLVRRTLLGGGY 1053

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDV 1127
             R+    L  +P+G+    +  +L  +L  H  LR+ L+    G RL+   P  V A  +
Sbjct: 1054 ARYAQAGLFAVPAGVALDEVGRVLDAVLAVHPALRARLS----GGRLLADGP-PVSAAGL 1108

Query: 1128 LTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAH 1187
            L  +    G+D    +A+A   R     +D  AG M+ A   R  +H  D   +L++  H
Sbjct: 1109 LAEL----GTD---PAAIAGTVR----SLDADAGRMLAAGVLRRPDHDHD---LLVVAIH 1154

Query: 1188 HLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDY 1247
            HL  D VSW I+  D+A                         E     A   +V     Y
Sbjct: 1155 HLLADGVSWQILCEDIA-------------------------ETALGGAPLTEVSTAAQY 1189

Query: 1248 WAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAAT 1307
             + L  +    +  R      D  +  Q     +    + R+ G   RD           
Sbjct: 1190 ASRLADDGPACVDTRL--SPADVAAAAQTLGFELAATASARLTG---RD---------VE 1235

Query: 1308 AMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVD 1367
            A+   + RR  A  P     +AL  HGR DA   TDT+ TVGWFT   P           
Sbjct: 1236 AVLADAVRRACALLPDGAPALALTRHGRDDARHGTDTSRTVGWFTTHVPA---------- 1285

Query: 1368 IEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRL 1427
                                        G D G  R+                 +YLGR 
Sbjct: 1286 ----------------------------GPDEGGARWA--------------AVNYLGRR 1303

Query: 1428 DLGGVADQPWSLLTGPYLDAL-PIDPEPDLPLRFALN-LSVF 1467
            DL      PW  +  P L AL P  PEP LPL F L  L+VF
Sbjct: 1304 DL--APSGPWLPVLDPGLTALIPAQPEPALPLLFPLEVLAVF 1343


>tr|Q73XY7|Q73XY7_MYCPA Tax_Id=1770 (mbtF)SubName:
            Full=MbtF;[Mycobacterium paratuberculosis]
          Length = 1412

 Score =  830 bits (2145), Expect = 0.0
 Identities = 519/1262 (41%), Positives = 689/1262 (54%), Gaps = 63/1262 (4%)

Query: 2    TAAAPQIEDVLALSPLQEGLFALHQLAE--DGV---DLYSMQFVVDIDGPVDLELLRRSA 56
            T  AP IEDV+ALSPLQEGL++L  LAE  DG    D Y +    DI G +D+ LLR  A
Sbjct: 6    TDVAPDIEDVMALSPLQEGLYSLTTLAEFADGQPADDPYVIGMAADITGTLDVALLRDCA 65

Query: 57   QAMLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSR 116
            + ML RHPNLRA+F+ R VP+PVQIVP    LPW    A+PAE  ++  +ERRRPFDL R
Sbjct: 66   EKMLVRHPNLRASFFSRGVPRPVQIVPSRVELPWRSVTASPAEVPTLETAERRRPFDLER 125

Query: 117  GPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXX 176
            GPA+R +++ +P +   R++ TAHHI++DGWSL VF  EL+ +                 
Sbjct: 126  GPAIRFLLIELP-DAHWRLVLTAHHIVIDGWSLPVFVNELMTLYRAGGDPSALPAAPRPY 184

Query: 177  X-YIVWLAKQDRSAALAGWMDYLRGVSEPLMVA-----YEATAGQ--SKPGKTELLLPAA 228
              YI WLA +D  A+   W ++L G+  P ++A      EAT GQ  + P  TEL +PA 
Sbjct: 185  RDYIGWLAGRDLQASQRVWREHLAGLPGPTLLAASLGSVEATEGQRTALPRTTELRMPAE 244

Query: 229  DTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLF 288
             TARL       G+T+NT +  AWA+VLSRLTD RDVVFG  VSGRP +L GVETMVGLF
Sbjct: 245  ATARLAAETRSRGITVNTLMQMAWALVLSRLTDTRDVVFGVTVSGRPPELTGVETMVGLF 304

Query: 289  INAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENA 348
            IN VP+   +     V  QC  VQR ++ +R+ SYL  ++++   G G +FD+L V+EN 
Sbjct: 305  INTVPMRVRLDPAATVGEQCRAVQRDAALLREHSYLGHAQLRALGGIGEMFDTLLVYENF 364

Query: 349  PIDDAIRPAT-TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAE 407
            P+D        +  GA F P  +++L+H+P+ V +H+                  +PA  
Sbjct: 365  PMDGLTAGGELSAGGATFRPSALQTLSHFPIAVAAHMEGGELVVLIEVVDGALGVIPADA 424

Query: 408  IGERMLTVLRQLPDIGDGTPDDLDIR---TAAELKAHGLLAARSAPTFDTTVWEMFERQV 464
            +G R+LT   +L    +     + +     AA L+A G +A  S         ++  +  
Sbjct: 425  VGRRLLTTAERLLRHWERPLRAVSVLFDDEAAPLRAAGPIAPPSPKCLPARFADVVAQTP 484

Query: 465  QXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXX 524
                             TY +L     RLA +L   GV PET VA+ L R  R       
Sbjct: 485  DAPAVSWAQGSL-----TYRDLDEATNRLAAQLVALGVEPETPVAIKLFRGPRYVVAMLA 539

Query: 525  XXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESI 584
                    +P++  +P+ RV SI+RQ+  ++ + E    +L+               E+ 
Sbjct: 540  VLKAGGMCVPMEPGMPAPRVNSILRQSGASIVLDEERIDELL---------------EAA 584

Query: 585  SRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXX 644
              R       D  P Q+AYV+FTSG+TGEPKGV+GT+ AV +Y  DH +RV         
Sbjct: 585  RSRHGGFEPPDIPPAQAAYVVFTSGTTGEPKGVIGTHGAVGAYADDHLDRVLRPAAAALG 644

Query: 645  XXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPS 704
                  HAWS +FDA+WQP+V LLDGH +H+ D     DA+ LV  IA   +DMIDTTPS
Sbjct: 645  RPLRIAHAWSFAFDAAWQPLVALLDGHGVHVVDEATQTDAEALVALIAEHGVDMIDTTPS 704

Query: 705  MFVQLSAAGLLDHN-LSVLALGGEAINTGLWDQLRGL---SQMAVYNCYGPTEMTVEXXX 760
            MF QL A GLL    L+VLALGGEA+ +  W ++R     + M+ YNCYGPTE TVE   
Sbjct: 705  MFAQLQAFGLLSEAPLTVLALGGEALGSAAWARIRNACNTTTMSAYNCYGPTETTVEAVV 764

Query: 761  XXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARF 820
                ++ +P+IG     T GYV DS LR VP G  GELYL GAQLARGY+GR G TA+RF
Sbjct: 765  AAIAEHAEPSIGRPTRHTRGYVLDSELRPVPCGATGELYLGGAQLARGYLGRAGETASRF 824

Query: 821  VADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHD 880
            VADP    +RMYRTGDLVRRL  G   YVGRAD QVKIRG+RVE GEI AAL   P V  
Sbjct: 825  VADPFAASERMYRTGDLVRRLPDGSLQYVGRADAQVKIRGHRVEPGEIAAALESHPAVRH 884

Query: 881  AAVSVLRQQDRTSLVGFVVWQDNMHE--DLIKLRAGLTERLPSYMVPARIVTLPRLPVNA 938
            A V V  +     L G+V       +     +LR  L+ RLP YMVP RI+ +  +P+  
Sbjct: 885  AGVLVRHRDGAPRLTGYVATHQAAADTPSPAELRGMLSARLPRYMVPQRIIMVDEIPLTP 944

Query: 939  NGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPHID--DDLFLFG 996
            NGKLD  AL   A D   +V G  A    T TE  L EL  E L   P +D   D    G
Sbjct: 945  NGKLDETAL--AAVDNAEAVDG--AAPPQTGTESALAELIAELLGQ-PRVDVTADFLALG 999

Query: 997  MDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLP 1056
            +DSI+A+S+V  AR +G+ +  R+VL  T+IR+L  AIDA         D   G +  LP
Sbjct: 1000 LDSIMALSVVQAARARGIALRARLVLDCTSIRELAEAIDAESTPAAGEVDDGTGPMPLLP 1059

Query: 1057 MVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVT 1116
               WLYE+G  RR   T  +R+P  + R  +E  L  ++ GH+ LRS +         +T
Sbjct: 1060 NGRWLYEHGQPRRLAQTEAIRVPQTLRRDQLETALAGIVGGHEVLRSRVDRA-----TMT 1114

Query: 1117 REPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRA 1176
              P    A D+   +       D  A+   HAAR + D++DP  G ++RA+W R     A
Sbjct: 1115 LVPGP--APDIGRELEEVAVVGDLRAAVADHAARAI-DRLDPERGVLLRAVWLR----PA 1167

Query: 1177 DPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRA 1236
                +LLLTAH +A+D  SW ++LG+L AA  +   G  P  + E TSYRRW   +  RA
Sbjct: 1168 GGDGVLLLTAHVIALDPASWRVVLGELGAALTAAATGHSPAAVREHTSYRRWAHALTARA 1227

Query: 1237 SA 1238
             A
Sbjct: 1228 PA 1229



 Score = 55.5 bits (132), Expect = 6e-05
 Identities = 72/270 (26%), Positives = 110/270 (40%), Gaps = 33/270 (12%)

Query: 1182 LLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEF-TSYRRWCELMWHRASAPQ 1240
            L+LTAHH+ +D  S  + + +L   +R   AG  P  LP     YR +   +  R     
Sbjct: 143  LVLTAHHIVIDGWSLPVFVNELMTLYR---AGGDPSALPAAPRPYRDYIGWLAGRDLQAS 199

Query: 1241 VQDQRDYWAALVREPDPALGLRYPDPTRDTWSTL-QLTRAAIPVDVTERVLGAVRRDQGV 1299
             +  R++ A L      A  L   + T    + L + T   +P + T R L A  R +G+
Sbjct: 200  QRVWREHLAGLPGPTLLAASLGSVEATEGQRTALPRTTELRMPAEATAR-LAAETRSRGI 258

Query: 1300 RELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRL 1359
                L   A A+   R    +D   GV V+    GR   +   +T   VG F N  P+R+
Sbjct: 259  TVNTLMQMAWALVLSRLTDTRDVVFGVTVS----GRPPELTGVET--MVGLFINTVPMRV 312

Query: 1360 GAGAAAVDIEQ---AERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAV- 1415
                AA   EQ    +RD    ++  HS + H +           LR + G+ E+ D + 
Sbjct: 313  RLDPAATVGEQCRAVQRDAALLRE--HSYLGHAQ-----------LRALGGIGEMFDTLL 359

Query: 1416 ----DPQIQFSYLGRLDLGGVADQPWSLLT 1441
                 P    +  G L  GG   +P +L T
Sbjct: 360  VYENFPMDGLTAGGELSAGGATFRPSALQT 389


>tr|C1AT72|C1AT72_RHOOB Tax_Id=632772 SubName: Full=Putative
            non-ribosomal peptide synthetase;[Rhodococcus opacus]
          Length = 3081

 Score =  791 bits (2042), Expect = 0.0
 Identities = 561/1551 (36%), Positives = 781/1551 (50%), Gaps = 90/1551 (5%)

Query: 8    IEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLR 67
            +EDV+ L+PLQ+G+F L  L   GVD+Y+M+ V+DI+G +D  +LRRSA+A++ RH NLR
Sbjct: 1566 VEDVVPLTPLQQGMFFLSGLDTTGVDVYTMRTVLDIEGALDTAVLRRSAEALVARHANLR 1625

Query: 68   AAFWDRDVPKPVQIVPVHAALPWSERVA-------TPAEFDSIARSERRRPFDLSRGPAL 120
              F      +P+ +V   A LPW E            AE+ ++   +R   FD +  P L
Sbjct: 1626 TGFRISAAGEPIGVVLGDAILPWRETDLHRLPSGDAAAEWSALLDDDRNLRFDPNTAPLL 1685

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIV 180
            R  ++ V GE++ R++FTAHH+L+DGWS  +   EL+ +                  Y+ 
Sbjct: 1686 RFTLVRV-GESRYRLVFTAHHLLLDGWSTPLLIQELIQLYGAAADPSVLRPVRPYSDYLT 1744

Query: 181  WLAKQDRSAALAGWMDYLRGVSEP-LMVAYEATAGQSKPGKTELLLPAADTARLRQWAGR 239
            WL +QD    LA W + L GV EP L+ A  ++     PG+  + +P   +  L   +  
Sbjct: 1745 WLKQQDTERGLAVWTEALAGVEEPTLLAAAGSSLDPQIPGEISVSVPEGLSGGLLDLSRS 1804

Query: 240  HGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVS 299
             G+T+NTAV  AW ++L  + +R DVVFG +VSGR   + G+ETMVGLFIN VPV   V 
Sbjct: 1805 LGITVNTAVQAAWGLLLGSVLNRPDVVFGAIVSGRVPDVAGIETMVGLFINTVPVRVGVR 1864

Query: 300  GTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPID-DAIRPAT 358
              E V     +VQ + + + D  Y+ LS+IQR  G G +FDSL VFE+ P+D +A+  A 
Sbjct: 1865 PQETVDEFLRRVQGEQNKVMDHQYVGLSDIQRSVGIGEMFDSLIVFESYPVDTEALEAAQ 1924

Query: 359  TPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQ 418
               G +    E +  T++PL +V+ L                    A  +GER++ +L Q
Sbjct: 1925 RAGGIRVSHSEGQDATNFPLVLVAGLEGELDLMLEYQPALFTND-EATLLGERLVRILEQ 1983

Query: 419  LPDIGDGT-----PDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXX 473
            L  + D T      D L     A++     +   +A +  +TV E+F  QV         
Sbjct: 1984 L--VADRTLPTARIDVLSQSERAQVLGEWAVTESAAASGFSTVAELFAAQVDRTPDTTAV 2041

Query: 474  XXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYL 533
                    T+AEL  R  RLA  L + GVGPE+ V L LPR+                Y+
Sbjct: 2042 VCGDDTL-TFAELGVRVARLARALIDAGVGPESKVGLALPRTTDMVVAIFAVVSAGGAYV 2100

Query: 534  PVDVTLPSARVESIVRQASPALAITEADYSQLVG-----TAVPTLALDDPAAVESISRRS 588
            P+D + P+ R+  +V  A P + ++ A  +  +G     +    L LDDPA    +  R 
Sbjct: 2101 PMDPSYPADRLAHMVSDARPTVVVSTATVAGNLGEILSDSGASLLVLDDPA----VQGRL 2156

Query: 589  AAAP-----TVDRRP----EQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVY-XX 638
            AA P       DRR       + YVI+TSGSTG PKGV  T+A +L+ F  H + +Y   
Sbjct: 2157 AALPGTPVTDTDRRAPLRGANTVYVIYTSGSTGVPKGVSITHANLLNLFHSHRQSLYLPT 2216

Query: 639  XXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDM 698
                        HAWS SFDASWQP + LLDGH +H+FD E MRD D +V      ++D 
Sbjct: 2217 AAASGRDSIGVGHAWSFSFDASWQPTLWLLDGHTVHVFDEETMRDPDLMVRQTREHRLDF 2276

Query: 699  IDTTPSMFVQLSAAGLLDHN--LSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV 756
            ++ TPS   ++ AAGL +H    + +  GGEA+N  LW  LR +++   +N YGPTE TV
Sbjct: 2277 LEVTPSFLDRMVAAGLYEHEHVPATVGFGGEAVNPALWRTLREIAEGRAFNLYGPTECTV 2336

Query: 757  EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMT 816
            +       D  +P +G A  G   YV D  LR VP GV GELYL+G  +ARGY+GRP +T
Sbjct: 2337 DALIAKAADAEEPLLGRAVHGGTAYVLDRLLRPVPAGVAGELYLAGNGVARGYLGRPDLT 2396

Query: 817  AARFVADPL-RPGQRMYRTGDLVRRLSHG-GYAYVGRADTQVKIRGYRVEVGEIEAALRG 874
            + RFV DP    G+RMYRTGD+VR  S G G  YVGRAD QVKIRG+RVE+GE+E+AL  
Sbjct: 2397 SGRFVPDPFGGAGERMYRTGDVVRWASTGSGLEYVGRADDQVKIRGFRVELGEVESALAA 2456

Query: 875  QPGVHDAAVSVLRQQDR--TSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLP 932
              GV DA V +    DR    LVG+V     +  D   +R+ + ERLP YMVPA IV + 
Sbjct: 2457 VAGVRDAVV-IAHTDDRGVRRLVGYVTVDGAL--DPAVVRSVVAERLPDYMVPAAIVVVG 2513

Query: 933  RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDD 991
              PVNANGK+D  AL      AL   SG        DTE  LC +F + L      ++DD
Sbjct: 2514 AFPVNANGKVDRKALPEPDFGALVG-SG----EPRNDTEATLCAVFADVLGLDRVGVEDD 2568

Query: 992  LFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAA------VDSQDAPA 1045
             F  G DSIV+I LV + R  GL+V  R V    T   L A    A      V + +A A
Sbjct: 2569 FFALGGDSIVSIQLVSRLRAAGLQVSARQVFELRTAAGLAALAGIAEVPGVTVGATEADA 2628

Query: 1046 DADYGAVRPLPMVSW--LYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRS 1103
              D     PL  + W  L   G+  RF+   LL  P G+D   +E  ++ LL  H  LRS
Sbjct: 2629 VGDV----PLTPIVWEPLEWGGDISRFSQARLLVAPLGLDVPVLERAVEGLLRTHHLLRS 2684

Query: 1104 ILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAM 1163
                T   P  V  E     A  ++ R+ +     D   +            +DP+AG M
Sbjct: 2685 RFVVTGGEPDWVVPETVGAVA-PLVRRVDVSALPADGWQALFTTERERAYAALDPAAGVM 2743

Query: 1164 VRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFT 1223
            ++ ++F   +        + +  HHL VD VSW I++ DLA A   + AG    +    T
Sbjct: 2744 LQVVFF---DFGPGKRGRVFVAVHHLVVDGVSWRILVPDLALAVTQVTAGEQVSLHSAGT 2800

Query: 1224 SYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPV 1283
            S+R W   +   A+  ++     +W       +P LG+R  DP  DT S+       +P 
Sbjct: 2801 SFRAWAAGLAEAATTERITAGWSHWQHAALADEPQLGVRPLDPALDTVSSTCSISVRVPT 2860

Query: 1284 DVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL-DT 1342
            DVTERVL A      V ++LLAA A+AVAS R          V V LEGHGR + V+   
Sbjct: 2861 DVTERVLAA----GSVNDVLLAALALAVASER------GGDVVRVDLEGHGREEQVVPGA 2910

Query: 1343 DTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLL 1402
            D + T+GWFT+ FPV L  G   +D+  A     AA D +  V   L ++P++G+ +GLL
Sbjct: 2911 DISRTIGWFTSMFPVALDLG--GIDVADAIAGGPAAADALDEVSRSLRSVPDNGIGFGLL 2968

Query: 1403 RYVDGVAELVDAVD----PQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPL 1458
            R ++   E  D  D    P + F+YLGR+ LG  A   WS    P   AL    +P  PL
Sbjct: 2969 RRLN--PEFADRFDGYRAPAVVFNYLGRMTLGESAGSAWS--GAPEGVALGGSVDPATPL 3024

Query: 1459 RFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
               L +      T +G  L   +  +D V        L   W + + AL A
Sbjct: 3025 DHVLQVDAITEDTDDGPVLDCEFAAADGVLTADSTRALADRWVQAVTALVA 3075



 Score =  729 bits (1882), Expect = 0.0
 Identities = 545/1559 (34%), Positives = 775/1559 (49%), Gaps = 98/1559 (6%)

Query: 8    IEDVLALSPLQEGLFALHQLA--EDG-------VDLYSMQFVVDIDGPVDLELLRRSAQA 58
            +ED++ LSPLQ+GL  L  +A  +DG        D+Y++Q V+ +DGPVD + +R SAQA
Sbjct: 7    LEDIVPLSPLQQGLLFLSTVAAPDDGDDTGSAEPDVYTVQSVIRLDGPVDDDRMRASAQA 66

Query: 59   MLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSER---------R 109
            +LDRH  +R  F  R   +   +V     +PW  R     E+D   +  R         R
Sbjct: 67   LLDRHAVMRTCFRPRKDGRHAGLVVRAVEVPW--RTVDLTEYDPAEQERRIADLLVDDLR 124

Query: 110  RPFDLSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXX 169
              FDL++ P +R +++ +  ++ R ++FTAHHI+VDGWS  +   ELL +          
Sbjct: 125  TWFDLAQPPLVRWLLVRLAPDSVR-LLFTAHHIVVDGWSTPILVRELLEIYAAGGTANGL 183

Query: 170  XXXXXXXXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKT-ELLLPAA 228
                    Y+ WL +QD   A A W + L G+ EP ++    +   +   +  EL +PA 
Sbjct: 184  PAVRKYSDYLAWLGRQDHDRARALWQETLSGLDEPCLLTPPGSTRVTTDSRALELDVPAG 243

Query: 229  DTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLF 288
                L + A   G+TLNT +   WA++LS L  R DVVFG  VSGRP +L GVE+MVGLF
Sbjct: 244  LGDSLAEVARTSGVTLNTVLQTGWALLLSGLLGRGDVVFGATVSGRPPELAGVESMVGLF 303

Query: 289  INAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENA 348
            IN VPV   +   E V     +VQ+  +   D  Y+ LS+IQR+ G G LFD+L +FE+ 
Sbjct: 304  INTVPVRVRLDAAETVRDLLQRVQQGQARTLDHQYVGLSDIQRDTGLGELFDTLTIFESY 363

Query: 349  PID-DAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAE 407
            P+D DA+  A    G     V+    T+YPL + + +                    A  
Sbjct: 364  PVDRDALERAQRDGGVSIAGVDGHDGTNYPLVLTAGVAETLKLIIDYRPTLLSD-ADAER 422

Query: 408  IGERMLTVLRQLPDIGDGTPDDLDIRTAAE---LKAHGLLAARSAPTFDTTVWEMFERQV 464
            IG R+L +L  L   G      +   TA+E   + A   +A  +  +   TV ++   Q+
Sbjct: 423  IGARLLHILDTLAAGGSARAASVAALTASERELVLAEWAVAKPAVESGFPTVADLLSEQM 482

Query: 465  QXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXX 524
                             T+AEL + + RLA  L   GVGPE+ V L LPRS  +      
Sbjct: 483  S-RTPHGTAVVYGDTSLTFAELASDSARLARLLIAAGVGPESRVGLALPRSAETVVAIAA 541

Query: 525  XXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQ---LVGTAVPTLALDDPA-A 580
                   YLP+D + P+ R+  +V  ++P + +T    SQ    V   V  + LDDPA A
Sbjct: 542  VLTAGGAYLPLDPSYPADRLAHMVSDSAPTVVVTTEAVSQKFAAVLDGVSVVKLDDPAVA 601

Query: 581  VESISRRSAAAPTVDRR----PEQSAYVIFTSGSTGEPKGVVGTNAAVLS-YFADHAERV 635
             E  +  +      +RR     + +AYVI+TSGSTG PKGV  ++A +L  + A  A  +
Sbjct: 602  AELAALPTGPVTDAERRTRLHTDNAAYVIYTSGSTGLPKGVTVSHANLLDLHGAQRATTM 661

Query: 636  Y-XXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIG 694
                              +  +FD+S   +  L +GH +H+   E   D   +VE +   
Sbjct: 662  RPAAGRTPADDPWRVLLTYPFAFDSSVAALTWLFEGHALHILPEERRSDTAFVVEYVRAN 721

Query: 695  QIDMIDTTPSMFVQLSAAGLLD----HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYG 750
            +ID +D+ P +  QL   GLLD    H  + + +GGEA+   LW++L G   +  YN YG
Sbjct: 722  RIDYVDSVPVLMNQLLDEGLLDAGASHRPAKVTVGGEAVTPALWERLAGTGGVEAYNFYG 781

Query: 751  PTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYV 810
            PTE TV+             IG    GT  YV D  LR VP GV GELY++GA +ARGY+
Sbjct: 782  PTECTVDAAFARISG-GTVAIGEPTPGTSVYVLDGWLRPVPPGVAGELYVAGAGVARGYL 840

Query: 811  GRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIE 869
            GRP +T+ RF+ DP   PGQRMYRTGD+VR    G   YVGR D QVKIRG+RVE+GE+E
Sbjct: 841  GRPDLTSGRFLPDPFSAPGQRMYRTGDVVRWTGSGVLEYVGRGDDQVKIRGFRVELGEVE 900

Query: 870  AALRGQPGVHDAAV-SVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARI 928
             AL    GV DA V +    +D   LVG+V    +     + +R+   ERLP YMVPA +
Sbjct: 901  TALAAVEGVRDAVVLAHTDDRDVRRLVGYVTVDGS--PSAVAVRSAAGERLPDYMVPAVV 958

Query: 929  VTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPH 987
            + L  LPV ANGK+D  AL      AL   SG       T TE  LC +F E L      
Sbjct: 959  IVLDTLPVTANGKVDRKALPEPDFGALAG-SG----EPRTATEAALCAVFAEVLGLDRVG 1013

Query: 988  IDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDA-----AVDSQD 1042
            ++DD F  G DSIV+I LV +ARR  +RV  R V    T  +L AA+DA       D+ +
Sbjct: 1014 VEDDFFALGGDSIVSIQLVSRARRDDIRVTARQVFELRTAERLAAAVDAESGAEIPDTVE 1073

Query: 1043 APADADYGAVRPLPMVSW--LYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDT 1100
             PA+ D     P+  + W  L + G+  RF    LL  P G+    +   ++ LL  H  
Sbjct: 1074 VPAEGDV----PVTPIVWEALRQGGDLDRFAQARLLLAPVGLTEPVLAEAVRALLATHPL 1129

Query: 1101 LRS---ILTETPEG--PRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARV-VTD 1154
            LRS   +   TP+   P  V   P  VR      R+T+   SD +    V  A R     
Sbjct: 1130 LRSRFAVTDGTPQWTVPNSVDEGPNPVR------RVTV---SDADAWQTVFEAERERAYA 1180

Query: 1155 QIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGT 1214
             +DP+AG M++ ++F   +   D A  +    HHL VD VSW I++ DLA+A   + AG 
Sbjct: 1181 ALDPAAGVMLQVVFF---DFGPDRAGRVFAAVHHLVVDGVSWRILVPDLASAVEQITAGR 1237

Query: 1215 PPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTL 1274
            P  + P  TS+R W   +   A++ +V      W   V   +PALG R  D TRDT ++ 
Sbjct: 1238 PVALEPAGTSFRGWATGLVEAAASDRVTAGWPVWEVAVNADEPALGHRPLDRTRDTVASA 1297

Query: 1275 QLTRAAIPVDVTERVLGAVRR--DQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEG 1332
            +     +PVDVT  VL +V      GV ++LL A A+AV S   VR  D    V V LEG
Sbjct: 1298 RSVEVHVPVDVTAHVLTSVPAAFRAGVNDVLLTALAVAVVS---VRGGDV---VRVDLEG 1351

Query: 1333 HGRADAVL-DTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEA 1391
            HGR + V+   D + TVGWFT+ +PV L    +++D         AA   +  V   L +
Sbjct: 1352 HGREEQVVPGADISRTVGWFTSLYPVAL--DLSSLDPADVLTGGPAAGLALRRVKESLRS 1409

Query: 1392 IPNDGLDYGLLRYV--DGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALP 1449
            +P++G+ +GLL  +  +  A       P + F+YLGR+ LG   D  WS    P  DAL 
Sbjct: 1410 VPDNGIGFGLLSRLNPEYTARFDGYRPPSVMFNYLGRMTLGENTDGAWS--GAPEADALG 1467

Query: 1450 IDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
               +P  PL   L+++     TA+G  L   +  +D + +  D   +  +W   + ALA
Sbjct: 1468 GTVDPGTPLDHVLDVNAITEDTADGPVLSCVFTAAD-MLDAEDTSRIAEVWVEALTALA 1525


>tr|Q6ZZJ4|Q6ZZJ4_ACTTI Tax_Id=1867 (teiC)SubName: Full=Peptide
            synthetase, module 4-6;[Actinoplanes teichomyceticus]
          Length = 4067

 Score =  726 bits (1875), Expect = 0.0
 Identities = 532/1501 (35%), Positives = 749/1501 (49%), Gaps = 96/1501 (6%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            +IED+  LSPLQEGL       ++G D+Y   +++D+DGPVD   LR + +A+L RH  L
Sbjct: 5    RIEDIWPLSPLQEGLLFHTVYDDEGPDVYVGHWILDLDGPVDAARLRAAWEALLARHAAL 64

Query: 67   RAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDS-------IARSERRRPFDLSRGPA 119
            RA F  R   + VQ+V     LPW  RV   A  D        +A  +R RPFD+++ P 
Sbjct: 65   RACFRQRRTGETVQVVAGRVELPW--RVVDLAHLDDPEHAVRELADEDRLRPFDVAKPPL 122

Query: 120  LRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYI 179
            LR+ ++ +  + + R++ T HH ++DGWSL + F EL A+                  Y+
Sbjct: 123  LRLTLIRL-ADDRHRLVVTCHHAVMDGWSLPIVFDELTALYAAGDGPAQLPAVTPYREYL 181

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSK--PGKTELLLPAADTARLRQWA 237
             WL++QD+ +ALA W   LRG  EP +VA  A  G++   P   E+ L    T  L + A
Sbjct: 182  AWLSRQDKPSALAAWAAELRGAQEPTLVA-PADPGRAPGMPESVEVQLSPELTRSLAELA 240

Query: 238  GRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHY 297
               GLTLNT +  AWA+VL+RLT R DVVFG  VS RP  LPGVE MVGLF+N VPV   
Sbjct: 241  RGRGLTLNTVIQGAWALVLARLTGRTDVVFGATVSARPAHLPGVEAMVGLFLNTVPVRVR 300

Query: 298  VSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAP--IDDAIR 355
            + G+  VV    ++Q++ SA+    ++ L++IQ+  G G +FD+L VFEN P  +DD+  
Sbjct: 301  LRGSAPVVEMLAELQKRQSALIPEQFVGLADIQKAAGPGAVFDTLLVFENFPRELDDS-- 358

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
               + D       +     HYPLT+V+ +                    AA I ER   V
Sbjct: 359  --RSADAFGIRVHQGREAAHYPLTLVA-VPGESMLFKLDYLTELFDAATAASILERFTRV 415

Query: 416  LRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXX 475
            LR+L D G+ T   +D+ +AAE        A      D    ++F RQV           
Sbjct: 416  LRRLTDAGELTVAAIDVTSAAERDRVARWGAAVGARPDRLALDLFARQVAQRPDEVAVAD 475

Query: 476  XXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPV 535
               V  ++ EL  RA RLAG L+  GV     VA+V+ RS                ++PV
Sbjct: 476  GDRVM-SFGELAERADRLAGHLSARGVRRGDRVAVVMERSGELIATLLAVWRAGAAFVPV 534

Query: 536  DVTLPSARVESIVRQASPALAITEADY-SQLVGTAVPTLALDDPAAVESISRRSAAAPTV 594
            D   P+ RV+ ++  A P  A+  A + + ++   +  + +DDP    ++    A  P V
Sbjct: 535  DPAYPAERVKFLLTDAEPVAAVCTAAFRAAVLDGGLEAIVVDDPGTWPAV----APCPPV 590

Query: 595  DRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWS 654
               P+  AYV++TSGSTG PKGV  ++  V +   D   R                HA+ 
Sbjct: 591  PTGPDDLAYVMYTSGSTGTPKGVAVSHGDVAALVGDPGWRT----GPGDTVLMHASHAFD 646

Query: 655  LSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQL----- 709
            +S    W P   LL G  + +     + D   L   +A G +     T   F  L     
Sbjct: 647  ISLFEIWVP---LLSGARVMIAGPGAV-DGAALAAQVAAG-VTAAHLTAGAFRVLAEESP 701

Query: 710  -SAAGLLDHNLSVLALGGEAINTGLWDQLR-GLSQMAVYNCYGPTEMTVEXXXXXXK--D 765
             S AGL +     +  GG+A+     +++R     + V + YGPTE T+       +  D
Sbjct: 702  ESVAGLRE-----VLTGGDAVPLAAVERVRRACPDVRVRHLYGPTETTLCATWWLLEPGD 756

Query: 766  YRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVAD 823
               P   IG   AG   YV D+ LR +P G  GELY++GA +A+GY+GRP +TA RFVAD
Sbjct: 757  ETGPVLPIGRPLAGRRVYVLDAFLRPLPPGTTGELYVAGAGVAQGYLGRPALTAERFVAD 816

Query: 824  PLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAV 883
            P  PG RMYRTGDL      G  A+ GRAD QVKIRGYRVE GE+EA L G PGV  A V
Sbjct: 817  PFAPGGRMYRTGDLAYWTEQGTLAFAGRADDQVKIRGYRVEPGEVEAVLGGLPGVAQAVV 876

Query: 884  SVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLD 943
             V  +     L+G+VV +     D  +LRA L   LP +MVPA ++ L  LP+  NGK+D
Sbjct: 877  CVRGEH----LIGYVVAEAGRDLDPERLRARLAATLPEFMVPAAVLVLADLPLTVNGKVD 932

Query: 944  GHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSIVA 1002
              A   L E    + S G A   +T  ER+LC++F   L      ++D  F  G DSI +
Sbjct: 933  RPA---LPEPDFAAKSTGRA--PATAAERILCDVFAGVLGLDRVGVEDSFFALGGDSISS 987

Query: 1003 ISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQD--APADADYGAVRPLPMVSW 1060
            + +  +ARR+G+ + PR V    T  +L A   AA  ++   + ADA  G +   P++  
Sbjct: 988  MQVAARARREGIALTPRQVFEHRTPERLAALAPAAGSARPDRSAADAGLGEIPWTPVMRA 1047

Query: 1061 LYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPA 1120
            L +      F    ++  P+G+D  ++   L+ +LD HD LR+         RL+  E  
Sbjct: 1048 LGDDAVRPGFAQARVVVAPAGLDPDALTGALRAVLDTHDVLRA---RVEPDRRLIVPERG 1104

Query: 1121 AVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPAN 1180
            AV A D+LTR+ +     D + +     A      +DPSAG M+RA+W    +  A+P  
Sbjct: 1105 AVAAADLLTRVAV---DSDGIDARAEREAATAAGTLDPSAGIMLRAVWLDAGD--AEPGR 1159

Query: 1181 ILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQ 1240
             L L AHHL VD VSW I+L DL AA++ + AG  P + P  TSYR+W   +  +AS+P 
Sbjct: 1160 -LALVAHHLVVDAVSWSILLPDLQAAYQEVLAGATPALEPAATSYRQWARRLTEQASSPS 1218

Query: 1241 VQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVR 1300
               + D+W  ++   +P L   +      +WS       A+   +  R+ GA     G++
Sbjct: 1219 TLAELDHWVTVLDAAEPPLAEHHGQ--AHSWSA--TLSGAVAGHLVSRMPGAFH--CGIQ 1272

Query: 1301 ELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLG 1360
            E+LLA  A AVA WR        AGVLV +EGHGR  A    D   TVGWFT+  PVRL 
Sbjct: 1273 EVLLAGLAAAVARWR-----GDDAGVLVDVEGHGR-HAADGEDLLRTVGWFTSVHPVRL- 1325

Query: 1361 AGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQ 1418
               + VD+  A     AA +L+ SV   + A P DG  +GLLR++  D    L     PQ
Sbjct: 1326 -DVSGVDLAAAAAGDAAAGELLKSVKDQVRAAPGDGFGFGLLRHLNPDTAERLAALPAPQ 1384

Query: 1419 IQFSYLGRLDLGGVADQ--PWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQ 1476
            I F+YLGR    GVA +  PW +  G        +  PDL L   L     V  T +G  
Sbjct: 1385 IGFNYLGR---SGVAAEAVPWQVRGGSLGAG---EAGPDLVLAHPLEAGADVRDTPDGPL 1438

Query: 1477 L 1477
            L
Sbjct: 1439 L 1439



 Score =  643 bits (1658), Expect = 0.0
 Identities = 514/1542 (33%), Positives = 731/1542 (47%), Gaps = 97/1542 (6%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AAAP + D+  LSPLQ G+     L EDGVD+Y  Q ++D+DGP+D + LR + + ++ R
Sbjct: 1499 AAAPGLTDIWPLSPLQRGMLFERALDEDGVDVYQSQRILDLDGPLDADRLRAAWRTLVAR 1558

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWSER-VATPAEFDSIAR------SERRRPFDLS 115
            H +LR +F   +  + VQ+V   A + W    V+  AE D+ A        ++ + FD++
Sbjct: 1559 HESLRTSFHQLESGETVQVVVDQADIGWRVADVSHRAEADAAAEVGRLLAEDQAQRFDVT 1618

Query: 116  RGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXX 175
            R P LR++++ + G  + R++ T+HHI++DGWS  +   E+ A                 
Sbjct: 1619 RAPLLRLLLVRL-GADRHRLVVTSHHIVLDGWSTPIILGEMSAAYAGAPSTATAPSPRD- 1676

Query: 176  XXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQ 235
              Y+ WL +QD +A  A W   L G  EP +V  +A      PG+    L    T RL +
Sbjct: 1677 --YLAWLNRQDDAATRAAWRSELAGCDEPTLVDADADKTMVMPGEHCEGLSEQATRRLTE 1734

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
            +A  H +TL+T +  AWA+VL+RL  R DVVFGTVVSGRP ++P V+ MVG+FIN VPV 
Sbjct: 1735 FARGHAVTLSTILQGAWALVLARLAGRTDVVFGTVVSGRPAEVPDVDRMVGMFINTVPVR 1794

Query: 296  HYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIR 355
              + G   V+     +Q + SA+ +  +L L +IQR  G G LFD++ + EN P+D A  
Sbjct: 1795 VRLDGGRPVLDLLHDLQARQSALTEHQHLGLPDIQRAAGPGALFDTIMMVENYPMDAA-- 1852

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
                  G +   V   + T YPLT+ S                      AAE   +++ V
Sbjct: 1853 GLGGEGGVRIGSVLTRTGTSYPLTM-SASPGERLQIRVSYRPDRIERETAAEAAGQVVRV 1911

Query: 416  LRQL---PDIGDG----TPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXX 468
            + ++   P +  G    T + +  R      A G+ A  S+      V   F R+ +   
Sbjct: 1912 IERIVAEPSLAVGRLGVTGESVRERVVERWNATGVAAGGSS------VLTGFRRRARSSP 1965

Query: 469  XXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXX 528
                     G   +YA L   + RLAG LA  GV     V +V+ R              
Sbjct: 1966 DAVAVSGG-GRTLSYAALDRESDRLAGHLAGRGVRRGDRVGVVMERGTDLFVALLAIGKA 2024

Query: 529  XXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRS 588
               Y+PV++  P  R+E ++  A  ++A+     S  V   +  + +D PA    I+   
Sbjct: 2025 GAAYVPVNLDYPRDRIERMLTDAGVSVAVCVQATSGAVPDGLAPVVMDSPA----IAAAP 2080

Query: 589  AAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXX 648
            + AP +       AYV++TSGSTG PKGV   + +V +   D    V             
Sbjct: 2081 SEAPPITVGAHDLAYVMYTSGSTGVPKGVAVPHGSVAALAGDPGWSV----GPGDGVLMH 2136

Query: 649  XXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQ 708
              HA+  S    W P   LL G  + + D   + DA RL E I  G   +  T  S  V 
Sbjct: 2137 APHAFDASLLEIWVP---LLSGAHVVVADPGAV-DAQRLREAIDRGVTTVHLTAGSFRVL 2192

Query: 709  LSAAGLLDHNLSVLALGGEAINTGLWDQLRGLS-QMAVYNCYGPTEMTV----EXXXXXX 763
               +      L  +  GG+A+      +LR    ++ V + YGPTE T+           
Sbjct: 2193 AEESPDAFRGLREVLTGGDAVPLASVVRLRETCPEIRVRHLYGPTETTLCATWHLIEPGV 2252

Query: 764  KDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVAD 823
                   IG   AG   YV D+ L+ V   V GELYL+GA LARGY+G    TA RFVAD
Sbjct: 2253 ATGDTLPIGRPLAGRRAYVLDAFLQPVAPNVTGELYLAGAGLARGYLGAAAATAERFVAD 2312

Query: 824  PLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAV 883
            P   G+RMYRTGDL R    G   + GRAD QVKIRGYRVE  EIEAAL   P V  A V
Sbjct: 2313 PFAAGERMYRTGDLARWTEQGELLFAGRADAQVKIRGYRVEPAEIEAALTAIPEVAQAVV 2372

Query: 884  SVLRQQ--DRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGK 941
             V R+       L+ +V        D   +R  L ERLP +MVPA +V L   P+  NGK
Sbjct: 2373 -VAREDGPGEKRLIAYVTAAGQPGPDPAAVREHLGERLPEFMVPAAVVVLDGFPLTINGK 2431

Query: 942  LDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSI 1000
            +D  AL   A +     +G       T+ ERVLC+LF + L       DD  F  G DSI
Sbjct: 2432 IDRAALP--APERSGKPAGR---EPRTEVERVLCDLFADLLGLDRVGADDSFFELGGDSI 2486

Query: 1001 VAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSW 1060
            V++ L  +ARR+G+    + V    T   + AA+      + A  D   G V   P++  
Sbjct: 2487 VSMQLAARARREGVVFGAKDVFEQKTPAAI-AAVAVRGGQRPAGPDDGVGEVAWTPVMRG 2545

Query: 1061 LYEYG----NYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRS-ILTETPEGPRLV 1115
            L +      N       V +  P  + R  +   L  +LD HD LRS ++    E PRLV
Sbjct: 2546 LLDRDPGTMNRSAMAQWVTVGAPDTLSRDVLAAGLGAVLDAHDMLRSRVVAAGTEEPRLV 2605

Query: 1116 TREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHR 1175
                 AV A  ++ R+    G  D+L      +A     ++DP AG MVRA+W       
Sbjct: 2606 VAPRGAVHAAGLVDRVEAGAGEVDDLTE---RSAAEAATRLDPGAGVMVRAVWV-----D 2657

Query: 1176 ADPANI--LLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMW 1233
            A P  +  L++ AHHL VD VSW I+L DL AA  ++ AG  P + P   S+RRW   + 
Sbjct: 2658 AGPGRVGRLVVVAHHLVVDAVSWRILLPDLRAACEAVAAGREPALDPVDVSFRRWARTLT 2717

Query: 1234 HRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVD----VTERV 1289
             +A+      +   W  ++    P  G    DP RDT ST       +P D    + ERV
Sbjct: 2718 DQAATRTA--ELATWTRILGGAQPRFGAL--DPGRDTISTAGRRTWTVPQDRAGVLVERV 2773

Query: 1290 LGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVG 1349
              A     GV E+LLA  A AVA WR        A V+V +EGHGR   + + D + TVG
Sbjct: 2774 TSAFH--CGVHEVLLATLAGAVARWR------GGAAVVVDVEGHGRR-PLGEMDLSRTVG 2824

Query: 1350 WFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVA 1409
            WFT+  P+RL      +D  +      AA  L+ +V  ++ A+P+ GL YG+LR+++   
Sbjct: 2825 WFTDVHPLRL--DVTGIDTAEVIAGGGAAGRLLKTVKENVRAVPDGGLGYGMLRHLNAET 2882

Query: 1410 ELVDAVDP--QIQFSYLGRLDLGGVAD-QPWSLLTGPYLDALPIDPEPDLPLRFALNLSV 1466
              V A  P  +I F+YLGR   G   D QPW       L  +    EPD+PLR A+ +  
Sbjct: 2883 GRVLAAQPAAEIGFNYLGRFSEGPGGDVQPWQ-----QLGTIGGTAEPDMPLRHAVEIDA 2937

Query: 1467 FVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
             V   A+G +L     W+  +   ++ + L   WQ  +A LA
Sbjct: 2938 AVLDAADGPRLELTVTWAGRLVGAAEAESLGRAWQDVLAGLA 2979



 Score =  455 bits (1170), Expect = e-125
 Identities = 371/1075 (34%), Positives = 505/1075 (46%), Gaps = 76/1075 (7%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            + AA P + D+  LSPLQEGL   H + E G D+Y+    + +DGP+D+   R S QA+L
Sbjct: 3008 IEAAVPDLLDIWPLSPLQEGLL-FHAVDERGPDVYASMRTLAVDGPLDVARFRASWQAVL 3066

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATP-------AEFDSIARSERRRPFD 113
            DRH  LRA+F   +    VQ +     LPW E   +        AEFD +A   R   FD
Sbjct: 3067 DRHAALRASFHQLESGAAVQAIAREVTLPWQETDLSDLPEDVALAEFDRLAAQLRDERFD 3126

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            L+R P LR+ ++ + GE + R+ F +HHI  DGWSL +  TE++A               
Sbjct: 3127 LTRAPLLRLHLVRL-GERRHRLAFASHHISCDGWSLPIVSTEVMAAYEGRGLPAPTSYRD 3185

Query: 174  XXXXYIVWLAKQDRSAALAGWMDYLRGVSEPL-MVAYEATAGQSKPGKTELLLPAADTAR 232
                Y+VWLA+QD+ AA   W   L G+ E   +V  +       P +    L    + R
Sbjct: 3186 ----YLVWLARQDKEAARQAWRGELAGLDEATHVVPPDTITAPIAPQRVRFGLDDELSRR 3241

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L ++  RHG+T+NT     W+++L+RLT R DVVFG+ V+GRP ++PGV ++VGLF+N  
Sbjct: 3242 LVRFTRRHGVTMNTLFQGIWSLLLARLTGRDDVVFGSAVAGRPAEIPGVGSVVGLFMNTA 3301

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDD 352
            PV   + G E  +   T +QR+  AM    +L LSEI++  G G  FD+L VFEN P   
Sbjct: 3302 PVRVRLDGAEPFLDMLTDLQRRQVAMMAHQHLGLSEIKQVAGPGAAFDTLVVFENYPRPP 3361

Query: 353  AIRPATTPDGAQFLPVEM-ESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGER 411
              RP+  PD     P E+ E   HYP++    +R                    AE    
Sbjct: 3362 --RPSDDPDAVVMRPAEIPEDSGHYPVS----MRASEDGGVHGEFIFRPDAFDRAEAEGM 3415

Query: 412  MLTVLRQL------PDIGDGTPDDLDIRTAAELK-AHGLLAARSAPTFDTTVWEMFERQV 464
            +  ++  L      P I  G    + +  AAE +          AP     +  +F RQ 
Sbjct: 3416 LAAIIEALRQVVAEPGIAVGR---IGLVGAAERRQVVREWNETDAPLTAQPLPMLFRRQA 3472

Query: 465  QXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXX 524
            Q                ++  L   A  LA  L   GV         L RS         
Sbjct: 3473 Q-RSPDAVAVRDAARSLSFGALLGEAEGLARRLVASGVRRGDPGGRALERSAELVVALLG 3531

Query: 525  XXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLV--GTAVPTLALDDPAAVE 582
                   ++PVD   P  R+  ++  A+P + +  A    +V    A   LALD+P+A  
Sbjct: 3532 VSLAGGVFVPVDPDYPGDRIALMLADAAPQVLVCTARTRSVVPGDFAGAVLALDEPSA-- 3589

Query: 583  SISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXX 642
              +    + P V  R    AYVI+TSGSTG PKGV+ T+A + +  +   ER        
Sbjct: 3590 --AGPQVSLPRVAAR--DGAYVIYTSGSTGVPKGVLVTHAGLGNLASAQIER------FG 3639

Query: 643  XXXXXXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDT 701
                       +L FDA+   + + LL G  I L DAE M     L + +    I  +  
Sbjct: 3640 VTSSSRVLQFAALGFDAAISEVCMALLSGGSIVLADAEHMPPRVSLGDAVRRWDITHVTV 3699

Query: 702  TPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV--EXX 759
             PS+   L+    L  +L+ L + GEA    L D  R      + N YGPTE TV     
Sbjct: 3700 PPSV---LAVEDDLPDDLT-LIVAGEACPPALVD--RWSPGRRMINGYGPTETTVCATMS 3753

Query: 760  XXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAAR 819
                       IG   A    YV D+ L+ VP G+ GELY++G  LARGY+GRPG+TA R
Sbjct: 3754 SPLSPGRGAVPIGGPIANMRTYVLDAFLQPVPPGMTGELYVTGVGLARGYLGRPGLTAER 3813

Query: 820  FVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVH 879
            FVADP  PG RMYRTGD  R    G   + GR D QVK+RGYR+E GEIEA L   PGV 
Sbjct: 3814 FVADPFSPGGRMYRTGDRARWTGDGELVFAGRVDAQVKVRGYRIEPGEIEAVLAEHPGV- 3872

Query: 880  DAAVSVLRQQD---RTSLVGFVVWQDNMHEDLIKLRAGLTE----RLPSYMVPARIVTLP 932
             A V V+ +QD      LV +VV       +   L + L E    RLP +MVPA  V L 
Sbjct: 3873 -AQVVVVARQDGPGEKQLVAYVVPAAGPTAEASTLISALREAAAARLPEHMVPAAFVPLD 3931

Query: 933  RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDD 991
             +P+  NGK+D  AL   A D    +S G      T  E  LCELF E L       DD 
Sbjct: 3932 AMPLTPNGKVDHRALQ--APD-FAGMSAGR--DPRTALEAKLCELFAEVLGLEQVGADDS 3986

Query: 992  LFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD 1046
             F  G DSI ++ L  +ARR+GL + P  V    T  +L A +      ++ PAD
Sbjct: 3987 FFELGGDSITSMQLSTRARREGLELTPWQVFDEKTPERLAALV------KEIPAD 4035


>tr|Q70AZ7|Q70AZ7_ACTTI Tax_Id=1867 (tcp11)SubName: Full=Non-ribosomal
            peptide synthetase;[Actinoplanes teichomyceticus]
          Length = 4067

 Score =  726 bits (1874), Expect = 0.0
 Identities = 532/1501 (35%), Positives = 749/1501 (49%), Gaps = 96/1501 (6%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            +IED+  LSPLQEGL       ++G D+Y   +++D+DGPVD   LR + +A+L RH  L
Sbjct: 5    RIEDIWPLSPLQEGLLFHTVYDDEGPDVYVGHWILDLDGPVDAARLRAAWEALLARHAAL 64

Query: 67   RAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDS-------IARSERRRPFDLSRGPA 119
            RA F  R   + VQ+V     LPW  RV   A  D        +A  +R RPFD+++ P 
Sbjct: 65   RACFRQRRTGETVQVVAGRVELPW--RVVDLAHLDDPEHAVRELADEDRLRPFDVAKPPL 122

Query: 120  LRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYI 179
            LR+ ++ +  + + R++ T HH ++DGWSL + F EL A+                  Y+
Sbjct: 123  LRLTLIRL-ADDRHRLVVTCHHAVMDGWSLPIVFDELTALYAAGDGPAQLPAVTPYREYL 181

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSK--PGKTELLLPAADTARLRQWA 237
             WL++QD+ +ALA W   LRG  EP +VA  A  G++   P   E+ L    T  L + A
Sbjct: 182  AWLSRQDKPSALAAWAAELRGAQEPTLVA-PADPGRAPGMPESVEVQLSPELTRSLAELA 240

Query: 238  GRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHY 297
               GLTLNT +  AWA+VL+RLT R DVVFG  VS RP  LPGVE MVGLF+N VPV   
Sbjct: 241  RGRGLTLNTVIQGAWALVLARLTGRTDVVFGATVSARPAHLPGVEAMVGLFLNTVPVRVR 300

Query: 298  VSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAP--IDDAIR 355
            + G+  VV    ++Q++ SA+    ++ L++IQ+  G G +FD+L VFEN P  +DD+  
Sbjct: 301  LRGSAPVVEMLAELQKRQSALIPEQFVGLADIQKAAGPGAVFDTLLVFENFPRELDDS-- 358

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
               + D       +     HYPLT+V+ +                    AA I ER   V
Sbjct: 359  --RSADAFGIRVHQGREAAHYPLTLVA-VPGESMLFKLDYLTELFDAATAASILERFTRV 415

Query: 416  LRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXX 475
            LR+L D G+ T   +D+ +AAE        A      D    ++F RQV           
Sbjct: 416  LRRLTDAGELTVAAIDVTSAAERDRVARWGAAVGARPDRLALDLFARQVAQRPDEVAVAD 475

Query: 476  XXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPV 535
               V  ++ EL  RA RLAG L+  GV     VA+V+ RS                ++PV
Sbjct: 476  GDRVM-SFGELAERAERLAGHLSARGVRRGDRVAVVMERSGELIATLLAVWRAGAAFVPV 534

Query: 536  DVTLPSARVESIVRQASPALAITEADY-SQLVGTAVPTLALDDPAAVESISRRSAAAPTV 594
            D   P+ RV+ ++  A P  A+  A + + ++   +  + +DDP    ++    A  P V
Sbjct: 535  DPAYPAERVKFLLTDAEPVAAVCTAAFRAAVLDGGLEAIVVDDPGTWPAV----APCPPV 590

Query: 595  DRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWS 654
               P+  AYV++TSGSTG PKGV  ++  V +   D   R                HA+ 
Sbjct: 591  PTGPDDLAYVMYTSGSTGTPKGVAVSHGDVAALVGDPGWRT----GPGDTVLMHASHAFD 646

Query: 655  LSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQL----- 709
            +S    W P   LL G  + +     + D   L   +A G +     T   F  L     
Sbjct: 647  ISLFEIWVP---LLSGARVMIAGPGAV-DGAALAAQVAAG-VTAAHLTAGAFRVLAEESP 701

Query: 710  -SAAGLLDHNLSVLALGGEAINTGLWDQLR-GLSQMAVYNCYGPTEMTVEXXXXXXK--D 765
             S AGL +     +  GG+A+     +++R     + V + YGPTE T+       +  D
Sbjct: 702  ESVAGLRE-----VLTGGDAVPLAAVERVRRACPDVRVRHLYGPTETTLCATWWLLEPGD 756

Query: 766  YRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVAD 823
               P   IG   AG   YV D+ LR +P G  GELY++GA +A+GY+GRP +TA RFVAD
Sbjct: 757  ETGPVLPIGRPLAGRRVYVLDAFLRPLPPGTTGELYVAGAGVAQGYLGRPALTAERFVAD 816

Query: 824  PLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAV 883
            P  PG RMYRTGDL      G  A+ GRAD QVKIRGYRVE GE+EA L G PGV  A V
Sbjct: 817  PFAPGGRMYRTGDLAYWTEQGTLAFAGRADDQVKIRGYRVEPGEVEAVLGGLPGVAQAVV 876

Query: 884  SVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLD 943
             V  +     L+G+VV +     D  +LRA L   LP +MVPA ++ L  LP+  NGK+D
Sbjct: 877  CVRGEH----LIGYVVAEAGRDLDPERLRARLAATLPEFMVPAAVLVLADLPLTVNGKVD 932

Query: 944  GHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSIVA 1002
              A   L E    + S G A   +T  ER+LC++F   L      ++D  F  G DSI +
Sbjct: 933  RPA---LPEPDFAAKSTGRA--PATAAERILCDVFAGVLGLDRVGVEDSFFALGGDSISS 987

Query: 1003 ISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQD--APADADYGAVRPLPMVSW 1060
            + +  +ARR+G+ + PR V    T  +L A   AA  ++   + ADA  G +   P++  
Sbjct: 988  MQVAARARREGIALTPRQVFEHRTPERLAALAPAAGSARPDRSAADAGLGEIPWTPVMRA 1047

Query: 1061 LYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPA 1120
            L +      F    ++  P+G+D  ++   L+ +LD HD LR+         RL+  E  
Sbjct: 1048 LGDDAVRPGFAQARVVVAPAGLDPDALTGALRAVLDTHDVLRA---RVEPDRRLIVPERG 1104

Query: 1121 AVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPAN 1180
            AV A D+LTR+ +     D + +     A      +DPSAG M+RA+W    +  A+P  
Sbjct: 1105 AVAAADLLTRVAV---DSDGIDARAEREAATAAGTLDPSAGIMLRAVWLDAGD--AEPGR 1159

Query: 1181 ILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQ 1240
             L L AHHL VD VSW I+L DL AA++ + AG  P + P  TSYR+W   +  +AS+P 
Sbjct: 1160 -LALVAHHLVVDAVSWSILLPDLQAAYQEVLAGATPALEPAATSYRQWARRLTEQASSPS 1218

Query: 1241 VQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVR 1300
               + D+W  ++   +P L   +      +WS       A+   +  R+ GA     G++
Sbjct: 1219 TLAELDHWVTVLDAAEPPLAEHHGQ--AHSWSA--TLSGAVAGHLVSRMPGAFH--CGIQ 1272

Query: 1301 ELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLG 1360
            E+LLA  A AVA WR        AGVLV +EGHGR  A    D   TVGWFT+  PVRL 
Sbjct: 1273 EVLLAGLAAAVARWR-----GDDAGVLVDVEGHGR-HAADGEDLLRTVGWFTSVHPVRL- 1325

Query: 1361 AGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQ 1418
               + VD+  A     AA +L+ SV   + A P DG  +GLLR++  D    L     PQ
Sbjct: 1326 -DVSGVDLAAAAAGDAAAGELLKSVKDQVRAAPGDGFGFGLLRHLNPDTAERLAALPAPQ 1384

Query: 1419 IQFSYLGRLDLGGVADQ--PWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQ 1476
            I F+YLGR    GVA +  PW +  G        +  PDL L   L     V  T +G  
Sbjct: 1385 IGFNYLGR---SGVAAEAVPWQVRGGSLGAG---EAGPDLVLAHPLEAGADVRDTPDGPL 1438

Query: 1477 L 1477
            L
Sbjct: 1439 L 1439



 Score =  643 bits (1658), Expect = 0.0
 Identities = 514/1542 (33%), Positives = 731/1542 (47%), Gaps = 97/1542 (6%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AAAP + D+  LSPLQ G+     L EDGVD+Y  Q ++D+DGP+D + LR + + ++ R
Sbjct: 1499 AAAPGLTDIWPLSPLQRGMLFERALDEDGVDVYQSQRILDLDGPLDADRLRAAWRTLVAR 1558

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWSER-VATPAEFDSIAR------SERRRPFDLS 115
            H +LR +F   +  + VQ+V   A + W    V+  AE D+ A        ++ + FD++
Sbjct: 1559 HESLRTSFHQLESGETVQVVVDQADIGWRVADVSHRAEADAAAEVGRLLAEDQAQRFDVT 1618

Query: 116  RGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXX 175
            R P LR++++ + G  + R++ T+HHI++DGWS  +   E+ A                 
Sbjct: 1619 RAPLLRLLLVRL-GADRHRLVVTSHHIVLDGWSTPIILGEMSAAYAGAPSTATAPSPRD- 1676

Query: 176  XXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQ 235
              Y+ WL +QD +A  A W   L G  EP +V  +A      PG+    L    T RL +
Sbjct: 1677 --YLAWLNRQDDAATRAAWRSELAGCDEPTLVDADADKTMVMPGEHCEGLSEQATRRLTE 1734

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
            +A  H +TL+T +  AWA+VL+RL  R DVVFGTVVSGRP ++P V+ MVG+FIN VPV 
Sbjct: 1735 FARGHAVTLSTILQGAWALVLARLAGRTDVVFGTVVSGRPAEVPDVDRMVGMFINTVPVR 1794

Query: 296  HYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIR 355
              + G   V+     +Q + SA+ +  +L L +IQR  G G LFD++ + EN P+D A  
Sbjct: 1795 VRLDGGRPVLDLLHDLQARQSALTEHQHLGLPDIQRAAGPGALFDTIMMVENYPMDAA-- 1852

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
                  G +   V   + T YPLT+ S                      AAE   +++ V
Sbjct: 1853 GLGGEGGVRIGSVLTRTGTSYPLTM-SASPGERLQIRVSYRPDRIERETAAEAAGQVVRV 1911

Query: 416  LRQL---PDIGDG----TPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXX 468
            + ++   P +  G    T + +  R      A G+ A  S+      V   F R+ +   
Sbjct: 1912 IERIVAEPSLAVGRLGVTGESVRERVVERWNATGVAAGGSS------VLTGFRRRARSSP 1965

Query: 469  XXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXX 528
                     G   +YA L   + RLAG LA  GV     V +V+ R              
Sbjct: 1966 DAVAVSGG-GRTLSYAALDRESDRLAGHLAGRGVRRGDRVGVVMERGTDLFVALLAIGKA 2024

Query: 529  XXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRS 588
               Y+PV++  P  R+E ++  A  ++A+     S  V   +  + +D PA    I+   
Sbjct: 2025 GAAYVPVNLDYPRDRIERMLTDAGVSVAVCVQATSGAVPDGLAPVVMDSPA----IAAAP 2080

Query: 589  AAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXX 648
            + AP +       AYV++TSGSTG PKGV   + +V +   D    V             
Sbjct: 2081 SEAPPITVGAHDLAYVMYTSGSTGVPKGVAVPHGSVAALAGDPGWSV----GPGDGVLMH 2136

Query: 649  XXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQ 708
              HA+  S    W P   LL G  + + D   + DA RL E I  G   +  T  S  V 
Sbjct: 2137 APHAFDASLLEIWVP---LLSGAHVVVADPGAV-DAQRLREAIDRGVTTVHLTAGSFRVL 2192

Query: 709  LSAAGLLDHNLSVLALGGEAINTGLWDQLRGLS-QMAVYNCYGPTEMTV----EXXXXXX 763
               +      L  +  GG+A+      +LR    ++ V + YGPTE T+           
Sbjct: 2193 AEESPDAFRGLREVLTGGDAVPLASVVRLRETCPEIRVRHLYGPTETTLCATWHLIEPGV 2252

Query: 764  KDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVAD 823
                   IG   AG   YV D+ L+ V   V GELYL+GA LARGY+G    TA RFVAD
Sbjct: 2253 ATGDTLPIGRPLAGRRAYVLDAFLQPVAPNVTGELYLAGAGLARGYLGAAAATAERFVAD 2312

Query: 824  PLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAV 883
            P   G+RMYRTGDL R    G   + GRAD QVKIRGYRVE  EIEAAL   P V  A V
Sbjct: 2313 PFAAGERMYRTGDLARWTEQGELLFAGRADAQVKIRGYRVEPAEIEAALTAIPEVAQAVV 2372

Query: 884  SVLRQQ--DRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGK 941
             V R+       L+ +V        D   +R  L ERLP +MVPA +V L   P+  NGK
Sbjct: 2373 -VAREDGPGEKRLIAYVTAAGQPGPDPAAVREHLGERLPEFMVPAAVVVLDGFPLTINGK 2431

Query: 942  LDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSI 1000
            +D  AL   A +     +G       T+ ERVLC+LF + L       DD  F  G DSI
Sbjct: 2432 IDRAALP--APERSGKPAGR---EPRTEVERVLCDLFADLLGLDRVGADDSFFELGGDSI 2486

Query: 1001 VAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSW 1060
            V++ L  +ARR+G+    + V    T   + AA+      + A  D   G V   P++  
Sbjct: 2487 VSMQLAARARREGVVFGAKDVFEQKTPAAI-AAVAVRGGQRPAGPDDGVGEVAWTPVMRG 2545

Query: 1061 LYEYG----NYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRS-ILTETPEGPRLV 1115
            L +      N       V +  P  + R  +   L  +LD HD LRS ++    E PRLV
Sbjct: 2546 LLDRDPGTMNRSAMAQWVTVGAPDTLSRDVLAAGLGAVLDAHDMLRSRVVAAGTEEPRLV 2605

Query: 1116 TREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHR 1175
                 AV A  ++ R+    G  D+L      +A     ++DP AG MVRA+W       
Sbjct: 2606 VAPRGAVHAAGLVDRVEAGAGEVDDLTE---RSAAEAATRLDPGAGVMVRAVWV-----D 2657

Query: 1176 ADPANI--LLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMW 1233
            A P  +  L++ AHHL VD VSW I+L DL AA  ++ AG  P + P   S+RRW   + 
Sbjct: 2658 AGPGRVGRLVVVAHHLVVDAVSWRILLPDLRAACEAVAAGREPALDPVDVSFRRWARTLT 2717

Query: 1234 HRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVD----VTERV 1289
             +A+      +   W  ++    P  G    DP RDT ST       +P D    + ERV
Sbjct: 2718 DQAATRTA--ELATWTRILGGAQPRFGAL--DPGRDTISTAGRRTWTVPQDRAGVLVERV 2773

Query: 1290 LGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVG 1349
              A     GV E+LLA  A AVA WR        A V+V +EGHGR   + + D + TVG
Sbjct: 2774 TSAFH--CGVHEVLLATLAGAVARWR------GGAAVVVDVEGHGRR-PLGEMDLSRTVG 2824

Query: 1350 WFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVA 1409
            WFT+  P+RL      +D  +      AA  L+ +V  ++ A+P+ GL YG+LR+++   
Sbjct: 2825 WFTDVHPLRL--DVTGIDTAEVIAGGGAAGRLLKTVKENVRAVPDGGLGYGMLRHLNAET 2882

Query: 1410 ELVDAVDP--QIQFSYLGRLDLGGVAD-QPWSLLTGPYLDALPIDPEPDLPLRFALNLSV 1466
              V A  P  +I F+YLGR   G   D QPW       L  +    EPD+PLR A+ +  
Sbjct: 2883 GRVLAAQPAAEIGFNYLGRFSEGPGGDVQPWQ-----QLGTIGGTAEPDMPLRHAVEIDA 2937

Query: 1467 FVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
             V   A+G +L     W+  +   ++ + L   WQ  +A LA
Sbjct: 2938 AVLDAADGPRLELTVTWAGRLVGAAEAESLGRAWQDVLAGLA 2979



 Score =  464 bits (1195), Expect = e-128
 Identities = 373/1075 (34%), Positives = 514/1075 (47%), Gaps = 76/1075 (7%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            + AA P + D+  LSPLQEGL   H + E G D+Y+    + +DGP+D+   R S QA+L
Sbjct: 3008 IEAAVPDLLDIWPLSPLQEGLL-FHAVDERGPDVYASMRTLAVDGPLDVARFRASWQAVL 3066

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATP-------AEFDSIARSERRRPFD 113
            DRH  LRA+F   +    VQ +     LPW E   +        AEFD +A   R   FD
Sbjct: 3067 DRHAALRASFHQLESGAAVQAIAREVTLPWQETDLSDLPEDVALAEFDRLAAQLRDERFD 3126

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            L+R P LR+ ++ + GE + R+ F +HHI  DGWSL +  TE++A               
Sbjct: 3127 LTRAPLLRLHLVRL-GERRHRLAFASHHISCDGWSLPIVSTEVMAAYEGRGLPAPTSYRD 3185

Query: 174  XXXXYIVWLAKQDRSAALAGWMDYLRGVSEPL-MVAYEATAGQSKPGKTELLLPAADTAR 232
                Y+VWLA+QD+ AA   W   L G+ E   +V  +       P +    L    + R
Sbjct: 3186 ----YLVWLARQDKEAARQAWRGELAGLDEATHVVPPDTITAPIAPQRVRFGLDDELSRR 3241

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L ++  RHG+T+NT     W+++L+RLT R DVVFG+ V+GRP ++PGV ++VGLF+N +
Sbjct: 3242 LVRFTRRHGVTMNTLFQGIWSLLLARLTGRDDVVFGSAVAGRPAEIPGVGSVVGLFMNTL 3301

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDD 352
            PV   + G E  +   T +QR+  AM    +L LSEI++  G G  FD+L VFEN P   
Sbjct: 3302 PVRVRLDGAEPFLDMLTDLQRRQVAMMAHQHLGLSEIKQVAGPGAAFDTLVVFENYPRPP 3361

Query: 353  AIRPATTPDGAQFLPVEM-ESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGER 411
              RP+  PD     P E+ E   HYP++    +R                    AE    
Sbjct: 3362 --RPSDDPDAVVMRPAEIPEDSGHYPVS----MRASEDGGVHGEFIFRPDAFDRAEAEGM 3415

Query: 412  MLTVLRQL------PDIGDGTPDDLDIRTAAELK-AHGLLAARSAPTFDTTVWEMFERQV 464
            +  ++  L      P I  G    + +  AAE +          AP     +  +F RQ 
Sbjct: 3416 LAAIIEALRQVVAEPGIAVGR---IGLVGAAERRQVVREWNETDAPLTAQPLPMLFRRQA 3472

Query: 465  QXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXX 524
            Q                ++  L   A  LA  L   GV  ET VA+++ RS         
Sbjct: 3473 QRSPDAVAVRDAARSL-SFGALLGEAEGLARRLVASGVRRETRVAVLVERSAELVVALLG 3531

Query: 525  XXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLV--GTAVPTLALDDPAAVE 582
                   ++PVD   P  R+  ++  A+P + +  A    +V    A   LALD+P+A  
Sbjct: 3532 VSLAGGVFVPVDPDYPGDRIALMLADAAPQVLVCTARTRSVVPGDFAGAVLALDEPSAAG 3591

Query: 583  SISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXX 642
                   + P V  R    AYVI+TSGSTG PKGV+ T+A + +  +   ER        
Sbjct: 3592 P----QVSLPRVAAR--DGAYVIYTSGSTGVPKGVLVTHAGLGNLASAQIERFGVTSSSR 3645

Query: 643  XXXXXXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDT 701
                       +L FDA+   + + LL G  I L DAE M     L + +    I  +  
Sbjct: 3646 VLQFA------ALGFDAAISEVCMALLSGGSIVLADAEHMPPRVSLGDAVRRWDITHVTV 3699

Query: 702  TPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXX 761
             PS+   L+    L  +L+++ + GEA    L D+     +M   N YGPTE TV     
Sbjct: 3700 PPSV---LAVEDDLPDDLTLI-VAGEACPPALVDRWSPGRRMI--NGYGPTETTVCATMS 3753

Query: 762  XXKDYRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAAR 819
                  +    IG   A    YV D+ L+ VP G+ GELY++G  LARGY+GRPG+TA R
Sbjct: 3754 SPLSPGRGAVPIGGPIANMRTYVLDAFLQPVPPGMTGELYVTGVGLARGYLGRPGLTAER 3813

Query: 820  FVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVH 879
            FVADP  PG RMYRTGD  R    G   + GR D QVK+RGYR+E GEIEA L   PGV 
Sbjct: 3814 FVADPFSPGGRMYRTGDRARWTGDGELVFAGRVDAQVKVRGYRIEPGEIEAVLAEHPGV- 3872

Query: 880  DAAVSVLRQQD---RTSLVGFVVWQDNMHEDLIKLRAGLTE----RLPSYMVPARIVTLP 932
             A V V+ +QD      LV +VV       +   L + L E    RLP +MVPA  V L 
Sbjct: 3873 -AQVVVVARQDGPGEKQLVAYVVPAAGPTAEASTLISALREAAAARLPEHMVPAAFVPLD 3931

Query: 933  RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDD 991
             +P+  NGK+D  AL   A D    +S G      T  E  LCELF E L       DD 
Sbjct: 3932 AMPLTPNGKVDHRALQ--APD-FAGMSAGR--DPRTALEAKLCELFAEVLGLEQVGADDS 3986

Query: 992  LFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD 1046
             F  G DSI ++ L  +ARR+GL + P  V    T  +L A +      ++ PAD
Sbjct: 3987 FFELGGDSITSMQLSTRARREGLELTPWQVFDEKTPERLAALV------KEIPAD 4035


>tr|O85020|O85020_MYCSM Tax_Id=1772 (fxbC)SubName: Full=FxbC; Flags:
            Fragment;[Mycobacterium smegmatis]
          Length = 2129

 Score =  724 bits (1868), Expect = 0.0
 Identities = 531/1562 (33%), Positives = 739/1562 (47%), Gaps = 105/1562 (6%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            Q+ED+ A+SPLQ G++    LA+ G   Y  Q V + D  +D++ +RR+  A+L RHP L
Sbjct: 481  QVEDIWAMSPLQLGVYYQSTLADAG-PTYIAQNVFEFDRRIDVDAMRRAFTALLRRHPQL 539

Query: 67   RAAFWDRD------VPKPVQIVPVHAALPWSERVAT-------PAEFDSIARSERRRPFD 113
            RA F   +       P    +V V    P S+           PA    I  ++R  PFD
Sbjct: 540  RAGFRTVEHAEPEPAPDATPVVQVVVTDPPSDLTVVDLTDQDDPAAAQHIVDTDRTAPFD 599

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            ++  P LR+ V+ +PG  + RM+FT H +L DGWS  +   +L A+              
Sbjct: 600  VATPPLLRLTVIRLPGG-RDRMLFTYHFLLFDGWSRELVLRDLFALYDSDAQHGAIAPHG 658

Query: 174  XXXX-YIVWLAKQ---DRSAALAGWMDYLRGVSEPLMVAY------EATAGQSKPGKTEL 223
                 ++ WLA       S A   W D L G++EP + +       +A  G ++PG+  +
Sbjct: 659  DLVVRHLQWLATDGDPQASGARDAWRDLLAGLTEPTLASGVSPDHPDARPG-TEPGRIVV 717

Query: 224  LLPAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVET 283
             +P   T +L   A  HG TLN+ V  A A+V        DVV GT V+GRP  L G++ 
Sbjct: 718  RVPEDVTTQLHTCATAHGATLNSVVTAAVALVTGYHAGTTDVVIGTTVAGRPGHLVGIDE 777

Query: 284  MVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRG--PLFDS 341
             +GLF+N VPV   +S T +V A    +  Q  AM    +L L +IQR  G     LFDS
Sbjct: 778  TIGLFLNTVPVRVDMSPTRSVAAAMASIGEQRVAMMRHDHLGLGQIQRAAGDSGSALFDS 837

Query: 342  LFVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXP 401
            L V +N   DD      +  G   + V     TH+PLT V                    
Sbjct: 838  LLVLQNFLDDDTFTDLESRHG--IVDVSYHDTTHFPLTWVL---TPGRELAIKLEHRVVD 892

Query: 402  YLPAAEIGERMLTVLRQL---PDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWE 458
               A E+ E+++TVLR +   PD   G  D +     A+L+       R  P    T+ E
Sbjct: 893  DARATEMVEQLVTVLRTIAAEPDTAVGAVDLIGADRRAQLERRWSSTER--PLEPVTIAE 950

Query: 459  MFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS 518
            +  R+ +                TY E   R  + A  L   G  PET VAL LPRS   
Sbjct: 951  LLARRAEQNPDDVALVFG-AQSVTYREFDDRVSQFARHLRARGAAPETFVALALPRSIDM 1009

Query: 519  XXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTA----VPTLA 574
                         YLP+++ LP  R+ +I+  A P L +T  D ++L+G A       +A
Sbjct: 1010 VVALFAVLRAGAAYLPLELDLPIDRLRTIIDNAEPVLLVTTTDRTELIGHARARGADVIA 1069

Query: 575  LDDPAAVESISRRSAAAPTVDR---------RPEQSAYVIFTSGSTGEPKGVVGTNAAVL 625
            LDD     +++   A   T            R    AY+I+TSGSTG PKGV+   A + 
Sbjct: 1070 LDDAETAATLADTPAHPLTAGELGAFASDSTRLNHPAYLIYTSGSTGRPKGVLTGYAGLT 1129

Query: 626  SYFADHAERVYXXXXXXXXXXXXXX--HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRD 683
            + + +H E ++                H  S SFD SW+ +  L++GH++H+ D E  RD
Sbjct: 1130 NMYFNHREAIFAPTVARAGSAEQLRIAHTVSFSFDMSWEELFWLVEGHQVHVCDEELRRD 1189

Query: 684  ADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLD---HNLSVLALGGEAINTGLWDQLRGL 740
            A  LV      +ID+I+ TP+    L  AGLLD   H   ++ LGGEA+  G+W  LR  
Sbjct: 1190 APALVAYCHRHRIDVINVTPTYAHHLFDAGLLDDGAHTPPLVLLGGEAVGDGVWSALRDH 1249

Query: 741  SQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYL 800
               A YN YGPTE T+        D   PT+G     T GY+ D+ALR VPDG VGELY+
Sbjct: 1250 PDSAGYNLYGPTEYTINTLGGGTDDSDTPTVGQPIWNTRGYILDAALRPVPDGAVGELYI 1309

Query: 801  SGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGG--YAYVGRADTQVKI 858
            +G  LA GY  R G+TAA  VADP  PG RMYRTGDLVRR         Y+GR D QVKI
Sbjct: 1310 AGTGLALGYHRRAGLTAATMVADPYVPGGRMYRTGDLVRRRPGSAELLDYLGRVDDQVKI 1369

Query: 859  RGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRT----SLVGFVV---WQDNMHEDLIKL 911
            RGYRVE+GEIE+ L    GV   AV V R         +L  +V+   W       +  L
Sbjct: 1370 RGYRVELGEIESVLTRADGVARCAV-VARATGANPPVKTLAAYVIPDRWPAEDAAFITGL 1428

Query: 912  RAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTE 971
            R  L   LP YMVP R   +  LP+  NGKLD  AL         + + GT  +  TD E
Sbjct: 1429 RDHLARVLPGYMVPTRYGIVDTLPLTINGKLDVAALPE-----PIAATSGTGRTPRTDRE 1483

Query: 972  RVLCELFEEQLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQL 1030
              L E+    L      +DDD F  G DSI +IS+  +AR+ GL + PR V    TI  L
Sbjct: 1484 ATLLEIVASVLGIDGIGVDDDFFTLGGDSISSISVCGRARKAGLNITPRDVFRRRTIAAL 1543

Query: 1031 GAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGN-YRRFTHTVLLRLPSGIDRSSIEL 1089
             A+ D     +  P D   GA+   PM++   +       F   ++L  P+GI    ++ 
Sbjct: 1544 AASADTTQTPESGP-DTGTGAITATPMLAETAQANTPLTNFYQAMVLATPAGITADEVQR 1602

Query: 1090 MLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAA 1149
            +LQ ++D H  LR+ L  T  G  L   +  A     V +     +  + E A+A A   
Sbjct: 1603 VLQTVVDAHAMLRARLVTTATGWTLTVPDQTAAIGLTVRSGALTSDCVEAEKAAAAA--- 1659

Query: 1150 RVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRS 1209
                 ++DP AG MVRA+WF   E     +  LLL  HHL +D VSW I+  DL+ AW  
Sbjct: 1660 -----ELDPRAGNMVRAVWFDAPE----ASGQLLLVIHHLVIDGVSWRILSEDLSRAWND 1710

Query: 1210 LQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRD 1269
            L AG         TS+  W   +  R       D+ +YWA ++  PDP LG R PDP  D
Sbjct: 1711 LAAGRDVAADAVPTSFHTWANALAQRT----FDDESEYWADVLATPDPDLGSRPPDPAID 1766

Query: 1270 TWSTLQLTRAAIPVDVTERVLGAV--RRDQGVRELLLAATAMAVASWRRVRAQDPAAGVL 1327
            T  T++     +  DVTE +L +V      GV ++LL   A+A+A WR  R        +
Sbjct: 1767 TADTVRSHEVTLASDVTEALLTSVPAAMHGGVNDVLLTGLAVALAQWRADRGHSQNTAAV 1826

Query: 1328 VALEGHGRADAVL--DTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSV 1385
            ++LEGHGR   ++  D D + TVGWFT+ +PVR+  G    D  ++    +AA     +V
Sbjct: 1827 ISLEGHGRESDLVAADLDLSRTVGWFTSIYPVRIDPGPLEWDTVRSAGAELAA--AAKAV 1884

Query: 1386 VSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYL 1445
               L A+PN GL YG+LR++ G    +D   PQI F+YLGR   G   D  W  + G  +
Sbjct: 1885 KEQLRAVPNRGLGYGVLRHLHGA---LDGTPPQILFNYLGRFTGGSGND--WRPVAG--I 1937

Query: 1446 DALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIA 1505
             AL    +P  P   +L ++       +GT L     W   + +  D+  L  +W   + 
Sbjct: 1938 GALTEGVDPSNP-AMSLEINALAEERPDGTVLSMTLAWPGGLLDADDVSELGSMWADVLV 1996

Query: 1506 AL 1507
            AL
Sbjct: 1997 AL 1998



 Score =  216 bits (551), Expect = 2e-53
 Identities = 252/829 (30%), Positives = 355/829 (42%), Gaps = 85/829 (10%)

Query: 574  ALDDPAAVESISRRSAAAP--TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADH 631
            AL     V S +   AA P   V      +  V++TSGSTGEPK VVGT+AA+ +  A  
Sbjct: 4    ALPADTIVVSTTATHAAVPFTPVPVDGADAVSVLYTSGSTGEPKAVVGTHAALANRLAWA 63

Query: 632  AERVYXXXXXXXXXXXXXXHAWSLSF-DASWQPMVGLLDGHEIHLFDAEEMRDADRLVEG 690
             E                     LSF D + + + GL  G    L   E  RD  RL + 
Sbjct: 64   VEA---------WPAATRIAKSPLSFIDGTTELLAGLAAGARTVLAGDETARDGRRLAQL 114

Query: 691  IAIGQIDMIDTTPSMFVQLSAAGLLD-HNLSVLALGGEAINTGLWDQLRGLSQMA-VYNC 748
            +A   ++ +   PS+   L+     D   L+   + GEA+       LR     A + N 
Sbjct: 115  VAAHGVEQLLAVPSLAAVLADERTEDVAELNRWIVSGEALEPRHLHALRTACPTAEIVNS 174

Query: 749  YGPTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARG 808
            YG +E+  +       D    T+G A  G    + DS LR +P GV+GE+Y++G QLARG
Sbjct: 175  YGSSEVAGDVLAGVQDD-AGITLGAAVPGAGIRILDSRLRQLPAGVIGEIYVTGGQLARG 233

Query: 809  YVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEI 868
            Y+GRPG TA RFVA P   G+RMYRTGDL   L  G   + GRAD Q+KI G+RVE GEI
Sbjct: 234  YLGRPGQTATRFVAAP--GGERMYRTGDLGALLPGGRVVFAGRADDQLKINGHRVEPGEI 291

Query: 869  EAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARI 928
            E+ L  QPGV +AAV        T L  FVV + +       L   ++  LP ++VP+ +
Sbjct: 292  ESVLARQPGVREAAVI----GTGTQLAAFVVLESDA-PGAGDLLTAVSAELPGHLVPSSL 346

Query: 929  VTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-H 987
              +  +P+  NGK D +AL  L    +   S GTA   + D ER + ++    L   P  
Sbjct: 347  RPVDAIPLLPNGKRDNNALRSL---LVPGESTGTA--PTNDVERAVLDVMTGVLGRDPLG 401

Query: 988  IDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADA 1047
             DDD F  G DSI AI +  +  R G  +    V    T   + A +D         A  
Sbjct: 402  ADDDFFAVGGDSISAIRVTSRLARAGYHIATEDVFRGRTAAGVAALVDTVESLAHDAAIE 461

Query: 1048 DYGAVRPLPM-VSWLYEYGNYRRFTHTVLLRL------------PSGIDRSSIELMLQLL 1094
             +  VR  P  +  + E G          L+L            P+ I ++  E   ++ 
Sbjct: 462  PFATVRLSPQTIDRIRESGQVEDIWAMSPLQLGVYYQSTLADAGPTYIAQNVFEFDRRID 521

Query: 1095 LDG-HDTLRSILTETPE---GPRLVTR---EPA-------AVRAEDVLTRITLPEGSDDE 1140
            +D       ++L   P+   G R V     EPA        V   D  + +T+ + +D +
Sbjct: 522  VDAMRRAFTALLRRHPQLRAGFRTVEHAEPEPAPDATPVVQVVVTDPPSDLTVVDLTDQD 581

Query: 1141 LASAVAHAARVVTDQ---IDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWH 1197
              +A  H   V TD+    D +   ++R    R    R    + +L T H L  D  S  
Sbjct: 582  DPAAAQHI--VDTDRTAPFDVATPPLLRLTVIRLPGGR----DRMLFTYHFLLFDGWSRE 635

Query: 1198 IMLGDLAAAWRS-LQAGTPPKILPEFTSYRRWCELMWHRASA-PQVQDQRDYWAAL---V 1252
            ++L DL A + S  Q G    I P      R   L W      PQ    RD W  L   +
Sbjct: 636  LVLRDLFALYDSDAQHGA---IAPHGDLVVR--HLQWLATDGDPQASGARDAWRDLLAGL 690

Query: 1253 REPDPALGLR--YPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMA 1310
             EP  A G+   +PD    T     + R  +P DVT + L       G     +   A+A
Sbjct: 691  TEPTLASGVSPDHPDARPGTEPGRIVVR--VPEDVTTQ-LHTCATAHGATLNSVVTAAVA 747

Query: 1311 VASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRL 1359
            + +       D   G  VA    GR   ++  D   T+G F N  PVR+
Sbjct: 748  LVTGYHAGTTDVVIGTTVA----GRPGHLVGID--ETIGLFLNTVPVRV 790



 Score = 58.5 bits (140), Expect = 7e-06
 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 2/101 (1%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            ++E+VL L PLQEG++      +   D Y +Q +  + GPVD E+LR S   ++ RH  L
Sbjct: 2030 EVEEVLPLLPLQEGMYFHSMFGDPATDTYRVQQIAQLSGPVDPEVLRTSLTVVMRRHQAL 2089

Query: 67   RAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSE 107
            RA+F +    +  Q+  + + +P    V    + +SIA  E
Sbjct: 2090 RASFNELTDGRVAQV--IWSDVPVQLTVVDTDDLESIAAEE 2128


>tr|A0QNF1|A0QNF1_MYCS2 Tax_Id=246196 SubName: Full=Amino acid
            adenylation;[Mycobacterium smegmatis]
          Length = 7523

 Score =  723 bits (1867), Expect = 0.0
 Identities = 531/1562 (33%), Positives = 739/1562 (47%), Gaps = 105/1562 (6%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            Q+ED+ A+SPLQ G++    LA+ G   Y  Q V + D  +D++ +RR+  A+L RHP L
Sbjct: 2130 QVEDIWAMSPLQLGVYYQSTLADAG-PTYIAQNVFEFDRRIDVDAMRRAFTALLRRHPQL 2188

Query: 67   RAAFWDRD------VPKPVQIVPVHAALPWSERVAT-------PAEFDSIARSERRRPFD 113
            RA F   +       P    +V V    P S+           PA    I  ++R  PFD
Sbjct: 2189 RAGFRTVEHAEPEPAPDATPVVQVVVTDPPSDLTVVDLTDQDDPAAAQHIVDTDRTAPFD 2248

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            ++  P LR+ V+ +PG  + RM+FT H +L DGWS  +   +L A+              
Sbjct: 2249 VATPPLLRLTVIRLPGG-RDRMLFTYHFLLFDGWSRELVLRDLFALYDSDAQHGAIAPHG 2307

Query: 174  XXXX-YIVWLAKQ---DRSAALAGWMDYLRGVSEPLMVAY------EATAGQSKPGKTEL 223
                 ++ WLA       S A   W D L G++EP + +       +A  G ++PG+  +
Sbjct: 2308 DLVVRHLQWLATDGDPQASGARDAWRDLLAGLTEPTLASGVSPDHPDARPG-TEPGRIVV 2366

Query: 224  LLPAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVET 283
             +P   T +L   A  HG TLN+ V  A A+V        DVV GT V+GRP  L G++ 
Sbjct: 2367 RVPEDVTTQLHTCATAHGATLNSVVTAAVALVTGYHAGTTDVVIGTTVAGRPGHLVGIDE 2426

Query: 284  MVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRG--PLFDS 341
             +GLF+N VPV   +S T +V A    +  Q  AM    +L L +IQR  G     LFDS
Sbjct: 2427 TIGLFLNTVPVRVDMSPTRSVAAAMASIGEQRVAMMRHDHLGLGQIQRAAGDSGSALFDS 2486

Query: 342  LFVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXP 401
            L V +N   DD      +  G   + V     TH+PLT V                    
Sbjct: 2487 LLVLQNFLDDDTFTDLESRHG--IVDVSYHDTTHFPLTWVL---TPGRELAIKLEHRVVD 2541

Query: 402  YLPAAEIGERMLTVLRQL---PDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWE 458
               A E+ E+++TVLR +   PD   G  D +     A+L+       R  P    T+ E
Sbjct: 2542 DARATEMVEQLVTVLRTIAAEPDTAVGAVDLIGADRRAQLERRWSSTER--PLEPVTIAE 2599

Query: 459  MFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS 518
            +  R+ +                TY E   R  + A  L   G  PET VAL LPRS   
Sbjct: 2600 LLARRAEQNPDDVALVFG-AQSVTYREFDDRVSQFARHLRARGAAPETFVALALPRSIDM 2658

Query: 519  XXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTA----VPTLA 574
                         YLP+++ LP  R+ +I+  A P L +T  D ++L+G A       +A
Sbjct: 2659 VVALFAVLRAGAAYLPLELDLPIDRLRTIIDNAEPVLLVTTTDRTELIGHARARGADVIA 2718

Query: 575  LDDPAAVESISRRSAAAPTVDR---------RPEQSAYVIFTSGSTGEPKGVVGTNAAVL 625
            LDD     +++   A   T            R    AY+I+TSGSTG PKGV+   A + 
Sbjct: 2719 LDDAETAATLADTPAHPLTAGELGAFASDSTRLNHPAYLIYTSGSTGRPKGVLTGYAGLT 2778

Query: 626  SYFADHAERVYXXXXXXXXXXXXXX--HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRD 683
            + + +H E ++                H  S SFD SW+ +  L++GH++H+ D E  RD
Sbjct: 2779 NMYFNHREAIFAPTVARAGSAEQLRIAHTVSFSFDMSWEELFWLVEGHQVHVCDEELRRD 2838

Query: 684  ADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLD---HNLSVLALGGEAINTGLWDQLRGL 740
            A  LV      +ID+I+ TP+    L  AGLLD   H   ++ LGGEA+  G+W  LR  
Sbjct: 2839 APALVAYCHRHRIDVINVTPTYAHHLFDAGLLDDGAHTPPLVLLGGEAVGDGVWSALRDH 2898

Query: 741  SQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYL 800
               A YN YGPTE T+        D   PT+G     T GY+ D+ALR VPDG VGELY+
Sbjct: 2899 PDSAGYNLYGPTEYTINTLGGGTDDSDTPTVGQPIWNTRGYILDAALRPVPDGAVGELYI 2958

Query: 801  SGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGG--YAYVGRADTQVKI 858
            +G  LA GY  R G+TAA  VADP  PG RMYRTGDLVRR         Y+GR D QVKI
Sbjct: 2959 AGTGLALGYHRRAGLTAATMVADPYVPGGRMYRTGDLVRRRPGSAELLDYLGRVDDQVKI 3018

Query: 859  RGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRT----SLVGFVV---WQDNMHEDLIKL 911
            RGYRVE+GEIE+ L    GV   AV V R         +L  +V+   W       +  L
Sbjct: 3019 RGYRVELGEIESVLTRADGVARCAV-VARATGANPPVKTLAAYVIPDRWPAEDAAFITGL 3077

Query: 912  RAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTE 971
            R  L   LP YMVP R   +  LP+  NGKLD  AL         + + GT  +  TD E
Sbjct: 3078 RDHLARVLPGYMVPTRYGIVDTLPLTINGKLDVAALPE-----PIAATSGTGRTPRTDRE 3132

Query: 972  RVLCELFEEQLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQL 1030
              L E+    L      +DDD F  G DSI +IS+  +AR+ GL + PR V    TI  L
Sbjct: 3133 ATLLEIVASVLGIDGIGVDDDFFTLGGDSISSISVCGRARKAGLNITPRDVFRRRTIAAL 3192

Query: 1031 GAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGN-YRRFTHTVLLRLPSGIDRSSIEL 1089
             A+ D     +  P D   GA+   PM++   +       F   ++L  P+GI    ++ 
Sbjct: 3193 AASADTTQTPESGP-DTGTGAITATPMLAETAQANTPLTNFYQAMVLATPAGITAHEVQR 3251

Query: 1090 MLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAA 1149
            +LQ ++D H  LR+ L  T  G  L   +  A     V +     +  + E A+A A   
Sbjct: 3252 VLQTVVDAHAMLRARLVTTATGWTLTVPDQTAAIGLTVRSGALTSDCVEAEKAAAAA--- 3308

Query: 1150 RVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRS 1209
                 ++DP AG MVRA+WF   E     +  LLL  HHL +D VSW I+  DL+ AW  
Sbjct: 3309 -----ELDPRAGNMVRAVWFDAPE----ASGQLLLVIHHLVIDGVSWRILSEDLSRAWND 3359

Query: 1210 LQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRD 1269
            L AG         TS+  W   +  R       D+ +YWA ++  PDP LG R PDP  D
Sbjct: 3360 LAAGRDVAADAVPTSFHTWANALAQRT----FDDESEYWADVLATPDPDLGSRPPDPAID 3415

Query: 1270 TWSTLQLTRAAIPVDVTERVLGAV--RRDQGVRELLLAATAMAVASWRRVRAQDPAAGVL 1327
            T  T++     +  DVTE +L +V      GV ++LL   A+A+A WR  R        +
Sbjct: 3416 TADTVRSHEVTLASDVTEALLTSVPAAMHGGVNDVLLTGLAVALAQWRADRGHSQNTAAV 3475

Query: 1328 VALEGHGRADAVL--DTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSV 1385
            ++LEGHGR   ++  D D + TVGWFT+ +PVR+  G    D  ++    +AA     +V
Sbjct: 3476 ISLEGHGRESDLVAADLDLSRTVGWFTSIYPVRIDPGPLEWDTVRSAGAELAA--AAKAV 3533

Query: 1386 VSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYL 1445
               L A+PN GL YG+LR++ G    +D   PQI F+YLGR   G   D  W  + G  +
Sbjct: 3534 KEQLRAVPNRGLGYGVLRHLHGA---LDGTPPQILFNYLGRFTGGSGND--WRPVAG--I 3586

Query: 1446 DALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIA 1505
             AL    +P  P   +L ++       +GT L     W   + +  D+  L  +W   + 
Sbjct: 3587 GALTEGVDPSNP-AMSLEINALAEERPDGTVLSMTLAWPGGLLDADDVSELGSMWADVLV 3645

Query: 1506 AL 1507
            AL
Sbjct: 3646 AL 3647



 Score =  632 bits (1631), Expect = e-179
 Identities = 502/1541 (32%), Positives = 731/1541 (47%), Gaps = 96/1541 (6%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            ++E+VL L PLQEG++      +   D Y +Q +  + GPVD E+LR S   ++ RH  L
Sbjct: 3679 EVEEVLPLLPLQEGMYFHSMFGDPATDTYRVQQIAQLSGPVDPEVLRTSLTVVMRRHQAL 3738

Query: 67   RAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLS 126
            RA+F +    +  Q++   + +P    V    + +SIA  E  RPF+L+  P +R +++ 
Sbjct: 3739 RASFNELTDGRVAQVI--WSDVPVQLTVVDTDDLESIAAEELARPFNLAEAPLVRYMLVR 3796

Query: 127  VPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX--YIVWLAK 184
            + G+   R++ T HHI+ DGWS  V F +++                      +I  +  
Sbjct: 3797 L-GDDDHRLVQTMHHIIADGWSYPVLFGDIVDHYNAAIGVGSAPQPITVTLRDHIETVTD 3855

Query: 185  QDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRHGLTL 244
            +DR AA   W   L G     +V     A   +       L +A TA + + A  HG+T+
Sbjct: 3856 RDRGAARQAWEQALAGAEPTALVPRPDGAPVGEHRSVVRRLDSARTAAVGRAARVHGVTV 3915

Query: 245  NTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEAV 304
             T +  AW ++L RL  R  VVFG+ VSGR   L G E++VGL IN +PV         +
Sbjct: 3916 GTVLHGAWGLMLGRLLGRNRVVFGSTVSGRGGDLAGTESIVGLLINTIPVPMSWEPHATL 3975

Query: 305  VAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDGAQ 364
             +    +Q Q SA+ D   + L+E+ R  G    FD++ + EN P   +    T P    
Sbjct: 3976 ASALIDLQDQQSALLDAQQMGLAELARLAGVREFFDTMVIVENFPSTSSAE-HTDPRAVA 4034

Query: 365  FLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPA--AEIGERMLTVLRQLPDI 422
            F         HYP++ V++                 P      AE  ER+LT   + PD+
Sbjct: 4035 FRGFTGTDSPHYPVSFVAYADDQLTVEIKYDAGVVTPEQAERYAERVERILTAFAETPDL 4094

Query: 423  GDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHT 482
                   +D+RT AE +     A+R  P    T+   F  +V               R T
Sbjct: 4095 ---PVSRIDLRTNAERQFTAGHASRPGP--GRTLGASF-AEVAATYPDAVAVSCGDTRLT 4148

Query: 483  YAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSA 542
            Y EL  RA  +A  LAE GVG E+ VA+ LPRS                Y+P+D+  P+A
Sbjct: 4149 YRELDDRAAAVAATLAERGVGAESRVAIALPRSADLIVAVLAVIKAGGTYVPIDIGAPAA 4208

Query: 543  RVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSA 602
            RV+ I+  ++P   +T+        T VP + L + A     +     APTV   P+ +A
Sbjct: 4209 RVQHILADSAPVCLLTDTAER---FTGVPHVILAEAAQ----NPARPQAPTVS--PDHAA 4259

Query: 603  YVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS-W 661
            YVI+TSGSTG PKGV  T+  V + FA     +Y                 S +FD S W
Sbjct: 4260 YVIYTSGSTGVPKGVEVTHRNVAALFAGTTSGLYDFGPDDVWTMFH-----SAAFDFSVW 4314

Query: 662  QPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQ-LSAAGLLDHNLS 720
            +    LL G  + + + +  RD +R V+ +A  ++ +++ TPS F   L A   L   L+
Sbjct: 4315 ELWGPLLHGGRLVVVEHDVARDPERFVDLLARERVTVLNQTPSAFYPLLEADARLRRQLA 4374

Query: 721  V--LALGGEAINT---GLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTAN 775
            +  +  GGEA++      W          + N YG TE  V               G+  
Sbjct: 4375 LRYVIFGGEALDVRRLAPWYANHESHSPRLVNMYGITETCVHVSHRALDTADTGAAGSVI 4434

Query: 776  AGTFG----YVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQR 830
             G       ++ D+ L+ VP GVVGE+Y++G Q+ARGY GRPG+TA RFVA+P    G+R
Sbjct: 4435 GGPLPGLRIHLLDNNLQPVPAGVVGEMYIAGGQVARGYTGRPGLTATRFVANPFDGAGER 4494

Query: 831  MYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQD 890
            +YR+GDL      G   Y+GR+D QVK+RGYR+E+GE+EAAL   PGV +AA  V R  D
Sbjct: 4495 LYRSGDLAMWTDAGELVYLGRSDAQVKVRGYRIELGEVEAALVTLPGVTNAAADV-RHDD 4553

Query: 891  --RTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
              R  L+G+VV       D+  LR+ L ERLP YMVP+ ++ L  LP+  NGK     LD
Sbjct: 4554 TGRARLIGYVVGD---ALDIGALRSTLAERLPDYMVPSVLLRLDVLPLTVNGK-----LD 4605

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPHIDDDLFLFGMDSIVAISLVHK 1008
            R A      V    A  A T T  +L  L  E L     ++DD F  G DSI+AI LV++
Sbjct: 4606 RAALPDPEPVEQAPAPVAGTGTASLLAGLCTEILGTTVGVEDDFFTAGGDSIIAIQLVNR 4665

Query: 1009 ARRQGLRVDPRMVLTATTIRQLGAAID----AAVD-SQDAPADADYGAVRPLPMVSWLYE 1063
            ARR+G+R+ P+ V    T   L + +D    AA D + D  A  D G V   P+V  L E
Sbjct: 4666 ARREGVRITPQQVFVHRTPAALASVLDTGSVAAPDATPDEDAGPDLGEVMLTPIVQRLAE 4725

Query: 1064 Y-GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAV 1122
              G   RF  + LLR P+G   + +E  +  ++  HD LR  L      P L + E  A 
Sbjct: 4726 LGGTVTRFNQSELLRTPAGATVARLETAINAVIARHDALRIRLHR--PAPMLWSLETTAA 4783

Query: 1123 RAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWF-RGTEHRADPANI 1181
             A   +TRI      D++L + +A  +    D++DP  G +V A+WF RGT    D    
Sbjct: 4784 -APVSITRIDAHGFDDEQLRTVIATESDAAADRLDPENGVVVVAVWFDRGT----DTQGR 4838

Query: 1182 LLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQV 1241
            LLL  HHLAVD VSW I+L DLA A+R   +G      P  TS R++   +   A     
Sbjct: 4839 LLLVVHHLAVDGVSWRILLDDLAEAYRQALSGQRVAPAPVTTSLRQYARTVNENAQHSSR 4898

Query: 1242 QDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAV--RRDQGV 1299
              + ++W   V  P   L +   D    T    +     +  + T  +L  V    +  V
Sbjct: 4899 LTEFEHWTE-VLAPGGEL-VATADVVTLTVGATRDHEIRLSTEDTAPLLTTVPAAANADV 4956

Query: 1300 RELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRL 1359
             E L+AA  +AV+ WR  R +   A ++++LE HGR     D D + TVGWFT+  PVRL
Sbjct: 4957 TETLVAALHLAVSRWRAARGEAADAPLVLSLERHGRDGWPDDVDLSRTVGWFTSIAPVRL 5016

Query: 1360 GAGAAAVDIEQAERDPVAAQDLVH---SVVSHLEAIPNDGLDYGLLRYVD--GVAELVDA 1414
                           P   +DL++   +V   L A P+ GL +G LRY +    A L   
Sbjct: 5017 ---------------PAPGEDLLNTLKAVKESLRAAPDGGLGFGQLRYCNPRTSAVLARL 5061

Query: 1415 VDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEG 1474
              PQ+ F+YLGR       D  W+  + P +DAL  +P PDL   + + ++     T +G
Sbjct: 5062 GTPQLLFNYLGRWAADACDD--WA--SAPEVDALRTEPNPDLGTPYLVEVNAICDDTVDG 5117

Query: 1475 TQLIGNWRWSDAVFERSDIDHLTGLW---QRGIAALAAGLD 1512
             +L     ++D   +   +  L  LW    R + +LA G D
Sbjct: 5118 PRLRATLTYADGELDEPSVAELGELWVAALRELGSLATGGD 5158



 Score =  569 bits (1466), Expect = e-159
 Identities = 465/1413 (32%), Positives = 661/1413 (46%), Gaps = 111/1413 (7%)

Query: 1    VTAAAP-QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAM 59
            VT A P  +E +  LSPLQEG++   + A   V  Y +Q V D   PVD   LR +  A+
Sbjct: 5179 VTGAVPGNVETIWPLSPLQEGVYLQARYATAAV--YIVQNVFDFAEPVDTTALRTAYSAV 5236

Query: 60   LDRHPNLRAAFWDRDVPKPVQIV-------PVHAALPWSERVATPAEFDSIARSERRRPF 112
            + R+P LR+AFW  D+P+PV  +       P    L            + I   +R++ F
Sbjct: 5237 MARNPVLRSAFWADDLPQPVAAIVADPVCEPRVVDLGGLPATQVERRVEEITADDRQQTF 5296

Query: 113  DLSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLA---VXXXXXXXXXX 169
            DL+  P  R+ VL  P   + R+IF+ H +L+DGWS      EL A              
Sbjct: 5297 DLAAAPLARMTVLRTPD--RDRLIFSYHFLLLDGWSREQLLRELFAEYTAARGGAVAQLP 5354

Query: 170  XXXXXXXXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPG-KTELLLPAA 228
                    Y+ WLA+QDR  +   W + LR +  P ++  +A         + E LL  A
Sbjct: 5355 APTADFTDYLRWLARQDRDVSAREWSEALRDLEAPTLLVPDAVGTDPTLALRLEFLLSEA 5414

Query: 229  DTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLF 288
            DTA L   A   G+TLN  +  A A+VL+  T R DVVFG+ V+GRP  L G+++++GLF
Sbjct: 5415 DTAALTAAARSAGVTLNALISTALAMVLAYETGRDDVVFGSTVAGRPTDLDGIDSVIGLF 5474

Query: 289  INAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQR--EHGRGPLFDSLFVFE 346
            +N VP    ++    V      VQ     + D  YL L +IQR    G GPLFDSL+V +
Sbjct: 5475 LNTVPTRVRLAPHRTVADTMRAVQSDRLRLMDHEYLGLGDIQRAVSTGGGPLFDSLYVLQ 5534

Query: 347  NAPIDDAIRPATTPDGAQFLPVEMESL--THYPLTVVSHLRXXXXXXXXXXXXXXXPYLP 404
            N   DD      T   AQ+  V  +S+  +HYPLT V+                  P + 
Sbjct: 5535 NFLDDDTF----TDMEAQYGIVGHDSIDASHYPLTWVAS-----PGRRLWMKLEYRPDVV 5585

Query: 405  AAEIGERMLTVLRQ-LPDIGDGTPDD-----LDIRTAAELKAHGLLAARSAPTFDTTVWE 458
              +  + +L  LRQ L  +G G         L +   A+ K     A        + +  
Sbjct: 5586 ERDRAQGLLDRLRQVLLQVGTGVERPSAALTLPLPAEADHKRTRDAATEHDLPHASVLDL 5645

Query: 459  MFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS 518
            + ER VQ             V   YAEL AR  RLA  L   G+GPE  VAL +PRS  +
Sbjct: 5646 LAERAVQSGDLTALVCGGEFV--DYAELLARVNRLAWVLRSRGIGPEDTVALAVPRSIDA 5703

Query: 519  XXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVG--TAVPTLALD 576
                         YLP+++  P  R+  ++  A P   +     +Q +    + P   LD
Sbjct: 5704 VVALFAVLRAGAAYLPLELDYPDERLAVMLGDAEPVRVLVTGATAQRIARVASAPLTVLD 5763

Query: 577  DPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVY 636
             P   + ++R  +        P+Q AYVI+TSGSTG+PKGVV  +  + +   +H E ++
Sbjct: 5764 APDTCDELARARSDWDGYSPHPDQPAYVIYTSGSTGKPKGVVTPHRGLTNMHLNHREAIF 5823

Query: 637  XXXXXXXXXXXXXX-HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQ 695
                           H  S SFD SW+ ++ L++GHE+H+ D    RDA  LV      +
Sbjct: 5824 APTIARAHGRRLKIAHTVSFSFDMSWEELLWLIEGHEVHICDEVLRRDATSLVRYCHDHR 5883

Query: 696  IDMIDTTPSMFVQLSAAGLLD---HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPT 752
            ID+I+ TP+    L   GLL+   H   ++ LGGEA++T +W++LR   +   YN YGPT
Sbjct: 5884 IDVINVTPTYAALLFEEGLLEQAGHPPVLVLLGGEAVSTTVWNRLRDSERWYGYNLYGPT 5943

Query: 753  EMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGR 812
            E T+        D   PT+GT    T  ++ D+ LR VPDGV GELY++GA LARGY+G+
Sbjct: 5944 EYTINTLGGGTDDSATPTVGTPIWNTRAHILDNWLRPVPDGVPGELYIAGAGLARGYLGQ 6003

Query: 813  PGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
            PG+TA+RFVA+P  PG RMYRTGDLV R +     ++GR D QVKIRGYRVE+G+IEAAL
Sbjct: 6004 PGLTASRFVANPFEPG-RMYRTGDLVVRRADDNIDFLGRTDDQVKIRGYRVELGDIEAAL 6062

Query: 873  RGQPGVHDAAVSVLRQQDRTS-LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTL 931
               PGV  AAV        +S LV +VV      + L  LR  LT  LP+YMVP  + TL
Sbjct: 6063 VSHPGVSQAAVIARPDTAGSSRLVAYVVPTTENPDVLDDLRMHLTATLPAYMVPTAMATL 6122

Query: 932  PRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP----H 987
              +P+  NGKLD  AL     D       G   +     E  LC +F E L         
Sbjct: 6123 TEIPLTDNGKLDTRAL----PDVAPIGRHGAGRAPQGAVEATLCSVFAEVLGLDGPDGLS 6178

Query: 988  IDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAID----------- 1035
            +DDD F  G  S++ I L+ + R + G  +    V  + T+  L   +            
Sbjct: 6179 VDDDFFDLGGHSLLTIRLISRIRSELGAELTLGDVFNSRTVAALARHVTADEGDNRRPRL 6238

Query: 1036 -AAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLL 1094
             A    Q  PA     A R + M+  L E G+   + + ++ R+   +D  ++   L  +
Sbjct: 6239 VAGPRPQHIPASP---AQRRMLMLDRLGETGS--AYNYPLVFRVRGALDVDALRDALTAV 6293

Query: 1095 LDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLP--EGSDDELASAVAHAARVV 1152
            +D H+ LR++  +              V  + +L R T P    SD         A  +V
Sbjct: 6294 VDRHEALRTVFDDRD-----------GVYHQRILPRGTQPPLHVSDCPEHELATRADALV 6342

Query: 1153 TDQIDPSAGAMVRAIWFR-GTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQ 1211
              + D +    +R    R G E   D   ++LL  HH+A+D  S  + L DL AA+ + +
Sbjct: 6343 EHRFDLTGEIPLRVDVLRSGPE---DHTVVMLL--HHIAIDEWSDAVFLADLDAAYAAHR 6397

Query: 1212 AGTPPKILPEFTSYRRWCELMWHRASAPQVQD-QRDYW-AALVREPDP-ALGLRYPDPTR 1268
            AGT   +      Y      +W R    Q+ D QR++W  AL   PD  AL    P P R
Sbjct: 6398 AGTAAPLPEPVVQYAD--HTLWQRDVLAQLGDRQREFWRTALAGAPDELALPADRPRPAR 6455

Query: 1269 DTWSTLQLTRAAIPVDVTERVLGAVRR---DQGVRELLLAATAMAVASWRRVRAQDPAAG 1325
             T +        + V++T     A+RR   D+ V  L++   A+AV   R     D   G
Sbjct: 6456 PTGA-----GGTLDVEITAETASALRRLAADKQVSMLMVLHAAVAVLIHRLGAGDDIVVG 6510

Query: 1326 VLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
              VA    GR DA LD    + VG F N   +R
Sbjct: 6511 TPVA----GRDDAALD----DVVGLFVNTVVLR 6535



 Score =  404 bits (1038), Expect = e-110
 Identities = 349/1119 (31%), Positives = 496/1119 (44%), Gaps = 76/1119 (6%)

Query: 426  TPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAE 485
            T D LDI    EL  +      S P   +TV  +F  Q                R TY  
Sbjct: 2    TADSLDIAELLELWNN-----HSTPERTSTVPTLFAAQCALTPDEVAVVDGER-RLTYRH 55

Query: 486  LHARACRLAGEL-AEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARV 544
            L     +LA  +    G GPE +VA+ +PRS                ++P+D + P+ R 
Sbjct: 56   LETHVAQLAHAVRVAAGEGPEPIVAIGVPRSAEMVVCVLAAMMAGVAFVPLDPSWPAHRR 115

Query: 545  ESIVRQASP-ALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSAY 603
              ++  +   A  IT  D S      VP L +D        +  S   P  D  P Q AY
Sbjct: 116  RQVLADSGAVATFITREDESDW---GVPGLRVD--LGAWQFTAESPVLPQADVHPAQLAY 170

Query: 604  VIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQP 663
            VIFTSGSTG+PKG +  + A+        +R +                  LSFD S   
Sbjct: 171  VIFTSGSTGKPKGAMIRHDAIAERL--QWQRDHILHFGKHDHTDASLFKAPLSFDISVNE 228

Query: 664  -MVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMF---VQLSAAGLLDHNL 719
             ++ L+ G  + +   +  +D + L+E I   Q+  +    SM    ++L      D   
Sbjct: 229  ILLPLVSGGRVVVAVPDGEKDPEYLLELIRTEQVTFVYLVSSMLDTLLELDRLATADGAP 288

Query: 720  SVLA------LGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRK---PT 770
            S LA       GGE +  GL+ + R      +Y+ YGP E T+       +D  +    +
Sbjct: 289  SSLASLRHVWCGGEVLTPGLFARFRKQLTTTLYHGYGPAEATIGVSHVIYRDTAERIATS 348

Query: 771  IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRP-GQ 829
            IG  N  T  YV D  LR VP GV GELY +G  L RGYV  P +TA+RFVA+P    G 
Sbjct: 349  IGRPNPHTQLYVLDEYLRPVPPGVGGELYAAGFLLGRGYVNAPSLTASRFVANPFDGNGS 408

Query: 830  RMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQ 889
            RMYRTGDL R    G   ++GRAD QVKI G RVE+ EIE+ L   P V  A V V RQ 
Sbjct: 409  RMYRTGDLARWTEDGSLEFLGRADNQVKIGGRRVELEEIESQLADHPAVRHAVVDVHRQG 468

Query: 890  DRTSLVGFVVWQDNMHEDL---IKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHA 946
                LVG++V  D +  D     ++      RLP YMVP   V L ++P+ ANGK D  A
Sbjct: 469  GADVLVGYLVAADGVRNDAAWHAEVADWARTRLPEYMVPKAFVALDQVPLTANGKTDRRA 528

Query: 947  LDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSIVAISL 1005
            L   A D   S   GT     T  E VLC++F + L+     +D+D F  G DSIVAI +
Sbjct: 529  LP--APDLERS---GTVKPPRTPRETVLCQVFADALDIDAVGVDEDFFALGGDSIVAIRV 583

Query: 1006 VHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYG 1065
            V + R  G  + PR +    T+  L   +  +      PA    GA  P P++ WL E G
Sbjct: 584  VSRLRAAGYTLRPRDMFAHRTVEALAPLLGDSDVRDTGPAVDPTGAATPTPILRWLDEVG 643

Query: 1066 N----YRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAA 1121
                    F   + L  P+  D +++   +   +  H  L +     P G    T     
Sbjct: 644  TAGSVLNGFHQGMSLVTPADADENTLRAAIAATVRRHHVLWA-----PPGR---TASDID 695

Query: 1122 VRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANI 1181
            +      TR+ + + SD       A A +V    +     A +   W R    R      
Sbjct: 696  IPGTPPETRLLIADASD----GIPAQAEKVARQLVSLLDTARIAFGWIR----RPAAPGR 747

Query: 1182 LLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQV 1241
            L++ A H  +D VS  I+  D+A A+  +  G   ++    TS+R W + +   A+A   
Sbjct: 748  LVVIADHTVIDGVSLRILAEDIATAYGLIAEGRAVELPTPHTSWRAWAQRLADTAAAGGF 807

Query: 1242 QDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAV--RRDQGV 1299
                ++W  +    +   G R  DP  DT +T       +P  VT+ +L  V  R    V
Sbjct: 808  DADLEHWQQVCATTETPWGDRALDPAIDTVATESRLTVELPSAVTDAILTTVPDRIHGHV 867

Query: 1300 RELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDT-----TNTVGWFTNA 1354
             + L+AA  +A+  W   R    A  +LV +EGHGR   ++D+DT     +NTVGWFT  
Sbjct: 868  NDALVAALYLALRRWLHTRGVG-ADTLLVEMEGHGREGHLVDSDTAGLDLSNTVGWFTTL 926

Query: 1355 FPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV-DGVAELVD 1413
            +PV L    A  D + A          V SV   L ++P+ G  YG LRY+ DG + L  
Sbjct: 927  YPVAL--RDAEFDWQAAVSGGPQLGAAVRSVKDQLRSVPSHGFSYGALRYLRDGTSGLEA 984

Query: 1414 AVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAE 1473
            A  PQ+ F+YLGR    G AD+PW+L       A+  D +P +PL   L ++     TA+
Sbjct: 985  A--PQVLFNYLGRF---GTADRPWALAND--TTAVLEDRDPGMPLPRLLEVNAEAVTTAD 1037

Query: 1474 GTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD 1512
            G+ L   + W        D+  L G+W   + A+A+  D
Sbjct: 1038 GSVLRATFSWPAHAVAEVDVRTLAGMWTDLLTAIASSDD 1076



 Score =  390 bits (1003), Expect = e-106
 Identities = 420/1414 (29%), Positives = 592/1414 (41%), Gaps = 137/1414 (9%)

Query: 6    PQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPN 65
            P + D+L L+P Q+G++  H       D Y +Q +VDI GP+D E  +R+ +++  RH  
Sbjct: 1103 PGLTDLLPLTPTQQGIY-FHSTFSRDRDPYVVQQIVDITGPLDTERFQRATESVAARHRA 1161

Query: 66   LRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSI-----ARSERRRPFDLSRGPAL 120
            L A F       PV +     A  +    A  A   S      AR ER R FDL+  P  
Sbjct: 1162 LGAVFTTLSDGTPVAVHAATVAPDFDVLDARHAADPSTVVAQRARWERERRFDLAAAPLT 1221

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIV 180
            R  ++    +    MI T HHI+ DGWS+ +   +LL                    ++ 
Sbjct: 1222 RYTLVRRRDDL-HTMIETVHHIVADGWSVPIVLDDLLTAYAGDDFDGPAPEFAR---FVD 1277

Query: 181  WLAKQDRSAALAGWMDYLRGVSEPLMVAYE-----ATAGQSKPGKTELLLPAADTARLRQ 235
            WL ++D  +  A W   L  ++EP  +A        T G     +T  L   +  A    
Sbjct: 1278 WLEQRDTDSDRAAWAPALEDITEPTRLAAADGARGRTTGSGFGTRTVTLQSRSAVADAAN 1337

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
             A    +T+ T +  AW + L RLT R DVVFGTVVSGR   + G+E+MVGL +N VPV 
Sbjct: 1338 GAA---VTVGTLLHTAWGLALGRLTGRDDVVFGTVVSGRGADVHGIESMVGLLVNTVPVR 1394

Query: 296  HYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIR 355
               S  +       ++    S + +  +L L+E  R  G G LFD+L V EN       R
Sbjct: 1395 VAWSADDTGADVAGRLAAVESTLLEHHHLPLTEAHRLAGVGELFDTLVVIENLGATTHTR 1454

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGE--RML 413
               T        + +    HYPLT++  +R                 L    +     +L
Sbjct: 1455 GDLTLGD-----IGVIEAPHYPLTLMISVRDTITVTVTNDREHVSDVLADTAVAAFTEVL 1509

Query: 414  TVLRQLPDIGDG-----TPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXX 468
            T L   P +  G      P      T A      L+AA  A   D     + E +     
Sbjct: 1510 TALTADPGVSPGDIALPAPQATAPPTQAPQTVTDLIAAAIAEHRDDIALVVGETE----- 1564

Query: 469  XXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXX 528
                         TY +L ARA  LA  LAE GV    +VAL   RS             
Sbjct: 1565 ------------WTYGQLGARAGELAAALAEAGVRRGDIVALATARSADLVAAIWAIIAA 1612

Query: 529  XXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRS 588
               YLPVD+  P  R+E ++R A P   I +      VG  V + AL     V S +   
Sbjct: 1613 GAAYLPVDLAYPRTRIEYMLRHARPTAVIADG-----VGAHVVSGALPADTIVVSTTATH 1667

Query: 589  AAAP--TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXX 646
            AA P   V      +  V++TSGSTGEPK VVGT+AA+ +  A   E             
Sbjct: 1668 AAVPFTPVPVDGADAVSVLYTSGSTGEPKAVVGTHAALANRLAWAVEA---------WPA 1718

Query: 647  XXXXHAWSLSF-DASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSM 705
                    LSF D + + + GL  G    L   E  RD  RL + +A   ++ +   PS+
Sbjct: 1719 ATRIAKSPLSFIDGTTELLAGLAAGARTVLAGDETARDGRRLAQLVAAHGVEQLLAVPSL 1778

Query: 706  FVQLSAAGLLD-HNLSVLALGGEAINTGLWDQLRGLSQMA-VYNCYGPTEMTVEXXXXXX 763
               L+     D   L+   + GEA+       LR     A + N YG +E+  +      
Sbjct: 1779 AAVLADERTEDVAELNRWIVSGEALEPRHLHALRTACPTAEIVNSYGSSEVAGDVLAGVQ 1838

Query: 764  KDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVAD 823
             D    T+G A  G    + DS LR +P GV+GE+Y++G QLARGY+GRPG TA RFVA 
Sbjct: 1839 DD-AGITLGAAVPGAGIRILDSRLRQLPAGVIGEIYVTGGQLARGYLGRPGQTATRFVAA 1897

Query: 824  PLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAV 883
            P   G+RMYRTGDL   L  G   + GRAD Q+KI G+RVE GEIE+ L  QPGV +AAV
Sbjct: 1898 P--GGERMYRTGDLGALLPGGRVVFAGRADDQLKINGHRVEPGEIESVLARQPGVREAAV 1955

Query: 884  SVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLD 943
                    T L  FVV + +       L   ++  LP ++VP+ +  +  +P+  NGK D
Sbjct: 1956 I----GTGTQLAAFVVLESDA-PGAGDLLTAVSAELPGHLVPSSLRPVDAIPLLPNGKRD 2010

Query: 944  GHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIVA 1002
             +AL  L    +   S GTA   + D ER + ++    L   P   DDD F  G DSI A
Sbjct: 2011 NNALRSL---LVPGESTGTA--PTNDVERAVLDVMTGVLGRDPLGADDDFFAVGGDSISA 2065

Query: 1003 ISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPM-VSWL 1061
            I +  +  R G  +    V    T   + A +D         A   +  VR  P  +  +
Sbjct: 2066 IRVTSRLARAGYHIATEDVFRGRTAAGVAALVDTVESLAHDAAIEPFATVRLSPQTIDRI 2125

Query: 1062 YEYGNYRRFTHTVLLRL------------PSGIDRSSIELMLQLLLDG-HDTLRSILTET 1108
             E G          L+L            P+ I ++  E   ++ +D       ++L   
Sbjct: 2126 RESGQVEDIWAMSPLQLGVYYQSTLADAGPTYIAQNVFEFDRRIDVDAMRRAFTALLRRH 2185

Query: 1109 PE---GPRLVTR---EPA-------AVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQ 1155
            P+   G R V     EPA        V   D  + +T+ + +D +  +A  H   V TD+
Sbjct: 2186 PQLRAGFRTVEHAEPEPAPDATPVVQVVVTDPPSDLTVVDLTDQDDPAAAQHI--VDTDR 2243

Query: 1156 ---IDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRS-LQ 1211
                D +   ++R    R    R    + +L T H L  D  S  ++L DL A + S  Q
Sbjct: 2244 TAPFDVATPPLLRLTVIRLPGGR----DRMLFTYHFLLFDGWSRELVLRDLFALYDSDAQ 2299

Query: 1212 AGTPPKILPEFTSYRRWCELMWHRASA-PQVQDQRDYWAAL---VREPDPALGLR--YPD 1265
             G    I P      R   L W      PQ    RD W  L   + EP  A G+   +PD
Sbjct: 2300 HGA---IAPHGDLVVR--HLQWLATDGDPQASGARDAWRDLLAGLTEPTLASGVSPDHPD 2354

Query: 1266 PTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAG 1325
                T     + R  +P DVT + L       G     +   A+A+ +       D   G
Sbjct: 2355 ARPGTEPGRIVVR--VPEDVTTQ-LHTCATAHGATLNSVVTAAVALVTGYHAGTTDVVIG 2411

Query: 1326 VLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRL 1359
              VA    GR   ++  D   T+G F N  PVR+
Sbjct: 2412 TTVA----GRPGHLVGID--ETIGLFLNTVPVRV 2439



 Score =  293 bits (751), Expect = 1e-76
 Identities = 317/1105 (28%), Positives = 466/1105 (42%), Gaps = 100/1105 (9%)

Query: 4    AAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRH 63
            A P+ + + A SP Q  +  L +L E G   Y+   V  + G +D++ LR +  A++DRH
Sbjct: 6240 AGPRPQHIPA-SPAQRRMLMLDRLGETG-SAYNYPLVFRVRGALDVDALRDALTAVVDRH 6297

Query: 64   PNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVV 123
              LR  F DRD     +I+P     P         E  + A +     FDL+    LRV 
Sbjct: 6298 EALRTVFDDRDGVYHQRILPRGTQPPLHVSDCPEHELATRADALVEHRFDLTGEIPLRVD 6357

Query: 124  VLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYI---V 180
            VL   G     ++   HHI +D WS AVF  +L A                   Y    +
Sbjct: 6358 VLR-SGPEDHTVVMLLHHIAIDEWSDAVFLADLDAAYAAHRAGTAAPLPEPVVQYADHTL 6416

Query: 181  W-------LAKQDRS---AALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADT 230
            W       L  + R     ALAG  D L   ++    A    AG    G  ++ + A   
Sbjct: 6417 WQRDVLAQLGDRQREFWRTALAGAPDELALPADRPRPARPTGAG----GTLDVEITAETA 6472

Query: 231  ARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFIN 290
            + LR+ A    +++   +  A AV++ RL    D+V GT V+GR D    ++ +VGLF+N
Sbjct: 6473 SALRRLAADKQVSMLMVLHAAVAVLIHRLGAGDDIVVGTPVAGRDDA--ALDDVVGLFVN 6530

Query: 291  AVPVVHYVSGTEAVVAQCTQVQRQSSAM---RDVSYLSLSEI---QREHGRGPLFDSLFV 344
             V +   ++G         +V+    A    +D+ +  L E     R  GR PLF+    
Sbjct: 6531 TVVLRADLAGNPTFTELLDRVRTADLAAFAHQDLPFDHLVEELNPPRVAGRNPLFNLFVG 6590

Query: 345  FENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLP 404
            +      D+       +  +  P    ++     T+V H                  Y  
Sbjct: 6591 YHLRSGTDSDMFGLPTEWTE--PAVSAAMFDLGFTLVDH-------GGDESASITAEYAA 6641

Query: 405  AAEIGERMLTVLRQLPDIGDGTPDDLDIRTAA-ELKAHG----LLAARSA---PTFDTTV 456
                   + T+ R+L  + D    D + R  A +L A G    L+   +A   P    T+
Sbjct: 6642 DLFDASTVHTLARRLVALLDHVVADAETRIGALDLLAPGEHDTLVVEHNATEHPLEPITL 6701

Query: 457  WEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSE 516
              +  RQ                  +Y +L   + RLA  L+  G  P TVV + LPRS 
Sbjct: 6702 GALVSRQATSTPHATALRYEES-ELSYRDLDGWSDRLAAHLSARGAAPGTVVGVSLPRSV 6760

Query: 517  RSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALD 576
                           +LP+D   P  R+E +V  A P                     LD
Sbjct: 6761 ELVVALVAVAKSGAAFLPLDPEYPRERLEYMVSDARPITV------------------LD 6802

Query: 577  DPAAVE-SISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERV 635
            DP AV  S        P +D  P   AYV++TSGSTG PKGV   +A +++  A   +  
Sbjct: 6803 DPDAVRRSRGEPDGELPRID--PAAWAYVLYTSGSTGRPKGVAVAHAGIVNRIAC-LQHA 6859

Query: 636  YXXXXXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIG 694
            Y                  +SFD S W+    L  G  + +      R+   L   IA  
Sbjct: 6860 YPLGTDDRMLVKTP-----ISFDTSVWEVFWPLSVGATLVVARPGGHREPAYLAAMIAEQ 6914

Query: 695  QIDMIDTTPSMF-VQLSAAGLLDHNLSVLALGGEAINTGLWDQL-RGLSQMAVYNCYGPT 752
             +  +D  PSM  V L        +L+ + +GGEA+ T L  +       + ++N YGPT
Sbjct: 6915 CVTAVDFVPSMLEVFLDEVAGTCASLTRVTVGGEALTTELAARFAEAFPGVPLHNLYGPT 6974

Query: 753  EMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGR 812
            E  V+       D     +G        YV D  L  VP G  GELYL+G QLA GY+ R
Sbjct: 6975 EAAVDVLGWTA-DGGPVALGVPGWNVRAYVLDDYLNPVPAGAPGELYLAGIQLADGYLHR 7033

Query: 813  PGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
              +TAARFVA P   G RMYRTGD+VR  + G   Y+GR+D Q+K+RG R+E GEIE  L
Sbjct: 7034 GALTAARFVASPFDQGARMYRTGDVVRWRADGQLEYLGRSDDQIKLRGVRIEPGEIETVL 7093

Query: 873  RGQPGVHDAAVSVLRQQDRTSLVGFVV---WQDNMHEDLIKLRAGLTERLPSYMVPARIV 929
               P V  ++V V+ +  R  L+ + V    + +  E   +LR      LPS+MVP+  V
Sbjct: 7094 ATHPAV--SSVRVIARGGR--LMAYYVPAGVEASAGELRDELREHAAAALPSHMVPSGFV 7149

Query: 930  TLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHI 988
             L   P+  +GKLD  AL   A     + +G    + +T+ +  LCELF + L   V  I
Sbjct: 7150 ALTEFPLTPSGKLDRRALPEFA----GATAGVPGRAPTTERQHRLCELFSDVLGLEVTGI 7205

Query: 989  DDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPA-- 1045
            DDD F+ G  S++ + L    RR+  + V    ++ + T+  +   +DAA  S D+ A  
Sbjct: 7206 DDDFFVLGGHSLLLVRLAAALRREFSVDVPVADLMVSPTVADIDQRLDAAGSSVDSLAPV 7265

Query: 1046 --------DADYGAVRPLPMVSWLY 1062
                    DA    V P   +SW +
Sbjct: 7266 LPFRASGTDAPLFCVHPASGLSWQF 7290


>tr|Q0S3K6|Q0S3K6_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal
             peptide synthetase; EC=5.1.1.13; EC=6.2.1.3;[Rhodococcus
             sp.]
          Length = 11258

 Score =  720 bits (1858), Expect = 0.0
 Identities = 516/1562 (33%), Positives = 754/1562 (48%), Gaps = 102/1562 (6%)

Query: 6     PQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPN 65
             P   DV  L+PLQ G+F    LAED VD+Y+ Q V+D  G VD   LR +A+A++ RH N
Sbjct: 9733  PDATDVWPLAPLQSGMFFHSVLAEDAVDVYTAQVVLDFQGIVDTGRLRGAAEALIARHAN 9792

Query: 66    LRAAFWDRDVPKPVQIVPVHAALPWSER-------VATPAEFDSIARSERRRPFDLSRGP 118
             LR AF   D    VQ+V    ALPW E                S+    R   FD+SR P
Sbjct: 9793  LRTAFVPDDSGTAVQVVVDRVALPWEELDLSGLSGAEREERMSSVLSEHRSARFDMSRPP 9852

Query: 119   ALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY 178
              +R +++   GE   R   + HHIL+DGWS+ +   +LL +                  +
Sbjct: 9853  LMRFLLIRT-GENSYRFSISNHHILLDGWSMPLLMKDLLVLYATRGDGSVLPRVRGYRDF 9911

Query: 179   IVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTA--RLRQW 236
             + WL+++D  A+ + W   L G+  P ++A  A + + +P   E  L   +     L + 
Sbjct: 9912  LGWLSERDTDASRSAWAHALAGLDGPTVLA-PAPSSEDRPEPAEFALHLGEVVSENLARI 9970

Query: 237   AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
             A   GLT+NT V  AW ++L+R+T   DVVFG  VSGRP ++ G+E+MVGLFIN +P+  
Sbjct: 9971  ARDRGLTMNTIVQAAWGLLLARMTASDDVVFGATVSGRPPEVAGIESMVGLFINTIPIRV 10030

Query: 297   YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDA-IR 355
              +   E+++    ++Q + S + D  ++ L EIQ+  G G LFD+L VFE+ P+D A + 
Sbjct: 10031 RIDPRESLLGLLERLQAEQSTLFDHHHIGLPEIQQIAGIGGLFDTLTVFESYPVDRAGLT 10090

Query: 356   PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLP-------AAEI 408
               +  DG +   V++   +HYPL++++                   YLP          +
Sbjct: 10091 EDSDIDGLRVAGVQISDASHYPLSLLAQ--------SDSELQLVLKYLPDVFGADTVERL 10142

Query: 409   GERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAA---RSAPTFDTTVWEMFERQVQ 465
             G R+  +L+ +         DLD+ T  E +   +L+          D +V  MF  QV 
Sbjct: 10143 GSRLNRILQTIAAGSSTLVGDLDLLTGDEREL--VLSGWNDSGHDVADESVVSMFGAQVA 10200

Query: 466   XXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXX 525
                          VR TYAE  AR  RLA  L   GVGP++VV + + RS          
Sbjct: 10201 RTPDRTAVVADH-VRLTYAEFDARVNRLARHLMSMGVGPDSVVGIAMRRSLDMVISLYAV 10259

Query: 526   XXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESIS 585
                   Y+P++   P+ R   +V  A P   ++ AD    +   VP   ++D    E   
Sbjct: 10260 HAAGGAYVPIEPEHPADRTSYVVDSAMPTCVLSLADDIANLDVDVPVYLVEDFDLSE--- 10316

Query: 586   RRSAAAPTVDR------RPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXX 639
                AA P  D       RP+  AY ++TSGSTG PKGV   +AA+ +  A      +   
Sbjct: 10317 --YAAGPVEDSERLAELRPDNLAYALYTSGSTGRPKGVAIPHAALANQLA------WMRD 10368

Query: 640   XXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDM 698
                             +FDAS W+  + L+ G  + +   +  RD + +   +    + +
Sbjct: 10369 VYGIGAQDVVLQKTPFTFDASVWELFLPLVVGGTLVIASPDGHRDPEYMAATVGTEAVTV 10428

Query: 699   IDTTPSMFVQLSAAGLLDH--NLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV 756
             I   PS+      A   D   +L ++  GGE +     +++ GL    + N YGPTE+T+
Sbjct: 10429 IQFVPSVLTMFLDAATADRSGSLRLVFAGGEPLPQSAAERVAGLGSAELVNLYGPTEVTI 10488

Query: 757   EXXXXXXKDYRKPT---IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRP 813
                    +     T   IG+    T  YV D+ L   P GV GELYL GAQLARGYV   
Sbjct: 10489 NSTAHVVEPSGTATIAPIGSPAWNTRAYVLDAHLNPAPIGVPGELYLDGAQLARGYVNSS 10548

Query: 814   GMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
              ++A RFVA+P    G RMYRTGDLVR   +G   +VGR D QVK+RG R+E+GE+E A 
Sbjct: 10549 ALSAERFVANPFDDSGARMYRTGDLVRWNENGVLEFVGRTDFQVKVRGLRIELGEVEEAF 10608

Query: 873   RGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLP 932
                  V  AAV V   +    LV +VV + +   D   L   + E LP YM+P  ++ L 
Sbjct: 10609 VRYRDVAQAAVIVHNSEVGARLVAYVVPKPDAALDAAALNGFVAESLPEYMIPDSLMVLA 10668

Query: 933   RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDD 991
              LP+  +GKLD  AL           S     + STDTER L  +F E L      IDD 
Sbjct: 10669 ELPLGTSGKLDRRAL-----PVPDFASAAEFRAPSTDTERALATVFGELLGRESVGIDDS 10723

Query: 992   LFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGA 1051
              F  G DSIV+I LV +AR  G+    R V    T+ +L A  D+   +  A  + + G 
Sbjct: 10724 FFELGGDSIVSIQLVARARSAGIHFTARDVFERRTVAELAAVADSGESAAAALQEYESGG 10783

Query: 1052  VRPLPMV----SWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTE 1107
             V  +P+       +   G++ RF   +LL LP+GI+R  +   +  ++D HD LRS L  
Sbjct: 10784 VGTVPLTPVARKMVERGGDFDRFVMPLLLTLPAGIEREQVIATIAAVVDKHDVLRSTLVT 10843

Query: 1108  TPEGPRLVTREPAAVRAEDVLTRITLPEGSD------DELASAVAHAARVVTDQIDPSAG 1161
             +  G  L      +V  +  + R+ +  G +      D +ASA   AA    D++DP  G
Sbjct: 10844 SGVGDALEIAPAGSVDIDATVQRVAIAAGDEPGSPEFDAVASAAFDAA---LDRLDPRTG 10900

Query: 1162  AMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPE 1221
             +M++ +WF   E  +D    LL+  HHL +D VSW I++ D A A   + AGT P + P 
Sbjct: 10901 SMLQFVWFDPAE--SDRRGRLLVVPHHLVIDSVSWRILVPDFATAGAQIAAGTSPSLEPV 10958

Query: 1222  FTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAI 1281
              TS RRW + +   A  P+   + + W  ++  PDP LG R  D   D  STL+ TR  +
Sbjct: 10959 GTSLRRWTDGLLEAAVKPERVAELEVWEHMLTGPDPLLGSRELDLGTDLVSTLERTRVDV 11018

Query: 1282  PVDVTERVLGAV--RRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADA- 1338
             P  VTE +LG      D  + ++L AA A+AV +WRR R  + A+  +V LEGHGR ++ 
Sbjct: 11019 PAPVTEALLGGTPGSLDGEIGDVLAAALALAVTAWRRDRGVE-ASSTVVTLEGHGREEST 11077

Query: 1339  VLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLD 1398
             V   D + TVGWFT  +P RL    A VDI  A R    A D V +V   L AIP+ G+ 
Sbjct: 11078 VPGADLSRTVGWFTTMYPARL--DLAGVDIADALRGGAGAADAVRAVRDQLSAIPDRGIG 11135

Query: 1399  YGLLRYV--DGVAELVDAVDPQIQFSYLGRLDLGGVADQ----PW-----SLLTGPYLDA 1447
             YGLLRY+  D  A + +  +PQI F+Y+GR+    V +      W     S ++G Y ++
Sbjct: 11136 YGLLRYLNPDTSAVMRNWSEPQIVFNYIGRVSAAEVPEAVRGLDWLPDFESSISGGYENS 11195

Query: 1448  LPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAAL 1507
                     +P +  L++   V  TAEG QL     +   +    ++D     W   + AL
Sbjct: 11196 A-------MPAQAVLDIQSVVSETAEGLQLSAFMSFPPDIISAPEVDRFGEFWVDALTAL 11248

Query: 1508  AA 1509
              A
Sbjct: 11249 VA 11250



 Score =  504 bits (1297), Expect = e-140
 Identities = 429/1414 (30%), Positives = 641/1414 (45%), Gaps = 121/1414 (8%)

Query: 6    PQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPN 65
            P + DV +L+PLQ GL     LA    D+Y+ Q V+D+ G VD + LRR+A++++ RHPN
Sbjct: 1549 PALGDVWSLAPLQVGLLFHASLAGTDTDVYTTQLVMDLGGSVDTDRLRRAAESLVARHPN 1608

Query: 66   LRAAFWDRDVPKPVQIVPVHAALPWSE-------RVATPAEFDSIARSERRRPFDLSRGP 118
            LR AF   D    +Q+V     +PW+             AE +++  + R   FD++  P
Sbjct: 1609 LRTAFVAGDDGAGMQVVVDRVDVPWTHVDLSAASESDRAAELEALMLANRTDRFDMTAPP 1668

Query: 119  ALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY 178
             +R +++   GE + R   T HHIL+DGWSL +   +LL +                  Y
Sbjct: 1669 LVRFLLVET-GEDRYRFAVTNHHILLDGWSLPILIQDLLTLYAVDGDELALPQPRPYRSY 1727

Query: 179  IVWLAKQDRSAALAGWMDYLRGVSEPLMVA--YEATAGQSKPGKTELLLPAADTARLRQW 236
            + WL+ QD    +A W   L G+ EP ++A  +  TA    PG+  + LP    A +   
Sbjct: 1728 LEWLSAQDPQVPVAAWTKALGGIEEPTLLAPAHAETAPTLTPGELVIDLPDDLLADMTAR 1787

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            +   G+T+NT V  AW +VL RLT R DVVFGT VSGRP Q+PG+E+M+GLFIN +PV  
Sbjct: 1788 SRELGVTMNTLVQAAWGIVLGRLTGRDDVVFGTTVSGRPPQVPGIESMLGLFINTLPVRV 1847

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPID-DAIR 355
             V   +AV     ++Q + + + D  ++ L++IQ+  G G LFD+L V+E+ P+D +A+ 
Sbjct: 1848 RVRAGDAVRTLLDRIQHEQTELLDHHHVGLTDIQQGLGLGALFDTLMVYESYPLDREALT 1907

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
             ++  +G + L V     THYPL +V+ +                      EI ER++ V
Sbjct: 1908 KSSDIEGLRVLDVTSNDATHYPLAIVA-MTDPRLHLTAKFLPEIFEAAEVEEIMERVVRV 1966

Query: 416  LRQLPDIGDGTPDDLDIRTAAE----LKAHG-----------LLAARSAPTFDTTVWEMF 460
            L  L    D    D+DI    E    L AHG           +LAA +A   + T     
Sbjct: 1967 LGALSGDVDTLVADIDILAPGERASLLAAHGTDAVVPLSLPEILAATAAENGERTA---- 2022

Query: 461  ERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXX 520
                             G   TYAEL AR+  LA  L + GVGPET VAL + RS  S  
Sbjct: 2023 -------------LVADGESLTYAELDARSNLLARVLVDRGVGPETSVALGMTRSLHSVI 2069

Query: 521  XXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAA 580
                       ++PVD   PS R+  +V  +   L +T A     + + V  LALD    
Sbjct: 2070 ATWAVAKAGGTFVPVDPRYPSERIAHMVADSGAILGLTVAAQRDTLPSDVEWLALDSSEC 2129

Query: 581  VESISRRSAAAPTVDRRP-----EQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERV 635
                + +SA   T   R      E  AY+I+TSG+TG PKGVV T+  + ++ A+     
Sbjct: 2130 DALCAPKSADPVTDSERTASVQLEHPAYMIYTSGTTGLPKGVVVTHTGLANFSAEQRTH- 2188

Query: 636  YXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQ 695
                           H  S SFDAS   ++         +    ++   + L   +A  +
Sbjct: 2189 -----YGVSPSARTLHFASPSFDASVLELLLAFGCGATMIVAPADLYGGEELRNFLADNE 2243

Query: 696  IDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMT 755
            +     TP+    +  AGL    L V+ +GGEA    L +  R      +YN YGPTE T
Sbjct: 2244 VTHAFVTPAALASVEPAGL--DRLEVVVVGGEACPPELVE--RWAPGRRMYNGYGPTEAT 2299

Query: 756  V-EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPG 814
            +            +  IG    G   YV D  LR VP GV GELY++G  LARGY  R G
Sbjct: 2300 IMSNVSNLLVPGSRVEIGGPVCGVTVYVLDELLRPVPVGVAGELYIAGPGLARGYHDRLG 2359

Query: 815  MTAARFVADPL-RPGQRMYRTGDLVR-RLSHG-----GYAYVGRADTQVKIRGYRVEVGE 867
            +TA RFVA+P    G RMYRTGD+VR  + HG     G  YVGR+D QVK+RG+R+E+GE
Sbjct: 2360 LTAERFVANPFGDSGSRMYRTGDVVRFVVDHGHRSGYGVEYVGRSDFQVKVRGFRIELGE 2419

Query: 868  IEAALRGQPGVHDAA-VSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPA 926
            I+A L   P +  AA +        T+LV +V+       D+ ++   + + LP++MVP+
Sbjct: 2420 IDAVLVKHPDLEFAATLGTSMPSGSTALVSYVLPTAGASVDVAEVTHFVGDMLPAHMVPS 2479

Query: 927  RIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AV 985
             +V L  +P+   GKLD  AL     DAL     G  +   T TE ++  +  + L  A 
Sbjct: 2480 SVVVLDEIPLTTAGKLDRKALPEPDFDALQ----GEMIEPRTPTEELVAGVLADVLGLAK 2535

Query: 986  PHIDDDLFLFGMDSIVAISLVHKAR-RQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAP 1044
              + +  F  G +S+VA   V +     G R+  R +  A T+ +L   +    +     
Sbjct: 2536 ISVAESFFDLGGNSLVATKAVARLNAAAGTRLGVRELFDAPTVERLAVKV---AEQAGTG 2592

Query: 1045 ADADYGAVRPLP---------MVSWLYEYGNYRRFTHTVLL--RLPSGIDRSSIELMLQL 1093
            +D      RP P            WL    +     + + L  RL   +D  ++   +  
Sbjct: 2593 SDRPVLVARPRPERVPLSMAQQSMWLMNRFDTASSAYNIPLAVRLSGSLDIDAMSSAVSD 2652

Query: 1094 LLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVT 1153
            +L  H++LR++  +  +GP         V  E V   +T    ++ EL +A+   A   T
Sbjct: 2653 VLARHESLRTVFPDAGDGP-----YQQIVDTEQVPFDLTPVPVTEAELHTALTEFA---T 2704

Query: 1154 DQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAG 1213
            +  D +    +R   F  +E       +L+L  HH+  D  S   +  D+  A+ +  AG
Sbjct: 2705 EGFDVTVAPPLRIRLFATSESEF----LLVLVVHHICADGASMSPLARDVMVAYSARTAG 2760

Query: 1214 TPPKILPEFTSYRRWCELMWHRASAPQVQD-------QRDYWA-ALVREPDPA-LGLRYP 1264
              P   P    Y  +   +W R       D       Q  +WA  L   P+   L L + 
Sbjct: 2761 AAPLWQPLPVQYPDFA--LWQREVLGDPADTQSLAGKQIAHWADTLAGAPELIDLPLDHA 2818

Query: 1265 DPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAA 1324
             P R +     +  A  P     R L AV +++G    ++   A+     R   + D   
Sbjct: 2819 RPARQSMRGDSIDFAITP--ELRRGLEAVGKERGASLFMVTHAALTTLLSRLSNSDDITV 2876

Query: 1325 GVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
            G  +A     R+D  LD    + VG F N   +R
Sbjct: 2877 GTPLA----ARSDQALD----DLVGMFVNTLVLR 2902



 Score =  500 bits (1288), Expect = e-139
 Identities = 430/1348 (31%), Positives = 606/1348 (44%), Gaps = 103/1348 (7%)

Query: 225  LPAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETM 284
            LP +    L +  G    +    V+ A+A  L+ +TDR DVV    VS R      +   
Sbjct: 205  LPESTATLLDEALGGSNASSAPIVVAAFAAYLAHMTDRTDVVLSLPVSARTTAT--LRRS 262

Query: 285  VGLFINAVPVVHYVSGTEAVVAQCTQVQRQ-SSAMRDVSYLSLSEIQREHG-----RGPL 338
             G+  N VP+   ++    V      VQ + + A+R   Y    +I+R+ G     RG  
Sbjct: 263  GGMVSNIVPLRLQITPEMTVPELVKSVQIELTGALRRQRYRH-EDIRRDAGAPQGQRGFF 321

Query: 339  FDSLFVFENAPIDDAIRPATTPDGAQFL---PVEMESLTHYPLTVVSHLRXXXXXXXXXX 395
              S+ +         I+  T       L   PVE  SL  Y     S +           
Sbjct: 322  GPSINIMM---FHSEIKLGTVTGHQNVLTTGPVEDLSLNIYQGVAGSKIHIDFEAN---- 374

Query: 396  XXXXXPYLPAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDT- 454
                 P L +A+  +R  +      +   G  DD  +   A +         +    D  
Sbjct: 375  -----PNLYSADELDRHHSRFFDFFERFLGAGDDASVSDLAAMSHEERGQVVTGWNGDVV 429

Query: 455  -----TVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVA 509
                 TV ++F+ QV             G   TYAE  AR  RLA  L   GVGPET VA
Sbjct: 430  TPPAGTVVDLFDAQV-GRTPDATALVFDGEELTYAEFDARVNRLARTLIGRGVGPETKVA 488

Query: 510  LVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTA 569
            L + RS  S             Y+P+D   P+ R   ++  A P   +T A    +    
Sbjct: 489  LAIRRSLDSMVAMYAVVKAGGAYVPLDSDHPAERTAYVLESARPLCILTVARDGLVFPAD 548

Query: 570  VPTLALDD------PAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAA 623
               L +D       PA       R+A     D RP   AYVI+TSGSTG PKGV  ++A+
Sbjct: 549  QDVLEIDALDLSGAPAGPIRDDERAA-----DLRPANPAYVIYTSGSTGRPKGVAVSHAS 603

Query: 624  VLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMR 682
            VL+     A R                     +FD S W+    L  G  + +   E  R
Sbjct: 604  VLNQVTWIASRY------GLDANDVVLQKTPTTFDVSVWELFAALASGSRLVIAAPEGHR 657

Query: 683  DADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDH--NLSVLALGGEAINTGLWDQLRGL 740
            D   L + IA  ++      PSM     A    +   +L V+ + GEA    +    R  
Sbjct: 658  DPAYLADVIAREKVTATSFVPSMLSVFVAEADREQLVSLRVVLVAGEAFPPAVAATFRAK 717

Query: 741  SQMAVYNCYGPTEMTVEXXXXXXKDYRKPTI--GTANAGTFGYVFDSALRMVPDGVVGEL 798
            S   ++N YGPTE TV             TI  GT    T  YV D  LR  P G  GEL
Sbjct: 718  SDAGLHNLYGPTEFTVHATAGEVDRETLHTIPIGTPVWNTEAYVLDGHLRPAPIGSAGEL 777

Query: 799  YLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVK 857
            YL+GAQ+ARGY GRP +TA RFVA+P    G R+YRTGDLV+    G   Y+GR D QVK
Sbjct: 778  YLAGAQVARGYEGRPELTAERFVANPFGAAGTRLYRTGDLVKWRVDGSIEYLGRTDFQVK 837

Query: 858  IRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTE 917
            +RG R+E+GEIEAA+   P V  +   V        LVG+VV +     D+  L   +  
Sbjct: 838  VRGLRIELGEIEAAMSSYPHVAQSVAVVHDSSLGQRLVGYVVPEPGSAVDVEDLTVHVGR 897

Query: 918  RLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCEL 977
             +PSYMVP  +V +  +PV A+GKLD  AL     +   +      V+  +  E  +  L
Sbjct: 898  AVPSYMVPDAVVVIAEMPVGASGKLDRKAL----PEPTFAAESSEYVAPRSTMEESIAGL 953

Query: 978  FEEQLNAVPHID--DDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAID 1035
            F E L  +P +   D  F  G DSIV+I LV +A+  G+    R V    T+  L     
Sbjct: 954  FAEVL-GLPRVSVGDSFFALGGDSIVSIQLVSRAKEAGVLFTARDVFERKTVASLAEVAK 1012

Query: 1036 AAVDS------QDAPADADYGAVRPLPMVSWLYEY-GNYRRFTHTVLLRLPSGIDRSSIE 1088
            +A +S      ++ P  A  G +   P+V W+ E  G++ RF+ ++LL LP  ++R  + 
Sbjct: 1013 SASESATVHVLEELPG-AGIGTMPLTPVVHWMTELGGDFHRFSQSILLALPPKVERDRLV 1071

Query: 1089 LMLQLLLDGHDTLRSIL--TETPEGPRLVTREPAAVRAEDVLTRITLPEG-SDDELASAV 1145
              L  ++D HD LRS L  T++P G  L      +V  + ++ R+   EG   D   +  
Sbjct: 1072 RTLAAVVDRHDALRSSLRRTDSPAGWSLEVAPIGSVDVDRLVDRVEFSEGPGTDSFEALA 1131

Query: 1146 AHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPA------------------NILLLTAH 1187
            AHA     D +DP+ G++VR +WF   E   D A                    LL+  H
Sbjct: 1132 AHALERTVDTLDPATGSVVRFVWFAPAEDAGDLAPRDGADADSGEGESTPQSGRLLVVIH 1191

Query: 1188 HLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDY 1247
            HLAVD VSW +++ D A+AW  + AG  P +    TS RRW   +   A + +   + D+
Sbjct: 1192 HLAVDGVSWRVLVPDFASAWAQIAAGADPLLPAVGTSVRRWAHGLADNARSARRVAELDH 1251

Query: 1248 WAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRR--DQGVRELLLA 1305
            W   +   DP +G R  D  RDT ST    R  +  DVT+ +L  V R    GV + LL 
Sbjct: 1252 WRTTLDGADPLIGSRALD-GRDTVSTTGRVRLEVSADVTDGLLTDVPRAFHGGVNDGLLT 1310

Query: 1306 ATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL-DTDTTNTVGWFTNAFPVRLGAGAA 1364
            A A+AVA+WR  R    ++  LV LEGHGR + VL   D + TVGWFT+ FPVRL   A 
Sbjct: 1311 ALALAVAAWRAERGVTESS-TLVHLEGHGREETVLPGADLSRTVGWFTSMFPVRL--SAP 1367

Query: 1365 AVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAV--DPQIQFS 1422
             VD+  A     AA   V SV   L  +P  G+ YG+LR+++     V A    PQI F+
Sbjct: 1368 GVDVRDALAGGAAAGRAVKSVKEQLARVPEHGIGYGMLRFLNAETRAVLAALPSPQISFN 1427

Query: 1423 YLGRLDLGGVADQPWSLLTGPYLDALPI--DPEPDLPLRFALNLSVFVGVTAEGTQ-LIG 1479
            YLGR+ +G + D   +    P  D + +      ++P+ FAL+++  + V  EG Q L  
Sbjct: 1428 YLGRVSVGEIPDAFRAAGWVPDTDTMELTGTRNSEMPVHFALDINAMI-VDVEGEQRLSA 1486

Query: 1480 NWRWSDAVFERSDIDHLTGLWQRGIAAL 1507
               +   V   +++  LTGLW R +  L
Sbjct: 1487 TVDFPQGVLADAEVGELTGLWARALEGL 1514



 Score =  444 bits (1143), Expect = e-122
 Identities = 343/1070 (32%), Positives = 514/1070 (48%), Gaps = 73/1070 (6%)

Query: 482  TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPS 541
            TY EL  R+ RLA  +   G+G +  VAL L RS  S             ++PVD + P 
Sbjct: 8660 TYRELDERSNRLARVMIGRGIGADDFVALALTRSVESILSIWAVAKTGAAFVPVDPSYPF 8719

Query: 542  ARVESIVRQASPALAITEADYSQLVGTAVPTLAL-DDPAAVESISRRSAAAPTVDR---- 596
             R+  +V  +   + +T   +   +   V  L L +D    +  S  S A    DR    
Sbjct: 8720 ERILHMVTDSRVEVGLTTGAHVGELPDTVRWLVLGEDEMDGDCASVSSEAVTDADRIRPT 8779

Query: 597  RPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLS 656
            R + +AYVI+TSGSTG PKGVV T+  + +   +  ER+               H  S S
Sbjct: 8780 RVDDAAYVIYTSGSTGLPKGVVVTHTGLANVTTEQVERL------RLTPQSRVLHFASPS 8833

Query: 657  FDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLD 716
            FDAS   ++  +      +  +  +   D L   +   ++     TP+    +  AGL  
Sbjct: 8834 FDASVFELLHAVAAASTMVIASGVVYGGDELARLLKKQKVTHAFITPAALTTVDPAGL-- 8891

Query: 717  HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKP-TIGTAN 775
              + VL++ GEA    L  +     +M  +N YGP+E T+           +P TIG   
Sbjct: 8892 DGIEVLSVAGEACPPELMQKWAPGRRM--FNLYGPSEATIWSTSSNPMKADQPVTIGGPT 8949

Query: 776  AGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLR-PGQRMYRT 834
             G    V DS L  VP GV GELY++G  +ARGY  R  +TA RFVA+P   PG+R+YRT
Sbjct: 8950 RGVDVVVLDSRLTPVPVGVAGELYVAGPSVARGYHNRFALTAERFVANPFGGPGERLYRT 9009

Query: 835  GDLVRRLSHGGYA-----YVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQ 889
            GD+VR +  G        YVGR+D QVK+RG+R+E+GEI+A L   P V D AV++   +
Sbjct: 9010 GDVVRWVHDGETGDLVLDYVGRSDFQVKVRGFRIELGEIDAELGSHPSV-DFAVTLGHHR 9068

Query: 890  D---RTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHA 946
            +   +T LV +V+       D+ +L A ++E LP YMVP+ I+ +  +P+   GKLD  A
Sbjct: 9069 ELTGQTVLVSYVMPAAGASIDVAELSAFVSETLPGYMVPSSIMAIDSVPLTPAGKLDRKA 9128

Query: 947  LDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIVAISL 1005
            L    E    S +     + ST  E+ + ++F + L      +DD  F  G DSIV+I L
Sbjct: 9129 LP---EPQFVSAASEYC-APSTPMEKAIADVFAQVLGVDRVSVDDSFFALGGDSIVSIQL 9184

Query: 1006 VHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD----ADYGAVRPLPMVSWL 1061
              +A+  G+    R V    T+  L      A D +    +       G++   P+  WL
Sbjct: 9185 TTRAKNAGVLFTARDVFERKTVSALADVAAWATDVESVKLEELPGGGVGSIPLTPIAHWL 9244

Query: 1062 YEY-GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEG---PRLVTR 1117
             E  G + +F+  VLL  P  + R  +   +  +L+ HD LRS LT   +      L T 
Sbjct: 9245 VETAGTFEKFSQAVLLTTPPAVTRDQLVATVDAVLERHDILRSRLTRAGDDWAFEALSTE 9304

Query: 1118 EPAAVRAEDVLTRITLPE--GSD--DELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTE 1173
            E  A  A+D++ RI   +  G+D  + LA A    A    +++DP++G M + +WF    
Sbjct: 9305 E--AFGADDLIERIEFTDKPGTDGFERLARAALDRA---AERLDPASGRMTQFVWFAPAA 9359

Query: 1174 HRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMW 1233
                 +  LL+ AHHL VD VSW ++L D A A   + AG P ++ P  +S R W   + 
Sbjct: 9360 SLPGQSGRLLVLAHHLVVDGVSWRVLLPDFATAGSQVTAGQPAQLEPVGSSVRAWAHGLV 9419

Query: 1234 HRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAV 1293
              A +P    + D+W  ++   DP +G R  DP RD  +            VT+ +L  +
Sbjct: 9420 EEAKSPHRVAELDFWRGMLAGTDPLIGKRAFDPARDVIARTDRLSMTFSTQVTQALLTTI 9479

Query: 1294 RR--DQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADA-VLDTDTTNTVGW 1350
             +  + GV + LLAA A+AVA WR +R       VL+ LEGHGR +A V   D + TVGW
Sbjct: 9480 PQSVNGGVNDGLLAALALAVARWRGLRNGTEDRSVLINLEGHGREEATVPGADLSRTVGW 9539

Query: 1351 FTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGV 1408
            FT+ +PVRL    A  D++ A     +    + +V   L A+P+ G+ YGLLRY+  +  
Sbjct: 9540 FTSLYPVRLDVSRA--DLDDAFDGGTSTGAALKAVKEQLLAVPDKGIGYGLLRYLNEETA 9597

Query: 1409 AELVDAVDPQIQFSYLGRL----------DLGGVADQPWSLLTGPYLDALPIDPEPDLPL 1458
            A L     PQI F+YLGR           DLG + D      +G +  A+    + D+  
Sbjct: 9598 AALASLPTPQIGFNYLGRAGSVDLPAEIRDLGWIPDSD----SGEFGGAM----DDDMVA 9649

Query: 1459 RFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
               L+++     TA G Q+     ++  + + +D+  L  LW     ALA
Sbjct: 9650 PAVLSINAVTSETASGPQIEAKIAFATEILDEADVWELAELWHAAATALA 9699



 Score =  356 bits (913), Expect = 2e-95
 Identities = 414/1569 (26%), Positives = 653/1569 (41%), Gaps = 141/1569 (8%)

Query: 2    TAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLD 61
            T  A    D + LS  Q+ ++ ++Q  +     Y++   V + G +D   L  +   +++
Sbjct: 6043 TLVARARPDRIPLSLAQQRMWFINQF-DPSSPAYNLPLAVRLTGSIDTAALNAAWADVVE 6101

Query: 62   RHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPA--EFDSIARSER--RRPFDLSRG 117
            RH +LR  F   D      ++P  AA   S+   TP   E D  AR        FD++  
Sbjct: 6102 RHESLRTVFPVGDEDAHQIVLP--AADVVSDLTPTPVADEQDLYARMRELGATGFDVTET 6159

Query: 118  PALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX 177
              +RV    V   T   ++   HHI  DG SLA  FT+++                    
Sbjct: 6160 VPVRVACFEV-NPTDHILMMVVHHISADGASLAPLFTDIMTAYAARAAGTAPGWEPLPVQ 6218

Query: 178  YIVWLAKQDRSAA------------LAGWMDYLRGVSEPLMVAYEATAG--QSKPGKTEL 223
            Y  +   Q  S              L  W   L G+ E L +  +      QS  G +  
Sbjct: 6219 YADYALWQRESLGDESDPESLVARQLGYWQQALGGLPEVLELPADRPRPPVQSLRGASAR 6278

Query: 224  LLPAADTAR-LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVE 282
                A T R L   A     TL   V  A  V+L RL+ + DV  GT V+GR +Q   ++
Sbjct: 6279 FTIDAQTHRGLLTIARETNSTLFMVVHAALVVLLERLSSQTDVAIGTPVAGRGEQ--ELD 6336

Query: 283  TMVGLFINAVPVVHYVSGTEA---VVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRG 336
             +VG+F+N + +   V   +    ++AQ       + +  DV +  L E+    R     
Sbjct: 6337 RLVGMFVNTLVLRASVRPDDTFADLLAQVRATDLNAFSHSDVPFERLVEVLDVPRSTAHQ 6396

Query: 337  PLFDSLFVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVS---HLRXXXXXXXX 393
            PLF     F+N   ++++R        +F  +E+ +L   PL V      L         
Sbjct: 6397 PLFQVALSFDN---NESVR-------MEFPGLEISALDA-PLEVAKFDLQLSVGERYVDG 6445

Query: 394  XXXXXXXPYLPAAEI---------GERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLL 444
                    +  + +I          +R   +L  +    D    D++I  AAE  A  + 
Sbjct: 6446 AAAGIAATFNYSTDIFDEQTVLSFADRFGRILHAVSADRDVVLGDIEILDAAEKAA--IA 6503

Query: 445  AARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGP 504
              R   + +        R               G   TY EL   + +LA  L + GVGP
Sbjct: 6504 PVRGPQSIEPRTLPELLRSGVEISPESVAVSYEGREATYRELDELSNQLARVLIDRGVGP 6563

Query: 505  ETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQ 564
            E+ VAL + RS  S             YLPVD  LP  R+  ++  +   L +T A +  
Sbjct: 6564 ESYVALAITRSVESILGIWSIAKAGGAYLPVDPKLPFERIGEMLSDSGAVLGLTVARHHD 6623

Query: 565  LVGTAVPTLALDDPAAVESISRRSAAA-PTVDRRP----EQSAYVIFTSGSTGEPKGVVG 619
             +   VP + LD+ AA E I  RSA A    D R     +  AY+I+TSGSTG+PKGVV 
Sbjct: 6624 DLPGTVPWIVLDETAAAEEIGARSAGAVEDADLRRALTVDHPAYLIYTSGSTGKPKGVVV 6683

Query: 620  TNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAE 679
            T+  + +   +  E                 H  S SFD S   M+         +    
Sbjct: 6684 THRGLANLTREVREHYVVSPDSRFL------HVASPSFDTSVGEMLAAFSAGATLVISPA 6737

Query: 680  EMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRG 739
            ++   D L + I   +++ +  TP+  + +   GL    ++ + +GG+     L    R 
Sbjct: 6738 DVYGGDELADLIRRERVNNVVMTPTALMTVDPDGL--DTVTSVVVGGDTCTPEL--VARW 6793

Query: 740  LSQMAVYNCYGPTEMTVEXXXXXXKDY-RKPTIGTANAGTFGYVFDSALRMVPDGVVGEL 798
                 + N YGPTE TV            + TIG+   G    + DS LR VP+GV GEL
Sbjct: 6794 APGREMRNAYGPTETTVIVTITEPMVAGERVTIGSPLRGVESLILDSRLRPVPEGVPGEL 6853

Query: 799  YLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVK 857
            Y+ G  + RGY  RP +TA RFVA+P   PG RMYRTGD+VR        YVGR+D QVK
Sbjct: 6854 YICGPSVTRGYHNRPSVTAERFVANPFGEPGARMYRTGDVVRWADGHRVEYVGRSDFQVK 6913

Query: 858  IRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDR--TSLVGFVVWQDNMHEDLIKLRAGL 915
            +RG+RVE+GEI+AAL  QP V + AV+V R+     T+LV +V+  D    D   L++ +
Sbjct: 6914 VRGFRVELGEIDAALAAQPNV-EFAVTVGRENPAGLTTLVSYVLPADGATVDPESLKSVV 6972

Query: 916  TERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLC 975
             E LP YMVP+ ++ L  +P+   GKLD     RL E    + +G    + +T  E  + 
Sbjct: 6973 GETLPPYMVPSVVILLDEVPLTGIGKLD---RARLPEPEFVT-AGAEFRAPTTPAEETIA 7028

Query: 976  ELFEEQLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAA 1033
             +F + L      +DD  F  G +S+ A  +V +A +  G R+  R +  A T+  L A 
Sbjct: 7029 GIFADVLGLEQVSVDDRFFDLGGNSLSATRVVSRAGQVFGRRIGVRELFEAPTVSGLAAR 7088

Query: 1034 I---DAAVDSQDAPADADYGAVRPLPMVS---WLYEY--GNYRRFTHTVLLRLPSGIDRS 1085
            I   D  +  +   A  +  A  PL +     W       +   +   + +RL   +D  
Sbjct: 7089 IGTPDENLRPRPVLAPRERSAFVPLSLAQSRMWFINRFDPDSPAYNIPLAVRLTGALDVD 7148

Query: 1086 SIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAV 1145
            +++  +  +LD H++LR+I  ++PEGP  V      + A+ V   +T    SDDEL   +
Sbjct: 7149 ALQSAVFDVLDRHESLRTIYPDSPEGPHQV-----ILPADQVRLDLTPAAVSDDELREQL 7203

Query: 1146 AHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPAN-ILLLTAHHLAVDVVSWHIMLGDLA 1204
                 +VT   D +A         R       P + +L L  HH++ D  S    + D+ 
Sbjct: 7204 ---VEMVTAGFDVTADVPP----IRTRLFEVGPQDYVLALVVHHVSTDGESTAPFVRDVM 7256

Query: 1205 AAWRSLQAGTPPKILP---EFTSYRRWCELMWHRASAPQ--VQDQRDYWAALVREPDPAL 1259
             A+ S  AG  P   P   ++  Y  W   +      P   +  Q  +W   +      L
Sbjct: 7257 VAYASRAAGREPGFAPLPVQYADYAIWQRELLGSEDDPDSLIAAQLAFWKKTLAGVPDLL 7316

Query: 1260 GLRYPDPTRDTWSTLQLTRAAIPVDV-TERVLGAVRRDQGVRELLLAATAMAVASWRRVR 1318
             L    P R    +L+ +R    +D    R L A+ R       +    A AV   R   
Sbjct: 7317 ELPVDRP-RPPVQSLRGSRIDFTIDAEVHRGLAALARRHNASVFMAVHAAFAVLLSRLSG 7375

Query: 1319 AQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAA 1378
             +D + G  +A    GR +  LD    + VG F N   +R+          Q +      
Sbjct: 7376 TEDISVGTPIA----GRGERELD----DVVGMFVNTLALRV----------QVDGQQTFD 7417

Query: 1379 QDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLG-GVADQPW 1437
            + L  +  + LEA  +  + +           LV+ ++P    ++     +G    +   
Sbjct: 7418 EILDRAREADLEAFSHADVPF---------ERLVEVLNPARSMAHHPIFQVGYSFQNTTK 7468

Query: 1438 SLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLT 1497
            + L  P L   P++ E D       +L + +G + EG Q+ G + ++  +F+ + +    
Sbjct: 7469 AELELPDLTVTPLEVEGDTA---QFDLHLILGDSPEGEQMSGVFTFATDLFDAATVKRFA 7525

Query: 1498 GLWQRGIAA 1506
             +++R +AA
Sbjct: 7526 DMFRRVLAA 7534



 Score =  338 bits (866), Expect = 5e-90
 Identities = 397/1463 (27%), Positives = 607/1463 (41%), Gaps = 192/1463 (13%)

Query: 14   LSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDR 73
            LS  Q  ++ +++   D    Y++   V + G +D++ L+ +   +LDRH +LR  + D 
Sbjct: 7113 LSLAQSRMWFINRFDPDS-PAYNIPLAVRLTGALDVDALQSAVFDVLDRHESLRTIYPDS 7171

Query: 74   -DVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRG-PALRVVVLSVPGET 131
             + P  V +      L  +    +  E            FD++   P +R  +  V G  
Sbjct: 7172 PEGPHQVILPADQVRLDLTPAAVSDDELREQLVEMVTAGFDVTADVPPIRTRLFEV-GPQ 7230

Query: 132  KRRMIFTAHHILVDGWSLAVFFTELL---AVXXXXXXXXXXXXXXXXXXYIVW----LAK 184
               +    HH+  DG S A F  +++   A                   Y +W    L  
Sbjct: 7231 DYVLALVVHHVSTDGESTAPFVRDVMVAYASRAAGREPGFAPLPVQYADYAIWQRELLGS 7290

Query: 185  QDR-----SAALAGWMDYLRGVSEPLMVAYEATAG--QSKPG-KTELLLPAADTARLRQW 236
            +D      +A LA W   L GV + L +  +      QS  G + +  + A     L   
Sbjct: 7291 EDDPDSLIAAQLAFWKKTLAGVPDLLELPVDRPRPPVQSLRGSRIDFTIDAEVHRGLAAL 7350

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A RH  ++  AV  A+AV+LSRL+   D+  GT ++GR ++   ++ +VG+F+N + +  
Sbjct: 7351 ARRHNASVFMAVHAAFAVLLSRLSGTEDISVGTPIAGRGER--ELDDVVGMFVNTLALRV 7408

Query: 297  YVSGTEA---VVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSLFVFENAPI 350
             V G +    ++ +  +   ++ +  DV +  L E+    R     P+F   + F+N   
Sbjct: 7409 QVDGQQTFDEILDRAREADLEAFSHADVPFERLVEVLNPARSMAHHPIFQVGYSFQNTTK 7468

Query: 351  DDAIRPATTPDGAQFLPVEMESLT-HYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIG 409
             +   P  T       P+E+E  T  + L ++                     L  +  G
Sbjct: 7469 AELELPDLT-----VTPLEVEGDTAQFDLHLI---------------------LGDSPEG 7502

Query: 410  ERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTF----------------- 452
            E+M  V     D+ D       ++  A++    L AA  +P                   
Sbjct: 7503 EQMSGVFTFATDLFDAAT----VKRFADMFRRVLAAAVDSPRTAVGDLPLAGSDERALVV 7558

Query: 453  -----------DTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHG 501
                       +TT+ +MF                 G   TYA+  AR  RLA  L   G
Sbjct: 7559 SGWNDTERALPETTLADMFA-SAAAENPDVTALVFEGESLTYADFSARVNRLARHLVGRG 7617

Query: 502  VGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAI-TEA 560
            VGPETVV L +PRS                YLP+D   P+ R   ++  A P   + T A
Sbjct: 7618 VGPETVVGLAIPRSVELLVGMYAIAAAGGAYLPIDPDHPAERTAYVLESAQPVCVLATRA 7677

Query: 561  DYSQLVGTAVPTLALD-------DPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGE 613
                L G  V  L LD       DP+ +    R +        RPE +AYVI+TSGSTG 
Sbjct: 7678 VVGGLPGE-VDYLLLDELDLGGIDPSPLTDAERITPL------RPENAAYVIYTSGSTGR 7730

Query: 614  PKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHE 672
            PKGV   + A+ +         +                 + +FD S W+    L  G  
Sbjct: 7731 PKGVAIAHRAIANQLR------WKQSEYPLTAEDSVLLKTAATFDLSVWEFWWALTAGAR 7784

Query: 673  IHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSM---FVQLSAAGLLDHNLSVLALGGEAI 729
            + +   +  RD   L   +A  Q+  +   PS+   FV ++    L     VL +G EA+
Sbjct: 7785 LVVATPDGHRDPSYLAALVAEQQVSTVHFVPSLLSAFVAVAEPAQLVSLTRVLCIG-EAL 7843

Query: 730  NTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPT--IGTANAGTFGYVFDSAL 787
                  + R +S   ++N YGPTE  V        D R  +  IG     T  YV D+ L
Sbjct: 7844 PADTMLRFRDVSDAEIFNLYGPTEAAVSVTHYRCGDERDGSVPIGRPEWNTQTYVLDARL 7903

Query: 788  RMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRP-GQRMYRTGDLVRRLSHGGY 846
              VP GV GELYL+G QLARGY GR  +TA RFVA+P    G RMYRTGDLVR    G  
Sbjct: 7904 HPVPAGVTGELYLAGEQLARGYFGRHDLTAERFVANPFGDAGHRMYRTGDLVRWNRDGNL 7963

Query: 847  AYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTS---LVGFVVWQDN 903
             YVGR+D QVK+RG+R+E+GEIE AL   P V  A V V    DR +   LVG+VV +  
Sbjct: 7964 DYVGRSDFQVKVRGFRIELGEIERALVAHPSVAQAVVVV--HHDRHTGDRLVGYVVPEQG 8021

Query: 904  MHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTA 963
            +  D   +       +P YMVP+ ++ L  LP+N NGKLD          AL     G A
Sbjct: 8022 VSVDDADVLTFAGRSVPGYMVPSALIALDVLPLNINGKLD--------RKALPEPEFGGA 8073

Query: 964  V----SASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVHKARRQ-GLRVD 1017
            V    +  T  E ++  +F + L +    +D   F  G +S+VA  +V +        + 
Sbjct: 8074 VDHYKAPRTPVEEIVAGVFADVLGHERVSVDTSFFDLGGNSLVATRVVARVNAALDTSIG 8133

Query: 1018 PRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPL-----PMVSWLYEYGNY----R 1068
             R +  A T+  L A  + + DS  A   A     RP      P  S ++    +     
Sbjct: 8134 VRELFEAPTVIALSARAEQS-DSAGANRPALVPQPRPARIPLSPAQSRMWFINQFDTASA 8192

Query: 1069 RFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLV----TREPAAVRA 1124
             +   + +RL   +D S++E  L  +++ H+TLR+   +T +GP  V    TR   ++  
Sbjct: 8193 AYNIPLAIRLTGHLDVSALEQALGDVVERHETLRTTYPDTGDGPGQVVLSRTRSFTSLDV 8252

Query: 1125 EDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLL 1184
            E+V     L E               +VT   D +    VRA   R    +    ++L++
Sbjct: 8253 ENVADENALRE-----------RVISLVTAGFDVAKTVPVRARLLRIDAEQ----HVLVI 8297

Query: 1185 TAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILP---EFTSYRRW-CELMW-HRASAP 1239
              HH++ D  S   +  D+  A+ +  AG+ P   P   ++  +  W  EL+    AS  
Sbjct: 8298 VVHHISSDGASTAPLARDVVIAYSARAAGSEPAWAPLDVQYADFSLWQHELLGDENASDS 8357

Query: 1240 QVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAA-----IPVDVTERVLGAVR 1294
                Q DYW   +      L    P PT       Q  R A     I  ++ +R LGA+ 
Sbjct: 8358 LATKQIDYWRTTLSGLPDVL----PLPTDRPRPPAQSMRGANFDFEIDAELRDR-LGALA 8412

Query: 1295 RDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNA 1354
            R+      ++A  A++V   R     D A G  +     GR +A LD    + VG F N 
Sbjct: 8413 REHNASLFMVAHAALSVLLARLSATDDIAVGTAI----EGRGEAALD----DLVGMFVNT 8464

Query: 1355 FPVRLGAGAAAVDIEQAERDPVA 1377
              +R     A VD+++   D +A
Sbjct: 8465 LVLR-----AQVDVDKTFADLLA 8482



 Score =  291 bits (746), Expect = 4e-76
 Identities = 379/1427 (26%), Positives = 579/1427 (40%), Gaps = 147/1427 (10%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            L LS  Q+ ++ L++  +     Y++   V + G +D+  L  +   ++ RH  LR  F 
Sbjct: 3802 LPLSLAQQRMWFLNRF-DPSSPAYNVPLTVRLRGELDVAALAAALSDVVARHEVLRTVFP 3860

Query: 72   DRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERR-----RPFDLSRGPALRVVVLS 126
            D D      I+P        +    P +    A  +R        FD++    +R  +  
Sbjct: 3861 DSDSGAHQVILPPADI----DLALEPVDVREEALRDRMFEFGSTGFDVTDTIPVRARLFR 3916

Query: 127  VPGETKRRMIFTAHHILVDGWSLAVFFTELL---AVXXXXXXXXXXXXXXXXXXYIVW-- 181
            + G     ++   HHI  DG S      +++   A                   Y +W  
Sbjct: 3917 L-GAADHVLVLVMHHIASDGASTLPLARDVMTAYAANLDGTQPAWPVLPVQYGDYALWQR 3975

Query: 182  --LAKQDRSAALAG-----WMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTA--- 231
              L  +D   +LA      W   L GV + L +  +      +P  T   +  A      
Sbjct: 3976 DVLGSEDDPDSLAAAQIDFWSKTLAGVPDVLALPID------RPRPTVRSMAGASVGFSV 4029

Query: 232  ------RLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMV 285
                  RL + A  H ++L   +  + +V+L+RL+   D+  GT V+GR D+   +E +V
Sbjct: 4030 DEDIHRRLGEVARAHNVSLFMVLHASLSVLLARLSASTDIAIGTAVAGRGDE--ALENLV 4087

Query: 286  GLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAM---RDVSYLSLSEI---QREHGRGPLF 339
            G+F+N + +   V    +      QV+ Q  A    +DV +  L ++    R     PLF
Sbjct: 4088 GMFVNTLVLRTEVEPGTSFAELLEQVRTQDLAAFSNQDVPFEQLVDVLKPTRSTAYSPLF 4147

Query: 340  DSLFVFENAPIDDAIRPATTPDGAQFLPVEME-SLTHYPLTVVSHLRXXXXXXXXXXXXX 398
              +   +   I     P+    G +  P  ++   + + LTV   LR             
Sbjct: 4148 QVVLTHQVNGI-----PSLEFAGLEATPGAVDVEFSKFDLTV--DLRELWSDEGAPTGIT 4200

Query: 399  XXPYLPAAEI---------GERMLTVLRQLP----DIGDGTPDDLDIRTAAELKAHGLLA 445
                  A EI          +R + +L  +     DI  G    LD    AEL    +  
Sbjct: 4201 GVLGF-ATEIFDAETVQGFADRFVRILAAVAGGGTDIAVGDIPILDAEETAELTP--VRG 4257

Query: 446  ARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPE 505
                P   TT+ E+    V             G   TY EL   + R+A  L E GVG E
Sbjct: 4258 IEGTPP--TTLVELLSAAVAANPDGVAIVSG-GDSITYRELDELSNRVARILIERGVGAE 4314

Query: 506  TVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQL 565
            T V L + RS  S             Y+P+D   P  R+  +V  +  +L ++ +     
Sbjct: 4315 TFVGLGITRSIVSIAGIWAVAKSGGAYVPIDPGYPDERIAHMVTDSGVSLGLSVSSEVGR 4374

Query: 566  VGTAVPTLALDDPAAVESISRRSAA-APTVDRR----PEQSAYVIFTSGSTGEPKGVVGT 620
            +   V  L LD      + ++ S A    V+RR    P  SAYVI+TSG+TG+PKGVV T
Sbjct: 4375 LPADVDWLVLDSEDFENAAAQYSTAPVAEVERRTAVTPANSAYVIYTSGTTGQPKGVVVT 4434

Query: 621  NAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEE 680
            +  + ++ A+  ER                H  S SFDAS   ++  +      +    +
Sbjct: 4435 HRGLANFAAEQRERY------RVTTDSRTLHFASPSFDASVLELLLAVGAGATMVIAPTD 4488

Query: 681  MRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGL 740
            +       + +   ++     TPS    +  +GL D    V   GGEA+   L    R  
Sbjct: 4489 VYGGPEFAKFLREHRVTHGFVTPSALASVDPSGLDDFQFVVA--GGEAVPAEL--AARWA 4544

Query: 741  SQMAVYNCYGPTEMTVEXXXXXXKDYRKP-TIGTANAGTFGYVFDSALRMVPDGVVGELY 799
               +++N YGPTE T+            P TIG    GT   V D  LR VP G+ G+LY
Sbjct: 4545 PGRSLFNGYGPTETTIMTNISDPMAADGPVTIGGPIRGTSALVLDDRLRPVPVGIAGDLY 4604

Query: 800  LSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYA----YVGRADT 854
            LSG  LARGY  R  +TA RFVA+P   PG RMYRTGD+VR       A    YVGR+D 
Sbjct: 4605 LSGLGLARGYHRRTPLTAGRFVANPYGEPGDRMYRTGDVVRWTKDADGALTVDYVGRSDQ 4664

Query: 855  QVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTS-LVGFVVWQDNMHEDLIKLRA 913
            QVK+RG+R+E+GEI+A L   P V  A  SVL      S LV +V+    +  D+ ++  
Sbjct: 4665 QVKVRGFRIELGEIDAVLAKHPAVDFATTSVLPGPSGDSVLVSYVLPVPGVEVDVPRMLD 4724

Query: 914  GLTERLPSYMVPARIVTLPRLPVNANGKLDGHAL---DRLAEDALTSVSGGTAVSASTDT 970
             + E +P+YMVP+ IVTL  +P+   GKLD  AL   + LAED     +G       T  
Sbjct: 4725 FVGEFVPTYMVPSTIVTLDAIPLTPVGKLDRRALPEPEFLAEDREFRAAG-------TAL 4777

Query: 971  ERVLCELFEEQLNA-VPHIDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIR 1028
            E+ +  +F E L   V   DD  F  G +S+ A  ++ +     G+    R +  A T+ 
Sbjct: 4778 EQRVAAVFAEVLGVDVVGADDSFFTLGGNSLAATRVMARINEAVGIDAPVREIFEAPTVA 4837

Query: 1029 QLGAAI-DAAVD-SQDAPADADYGAVR-PLPMVSWLYEYGN-----YRRFTHTVLLRLPS 1080
            QL   + +  VD     P  A     R PL +      Y N        +   + LRL  
Sbjct: 4838 QLARRLEELGVDGGARPPVTAGPRPDRLPLSLAQQRMWYANRFDPESAEYNIPLALRLTG 4897

Query: 1081 GIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDE 1140
             +D  ++   +  ++  H++LR++  ++ +GP  V    +  ++   + R+      + E
Sbjct: 4898 ALDVDALRSAIADVVARHESLRTVYPDSVDGPYQVVLPASDTKSGLDVVRV----ADEQE 4953

Query: 1141 LASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIML 1200
            L   V   A   +   D +A   VRA  F   E      ++L++  HH++ D  S   + 
Sbjct: 4954 LRERVVALA---SAGFDVTADVPVRAALFELGER----DHVLVVVVHHISADGSSMAPLA 5006

Query: 1201 GDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQD-------QRDYWAALVR 1253
             DL  A+ +   G  P   P    Y  +   +W R       D       Q  YW   + 
Sbjct: 5007 RDLFGAYGARVQGEEPGFSPLPVQYPDFA--LWQRNLLGSEDDPDSLAGKQIAYWTHALG 5064

Query: 1254 EPDPALGLRYPDPTRDTWSTLQ--LTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAV 1311
            +    L L   D  R      Q  L    I  DV  R L  + +       ++  TA+AV
Sbjct: 5065 DAPEVLDLP-ADRPRPAVRNPQGGLIEFEIGQDV-HRSLNDLAQTHQASLFMVVHTALAV 5122

Query: 1312 ASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
               R     D +    VA    GR D  LD    + VG F N   +R
Sbjct: 5123 LLGRLSNTSDISVSTPVA----GRGDRALD----DLVGMFVNTLVLR 5161



 Score =  286 bits (731), Expect = 2e-74
 Identities = 266/917 (29%), Positives = 405/917 (44%), Gaps = 72/917 (7%)

Query: 482  TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPS 541
            TY+EL  RA +LA  L   GVGP+++VA+ L RS                YLP DVT P+
Sbjct: 5465 TYSELDVRANKLARLLISRGVGPDSLVAVALDRSADLVVSLLAVVKAGGGYLPTDVTYPA 5524

Query: 542  ARVESIVRQASPALAITE-ADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDR---- 596
             R+E ++  A P + +T  A  + L  T +PT+ LD    +  ++   A  P  +R    
Sbjct: 5525 DRLEFMLTDARPVVILTSIAHAAGLPDTGIPTVLLDADETLIDLADLDAG-PVEERERHA 5583

Query: 597  --RPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWS 654
              R    AYVI+TSGSTG PKGV+ T++AV+  F    +R +              H+++
Sbjct: 5584 ALRANNLAYVIYTSGSTGRPKGVMVTHSAVVQLF----DRTFGEFGFDDSDVWTLFHSYA 5639

Query: 655  LSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGL 714
              F   W+    LL G  + + D    R  D     ++  ++ ++  TPS F QLSAA  
Sbjct: 5640 FDFSV-WELWGALLYGGRLVVVDYLTSRSPDEFRALLSRERVTVLSQTPSAFYQLSAADR 5698

Query: 715  L-----DHNLSVLALGGEAINTGL---WDQLRGLSQMAVYNCYGPTEMTVEXXXXXX--- 763
                  D  L  +  GGEA++ G    W      +   + N YG TE TV          
Sbjct: 5699 ALETPDDLALRYVIFGGEALDLGQLSKWYDRHPETAPRLVNMYGITETTVHVTHLALDRK 5758

Query: 764  --KDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFV 821
              +      +G    G   +V DS LR VP GV GE+Y+SG QL RGY+ RP +T+ RFV
Sbjct: 5759 FAESASASVVGEPIDGLRVHVLDSRLRPVPTGVSGEMYISGGQLTRGYLQRPDLTSTRFV 5818

Query: 822  ADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHD 880
            A+P    G R+YR+GD+ R  S G   Y+GR+D+Q+++RG+R+E+GEIE+AL   PGV  
Sbjct: 5819 ANPFGATGGRLYRSGDVARWNSAGLLEYLGRSDSQIQLRGFRIELGEIESALLRAPGVAA 5878

Query: 881  AAVSVLRQQD-RTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNAN 939
            +   VLR  +    LVG+VV +        +++   +  L SYMVP  ++ L  +P+  N
Sbjct: 5879 SVAVVLRDAEVGDRLVGYVVPESGAILVPTEIKDFASGFLTSYMVPDVVMVLGAMPITVN 5938

Query: 940  GKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPHID--DDLFLFGM 997
            GKLD  AL       L S      V+ ST  E ++  +F E L  V  +   D  F  G 
Sbjct: 5939 GKLDRKALPAPEITVLQS----EFVAPSTPVEEIVAGVFAEVL-GVERVGTADSFFDLGG 5993

Query: 998  DSIVAISLVHK-ARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQD------APADADYG 1050
            +SI A  L  +     G ++  R      T+ +L A ++A   + +      A A  D  
Sbjct: 5994 NSISATRLTARLTAALGAQLSVRECFEHPTVAELAALLEATAGTAEHRPTLVARARPDRI 6053

Query: 1051 AVRPLPMVSWLYEY--GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTET 1108
             +       W       +   +   + +RL   ID +++      +++ H++LR++    
Sbjct: 6054 PLSLAQQRMWFINQFDPSSPAYNLPLAVRLTGSIDTAALNAAWADVVERHESLRTVFPVG 6113

Query: 1109 PEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIW 1168
             E    +      + A DV++ +T    +D++   A           +  +    V    
Sbjct: 6114 DEDAHQI-----VLPAADVVSDLTPTPVADEQDLYARMRELGATGFDVTETVPVRVACFE 6168

Query: 1169 FRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRW 1228
               T+H      IL++  HH++ D  S   +  D+  A+ +  AGT P   P    Y  +
Sbjct: 6169 VNPTDH------ILMMVVHHISADGASLAPLFTDIMTAYAARAAGTAPGWEPLPVQYADY 6222

Query: 1229 CELMWHRASAPQVQDQRDYWAALVREPDPALG-----LRYP-DPTRDTWSTLQLTRAAIP 1282
               +W R S     D     A  +     ALG     L  P D  R    +L+   A   
Sbjct: 6223 A--LWQRESLGDESDPESLVARQLGYWQQALGGLPEVLELPADRPRPPVQSLRGASARFT 6280

Query: 1283 VDV-TERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD 1341
            +D  T R L  + R+      ++   A+ V   R     D A G  VA    GR +  LD
Sbjct: 6281 IDAQTHRGLLTIARETNSTLFMVVHAALVVLLERLSSQTDVAIGTPVA----GRGEQELD 6336

Query: 1342 TDTTNTVGWFTNAFPVR 1358
                  VG F N   +R
Sbjct: 6337 ----RLVGMFVNTLVLR 6349



 Score =  256 bits (654), Expect = 2e-65
 Identities = 273/949 (28%), Positives = 410/949 (43%), Gaps = 89/949 (9%)

Query: 478  GVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDV 537
            GV  T  EL+ RA +LA EL   GVGP+ VVAL++PRS                Y P D 
Sbjct: 3214 GVTTTRGELNRRANQLARELRAQGVGPDDVVALIVPRSLEWVIGMIAAWKLGAAYSPFDQ 3273

Query: 538  TLPSARVESIVRQASPALAITEADYSQL----VGTAV--PTLALDDPAAVESISRRSAAA 591
                 R+  ++  +     +    +S L    +G AV    + +DD   +E ++    + 
Sbjct: 3274 DWGLDRIVGLIEDSGTRAVVVTNSWSGLTEAPLGNAVLDAAIVVDDADTIERLAAHDVSD 3333

Query: 592  PTVD-----RRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXX 646
               D         + AYVI TSGSTG PK  +     V + +  +   +           
Sbjct: 3334 FAHDPWSDAEASSRLAYVISTSGSTGRPKPTMVPMIGVSNTYQWYRHALDFTEGTGVLV- 3392

Query: 647  XXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSM 705
                 A S  FD + + + V +  G  +HL  A+   D   ++  I  G + + +  PS 
Sbjct: 3393 -----ANSPLFDQTQKNIWVSVAYGGVMHL--AQPGFDPLPILRQIGTGDVQIANMAPSA 3445

Query: 706  FVQLS---AAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMT------- 755
            F  LS     G+L   L ++ +GGE +       L G +Q  + N YGPTE +       
Sbjct: 3446 FEVLSDLDTEGVLG-KLDIVVVGGEQLRPAACSALIG-TQTRLINTYGPTEASATDSSYE 3503

Query: 756  VEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGM 815
            V+      + +  P  G A  G   +V D  +R VP GV GELY+ G  LARGY G  G+
Sbjct: 3504 VDLSSADAEQWPVP-FGAAFEGVEYHVLDGRMRPVPPGVTGELYIGGIVLARGYGGMTGI 3562

Query: 816  TAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRG 874
            TA+RFVA+P    G R+YRTGDLVR   HG   +VGR+D QVKIRG R+E+GEIE+AL  
Sbjct: 3563 TASRFVANPFGNAGTRLYRTGDLVRERDHGQLVFVGRSDFQVKIRGLRIELGEIESALTA 3622

Query: 875  QPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRL 934
               V  + V V   +    LV +V     +  D+  +   L   LPS+M+P  ++ L  +
Sbjct: 3623 NSDVLQSVVVVHESEQGPRLVSYVTAAAGVELDIDAILDDLHRALPSHMIPDTVMVLDEM 3682

Query: 935  PVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV-PHIDDDLF 993
            P+NAN K+D  AL     + + + S    V+  T  E V+  +F + ++A    +D+  F
Sbjct: 3683 PLNANLKVDRKAL----PEPVFATSTVEFVAPRTPLEEVVAGIFGDVVSATRVSVDESFF 3738

Query: 994  LFGMDSIVAISLVHK-ARRQGLRVDPRMVLTATTIRQLGAAI-DAAVDSQDAPADADYGA 1051
              G +S+ A  +  +     G  V  R +  A T+  L   + D A      PA      
Sbjct: 3739 DLGGNSLSATRVAARVTSATGTEVGIRDLFEAPTVATLAKLVEDRAHHGSTRPALVAGER 3798

Query: 1052 VRPLPMVSWLYEYGNYRRFTHT-------VLLRLPSGIDRSSIELMLQLLLDGHDTLRSI 1104
             R LP+           RF  +       + +RL   +D +++   L  ++  H+ LR++
Sbjct: 3799 PRELPLSLAQQRMWFLNRFDPSSPAYNVPLTVRLRGELDVAALAAALSDVVARHEVLRTV 3858

Query: 1105 LTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMV 1164
              ++  G   V   PA +  +  L  + + E +  +           VTD I       V
Sbjct: 3859 FPDSDSGAHQVILPPADI--DLALEPVDVREEALRDRMFEFGSTGFDVTDTIP------V 3910

Query: 1165 RAIWFR--GTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPP--KILP 1220
            RA  FR    +H      +L+L  HH+A D  S   +  D+  A+ +   GT P   +LP
Sbjct: 3911 RARLFRLGAADH------VLVLVMHHIASDGASTLPLARDVMTAYAANLDGTQPAWPVLP 3964

Query: 1221 -EFTSYRRWCELMWHRASAPQ--VQDQRDYWA-ALVREPDP-ALGLRYPDPTRDTWSTLQ 1275
             ++  Y  W   +      P      Q D+W+  L   PD  AL +  P PT        
Sbjct: 3965 VQYGDYALWQRDVLGSEDDPDSLAAAQIDFWSKTLAGVPDVLALPIDRPRPT-----VRS 4019

Query: 1276 LTRAAIPVDVTE---RVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEG 1332
            +  A++   V E   R LG V R   V   ++   +++V   R   + D A G  VA   
Sbjct: 4020 MAGASVGFSVDEDIHRRLGEVARAHNVSLFMVLHASLSVLLARLSASTDIAIGTAVA--- 4076

Query: 1333 HGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDL 1381
             GR D  L+    N VG F N   +R          E  E+  V  QDL
Sbjct: 4077 -GRGDEALE----NLVGMFVNTLVLRTEVEPGTSFAELLEQ--VRTQDL 4118



 Score = 84.7 bits (208), Expect = 9e-14
 Identities = 120/540 (22%), Positives = 206/540 (38%), Gaps = 39/540 (7%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            V  A P+ E V  LS  Q+ ++ +++  +     Y++   V + G +D++ +  +   +L
Sbjct: 2597 VLVARPRPERV-PLSMAQQSMWLMNRF-DTASSAYNIPLAVRLSGSLDIDAMSSAVSDVL 2654

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAA-LPWSERVATPAEFDSIARSERRRPFDLSRGPA 119
             RH +LR  F D       QIV         +    T AE  +         FD++  P 
Sbjct: 2655 ARHESLRTVFPDAGDGPYQQIVDTEQVPFDLTPVPVTEAELHTALTEFATEGFDVTVAPP 2714

Query: 120  LRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY- 178
            LR+ + +   E++  ++   HHI  DG S++    +++                    Y 
Sbjct: 2715 LRIRLFAT-SESEFLLVLVVHHICADGASMSPLARDVMVAYSARTAGAAPLWQPLPVQYP 2773

Query: 179  --IVW----LAKQDRSAALAG-----WMDYLRGVSE--PLMVAYEATAGQSKPGKTELLL 225
               +W    L     + +LAG     W D L G  E   L + +   A QS  G +    
Sbjct: 2774 DFALWQREVLGDPADTQSLAGKQIAHWADTLAGAPELIDLPLDHARPARQSMRGDSIDFA 2833

Query: 226  PAADTARLRQWAGRH-GLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETM 284
               +  R  +  G+  G +L      A   +LSRL++  D+  GT ++ R DQ   ++ +
Sbjct: 2834 ITPELRRGLEAVGKERGASLFMVTHAALTTLLSRLSNSDDITVGTPLAARSDQ--ALDDL 2891

Query: 285  VGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAM---RDVSYLSLSE---IQREHGRGPL 338
            VG+F+N + +  +V   ++      +V+    A     DV +  + E   I+R     PL
Sbjct: 2892 VGMFVNTLVLRTHVRPGDSFAELVERVREGDLAAFGNSDVPFEKIVEALRIRRSAAYSPL 2951

Query: 339  FDSLFVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVV------SHLRXXXXXXX 392
            F  +  F+N  +D    P  T    +    +M     Y LT+                  
Sbjct: 2952 FQVMLSFQNNRMDALELPGLTVHVIE----DMAQGAKYDLTLTITEKADESGEPAGLGGR 3007

Query: 393  XXXXXXXXPYLPAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTF 452
                        A  I ER + +L  +         D+DI T  E +   L  AR A T 
Sbjct: 3008 FTFATDLFERSTAERISERFVRILEAVVTDPGVAVGDIDILT--EHERAKLSQARPARTM 3065

Query: 453  DTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVL 512
                                     G++ TY E   R   ++  L+E G+GP+ +V++VL
Sbjct: 3066 TVRELPQLLAAAVEVAPDAVAVAHDGMQVTYREFDERLRLMSAPLSERGMGPDAIVSVVL 3125



 Score = 69.3 bits (168), Expect = 4e-09
 Identities = 125/560 (22%), Positives = 202/560 (36%), Gaps = 84/560 (15%)

Query: 10   DVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAA 69
            D L LS  Q+ ++  ++   +  + Y++   + + G +D++ LR +   ++ RH +LR  
Sbjct: 4863 DRLPLSLAQQRMWYANRFDPESAE-YNIPLALRLTGALDVDALRSAIADVVARHESLRTV 4921

Query: 70   FWDRDVPKPVQIVPVHAALPWSE--------RVATPAEFDSIARSERRRPFDLSRGPALR 121
            + D  V  P Q+V     LP S+        RVA   E      +     FD++    +R
Sbjct: 4922 YPD-SVDGPYQVV-----LPASDTKSGLDVVRVADEQELRERVVALASAGFDVTADVPVR 4975

Query: 122  VVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY--- 178
              +  + GE    ++   HHI  DG S+A    +L                     Y   
Sbjct: 4976 AALFEL-GERDHVLVVVVHHISADGSSMAPLARDLFGAYGARVQGEEPGFSPLPVQYPDF 5034

Query: 179  IVW----LAKQDRSAALAG-----WMDYLRGVSEPLMVAYEATAGQSKP-------GKTE 222
             +W    L  +D   +LAG     W   L    E L    +  A + +P       G  E
Sbjct: 5035 ALWQRNLLGSEDDPDSLAGKQIAYWTHALGDAPEVL----DLPADRPRPAVRNPQGGLIE 5090

Query: 223  LLLPAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVE 282
              +       L   A  H  +L   V  A AV+L RL++  D+   T V+GR D+   ++
Sbjct: 5091 FEIGQDVHRSLNDLAQTHQASLFMVVHTALAVLLGRLSNTSDISVSTPVAGRGDR--ALD 5148

Query: 283  TMVGLFINAVPV---VHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRG 336
             +VG+F+N + +   V   +    ++ Q  +V   +    DV +  + E+    R     
Sbjct: 5149 DLVGMFVNTLVLRTDVDQNARFSTLLTQAREVDLNAFGNADVPFEQIVEVLRPSRTAAYA 5208

Query: 337  PLFDSLFVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXX 396
            PL   +  F+N       RP    DG     +E    T      V+              
Sbjct: 5209 PLAQVMLSFQNLE-----RPKLELDGLTVEVLESGLTTSKTDLGVAVEERFDEGSVANGM 5263

Query: 397  XXXXPYL-------PAAEIGERMLTVLRQLPDIGDGTPDDLDIRT-------------AA 436
                 Y              +R + VL  +    D    D+DI T             A 
Sbjct: 5264 RGWFSYATDLFDESTVRGFADRFVRVLEAVTVDADAVVGDIDILTEDEKAGLAVPEEGAQ 5323

Query: 437  ELKAHG----LLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACR 492
             L +H     L A +S P       E+ +                G   TYA+L  ++  
Sbjct: 5324 SLMSHSISEELTATKSLP-------ELLDGAAS-INPDGIALSHNGTDVTYAQLRDKSAE 5375

Query: 493  LAGELAEHGVGPETVVALVL 512
            LA  LA  G+GPE  V + L
Sbjct: 5376 LARTLAGVGIGPEAAVTVAL 5395



 Score = 62.0 bits (149), Expect = 6e-07
 Identities = 85/375 (22%), Positives = 151/375 (40%), Gaps = 29/375 (7%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            + LSP Q  ++ ++Q  +     Y++   + + G +D+  L ++   +++RH  LR  + 
Sbjct: 8172 IPLSPAQSRMWFINQF-DTASAAYNIPLAIRLTGHLDVSALEQALGDVVERHETLRTTYP 8230

Query: 72   DRDVPKPVQIVPVHAALPWSERVATPAEFDSIAR---SERRRPFDLSRGPALRVVVLSVP 128
            D     P Q+V        S  V   A+ +++     S     FD+++   +R  +L + 
Sbjct: 8231 DTG-DGPGQVVLSRTRSFTSLDVENVADENALRERVISLVTAGFDVAKTVPVRARLLRID 8289

Query: 129  GETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYI---VW---- 181
             E +  ++   HHI  DG S A    +++                    Y    +W    
Sbjct: 8290 AE-QHVLVIVVHHISSDGASTAPLARDVVIAYSARAAGSEPAWAPLDVQYADFSLWQHEL 8348

Query: 182  LAKQDRSAALAG-----WMDYLRGVSE--PLMVAYEATAGQSKPGKT-ELLLPAADTARL 233
            L  ++ S +LA      W   L G+ +  PL         QS  G   +  + A    RL
Sbjct: 8349 LGDENASDSLATKQIDYWRTTLSGLPDVLPLPTDRPRPPAQSMRGANFDFEIDAELRDRL 8408

Query: 234  RQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVP 293
               A  H  +L      A +V+L+RL+   D+  GT + GR +    ++ +VG+F+N + 
Sbjct: 8409 GALAREHNASLFMVAHAALSVLLARLSATDDIAVGTAIEGRGE--AALDDLVGMFVNTLV 8466

Query: 294  VVHYVSGTEA---VVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSLFVFEN 347
            +   V   +    ++AQ  Q    +    DV +  L EI   +R     PLF     F+N
Sbjct: 8467 LRAQVDVDKTFADLLAQVRQHDLGAFTHTDVPFERLVEILQPERSTAFSPLFQVALAFQN 8526

Query: 348  APIDDAIRPATTPDG 362
                    P  T +G
Sbjct: 8527 IEQAHLELPGLTVEG 8541


>tr|B1VL66|B1VL66_STRGG Tax_Id=455632 SubName: Full=Putative
            NRPS;[Streptomyces griseus subsp. griseus]
          Length = 5169

 Score =  718 bits (1854), Expect = 0.0
 Identities = 536/1531 (35%), Positives = 731/1531 (47%), Gaps = 77/1531 (5%)

Query: 9    EDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRA 68
            ED+L LSPLQEGL       E G D+Y++Q V+D+ G +D  +LR +A+A+LDRH NLRA
Sbjct: 7    EDILPLSPLQEGLLFHALYDESGDDVYTVQVVLDLGGGLDAAVLRATARALLDRHANLRA 66

Query: 69   AFWDRDVPKPVQIVPVHAALPWSERVATP-------AEFDSIARSERRRPFDLSRGPALR 121
             F      +PVQ++     +PW E    P       AE + I   E+   FDL+R P +R
Sbjct: 67   GFLHPKQSRPVQVISRAVDVPWREDDLRPLGEDVRAAELERIQAEEKAHAFDLARPPLMR 126

Query: 122  VVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVW 181
              ++ +  +   R++ T HHIL+DGWS +V   ELL V                  ++ +
Sbjct: 127  YRLVRLADDA-HRLLCTFHHILLDGWSTSVLLGELLEVYGNGGDASVLPPVTPFREHLAF 185

Query: 182  LAKQDRSAALAGWMDYLRGVSEPL-MVAYEATAGQSKPGKTELLLPAADTARLRQWAGRH 240
            LA+QDR A+   W   LRG+  P  +V  +       P +  L L AA T  L       
Sbjct: 186  LARQDRRASDEAWRRALRGIDAPTRLVPSDPAREVVHPEQLALELSAAATEALSARLRAA 245

Query: 241  GLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSG 300
            GLT ++AV  +WA++LS LT R+DVVFGTVVSGRP ++PGVE MVG+ IN++PV   ++G
Sbjct: 246  GLTFSSAVHGSWALLLSVLTGRQDVVFGTVVSGRPPEVPGVERMVGMLINSLPVRVRLNG 305

Query: 301  TEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPID----DAIRP 356
             +++      +Q +   M +  Y  + +I R  G   LFD+   FEN P D      +  
Sbjct: 306  GDSLGDVLAGLQGEHLEMMNHQYTGMRDIHRLSGHPELFDTYVAFENFPFDLQDLRDLAG 365

Query: 357  ATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVL 416
                DG   L        HYPL +VSH+                       IG+R++ +L
Sbjct: 366  DLAIDGFDVL-----DANHYPLCLVSHVYEGRLRLLLNYRPDLFRPEQVGVIGDRLVRIL 420

Query: 417  RQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVW-EMFERQVQXXXXXXXXXX 475
              L      T   LD+    E +   +    + P  +   + E+F  Q +          
Sbjct: 421  ETLTQDLTRTVAGLDVLADGERERLVVADGAAGPAVEQAAFPELFAAQAE-RTPDAVAVE 479

Query: 476  XXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPV 535
              G+  TYAEL AR   LA  L   GVGPET+VALVL RS  S             +LPV
Sbjct: 480  SGGLSLTYAELDARTGELAARLTAEGVGPETIVALVLGRSVESVIGSLAVMRAGAAFLPV 539

Query: 536  DVTLPSARVESIVRQASPALAITEADYSQLV----GTAVPTLALDDPAAVESISR-RSAA 590
            D   P+ RV  +   A PA  +T   Y + V    G AV  L   D AA  S  R    +
Sbjct: 540  DPDYPAERVAFMFDDARPAAVLTTEAYEKAVPRSGGAAVLVLDPADGAAARSAPRSEPRS 599

Query: 591  APTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXX 650
            AP         AYVI+TSGSTG PKGVV T+A + ++ A   ER                
Sbjct: 600  APRAPLPVASPAYVIYTSGSTGVPKGVVVTHAGLAAFAATERERFAVTGDSRVLQFS--- 656

Query: 651  HAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQL 709
               S SFDAS  +  + L  G  + + D   +   + L E IA  ++      P+    +
Sbjct: 657  ---SPSFDASVLELCMALTSGAALVVPDPGPLA-GEPLAEVIAGRRVTHALIPPAALASV 712

Query: 710  SAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYR-- 767
             AA L     S L +GG+A +  L    R      + N YGPTE TV        +    
Sbjct: 713  PAADL--PGFSCLIVGGDACSPEL--VARWAPGRRMVNAYGPTESTVAVSMSIPLEASGG 768

Query: 768  KPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-R 826
             P IG     T  YV D +LR  P G  GELY++GA LARGY+ RPG+TA RFVADP   
Sbjct: 769  VPPIGAPVHDTRAYVLDGSLRPAPLGAEGELYVAGAGLARGYLRRPGLTAERFVADPFGA 828

Query: 827  PGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVL 886
            PG+RMYRTGDLVR    G   + GR D QVK+RG+R+E+GE+E+ L     V  AAV   
Sbjct: 829  PGERMYRTGDLVRLREDGQLEFAGRVDDQVKVRGFRIELGEVESVLARHDRVDRAAVVAH 888

Query: 887  -RQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGH 945
                    LV +VV       D   LRA + E LP YM P+ ++ L  LP+  NGKLD  
Sbjct: 889  GTGAGGKQLVAYVVPAGPEPLDAETLRAHVAELLPEYMTPSLVIPLDALPLMINGKLDRK 948

Query: 946  ALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV-PHIDDDLFLFGMDSIVAIS 1004
            A   L    +T   G     A    E +LC L+ E L      ++   F  G DSI +I 
Sbjct: 949  A---LPAPEITVTEGRAPADA---REELLCTLYAEVLGVERVGVEQSFFELGGDSIGSIQ 1002

Query: 1005 LVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADAD-YGAVRPLPMVSWLYE 1063
            L+ +AR+ GLR  PR V T  T+  L A           PA  D  G V   P++ W  E
Sbjct: 1003 LISRARKAGLRFTPRDVFTHKTVEALAAVATEVAAPTRRPAVPDGVGGVPLTPIIHWFSE 1062

Query: 1064 Y-GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPE-GPRLVTREP-A 1120
            + G    F   + L +P+G+D + I  +LQ  LD HD LR  LT   + G   +   P  
Sbjct: 1063 HSGPVAPFNQAMALPVPAGLDSARIAGVLQTFLDHHDALRLRLTRIEDIGEWTLEITPTG 1122

Query: 1121 AVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPAN 1180
             V A + L R+       D L +          +++ P  G MV A+WF   +   D   
Sbjct: 1123 TVAAAESLYRVDASGLDADALRALTEKEFTAAQNRLAPERGRMVEAVWF---DQGPDLPG 1179

Query: 1181 ILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQ 1240
             LLL  HHL+VD VSW I+L +  AA  +   G      P  TS+R W   +   A  P 
Sbjct: 1180 RLLLVIHHLSVDGVSWRILLPEFTAALEAAARGGSFTPEPVGTSFRSWARQLTAAAGEPD 1239

Query: 1241 VQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRR--DQG 1298
               +   W +++ EPDP L  R PDP  DT +T       +P D+TE +LG V      G
Sbjct: 1240 RIRELPLWRSMLSEPDPLLTDRLPDPETDTLATAGHLTLRLPADLTEPLLGRVPTAFSTG 1299

Query: 1299 VRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
            + E+LL A A+AVA WRR+R +  ++ VLV LEGHGR + V   D + TVGWFT+ +PVR
Sbjct: 1300 INEVLLTALAVAVADWRRLRGRGDSSSVLVGLEGHGREEIVEGADLSRTVGWFTSLYPVR 1359

Query: 1359 LGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVD--GVAELVDAVD 1416
            L  G A  D      D V A   + +V   L AIP++G+ +GLLRY++    A L    +
Sbjct: 1360 LDPGEAGGD------DLVTA---LKAVKEQLRAIPDNGIGFGLLRYLNPRTAAALARFAE 1410

Query: 1417 PQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQ 1476
            PQI F+YLGR+   G  D+      G   D L    +P  PL + L  +       +G +
Sbjct: 1411 PQIGFNYLGRI---GGGDE------GAGADGLGGGADPATPLPYTLTANAVTETHGDGPR 1461

Query: 1477 LIGNWRWSDAVFERSDIDHLTGLWQRGIAAL 1507
            L   W W   +    D+  L   W   + +L
Sbjct: 1462 LAVTWTWPGGLLTEDDVRPLAEAWFAALRSL 1492



 Score =  538 bits (1387), Expect = e-150
 Identities = 463/1404 (32%), Positives = 633/1404 (45%), Gaps = 101/1404 (7%)

Query: 4    AAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRH 63
            A P++ DVL LSPLQEGL       +D  D+Y  +  +D+ G +D   LR +   +L RH
Sbjct: 1526 AEPRLTDVLPLSPLQEGLLFHTAYDQDAEDVYITRLALDVRGDLDTGALRAAVTGLLTRH 1585

Query: 64   PNLRAAFWDRDVPKPVQIVPVHAALPWSE-------RVATPAEFDSIARSERRRPFDLSR 116
             +LRA+F       PVQ++   A LPW+E         A  AE D +   ER   FD  R
Sbjct: 1586 ASLRASFHRTAAGVPVQLIAAEAELPWTETDLSALDEPAQRAELDRLLVRERSLRFDPER 1645

Query: 117  GPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXX 176
             P LR  ++ + G+   R++F AHH+L+DGWS  V   EL  +                 
Sbjct: 1646 PPLLRFTLIKL-GDGHHRLLFAAHHLLLDGWSAPVLAGELFELYARRGDTSALPPVVPYK 1704

Query: 177  XYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSK--PGKTELLLPAADTARLR 234
             Y+ WL++QDR+A+   W   L G+ EP +VA  A AG +   PG+    LP   TA L 
Sbjct: 1705 DYLTWLSQQDRTASEDAWRTALAGIDEPTLVA-PAAAGHAAALPGRIVDELPPGLTAALT 1763

Query: 235  QWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPV 294
            + A   GLT+N  V  AW +VL+ LT R DV+FG  VSGRP +LPG+E+MVGLF N VPV
Sbjct: 1764 EAARARGLTMNAVVQGAWGLVLAGLTGRDDVLFGETVSGRPPELPGIESMVGLFSNTVPV 1823

Query: 295  VHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAI 354
               +    ++    T VQ +   +    YL L+++QR  G   LFD+  VFEN P D   
Sbjct: 1824 RVRIDPALSLADTLTGVQARRVELLAHHYLGLADLQRLAGLRTLFDTAVVFENFPADPGS 1883

Query: 355  RPATTPDGAQFLPVEMESLTHYPLTVV---SHLRXXXXXXXXXXXXXXXPYLPAAEIGER 411
            +   T  G     V+ +   HYPL +V      R                   A     R
Sbjct: 1884 Q--ETVHGLALSEVDTKGDNHYPLGMVVMQDDRRMVLNWYYRADLLDEELVASATRQLRR 1941

Query: 412  MLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXX 471
            +L      PD   G    L     AEL      A  SAP  D  V E+ E   Q      
Sbjct: 1942 VLDAFTTAPDTPVGRLGLLGDEETAELTTGS--AGVSAPPSDAVVGELIE--AQAARTPQ 1997

Query: 472  XXXXXXGVRH-TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXX 530
                  GV    YAEL+ RA RLA EL   G GPE +VA+ + RS               
Sbjct: 1998 AVALIDGVTELRYAELNERANRLAHELIHRGAGPERLVAVAMERSAELVVALLAVLKSGA 2057

Query: 531  XYLPVDVTLPSARVESIVRQASPALAI-TEADYSQLVGTAVPTLALDDPAAVESISRRSA 589
             YLPVD + P+AR+  ++  A P + + T +  + L      T+ +DD A    I+ R A
Sbjct: 2058 AYLPVDPSHPAARIGGLLDDARPGIVLTTRSAAATLPRHDADTVTVDDAATAAGIAARPA 2117

Query: 590  AAPT-VDRRPE----QSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXX 644
            A PT  DRR        AYVI+TSGSTG PKGVV  + +V+ Y        +        
Sbjct: 2118 ADPTDADRRSPLTAGNPAYVIYTSGSTGVPKGVVVEHRSVVDYLG------WTSLSYPGA 2171

Query: 645  XXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPS 704
                  H+  +SFD +   +   L      L  A  + +   L   +A   +  +  TPS
Sbjct: 2172 AGRALLHS-PVSFDLTVTALFTPLTVGGAVLIAA--LEEEPELSARLAGAPVTFMKATPS 2228

Query: 705  MFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQ----MAVYNCYGPTEMTVEXXX 760
                L A        + L LGGEA+   L + L G  +      V N YGPTE TV    
Sbjct: 2229 HLPLLGALPAAYSPTAELLLGGEAL---LGEALAGWRERHPDATVRNVYGPTEATVNVTE 2285

Query: 761  XXXKDYRKP------TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPG 814
                D   P       +G   A    YV DSALR V  GV GELYL+G  LARGY+GR G
Sbjct: 2286 FTI-DPGTPLAPGPVPMGRPQANVRAYVLDSALRPVASGVAGELYLAGPCLARGYLGRAG 2344

Query: 815  MTAARFVADPLRP-GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALR 873
            +T+ RF ADP  P G RMYRTGD+ RRL+ G   +VGRAD QVK+RG+RVE+GE+ AA+ 
Sbjct: 2345 LTSERFTADPYGPAGSRMYRTGDVARRLADGDLVFVGRADDQVKLRGHRVELGEVSAAVA 2404

Query: 874  GQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPR 933
              PGV   AV V    D   LV + V  D    D   LR  L + LP YMVP  +V L  
Sbjct: 2405 ALPGVAAQAVVVRDGADGGRLVAYAVPADGAAPDGQDLRRLLADTLPDYMVPDAVVVLDA 2464

Query: 934  LPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPH--IDDD 991
            LPV ++GKLD  AL      A  +V      +  T  E +LC LF + L+ +P   +DDD
Sbjct: 2465 LPVTSHGKLDRRALPEPEFTATAAVR-----APRTPQEEILCGLFGQVLD-LPEAGVDDD 2518

Query: 992  LFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAIDAAVD-SQDAPADADY 1049
             F  G +S+ A+ L+ + R   G  VD R V  A T  +L A +    D ++ APA    
Sbjct: 2519 FFELGGNSLSAVRLLSRVRSAFGSEVDVRAVFEARTPARLAALVGPGGDATRPAPAAGRR 2578

Query: 1050 GAVRPLPMVS---WLYEY--GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSI 1104
                PL       W  +   G    +   + +RL   +D  ++   +  ++D H++LR++
Sbjct: 2579 PDEIPLSFSQRRLWFLDRLDGASGAYNIPIGIRLRGTLDLDALRAAVADVVDRHESLRTV 2638

Query: 1105 LTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMV 1164
                   PR   ++P    A   +  +  PE S   L  A   AAR     ++P     V
Sbjct: 2639 FPAAGGKPRQSVQDPGTPLAPVEIVEVA-PERSAQALRRA---AARGFDLAVEPP--LRV 2692

Query: 1165 RAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILP---E 1221
                   T+H      +LLL  HH+A D  S   +  DL+ A+ +   G  P+  P   +
Sbjct: 2693 TLFVLGATDH------VLLLNVHHIASDGWSNAPLARDLSTAYTARHGGRAPRFAPLPVQ 2746

Query: 1222 FTSYRRWCELMWHRASAPQ--VQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRA 1279
            +  Y  W   +    S P+     Q  +W   +      L L    PT D     ++T  
Sbjct: 2747 YADYTLWQRELLGDESDPRSLAARQLAFWKESLAGAPAELAL----PT-DRPRPAEMTTE 2801

Query: 1280 AIPVDVT-----ERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHG 1334
               V+ T        L  + R   V   ++A   +A    R     D   G  VA    G
Sbjct: 2802 GATVEFTLDAGLHARLATLARTHQVSLFMVAQAGLAALLTRLGSGTDIPLGTAVA----G 2857

Query: 1335 RADAVLDTDTTNTVGWFTNAFPVR 1358
            R    L+    + VG+F N   +R
Sbjct: 2858 RPHESLE----DLVGFFVNTLVLR 2877



 Score =  451 bits (1159), Expect = e-124
 Identities = 371/1063 (34%), Positives = 494/1063 (46%), Gaps = 75/1063 (7%)

Query: 480  RHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTL 539
            R TY EL+ARA + A  L   G GPE  VA+ +PRS                +LPVD   
Sbjct: 3071 RMTYGELNARANQWAHYLISKGAGPERYVAVAVPRSADWPAITLGVLKTGAAHLPVDPGY 3130

Query: 540  PSARVESIVRQASPALAITEADYSQ---LVGTAVPTLALDDPAAVESISRRSAAAPTVDR 596
            P+ R+  IVR A PAL +   + +    L GT V   A+DD      +       PT   
Sbjct: 3131 PADRIAHIVRDARPALVVATGETATGPALAGTVVH--AVDDADVTARVDAAPVTDPTDRD 3188

Query: 597  RP-----EQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXH 651
            R      +  AYVI+TSGSTG PKGV+ T+  +      HAE                  
Sbjct: 3189 RDTPLGVDHPAYVIYTSGSTGLPKGVLVTHRGIAGMAGAHAENF------AIDTDSRVLQ 3242

Query: 652  AWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLS 710
            A S SFD S   + + LL+G  + L D       + L   +    +  +  T  +   + 
Sbjct: 3243 AVSPSFDVSMADLAMTLLNGATLVLPDTHHAPAGEELAALVDRHGVTHLQITAGVLATVP 3302

Query: 711  AAGLLDHNLSVLALGGEAINTGLWDQLRGLSQ-MAVYNCYGPTEMTV-EXXXXXXKDYRK 768
               L   +L  LA+GGEA      DQ+   S+   + N YGP+E TV             
Sbjct: 3303 RTAL--GSLRTLAVGGEACPP---DQVDHWSRGRRLLNVYGPSEATVCATMSRPLSGAVH 3357

Query: 769  PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-RP 827
            P IG     T  YV DS L  VP GV GEL+++G  LARGY+GRPG+TA RFVA P   P
Sbjct: 3358 PPIGAPLWNTRVYVLDSVLMPVPVGVAGELHIAGDGLARGYLGRPGLTAERFVAHPFGAP 3417

Query: 828  GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLR 887
            G+R+YRTGDLVR  + G   +VGRAD QVKIRG+RVE+GEIEAAL   PGV  AA ++ R
Sbjct: 3418 GERLYRTGDLVRWNTDGQLEFVGRADDQVKIRGFRVELGEIEAALVTHPGVTAAAAALHR 3477

Query: 888  QQD-RTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHA 946
              D R  LV   V       D  +L   L   LP YMVPA    +  LP+NANGK+D  A
Sbjct: 3478 GADGRDRLVACTVPSGAAPADAGELGDHLGRLLPEYMVPAAFTVVGALPLNANGKVDRTA 3537

Query: 947  LDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV-PHIDDDLFLFGMDSIVAISL 1005
               L E    S   G     + +T  +LCEL  + L+     +DD+ F  G DSIV+I L
Sbjct: 3538 ---LPEPDFGSRGEGREPRDAKET--LLCELIRDLLDIERVSVDDNFFALGGDSIVSIQL 3592

Query: 1006 VHKARRQGLRVDPRMVLTATTIRQLGAA------IDAAVDSQDAPADADYGAVRPLPMVS 1059
            V +A   GL      VL   T+ +L AA       D A  +  A  D   G V   P V 
Sbjct: 3593 VSRALEAGLEFTATDVLRHRTVGELAAAATGPEDADGASTAPAADDDRGVGEVGLTPYVH 3652

Query: 1060 WLYEYGN-YRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGP--RLVT 1116
             L   G        T +L LP   D + +  +L+ +LD HDTLR  LT         L  
Sbjct: 3653 ALRRRGGPVDSSAATAVLALPGDTDEARLHTVLRTVLDRHDTLRLRLTRRAGNLVWGLEV 3712

Query: 1117 REPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWF---RGTE 1173
            R      A D+LTR+ +   +  EL+   A A       + P  G ++RA+W     G E
Sbjct: 3713 RPRGETDARDLLTRVDVTGLTPGELSDETARATGTALAALAPEDGVVLRAVWLDGGPGGE 3772

Query: 1174 HRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMW 1233
            HR      LLL  H LA D  +W +++ DL  AW +  AGT  ++ P    YR W E   
Sbjct: 3773 HR------LLLAVHRLAADPQAWRVLVADLRTAWEA-AAGTGAQLPPAGADYRSWTERNA 3825

Query: 1234 HRASAPQVQDQRDYWAALVREPDPALGLRYP-DPTRDTWSTLQLTRAAIPVDVTERVLGA 1292
              A+AP++ D+   W  L+   D AL L  P DP RDT  T++     +    +  +L  
Sbjct: 3826 EAAAAPELLDELQTWTDLL-GADAALSLTGPLDPARDTRGTVRNVEVTLSAAESAALLNE 3884

Query: 1293 V--RRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGW 1350
            V  R   G +E+LL A A A+  W+  R    AAG L+ +E  GR     D+    T+G 
Sbjct: 3885 VPERFATGAQEVLLGALAAALEEWQVRRGLRTAAGTLIDVERDGRGG---DSGLDRTLGQ 3941

Query: 1351 FTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVD--GV 1408
            F    PVRLGAG AA           +A D V  V   L A+P DG  YG+LRY++   V
Sbjct: 3942 FALVHPVRLGAGEAAGG---------SAADQVKRVKELLAAVPGDGAGYGMLRYLNPQTV 3992

Query: 1409 AELVDAVDPQIQFSYLGRLDLG-GVADQPWSLLTGPYLDALPIDPE-PDLPLRFALNLSV 1466
            + L  +  PQ++F++ G      G    P  +  G      P   E P+ P  + L +  
Sbjct: 3993 SLLAPSPFPQLRFAHRGTFPAPLGDGSTPLVVAGG----VRPAGAEAPETPAEYPLEVET 4048

Query: 1467 FVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            +     EG +L   W W DA+   +D+  L   W+     L A
Sbjct: 4049 WADEGPEGVRLTARWSWPDALLSEADVTELADSWRDAARRLLA 4091



 Score =  271 bits (692), Expect = 7e-70
 Identities = 186/553 (33%), Positives = 267/553 (48%), Gaps = 16/553 (2%)

Query: 966  ASTDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTA 1024
            A    E VL  LF E L+A    +DDD F  G DSIV+I L  +AR+ GLR+  R V   
Sbjct: 4589 ADPSRESVLAGLFAELLDAPEVGLDDDFFELGGDSIVSIQLAGRARKAGLRISLRDVFKH 4648

Query: 1025 TTIRQLGAAIDAAVDSQDAPADADYGAVRPL-PMVSWLYEYGNYRRFTH-TVLLRLPSGI 1082
             T+R L        D     + A+     PL P++  LYE G      H   LL++P+  
Sbjct: 4649 RTVRSLARIATEDEDPAAGRSAAEAVGEMPLTPVMLDLYERGGPTDSVHQAALLQVPADA 4708

Query: 1083 DRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELA 1142
            D   +   LQ +LD HD LRS +    +G RL      +V A  +L R  +     D L 
Sbjct: 4709 DEKRLAATLQAVLDHHDILRSRIVRGADGLRLEVTPTGSVDASALLRRRDITSVPRDGLI 4768

Query: 1143 SAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGD 1202
              V         ++    G MVRA+WF      ADP  +L+L  HHLAVD VSW ++  D
Sbjct: 4769 GLVTEEQVRAQSELSCEDGEMVRAVWFDAGP--ADPGRLLILV-HHLAVDGVSWRVLQED 4825

Query: 1203 LAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLR 1262
            L   W ++     P + P  TS+R W  ++  +A+ P+   + D W +++   DP L  R
Sbjct: 4826 LRQVWEAVSQDREPGLEPVGTSFRHWATVLAEQAAGPERSKELDLWRSVLETADPLLSER 4885

Query: 1263 YPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRR--DQGVRELLLAATAMAVASWRRVRAQ 1320
              DP  D   T +     +P + +E +LG V    +  V E+LL A A+AVA WR  R +
Sbjct: 4886 PLDPAVDVVRTARRLTVTLPPEFSEPLLGTVPAAFNAAVDEVLLTALALAVARWRSGRGR 4945

Query: 1321 DPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQD 1380
               + +LV LEGHGR + V   D + TVGWFT+ +PV +  GAAA    +A+ + +    
Sbjct: 4946 GDGSELLVGLEGHGREEIVPGADLSRTVGWFTSVYPVAIDPGAAARPGSEADAEVLGT-- 5003

Query: 1381 LVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQFSYLGR---LDLGGVADQ 1435
             +  V   L AIP+ G+ YGLLR++  D   EL    +PQI F+YLGR   +D       
Sbjct: 5004 ALKRVKEQLRAIPDKGMGYGLLRHLNPDTGPELAGFAEPQIGFNYLGRFKAVDARARRAD 5063

Query: 1436 PWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDH 1495
             W+       + L        PL  ++ LS       +G +L+  W W  A+F+  ++  
Sbjct: 5064 DWA-APPEATETLGGGGADSAPLAHSIGLSAVAQDRPDGVRLVAIWSWPGALFDEDEVRA 5122

Query: 1496 LTGLWQRGIAALA 1508
            L  LW   + ALA
Sbjct: 5123 LADLWFGALEALA 5135



 Score =  245 bits (626), Expect = 3e-62
 Identities = 148/383 (38%), Positives = 205/383 (53%), Gaps = 12/383 (3%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDG-VDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPN 65
            +++DVL L+PLQEGL   H L + G +D+Y++QF +D++G    E+LR S +A+LDRH N
Sbjct: 4123 RLDDVLPLAPLQEGLL-FHSLYDRGEIDVYTVQFGLDLEGDPRTEVLRASVRALLDRHEN 4181

Query: 66   LRAAFWDRDVPKPVQIVPVHAALPWSER-------VATPAEFDSIARSERRRPFDLSRGP 118
            LRA F    + +PVQ +P    LPW E         A  AE D +   ER   FDL R P
Sbjct: 4182 LRAGFAHEHLSRPVQFIPAETGLPWHEEDLSGLDATARGAEVDRVMCRERAERFDLDRPP 4241

Query: 119  ALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY 178
             LR  +L + G  + R++ T HH+L+DGWS  +   EL+ +                  Y
Sbjct: 4242 LLRCTLLRLGGG-RARLVLTFHHLLLDGWSTPILLDELMRLYAAGGDPSGLPPAHPYRGY 4300

Query: 179  IVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQS-KPGKTELLLPAADTARLRQWA 237
            + WL  QDR+ +   W   L    EP ++A      ++    K  +   A   A L   A
Sbjct: 4301 LSWLDGQDRTVSEQAWRQVLDPSVEPTLLAPADPERRAVATDKVSVTFGADVVAGLTALA 4360

Query: 238  GRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHY 297
            GRHG T NT V  AW ++L+RL  R DVVFG  VSGRP ++PGVE MVGLFIN VPV   
Sbjct: 4361 GRHGTTANTVVQAAWGLLLARLAGREDVVFGATVSGRPPKVPGVERMVGLFINTVPVRVA 4420

Query: 298  VSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPA 357
                E +     ++ +Q   +    +  L ++QRE G+G LFD+L VF+N P D A    
Sbjct: 4421 FRPGEPIGDALARLWQQQVELTAHQHARLVDLQREVGKGELFDTLLVFQNIPADGA-GFG 4479

Query: 358  TTPDGAQFLPVEMESLTHYPLTV 380
               D  + + +EM   THYPLT+
Sbjct: 4480 GDADRVRAVDLEMNDATHYPLTL 4502


>tr|C1AZY4|C1AZY4_RHOOB Tax_Id=632772 SubName: Full=Putative
             non-ribosomal peptide synthetase;[Rhodococcus opacus]
          Length = 11247

 Score =  717 bits (1851), Expect = 0.0
 Identities = 517/1556 (33%), Positives = 751/1556 (48%), Gaps = 90/1556 (5%)

Query: 6     PQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPN 65
             P   DV  L+PLQ G+F    LAED VD+Y+ Q V+D  G VD   LR +A+A++ RH N
Sbjct: 9722  PAATDVWPLAPLQSGMFFHSVLAEDAVDVYTAQVVLDFRGVVDTGRLRGAAEALIARHAN 9781

Query: 66    LRAAFWDRDVPKPVQIVPVHAALPWSER-VATPAEFD------SIARSERRRPFDLSRGP 118
             LR AF   D    VQ+V     LPW E  ++  +E D      S+    R   FD+ R P
Sbjct: 9782  LRTAFVPDDSGTAVQVVVDRVELPWEELDLSALSEADREERISSVLSEHRSARFDMGRPP 9841

Query: 119   ALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY 178
              +R +++   GE+  R   + HHIL+DGWS+ +   +LL +                  +
Sbjct: 9842  LMRFLLIRT-GESSYRFSISNHHILLDGWSMPLLMKDLLVLYATRGDGSVLPRVRGYRDF 9900

Query: 179   IVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTA--RLRQW 236
             + WL+++D +A+ + W   L G+  P ++A  A  G+ +P   E  L   +     L + 
Sbjct: 9901  LTWLSERDANASRSAWAHALAGLDGPTVLA-PAPGGEGRPEPAEFALHLGEVVSENLARI 9959

Query: 237   AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
             A   GLT+NT V  AW ++L+R+T   DVVFG  VSGRP ++ G+E+MVGLFIN +P+  
Sbjct: 9960  ARDRGLTMNTIVQAAWGLLLARMTASDDVVFGATVSGRPPEVAGIESMVGLFINTIPIRV 10019

Query: 297   YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDA-IR 355
              V   E+++    ++Q + SA+ D  ++ L EIQ+  G G LFD+L VFE+ P+D A + 
Sbjct: 10020 RVDPRESILGLLERLQAEQSALFDHHHIGLPEIQQIAGIGGLFDTLTVFESYPVDRAGLT 10079

Query: 356   PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLP-------AAEI 408
               +  DG +   V++   +HYPL++++                   YLP          +
Sbjct: 10080 EDSDIDGLRVAGVQISDASHYPLSLLAQ--------SDSELQLVLKYLPDVFGAETVERL 10131

Query: 409   GERMLTVLRQLPDIGDGTPDDLDIRTAAE--LKAHGLLAARSAPTFDTTVWEMFERQVQX 466
             G R+  +L+ +         DLD+    E  L   G   + S    + +V  MF  QV  
Sbjct: 10132 GSRLNRILQTIAAGSSTLVGDLDLLAPDERDLVLSGWNDS-SRDVAEESVVSMFGAQVAR 10190

Query: 467   XXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXX 526
                         VR TYAE  AR  RLA  L   GVGP+TVV + + RS           
Sbjct: 10191 TPDRTAVVADH-VRLTYAEFDARVNRLARHLIAMGVGPDTVVGIAMRRSLDMLTSLYAVH 10249

Query: 527   XXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDD-------PA 579
                  Y+P+D   P+ R   +V  A+P   ++ AD    +   VP   ++D         
Sbjct: 10250 AAGGAYVPIDPEHPADRTSYVVDSATPTCVLSSADDIANLDVDVPVYLVEDFDLSGYGDG 10309

Query: 580   AVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXX 639
              VE   R        + RP   AY ++TSGSTG PKGV   ++A+ +  A      +   
Sbjct: 10310 PVEDTERLG------ELRPHNLAYALYTSGSTGRPKGVAIPHSALANQLA------WMRD 10357

Query: 640   XXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDM 698
                             +FDAS W+  + L+ G  + +   +  RD + +   +    + +
Sbjct: 10358 VYGIDAQDVVLQKTPFTFDASVWELFLPLVVGGTLVIASPDGHRDPEYMAATVDTESVTV 10417

Query: 699   IDTTPSMFVQLSAAGLLD--HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV 756
             I   PS+      A   D   +L ++  GGE +     +++ GL    + N YGPTE+T+
Sbjct: 10418 IQFVPSVLTMFLDAVTADGCGSLRLVFAGGEPLPQSAAERVAGLGSAELVNLYGPTEVTI 10477

Query: 757   EXXXXXXKDYRKPT---IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRP 813
                    +     T   IG+    T  YV D+ L   P GV GELYL GAQLARGYV   
Sbjct: 10478 NSTAHVVELSGTATIAPIGSPAWNTRAYVLDAHLNPAPIGVPGELYLDGAQLARGYVNSA 10537

Query: 814   GMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
              ++A RFVA+P   PG RMYRTGDLVR    G   +VGR D QVK+RG R+E+GE+E A 
Sbjct: 10538 ALSAERFVANPFGDPGVRMYRTGDLVRWNEGGVLEFVGRTDFQVKVRGLRIELGEVEEAF 10597

Query: 873   RGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLP 932
                  V  AAV V   +    LV +VV + +   D   L A + E LP YM+P  ++ L 
Sbjct: 10598 VRHGDVAQAAVIVHNSEVGARLVAYVVPRPDSAIDQAALNAFVAESLPEYMIPDSVMVLA 10657

Query: 933   RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDD 991
              LP+  +GKLD  AL           S        TDTER L  +F E L      IDD 
Sbjct: 10658 ELPLGTSGKLDRRAL-----PVPDFASAAEFRPPRTDTERALASVFGELLGRESIGIDDS 10712

Query: 992   LFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGA 1051
              F  G DSIV+I LV +AR  G+    R V    T+ +L A  D+   +  A A+ D G 
Sbjct: 10713 FFELGGDSIVSIQLVARARAAGIHFTARDVFERRTVAELAAVADSGESAAAALAEYDGGG 10772

Query: 1052  VRPLPMV----SWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTE 1107
             V  +P+       +   G++ RF   +LL LP+GIDR  +   +  ++D HD LRS L  
Sbjct: 10773 VGTVPLTPVARKMVERGGDFDRFVMPLLLTLPAGIDREQVLATISAVVDQHDVLRSTLVT 10832

Query: 1108  TPEGPRLVTREPAAVRAEDVLTRITLPEGSD------DELASAVAHAARVVTDQIDPSAG 1161
                   L      +V  +  + R+ +  G++      D +A A   AA    D++DP  G
Sbjct: 10833 GGAEDALEIAPAGSVDLDATVQRVEIAAGAEPGSPEFDAVAGAAFDAA---LDRLDPRTG 10889

Query: 1162  AMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPE 1221
             +M++ +WF   E  AD    LL+  HHL +D VSW I++ D A A   + AGT P + P 
Sbjct: 10890 SMLQFVWFDPAE--ADRRGRLLVVPHHLVIDSVSWRILVPDFATAGAQIAAGTTPSLEPV 10947

Query: 1222  FTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAI 1281
              TS RRW + +   A+ P+   +   W  ++  PDP LG R  D + D  STL+  R  +
Sbjct: 10948 GTSLRRWTDGLLEAAATPERVAELAVWERMLTGPDPLLGSRELDLSADLVSTLERARVDV 11007

Query: 1282  PVDVTERVLGAV--RRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRAD-A 1338
             P  VTE +L       D  + ++L AA A+AVASWRR R  + A+  +V LEGHGR + A
Sbjct: 11008 PAPVTEALLDGTPGALDGEIGDVLAAALALAVASWRRDRGVE-ASSTVVTLEGHGREESA 11066

Query: 1339  VLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLD 1398
             V   D + TVGWFT  +P RL      +DI  A      A D V +V   L AIP+ G+ 
Sbjct: 11067 VPGADLSRTVGWFTTMYPARL--DLTGIDIADAMSGGAGAADAVRAVRDQLSAIPDRGIG 11124

Query: 1399  YGLLRYV--DGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPID---PE 1453
             YGLLRY+  D  A +    +PQI F+Y+GR+    V +    L   P  ++ P+     +
Sbjct: 11125 YGLLRYLNPDTPAVMRKWSEPQIVFNYIGRVSAAEVPEAVRGLDWLPDFES-PVTGGFEK 11183

Query: 1454  PDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
               +P +  L++   +  T EG QL     +   +    D+D     W   + AL A
Sbjct: 11184 SAMPAQAVLDIQSVISETTEGLQLSAFMSFPPGILSAPDVDRFGEFWVAALTALVA 11239



 Score =  504 bits (1298), Expect = e-140
 Identities = 430/1402 (30%), Positives = 644/1402 (45%), Gaps = 97/1402 (6%)

Query: 6    PQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPN 65
            P + DV +L+PLQ GL     LA    D+Y+ Q V+D+ G VD   LRR+A++++ RHPN
Sbjct: 1548 PALADVWSLAPLQVGLLFHASLAGTATDVYTTQLVMDLGGSVDTGRLRRAAESLVARHPN 1607

Query: 66   LRAAFWDRDVPKPVQIVPVHAALPWSE----RVATP---AEFDSIARSERRRPFDLSRGP 118
            LR AF   D    +Q+V     +PW+       + P   AE D++  + R   FD++  P
Sbjct: 1608 LRTAFVAGDDGTGMQVVVDRVDVPWTHVDLSAASEPDRDAELDALMLANRTDRFDMTAPP 1667

Query: 119  ALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY 178
             +R +++   G  + R   T HHIL+DGWSL +   +LL +                  Y
Sbjct: 1668 LVRFLLVET-GADRYRFAVTNHHILLDGWSLPILIQDLLTLYAVDGDALALPQPRPYRSY 1726

Query: 179  IVWLAKQDRSAALAGWMDYLRGVSEPLMVA--YEATAGQSKPGKTELLLPAADTARLRQW 236
            + WL+ QD   ++A W   L G+ EP ++A  +  TA    PG+  + LP    A +   
Sbjct: 1727 LEWLSAQDPQVSVAAWAKALGGLEEPTLLAPAHTETAPALTPGELVIDLPDDLLADMTAR 1786

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A   G+T+NT V  AW +VL RLT R DVVFGT VSGRP Q+PG+E+M+GLFIN +PV  
Sbjct: 1787 ARELGVTMNTLVQAAWGIVLGRLTGRDDVVFGTTVSGRPPQVPGIESMLGLFINTLPVRV 1846

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPID-DAIR 355
             V   +AV     ++Q + + + D  ++ L++IQ+  G G LFD+L V+E+ P+D +A+ 
Sbjct: 1847 RVQAGDAVRTLLDRIQHEQTELLDHHHVGLTDIQQGLGLGALFDTLMVYESYPLDREALT 1906

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLP----AAEIGER 411
              +  +G + L V     THYPL +V+                   +LP    AAE+ + 
Sbjct: 1907 KNSDIEGLRVLDVTSNDATHYPLAIVA--------MTDPRLHLTAKFLPELFEAAEVEKI 1958

Query: 412  MLTVLRQLPDI-GDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXX 470
            M  V+R L  + GD      DI   A  +   LLAA      D                 
Sbjct: 1959 MARVVRVLGALSGDVDTRVADIDILAPDERASLLAAHGTEAADPLSLPEILAATAAEHGE 2018

Query: 471  XXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXX 530
                   G   TYAEL AR+ RLA  L + GVGPET VAL + RS  S            
Sbjct: 2019 RIALVADGESMTYAELDARSSRLARVLIDRGVGPETSVALGMTRSLHSVVGTWAVAKAGG 2078

Query: 531  XYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAA 590
             ++PVD   PS R+  +V  +   L +T +     + + V  LALD  +  ES+    + 
Sbjct: 2079 AFVPVDPRYPSERIAHMVADSGAVLGLTVSAQRNDLPSGVDWLALDS-SECESLCAPKSP 2137

Query: 591  APTVDR------RPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXX 644
             P  D       + E +AY+I+TSG+TG PKGVV T+  + ++ A+              
Sbjct: 2138 EPVTDSERTTAVQLEHAAYMIYTSGTTGLPKGVVVTHTGLANFSAEQRTH------YGVS 2191

Query: 645  XXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPS 704
                  H  S SFDAS   ++         +    ++   + L   +A  ++     TP+
Sbjct: 2192 PSARTLHFASPSFDASVLELLLAFGCGATMVVAPADLFGGEELRNFLADNEVTHAFVTPA 2251

Query: 705  MFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV-EXXXXXX 763
                +  AGL    L V+ +GGEA    L +  R      +YN YGPTE TV        
Sbjct: 2252 ALASVEPAGL--DRLEVVVVGGEACPPELVE--RWAPGRRMYNGYGPTEATVMSNVSNML 2307

Query: 764  KDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVAD 823
                +  IG        YV D+ LR VP GV GELY++G  LARGY  R G+T+ RFVA+
Sbjct: 2308 VPGNRIEIGGPVCAVTVYVLDALLRPVPVGVAGELYIAGPGLARGYHDRLGLTSERFVAN 2367

Query: 824  PL-RPGQRMYRTGDLVRRLSHGGY------AYVGRADTQVKIRGYRVEVGEIEAALRGQP 876
            P    G RMYRTGD+VR +   G+       YVGR+D QVK+RG+R+E+GEI+AAL   P
Sbjct: 2368 PFGENGSRMYRTGDVVRFVLDPGHRAGYGVEYVGRSDFQVKVRGFRIELGEIDAALAAHP 2427

Query: 877  GVHDA-AVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLP 935
             +  A  +        T+LV +V+       D+ ++   + + LP++MVP+ IV L  +P
Sbjct: 2428 DLEFAVTLGTSLPSGSTALVSYVLPTAGAAVDVAEVTHFVGDTLPAHMVPSAIVVLDEIP 2487

Query: 936  VNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFL 994
            +   GKLD  AL     DAL     G  V   T TE ++  +  + L  A   + +  F 
Sbjct: 2488 LTTAGKLDRKALPEPDFDALQ----GEMVEPRTPTEELVAGVLADVLGLAKISVAESFFD 2543

Query: 995  FGMDSIVAISLVHKAR-RQGLRVDPRMVLTATTIRQLGAAI-DAAVDSQDAPADADYGAV 1052
             G +S+VA   V +     G R+  R +  A T+ +L   + + A    D PA       
Sbjct: 2544 LGGNSLVATKAVARLNAAAGTRLGVRELFEAPTVERLAVKVAEQAGTGSDRPALVARPRP 2603

Query: 1053 RPLPM-----VSWLYEYGNYRRFTHTVLL--RLPSGIDRSSIELMLQLLLDGHDTLRSIL 1105
              +P+       WL    +     + + L  RL   +D  ++   +  +L  H++LR++ 
Sbjct: 2604 ERVPLSMAQQSMWLMNRFDTASSAYNIPLAVRLSGALDIDAMSSAVSDVLARHESLRTVF 2663

Query: 1106 TETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVR 1165
             ++ +GP     + A V  +  LT + +PE    EL +A+   A    +  D +    +R
Sbjct: 2664 PDSADGPYQQVVDVAQVPFD--LTPVRVPEA---ELHTALTEFA---AEGFDVTVAPPLR 2715

Query: 1166 AIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSY 1225
               F      +D   +L+L  HH+  D  S   +  D+  A+ +  AG  P   P    Y
Sbjct: 2716 IRLFA----TSDTEFLLVLVVHHICADGASMAPLARDVMVAYSARTAGAAPLWQPLPVQY 2771

Query: 1226 RRWCELMWHRASAPQVQD-------QRDYWA-ALVREPDPA-LGLRYPDPTRDTWSTLQL 1276
              +   +W R       D       Q  +WA  L   P+   L L +  P R +     +
Sbjct: 2772 PDFA--LWQRDVLGDPADTQSLAGKQIAHWADTLAGAPELIDLPLDHIRPARQSMRGDSI 2829

Query: 1277 TRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRA 1336
              A  P       L AV +D+G    ++   A+     R   + D   G  +A     R 
Sbjct: 2830 DFAITP--ELRHGLEAVGKDRGASLFMVTHAALTTLLSRLSSSDDITVGTPLA----ARG 2883

Query: 1337 DAVLDTDTTNTVGWFTNAFPVR 1358
            D  LD    + VG F N   +R
Sbjct: 2884 DQALD----DLVGMFVNTLVLR 2901



 Score =  493 bits (1268), Expect = e-136
 Identities = 427/1349 (31%), Positives = 606/1349 (44%), Gaps = 106/1349 (7%)

Query: 225  LPAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETM 284
            LP +    L +  G    +    V+ A+A  L+ +TDR DVV    VS R      +   
Sbjct: 205  LPESTATLLDEALGGSNASSAPVVVAAFAAYLAHMTDRTDVVLSLPVSARTTAT--LRRS 262

Query: 285  VGLFINAVPVVHYVSGTEAVVAQCTQVQRQ-SSAMRDVSYLSLSEIQREHG-----RGPL 338
             G+  N VP+   ++    V      VQ + + A+R   Y    +I+R+ G     RG  
Sbjct: 263  GGMVSNIVPLRLQITPEMTVPELVKSVQIELTGALRRQRYRH-EDIRRDAGAPQGQRGFF 321

Query: 339  FDSLFVFENAPIDDAIRPATTPDGAQFL---PVEMESLTHYPLTVVSHLRXXXXXXXXXX 395
              S+ +         I+  T       L   PVE  SL  Y     S +           
Sbjct: 322  GPSINIMM---FHSEIKLGTVTGHQNVLTTGPVEDLSLNIYQGVAGSKIHIDFEAN---- 374

Query: 396  XXXXXPYLPAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAH-------GLLAARS 448
                 P L +A+  +R  +      +   G  DD  +   A +          G      
Sbjct: 375  -----PNLYSADELDRHHSRFFDFFERFLGAGDDASVSDLATMSGEEYEQVVTGWNGDVV 429

Query: 449  APTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVV 508
            AP   T V ++F+ QV             GV  TYAE  AR  RLA  L   GVGPET V
Sbjct: 430  APPAGTVV-DLFDAQVARTPDATALVFE-GVELTYAEFDARVNRLARTLIGRGVGPETKV 487

Query: 509  ALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGT 568
            AL + RS  S             Y+P+D   P+ R   ++  A P   +  +        
Sbjct: 488  ALAIRRSLDSMVAMYAVVKAGAAYVPLDPDHPAERTAYVLESARPLCILAVSRDGLTFPA 547

Query: 569  AVPTLALD-------DPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTN 621
            A   + +D       D   +    R++A       R    AYVI+TSGSTG PKGV  ++
Sbjct: 548  AHDVVEIDALDATGVDAGPIRDEERKAAL------RAANPAYVIYTSGSTGRPKGVAVSH 601

Query: 622  AAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEE 680
            AAVL+     A R                     +FD S W+    L  G  + +   E 
Sbjct: 602  AAVLNQVTWIASRY------GLDANDVVLQKTPTTFDVSVWELFAALGSGSRLVIAAPEG 655

Query: 681  MRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDH--NLSVLALGGEAINTGLWDQLR 738
             RD   L + IA   +      PSM     +    +   +L V+ + GEA    +    R
Sbjct: 656  HRDPAYLADVIARQNVTATSFVPSMLSVFVSEADREQLVSLRVVLVAGEAFPPAVAAAFR 715

Query: 739  GLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTI--GTANAGTFGYVFDSALRMVPDGVVG 796
              S   ++N YGPTE TV             TI  GT    T  YV D  LR  P G  G
Sbjct: 716  AKSGAELHNLYGPTEFTVHATAGEVDRESVHTIPIGTPVWNTEAYVLDGHLRPAPIGSAG 775

Query: 797  ELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQ 855
            ELYL+GAQ+ARGY GRP +TA RFVA+P    G R+YRTGDLV+    G   Y+GR D Q
Sbjct: 776  ELYLAGAQVARGYEGRPELTAERFVANPFGAAGTRLYRTGDLVKWGVDGSIEYLGRTDFQ 835

Query: 856  VKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGL 915
            VK+RG R+E+GEIE+A+   P V  + V V        LVG+VV +     D+  L   +
Sbjct: 836  VKVRGLRIELGEIESAMSSYPHVAQSVVVVHDSSLGQRLVGYVVPESGSVVDVDDLTVHV 895

Query: 916  TERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLC 975
               +PSYMVP  ++ L  +PV A+GKLD  AL     +   +      V+  +  E  + 
Sbjct: 896  GRAVPSYMVPDAVMVLAEMPVGASGKLDRKAL----PEPTFAAESSEYVAPRSTMEESIA 951

Query: 976  ELFEEQLNAVPH--IDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAA 1033
             LF E L  +P   I D  F  G DSIV+I LV +A+  G+    R V    T+  L   
Sbjct: 952  GLFAEVL-GLPRVSIGDSFFALGGDSIVSIQLVSRAKEAGVLFTARDVFERKTVASLAEV 1010

Query: 1034 IDAAVDS-----QDAPADADYGAVRPLPMVSWLYEY-GNYRRFTHTVLLRLPSGIDRSSI 1087
              +A +S     ++ P  A  G +   P+V W+ E  G++ RF+ ++LL LP  ++R  +
Sbjct: 1011 AKSASESTVHVLEELPG-AGIGTMPLTPVVHWMTELGGDFHRFSQSILLALPPKVERERL 1069

Query: 1088 ELMLQLLLDGHDTLRSIL--TETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAV 1145
               L  ++D HD LRS L   ++P G  L      +V  + ++ R+   +G       A+
Sbjct: 1070 VRTLTAVVDRHDALRSSLRRNDSPAGWSLEVAPIGSVDVDRLVDRVEFTDGPGTGTFEAL 1129

Query: 1146 -AHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPA------------------NILLLTA 1186
             AHA     D++DP+ G++VR +WF   E  A+PA                    LL+  
Sbjct: 1130 AAHALERTVDRLDPATGSVVRFVWFAPAEDSAEPAPRDAADGDTVEAESAPQTGRLLVVI 1189

Query: 1187 HHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRD 1246
            HHLAVD VSW +++ D A+AW  + AG  P +    TS RRW   +   A + +   +  
Sbjct: 1190 HHLAVDGVSWRVLVPDFASAWGQIAAGADPLLPAVGTSVRRWAHGLADNARSARRVGELG 1249

Query: 1247 YWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRR--DQGVRELLL 1304
            YW   +   DP +G R  D  RDT ST    R  +P DVT+ +L  V R    GV + LL
Sbjct: 1250 YWRTTLDGADPLIGSRALD-GRDTVSTTGRVRLEVPADVTDGLLTDVPRAFHGGVNDGLL 1308

Query: 1305 AATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL-DTDTTNTVGWFTNAFPVRLGAGA 1363
             A A+AVA+WR  R    ++  LV LEGHGR + VL   D + TVGWFT+ FPVRL   A
Sbjct: 1309 TALALAVAAWRAERGFGESS-TLVHLEGHGREETVLPGADLSRTVGWFTSMFPVRL--SA 1365

Query: 1364 AAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAV--DPQIQF 1421
              VD+  A     AA   V S+   L  +P  G+ YG+LR+++     V A    PQI F
Sbjct: 1366 PGVDVRDALTGGSAAGQAVKSIKEQLARVPEHGIGYGMLRFLNAETRAVLAALPSPQISF 1425

Query: 1422 SYLGRLDLGGVADQPWSLLTGPYLDALPI--DPEPDLPLRFALNLSVFVGVTAEGTQ-LI 1478
            +YLGR+ +G +     +    P  D + +      ++P+ FAL+++  + V  EG Q L 
Sbjct: 1426 NYLGRVSVGEIPAAFRAAGWVPDTDTMELTGTRNSEMPVHFALDINAMI-VDVEGEQRLS 1484

Query: 1479 GNWRWSDAVFERSDIDHLTGLWQRGIAAL 1507
                +   V   S++  L GLW R +  L
Sbjct: 1485 ATVDFPQGVLAESEVGELAGLWTRALEGL 1513



 Score =  436 bits (1121), Expect = e-119
 Identities = 343/1069 (32%), Positives = 507/1069 (47%), Gaps = 71/1069 (6%)

Query: 482  TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPS 541
            TY EL  R+ RLA  L   G+G +  VAL L RS  S             ++PVD + P 
Sbjct: 8649 TYRELDERSNRLARVLIGRGIGADDFVALALTRSVESILSIWAVAKTGAAFVPVDPSYPF 8708

Query: 542  ARVESIVRQASPALAITEADYSQLVGTAVPTLAL-----DDPAAVESISRRSAAAPTVDR 596
             R+  +V  +   + +T   +   +   V  L L     DD  A  S    + A      
Sbjct: 8709 DRIMHMVTDSRVEIGLTTGAHVGELPDTVRWLVLGGDEMDDACASVSNDAVTDADRIRPT 8768

Query: 597  RPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLS 656
            R + +AYVI+TSGSTG PKGVV T+  + +   +  ER+               H  S S
Sbjct: 8769 RVDDAAYVIYTSGSTGLPKGVVVTHTGLANVTTEQVERL------RLTPQSRVLHFASPS 8822

Query: 657  FDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLD 716
            FDAS   ++  +      +  +  +   D L   +   ++     TP+    +  AGL  
Sbjct: 8823 FDASVFELLHAVAAASTMVIASGVVYGGDELARLLKKQKVTHAFITPAALTTVDPAGL-- 8880

Query: 717  HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKP-TIGTAN 775
              + VL++ GEA    L  +     +M  +N YGP+E T+           +P TIG   
Sbjct: 8881 ERVEVLSVAGEACPPELMQKWAPGRRM--FNLYGPSEATIWSTSSNPMRADRPVTIGGPT 8938

Query: 776  AGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLR-PGQRMYRT 834
             G    V DS L  VP GV GELY++G  +ARGY  R  +TA RFVA+P   PG+R+YRT
Sbjct: 8939 RGVDVVVLDSRLTPVPVGVAGELYVAGPSVARGYHNRFALTAERFVANPFGGPGERLYRT 8998

Query: 835  GDLVRRLSHGGYA-----YVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQ 889
            GD+VR +           YVGR+D QVK+RG+R+E+GEI+A L   P V D AV++   +
Sbjct: 8999 GDVVRWVHDDETGDLVLDYVGRSDFQVKVRGFRIELGEIDAELGRHPSV-DFAVTLGHHR 9057

Query: 890  DRTS---LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHA 946
            ++T    LV +V+       D+ +L A ++E LP YMVP+ I+ +  +P+   GKLD  A
Sbjct: 9058 EQTGQTVLVSYVMPAAGASIDVAELSAFVSETLPGYMVPSSIMAIDSVPLTPAGKLDRKA 9117

Query: 947  LDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIVAISL 1005
            L    E    SV+     + ST  E+ + ++F + L      +DD  F  G DSIV+I L
Sbjct: 9118 LP---EPQFVSVAS-EYTAPSTPMEKAIADVFAQVLGVDRVGVDDSFFALGGDSIVSIQL 9173

Query: 1006 VHKARRQGLRVDPRMVLTATTIRQLG--AAIDAAVDS---QDAPADADYGAVRPLPMVSW 1060
              +A+  G+    R V    T+  L   AA    VDS   ++ P     G +   P+  W
Sbjct: 9174 TTRAKNAGVLFTARDVFERKTVAALADVAAWATEVDSVKLEELPGGG-VGTMPLTPIAHW 9232

Query: 1061 LYEY-GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREP 1119
            L E  G + +F+  VLL  P  + R  +   +  +L  HD LRS LT   +       E 
Sbjct: 9233 LVETAGTFEKFSQAVLLTTPPAVTRDQLADTVDAILARHDILRSRLTRVGDDWSF---ES 9289

Query: 1120 AAVR----AEDVLTRITLPEG-SDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEH 1174
             +VR    A++++ +I   +    DE       A     D++DP+AG M + +WF   E 
Sbjct: 9290 LSVRRAFDADELIEQIEFTDKPGTDEFERLARAALDRAADRLDPAAGRMTQFVWFAPAES 9349

Query: 1175 RADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWH 1234
                +  LL+ AHHL VD VSW ++L D A A   + AG P ++ P  +S R W   +  
Sbjct: 9350 LPGQSGRLLVLAHHLVVDGVSWRVLLPDFATAGSQIMAGAPAQLEPVGSSVRAWAHGLAE 9409

Query: 1235 RASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVR 1294
             A +P    + D+W  ++   DP +G R  DP RD  +            VT+ +L  + 
Sbjct: 9410 EAKSPHRVAELDFWRGMLAGTDPLIGRRAFDPERDVIARTDRLSMTFSTQVTQALLTTIP 9469

Query: 1295 R--DQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADA-VLDTDTTNTVGWF 1351
            +  + GV + LLAA A+AV+ WR +R       VL+ LEGHGR ++ V   D   TVGWF
Sbjct: 9470 QSVNGGVNDGLLAALALAVSRWRELRGGTTDRSVLINLEGHGREESTVPGADLARTVGWF 9529

Query: 1352 TNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVA 1409
            T+ +PVRL    A  D+  A     +A   + +V   L A+P+ G+ YGLLRY+  +   
Sbjct: 9530 TSLYPVRLDVSRA--DLADAFDGGASAGSALKAVKEQLLAVPDKGIGYGLLRYLNDETAP 9587

Query: 1410 ELVDAVDPQIQFSYLGRL----------DLGGVADQPWSLLTGPYLDALPIDPEPDLPLR 1459
             L     PQI F+YLGR           DLG + D      +G +  A+  D E   P  
Sbjct: 9588 ALASLPTPQIGFNYLGRAGSVDLPAEIRDLGWIPDSD----SGEFGGAM--DDEMVAPA- 9640

Query: 1460 FALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
              L+++     TA G Q+     ++  + + +D+     LW     ALA
Sbjct: 9641 -VLSINAVTSETASGPQIEAKIAFATEILDEADVWEFAELWHAAATALA 9688



 Score =  357 bits (915), Expect = 9e-96
 Identities = 420/1559 (26%), Positives = 657/1559 (42%), Gaps = 141/1559 (9%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            + LS  Q+ ++ ++Q  +     Y++   V + G +D   L  +   +++RH +LR  F 
Sbjct: 6043 IPLSLAQQRMWFVNQF-DPSSPAYNLPLAVRLTGSIDPAALNSAWADVVERHESLRTVF- 6100

Query: 72   DRDVPKPVQIVPVHAALPWSERVATPA--EFDSIARSER--RRPFDLSRGPALRVVVLSV 127
              D     Q+V + AA   S+   TP   E D  AR        FD++    +RV    V
Sbjct: 6101 PVDGEDAHQVV-LPAADVVSDLTPTPVADEQDLFARMRELGATGFDVTETVPVRVACFEV 6159

Query: 128  PGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAKQDR 187
               T   ++   HHI  DG SLA  FT+++                    Y  +   Q  
Sbjct: 6160 -NPTDHILMMVVHHISADGASLAPLFTDVMTAYAARAAGSAPGWEPLPVQYADYALWQRE 6218

Query: 188  SAA------------LAGWMDYLRGVSEPLMVAYEATAG--QSKPGKTELLLPAADTAR- 232
            S              L  W   L G+ E L +  +      QS  G +      A T R 
Sbjct: 6219 SLGDESDPESLVARQLGYWQQALGGLPEVLELPTDRPRPPVQSLRGASARFSIDAQTHRA 6278

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L   A     TL   V  A AV+L RL+ + DV  GT V+GR +Q   ++ +VG+F+N +
Sbjct: 6279 LLAIAQETNTTLFMVVHAALAVLLERLSSQTDVAVGTPVAGRGEQ--ELDRLVGMFVNTL 6336

Query: 293  PVVHYVSGTEA---VVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSLFVFE 346
             +   V   +    ++AQ       + +  DV +  L E+    R     PLF     F+
Sbjct: 6337 VLRASVRPDDTFADLLAQVRATDLNAFSHSDVPFERLVEVLDVPRSTAHQPLFQVALSFD 6396

Query: 347  NAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVS---HLRXXXXXXXXXXXXXXXPYL 403
            N   ++++R        +F  +E+ +L   PL V      L                 + 
Sbjct: 6397 N---NESVR-------MEFPGLEISALDA-PLEVAKFDLQLSVGERYADGAAAGIAATFN 6445

Query: 404  PAAEI---------GERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDT 454
             + +I          +R + +L  +    D    D++I  AAE  A  +   R   + + 
Sbjct: 6446 YSTDIFDEQTVVGFADRFVRILGAVSSDRDVVLGDIEILDAAEKAA--IAPVRGPKSVEP 6503

Query: 455  TVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPR 514
            +      R               G + TY EL  ++ RLA  L + GVGPE  VAL + R
Sbjct: 6504 STLPELLRSGVEISPDSVAVSFQGRKLTYRELDEQSNRLARVLIDRGVGPENYVALAITR 6563

Query: 515  SERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEA-DYSQLVGTAVPTL 573
            S  S             YLPVD  LP  R+  ++  +   L +T A  ++ L GTA   +
Sbjct: 6564 SVESILGIWSIAKAGGAYLPVDPKLPFERIGEMLSDSGAVLGLTVARHHADLPGTA-EWI 6622

Query: 574  ALDDPAAVESISRRSAAAPTVD--RRP---EQSAYVIFTSGSTGEPKGVVGTNAAVLSYF 628
             LD+P A E I+ RSA A  V   RR    +  AY+I+TSGSTG+PKGVV T+  + +  
Sbjct: 6623 VLDEPEAAEQIAARSAVAVAVADLRRALTVDHPAYLIYTSGSTGKPKGVVVTHRGLANLT 6682

Query: 629  ADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLV 688
             +  E                 H  S SFD S   M+         +    ++   D L 
Sbjct: 6683 REVREHYVVSPDSRFL------HVASPSFDTSVGEMLAAFSAGATLVISPADVYGGDELA 6736

Query: 689  EGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNC 748
            + I   Q++ +  TP+  + +   GL   +++ + +GG+     L    R      + N 
Sbjct: 6737 DLIRREQVNNVVMTPTALMTVDPDGL--DSVTSVVVGGDTCTPEL--VARWAPGREMRNA 6792

Query: 749  YGPTEMTVEXXXXXXKDY-RKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLAR 807
            YGPTE TV            + TIG+   G    + DS LR VP+GV GELY+ G  + R
Sbjct: 6793 YGPTETTVIVTITEPMVAGERVTIGSPLRGVESLILDSRLRPVPEGVPGELYICGPSVTR 6852

Query: 808  GYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVG 866
            GY  RP +TA RFVA+P   PG RMYRTGD+VR        YVGR+D QVK+RG+RVE+G
Sbjct: 6853 GYHNRPSVTAERFVANPFGEPGARMYRTGDVVRWADGHRVEYVGRSDFQVKVRGFRVELG 6912

Query: 867  EIEAALRGQPGVHDAAVSVLRQQDR--TSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMV 924
            EI+AAL  QP + + AV+V R+     T+LV +V+  D    +   L++ + E LP YMV
Sbjct: 6913 EIDAALTAQPDI-EFAVTVGRENPAGLTTLVSYVLPADGATVEPESLKSVVGETLPPYMV 6971

Query: 925  PARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA 984
            P+ ++ L  +P+   GKLD     RL E    S +G    + +T  E  +  +F + L  
Sbjct: 6972 PSVVIVLDEIPLTGIGKLD---RARLPEPEFVS-AGAEFRAPATPAEETVAGIFADVLGL 7027

Query: 985  VP-HIDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAI---DAAVD 1039
                +DD  F  G +S+ A  +V +A +  GLR+  R +  A T+  L A I   D  V 
Sbjct: 7028 EQVSVDDSFFDLGGNSLSATRVVSRAGQVFGLRIGVRELFEAPTVAGLAARIATPDENVR 7087

Query: 1040 SQDAPADADYGAVRPLPMVS---WLYEY--GNYRRFTHTVLLRLPSGIDRSSIELMLQLL 1094
             + A A  +  A  PL +     W       +   +   + +RL   +D  +++  +  +
Sbjct: 7088 PRPALAPRERSAFVPLSLAQSRMWFINRFDPDSPAYNIPLAVRLTGALDVDALQSAVFDV 7147

Query: 1095 LDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTD 1154
            L  H++LR+I  ++ +GP  V    A V  +     +T  E    +L   VA    V  D
Sbjct: 7148 LGRHESLRTIYPDSADGPHQVVLPTAQVPIDVAPVPVTEAE-LRKQLTEMVATGFDVTAD 7206

Query: 1155 QIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGT 1214
             I P     VR       ++      +L L  HH++ D  S    + D+  A+ S  AG 
Sbjct: 7207 -IPP---MRVRLFEVGPQDY------VLALVVHHVSTDGESTAPFVRDVMVAYASRAAGR 7256

Query: 1215 PPKILP---EFTSYRRWCELMWHRASAPQ--VQDQRDYWAALVREPDPALGLRYPDPTRD 1269
             P   P   ++  Y  W   +      P   +  Q  +W   +      L L    P R 
Sbjct: 7257 EPGFAPLPVQYADYAIWQRELLGSEDDPDSLIAAQLGFWTKTLAGVPDLLELPVDRP-RP 7315

Query: 1270 TWSTLQLTRAAIPVDV-TERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLV 1328
               +L+ +R    VD    R L A+ R       +    A AV   R    +D A G  +
Sbjct: 7316 PVQSLRGSRIDFTVDAEVHRGLAALARRHNASVFMAVHAAFAVLLSRLSGTEDIAVGTPI 7375

Query: 1329 ALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSH 1388
            A    GR +  LD    + VG F N   +R+         E  +R    A++      SH
Sbjct: 7376 A----GRGERELD----DVVGMFVNTLALRVQVDGRQTFDEILDR----AREADLEAFSH 7423

Query: 1389 LEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLG-GVADQPWSLLTGPYLDA 1447
             + +P +               LV+ ++P    ++     +G    +   + L  P L  
Sbjct: 7424 AD-VPFE--------------RLVEVLNPARSMAHHPIFQVGYSFQNTTKAELELPDLTV 7468

Query: 1448 LPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAA 1506
             P+D E D       +L + +G + EG Q+ G + ++  +F+ + +     +++R +AA
Sbjct: 7469 TPLDVEGDTA---QFDLHLILGDSPEGEQMSGVFTFATDLFDAATVQRFADMFRRVLAA 7524



 Score =  347 bits (890), Expect = 8e-93
 Identities = 397/1437 (27%), Positives = 606/1437 (42%), Gaps = 141/1437 (9%)

Query: 14   LSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDR 73
            LS  Q  ++ +++   D    Y++   V + G +D++ L+ +   +L RH +LR  + D 
Sbjct: 7103 LSLAQSRMWFINRFDPDS-PAYNIPLAVRLTGALDVDALQSAVFDVLGRHESLRTIYPDS 7161

Query: 74   -DVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRG-PALRVVVLSVPGET 131
             D P  V +      +  +    T AE            FD++   P +RV +  V G  
Sbjct: 7162 ADGPHQVVLPTAQVPIDVAPVPVTEAELRKQLTEMVATGFDVTADIPPMRVRLFEV-GPQ 7220

Query: 132  KRRMIFTAHHILVDGWSLAVFFTELL---AVXXXXXXXXXXXXXXXXXXYIVW----LAK 184
               +    HH+  DG S A F  +++   A                   Y +W    L  
Sbjct: 7221 DYVLALVVHHVSTDGESTAPFVRDVMVAYASRAAGREPGFAPLPVQYADYAIWQRELLGS 7280

Query: 185  QDR-----SAALAGWMDYLRGVSEPLMVAYEATAG--QSKPG-KTELLLPAADTARLRQW 236
            +D      +A L  W   L GV + L +  +      QS  G + +  + A     L   
Sbjct: 7281 EDDPDSLIAAQLGFWTKTLAGVPDLLELPVDRPRPPVQSLRGSRIDFTVDAEVHRGLAAL 7340

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A RH  ++  AV  A+AV+LSRL+   D+  GT ++GR ++   ++ +VG+F+N + +  
Sbjct: 7341 ARRHNASVFMAVHAAFAVLLSRLSGTEDIAVGTPIAGRGER--ELDDVVGMFVNTLALRV 7398

Query: 297  YVSGTEA---VVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSLFVFENAPI 350
             V G +    ++ +  +   ++ +  DV +  L E+    R     P+F   + F+N   
Sbjct: 7399 QVDGRQTFDEILDRAREADLEAFSHADVPFERLVEVLNPARSMAHHPIFQVGYSFQNTTK 7458

Query: 351  DDAIRPATTPDGAQFLPVEMESLT-HYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIG 409
             +   P  T       P+++E  T  + L ++  L                  L  A   
Sbjct: 7459 AELELPDLT-----VTPLDVEGDTAQFDLHLI--LGDSPEGEQMSGVFTFATDLFDAATV 7511

Query: 410  ERMLTVLRQLPDIGDGTP----DDLDIRTAAELKAHGLLAA----RSAPTFDTTVWEMFE 461
            +R   + R++      +P     DL +  + E     L+ +     + P  +TT+ +MF 
Sbjct: 7512 QRFADMFRRVLAAAVDSPRTAVGDLPLAGSDE---RALVVSGWNDTAQPLPETTLADMFA 7568

Query: 462  RQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXX 521
                            G   TYAE  AR  +LA  L   GVGPETVV L +PRS      
Sbjct: 7569 AAAAENPDVTALVSD-GESLTYAEFSARVNQLARHLVGRGVGPETVVGLAIPRSVELLVG 7627

Query: 522  XXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALD----- 576
                      YLP+D   P+ R   ++  A P   +T  D +  +   V  L LD     
Sbjct: 7628 MYAITAAGGAYLPIDPDHPAERTAYVLESAQPVCVLTTRDVAGGLPGDVDYLFLDELDLG 7687

Query: 577  --DPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAER 634
              DPA +    R    AP    RP+ +AYVI+TSGSTG PKGV   + A+ +        
Sbjct: 7688 GIDPAPLADSER---IAPL---RPQNAAYVIYTSGSTGRPKGVAIAHGAIANQLR----- 7736

Query: 635  VYXXXXXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAI 693
             +                 + +FD S W+    L  G  + +   +  RD   L   +A 
Sbjct: 7737 -WKQAEYPLTADDSVLLKTAATFDLSVWEFWWALTAGARLVVATPDGHRDPSYLAGLVAE 7795

Query: 694  GQIDMIDTTPSM---FVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYG 750
             Q+  +   PS+   FV ++    L     VL +G EA+      + R +    ++N YG
Sbjct: 7796 QQVSTVHFVPSLLSAFVAVAEPAQLVSLRRVLCIG-EALPADTVLRFRDICDAEIFNLYG 7854

Query: 751  PTEMTVEXXXXXXKDYRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARG 808
            PTE  V       +D R  +  IG     T  YV DS L  VP GV GELYL+G QLARG
Sbjct: 7855 PTEAAVSVTHYRCRDERDGSVPIGRPEWNTQTYVLDSRLHPVPAGVTGELYLAGEQLARG 7914

Query: 809  YVGRPGMTAARFVADPLR-PGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGE 867
            Y GR  +TA RFVA P    G RMYRTGDLVR    G   YVGR+D QVK+RG+R+E+GE
Sbjct: 7915 YFGRHDLTAERFVASPFGVAGARMYRTGDLVRWNRDGDLDYVGRSDFQVKVRGFRIELGE 7974

Query: 868  IEAALRGQPGVHDAAVSVLRQQDRTS---LVGFVVWQDNMHEDLIKLRAGLTERLPSYMV 924
            IE AL   P V  A V V    DR +   LVG+VV +     D   + A   + +P YMV
Sbjct: 7975 IERALVAHPAVAQAVVVV--HHDRHTGDRLVGYVVPEPGDSVDDADVLAFAGKSVPGYMV 8032

Query: 925  PARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTA---VSASTDTERVLCELFEEQ 981
            P+ ++ L  LP+N NGKLD  AL            GG A    +  T  E ++  +F + 
Sbjct: 8033 PSALIALDELPLNINGKLDRKALPE-------PEFGGAADHYRAPRTPVEEIVAGVFADV 8085

Query: 982  L-NAVPHIDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAIDAAVD 1039
            L +     D   F  G +S+VA  +V +        +  R +  A T+  L A  + + D
Sbjct: 8086 LGHERVSADTSFFDLGGNSLVATRVVARINAALDTSIGVRELFEAPTVIALSARAEQS-D 8144

Query: 1040 SQDAPADADYGAVRPL-----PMVSWLYEYGNY----RRFTHTVLLRLPSGIDRSSIELM 1090
            S  A   A     RP      P  S ++    +      +   + +RL   +D +++   
Sbjct: 8145 SAGANRPALVPQPRPTRIPLSPAQSRMWFINQFDTASAAYNIPLAIRLTGRLDVAALGQA 8204

Query: 1091 LQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAAR 1150
            L  +++ H+TLR+   +T +GP  V     +VRA DV       E   DE A        
Sbjct: 8205 LGDVVERHETLRTTYPDTGDGPGQVVLPARSVRALDV-------EDVADESALR-ERVIS 8256

Query: 1151 VVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSL 1210
            +VT   D +    VRA   R    +    ++L++  HH++ D  S   +  D+  A+ + 
Sbjct: 8257 LVTAGFDVAQAVPVRARLLRIDAEQ----HVLVIVVHHISSDGASTAPLARDVVIAYSAR 8312

Query: 1211 QAGTPPKILP---EFTSYRRWCELMWHRASAPQ--VQDQRDYWAALVREPDPALGLRYPD 1265
             AG+ P   P   ++  +  W   +    +AP      Q DYW   +      L    P 
Sbjct: 8313 AAGSEPAWAPLDVQYADFSLWQHELLGDENAPDSLATKQIDYWRTTLSGLPDVL----PL 8368

Query: 1266 PTRDTWSTLQLTRAA-----IPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQ 1320
            PT       Q  R A     I  ++ +R LGA+ R+      ++A  A++V   R     
Sbjct: 8369 PTDRPRPPAQSMRGANFDFEIDAELRDR-LGALAREHNASLFMVAHAALSVLLARLSATD 8427

Query: 1321 DPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVA 1377
            D A G  +     GR +A LD    + VG F N   +R     A VD+E    D +A
Sbjct: 8428 DIAVGTAI----EGRGEAALD----DLVGMFVNTLVLR-----AHVDVESTFADLLA 8471



 Score =  295 bits (754), Expect = 4e-77
 Identities = 383/1417 (27%), Positives = 581/1417 (41%), Gaps = 127/1417 (8%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            L LS  Q+ ++ L++  +     Y++   V + G +D+  L  +   ++ RH  LR  F 
Sbjct: 3799 LPLSLAQQRMWFLNRF-DPSSPAYNVPLTVRLRGELDVAALAAALSDVVARHEVLRTVFP 3857

Query: 72   DRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSER--RRPFDLSRGPALRVVVLSVPG 129
            D +      I+P  A +  +       E D   R        FD++    +R  +  + G
Sbjct: 3858 DSESGAHQVILPA-AGIDLALDPVDVREEDLRDRMFEFGATGFDVTDTIPVRTRLFRL-G 3915

Query: 130  ETKRRMIFTAHHILVDGWSLAVFFTELL---AVXXXXXXXXXXXXXXXXXXYIVW----L 182
             T   ++   HHI  DG S      +++   A                   Y +W    L
Sbjct: 3916 ATDHVLVLVMHHIASDGASTLPLARDVMTAYAAHREGTEPAWPVLPVQYADYALWQRDVL 3975

Query: 183  AKQDRSAALAG-----WMDYLRGVSEPLMVAYEATAG--QSKPGKTELLLPAADT-ARLR 234
              +    +LA      W   L GV + L +  +      +S  G +      AD   RL 
Sbjct: 3976 GSEGDPDSLAAAQIDFWSKTLAGVPDVLALPTDRPRPTVRSMAGASVGFSVDADVHRRLG 4035

Query: 235  QWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPV 294
            + A  H ++L   +  + +V+L+RL+   D+  G  V+GR D+   +E +VG+F+N + +
Sbjct: 4036 EVARAHNVSLFMVLHASLSVLLARLSSSTDIAIGAAVAGRGDE--ALENLVGMFVNTLVL 4093

Query: 295  VHYVSGTEAVVAQCTQVQRQSSAM---RDVSYLSLSEI---QREHGRGPLFDSLFVFENA 348
               V    +      QV+ Q  A    +DV +  L +     R     PLF  +   +  
Sbjct: 4094 RTEVEPGTSFADLLEQVRTQDLAAFSNQDVPFEQLVDALKPTRSTAYSPLFQVVLTHQVN 4153

Query: 349  PIDDAIRPATTPDGAQFLPVEME-SLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAE 407
             I     PA    G +  P  ++   + + LTV   LR                   A E
Sbjct: 4154 GI-----PALEFAGLEATPGAVDVEFSKFDLTV--DLRELWSDEGAPTGITGVLGY-ATE 4205

Query: 408  I---------GERMLTVLRQLPDIGD----GTPDDLDIRTAAELK-AHGLLAARSAPTFD 453
            I          +R + +L  + D G     G    LD +  AEL    G+     APT  
Sbjct: 4206 IFDAETVQGFADRFVRILAAVADGGTDVAVGDIPILDAQETAELTPVRGIEGV--APT-- 4261

Query: 454  TTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLP 513
             T+ E+    V             G   TY EL  R+ RLA  L E GVG ET V L + 
Sbjct: 4262 -TLVELLAAAVAADPDGDAIVAG-GDSITYRELDERSNRLARILIERGVGAETFVGLGIT 4319

Query: 514  RSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTL 573
            RS  S             Y+P+D   P  R+  +V  +  AL ++ +     +   V  L
Sbjct: 4320 RSIPSIVGIWAVAKSGGAYVPIDPGYPDERIAHMVTDSGVALGLSVSSEVGRLPRDVDWL 4379

Query: 574  ALDDPAAVESISRRSAAAPTVDRR-----PEQSAYVIFTSGSTGEPKGVVGTNAAVLSYF 628
             LD    V++ +R S A  T   R     P  SAYVI+TSG+TG+PKGVV T+  + ++ 
Sbjct: 4380 VLDSEEFVDASARYSTAPVTEAERRTAVEPANSAYVIYTSGTTGQPKGVVVTHRGLANFA 4439

Query: 629  ADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLV 688
            A+  ER                H  S SFDAS   ++  +      +    ++       
Sbjct: 4440 AEQRERY------RVTTDSRTLHFASPSFDASVLELLLAVGAGATMVIAPTDVYGGPEFA 4493

Query: 689  EGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNC 748
            + +   ++     TPS    +  +GL D    V   GGEA+   L    R     +++N 
Sbjct: 4494 KFLREQRVTHGFVTPSALASVDPSGLDDFQFVVA--GGEAVPAEL--AARWAPGRSLFNG 4549

Query: 749  YGPTEMTVEXXXXXXKDYRKP-TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLAR 807
            YGPTE T+            P TIG    GT   V D  LR VP G+ G+LYLSG  LAR
Sbjct: 4550 YGPTETTIMTNISDPMAADGPVTIGGPIRGTSALVLDDRLRPVPVGIAGDLYLSGLGLAR 4609

Query: 808  GYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYA----YVGRADTQVKIRGYR 862
            GY  R  +TA RFVA+P   PG RMYRTGD+VR       A    YVGR+D QVK+RG+R
Sbjct: 4610 GYHRRTPLTAGRFVANPYGAPGDRMYRTGDVVRWKKDADGALTVDYVGRSDQQVKVRGFR 4669

Query: 863  VEVGEIEAALRGQPGVHDAAVSVLRQQDRTS-LVGFVVWQDNMHEDLIKLRAGLTERLPS 921
            +E+GEI+A L   P V  A  SVL      S LV +V+       ++  +   + E +P+
Sbjct: 4670 IELGEIDAVLAKHPAVDFATTSVLPGPSGDSVLVSYVLPAPGAEVNVAGVLDFVGEFVPT 4729

Query: 922  YMVPARIVTLPRLPVNANGKLDGHAL---DRLAEDALTSVSGGTAVSASTDTERVLCELF 978
            YMVP+ IVTL  +P+   GKLD  AL   + LAED     +G       T  E+ +  +F
Sbjct: 4730 YMVPSTIVTLDAIPLTPVGKLDRRALPEPEFLAEDREFRAAG-------TALEQRVAAVF 4782

Query: 979  EEQLNA-VPHIDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAIDA 1036
             E L       DD  F  G +S+ A  ++ +     G+    R +  A T+ QL   ++A
Sbjct: 4783 AEVLGVDQVGADDSFFTLGGNSLAATRVMARINEAVGIDAPVREIFEAPTVAQLARRLEA 4842

Query: 1037 -AVD-SQDAPADADYGAVR-PLPMVSWLYEYGN-----YRRFTHTVLLRLPSGIDRSSIE 1088
              VD     P  A     R PL +      Y N        +   + LRL   +D  ++ 
Sbjct: 4843 LGVDGGARPPVTAGPRPDRLPLSLAQQRMWYANRFDPESAEYNIPLALRLTGALDVDALT 4902

Query: 1089 LMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHA 1148
              +  ++  H++LR++  ++ +GP  V    +  ++   + R+      + EL   V   
Sbjct: 4903 TAIADVVTRHESLRTVYPDSVDGPYQVVLSASDTKSALDVVRV----ADEQELRERVVTL 4958

Query: 1149 ARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWR 1208
            A   +   D +A   VRA  F   EH     ++L++  HH++ D  S   +  DL  A+ 
Sbjct: 4959 A---SAGFDVTADVPVRAALFALGEH----DHVLVVVVHHISADGSSMAPLARDLFGAYG 5011

Query: 1209 SLQAGTPPKILP---EFTSYRRWCELMWHRASAPQ--VQDQRDYWAALVREPDPALGLRY 1263
            +   G  P   P   ++  +  W   +      P+     Q  YW   + +    L L  
Sbjct: 5012 ARAQGEEPGFSPLPVQYPDFALWQRNLLGSEDDPESLAGKQIAYWTHALGDAPEVLDLP- 5070

Query: 1264 PDPTRDTWSTLQ--LTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQD 1321
             D  R      Q  L    I  DV  R L  + +       ++   A+AV   R     D
Sbjct: 5071 ADRPRPAVRNPQGGLIEFEIGQDV-HRSLNELAQTHQASLFMVVHAALAVLLGRLSNTGD 5129

Query: 1322 PAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
             +    VA    GR D  LD    + VG F N   +R
Sbjct: 5130 ISVSTPVA----GRGDRALD----DLVGMFVNTLVLR 5158



 Score =  294 bits (753), Expect = 6e-77
 Identities = 301/990 (30%), Positives = 428/990 (43%), Gaps = 96/990 (9%)

Query: 419  LPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTF----DTTVWEMFERQVQXXXXXXXXX 474
            LP + DG+  +    T A + A  +  A SA       + TV ++F+ QV          
Sbjct: 5396 LPGLLDGSSGEGFADTFAGVLAGVIADATSATAVTEAGERTVVDLFDEQVARTPDAVALV 5455

Query: 475  XXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLP 534
                   TYAE   R   LA  L   GVGPE  VAL + RS  S             Y+P
Sbjct: 5456 SGDESL-TYAEFDKRVNTLARTLIGMGVGPEVRVALAIRRSIDSMVAMYAILKAGGAYVP 5514

Query: 535  VDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAA-----VESISRRSA 589
            +D   P+ R   ++  ASP   +T           V   ALD PA      ++ +S   A
Sbjct: 5515 LDPDHPAERTSYVLDSASPLCILT-----------VARDALDLPAGHTVVEIDRLSGDEA 5563

Query: 590  AAPTVDR--------------RPEQSAYVIFTSGSTGEPKGVVGTNAAVL---SYFADHA 632
            AAP  D               R    AYVI+TSGSTG PKGV  ++AAVL   S+  D  
Sbjct: 5564 AAPLGDEAAVPPGDEERRGTLRASNPAYVIYTSGSTGRPKGVAVSHAAVLNQISWIVDQY 5623

Query: 633  ERVYXXXXXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGI 691
            E                      +FD S W+    L+ G  + +   +   D + L   I
Sbjct: 5624 E---------LGAHDVVLQKTPATFDVSVWELFGTLVAGARLVIASPDGHGDPEYLAALI 5674

Query: 692  AIGQIDMIDTTPSMF-VQLSAAGLLDH-NLSVLALGGEAINTGLWDQLRGLSQMAVYNCY 749
            A   +      PSM  V +  AG  D  +L V+ + GEA      +  RGLS   ++N Y
Sbjct: 5675 AREGVTATSFVPSMLSVFVGEAGRDDLLSLRVVLVAGEAFPPATAEAFRGLSDAELHNLY 5734

Query: 750  GPTEMTVEXXXXXXKDYRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLAR 807
            GPTE TV           + T  IG A   T  +V DS LR VP GV GELYL+G QLAR
Sbjct: 5735 GPTEFTVHATAGQVDPGVRGTVPIGRAVRNTDLHVLDSRLRPVPVGVPGELYLAGTQLAR 5794

Query: 808  GYVGRPGMTAARFVADPLRP-GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVG 866
            GYVGR  +T+ RFVA+P    GQRMYRTGD+VRR + G   Y+GR+D QVK+RG R+E+G
Sbjct: 5795 GYVGRSDLTSDRFVANPFGGHGQRMYRTGDVVRRRADGNLEYIGRSDFQVKLRGLRIELG 5854

Query: 867  EIEAALRGQPGVHDAAVSVLRQQDR-TSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVP 925
            E+EAAL     +  AAV++ R +    +LV +VV +     D   ++    + LP+YMVP
Sbjct: 5855 EVEAALLTHESLAQAAVTIHRSESTGENLVAYVVPRSGARVDTKSVQDAAAQVLPAYMVP 5914

Query: 926  ARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA- 984
            ARIV L   P+ A+GKLD  AL    E A  +V     V+  T  E V+  +F + L A 
Sbjct: 5915 ARIVVLDSFPLGASGKLDRKALPE-PEFATVAVE---YVAPRTPMETVVASVFADVLGAD 5970

Query: 985  VPHIDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAID---AAVDS 1040
                 D  F  G +SI A  L  + R   G  +  R      T+ +L A ++      + 
Sbjct: 5971 RVGSADSFFDLGGNSISATRLTARLRAAVGAHLSVRECFENPTVAELAALLETTSGTAEQ 6030

Query: 1041 QDAPADADYGAVRPLPMVSWLYEYGNY-----RRFTHTVLLRLPSGIDRSSIELMLQLLL 1095
            + A A     A  PL +      + N        +   + +RL   ID +++      ++
Sbjct: 6031 RPALAARPRPARIPLSLAQQRMWFVNQFDPSSPAYNLPLAVRLTGSIDPAALNSAWADVV 6090

Query: 1096 DGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQ 1155
            + H++LR++     E    V      + A DV++ +T    +D++   A           
Sbjct: 6091 ERHESLRTVFPVDGEDAHQV-----VLPAADVVSDLTPTPVADEQDLFARMRELGATGFD 6145

Query: 1156 IDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTP 1215
            +  +    V       T+H      IL++  HH++ D  S   +  D+  A+ +  AG+ 
Sbjct: 6146 VTETVPVRVACFEVNPTDH------ILMMVVHHISADGASLAPLFTDVMTAYAARAAGSA 6199

Query: 1216 PKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALG-----LRYP-DPTRD 1269
            P   P    Y  +   +W R S     D     A  +     ALG     L  P D  R 
Sbjct: 6200 PGWEPLPVQYADYA--LWQRESLGDESDPESLVARQLGYWQQALGGLPEVLELPTDRPRP 6257

Query: 1270 TWSTLQLTRAAIPVDV-TERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLV 1328
               +L+   A   +D  T R L A+ ++      ++   A+AV   R     D A G  V
Sbjct: 6258 PVQSLRGASARFSIDAQTHRALLAIAQETNTTLFMVVHAALAVLLERLSSQTDVAVGTPV 6317

Query: 1329 ALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
            A    GR +  LD      VG F N   +R
Sbjct: 6318 A----GRGEQELD----RLVGMFVNTLVLR 6339



 Score =  262 bits (670), Expect = 2e-67
 Identities = 282/960 (29%), Positives = 409/960 (42%), Gaps = 112/960 (11%)

Query: 478  GVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDV 537
            GV  +  E++ RA +LA EL   GV P+ VVAL+ PRS                Y P D 
Sbjct: 3211 GVSTSRGEVNRRANQLARELVSRGVRPDDVVALLTPRSLEWVIGMIAAWKVGAAYSPFDQ 3270

Query: 538  TLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAV---ESISRRSAAAPTV 594
                 R+  +V  +     +    +S L G      ALDDP  +   E++        T 
Sbjct: 3271 KWAIERITGLVEDSGTRAVVATRSWSGLTGAPTGNAALDDPIVLDDPETVRHLETLDGTD 3330

Query: 595  --------DRRPEQSAYVIFTSGSTGEPKG----VVGTNAAVLSYFADHAERVYXXXXXX 642
                    +   ++  +VI TSGSTG PK     ++G +    SY  D   +        
Sbjct: 3331 FPHDPWSDEHAGKRLGHVISTSGSTGRPKPTMVPMLGLSNNYQSYQGDLRVK-------- 3382

Query: 643  XXXXXXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDT 701
                     A S  FD + + + VGL  G  +HL  A++  D   ++  I  G + + + 
Sbjct: 3383 --DGTGLLIANSPLFDQTQKNIWVGLAYGGVLHL--ADDGFDPGPILRMIGTGDVQITNL 3438

Query: 702  TPSMF---VQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV-- 756
             PS F    +L   G+L  NL V+ LGGE +       L G +   V N YGPTE +V  
Sbjct: 3439 APSAFEVLTELDTEGVLP-NLKVILLGGEMLRPAACTALIG-TDSRVLNNYGPTEASVTC 3496

Query: 757  ---EXXXXXXKDYRKPT-IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGR 812
               E         + P   GTA  G   +V D  +R VP GV G+LY+ G  LARGY   
Sbjct: 3497 SSYELDLSTADAEKWPVPFGTAFRGVRYHVLDGRMRPVPPGVTGDLYIGGQVLARGYGNM 3556

Query: 813  PGMTAARFVADPLR-PGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAA 871
             G TA+RFVA+P   PG RMYRTGD VR L HGG  +VGR+D QVKIRG R+E+GEIE+A
Sbjct: 3557 FGTTASRFVANPFEGPGARMYRTGDRVRELDHGGLVFVGRSDFQVKIRGLRIELGEIESA 3616

Query: 872  LRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTL 931
            L     V  + V V   +    LV +V        D       L + LPS+M+P  ++ L
Sbjct: 3617 LTANSAVQKSVVVVHDSEQGPRLVAYVTATAGAELDADATVEALLDVLPSHMIPDTVMVL 3676

Query: 932  PRLPVNANGKLDGHALDRLAEDALTSVSGGTA--VSASTDTERVLCELFEEQLNAVPH-- 987
              +P+NAN K+D  A   L E   T+   GT   V+  T  E V+  +F + + +VP   
Sbjct: 3677 DEMPLNANLKVDRKA---LPEPVFTT---GTVEFVAPRTPLEEVVAGIFGDVI-SVPRVS 3729

Query: 988  IDDDLFLFGMDSIVAISLVHK-ARRQGLRVDPRMVLTATTIRQLGAAI-DAAVDSQDAPA 1045
            +D+  F  G +S+ A  +  +     G  V  R +  A T+  L   + D A +    PA
Sbjct: 3730 VDESFFDLGGNSLSATRVAARVTSATGTEVGIRDLFEAPTVATLAKLVEDRAHNGSRRPA 3789

Query: 1046 DADYGAVRPLPMVSWLYEYGNYRRFTHT-------VLLRLPSGIDRSSIELMLQLLLDGH 1098
                   R LP+           RF  +       + +RL   +D +++   L  ++  H
Sbjct: 3790 LVAGRRPRALPLSLAQQRMWFLNRFDPSSPAYNVPLTVRLRGELDVAALAAALSDVVARH 3849

Query: 1099 DTLRSILTETPEGPRLV---------TREPAAVRAEDVLTRITLPEGSDDELASAVAHAA 1149
            + LR++  ++  G   V           +P  VR ED+  R+                  
Sbjct: 3850 EVLRTVFPDSESGAHQVILPAAGIDLALDPVDVREEDLRDRM-----------FEFGATG 3898

Query: 1150 RVVTDQIDPSAGAMVRAIWFR--GTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAW 1207
              VTD I       VR   FR   T+H      +L+L  HH+A D  S   +  D+  A+
Sbjct: 3899 FDVTDTIP------VRTRLFRLGATDH------VLVLVMHHIASDGASTLPLARDVMTAY 3946

Query: 1208 RSLQAGTPP--KILP-EFTSYRRWCELMWHRASAPQ--VQDQRDYWAALVREPDPALGLR 1262
             + + GT P   +LP ++  Y  W   +      P      Q D+W+  +      L L 
Sbjct: 3947 AAHREGTEPAWPVLPVQYADYALWQRDVLGSEGDPDSLAAAQIDFWSKTLAGVPDVLALP 4006

Query: 1263 YPDPTRDTWSTLQLTRAAIPVDV-TERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQD 1321
              D  R T  ++        VD    R LG V R   V   ++   +++V   R   + D
Sbjct: 4007 -TDRPRPTVRSMAGASVGFSVDADVHRRLGEVARAHNVSLFMVLHASLSVLLARLSSSTD 4065

Query: 1322 PAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR--LGAGAAAVD-IEQAERDPVAA 1378
             A G  VA    GR D  L+    N VG F N   +R  +  G +  D +EQ     +AA
Sbjct: 4066 IAIGAAVA----GRGDEALE----NLVGMFVNTLVLRTEVEPGTSFADLLEQVRTQDLAA 4117



 Score = 83.2 bits (204), Expect = 3e-13
 Identities = 127/541 (23%), Positives = 211/541 (39%), Gaps = 47/541 (8%)

Query: 4    AAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRH 63
            A P+ E V  LS  Q+ ++ +++  +     Y++   V + G +D++ +  +   +L RH
Sbjct: 2599 ARPRPERV-PLSMAQQSMWLMNRF-DTASSAYNIPLAVRLSGALDIDAMSSAVSDVLARH 2656

Query: 64   PNLRAAFWDRDVPKPVQIVPVHAALPWS-ERVATP-AEFDSIARSERRRPFDLSRGPALR 121
             +LR  F D       Q+V V A +P+    V  P AE  +         FD++  P LR
Sbjct: 2657 ESLRTVFPDSADGPYQQVVDV-AQVPFDLTPVRVPEAELHTALTEFAAEGFDVTVAPPLR 2715

Query: 122  VVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY--- 178
            + + +   +T+  ++   HHI  DG S+A    +++                    Y   
Sbjct: 2716 IRLFAT-SDTEFLLVLVVHHICADGASMAPLARDVMVAYSARTAGAAPLWQPLPVQYPDF 2774

Query: 179  IVW----LAKQDRSAALAG-----WMDYLRGVSE--PLMVAYEATAGQSKPGKTELLLPA 227
             +W    L     + +LAG     W D L G  E   L + +   A QS  G +   +  
Sbjct: 2775 ALWQRDVLGDPADTQSLAGKQIAHWADTLAGAPELIDLPLDHIRPARQSMRGDS---IDF 2831

Query: 228  ADTARLR---QWAGR-HGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVET 283
            A T  LR   +  G+  G +L      A   +LSRL+   D+  GT ++ R DQ   ++ 
Sbjct: 2832 AITPELRHGLEAVGKDRGASLFMVTHAALTTLLSRLSSSDDITVGTPLAARGDQ--ALDD 2889

Query: 284  MVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAM---RDVSYLSLSE---IQREHGRGP 337
            +VG+F+N + +   V   ++      +V+    A     DV +  + E   I+R     P
Sbjct: 2890 LVGMFVNTLVLRTQVRPGDSFAGLVDRVREGDLAAFGNSDVPFEKIVEALRIRRSAAYSP 2949

Query: 338  LFDSLFVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVV------SHLRXXXXXX 391
            LF  +  F+N  +D    P  T         +M     Y LT+          R      
Sbjct: 2950 LFQVMLSFQNNRMDALELPGLTVRVID----DMAQGAKYDLTLTITEKADESGRPAGLGG 3005

Query: 392  XXXXXXXXXPYLPAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPT 451
                         A  I ER + +L  +         D+DI T  E +   L  AR A T
Sbjct: 3006 RFTFATDLFERGTAERIAERFVRILEAVVTDPGVAVGDIDILT--EHERAKLSQARPART 3063

Query: 452  FDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALV 511
                                      G++ TY E   R   ++  L+E G+GP+ +V++V
Sbjct: 3064 MTVRELPQLLAAAVEVAPDAVAVAHDGMQVTYREFDERLRMMSAPLSERGMGPDAIVSVV 3123

Query: 512  L 512
            L
Sbjct: 3124 L 3124



 Score = 65.1 bits (157), Expect = 7e-08
 Identities = 124/556 (22%), Positives = 201/556 (36%), Gaps = 76/556 (13%)

Query: 10   DVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAA 69
            D L LS  Q+ ++  ++   +  + Y++   + + G +D++ L  +   ++ RH +LR  
Sbjct: 4860 DRLPLSLAQQRMWYANRFDPESAE-YNIPLALRLTGALDVDALTTAIADVVTRHESLRTV 4918

Query: 70   FWDRDVPKPVQIV----PVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVL 125
            + D  V  P Q+V       +AL    RVA   E      +     FD++    +R  + 
Sbjct: 4919 YPD-SVDGPYQVVLSASDTKSALD-VVRVADEQELRERVVTLASAGFDVTADVPVRAALF 4976

Query: 126  SVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY---IVW- 181
            ++ GE    ++   HHI  DG S+A    +L                     Y    +W 
Sbjct: 4977 AL-GEHDHVLVVVVHHISADGSSMAPLARDLFGAYGARAQGEEPGFSPLPVQYPDFALWQ 5035

Query: 182  ---LAKQDRSAALAG-----WMDYLRGVSEPLMVAYEATAGQSKP-------GKTELLLP 226
               L  +D   +LAG     W   L    E L    +  A + +P       G  E  + 
Sbjct: 5036 RNLLGSEDDPESLAGKQIAYWTHALGDAPEVL----DLPADRPRPAVRNPQGGLIEFEIG 5091

Query: 227  AADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVG 286
                  L + A  H  +L   V  A AV+L RL++  D+   T V+GR D+   ++ +VG
Sbjct: 5092 QDVHRSLNELAQTHQASLFMVVHAALAVLLGRLSNTGDISVSTPVAGRGDR--ALDDLVG 5149

Query: 287  LFINAVPV---VHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFD 340
            +F+N + +   V   +    ++ Q  +V   +    DV +  + E+    R     PL  
Sbjct: 5150 MFVNTLVLRTEVDQNARFSTLLTQAREVDLNAFGNADVPFEQIVEVLRPSRTAAYAPLAQ 5209

Query: 341  SLFVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXX 400
             +  F+N       RP     G     +E    T      V+                  
Sbjct: 5210 VMLSFQNLE-----RPKLELAGLTVEVLESGLTTSKTDLGVAVEERFDDDSVANGMRGWF 5264

Query: 401  PY-------LPAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAE-------------LKA 440
             Y              +R + VL  +    D    D+DI T  E             L A
Sbjct: 5265 SYATDLFDEATVRGFADRFVRVLEAITADADAVVGDIDILTEDEKAGLAVPDEGGQSLLA 5324

Query: 441  HG----LLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGE 496
            H     L A +S P       E+ +                G   TYA+L  ++  LA  
Sbjct: 5325 HSISEELAATKSLP-------ELLDGAAS-INPDGIALSHNGTDVTYAQLRDKSAELART 5376

Query: 497  LAEHGVGPETVVALVL 512
            LA  GVGPE  V + L
Sbjct: 5377 LAGVGVGPEAAVTVAL 5392



 Score = 62.4 bits (150), Expect = 5e-07
 Identities = 83/373 (22%), Positives = 148/373 (39%), Gaps = 26/373 (6%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            + LSP Q  ++ ++Q  +     Y++   + + G +D+  L ++   +++RH  LR  + 
Sbjct: 8162 IPLSPAQSRMWFINQF-DTASAAYNIPLAIRLTGRLDVAALGQALGDVVERHETLRTTYP 8220

Query: 72   DRDVPKPVQIVPVHAALPWS-ERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSVPGE 130
            D        ++P  +      E VA  +       S     FD+++   +R  +L +  E
Sbjct: 8221 DTGDGPGQVVLPARSVRALDVEDVADESALRERVISLVTAGFDVAQAVPVRARLLRIDAE 8280

Query: 131  TKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYI---VW----LA 183
             +  ++   HHI  DG S A    +++                    Y    +W    L 
Sbjct: 8281 -QHVLVIVVHHISSDGASTAPLARDVVIAYSARAAGSEPAWAPLDVQYADFSLWQHELLG 8339

Query: 184  KQDRSAALAG-----WMDYLRGVSE--PLMVAYEATAGQSKPGKT-ELLLPAADTARLRQ 235
             ++   +LA      W   L G+ +  PL         QS  G   +  + A    RL  
Sbjct: 8340 DENAPDSLATKQIDYWRTTLSGLPDVLPLPTDRPRPPAQSMRGANFDFEIDAELRDRLGA 8399

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
             A  H  +L      A +V+L+RL+   D+  GT + GR +    ++ +VG+F+N + + 
Sbjct: 8400 LAREHNASLFMVAHAALSVLLARLSATDDIAVGTAIEGRGE--AALDDLVGMFVNTLVLR 8457

Query: 296  HYV---SGTEAVVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSLFVFENAP 349
             +V   S    ++AQ  Q    +    DV +  L EI   +R     PLF     F+N  
Sbjct: 8458 AHVDVESTFADLLAQVRQHDLGAFTHTDVPFERLVEILQPERSTAFSPLFQVALAFQNIE 8517

Query: 350  IDDAIRPATTPDG 362
                  P  T +G
Sbjct: 8518 QAHLELPGLTVEG 8530


>tr|A4FE38|A4FE38_SACEN Tax_Id=405948 SubName: Full=Putative
            non-ribosomal peptide synthetase;[Saccharopolyspora
            erythraea]
          Length = 5429

 Score =  696 bits (1795), Expect = 0.0
 Identities = 529/1524 (34%), Positives = 726/1524 (47%), Gaps = 96/1524 (6%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            ++EDVL ++PLQEGLF      E   D Y +Q VV++ G VD E +RR+ + + +RH  L
Sbjct: 1450 EVEDVLPVTPLQEGLFFHASFDESEADDYLVQQVVELRGQVDGESMRRAVRGLAERHAPL 1509

Query: 67   RAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLS 126
            RA F  R   + VQ+V     +PW E      + + +A  ER R FDLS  P +R  +  
Sbjct: 1510 RAGFRQRADGRVVQLVDRRVEVPWRE---VSGDVEQVAAEERSRRFDLSEAPLMRCAL-- 1564

Query: 127  VPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAKQD 186
            V G+ +  ++ T HHI+ DGWS  V   ELLA+                  Y+ WLA++D
Sbjct: 1565 VRGDGRHWLVLTLHHIVADGWSSPVMVRELLALHTPGEELPPVTAYRD---YLGWLAERD 1621

Query: 187  RSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRHGLTLNT 246
              AA   W D LRG+ EP ++A   T  +    +  + +P   TA L   A   G+TL+T
Sbjct: 1622 DEAARRAWRDALRGLDEPTLLA---TGDRGPLRQCTVDIPEQVTAGLAARARELGVTLST 1678

Query: 247  AVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEAVVA 306
             V  AW ++L RLT R DVVFGT VSGR  ++ GVE+MVGL  N VPV        ++  
Sbjct: 1679 VVQGAWGLLLGRLTGRCDVVFGTTVSGRAAEVAGVESMVGLLANTVPVRMRWQPGASIAD 1738

Query: 307  QCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDGAQFL 366
            + T++Q + S + D  +L L EIQR  G G LFD+L VFEN P ++ +  A+     +  
Sbjct: 1739 ELTRLQSEQSDLLDHQHLGLGEIQRLAGAGELFDTLLVFENYPSEERLTDAS--GTVEVA 1796

Query: 367  PVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQLPDIGDGT 426
              E     HYPLT+V                       A  I ERM  VL  +       
Sbjct: 1797 GSEFFGAGHYPLTLV----VMPGEKLELQFKHRLADAEARSIAERMARVLEAVAADPARP 1852

Query: 427  PDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAEL 486
               +++ +  E      L A +      T+ + FE QV                 +Y +L
Sbjct: 1853 AGRIELLSEREHDRLRELNATAREVSGRTLVDAFEAQV-AKTPDATAVVFGATEMSYVDL 1911

Query: 487  HARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVES 546
             A A RLA  L   G GPE VVA+ + RS                YLPVD+  P  R+  
Sbjct: 1912 DAAAERLAARLRARGAGPEQVVAVAVARSAELVVALLGVLKSGAAYLPVDLDYPEDRIAY 1971

Query: 547  IVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSAYVIF 606
            ++  +   L +T  D + L   A      D  + V   + +    P     P+  AY+I+
Sbjct: 1972 MLSDSRARLVVTTRDAAGLPEGAERLFVEDSDSDVSGSAPQDGPRPV----PDNPAYLIY 2027

Query: 607  TSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS-WQPMV 665
            TSGSTG PKGVV T+ A+++      +R                     SFD S W+   
Sbjct: 2028 TSGSTGRPKGVVVTHRAIVNRLEWMQDR------YRLGADDRVLQKTPSSFDVSVWEFFW 2081

Query: 666  GLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFV------QLSAAGLLDHNL 719
             L  G  + L   +  RD   L   +    I  +   PSM        +++A      +L
Sbjct: 2082 ALGVGAAVVLARPDGHRDPAYLAGLVRAQGITTMHFVPSMLAAFLGTDEVTADPGWASSL 2141

Query: 720  SVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVE---XXXXXXKDYRKPTIGTANA 776
              +   GEA+   L  Q   L+ + ++N YGPTE  V+          D   P IG    
Sbjct: 2142 RRVFSSGEALGGDLAAQWTELTGVRLHNLYGPTEAAVDVTWWPFDGAPDAVVP-IGWPVW 2200

Query: 777  GTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTG 835
             T  +V D  LR VPDGV GELYL+G QLARGY  R  +TA RFVADP   PG+RMYRTG
Sbjct: 2201 NTRLHVLDPCLRPVPDGVPGELYLAGVQLARGYHRRAELTAQRFVADPFGAPGERMYRTG 2260

Query: 836  DLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLV 895
            DLVRR   G   Y+GRAD QVKIRG R+E+GEIE+A+   PGV  AAV          LV
Sbjct: 2261 DLVRRRPDGAVEYLGRADRQVKIRGNRIELGEIESAMSRLPGVAHAAVVAREDGPSVRLV 2320

Query: 896  GFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDAL 955
            G+ V   +   D  +L A L   LP+ MVP   V L  LPV  +GKLD  AL   A    
Sbjct: 2321 GYFV--PSAPVDTAELEATLAAELPAAMVPTAFVELDALPVTPSGKLDRDALP--APSTR 2376

Query: 956  TSVSGGTAVSASTDTERVLCELFEEQLNAVPHIDDDLFLFGMDSIVAISLVHKARRQGLR 1015
             S +GG          R LCE+F + L     +DDD F  G DSI++I++  +AR+ GL 
Sbjct: 2377 RSAAGG----PGDQRRRRLCEIFADVLKQEVGVDDDFFALGGDSILSIAVSSRARKAGLD 2432

Query: 1016 VDPRMVLTATTIRQLGAAIDAAVDSQDAPADAD-YGAVRPLPMVSWLYEY-GNYRRFTHT 1073
            + PR V    T   L AA+     ++ A AD+D  G V  LP+V WL E  G+  RF  +
Sbjct: 2433 LSPRDVFEHRTPAAL-AALGGETPAEAAMADSDGVGDVALLPVVHWLRERGGSIDRFNLS 2491

Query: 1074 VLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGP-RLVTREPAAVRAEDVLTRIT 1132
            +LLR P+G     +   LQ +LD HD LR  LT        L TR   AV A +VL R+ 
Sbjct: 2492 MLLRTPAGAREQDLTAALQAVLDHHDALRLRLTRVAGVLWSLETRPAGAVSAREVLRRV- 2550

Query: 1133 LPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVD 1192
                   E A  V   A    D+++P AG ++RA+WF   E        L L  HHLAVD
Sbjct: 2551 -------ESAEPVQAEAESEVDRLEPEAGTVLRAVWFDAGEQPGH----LFLALHHLAVD 2599

Query: 1193 VVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALV 1252
             VSW I+  DL  AW +  AG  P + P  TS R +  ++  +A  P+   + +YW  ++
Sbjct: 2600 GVSWRILSEDLRTAWEAAVAGREPVLDPVGTSLRHFARVLTEQAQTPRRMGELEYWTEVL 2659

Query: 1253 REPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVL----GAVRRDQGVRELLLAATA 1308
            R   P   L        T  + + T   + V  TE +L     AVR D  V E+LLAA  
Sbjct: 2660 R---PGAELLPSANAGGTAGSARRTTTRLSVAETEPLLTDVPAAVRAD--VTEVLLAALR 2714

Query: 1309 MAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDI 1368
            +AV+ W     +D  A +LV +E HGR +     D + TVGWFT+  PVRL   A  +++
Sbjct: 2715 IAVSRWHERHGRDAGADLLVDVERHGREEITDGIDLSRTVGWFTSIQPVRLSGAAEPLEV 2774

Query: 1369 EQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAE--LVDAVDPQIQFSYLGR 1426
             ++ +D V              + P+ G+ +G+LR ++      L  A   Q+ F+YLGR
Sbjct: 2775 LRSVKDGV-------------RSAPDRGIGHGMLRGLNPQTAPILAGAASAQVLFNYLGR 2821

Query: 1427 LDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDA 1486
            L   G    P    TG    AL ++P+ DL   +AL +      T EG +L  +W W D 
Sbjct: 2822 LPASGGDWTP----TG----ALTVEPDDDLGTPYALQVDAVCDDTPEGPRLSLHWTWQDN 2873

Query: 1487 VFERSDIDHLTGLWQRGIAALAAG 1510
                 D+D L   W   + ALA G
Sbjct: 2874 ALSAEDVDELAAGWAEAVRALARG 2897



 Score =  565 bits (1456), Expect = e-158
 Identities = 451/1398 (32%), Positives = 647/1398 (46%), Gaps = 105/1398 (7%)

Query: 8    IEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLR 67
            +ED+  LSPLQEGLF      +  +D+Y+ Q  +D D  +DLE LR +   +L R+P+LR
Sbjct: 2928 VEDIWPLSPLQEGLFFHSSYDQSALDVYTAQDALDFDHRIDLERLRAACARLLHRNPSLR 2987

Query: 68   AAFWDRDVPKPVQIVPVHAA----------LPWSERVATPAEFDSIARSERRRPFDLSRG 117
            A F    + +PVQ +    A          LP  ER     E  S   ++RR  FDL+R 
Sbjct: 2988 AGFTSDGLSRPVQFIGTEPAMPLEVVDLGDLPEDERARRVGELMS---ADRRSRFDLARP 3044

Query: 118  PALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX 177
            P  R++++ + G  + R++ T H +L DGWS  +F  EL  +                  
Sbjct: 3045 PLCRLLLIRM-GPDRDRLVITHHLVLWDGWSEGLFLRELFTLYDRPDAELPAPGSYRD-- 3101

Query: 178  YIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWA 237
            Y+ WL +QD   A+  W   L G+ EP ++   +++  + P +  + LP     RLR+ A
Sbjct: 3102 YLAWLGRQDNDLAVRAWRHALSGLDEPTLLG-PSSSEPAIPEQLRVQLPEELCERLRRTA 3160

Query: 238  GRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHY 297
              HGLTLNT +   W +V S    R DVVFG+ VSGRP  +P VE ++G+F+N VPV   
Sbjct: 3161 REHGLTLNTVLNAVWGLVFSSAVGRNDVVFGSTVSGRPADIPDVENIIGMFLNTVPVRVT 3220

Query: 298  VSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPA 357
            +  TE+++    ++Q Q + +    Y+ L  +QRE G   LFDSL+V +N   +      
Sbjct: 3221 LDPTESLLELLRRIQSQRAELMPHDYVGLGVLQRETGHARLFDSLYVLQNFADESGFERL 3280

Query: 358  TTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLR 417
                G     V     THYPLT+V                    +  A  + ER  ++L 
Sbjct: 3281 REKFGIS--SVGSVDATHYPLTLVV-TPAARLGVMLAYRPDVIAHGDAQAMLERFTSLLE 3337

Query: 418  QLPDIGD-GTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXX 476
            +L    + GT D L      EL+      A   P  + TV +M   Q             
Sbjct: 3338 RLDLSAEVGTLDLLLPEERRELERDW--DAGRNPMSEETVADMLAAQAARTPDEVALVFG 3395

Query: 477  XGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVD 536
               R TYAEL AR  RLA  L   G GPE VVAL LPRS                YLP+D
Sbjct: 3396 EQ-RLTYAELDARINRLARLLLARGAGPERVVALGLPRSTEMVVALFAVLRTGAAYLPLD 3454

Query: 537  VTLPSARVESIVRQASPALAITEADYSQLV--GTAVPTLALDDPAAVESISRRSAA---- 590
            +  P+ R+  ++    P   ++    +  +    A   + +DDPA  E ++  S A    
Sbjct: 3455 LDHPADRLRMMIEDTEPVCLVSTTSVAPSLHGAPAEHRVLVDDPAVAEELAGLSGAGLAD 3514

Query: 591  ------APTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXX 644
                  AP    R E  AYVI+TSGSTG+PKGVV     + +   +H E V+        
Sbjct: 3515 AERPGFAPGTPDRMEHPAYVIYTSGSTGKPKGVVTPYRGLTNMQLNHQEAVFGPAIASAG 3574

Query: 645  XXXXXX-HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTP 703
                   H  S +FD SW+ ++ L++GHE+H+ D E  RDA+ LV       ID+++ TP
Sbjct: 3575 GRRLRIAHTVSFAFDMSWEELLWLVEGHEVHVCDEELRRDAEALVSYCDEHGIDVVNVTP 3634

Query: 704  SMFVQLSAAGLLD-HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXX 762
            +    L   GLL+ +  +++ LGGEA++  +W  LR       YN YGPTE T+      
Sbjct: 3635 TYAQLLIEEGLLEGYRPALVLLGGEAVSEAVWTSLRDTDGTYGYNLYGPTEYTINTLGAS 3694

Query: 763  XKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVA 822
              D   PT+G A   T  YV D  LR VP GV GELY++G  LARGY  R G+TA RFVA
Sbjct: 3695 TFDSDSPTVGRAIWNTRAYVLDPYLRPVPPGVPGELYIAGVGLARGYHRRFGLTAERFVA 3754

Query: 823  DPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDA 881
            DP   PG RMYRTGDLVRR   G   ++GR D QVKIRGYRVE+GEIE+AL   PGV  A
Sbjct: 3755 DPFGDPGDRMYRTGDLVRRRDDGNLDFLGRTDDQVKIRGYRVELGEIESALDSHPGVSQA 3814

Query: 882  AVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGK 941
            AV          LVG+VV      E    LR  L +RLP YMVPA ++T+ RLP+  NGK
Sbjct: 3815 AVVADTSTAVPRLVGYVVGPVADGE----LREHLKQRLPDYMVPAALMTVERLPLTVNGK 3870

Query: 942  LDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSI 1000
            LD  AL           +   +    T+ ERVLCELF + L A    IDDD F  G  S+
Sbjct: 3871 LDVKALPE-----PVPATAQDSRPPRTEAERVLCELFADVLGADQVGIDDDFFDLGGHSL 3925

Query: 1001 VAISLVHKARRQ-GLRVDPRMVLTATTIRQL------GAAIDAAVDSQDAPADADYG-AV 1052
            +A  L+ +AR      ++ R +  A T+ +L        A+  A+ +Q+ P +     A 
Sbjct: 3926 LATRLISRARTALAAELEIRDLFDAPTVAELVRRTGDREAVRPALVAQERPEEVPLSFAQ 3985

Query: 1053 RPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGP 1112
            R L ++  +    +   F   +++RL   +D  ++   +  +   H+ LR++       P
Sbjct: 3986 RRLWVIQQMEPDSSAYNF--PIVVRLRGELDLDALRAAVADVAARHEALRTVFGVRDGVP 4043

Query: 1113 --RLVTREPAAVRAEDVLTRITLPEGSDD---ELASAVAHAARVVTDQIDPSAGAMVRAI 1167
              R+V  E A    E V  R  + + + +   +LAS +     VV               
Sbjct: 4044 FQRVVPVEEARPVFEVVADRPGVVQEAIERPFDLASEIPLRVTVV--------------- 4088

Query: 1168 WFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRR 1227
                     +  ++++L  HH+  D  S    L DL+ A+ + + G  P   P    Y  
Sbjct: 4089 ------EAGEDEHVVVLLLHHITTDEWSDRPFLRDLSQAYAARRDGGEPGWEPLAVQYAD 4142

Query: 1228 WCELMWHRASAPQVQD-----QRDYW-AALVREPDPA-LGLRYPDPTRDTWSTLQLTRAA 1280
            +          P  +D     Q DYW   L   P+   L    P P R T          
Sbjct: 4143 YALWQQRTLGDPSDEDGLAASQLDYWHRTLAGAPEEVELPADRPRPARPT-----SAGGT 4197

Query: 1281 IPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL 1340
            + V++    +  + +D G    ++   A+     R    +D   G  +A    GR D  L
Sbjct: 4198 VEVELDCDGIRQLSQDSGASTFMVLHAAVGALLNRLGVGEDIPLGAPIA----GRTDEAL 4253

Query: 1341 DTDTTNTVGWFTNAFPVR 1358
            D    + VG+F N   +R
Sbjct: 4254 D----DLVGFFVNTLVLR 4267



 Score =  466 bits (1199), Expect = e-128
 Identities = 477/1530 (31%), Positives = 667/1530 (43%), Gaps = 148/1530 (9%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            LAL+  Q+G++ L Q  +     Y++ +  +I G ++++ +  +    +     L   F 
Sbjct: 6    LALTAAQDGIW-LSQQIDPETSAYNIAWYHEIRGELEVDRMTEAVGRAVREAECLHVRFR 64

Query: 72   DRDVPKPVQI--------VPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVV 123
            D     P QI        +PVH     ++ + T  E+    R++  RP DL  GP     
Sbjct: 65   DAG-GGPEQIAHPASGWRLPVHDLRAEADPLGTAEEW---MRADLSRPADLGGGPLFTHA 120

Query: 124  VLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLA 183
            +L V G+         HH+++D +  +V    +  +                     + A
Sbjct: 121  LLRV-GDRHFLWYQRYHHLVMDAYGFSVLSRRVGELYRGEGAAREWPVAALVESDARYRA 179

Query: 184  KQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRHGLT 243
                +A    W+  +    +P  +   A      P +T + LP    A L       G  
Sbjct: 180  SDSWAADREHWLARMADRPDPARLVTAA----GTPSRTSVELPEDRVAALCG----SGHR 231

Query: 244  LNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEA 303
            L+   + A A    RLT   DVV G  V+ R  +   V  MV    N +P+   V     
Sbjct: 232  LSRLAIAAVAAYTHRLTGETDVVLGLPVTARTAEHRDVPGMVS---NVLPLRLRVRPDMT 288

Query: 304  VVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDGA 363
                   V R+   +R        E+ RE G       L       +   +   +  DG 
Sbjct: 289  TAELVAAVDREVREVRAHERFRGEELARELGVPGGIAEL-------VGPTVNSMSFEDGL 341

Query: 364  QF--LPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQLPD 421
            +   L V   +L+  P+  +S                      AAE+GE     LR L  
Sbjct: 342  ELPGLDVRAHNLSLGPVNDLS-------VAVHDGPRGVRVDFDAAELGEHPARFLRVLEA 394

Query: 422  IGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEM-----FERQVQXXXXXXXXXXX 476
            I D  P  L        +   L+  R     D  V E+     FERQV+           
Sbjct: 395  ITDDRP--LHTIDPVPPEERRLVLDRFGRD-DRAVRELSWPAAFERQVRETPDAVAVVCE 451

Query: 477  XGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVD 536
               R TY EL+A A RLA  L   GVG E VVA+ +PRS                YLP+D
Sbjct: 452  DQQR-TYGELNAEANRLAHLLLAEGVGAEQVVAVAVPRSVEMVAALLAVLKTGAAYLPLD 510

Query: 537  VTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDR 596
            +  P  R+  ++R+AS  + + E       G   P + + D A       R A  P V+ 
Sbjct: 511  LDHPPDRIAFMLREASRVVTVPELAGELPPGP--PQVLVGDAAG------RPAQDPGVEV 562

Query: 597  RPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLS 656
            R +Q+AYVIFTSGSTG PKGVV T+  + S  A   +R+                  S+ 
Sbjct: 563  RLDQAAYVIFTSGSTGRPKGVVVTHDGIGSLVATAVDRLGVDAGSRVLQFA------SVG 616

Query: 657  FD-ASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQ-IDMIDTTPSMFVQLSAAGL 714
            FD A W+  + L  G  + +   E+ R A R +   A+   +  +   PS+   L A   
Sbjct: 617  FDVAVWELSMALCTGGRLVVVP-EQRRVAGRDLTDYAVEHGVTHLALPPSLVSALPADCE 675

Query: 715  LDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPT--IG 772
            L  + +VL +G E +   L +  R   ++ V   YG TE TV       +  R+ +  IG
Sbjct: 676  LPED-AVLLVGTEVVPAELIE--RWAKRLRVVVAYGLTEATVNSTLWMAEQGRRGSVPIG 732

Query: 773  TANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRM 831
              +  T  +V DSALR V  GV GE+Y++G  LARGY+GR G++A RFVADP   PG+RM
Sbjct: 733  RPDPNTRIHVLDSALRPVGVGVTGEIYVAGRGLARGYLGRRGLSAERFVADPFGEPGERM 792

Query: 832  YRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDR 891
            YRTGD  R    G  +++GR+D Q+KIRG+R+E GE+E+AL G P V  AAV + RQ  R
Sbjct: 793  YRTGDRARWRPDGTLSFLGRSDDQIKIRGHRIEPGEVESALMGHPDVVQAAV-LARQDHR 851

Query: 892  --TSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPR-LPVNANGKLDGHALD 948
              T LV +V    +   D   +RA     LP YMVP  +V L   LP+  NGK D  AL 
Sbjct: 852  GATRLVAYV----HGEADGAAVRAFAETLLPDYMVPNPVVVLAEPLPLTPNGKTDTAALP 907

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIVAISLVH 1007
                 AL      T     T  E    ELF E L+     + D  F  G DSIVAI LV 
Sbjct: 908  VPDWAALAGADRPT-----TAAEHHFAELFAEVLDLPSVGVHDSFFELGGDSIVAIELVS 962

Query: 1008 KARRQGLRVDPRMVLTATTIRQLGA-AIDAAVDSQDAPADADYGAVRPLPMVSWLYEY-G 1065
            +ARR G  + PR V    T   L A A +  + +Q   AD+  G V P P+V WL E  G
Sbjct: 963  RARRAGYAITPRQVFRQRTAAALAAVAQERGIAAQ--RADSGVGTVEPTPIVHWLRELGG 1020

Query: 1066 NYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSIL-----TETPEGPRLVTREPA 1120
               RF    LL  P+ +D   +  M+Q L+D HD LR+ L      E PE P        
Sbjct: 1021 EIERFHQWTLLTTPAELDHERLLEMVQALVDRHDVLRARLRPDWTLEVPEAP-------- 1072

Query: 1121 AVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPAN 1180
            AVRA DV+     P  +D+  + AV+  A        P  G ++R +WF         A 
Sbjct: 1073 AVRAGDVVETADGPV-TDEHRSWAVSGLA--------PREGRVLRVVWF-------PDAQ 1116

Query: 1181 ILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQ 1240
             LL+ AHHL +D VSW I+  DL  AW+ L AG   ++ P  TS R W  L+   A    
Sbjct: 1117 RLLMVAHHLVIDGVSWRILASDLELAWQQLSAGERVELPPVGTSLRTWSRLLREHA---- 1172

Query: 1241 VQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRR--DQG 1298
              D+R   A      D  LG R P   +DT +TL+     +P + TE +L +V       
Sbjct: 1173 -DDRRGESARWRHPADRGLGSR-PLDEQDTAATLRSLTVQVPAEQTEPLLSSVPAAFHGN 1230

Query: 1299 VRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL-DTDTTNTVGWFTNAFPV 1357
            V ++LL A A+AV  WR          +LV LEGHGR + V  D D T TVGWFT+ FPV
Sbjct: 1231 VDDVLLTALAVAVGRWR------GGGDLLVDLEGHGREEHVFGDVDLTRTVGWFTSLFPV 1284

Query: 1358 RLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDP 1417
            RL  G      + AE    +    V  V   L  +P+ GL YG LR++   AE   A   
Sbjct: 1285 RLNPG------DPAEFAAGSVDQAVKRVKEQLR-VPDGGLGYGQLRHL--AAEPGLAGGA 1335

Query: 1418 QIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQL 1477
             + F+YLGR  + G  D  W+    P  D L    +P +P+   L ++  V     G +L
Sbjct: 1336 PVLFNYLGRFSVRGGRD--WA--PAPEADPLGAGRDPRMPVDHELEINAVVRDDDGGPRL 1391

Query: 1478 IGNWRWSDAVFERSDIDHLTGLWQRGIAAL 1507
                 W + V   SD   L   W   + +L
Sbjct: 1392 SATLTWPEGVLAESDAAELGRGWVEALDSL 1421



 Score =  325 bits (832), Expect = 4e-86
 Identities = 403/1483 (27%), Positives = 609/1483 (41%), Gaps = 145/1483 (9%)

Query: 5    APQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHP 64
            A +  + + LS  Q  L+ + Q+  D    Y+   VV + G +DL+ LR +   +  RH 
Sbjct: 3972 AQERPEEVPLSFAQRRLWVIQQMEPDS-SAYNFPIVVRLRGELDLDALRAAVADVAARHE 4030

Query: 65   NLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVV 124
             LR  F  RD     ++VPV  A P  E VA   +   + +    RPFDL+    LRV V
Sbjct: 4031 ALRTVFGVRDGVPFQRVVPVEEARPVFEVVA---DRPGVVQEAIERPFDLASEIPLRVTV 4087

Query: 125  LSVPGETKRRMIFTAHHILVDGWSLAVFFTEL---LAVXXXXXXXXXXXXXXXXXXYIVW 181
            +   GE +  ++   HHI  D WS   F  +L    A                   Y +W
Sbjct: 4088 VEA-GEDEHVVVLLLHHITTDEWSDRPFLRDLSQAYAARRDGGEPGWEPLAVQYADYALW 4146

Query: 182  LAK-----QDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKP-------GKTELLLPAAD 229
              +      D     A  +DY            E  A + +P       G  E+ L   D
Sbjct: 4147 QQRTLGDPSDEDGLAASQLDYWHRTLAGAPEEVELPADRPRPARPTSAGGTVEVEL---D 4203

Query: 230  TARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFI 289
               +RQ +   G +    +  A   +L+RL    D+  G  ++GR D+   ++ +VG F+
Sbjct: 4204 CDGIRQLSQDSGASTFMVLHAAVGALLNRLGVGEDIPLGAPIAGRTDE--ALDDLVGFFV 4261

Query: 290  NAVPVVHYVSGT---EAVVAQCTQVQRQSSAMRDVSYLSLSEIQ---REHGRGPLFDSLF 343
            N + +   VSG    E ++A+  ++   + +  DV + ++ E     R  GR PLF  + 
Sbjct: 4262 NTLVLRTDVSGDPGFEELLARVRELDLAAFSHADVPFEAVVERLNPVRSPGRNPLFQVMV 4321

Query: 344  VFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYL 403
             + +           T  G +   +E+E            L                 Y 
Sbjct: 4322 SYHSR----------TAGGFELAGLEVEPEPFQTRAAKFDL-VFSFTEHADRITCCLEYA 4370

Query: 404  PAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVW------ 457
                  E +  + R+L  + D    D   R   EL  H     R    F+TT        
Sbjct: 4371 GDLFDRETVEALGRRLAVLVDAVVAD-PARPVGELDVH-TDDDRVLEEFNTTYRPVPELS 4428

Query: 458  --EMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRS 515
              E+F+RQV               R TY+EL  RA  +AG L   GV    VV + LPRS
Sbjct: 4429 FPELFQRQVLAAPDAVALVDGDR-RLTYSELDRRADGVAGVLLAAGVRRGDVVGVALPRS 4487

Query: 516  ERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTA--VPTL 573
              +             YLP+D++ P  R+  ++  +   + +T    +  V  A  V  L
Sbjct: 4488 VENVATMLAALKLGAAYLPLDLSYPRERLSYVLTDSGAGVVVTTRAEADRVPAADGVELL 4547

Query: 574  ALDDPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAE 633
             LD+ A    ++      P +D     +AYVI+TSGSTG PK VV  +  + S  A   +
Sbjct: 4548 VLDEVADEPGVAL--PPPPGLD----DAAYVIYTSGSTGRPKAVVVPHDGIASLVATAVD 4601

Query: 634  RVYXXXXXXXXXXXXXXHAWSLSFD-ASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIA 692
            RV                  S +FD A ++  + L  G  + L   +     + L + + 
Sbjct: 4602 RVGVTAESRVLQFA------SPAFDVAVFETAMALCVGGRLVLVPEQARVAGEPLTDLLL 4655

Query: 693  IGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPT 752
               I      P++   L A   L   ++VL +G EA+   L ++  G +++ V   YG T
Sbjct: 4656 EQGITHAALPPALLAALPAPCRLPEGITVL-VGTEAVPPHLIERWAGHARLVV--AYGLT 4712

Query: 753  EMTVEXXXXXXKDYRKPT-IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVG 811
            E TV       +       IG  +  T  +V D+ LR VP GV GELY++G  LARGY+G
Sbjct: 4713 EATVNSTLWTAEPGTGTVPIGRPDPNTQAHVLDANLRPVPLGVPGELYIAGRGLARGYLG 4772

Query: 812  RPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEA 870
            R G+TA RFVA P   PG RMYRTGD VR    G   ++GR D Q+KIRG+RVE GE+EA
Sbjct: 4773 RHGLTAERFVACPFGEPGTRMYRTGDRVRWRRDGTLDFLGRVDEQIKIRGFRVEPGEVEA 4832

Query: 871  ALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVT 930
            AL   P V  A V      + + L+G+VV +  +  D  +LR  ++  LP +MVPA +V 
Sbjct: 4833 ALVAHPAVRQAVVVA---DEGSRLIGYVVPEGQV--DTAELRTHVSGLLPEHMVPAAVVE 4887

Query: 931  LPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPH--I 988
            L R+P++ NGK+D  AL      A+T          +T  +R L ELF E L  +P   +
Sbjct: 4888 LDRIPLSPNGKVDRRALPAPDWSAMTGDD-----RPATAQQRALAELFAEVL-GLPEVGV 4941

Query: 989  DDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADA 1047
             D  F  G  S+ A+ L+   R      +  R V  A T+  L   I A+ ++  AP  A
Sbjct: 4942 HDGFFALGGHSMAAMRLLGAIRSVFAAELTVRDVFDAPTVAALAGKI-ASAEAGRAPLRA 5000

Query: 1048 -DYGAVRPL--PMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSI 1104
             +  A  PL  P       YG++    H ++LR  SG+D  ++   L+ ++  H+ LR++
Sbjct: 5001 GERPAELPLAPPQRHRWSRYGDFPGHDHALVLR-TSGMDADALASALRDVVARHEPLRTV 5059

Query: 1105 LTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMV 1164
            + E          +   +   DV        G  DE  + +A  A  + +Q    A  +V
Sbjct: 5060 VVERDGQAYQQLVDGPELEVLDV-------TGDLDERVAELAREAPDLREQSPLRARLLV 5112

Query: 1165 RAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTS 1224
                        D    LLLT H+L +D  S   +  DLAAA+ + + G  P   P   S
Sbjct: 5113 ----------APDGGQRLLLTMHYLGIDEWSTVPLFRDLAAAYAARREGAVPDRAPLPVS 5162

Query: 1225 YRRWCELMWHRASAPQVQDQRD-----YW-AALVREPDPALGLRYPDPTRDTWSTLQLTR 1278
            Y  +    W     P     R      YW  AL   P+  L +  P              
Sbjct: 5163 YADYTRWAWEVLGDPADPGSRHARQLRYWREALAGMPELPLPVDRP-RAGSRGGRGDFVE 5221

Query: 1279 AAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADA 1338
              I  +  E +    +R  G    ++   A+A    R    +D   G   A    GR++ 
Sbjct: 5222 FVIDAEEHEEIDRLAQR-SGASMFMVLHAALAALLTRLGAGEDLPIGTFTA----GRSED 5276

Query: 1339 VLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLD 1398
             L    T+ VG F N   +R               DP  A+     ++  +       LD
Sbjct: 5277 SL----TDLVGCFFNTVVLR----------TDTTGDPTFAE-----LLGRVRETALSALD 5317

Query: 1399 YGLLRYVDGVAELVDAVDPQI-----QFSYLGRLDLGGVADQP 1436
               L + D + E+  A  PQ+     + + L  LD GG++  P
Sbjct: 5318 RQELPFDDVLREVPSARAPQVLLVHHEQANLTALDEGGLSAVP 5360


>tr|Q7WZ74|Q7WZ74_9ACTO Tax_Id=93944 (dbv17)SubName: Full=Putative
            non-ribosomal peptide synthetase, modules 4-6;[Nonomuraea
            sp. ATCC 39727]
          Length = 4083

 Score =  694 bits (1790), Expect = 0.0
 Identities = 527/1536 (34%), Positives = 755/1536 (49%), Gaps = 96/1536 (6%)

Query: 4    AAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRH 63
            A  +IED   LSPLQ+GL       +D   LY   ++++++GPV+ + LR + +A+L RH
Sbjct: 2    AQSRIEDFWPLSPLQQGLLFHTTYDDDWPGLYVGHWILNLNGPVEADRLRAAWEALLARH 61

Query: 64   PNLRAAFWDRDVPKPVQIVPVHAALPWS----ERVATPAE-FDSIARSERRRPFDLSRGP 118
              LRA F  R   + VQ++     LPW       ++ P E   ++A  +R R FDL++ P
Sbjct: 62   AALRACFRQRKSGETVQLIARQVELPWRVVDLSHLSEPEEAVRAVAEEDRTRRFDLAKAP 121

Query: 119  ALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY 178
             LR+ ++ + G+   R++ T HH ++DGWS+ +   EL  +                  Y
Sbjct: 122  LLRLTLIRLAGDD-HRLVMTCHHAIMDGWSMPIMLDELSMLYAADGSPLDLPAVPSYRDY 180

Query: 179  IVWLAKQDRSAALAGWMDYLRGVSEPLMVA-YEATAGQSKPGKTELLLPAADTARLRQWA 237
            +VWL +QD+   L+ W   LRGV EP +VA  +A    + P    + LP   T  L + A
Sbjct: 181  LVWLDRQDKERTLSAWAAELRGVEEPTLVAPADANRAPAMPENITVELPEDLTRALSELA 240

Query: 238  GRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHY 297
              HGLTLNT V  AWA++L++L  R DVVFG  VS RP  LPGVE MVGLF+N VPV   
Sbjct: 241  RTHGLTLNTVVQGAWALLLAQLAGRTDVVFGAAVSARPPDLPGVEGMVGLFLNTVPVRVR 300

Query: 298  VSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPA 357
            +SG+  V+     +Q++ SA+    Y+ L++IQR  G G +FD+L VF+N P +  +RP+
Sbjct: 301  LSGSTPVIEFLADLQKRQSALIPHQYMGLADIQRTAGAGAVFDTLLVFQNFPRE--LRPS 358

Query: 358  TTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLR 417
                       +     HYPLT+V+ +                    A  I ER   +LR
Sbjct: 359  DAAAAFDIRIDQGREAAHYPLTLVA-VPGESMLLNLDHVTDLFDREAALAILERFTGILR 417

Query: 418  QLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTF--DTTVWEMFERQVQXXXXXXXXXX 475
            QL   GD T  ++D+ +AAE +A  + A  +AP         ++F+RQV+          
Sbjct: 418  QLAGAGDLTVAEVDVTSAAE-RALVVNAWSAAPRVAPGELAPDLFDRQVERGRDRVAVVE 476

Query: 476  XXGVRH-TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLP 534
              G R  ++ EL   A RLAG L+  GV     VA+V+ RS                ++P
Sbjct: 477  --GKRAVSFGELAEHAERLAGYLSGRGVRRGDRVAVVMGRSPGLIATLLAVWKAGAAFVP 534

Query: 535  VDVTLPSARVESIVRQASPALAITE-ADYSQLVGTAVPTLALDDPAAVESISRRSAAAPT 593
            VD   P+ RV+ ++  A PA  +TE A  + +    +  + LDDP  + +++    A  +
Sbjct: 535  VDPAYPAERVQFMLADAEPAAVVTERACQAAVPAGGLDPIVLDDPDTLRAVAEH--ARLS 592

Query: 594  VDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAW 653
                 +  AYV++TSGSTG PKGV  ++  V +   +                    HA+
Sbjct: 593  AGAHADDLAYVMYTSGSTGRPKGVAVSHGNVAALAGEPG----WGLGPEDAVLMHASHAF 648

Query: 654  SLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQL---- 709
             +S    W P   LL G  + L +   + D + L  G   G +     T   F  L    
Sbjct: 649  DISLFELWVP---LLSGARVVLAEPGAV-DGEALA-GYVAGGVTCAHLTAGTFRVLAEES 703

Query: 710  --SAAGLLDHNLSVLALGGEAINTGLWDQLR-GLSQMAVYNCYGPTEMTVEXXXXXXKDY 766
              S AGL +     +  GG+A+     +++R     + V + YGPTE T+       +  
Sbjct: 704  PESVAGLRE-----VLTGGDAVPLAAVERVRRACPDVRVRHLYGPTEATLCATWWLLQP- 757

Query: 767  RKPT-----IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFV 821
             +PT     IG   AG   YV D+ LR VP GV GELY++GA +A+GY+GRP +TA RFV
Sbjct: 758  GEPTGPVLPIGRPLAGRRVYVLDAFLRPVPPGVTGELYVAGAGVAQGYLGRPALTAERFV 817

Query: 822  ADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDA 881
            A+P  PG RMYRTGDL R    G  A+ GRAD QVKIRGYRVE GEIEA L G PGV  A
Sbjct: 818  AEPFVPGGRMYRTGDLARWTDQGELAFAGRADDQVKIRGYRVEPGEIEAVLAGLPGVGQA 877

Query: 882  AVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGK 941
             VS   ++    L+G+VV +     D +++R  L   LP +MVPA ++ L  LP+  NGK
Sbjct: 878  VVSAREER----LIGYVVAETGGDLDPVRIREQLAATLPEFMVPAAVLVLDALPLTGNGK 933

Query: 942  LDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSI 1000
            +D  AL           +G      +TD ER+LC +F E L A    + D  F  G DSI
Sbjct: 934  VDRRALPE-----PDFAAGAVDREPATDAERILCGVFAEVLGAGRVGVADSFFELGGDSI 988

Query: 1001 VAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSW 1060
             ++ +  +ARRQG+ + PR V    T  +L A    A   + +  +   G +   P++  
Sbjct: 989  SSMQVAARARRQGIPLTPRQVFEHRTPERLAALAQQAPGRRASSVEPGVGEIPRTPVMRA 1048

Query: 1061 LYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPA 1120
            L +      F    ++  P+G    ++   LQ +LD HD LR+ +   P+G RL+  EP 
Sbjct: 1049 LGDDAVRPGFAQARVVVTPAGFAPDALVTALQAVLDVHDLLRTRV--EPDG-RLMVAEPG 1105

Query: 1121 AVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPAN 1180
            AV A  ++TR+    G+   LA      AR     +DPS G MVRA+W    +  A+P  
Sbjct: 1106 AVDAAGLVTRVAAGNGN---LAERAEREARTAAGTLDPSEGIMVRAVWVDAGD--AEPGR 1160

Query: 1181 ILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQ 1240
             L L  HHL VD VSW I+L DL AA+    +G  P + P  TSYR+W   +  +A +  
Sbjct: 1161 -LALVVHHLVVDAVSWAILLSDLRAAYDEAVSGGTPVLEPAVTSYRQWARRLAGQALSES 1219

Query: 1241 VQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVR 1300
               +  +WA ++   D  L  R+P  +     TL   +A    ++  RV  A     GV+
Sbjct: 1220 TVAEAGHWAGVLEGGDLPLE-RHPGQSASWSRTLSDAQAR---NLVARVPAAFH--CGVQ 1273

Query: 1301 ELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLG 1360
            ++LLA  A AVA WR        AG+LV +EGHGR  A    D   TVGWFT+  PVRL 
Sbjct: 1274 DVLLAGLAGAVARWR-----GADAGILVDVEGHGR-HAADGEDLLRTVGWFTSVHPVRL- 1326

Query: 1361 AGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQ 1418
                  D+        AA +L+ +V     A+P DGL YGLLRY+  +  A L +    Q
Sbjct: 1327 ------DVSGVGPGAAAAGELLKAVKEQARAVPGDGLGYGLLRYLNPETGARLAELPSAQ 1380

Query: 1419 IQFSYLGRLDLGGVA--DQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQ 1476
            I F+YLGR    GVA  D  W +  G           PDL    AL +   V  T  G +
Sbjct: 1381 IGFNYLGR---SGVASEDTAWQVCEGALGGQA---AGPDLVQSHALEVGADVQDTPAGPR 1434

Query: 1477 LIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD 1512
            L           + + ++ L   W   +A LAA  D
Sbjct: 1435 L--RLAIDGRDLDPAAVERLGEAWLDTLAGLAALAD 1468



 Score =  613 bits (1581), Expect = e-173
 Identities = 500/1551 (32%), Positives = 719/1551 (46%), Gaps = 110/1551 (7%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            A AP + DV  LSPLQEG+       EDGVD+Y  Q ++D+DGP+D + L  + Q+++DR
Sbjct: 1495 AVAPGLTDVWPLSPLQEGILFERAFDEDGVDVYQTQRILDLDGPLDAQRLHAAWQSVIDR 1554

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWSE----RVATP-AEFDSIARSERRRPFDLSRG 117
            H  LR  F      + VQ+V   A + W E    R+  P AE + +  +++   FD+SR 
Sbjct: 1555 HETLRTGFHQLGSGETVQVVVGEAEVLWREADLSRLDEPDAEVERLLAADQAERFDVSRA 1614

Query: 118  PALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX 177
            P LR++++ + G  + R++ T+HH+LVDGWS  +   E+L                    
Sbjct: 1615 PLLRLLLIRL-GAARHRLVVTSHHVLVDGWSTPILLGEMLTAYADGRVSPAPPSYRD--- 1670

Query: 178  YIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWA 237
            Y+ WL++QD  AA + W   L G+ EP +V  +A      P      L    T  L  +A
Sbjct: 1671 YVAWLSRQDEDAARSAWRAELAGLDEPTVVGLDAGKAPVMPDGHAEWLSEEATRALTGFA 1730

Query: 238  GRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRP-DQLPGVETMVGLFINAVPVVH 296
              HGLTL+T V  AWA+VL+RL  R DVVFGTVVSGRP D LP VE MVG+FIN VPV  
Sbjct: 1731 RGHGLTLSTVVQGAWALVLARLARRTDVVFGTVVSGRPADALPDVERMVGMFINTVPVRV 1790

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRP 356
             + G   V+     +QR+ S++ +  +L L EIQ+  G G +FD++ +  N P+D     
Sbjct: 1791 RLDGAVPVLDLLQDLQRRQSSLTEHQHLGLPEIQKAAGPGSIFDTILMIVNYPLD---AD 1847

Query: 357  ATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLP-------AAEIG 409
                 G     +   + T YPL+V                     Y P       AAEI 
Sbjct: 1848 GLDDGGVAISSIRTRTGTTYPLSV--------SVIPGARLQIQLDYRPDWIGGDLAAEIT 1899

Query: 410  ERMLTVLRQL---PDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQX 466
             +++ VL ++   P +  G        T   +       +  A    ++V E+F RQ   
Sbjct: 1900 GQVVRVLARMVAEPSLPVGRLAVTSRSTRGSVTERW--NSTGAAAGGSSVPELFRRQADA 1957

Query: 467  XXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXX 526
                       G   +YA L   + RLAG LA  GV     V +++ R            
Sbjct: 1958 APDATAVIGD-GRTLSYAGLDRESDRLAGHLARRGVRRGDRVGVLMERGADLIVALLAVW 2016

Query: 527  XXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISR 586
                  +PV+V  P+ R+E ++  A  ++A+        V   +  + +D PA       
Sbjct: 2017 KAGAAQVPVNVDYPAERIERMLADAGASVAVCAGATRHAVPDGIEPVVMDAPAT----EA 2072

Query: 587  RSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXX 646
                AP +       AYV++TSGSTG PKGV   + +  +   D                
Sbjct: 2073 ERHEAPPLAVGAHDVAYVMYTSGSTGVPKGVAVPHGSAAALAGDPG----WSQGAGDRVL 2128

Query: 647  XXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMF 706
                HA+  S    W P+V    G  + + +   + DA RL + IA G   +  T  +  
Sbjct: 2129 MHASHAFDASLLEIWVPLVS---GACVMVAEPGAI-DAQRLRDVIARGATTVHLTAGTFR 2184

Query: 707  VQLSAAGLLDHNLSVLALGGEAINTGLWDQLR-GLSQMAVYNCYGPTEMTVEXXXXXXKD 765
            V    +      L  +  GG+ +      ++R    ++ V   YGPTE+T+       + 
Sbjct: 2185 VLAEESPDSFSGLREVLTGGDVVPLESVARVRRACPEVRVRELYGPTEVTLCATWHLIEP 2244

Query: 766  YRKP----TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFV 821
            + +      IG   AG   YV D+ L+ V   V GELYL+GA LA GY+G P  T+ RF+
Sbjct: 2245 HTETGDTLPIGRPLAGRQVYVLDAFLQPVAPNVTGELYLAGAGLAHGYLGAPAATSERFI 2304

Query: 822  A-----DPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQP 876
            A     +P   G+RMYRTGDL R    G   + GRAD+QVKIRGYRVE GEIEAAL   P
Sbjct: 2305 AVPASVNPAASGERMYRTGDLARWTDRGELLFAGRADSQVKIRGYRVEPGEIEAALAEVP 2364

Query: 877  GVHDAAVSVLRQQDRTS---LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPR 933
              H A   V+ ++DR     L+ +V  ++    D   +R  L  RLP +MVPA +V L  
Sbjct: 2365 --HVAQAVVVAREDRPGEKRLIAYVTAEEGSGLDPDAVREHLAGRLPEFMVPAAVVLLDG 2422

Query: 934  LPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDL 992
            +P+  NGK+D  A   L     T  + G      T+ ERVLCELF E L  A    +D  
Sbjct: 2423 VPLTPNGKIDRAA---LPVPEFTGKAAGR--EPRTEAERVLCELFAEVLGVARAGAEDSF 2477

Query: 993  FLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAV 1052
            F  G DSI+++ L  +ARR+ L    + V    T   + A +     +  A  D   G V
Sbjct: 2478 FELGGDSILSMRLAARARREELVFGAKDVFERKTPAGI-AMVAERGGATRASLDDGVGEV 2536

Query: 1053 RPLPMVSWLYEYG----NYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTET 1108
               P++  L E           +  V    P  +    +   L  ++D HD LRS +  T
Sbjct: 2537 MSTPVIRALLERDPDAMTRGALSQWVTAGAPDDLSVDVLAAGLGAVIDAHDMLRSRIVRT 2596

Query: 1109 PEG-PRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAI 1167
                PRLV     AV A  ++ R+    G  DE+A      AR    ++DP AG M+RA+
Sbjct: 2597 GAAQPRLVVAGRGAVDAATLVERVEAGTGDVDEIAD---RCARDAAARLDPHAGVMIRAV 2653

Query: 1168 WFRGTEHRADPANI--LLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSY 1225
            W       A P  +  L++ AHHL VDVVSW I+L DL  A  ++ AG  P + P   S+
Sbjct: 2654 WV-----DAGPGRVGRLVVAAHHLVVDVVSWRILLPDLQVACEAVAAGRRPVLDPVDVSF 2708

Query: 1226 RRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVD- 1284
            RRW   +  +A       + + W  ++      LG    DP RDT ST   T   +P D 
Sbjct: 2709 RRWARTLADQAVTRAT--ELETWTEILDGARSRLG--ELDPARDTVSTAGRTSWTLPHDR 2764

Query: 1285 ---VTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLD 1341
               + E+   A     GV E+LLA  A AVA WR          V+V +EGHGR   + +
Sbjct: 2765 AGVLVEQATSAFH--CGVHEVLLATLAGAVAHWR------GGTAVVVDVEGHGRR-PIDE 2815

Query: 1342 TDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGL 1401
             D + TVGWFT+  P+RL      +D  +      AA  L+  V  ++ A+P+ GL YG+
Sbjct: 2816 LDLSRTVGWFTDVHPLRL--DVTGIDPAEVIAGGGAAGHLLKQVKENVRAVPDGGLGYGI 2873

Query: 1402 LRYVD-GVAE-LVDAVDPQIQFSYLGRL-DLGGVADQPWSLLTGPYLDALPIDPEPDLPL 1458
            LRY++ G  + L  A  P+I F+YLGR       A +PW L     L  +    E D  L
Sbjct: 2874 LRYLNAGTGQALAAAPKPEIGFNYLGRFPSRSAGAPEPWQL-----LGTIGGTAEQDTAL 2928

Query: 1459 RFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            R A+ +   V   A G +L     W+  +   ++ + L   W   +  LAA
Sbjct: 2929 RHAVEIDAAVLDGAAGPELSLTVTWAGRLLGEAEAESLAQAWLAMLTGLAA 2979



 Score =  446 bits (1148), Expect = e-123
 Identities = 368/1106 (33%), Positives = 513/1106 (46%), Gaps = 88/1106 (7%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            V AA P + D+  LSPLQEGL   H   E G D+Y+    + +DGP+D+   R S QA+L
Sbjct: 3007 VEAAVPTLLDIWPLSPLQEGLL-FHAADERGPDVYAGMRKLALDGPLDVARFRASWQALL 3065

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATP-------AEFDSIARSERRRPFD 113
            DRHP LRA+F        VQ +     L W E   +        AEFD +A       FD
Sbjct: 3066 DRHPALRASFHQLGSGAAVQAIAREVPLDWQETDLSRLPEDEALAEFDRLAEQLHTERFD 3125

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            L+R P LR+ ++ + GE + R++ T+HHI+ DGWSL +   ++L V              
Sbjct: 3126 LTRAPQLRLHLVRL-GERRHRLVLTSHHIVADGWSLPLITEDVLTVYESGGDGRALPAAT 3184

Query: 174  XXXXYIVWLAKQDRSAALAGWMDYLRGVSEPL-MVAYEATAGQSKPGKTELLLPAADTAR 232
                Y+ W+A+QD++AA   W   L G+ E   +V  E      +P +    L  A + R
Sbjct: 3185 SYRDYLAWIARQDKAAAREAWRAELAGLDEATHVVPPETITTPLEPERVGFELDEALSRR 3244

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            + ++ GRHG+T NT     WA+ L+RLT R DVVFG  V+GRP ++PGVE+ VGLF+N +
Sbjct: 3245 VVEFTGRHGVTANTLFQGIWALHLARLTGRDDVVFGAAVAGRPPEIPGVESAVGLFMNML 3304

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDD 352
            PV   ++G E  +   T +Q +  A     ++ LSEI +  G G  FD++ VFEN P   
Sbjct: 3305 PVRARLAGAEPFLDMLTDLQERQVACMPHQHVGLSEINQLAGPGAAFDTIVVFENYP--- 3361

Query: 353  AIRPATTPDGAQFLPVEMESLT----HYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEI 408
               P   P+G   L +    +     HYPL+    +R                 +  AE 
Sbjct: 3362 --PPPPRPEGPDALVMRPAGIPNDTGHYPLS----MRASVAGRVHGEFIYRPDVVDRAEA 3415

Query: 409  GERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAAR----SAPTFDTTVWEMFERQV 464
             E + ++LR L  +       +        +   L+         P     V  +F RQV
Sbjct: 3416 EEMLASILRALEQVVAEPRVPVGRVGLIGPEQRRLVVEEWNRTGVPPAAEPVPMLFRRQV 3475

Query: 465  QXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXX 524
            +                +Y+ L   A  LA  L   GV  ET V +++ RS         
Sbjct: 3476 ERSPDAVAVVDAARSL-SYSGLLDEAEELARLLVGLGVRRETRVGVLVGRSAELVVALLG 3534

Query: 525  XXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGT--AVPTLALDDPAAVE 582
                   ++P+D   P  R+  I+  ++P + +  ++  Q V    A   +ALD P A +
Sbjct: 3535 VSSAGGVFVPMDPDYPRERISFILADSAPEVLLCTSETRQAVPEEFAGAVVALDAPLAAD 3594

Query: 583  SISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXX 642
                   A P V+      AYVI+TSGSTG PKGV+  +A + +  +   ER        
Sbjct: 3595 P----RTALPRVEAG--DGAYVIYTSGSTGVPKGVLVPHAGLGNLASAQIERFGVTSASR 3648

Query: 643  XXXXXXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDT 701
                       +L FDA+   + + LL G  + L DAE M     L + +    I  +  
Sbjct: 3649 ILQFA------ALGFDAAVSELCMALLSGGTVVLADAESMPPRVSLGDAVRRWGITHVTV 3702

Query: 702  TPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXX 761
             PS+    +    L  +L  L + GEA    L D+     +M   N YGPTE TV     
Sbjct: 3703 PPSV---PAVEDDLPDSLETLVVAGEACPPALVDRWSPGRRMI--NAYGPTETTVCATMS 3757

Query: 762  XXKDYRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAAR 819
                  +    IG    G   YV D+ L+ VP GV GELY++GA LARGY+GRPG+TA R
Sbjct: 3758 SPLSPGRDVVPIGRPITGLRAYVLDAFLQPVPPGVTGELYVAGAGLARGYLGRPGLTAER 3817

Query: 820  FVA-----DPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRG 874
            FVA      P RPG+RMYRTG+  R    G   + GRAD QVK+RGYR+E GEIEA L  
Sbjct: 3818 FVAVPASVSPARPGERMYRTGNRARWTRDGELVFTGRADAQVKVRGYRIEPGEIEAVLAD 3877

Query: 875  QPGVHDAAVSVLRQQD---RTSLVGFVV-------------WQDNMHEDLIKLRAGLTER 918
             PGV  A V+V+ ++D   +  LV +VV              QD     +  LR     R
Sbjct: 3878 HPGV--AQVAVVAREDGPGQKYLVAYVVPAAEQVAGAPSEAGQDGAL--ISALRESAAGR 3933

Query: 919  LPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELF 978
            LP +M PA  V L  +P+  NGK+D  AL   A D   S SG    SA    E  LCELF
Sbjct: 3934 LPEHMRPAAFVPLDTMPLTPNGKVDHRAL--RAPDFARSSSGRDPRSA---MEAKLCELF 3988

Query: 979  EEQLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAA 1037
             E L        D  F  G DSI ++ L   ARR+GL + P  V    T  +L A +   
Sbjct: 3989 AEVLGLEEVGAGDSFFELGGDSITSMQLSALARRKGLDLTPWQVFDEKTAERLAAVV--- 4045

Query: 1038 VDSQDAPADADYGAVRPLPMVSWLYE 1063
               ++ PAD + G   P P    L +
Sbjct: 4046 ---KELPADGE-GTGEPEPPAGTLVD 4067


>tr|Q0S1Z9|Q0S1Z9_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal
            peptide synthetase; EC=5.1.1.13;[Rhodococcus sp.]
          Length = 5496

 Score =  688 bits (1775), Expect = 0.0
 Identities = 513/1556 (32%), Positives = 738/1556 (47%), Gaps = 78/1556 (5%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AA P + DV  L+PLQ GL     LA   VD+YSMQ V  + G VD   L  +AQA+LDR
Sbjct: 1557 AAYPAVTDVWPLTPLQSGLLFHALLAASSVDVYSMQVVFTLTGRVDATRLHAAAQAVLDR 1616

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWSE-------RVATPAEFDSIARSERRRPFDLS 115
            HPNLR AF       PVQ+V     +PW E         A P     +  +++ R FD++
Sbjct: 1617 HPNLRVAFVGGADGIPVQLVLDKLPVPWREVDLRDVDDAARPDALTRLLAADQARHFDMT 1676

Query: 116  RGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXX 175
              P +R  +++   E +  ++   HHIL+DGWS+ +  T+LLA+                
Sbjct: 1677 APPLIRFTLVTA-AEDRYELVVANHHILLDGWSMPLLMTDLLALYAAGDEASALPPARPY 1735

Query: 176  XXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQ---SKPGKTELLLPAADTAR 232
              Y+ W A+QD +A+   W   L GV  P ++A  A  G+   S+ G+    L    T  
Sbjct: 1736 RSYLEWRAEQDEAASRRAWAAALEGVDGPTLLA-PADPGREISSRAGEVAADLGEQRTRA 1794

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L + A R  +T+NT +  AW +++ R+T R D VFG+ VSGRP QL GVE+M+GLFIN V
Sbjct: 1795 LSELAARLDVTVNTVMQAAWGILMMRMTGRDDTVFGSTVSGRPPQLTGVESMIGLFINTV 1854

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGR-GPLFDSLFVFENAPID 351
            PV       E +    T++ R+ + + D  YL L+EIQ+  G    LFD+L VFE+ P++
Sbjct: 1855 PVRVRADPDETITQLLTRMHREQADLLDHLYLGLTEIQQSAGTTDTLFDTLTVFESYPVE 1914

Query: 352  DAI--RPATTPDGAQFLPVEMESLTHYPL----TVVSHLRXXXXXXXXXXXXXXXPYLPA 405
             A     A   DG     V     THYPL    TV + +R               PY+ A
Sbjct: 1915 QATLTEQADALDGITLAGVNANDNTHYPLALKITVDTQIRLSLTYLHDLFDE---PYVQA 1971

Query: 406  AEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQ 465
              +  R L +L  +         D+DI    E +   LL     P    T          
Sbjct: 1972 --LLHRYLRLLGAIIADAGSPVGDIDILDPDERR--NLLDRTGGPEHPATTLPQLLTTAA 2027

Query: 466  XXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXX 525
                            +Y +L   + +LA  L   G+G E  VA+ LPRS  +       
Sbjct: 2028 AHDRTAPAVIYRDHHLSYEQLDTASSQLARILIAEGIGTENTVAIALPRSPDAILAVWAT 2087

Query: 526  XXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESIS 585
                  +LP+D   P  R+  ++  +  AL +T  +++  +   +P L +D P  +++  
Sbjct: 2088 TKTGAAFLPIDPNYPKDRITHMLSDSRAALGLTTTEHATTLPGPLPWLVIDTPD-IQTRC 2146

Query: 586  RRSAAAPTVDR---RP---EQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXX 639
                  P  D    RP     +AY+++TSGSTG PKGVV T+  + +  A+  ER     
Sbjct: 2147 NTIDPGPITDADRLRPLHTTNTAYLLYTSGSTGTPKGVVVTHQGLANLAAEQHERFTTTP 2206

Query: 640  XXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMI 699
                          S SFDAS   ++         +     +   D L   +    I   
Sbjct: 2207 HSRTLAVA------SPSFDASVFELLLAAGTGATMVIAPPTVFGGDELTHLLHTNHITHA 2260

Query: 700  DTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGL---W----DQLRGLSQMAVYNCYGPT 752
              TP+    +    L  H L  +   GEA    L   W    D     +    +N YGPT
Sbjct: 2261 VITPAALATIDPTHL--HTLHTVLSAGEACTPDLLTRWTTHTDTSPTHTPRRFFNGYGPT 2318

Query: 753  EMTVEXXXXXXKDYRKP-TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVG 811
            E TV            P TIG    GT  YV D  LR VP GV  EL+L+G QLARGY  
Sbjct: 2319 ETTVMSNCSGPLPPGGPITIGGPIRGTHAYVLDDRLRPVPTGVTAELHLAGIQLARGYHN 2378

Query: 812  RPGMTAARFVADPLRP-GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEA 870
            RP +TA RFVA+P  P G+RMYRTGDLVR    G   ++GR D Q+K+RG+R+E+ EIEA
Sbjct: 2379 RPALTAERFVANPYGPPGERMYRTGDLVRWHPDGTLEFLGRRDLQIKLRGHRIELAEIEA 2438

Query: 871  ALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVT 930
             L   P +  AAV+V +      LV +VV       D  ++RA   +RLP YM+P  I  
Sbjct: 2439 TLTTHPDITHAAVTVHKGPVTEQLVAYVVPTPGAQIDPARVRAFAADRLPDYMLPDPITV 2498

Query: 931  LPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEE--QLNAVPHI 988
            L RLP+  NGK+D  AL   A                T TE+ + ++F +  +L+ V  +
Sbjct: 2499 LDRLPLTPNGKIDRRALPAPAP------LNRQFRPPVTPTEQTIADVFTDVLELDRV-GV 2551

Query: 989  DDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDS--QDAPAD 1046
            D+  F  G DSIVAI LV +A+ +G+    R V    T+  L        DS    A  +
Sbjct: 2552 DESFFALGGDSIVAIQLVSRAKARGVVFSSRDVFERRTVSGLAEVAQRPEDSGLPVALEE 2611

Query: 1047 ADYGAVRPLPMV----SWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLR 1102
               G +  +P+     + +   G + RF+  +L+ LP GI+R  +   ++ +LD HD  R
Sbjct: 2612 LPGGGIGWMPLTPVARALIERGGGFGRFSQHMLVELPPGIERGELVATIEAVLDHHDIFR 2671

Query: 1103 SILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHA-ARVVTDQIDPSAG 1161
            S L     G  L      A+  + ++ R+ +    D+E A+A+A A       ++ P+ G
Sbjct: 2672 SRLVGDERGWGLEVGGSDAIDVDGLVRRVEVTADLDEEAAAALASAQLDAALGRLAPTTG 2731

Query: 1162 AMVRAIW--FRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKIL 1219
             MV+ +W  FR     A     LL+ AHHL +D VSW I+L DLA+AW  + AG  P + 
Sbjct: 2732 VMVQFVWLDFRSECSTAQRPGRLLIVAHHLVIDGVSWRIILPDLASAWAQVSAGHTPVLD 2791

Query: 1220 PEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRA 1279
            P  TS RRW   +   +SAP    +   W AL++ PDP LGLR  +   D  STL     
Sbjct: 2792 PAGTSMRRWSHALVEESSAPARLAELPMWQALLQAPDPVLGLRPFNAAIDVGSTLDRVEV 2851

Query: 1280 AIPVDVTERVLGAVRR--DQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRAD 1337
            ++P      +L  +      GV + LLAA A+AV  WRR R Q   +  L+ LEGHGR +
Sbjct: 2852 SVPAPAVASLLTTLPTLFHGGVEDGLLAALALAVCRWRRAR-QVSESSTLIQLEGHGRQE 2910

Query: 1338 AV-LDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDG 1396
             +    D + TVGWFT  FPVRL  GAA  D+++A     AA  +V S+   L +IP+ G
Sbjct: 2911 QIAAGADLSRTVGWFTTVFPVRLDIGAA--DLDEAFAGGAAAGVVVKSIKEQLRSIPDRG 2968

Query: 1397 LDYGLLRYV--DGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGP--YLDALPIDP 1452
            + YGLLRY+  +   +L      QI F+YLGR+  GG  ++       P  +L  +    
Sbjct: 2969 IGYGLLRYLNHETAEQLRSLPVGQISFNYLGRVSGGGSPNEVPGAEWAPCGHLGDIAAPG 3028

Query: 1453 EPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
            + D+P    ++++  V   +EG  L   + +      R+++  L G W   +AALA
Sbjct: 3029 DADMPANGVVDINAIVTDGSEGPVLGATFTFPTGAIGRTEVQDLAGEWCAALAALA 3084



 Score =  525 bits (1353), Expect = e-146
 Identities = 451/1415 (31%), Positives = 643/1415 (45%), Gaps = 106/1415 (7%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AA P + DV  L+PLQ GL     LA   VD+YSMQ V  + G VD   L  +AQA+LDR
Sbjct: 3115 AAYPAVTDVWPLTPLQSGLLFHALLAASSVDVYSMQVVFTLTGRVDATRLHAAAQAVLDR 3174

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWSE-------RVATPAEFDSIARSERRRPFDLS 115
            HPNLR AF       PVQ+V     +PW E         A P     +  +++ R FD++
Sbjct: 3175 HPNLRVAFVGGADGIPVQLVLDKLPVPWREVDLRDVDDAARPDALTRLLAADQARHFDMT 3234

Query: 116  RGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXX 175
              P +R  +++   E +  ++   HHIL+DGWS+ +  T+LLA+                
Sbjct: 3235 APPLIRFTLVTA-AEDRYELVVANHHILLDGWSMPLLMTDLLALYAAGDEASALPPARPY 3293

Query: 176  XXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQ---SKPGKTELLLPAADTAR 232
              Y+ W A+QD +A+   W   L GV  P ++A  A  G+   S+ G+    L    T  
Sbjct: 3294 RSYLEWRAEQDEAASRRAWAAALEGVDGPTLLA-PADPGREISSRAGEVAADLGEQRTRA 3352

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L + A R  +T+NT +  AW +++ R+T R D VFG+ VSGRP QL GVE+M+GLFIN V
Sbjct: 3353 LSELAARLDVTVNTVMQAAWGILMMRMTGRDDTVFGSTVSGRPPQLTGVESMIGLFINTV 3412

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHG-RGPLFDSLFVFENAPID 351
            PV       E +    T++ R+ + + D  YL L+EIQ+  G    LFD+L VFE+ P++
Sbjct: 3413 PVRVRADPDETITQLLTRMHREQADLLDHLYLGLTEIQQSAGTTDTLFDTLTVFESYPVE 3472

Query: 352  DA--IRPATTPDGAQFLPVEMESLTHYPL----TVVSHLRXXXXXXXXXXXXXXXPYLPA 405
             A     A   DG     V     THYPL    TV + +R               PY+ A
Sbjct: 3473 QATLTEQADALDGITLAGVNANDNTHYPLALKITVDTQIR---LSLTYLHDLFDEPYVQA 3529

Query: 406  AEIGERMLTVLRQLPDIGDGTPDDLDI--RTAAELKAHGLLAARSAPTFDTTVWEMFERQ 463
              +  R L +L  +         D+DI   T  +L          A T DT V  +F  Q
Sbjct: 3530 --LLHRYLRLLGAIIADAGSPVGDIDILDPTEKQLILEDWNHTDHATTTDTLV-SIFGAQ 3586

Query: 464  VQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXX 523
            V                 +YAE  AR  RLA  L   GVGPET+VAL + RS        
Sbjct: 3587 VARTPDAPAVVDGNRTL-SYAEFDARVNRLARHLITQGVGPETIVALRMRRSLDFVVGVY 3645

Query: 524  XXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQL-VGTAVPTLALD----DP 578
                    YLP+D   P+ R   I+  A P   +T     Q+ +   VP L LD     P
Sbjct: 3646 ATLTAGAAYLPIDPHHPAERAHFILAVAQPTCILTTTHDEQVDLPDPVPVLHLDTIDLSP 3705

Query: 579  AAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXX 638
             +   ++     AP    RP+ +AYV+FTSGSTG PKGV   ++A+++      E  +  
Sbjct: 3706 LSAAPVTDADRHAPL---RPQNTAYVMFTSGSTGRPKGVTVAHSAIVN------EAQWVA 3756

Query: 639  XXXXXXXXXXXXHAWSLSFDASWQPMVGLLD-GHEIHLFDAEEMRDADRLVEGIAIGQID 697
                        +A  ++FDAS   +   L  G  + L   +  RD D L E I    I 
Sbjct: 3757 FDYGLGDRLLQSNA--VTFDASTPDLFAPLQVGGCVVLAGPDGQRDPDYLAELIRTQAIT 3814

Query: 698  MIDTTPSMFVQLSAAGLLD--HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMT 755
             + + P++   L A+   D    + V+ LGGE+++     +L       V+N YGPTE T
Sbjct: 3815 HMSSVPTVLTALMASRSPDVLRGVRVVYLGGESLSGNTVARLAEFGPATVWNQYGPTETT 3874

Query: 756  VEXXXXXXKDYRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRP 813
            V         + +    IGT       YV D  L  VP  VVGELY++G QLARGY  RP
Sbjct: 3875 VSVICHRCTQHEESVVPIGTPQTNCHAYVLDHRLHPVPVAVVGELYVAGVQLARGYHNRP 3934

Query: 814  GMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
             +TA RFVA+P   PG+RMYRTGDLVR    G   Y+GR D QVK+RG+R+E+GEIEA L
Sbjct: 3935 ALTAERFVANPYGPPGERMYRTGDLVRWHPDGTLEYLGRRDLQVKLRGHRIELGEIEATL 3994

Query: 873  RGQPGVHDAAVSVLRQQDR-TSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTL 931
               P +  AAV+V         LVG+VV +D    D  ++RA + +RLP YMVP+ I  L
Sbjct: 3995 TTHPDITHAAVTVHHDHHTGDRLVGYVVPRDGARLDPARVRALVADRLPDYMVPSPITVL 4054

Query: 932  PRLPVNANGKLDGHALDRLA-----EDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP 986
             RLP+ A+GK+D  AL           A  +V+ G       D       L  E++    
Sbjct: 4055 DRLPLTASGKVDRRALPAPVFPVPQYRAPVTVAEGVVAGVFADV------LDRERVG--- 4105

Query: 987  HIDDDLFLFGMDSIVAISLVHK-ARRQGLRVDPRMVLTATTIRQLGAAID--AAVDSQDA 1043
             +DDD F  G +S++A  +V +       RV  R++  A++++ L   ++  AA  +   
Sbjct: 4106 -LDDDFFTLGGNSLLATQVVSRLGAAMDARVPMRVLFEASSVQALSTWLESRAAAGAHTP 4164

Query: 1044 PADADYGAVRPLPMVS---WLYEYGNYRRFTHTV--LLRLPSGIDRSSIELMLQLLLDGH 1098
                      PL       W     +     + +   +RL   +D +++   +  ++D H
Sbjct: 4165 LVPRTRPEHIPLSYAQQRIWFLNRFDPHSPVYNIPFAVRLSGPLDTAALLAAIADVVDRH 4224

Query: 1099 DTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDP 1158
            +TLR+I  E+  GP  V    A V        +T     ++ELA+ +   A   + + D 
Sbjct: 4225 ETLRTIYPESEAGPHQVVVPAAEVSGGFATAAVT-----ENELATRLLSMA---SSEFDV 4276

Query: 1159 SAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAG-TP-- 1215
            +    VRA  F   E+     ++L +  HH+  D  S   +  DL AA+ +   G TP  
Sbjct: 4277 TTSVPVRAALFETAENE----HVLAVVLHHICADGSSIAPLARDLMAAYTARTGGHTPSW 4332

Query: 1216 PKILPEFTSYRRWCELMWHRASAPQ--VQDQRDYWAALVREPDPAL---GLRYPDPTRDT 1270
            P +  ++  Y  W   +      P   +  Q  YW + +      L   G R P      
Sbjct: 4333 PPLAAQYADYTLWQRELLGSDDDPNSLLARQLTYWRSTLDGQPEQLELPGNRTPPAVTHR 4392

Query: 1271 WSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVAL 1330
              T   T  A     T R    + R       ++  TA AV   R     D A G  VA 
Sbjct: 4393 GRTHTFTLDA----PTHRAAAELARQHTATVFMVLHTAFAVFLARTSGTGDIAIGTPVA- 4447

Query: 1331 EGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAA 1365
               GR D  LD    + VG F N   +R     A+
Sbjct: 4448 ---GRGDPALD----DLVGMFVNTLVLRTPVDGAS 4475



 Score =  482 bits (1240), Expect = e-133
 Identities = 450/1566 (28%), Positives = 671/1566 (42%), Gaps = 124/1566 (7%)

Query: 14   LSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDR 73
            LS  Q+G++   QLA + + +   Q+V ++ G +D++LL  +++       +      D 
Sbjct: 14   LSAAQKGIWFAQQLAGE-LPITIAQYV-EVFGELDIDLLEATSRVAAREFGSGFLRLVDH 71

Query: 74   DVPKPVQIVPVHAALPWSERVATPAEFD-SIA-----RSERRRPFDLSRGPALRVVVLSV 127
            D  +  Q+V   ++     R+   AE D S+A     R E   P DL    AL V  +  
Sbjct: 72   D-GELYQLVD-DSSDSGIRRIDFRAEDDPSVAAQQWMRREFSTPIDLLHD-ALAVSAILR 128

Query: 128  PGETKRRMIFTAHHILVDGW---SLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAK 184
             G+         HHI +DG+   +L     EL                       +  A 
Sbjct: 129  VGDRHYYWYSRIHHIALDGYGAMTLMQRIAELYTAAGAGVEAPPLHVLDLAQIVEIDAAY 188

Query: 185  QDRSAALAG---WMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRHG 241
            ++     A    W +   G+ EP  +A  +   ++ P      L     + L     +H 
Sbjct: 189  RNSDRFEADRRYWAERTSGLPEPASLAGRSAPVEAHPRVASAALSPDVASMLDSVVSKHN 248

Query: 242  LTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGT 301
             +    ++ A A  L R+T R D+V    VS R      +    G+  N VP+   V   
Sbjct: 249  SSAAPVLVAALAGFLCRMTGRSDIVLSLPVSARTTA--PLRRSGGMVANVVPLQLEVGAD 306

Query: 302  EAVVAQCTQVQRQSSAM----------------RDVSY-------LSLSEIQREHGRGPL 338
              + A     Q + +                  RD+S        L++    RE   GP 
Sbjct: 307  VTIGALIKSAQLELTGALRRQRYRREDICRDLGRDISRNRSFGPTLNIMPADREIRLGPH 366

Query: 339  FDSLFVFENAPIDDAIRPATTPDGAQFLPVEME---SLTHYPLTVVSHLRXXXXXXXXXX 395
               L V  +  +DD         G     ++ +   SL    +    H R          
Sbjct: 367  LGRLHVLTSGLVDDLFVNIYPSVGGTTTHIDFQANPSLYDDDVLDRHHHRLFLFLDRFL- 425

Query: 396  XXXXXPYLPAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTT 455
                     +A+ G R+                DLDI  A E +   LL     P    T
Sbjct: 426  ---------SADAGSRV---------------GDLDILDADERR--NLLDRTGGPEHPAT 459

Query: 456  VWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRS 515
                                      +Y +L   + +LA  L   G+G E  VA+ LPRS
Sbjct: 460  TLPQLLTTAAAHDRTAPAVIYRDHHLSYEQLDTASSQLARILIAEGIGTENTVAIALPRS 519

Query: 516  ERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLAL 575
              +             +LP+D   P  R+  ++  +  AL +T  +++  +   +P L +
Sbjct: 520  PDAILAVWATTKTGAAFLPIDPNYPKDRITHMLSDSRAALGLTTTEHATTLPGPLPWLVI 579

Query: 576  DDPAAVESISRRSAAAPTVDR---RP---EQSAYVIFTSGSTGEPKGVVGTNAAVLSYFA 629
            D P  +++        P  D    RP     +AY+++TSGSTG PKGVV T+  + +  A
Sbjct: 580  DTPD-IQTRCNTIDPGPITDTDRLRPLHTTNTAYLLYTSGSTGTPKGVVVTHQGLANLAA 638

Query: 630  DHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVE 689
            +  ER                   S SFDAS   ++         +     +   D L  
Sbjct: 639  EQHERFTTTPHSRTLAVA------SPSFDASVFELLLAAGTGATMVIAPPTVFGGDELTH 692

Query: 690  GIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGL---W----DQLRGLSQ 742
             +    I     TP+    +    L  H L  +   GEA    L   W    D     + 
Sbjct: 693  LLHTNHITHAVITPAALATIDPTHL--HTLHTVLSAGEACTPDLLTRWTTHTDTSPTHTP 750

Query: 743  MAVYNCYGPTEMTVEXXXXXXKDYRKP-TIGTANAGTFGYVFDSALRMVPDGVVGELYLS 801
               +N YGPTE TV            P TIG    GT  YV D  LR VP GV  EL+L+
Sbjct: 751  RRFFNGYGPTETTVMSNCSGPLPPGGPITIGGPIRGTHAYVLDDRLRPVPTGVTAELHLA 810

Query: 802  GAQLARGYVGRPGMTAARFVADPLRP-GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRG 860
            G QLARGY  RP +TA RFVA+P  P G+RMYRTGDLVR    G   ++GR D Q+K+RG
Sbjct: 811  GIQLARGYHNRPALTAERFVANPYGPPGERMYRTGDLVRWHPDGTLEFLGRRDLQIKLRG 870

Query: 861  YRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLP 920
            +R+E+ EIEA L   P +  AAV+V +      LV +VV       D  ++RA   +RLP
Sbjct: 871  HRIELAEIEATLTTHPDITHAAVTVHKGPVTEQLVAYVVPTPGAQIDPARVRAFAADRLP 930

Query: 921  SYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEE 980
             YM+P  I  L RLP+  NGK+D  AL   A                T TE+ + ++F +
Sbjct: 931  DYMLPDPITVLDRLPLTPNGKIDRRALPAPAP------LKPQFRPPVTPTEQTIADVFTD 984

Query: 981  --QLNAVPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAV 1038
              +L+ V  +D+  F  G DSIVAI LV +A+ +G+    R V    T+  L        
Sbjct: 985  VLELDRV-GVDESFFALGGDSIVAIQLVSRAKARGVVFSSRDVFERRTVSGLAEVAQRPE 1043

Query: 1039 DS--QDAPADADYGAVRPLPMV----SWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQ 1092
            DS    A  +   G +  +P+     + +   G + RF+  +L+ LP GI+R  +   ++
Sbjct: 1044 DSGLPVALEELPGGGIGWMPLTPVARALIERGGGFGRFSQHMLVELPPGIERGELVATIE 1103

Query: 1093 LLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHA-ARV 1151
             +LD HD  RS L     G  L      A+  + ++ R+ +    D+E A+A+A A    
Sbjct: 1104 AVLDHHDIFRSRLVGDERGWGLEVGGSDAIDVDGLVRRVEVTADLDEEAAAALASAQLDA 1163

Query: 1152 VTDQIDPSAGAMVRAIW--FRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRS 1209
               ++ P+ G MV+ +W  FR     A     LL+ AHHL +D VSW I+L DLA+AW  
Sbjct: 1164 ALGRLAPTTGVMVQFVWLDFRSECSTAQRPGRLLIVAHHLVIDGVSWRIILPDLASAWAQ 1223

Query: 1210 LQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRD 1269
            + AG  P + P  TS RRW   +   +SAP    +   W AL++ PDP LGLR  +   D
Sbjct: 1224 VSAGHTPVLDPAGTSMRRWSHALVEESSAPARLAELPMWQALLQAPDPVLGLRPFNAAID 1283

Query: 1270 TWSTLQLTRAAIPVDVTERVLGAVRR--DQGVRELLLAATAMAVASWRRVRAQDPAAGVL 1327
              STL     ++P      +L  +      GV + LLAA A+AV  WRR R Q   +  L
Sbjct: 1284 VGSTLDRVEVSVPAPAVASLLTTLPTLFHGGVEDGLLAALALAVCRWRRAR-QVSESSTL 1342

Query: 1328 VALEGHGRADAV-LDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVV 1386
            + LEGHGR + +    D + TVGWFT  FPVRL  GAA  D+++A     AA  +V S+ 
Sbjct: 1343 IQLEGHGRQEQIAAGADLSRTVGWFTTVFPVRLDIGAA--DLDEAFAGGAAAGVVVKSIK 1400

Query: 1387 SHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGP- 1443
              L +IP+ G+ YGLLRY+  +   +L      QI F+YLGR+  GG  ++       P 
Sbjct: 1401 EQLRSIPDRGIGYGLLRYLNHETAEQLRSLPVGQISFNYLGRVSGGGSPNEVPGAEWAPC 1460

Query: 1444 -YLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQR 1502
             +L  +    + D+P    ++++  V   +EG  L   + +      R+++  L G W  
Sbjct: 1461 GHLGDIAAPGDADMPANGVVDINAIVTDGSEGPVLGATFTFPTGAIGRTEVQDLAGEWCA 1520

Query: 1503 GIAALA 1508
             +AALA
Sbjct: 1521 ALAALA 1526



 Score =  326 bits (835), Expect = 2e-86
 Identities = 305/1075 (28%), Positives = 461/1075 (42%), Gaps = 76/1075 (7%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            + LS  Q+ ++ L++  +    +Y++ F V + GP+D   L  +   ++DRH  LR  + 
Sbjct: 4174 IPLSYAQQRIWFLNRF-DPHSPVYNIPFAVRLSGPLDTAALLAAIADVVDRHETLRTIYP 4232

Query: 72   DRDV-PKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSVPGE 130
            + +  P  V +     +  ++    T  E  +   S     FD++    +R  +     E
Sbjct: 4233 ESEAGPHQVVVPAAEVSGGFATAAVTENELATRLLSMASSEFDVTTSVPVRAALFET-AE 4291

Query: 131  TKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAKQ----- 185
             +  +    HHI  DG S+A    +L+A                   Y  +   Q     
Sbjct: 4292 NEHVLAVVLHHICADGSSIAPLARDLMAAYTARTGGHTPSWPPLAAQYADYTLWQRELLG 4351

Query: 186  ---DRSAALAGWMDYLRGVSEPLMVAYEATAGQSKP-----GKTELLLPAADTARLR-QW 236
               D ++ LA  + Y R   +      E    ++ P     G+T      A T R   + 
Sbjct: 4352 SDDDPNSLLARQLTYWRSTLDGQPEQLELPGNRTPPAVTHRGRTHTFTLDAPTHRAAAEL 4411

Query: 237  AGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVH 296
            A +H  T+   +  A+AV L+R +   D+  GT V+GR D  P ++ +VG+F+N + +  
Sbjct: 4412 ARQHTATVFMVLHTAFAVFLARTSGTGDIAIGTPVAGRGD--PALDDLVGMFVNTLVLRT 4469

Query: 297  YVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEI------QREHGRGPLFDSLFVFENAPI 350
             V G  +     T V+    A  + + +    +       R   R PLF  + VF+N   
Sbjct: 4470 PVDGASSFTQLLTTVRETDLAAFEHADVPFERVVQALNPARSTARHPLFQVMLVFQNQE- 4528

Query: 351  DDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAE--- 407
                 P    +G   L   +E + H        L                  L  A+   
Sbjct: 4529 ----HPKLELEG---LTARVEDIDHTATQFDLTLMVSERIDRDGAARGLTAALTYAQDLF 4581

Query: 408  -------IGERMLTVLRQLPDIGDGTPDDLDIR--TAAELKAHGLLAARSAPTFDTTVWE 458
                     +R   +L  +    +    D+DI   T  +L          A T DT V  
Sbjct: 4582 DEDTIRGFADRFTRLLEAVVADPNSPVGDIDILDPTEKQLILEDWNHTDHATTTDTLV-S 4640

Query: 459  MFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS 518
            +F  QV                 +YAE  AR  RLA  L   GVGPET+VAL + RS   
Sbjct: 4641 IFGAQVARTPDAPAVVDGNRTL-SYAEFDARVNRLARHLITQGVGPETIVALRMRRSLDF 4699

Query: 519  XXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQL-VGTAVPTLALD- 576
                         YLP+D   P+ R   I+  A P   +T     Q+ +   VP L LD 
Sbjct: 4700 VVGVYATLTAGAAYLPIDPHHPAERTHFILAVAQPTCILTTTHDEQVDLPDPVPVLHLDT 4759

Query: 577  ---DPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAE 633
                P +   ++     AP    RP+ +AYV+FTSGSTG PKGV   ++A+++      E
Sbjct: 4760 IDLSPLSAAPVTDADRHAPL---RPQNTAYVMFTSGSTGRPKGVTVAHSAIVN------E 4810

Query: 634  RVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLD-GHEIHLFDAEEMRDADRLVEGIA 692
              +               + +++FDAS   +   L  G  + L   +  RD D L E I 
Sbjct: 4811 AQWVVEAFDHRAGDRLLQSNAVTFDASTPDLFAPLQVGGCVVLAGPDGQRDPDYLAELIR 4870

Query: 693  IGQIDMIDTTPSMFVQLSAAGLLD--HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYG 750
              ++  + + P++   L A+   D    L V+ LGGE+++     +L   S   V+N YG
Sbjct: 4871 AQKVTHVASVPTVLTSLMASRSSDALDGLKVVYLGGESLSGNTVARLAEFSPATVWNQYG 4930

Query: 751  PTEMTVEXXXXXXKDYRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARG 808
            PTE TV         + +    IGT       YV D  L  VP  VVGELY++G QLARG
Sbjct: 4931 PTETTVSVICHRCTQHEESVVPIGTPQTNCHAYVLDHRLHPVPVAVVGELYVAGVQLARG 4990

Query: 809  YVGRPGMTAARFVADPLRP-GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGE 867
            Y  RP +TA RFVA+P  P G+RMYRTGDLVR    G   Y+GR D QVK+RG+R+E+GE
Sbjct: 4991 YHNRPALTAERFVANPYGPPGERMYRTGDLVRWHPDGTLEYLGRRDLQVKLRGHRIELGE 5050

Query: 868  IEAALRGQPGVHDAAVSVLRQQDR-TSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPA 926
            IEA L   P +  AAV+V         LVG+V  ++    D   +     +RLP YMVP 
Sbjct: 5051 IEATLTTHPDITHAAVTVHHDHHTGDRLVGYVAPRNGAPLDPTTIHTFAADRLPDYMVPT 5110

Query: 927  RIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP 986
             I  L  LP+  NGK+D  A   L    L +      V+A    E V+  +F + L    
Sbjct: 5111 PITILDALPLTTNGKIDRQA---LPTPVLPTPQYRAPVTA---VEGVVAWVFADVLGRDR 5164

Query: 987  -HIDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAIDAAVD 1039
              +DDD F  G +S++A   V + R   G+ +    + T +T+  + + ++AA D
Sbjct: 5165 IGLDDDFFTLGGNSLLATQAVSRLREALGVEIQVMWLFTDSTVEAIASRVEAASD 5219


>tr|Q8KLL5|Q8KLL5_STRTO Tax_Id=55952 SubName: Full=StaC;[Streptomyces
            toyocaensis]
          Length = 4066

 Score =  680 bits (1755), Expect = 0.0
 Identities = 533/1537 (34%), Positives = 744/1537 (48%), Gaps = 101/1537 (6%)

Query: 4    AAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRH 63
            A  +IED+  LSPLQEGL       ++G  +Y   +++++DGPVD   LR + + +L RH
Sbjct: 2    AQSRIEDIWPLSPLQEGLLFHTVYDDEGPHVYLGHWILELDGPVDPARLRTAWETLLTRH 61

Query: 64   PNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDS-------IARSERRRPFDLSR 116
              LRA F  R   + VQ+V     LPW  RV   +  D        +A  +R R FDL++
Sbjct: 62   AALRACFRQRATGETVQVVASGVDLPW--RVVDLSHLDDPDEAVRELAEEDRLRRFDLAK 119

Query: 117  GPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXX 176
             P LR+ ++ +   T  R++ T HH ++DGWSL + F EL A+                 
Sbjct: 120  APLLRLTLIRLDDAT-HRLVVTCHHAVMDGWSLPIVFDELQALYAAGTGSPDLPEVASYR 178

Query: 177  XYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELL---LPAADTARL 233
             Y+ WL +QD+  ALA W   LRG  +P +VA  A  G++ PG  E +   +P   T  L
Sbjct: 179  DYLAWLNRQDQKRALAAWAAELRGAQDPTLVA-PADPGRA-PGMPESITVEVPEHLTRSL 236

Query: 234  RQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVP 293
               A  +GLTLNT V  AWA+VL++L+ R DVVFG VVS RP  LPGVE MVGLF+N VP
Sbjct: 237  EDLARSNGLTLNTVVQGAWALVLAQLSGRTDVVFGAVVSARPADLPGVEGMVGLFLNTVP 296

Query: 294  VVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDA 353
            V   + G   V+   T++QR+ SA+    Y+ L EIQ+  G G +FD+L VFEN P    
Sbjct: 297  VRVRLDGATPVIGMLTELQRRQSALIPDQYVGLVEIQKAAGPGAIFDTLLVFENFP---- 352

Query: 354  IRPATTPDGAQFLPVEMES---LTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGE 410
             R    PD  +   V +       HYPLT+V+ +                    A  + E
Sbjct: 353  -RDLGEPDSPETFTVRVNQGREAAHYPLTLVA-VPGDTMLLKLDHLTDLFDADAALSVIE 410

Query: 411  RMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXX 470
            R   VLR L    + T  DL + TAAE                     +F+RQ +     
Sbjct: 411  RFQGVLRHLAADHETTVADLAVTTAAERNLVSAWGTAPGAEPGDLPLVLFDRQAERRGDE 470

Query: 471  XXXXXXXGVRHT-YAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXX 529
                   G R T + +L   A RLAG L   GVG    VA+V+ RS              
Sbjct: 471  TAIVD--GDRTTSFRDLAGYADRLAGYLTGRGVGRGDRVAVVMERSTDLIATLLAVWKAG 528

Query: 530  XXYLPVDVTLPSARVESIVRQASPALAITEA-DYSQLVGTAVPTLALDDPAAVESISRRS 588
              ++PVD   P  RV+ ++  A PA+ +  A + + ++   +  + LDDP    +++   
Sbjct: 529  AAFVPVDPGYPVERVKVMLADADPAVVVCRAANRAAVLDGGLDPIVLDDPEIRRAVAE-- 586

Query: 589  AAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXX 648
             A P+V    +  AYV++TSGSTG PKGV  ++  V +   +    +             
Sbjct: 587  CARPSVQVSADDLAYVMYTSGSTGTPKGVAVSHGNVAALVGEPRWEI----GPGDTVLTH 642

Query: 649  XXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQ 708
              HA+ +S    W P   LL G  + + +   + D + L   +A G +     T   F  
Sbjct: 643  ASHAFDISLFEIWVP---LLSGARMMIAEPGAV-DGEALARYVAAG-VTAAHLTAGAFRV 697

Query: 709  L------SAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXX 762
            L      S AGL +    VL  G E     +    R    + V + YGPTE T+      
Sbjct: 698  LAEESPESVAGLRE----VLTGGDEVPPAAVRRVRRACPDIRVRHLYGPTETTLCATWWL 753

Query: 763  XKDYRKP----TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAA 818
             +   +      IG   AG   +V D+ LR VP GV GELY++GA +ARGY+GR  +TA 
Sbjct: 754  LEPGDEAGGVLPIGRPLAGRRVHVLDAFLRPVPPGVKGELYVAGAGVARGYLGRSALTAE 813

Query: 819  RFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGV 878
            RFVADP  PG+RMYRTGDL      G   + GRAD QVKIRGYRVE GEIEA L G PGV
Sbjct: 814  RFVADPFVPGERMYRTGDLAHWTDEGTLVFGGRADDQVKIRGYRVEPGEIEAVLAGLPGV 873

Query: 879  HDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNA 938
              A   VL + +R  L+G+VV ++    D   LR  L E +P +MVPA ++ L  LP+  
Sbjct: 874  GQAV--VLARDER--LIGYVVAEEGRDLDPAGLRERLAETMPEFMVPAAVIVLDELPLTV 929

Query: 939  NGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV-PHIDDDLFLFGM 997
            NGK+D  A   L +    S S G     +T+ ER+LC +F E L      ++   F  G 
Sbjct: 930  NGKVDRQA---LPDPDFASKSVGR--DPATEVERILCRVFAEVLGLERVGVEAGFFELGG 984

Query: 998  DSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPM 1057
            DSI ++ +  +ARR+G+ + PR V    T  +L A +     S    ADA  G +   P+
Sbjct: 985  DSISSMQVAARARREGIALTPRQVFEQRTPERL-ARVAGTTRSGRFEADAGIGEIPWTPV 1043

Query: 1058 VSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTR 1117
            +  L        F    ++  P G+DRS++   LQ +LD HD LR          RL+  
Sbjct: 1044 MRALGADAQRPGFAQARVVVAPPGLDRSALVAALQAVLDTHDQLRG---RVESDGRLIVP 1100

Query: 1118 EPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRAD 1177
                V A  ++TR+     + DE+A   A  A  V   +DPS G MVR +W    +  A+
Sbjct: 1101 GRGTVDAAGLVTRVAAATANLDEIAGREAGTAAGV---LDPSTGTMVRVVWIDAGD--AE 1155

Query: 1178 PANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRAS 1237
            P   L L AHHL VD VSW I+L DL  A+  + +G    + P  TS+R+W   +  +A 
Sbjct: 1156 PGR-LALVAHHLVVDAVSWGILLPDLRTAYEQVISGGTASLEPATTSFRQWARRLTEQAL 1214

Query: 1238 APQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQ 1297
            + +   + D+W  ++   DP        P   +W TL  + A     +  +  GA     
Sbjct: 1215 SERTVAEIDHWVGVLDGADPFPEEHAGRPHSWSW-TLSGSAAR---SLVGQAPGAFH--C 1268

Query: 1298 GVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPV 1357
            GV+E+LLA  A AVA   R+R  D  AGVLV LEGHGR  A    D   TVGWFT+  PV
Sbjct: 1269 GVQEVLLAGLAGAVA---RLRGGD--AGVLVDLEGHGR-HAADGEDLLRTVGWFTSVHPV 1322

Query: 1358 RLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAV 1415
            RL    + +D+  A     AA +L+ +V   + A+P DG  YGLLR++  D  A L +  
Sbjct: 1323 RL--EVSGLDLAAAAAGNAAAGELLKAVKEQVRAVPGDGFGYGLLRHLNPDTGARLAELP 1380

Query: 1416 DPQIQFSYLGRLDLGGVADQPWSLLTGPY---LDALPIDPEPDLPLRFALNLSVFVGVTA 1472
             P+I F+YLGR       D PW ++ GP     DA      PDL L  AL +   V  T 
Sbjct: 1381 SPRIGFNYLGR-SAAASPDTPWQVVEGPLGAGADA------PDLVLAHALEVGARVQDTP 1433

Query: 1473 EGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
             G Q+       D   +   ++ L   W   +  LAA
Sbjct: 1434 GGPQVRLTVDGRD--LDPDTVERLGEAWLEMLTGLAA 1468



 Score =  625 bits (1611), Expect = e-176
 Identities = 514/1572 (32%), Positives = 734/1572 (46%), Gaps = 157/1572 (9%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AAAP + D+  LSPLQEG+     L E+GVD+Y  Q ++++DGP+D E LR + Q ++ R
Sbjct: 1498 AAAPGLTDIWPLSPLQEGMLFERALDEEGVDVYQSQRILELDGPLDPERLRAAWQPLVAR 1557

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWSER-VATPAEFDSIARSER------RRPFDLS 115
            H +LR +F      + VQ+V   A +PW E  V+   E D+ A  ER         FD++
Sbjct: 1558 HESLRTSFHQLGSGETVQVVVGEADIPWREADVSHLGEADAAAEVERLLAEDQAERFDVT 1617

Query: 116  RGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXX 175
            R P LR++++ + GE + R++ T+HH+L+DGWS  +   E+ +                 
Sbjct: 1618 RPPLLRLLLIRL-GENRHRLVLTSHHVLLDGWSTPIILGEMSS---GYAGGPGPSTSPSY 1673

Query: 176  XXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQ 235
              Y++WL++Q++ A L+ W     G  EP +V  +A      P +    L A  T  L  
Sbjct: 1674 RDYLLWLSRQEQDATLSAWRSEFAGSDEPTVVDADAGRAMVMPQEHCAWLSAESTRTLTD 1733

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
            +A  HGLTL+T V  AWA+VL+RL  R DV FGTVVSGRP  +P VE MVG+FIN VPV 
Sbjct: 1734 FARGHGLTLSTIVQGAWALVLARLAGRTDVAFGTVVSGRPADVPDVERMVGMFINTVPVR 1793

Query: 296  HYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIR 355
              + G   V+     +QR+ +A+ +  Y+ LSEIQ+  G G +FD++ + EN P+D A  
Sbjct: 1794 VRLDGGLRVLELLQDLQRRQAALTEHQYMGLSEIQKAVGPGAVFDTIMMVENYPLDAA-- 1851

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
                  G         + T YPLT+                        +A  GER+   
Sbjct: 1852 GLGDDGGVTISSAVTRTGTGYPLTM------------------------SASPGERLQIR 1887

Query: 416  LRQLPDIGDGTPDDLDIRTAAELKAH------------GLLAARSAPTFDTT-------- 455
            +          PD +D RTAAE+                L   R   T D T        
Sbjct: 1888 V-------SFRPDRIDERTAAEVAGQVVRVIERVAAEPSLPVGRLGVTSDATRTSEVERW 1940

Query: 456  -----------VWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGP 504
                       V E+F R+                  +Y +L   + RLAG LAE GV  
Sbjct: 1941 NATGEAAGGASVVELFRRRSAGTPDAVAVVDGDRTL-SYGDLDRESDRLAGRLAETGVRR 1999

Query: 505  ETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQ 564
               V +VL R                 Y+PV V  P  R+E ++  A   +A+       
Sbjct: 2000 GDHVGVVLERGADLFVAFLAVWKAGAAYVPVHVDYPPVRIERMLADAGVTVAVCAEGTRN 2059

Query: 565  LVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAV 624
             V   +  + +D P A E+        PTV  R   +AYV++TSGSTGEPKG+V  + +V
Sbjct: 2060 AVPDGLEPVPVDAPWAGETRHE----TPTVTAR--DAAYVMYTSGSTGEPKGIVVPHGSV 2113

Query: 625  LSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDA 684
             +   D    +               HA+  S    W P+V    G  + + +   + D 
Sbjct: 2114 AALAGDPGWAL----DADDCVLMHASHAFDASLFEIWAPLVR---GARVMVAEPGAV-DT 2165

Query: 685  DRLVEGIAIGQIDMIDTTPSMFVQLS--AAGLLDHNLSVLALGGEAINTGLWDQLR-GLS 741
             RL E +A G +  +  T   F  L+  + G  D  L  +  GG+ +      QLR    
Sbjct: 2166 QRLREAVARG-VTTVHLTAGSFRVLAEESPGSFD-GLREILTGGDVVPLASVAQLRRACP 2223

Query: 742  QMAVYNCYGPTEMTVEXXXXXXKDYRKP----TIGTANAGTFGYVFDSALRMVPDGVVGE 797
             + V + YGPTE T+       +   +P     IG   AG   YV D+ L+ V   V GE
Sbjct: 2224 DVRVRHLYGPTETTLCGTWHLLEPGDEPGDVLPIGRPLAGRRAYVLDAFLQPVAPNVTGE 2283

Query: 798  LYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVK 857
            LYL+G  LA GY+G  G T+ RFVADP  PG+RMYRTGDL RR   G   + GRAD QVK
Sbjct: 2284 LYLAGVGLALGYLGARGATSERFVADPFVPGERMYRTGDLARRNDRGELLFAGRADAQVK 2343

Query: 858  IRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQD---RTSLVGFVVWQDNMHEDLIKLRAG 914
            IRGYRVE  EIE  L   P V  A   V+ ++D      L+ + + + +   D   LR  
Sbjct: 2344 IRGYRVEPTEIETVLAEAPQV--AQTVVVAREDGPGEKRLIAYAIAEPDQVLDPEALREH 2401

Query: 915  LTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVL 974
            L  RLP +MVPA +V L   P+  NGK+D  AL   A +     +G       T+ ERVL
Sbjct: 2402 LAARLPEFMVPAAVVVLDDFPLTINGKIDREALP--APEFSAKPAGR---EPRTEAERVL 2456

Query: 975  CELFEEQLNA-VPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAA 1033
            C LF E L       DD  F  G DSI+++ L  +ARR  +    + V    T     AA
Sbjct: 2457 CALFAEILGLDRVGADDSFFELGGDSILSMQLAARARRADVVFGAKDVFEQET----PAA 2512

Query: 1034 IDAAVDSQDAP----ADADYGAVRPLPMVSWLYEYG----NYRRFTHTVLLRLPSGIDRS 1085
            I A  +   AP    AD D G V   P++  L E           T  V +  P  +   
Sbjct: 2513 IAAVAERGGAPRAELAD-DVGEVAWTPVMRALIERDPGALTGGALTQWVTVGAPGDLSVD 2571

Query: 1086 SIELMLQLLLDGHDTLRS-ILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASA 1144
            ++   L  ++  HD LRS I+T   E P +V    +AV A  ++ R+    G  DE+A  
Sbjct: 2572 ALAAGLGAVIGTHDLLRSRIVTAAGEEPGMVVSARSAVDAAGLVERVDADTGDIDEIAD- 2630

Query: 1145 VAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANI--LLLTAHHLAVDVVSWHIMLGD 1202
                AR    ++DP+AG M+RA+W       A P  +  ++L AHHL  D VSW I+L D
Sbjct: 2631 --RCAREAAARLDPAAGVMIRAVWV-----DAGPGRVGRIVLVAHHLVADAVSWQILLLD 2683

Query: 1203 LAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLR 1262
            L AA  ++ AG  P + P    +RRW   +  +A+      +   W  ++ + +P L   
Sbjct: 2684 LRAACEAVSAGAEPALDPVEVPFRRWARTLADQAAVRAA--ELGTWTEILDQAEPRLASL 2741

Query: 1263 YPDPTRDTWSTLQLTRAAIPVDVTERVLG--AVRRDQGVRELLLAATAMAVASWRRVRAQ 1320
              DP RDT +T       +P D    ++G  A     GV E+LLA  A AV  WR   A 
Sbjct: 2742 --DPARDTIATAGRRSWTLPRDRAGVLVGKAASAYHCGVHEVLLATLAGAVTRWRGGDA- 2798

Query: 1321 DPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQD 1380
                 V+V +EGHGR   V + D + TVGWFT+  PVRL      +D ++      AA  
Sbjct: 2799 -----VVVDVEGHGRR-PVGELDLSRTVGWFTDIHPVRL--DVTGIDTDEVIAGGEAAGR 2850

Query: 1381 LVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDP--QIQFSYLGRLDLGGVAD-QPW 1437
            L+ +V  ++  +P+ GL YG+LR+++     V A  P  +I F+YLGR       D +PW
Sbjct: 2851 LLKAVKENVRTVPDGGLGYGVLRHLNAETAPVLAALPKAEIGFNYLGRFSSRPEGDPEPW 2910

Query: 1438 SLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLT 1497
              +TG    A     E   PLR A+ +   V  + +G +L     W+  +   ++ + L 
Sbjct: 2911 Q-MTGTIGGA----AEEHAPLRHAVEVDAVVLDSPDGPELRLTLTWAGRILGEAEAESLG 2965

Query: 1498 GLWQRGIAALAA 1509
              W   ++ LAA
Sbjct: 2966 RAWLDLLSGLAA 2977



 Score =  451 bits (1161), Expect = e-124
 Identities = 357/1063 (33%), Positives = 508/1063 (47%), Gaps = 71/1063 (6%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            + AA P + D+  LSPLQEGL   H + E G D+Y+    + +DGP+D+   R S Q +L
Sbjct: 3004 IEAAVPGLADIWPLSPLQEGLL-FHAVDERGPDVYAGIRTLALDGPLDVARFRASWQTLL 3062

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSER-VATPAEFDSIARSERRRP------FD 113
            DRH  LRA+F      + VQ +     LPW+E  ++   E +++A +ER         F+
Sbjct: 3063 DRHAALRASFHQLGSGQAVQAIAGEVVLPWTETDLSHLPEDEALAEAERLAEELHADRFE 3122

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            L R P LR+ ++ +  E   R+   +HHI  DGWSL +   ++ A               
Sbjct: 3123 LDRAPLLRLHLMRI-SERSHRLALASHHISCDGWSLPILSGDVTAAYESGGDGRSLPAPT 3181

Query: 174  XXXXYIVWLAKQDRSAALAGWMDYLRGVSEPL-MVAYEATAGQSKPGKTELLLPAADTAR 232
                Y+ WLA+QD+ AA   W   L G+ EP  +V  +A     +P +    +    + R
Sbjct: 3182 SYRSYLAWLARQDKEAARQAWRSELAGLDEPTHVVPPDAVTAPVEPERLRFDMDEDLSRR 3241

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L ++  RHG+T+NT     WA++L+RLT R DVVFG+ V+GRP ++PGVE++VGLF+N +
Sbjct: 3242 LVEFTRRHGVTMNTLFQGIWALLLARLTGRDDVVFGSAVAGRPPEIPGVESVVGLFMNTL 3301

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDD 352
            PV   + G E  +   T++Q +  AM    ++ LSEI++  G+G  FD++ VFEN P   
Sbjct: 3302 PVRARLDGGEPFLDMLTRLQERQVAMMAHQHVGLSEIKQLAGQGAAFDTIVVFENYPRPP 3361

Query: 353  AIRPATTPDGAQFLPVEMESLT-HYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGER 411
               P+  PD     P  + + + HYP++    +R                        E 
Sbjct: 3362 L--PSEDPDALVMRPAGIPNDSGHYPIS----MRASHDGGVHGEFIYRPDVFDRTRAEEM 3415

Query: 412  MLTVLRQLPDIGDGTPDDLDIRTAA-ELKAHGLLA----ARSAPTFDTTVWEMFERQVQX 466
            +  V+R L  +    P  L  R         GL+     A  AP     +  +F R+ + 
Sbjct: 3416 LAAVVRALEQVA-ADPWTLVGRVGLIGPTERGLVVEEWNATDAPFVPEPLPVLFRRRAEL 3474

Query: 467  XXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXX 526
                         + +Y  L   A  LA  LA  GV  ET V +++ RS           
Sbjct: 3475 SRDAIAVEDADR-KLSYGGLLEEAEDLARLLAGLGVRRETRVGVLVGRSAELVVALLGVS 3533

Query: 527  XXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVP------TLALDDPAA 580
                 ++PVD   P+ R+E ++  ++P + +     ++   TAVP       + LD+ +A
Sbjct: 3534 LSGGVFVPVDPEYPAGRIELMLTDSAPEVLLC----TKATRTAVPDGFAGVVVVLDERSA 3589

Query: 581  VESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXX 640
             +      AA P V       AYVI+TSGSTG PKGV  T+A + +      ER      
Sbjct: 3590 ADP----GAALPAV--AVGDGAYVIYTSGSTGTPKGVQVTHAGLGNLAGAQIERFGVTSS 3643

Query: 641  XXXXXXXXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMI 699
                         SL FDA+   + + LL G  + L D + M     L + +   +I  +
Sbjct: 3644 SRVLQFA------SLGFDAAISELCMALLSGGTVVLADPDSMPPRVSLGDAVRRWRITHV 3697

Query: 700  DTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV--- 756
               PS+   L+    L  +L  L + GEA    L D+  G  +M   N YGPTE TV   
Sbjct: 3698 TVPPSV---LAVEEDLPDSLETLVVAGEACPPALVDRWSGDRRMI--NGYGPTETTVCVT 3752

Query: 757  -EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGM 815
                    +D   P IG   A    YV D+ L+ VP GV GELY++GA LARGY+GRPG+
Sbjct: 3753 MSAPLSPGRD--APPIGRPIANMRAYVLDAFLQPVPPGVAGELYVTGAGLARGYLGRPGL 3810

Query: 816  TAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQ 875
            TA RFVADP   G RMYRTGD  R    G   +VGRAD QVK+RGYRVE GEIEA L   
Sbjct: 3811 TAERFVADPFSSGGRMYRTGDRARWTREGELVFVGRADAQVKVRGYRVEPGEIEAVLSDH 3870

Query: 876  PGVHDAAVSVLRQQD---RTSLVGFVVWQDNMHED--LIKLRAGLTERLPSYMVPARIVT 930
            PG   A V ++ ++D      LV +VV       D  +  LR    ERLP +M P   V 
Sbjct: 3871 PGA--AQVVIVAREDGPGEKRLVAYVVPAAAQPADELIAALRETAAERLPEHMRPVAFVP 3928

Query: 931  LPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV-PHID 989
            L  +P+  NGK+D  AL   A D   + SG       T  E +LC +F E L      +D
Sbjct: 3929 LDAVPLTPNGKVDHRALQ--APDLAGNSSGR---GPRTAVEELLCAVFAEILGVERVGVD 3983

Query: 990  DDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGA 1032
            D  F  G DSI ++ L  + RR+GL V P  V    T  +L A
Sbjct: 3984 DSFFEIGGDSISSMQLSARLRREGLEVTPWQVFEEKTPERLAA 4026



 Score = 51.2 bits (121), Expect = 0.001
 Identities = 82/324 (25%), Positives = 127/324 (39%), Gaps = 24/324 (7%)

Query: 1076 LRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPE 1135
            L L   +D +      Q LLD H  LR+   +   G  +       V          LPE
Sbjct: 3043 LALDGPLDVARFRASWQTLLDRHAALRASFHQLGSGQAVQAIAGEVVLPWTETDLSHLPE 3102

Query: 1136 GSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVS 1195
              D+ LA A   A  +  D+ +     ++R    R +E     ++ L L +HH++ D  S
Sbjct: 3103 --DEALAEAERLAEELHADRFELDRAPLLRLHLMRISER----SHRLALASHHISCDGWS 3156

Query: 1196 WHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREP 1255
              I+ GD+ AA+ S   G   + LP  TSYR +  L W   +    +  R  W + +   
Sbjct: 3157 LPILSGDVTAAYES---GGDGRSLPAPTSYRSY--LAW--LARQDKEAARQAWRSELAGL 3209

Query: 1256 DPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWR 1315
            D    +  PD         +L R  +  D++ R++   RR  GV    L     A+   R
Sbjct: 3210 DEPTHVVPPDAVTAPVEPERL-RFDMDEDLSRRLVEFTRR-HGVTMNTLFQGIWALLLAR 3267

Query: 1316 RVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPV--RLGAGAAAVD-IEQAE 1372
                 D   G  VA    GR   +   +  + VG F N  PV  RL  G   +D + + +
Sbjct: 3268 LTGRDDVVFGSAVA----GRPPEIPGVE--SVVGLFMNTLPVRARLDGGEPFLDMLTRLQ 3321

Query: 1373 RDPVAAQDLVHSVVSHLEAIPNDG 1396
               VA     H  +S ++ +   G
Sbjct: 3322 ERQVAMMAHQHVGLSEIKQLAGQG 3345


>tr|A8LAS3|A8LAS3_FRASN Tax_Id=298653 SubName: Full=Amino acid
            adenylation domain;[Frankia sp.]
          Length = 6999

 Score =  674 bits (1738), Expect = 0.0
 Identities = 556/1666 (33%), Positives = 755/1666 (45%), Gaps = 193/1666 (11%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGV---------DLYSMQFVVDIDGPVDLELLR 53
            A  P +  V  +SPLQ GL   H L  DG          D Y +QFVVD+ G +D   LR
Sbjct: 1085 ARYPDLTGVRPVSPLQAGL-VFHSLLGDGSGTVPGAAGSDAYILQFVVDLRGRLDPARLR 1143

Query: 54   RSAQAMLDRHPNLRAAF-WDRDVPKPVQIVPVHAAL---PWSE-------RVATPAEFDS 102
             + +A+ +RH NLR AF +D D P  + +  +  A     W+E       R    AE + 
Sbjct: 1144 AAGRALFERHENLRTAFLYDGDAPVQIVLADLAPAAFDEVWTEVDLAGWPRAEALAEAER 1203

Query: 103  IARSERRRPFDLSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELL----- 157
            + R++R+ PFDL+  P +R ++L   G    R++ + HH+++DGWS+ +   EL      
Sbjct: 1204 LGRADRQTPFDLTAPPLVRFLLLRT-GPDAWRLVLSPHHVVLDGWSVPLLLRELFRRYEL 1262

Query: 158  ----AVXXXXXXXXXXXXXXXXXXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATA 213
                +                   Y+ WLA +DR A+   W   L GV+EP ++A  ATA
Sbjct: 1263 AQSQSQAQADGPAAALPPAPSYWEYLRWLAGRDRDASRRAWAAALAGVTEPTLLA-AATA 1321

Query: 214  GQSKPGKTELLLP-------------------------------AADTARLRQWAGRHGL 242
                P +T    P                               AA TA L  +    GL
Sbjct: 1322 RPGTPAQTAAHAPDQVPEQAPDQAVDQWDTVDGGVTAAVERHADAALTAGLGTFVRERGL 1381

Query: 243  TLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTE 302
            TLNT +  AWAVVL R   R DVVFGT V+GRP +LPG   M+GL +  VPV   +   E
Sbjct: 1382 TLNTVLRAAWAVVLGRAVGRDDVVFGTSVAGRPAELPGAAEMIGLLLATVPVRVTLDPAE 1441

Query: 303  AVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPD- 361
            + V    +V+   +A  +  +L L++I    G   LFD+LFV E+ P D A      PD 
Sbjct: 1442 SFVGLLDRVRADQTATLEHHHLGLADIHAAVGLPELFDTLFVLESYPFDPA--GLLGPDS 1499

Query: 362  GAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQLPD 421
            G +   ++    THYPLT+                     Y P    G  +  +  QL D
Sbjct: 1500 GLRLEGLDGHDATHYPLTI--------RVIPGERLRITFGYRPELLSGATVTALADQLLD 1551

Query: 422  IGDGTPDDLDIRTAA------ELKAHGLLAARSAPT------------FDTTVWEMFERQ 463
            +      D D    A       +   G + A  A T             DTT+ E+FE Q
Sbjct: 1552 LLAAAIADPDKPVGAIGAPAGSVAPAGTVGAAPAATRPEEDEPTGAWATDTTLPELFEAQ 1611

Query: 464  VQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXX 523
                            R TYAEL A A RLA  LA  GV PE++VA+ LPRS        
Sbjct: 1612 AARVPDAVAVTWGER-RLTYAELDAAANRLARLLATRGVEPESLVAVALPRSIDLVVALL 1670

Query: 524  XXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVG--TAVPTLALDDPAAV 581
                    YLP+D   P+ R+  ++  A+P   +T A+    +   T VP +ALD P  V
Sbjct: 1671 AVQKAGAAYLPLDTAYPADRLAFMLSDAAPVCLVTSAEALPALPARTRVPMIALDAPPVV 1730

Query: 582  ESISRRSAAA-PTVDR-RPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXX 639
             +++ +S A  P   R RPE +AYVI+TSGSTG PKGVV  +  V   FA H +  +   
Sbjct: 1731 AALAEQSPARLPAAGRARPENAAYVIYTSGSTGRPKGVVVPHQTVTRLFA-HTQPWFGFD 1789

Query: 640  XXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDM 698
                          S SFD S W+    LL G  + + D    R  +  ++ +    + +
Sbjct: 1790 ETDVWTMFH-----SASFDFSVWELWGPLLYGGRLVVVDHHVSRSPELFLDLLRRESVTV 1844

Query: 699  IDTTPSMFVQLSAAGLLDHN------LSVLALGGEAINTG---LWDQLRGLSQMAVYNCY 749
            +  TPS F QL  A            L  +  GGEA++ G    W          + N Y
Sbjct: 1845 LSQTPSAFSQLIEADRAGGEDPAELALRYVVFGGEALDLGRLPAWYARHRDDAPVLVNMY 1904

Query: 750  GPTEMTVEXXXXXXKDY-----RKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQ 804
            G TE TV        +      R   +G    G   +V D  LR V  G +GELY+SG Q
Sbjct: 1905 GITETTVHVTYLRLDEAVVAAARASLVGGPIPGLRVHVLDQHLRPVAPGGLGELYVSGGQ 1964

Query: 805  LARGYVGRPGMTAARFVADPLR-PGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRV 863
            LARGY+GRPG+TA RFVADP   PG RMYRTGDL RR + GG+ Y+GRAD QVK+RG+R+
Sbjct: 1965 LARGYLGRPGLTATRFVADPFGGPGARMYRTGDLARRTADGGFEYLGRADDQVKVRGFRI 2024

Query: 864  EVGEIEAALRGQPGVHDAAVSVLRQQ-DRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSY 922
            E+GEI+AA+   P V  A V     Q  +  LVG+VV       D  +LR      LP +
Sbjct: 2025 ELGEIQAAIATHPAVEQAVVLAREDQPGQRRLVGYVVAAPGRRVDSEELRRHAAAMLPEF 2084

Query: 923  MVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQL 982
            MVP  ++ L   P+  NGKLD  AL   A D L SVS GT   A T+ ER LC +F   L
Sbjct: 2085 MVPVAVLALDAFPLTGNGKLDRAALP--APD-LASVSTGT--RARTERERTLCAVFAGVL 2139

Query: 983  NA-VPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGA----AIDAA 1037
                  +DDD F  G DSI AI LV++ARR+ +   PR V T  T  +L A    A  A 
Sbjct: 2140 GLDEVGVDDDFFTLGGDSISAIQLVNRARREQVGFTPRDVFTHRTPAKLAALTEPAASAV 2199

Query: 1038 VDSQDAPA-------------------DAD---YGAVRPLPMVSWLYEYGN-YRRFTHTV 1074
              + D PA                    AD    G   PLP+VS L  +G   RRF   +
Sbjct: 2200 STAPDGPAAFAGPGAAPDRPGGAGTGLGADPEAIGVFTPLPIVSRLASWGGPVRRFNQAM 2259

Query: 1075 LLRLPSGIDRSSIELMLQLLLDGHDTLRS-ILTETPEGPRLVTREPAAVRAEDVLTRITL 1133
            L+  P+G     +   +Q LLD HD LR+ +L  +P    L T    + RA D+L R+ +
Sbjct: 2260 LVSTPAGATVDLLRGAVQALLDQHDALRARLLRPSPALWLLETLPVGSARAGDLLRRVDI 2319

Query: 1134 PEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDV 1193
                +  L +AVA  +    D +DP AGAM+R  W    +  +D    LLL AHHL VD 
Sbjct: 2320 AGLDEAGLRAAVAAESAAAADGLDPEAGAMLRVSWL---DAGSDQPGRLLLVAHHLVVDG 2376

Query: 1194 VSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVR 1253
            VSW ++L DL  A+ ++ AG  P + P  TS R +  +   RA  P    +  +W A + 
Sbjct: 2377 VSWRVLLADLRTAFAAVLAGRAPHLDPVGTSLRAFARITAERAQDPARLAELAHWTATLA 2436

Query: 1254 EPDPALG----------------LRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQ 1297
                 LG                        DT +        +P   T  +L +V    
Sbjct: 2437 PGGRLLGGAPSTGAAAATGAAAAPGAAPAAADTIADTDRLVVELPARATAPLLTSVPAAA 2496

Query: 1298 G--VRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAF 1355
            G  V  +LLAA   AV  WRR R  D ++ +LV LE HGR     + D + TVGWFT   
Sbjct: 2497 GTDVTAVLLAALRAAVTGWRRERGWDGSSDLLVDLERHGRDPIAPEVDLSRTVGWFTAIS 2556

Query: 1356 PVRLGAGAAAVDIEQAERDPVAA-------QDLVHSVVSHLEAIPNDGLDYGLLRYVDGV 1408
            PVRL A       + A  DP +           + +V   L  IP+ G  +GLLRY +  
Sbjct: 2557 PVRLPASG-----DPASGDPASGGLASGGLAGTLEAVAGRLREIPDGGAGFGLLRYANAA 2611

Query: 1409 AE--LVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSV 1466
            A   L  A  P++ F+YLGR   G  A   W+    P LDAL  +P+P + + + L +  
Sbjct: 2612 AAPVLAGAEHPEVLFNYLGR--FGADAADAWA--PAPELDALAAEPDPAMGVAYPLTVDA 2667

Query: 1467 FVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD 1512
                T +G  L     +   V +R+    L   W   +  LA   D
Sbjct: 2668 VSVQTPDGPVLRTTLTYLTTVIDRTAAGALATAWLAALDGLAGLAD 2713



 Score =  448 bits (1153), Expect = e-123
 Identities = 340/980 (34%), Positives = 467/980 (47%), Gaps = 89/980 (9%)

Query: 8    IEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLR 67
            + ++  LSPLQEGLF  H   +   D Y+ QF +D     D++ LRR+ +  + R+P LR
Sbjct: 2766 VAEIWPLSPLQEGLF-FHSAFDRSSDAYTAQFALDFGHRFDVDRLRRACETFMRRNPTLR 2824

Query: 68   AAFWDRDVPKPVQIVPVHAALPWSERVAT--PA-----EFDSIARSERRRPFDLSRGPAL 120
            A F    +P P+Q V      P  E   T  PA     + + +AR +R RPFD+S  P  
Sbjct: 2825 AGFLGDGLPAPLQFVVTELPAPLEETDLTGLPAAERAEQAELLARRDRERPFDISNPPLW 2884

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX-YI 179
            R+ +L + G    R++F    ++ DGWS A+   +LL +                   ++
Sbjct: 2885 RLTLLRL-GPDHDRLVFNRQVLVWDGWSGALVIDQLLGLYERGGGDEGLPVPAASYRDFL 2943

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATA-GQSKPGKTELLLPAADTARLRQWAG 238
            VWL  +D + A   W   L  +  P +V  EA      +P +    L  +    +R+ + 
Sbjct: 2944 VWLRARDTAGAEEAWRAALADLDGPTLVVPEARGLPPIEPERITTELAESTARAVRELSR 3003

Query: 239  RHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYV 298
            RHG+T+NT    A A+VL       DVVFGT V+GRP  + G++ ++GLF+N VPV   +
Sbjct: 3004 RHGITVNTVFNAALALVLGNAVGSDDVVFGTTVAGRPTDVEGIDEVIGLFLNTVPVRVRL 3063

Query: 299  SGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPAT 358
               E+V+    +VQ Q   + D  YL L +IQR  GR  LFD+L+V +N  ID+    AT
Sbjct: 3064 DPRESVLDLLRRVQDQRVDVMDHEYLGLGDIQRASGRTQLFDTLYVLQNF-IDEV---AT 3119

Query: 359  TPDGAQFLPVEMESL--THYPLTVVSHLRXXXXXXXXXXXXXXXPYLP-------AAEIG 409
                 +F      S+  THYPLT V                    Y P       AA + 
Sbjct: 3120 EQSSDRFGITGGTSIDHTHYPLTFV--------LFPGTRITMRLEYRPDVVGAQRAAALF 3171

Query: 410  ERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTF----DTTVWEMFERQVQ 465
            +R   +L +L          +++   AE      LAAR A  F      TV +M   QV 
Sbjct: 3172 DRFRGLLDELVRDVTVPVGSVEVLLPAE---RAELAARWAEPFLPVGTETVADMLAAQVA 3228

Query: 466  XXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXX 525
                          R +YA+L AR   +A  L   G GPETVVAL L RS          
Sbjct: 3229 RTPDLTALVFGDE-RVSYADLDARVNWMARLLLARGAGPETVVALGLGRSVNMVVALFAV 3287

Query: 526  XXXXXXYLPVDVTLPSARVESIVRQASPALAI-TEADYSQLVGTA------VPTLALDDP 578
                  YLP+++  P AR+  +V  A  AL + T+A  + L G        VP L LDDP
Sbjct: 3288 LRTGAAYLPLELDHPPARLLGMVADAGAALLVATDATAAYLDGAGAGPDEPVPRLLLDDP 3347

Query: 579  AAVESISRRSA-----------AAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSY 627
            A    ++   A           A    DR  +  AYVI+TSGSTG PKGVV     + + 
Sbjct: 3348 AMAAELAATGAGELSDAELGLFARDRADRL-DHPAYVIYTSGSTGRPKGVVTPYRGLTNM 3406

Query: 628  FADHAERVYXXXXXXXXXXXXXX-HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADR 686
              +H E ++               H  S +FD SW+ ++ L++GHE+H+ D    RDA+ 
Sbjct: 3407 QLNHREEIFAPAVAAAGGRRLRIAHTVSFAFDMSWEELLWLVEGHEVHVCDENLRRDAEA 3466

Query: 687  LVEGIAIGQIDMIDTTPSMFVQLSAAGLLD------HNLSVLALGGEAINTGLWDQLRGL 740
            LV      Q+D+++ TP+    L   GLLD      H   ++ LGGEA++  +W++LR  
Sbjct: 3467 LVAYCDAHQVDVVNVTPTYAHHLFELGLLDRAEDGRHRPPLVMLGGEAVSEAVWNRLRDT 3526

Query: 741  SQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYL 800
            +  A YN YGPTE T+        D   PT+G     T  YV D  L  VPDGV GELY+
Sbjct: 3527 ADTAGYNLYGPTEYTINTLGAGTADSPTPTVGRPIRNTRAYVLDGWLHPVPDGVPGELYI 3586

Query: 801  SGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDL-VRRLSHGGYAYVGRADTQVKIR 859
            +G  LARGY+ R  +TA RFVADP  PG RMYRTGDL VR  + G   ++GR D QVKIR
Sbjct: 3587 AGDGLARGYLDRFALTATRFVADPRVPGGRMYRTGDLVVRGAADGNLDFLGRTDEQVKIR 3646

Query: 860  GYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERL 919
            GYRVE+GEI AAL   P V  AAV      D T   G                   T RL
Sbjct: 3647 GYRVELGEITAALDRHPRVSQAAVVA---ADDTGAPG-------------------TRRL 3684

Query: 920  PSYMVPARIVTLPRLPVNAN 939
             +Y+VPA +    R  V A+
Sbjct: 3685 VAYVVPAELTAADRAAVEAD 3704



 Score =  398 bits (1023), Expect = e-108
 Identities = 369/1152 (32%), Positives = 503/1152 (43%), Gaps = 158/1152 (13%)

Query: 479  VRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVT 538
            V  TYAEL ARA RLA  LA  G GPE+VVA+ +PRS                +LP+D+ 
Sbjct: 5879 VELTYAELDARANRLARLLAARGAGPESVVAVAVPRSADLVVALLGVLKTGAAFLPLDLD 5938

Query: 539  LPSARVESIVRQASPALAITEADYSQLV------------------------GTAVPTL- 573
             P+ RV  ++  A   L ++   +++ +                        GT  P L 
Sbjct: 5939 HPADRVAFMISDAGARLLVSTRGHAEELIALGALGALGALGVPGPLGDPGAPGTGAPGLD 5998

Query: 574  --ALDDPAAVESISRRSAAAPT--VDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFA 629
               LD+P     ++    A P   V    + +AYVI+TSGSTG PKGVV T+  V S  A
Sbjct: 5999 LVLLDEPGTAAELATGDPARPGTGVATSLDSAAYVIYTSGSTGRPKGVVVTHEGVGSLVA 6058

Query: 630  DHAERVYXXXXXXXXXXXXXXHAWSLSFD-ASWQPMVGLLDGHEIHLFDAEEMRDADRLV 688
               +R+                  S+ FD A +   + L  G    +  A+       L 
Sbjct: 6059 TAVDRLGVNGTSRVAQFA------SVGFDVAVFDLCMALCVGGRAIIVPAQRRVAGPELT 6112

Query: 689  EGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNC 748
              +A      +   P++   L A   L    +VL +G E +   +    R  S + V   
Sbjct: 6113 GYLADHGATHMILPPALVAALPADCALPAG-AVLVVGTETVP--IETVRRWSSHLRVVAA 6169

Query: 749  YGPTEMTVEXXXXXXK-DYRKPT-IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLA 806
            YG TE TV         D+     IG  +  T  YV D+ALR V  G VGELY+ G  LA
Sbjct: 6170 YGLTEATVNSTLWQADPDWTGAVPIGVPDPNTRAYVLDTALRPVGVGAVGELYIGGRGLA 6229

Query: 807  RGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEV 865
            RGY+GRP +TA RFVADP  RPG R+YRTGD  R    G   ++GRAD Q+KIRGYR+E 
Sbjct: 6230 RGYLGRPALTAQRFVADPFGRPGDRLYRTGDRARWRPGGVLDFLGRADDQIKIRGYRIEP 6289

Query: 866  GEIEAALRGQPGVHDAAVSVLRQQDR---TSLVGFVVWQDNMHE---------DLIKLRA 913
            GEI++ L   PGV  A   VL ++DR     LV +VV  D             D   LR 
Sbjct: 6290 GEIQSVLMRHPGVRQAV--VLAREDRPGSLQLVAYVVPVDPAQTGPAPGGGRLDPAALRV 6347

Query: 914  GLTERLPSYMVPARIVTLP-RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTER 972
               E LP YMVPA +V +P RLP+  NGKLD  AL   A     S +     SA   TE 
Sbjct: 6348 HAAEYLPEYMVPAAVVLVPGRLPMTPNGKLDRAALP--APRFALSAADRAPASA---TEA 6402

Query: 973  VLCELFEEQLN--------------------AVPHIDDDLFLFGMDSIVAISLVHKARRQ 1012
             LCELF E L                     A   +DDD F  G DSI+++ LV + R  
Sbjct: 6403 RLCELFAELLGLGDSRRGPAAEEQAGRQPAAAAVGVDDDFFALGGDSIISMRLVSRLRAD 6462

Query: 1013 GLRVDPRMVLTATTIRQLGAAIDAAVDSQ----------------DAPADADYGAVRPL- 1055
            G  V P  V    T  +L A +  A                     A A    G V P  
Sbjct: 6463 GFVVRPAQVFRHRTPAELAAVLTGAGALSGTVATTGAGPLPGAVATAVASDGVGVVPPTP 6522

Query: 1056 PMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTE-----TPE 1110
            P+++     G    F+  +LL +P+ +   ++  +L  + + H+ LR+ L        P+
Sbjct: 6523 PLLALRAAGGGVDGFSSPMLLHVPASVTLPALRAVLAAVAERHEILRARLVRAATGTVPD 6582

Query: 1111 GPRLVTRE-----------PAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPS 1159
            G    + +           P        + R+ +  G+DD+L   +A  A     ++DP 
Sbjct: 6583 GLPATSADGGEAWYLDVPPPGPAGVGSWVRRVEV--GADDDLDRMLAAEALRANRELDPD 6640

Query: 1160 AGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKIL 1219
            AGAMVR +WF         +  LL+  HHL  D VSW I+L DLAAAW +L  G  P + 
Sbjct: 6641 AGAMVRVVWFDAGHSN---SGRLLVLVHHLVTDGVSWQIILDDLAAAWNALTRGGVPALA 6697

Query: 1220 PEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPD-----PTRDTWSTL 1274
            P  TSYRRW   +  +A  P+ + +  YW   V    P      P+     P  DT + +
Sbjct: 6698 PVSTSYRRWALGVTEQARRPEREAELAYWLRTVEGGAPLPRPEIPEVERAAPEHDT-AVV 6756

Query: 1275 QLTRAAIPVDVTER------VLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLV 1328
            +    A+   + E       V+       G  E+LLAA A+AVA  RR      AAG++V
Sbjct: 6757 ERDAGAVTATIPETWAGDVLVVAPAAWGVGADEILLAALALAVADCRRRWEGTQAAGLVV 6816

Query: 1329 ALEGHGRADAVLD-TDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVS 1387
            AL+ HGR D  +D  D T TVGWF +  P+ L      VD+     DP A   L  +VV+
Sbjct: 6817 ALQSHGRVDPEVDEADLTRTVGWFADVHPLCL--DQRPVDL----GDPAAGAALDAAVVA 6870

Query: 1388 ---HLEAIPNDGLDYGLLRYVD--GVAELVDAVDPQIQFSYLGRLDLGGVAD-----QPW 1437
                    P  G  YGLLR+++      L  A  P +  +Y GR      AD     +  
Sbjct: 6871 VHRRKAETPRGGSGYGLLRHLNPRTAPVLARAGQPAVYLNYEGRWSRPEPADWDVAREDE 6930

Query: 1438 SLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLT 1497
             L  G   ++   DP P   +  AL+L         G +L+  W         S +  L 
Sbjct: 6931 GLFAG--WNSERADPFPLTVIIRALDL-------PGGLRLVARWTSGAGGLPASAVGDLA 6981

Query: 1498 GLWQRGIAALAA 1509
              W R +AALAA
Sbjct: 6982 TAWTRALAALAA 6993



 Score =  355 bits (912), Expect = 2e-95
 Identities = 307/947 (32%), Positives = 425/947 (44%), Gaps = 103/947 (10%)

Query: 478  GVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDV 537
            G + T+AEL  +   LA  LA  G G E VVAL LPR+ R              YLP+D 
Sbjct: 4777 GTKLTFAELAEQVGSLAWLLARRGAGIEDVVALALPRA-RMVPALLGVMTAGACYLPIDT 4835

Query: 538  TLPSARVESIVRQASPALAITEADYS-QLVGTAVPTLALDDPAAVESISRRSAAAPTVDR 596
              P+ R+  ++  A P L +T A  + QL  T    + LDDPA    ++   A  P    
Sbjct: 4836 DHPADRLAFLLTDARPRLVLTTAALAGQLPATGAEVVVLDDPAVQAELAAHPAGLPIAGL 4895

Query: 597  RP-------EQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXX 649
             P       + +AYVI+TSG+TG PK VV T+  V + FA H   +              
Sbjct: 4896 PPAGQALRGDNAAYVIYTSGTTGRPKAVVATHRGVTNLFASHEVELILPAVAAWGGDGPL 4955

Query: 650  X--HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFV 707
               HA S SFD SW+P++ L  GH +H+ D   MRD   L E +   +ID +D TP+   
Sbjct: 4956 RAVHAASFSFDGSWEPLLWLFAGHTVHVADEATMRDPAALAEYVVNARIDFLDVTPTYLR 5015

Query: 708  QLSAAGLLD--HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKD 765
            +L   G LD  H   V+A+GGEA    LW++LR L  +  ++ YGPTE +V+        
Sbjct: 5016 ELVHLGFLDGAHLPGVIAVGGEATPAPLWERLRTLPGVVAHDLYGPTEYSVDAYGWHGDG 5075

Query: 766  YRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL 825
               P      A T   V D+ L  VPDGV GELYL+G  LARGY+GRPG++A RFVADP 
Sbjct: 5076 TAGPV-----ANTRALVLDAGLEPVPDGVPGELYLAGDGLARGYLGRPGLSATRFVADPF 5130

Query: 826  -RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVS 884
              PG RMYRTGD  RR + G  A++GR D QVK+RG+R+E GEIEAAL   PGV  AA +
Sbjct: 5131 GAPGGRMYRTGDRARRRADGTLAFLGRVDDQVKVRGFRIEPGEIEAALLALPGV--AAAA 5188

Query: 885  VLRQQDRTS---LVGFVV--------------------------WQDNMHEDLIKLRAGL 915
            V+ ++D      LV +VV                            D    DL  LR+ L
Sbjct: 5189 VIVREDAAGDPRLVAYVVPDGPCATADPGVAVPGPADPAAADRATGDRAVADLGALRSEL 5248

Query: 916  TERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLC 975
               LPS++VP+  V +  LP   +GKLD  AL    E A  +  G     A    E +L 
Sbjct: 5249 ARTLPSHLVPSAFVAVAELPRTVSGKLDRAALPAPGEPA--AWPGRRPRGA---REELLA 5303

Query: 976  ELFEEQLNAVPHI-------DDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTI 1027
            E F   L     +       +DD F  G  S++A+ L  + R   G+ V  R +    T+
Sbjct: 5304 EQFAAVLGTAEVLGTAEIGAEDDFFALGGHSLLAMRLRSRIRSVFGVEVSARDIFDEPTV 5363

Query: 1028 RQLGAAIDAAV-DSQDAPADADYGAVRPLPMVS---WLYEY--GNYRRFTHTVLLRLPSG 1081
              L   +D AV  ++ A A AD     PL       W+     G    +   V  RL   
Sbjct: 5364 AGLARRLDGAVAAARPALAPADRPQRPPLSHAQARLWVLGQVEGPSPTYNIPVTWRLEGP 5423

Query: 1082 IDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDEL 1141
            +D  ++   +  ++  H+ LR++       P     +PAA R +  L  +    GS  +L
Sbjct: 5424 LDVGALRAAVGDVVTRHEALRTVFPAPDGVPHQRVLDPAAARVDVELIEL----GSAGDL 5479

Query: 1142 ASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADP-ANILLLTAHHLAVDVVSWHIML 1200
            A  + +A+  V D        + R +  R T  R DP  +++    HH+A D  S   + 
Sbjct: 5480 ARRLENASARVFD--------LERELPVRVTAVRLDPRLHVVQFLVHHIAADEGSDQALA 5531

Query: 1201 GDLAAAWRSLQAGTPPKILP---EFTSYRRWCELMWHRASAP--QVQDQRDYW----AAL 1251
             DL+ A+R+   G  P+  P   ++  Y  W   +    S P      QRD+W    A L
Sbjct: 5532 RDLSTAYRARLRGEAPRWAPLPVQYVDYTLWQRALLGDESDPASPASAQRDFWRRELAGL 5591

Query: 1252 VREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAV 1311
              E         P         ++LT  A  +D     L A  R   V   ++    +A 
Sbjct: 5592 PVELAVPTDRSRPAEPSHRGGVVELTWDAELLD----RLRATARAHDVSLFMVLQALVAT 5647

Query: 1312 ASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
               R     D   G  VA    GR D  LD    + VG+F N   +R
Sbjct: 5648 LLHRLGAGDDIPIGSPVA----GRGDERLD----DLVGFFLNTLVLR 5686



 Score =  338 bits (866), Expect = 5e-90
 Identities = 407/1451 (28%), Positives = 583/1451 (40%), Gaps = 209/1451 (14%)

Query: 35   YSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWS--- 91
            Y++    D+ GPVD + L  + +A+   H  LR  +      +P Q+V       WS   
Sbjct: 14   YNVAASFDLTGPVDADALHAALRAVARGHEILRTTYRVPAGGRPEQVVHAELDPQWSSHD 73

Query: 92   ---------ERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSVPGETKRRMIFTAHHI 142
                     ER+A     D IAR   RRPFDL+    LRV ++ +  + +  ++  AHH+
Sbjct: 74   VSGEPSASRERLA-----DEIARHAARRPFDLTSSSPLRVTLIRLAAD-RFVLVVVAHHV 127

Query: 143  LVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAKQDRSA--------ALAGW 194
              D  S  +FF EL A                     + +A Q R A        AL  W
Sbjct: 128  AWDDASWEIFFRELFAHYDNLRAGDGPLPADERTAQYIDVAGQPRGADAQDPDPAALDYW 187

Query: 195  MDYLRGVSEPLMV-----AYEATAGQSKPGKT----------ELLLPAADTA-------- 231
               L  + EPL +        ATA  + PGK           +L  P             
Sbjct: 188  RGQLTALPEPLRLPGGEPVAAATAAGADPGKPADPGKLADPGKLADPGGQVVHQAAAGLG 247

Query: 232  -RLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFIN 290
             R+R +A  HG T    +L A+A VL R T   D+V G+ V  R DQ PG + ++G F N
Sbjct: 248  RRVRAFAAEHGATPFMVLLAAFAAVLHRHTGATDIVVGSPVVNR-DQ-PGADRLIGYFGN 305

Query: 291  AVPVVHYVSGTEA---VVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSLFV 344
             V +   V   ++   ++A+ ++  R + A + V    +       R  G   +F +LF 
Sbjct: 306  TVALRVRVRPGDSFRDLLARTSETCRGAFAHQHVDLEDVVRAVNPDRSDGVSSVFTTLFA 365

Query: 345  FENAP--------IDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXX 396
               A         +  A RP  T D AQF           PL V   +            
Sbjct: 366  VRTAAAEHLGARELSGARRPLHTGD-AQF-----------PLGVTVEIGADQLDLEAG-- 411

Query: 397  XXXXPYLPAAEIGERMLTVLRQLPDIGDGTPDD-------LDIRTAAELKAHGL-LAARS 448
                 +L AA        VLR L    D            +D+ T +E +   +     +
Sbjct: 412  -----FLTAAVTAGSAGAVLRHLETFLDHATRHPRRPLAAVDLLTDSERRRTLVDWNNTA 466

Query: 449  APTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVV 508
            AP+ D T  E+  R+              G   TY EL  RA  LA +L   G GP  +V
Sbjct: 467  APSPDATWAELLARRAARAPGHAAVVTSGGTL-TYGELVGRADALAYQLRGLGTGPGAIV 525

Query: 509  ALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQL--V 566
            AL LPR+                YLPVD   P+ R+  ++  A+P+L IT  + +    +
Sbjct: 526  ALALPRTLDLVVALAGVTRAGAAYLPVDPGYPADRITLVLEDAAPSLLITTRELAATLPI 585

Query: 567  GTAVPTLALDDPAAVESISRRSA----------AAPTVDRRPEQSAYVIFTSGSTGEPKG 616
               V  + ++ PAA                   AA  V      +AYVI+TSGSTG PKG
Sbjct: 586  PAGVTVVLVNGPAAGPEAGTEFGTEFGSVPEPPAAAAVPAELGSAAYVIYTSGSTGRPKG 645

Query: 617  VVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFD-ASWQPMVGLLDGHEIHL 675
            VV  + A+ ++ A   ++                   +LSFD A+ + +  L  G  +HL
Sbjct: 646  VVVPHRALTNFLASMVDQFQLGDGDRVLALT------TLSFDIAALELLAPLTAGATVHL 699

Query: 676  FDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLAL-GGEAINTGLW 734
               +E RD   L   +A G I +   TPSM+  + AA   D    V  L GGE +   + 
Sbjct: 700  AGQDEARDPTALAALLAGGGITVAQATPSMWQSILAASD-DRFPGVRVLSGGEGLPPAVA 758

Query: 735  DQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGV 794
              L   +   V N YGPTE T+           +PT+G     T  Y+ D+AL  V  G+
Sbjct: 759  ATLAERADEVV-NLYGPTETTIWSTAGPVAGDGRPTVGRPIRSTQVYLLDTALAPVAPGM 817

Query: 795  VGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADT 854
             GELY+ GA +A GY+ RPG+TA+RFVADP   G R+YRTGDL R  + G    +GR D 
Sbjct: 818  PGELYIGGAGVADGYLRRPGLTASRFVADPFSAGGRLYRTGDLARWTADGELDVLGRVDD 877

Query: 855  QVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTS---LVGFVV-WQDNMHEDLIK 910
            QVK+RG+R+E GE+EA L   P V  A  +V+ + D  +   LV +VV        D   
Sbjct: 878  QVKVRGFRIEPGEVEAVLGRHPAV--ARCAVVARDDGPAGRHLVAYVVPAAPGTVVDPAL 935

Query: 911  LRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDT 970
            LR  L   LP +MVP   V L  LP   NGKLD   L R       + +G  A   +T  
Sbjct: 936  LREHLAAALPEHMVPGAFVQLAALPTTPNGKLDRRGLPR---PDFAAAAGSRA--PATAA 990

Query: 971  ERVLCELFEEQLNAV-PHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQ 1029
            E +LC+LF   L       DD  F  G DSI+A  +V  AR  GL      +    T   
Sbjct: 991  ESLLCDLFGTVLGVERVGADDSFFHLGGDSILAFQVVAGARAAGLACVLPDIFRHPTPAS 1050

Query: 1030 LGAAIDAAV--DSQDAPADADYGAVRPLPMVSWLYEYGNYRRFT-----------HTVL- 1075
            L AA + A      D   DAD   V  + +  W   Y +                H++L 
Sbjct: 1051 LAAAAEQATVPPPADTALDADLAGVSAVDLERWRARYPDLTGVRPVSPLQAGLVFHSLLG 1110

Query: 1076 --------------------LRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGP-RL 1114
                                + L   +D + +    + L + H+ LR+      + P ++
Sbjct: 1111 DGSGTVPGAAGSDAYILQFVVDLRGRLDPARLRAAGRALFERHENLRTAFLYDGDAPVQI 1170

Query: 1115 VTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARV----VTDQIDPSAGAMVRAIWFR 1170
            V  + A    ++V T + L   +    A A+A A R+         D +A  +VR +  R
Sbjct: 1171 VLADLAPAAFDEVWTEVDL---AGWPRAEALAEAERLGRADRQTPFDLTAPPLVRFLLLR 1227

Query: 1171 GTEHRADPANILLLTAHHLAVDVVSWHIMLG------DLAAAWRSLQAGTPPKILPEFTS 1224
                    A  L+L+ HH+ +D  S  ++L       +LA +    QA  P   LP   S
Sbjct: 1228 ----TGPDAWRLVLSPHHVVLDGWSVPLLLRELFRRYELAQSQSQAQADGPAAALPPAPS 1283

Query: 1225 YRRWCELMWHRASAPQVQDQRDYWAALVREPDPAL----------------------GLR 1262
            Y  W  L W  A   +   +R + AAL    +P L                        +
Sbjct: 1284 Y--WEYLRW-LAGRDRDASRRAWAAALAGVTEPTLLAAATARPGTPAQTAAHAPDQVPEQ 1340

Query: 1263 YPDPTRDTWSTLQ-LTRAAIPVDVTERV---LGAVRRDQGVRELLLAATAMAVASWRRVR 1318
             PD   D W T+     AA+       +   LG   R++G+    +   A AV   R V 
Sbjct: 1341 APDQAVDQWDTVDGGVTAAVERHADAALTAGLGTFVRERGLTLNTVLRAAWAVVLGRAVG 1400

Query: 1319 AQDPAAGVLVA 1329
              D   G  VA
Sbjct: 1401 RDDVVFGTSVA 1411



 Score =  103 bits (256), Expect = 2e-19
 Identities = 153/553 (27%), Positives = 221/553 (39%), Gaps = 87/553 (15%)

Query: 911  LRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDT 970
            LRA LT  LP YMVPA  VTL  +P  ANGKLD  +L   A+ A+  V+   +  AS+  
Sbjct: 4121 LRADLTTALPDYMVPAAYVTLSEIPRTANGKLDVASLPP-ADPAVALVA---SRPASSPA 4176

Query: 971  ERVLCELFEEQLNAVPH--IDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTI 1027
            E  LCEL+ E L  +P   ++DD F  G  S++A  LV +AR   G  +  R +  A T+
Sbjct: 4177 EVTLCELYAEVL-GLPEVGVEDDFFALGGHSLLATRLVSRARAAFGADLAIRDLFEAPTV 4235

Query: 1028 RQLGAAIDAAVDSQD-------APAD-ADYGAVRPLPMVSWLYE--YGNYRRFTHTVLLR 1077
              L A + AA D           PAD  +   + P     WL +   G    + + +++R
Sbjct: 4236 AALAARVGAAGDEPAVSSRPPLVPADRPERIPLSPAQRRLWLVDRVAGGTNAYNYPLVIR 4295

Query: 1078 LPSGIDRSSIELMLQLLLDGHDTLRSILTE------------TPEGP--RLVTREPAAVR 1123
            L   ID  ++      +   H+ LR+++ E               GP  R V   PA   
Sbjct: 4296 LGGEIDLDALRAAAADVAARHEILRTVIAEHDGEDYQRILDPAEAGPEVRFVDVAPACPG 4355

Query: 1124 AEDVLTR--------ITLPEG--SDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTE 1173
            A              +  PE     DELA  V    R V +  D      +R   F    
Sbjct: 4356 APSAGAETGPAAEPSLDGPERPLEPDELARLV---ERFVAEPFDLRTDPPLRLAVF---- 4408

Query: 1174 HRADPA-NILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILP---EFTSYRRWC 1229
             R  PA ++L +  HH+A D  S    L DL AA+ + +AG  P   P   ++  Y  W 
Sbjct: 4409 -RTSPAESVLAVVLHHIATDEWSDRPFLEDLDAAYAARRAGREPDWDPLPVQYADYTLWQ 4467

Query: 1230 ELMWHRASAPQVQDQRD--YWAALVR--EPDPALGLRYPDPTRDTWSTLQLTRAAIPVDV 1285
              +    + P     R   YW   +R    +  L L  P P     +  +  R  +P   
Sbjct: 4468 RELLGEPADPSSPAGRQLAYWEQALRGIPAEIELPLDRPRPAVRDGAGGREAR-ELPAAT 4526

Query: 1286 TERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTT 1345
               + G   R  G    +LA  + A    R     D   GV +A    GR D  LD    
Sbjct: 4527 VTALRGLCAR-TGASMSMLAHASTATLLHRLGAGDDIPLGVPIA----GRTDTALD---- 4577

Query: 1346 NTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV 1405
            + VG+F N   +R    A          DP  A+ L  +  + L A  +  L +      
Sbjct: 4578 HLVGFFVNTLVLRSDLSA----------DPTFAELLARTRETDLAAFDHADLPF------ 4621

Query: 1406 DGVAELVDAVDPQ 1418
                ++V AV+P+
Sbjct: 4622 ---EDVVAAVNPR 4631



 Score = 78.2 bits (191), Expect = 9e-12
 Identities = 90/380 (23%), Positives = 141/380 (37%), Gaps = 57/380 (15%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            + LSP Q  L+ + ++A  G + Y+   V+ + G +DL+ LR +A  +  RH  LR    
Sbjct: 4266 IPLSPAQRRLWLVDRVA-GGTNAYNYPLVIRLGGEIDLDALRAAAADVAARHEILRTVIA 4324

Query: 72   DRD------------VPKPVQIVPVHAALPWSERVAT---------------PAEFDSIA 104
            + D                V+ V V  A P +                    P E D +A
Sbjct: 4325 EHDGEDYQRILDPAEAGPEVRFVDVAPACPGAPSAGAETGPAAEPSLDGPERPLEPDELA 4384

Query: 105  RSERR---RPFDLSRGPALRVVVL-SVPGETKRRMIFTAHHILVDGWSLAVFFTEL---L 157
            R   R    PFDL   P LR+ V  + P E+   ++   HHI  D WS   F  +L    
Sbjct: 4385 RLVERFVAEPFDLRTDPPLRLAVFRTSPAESVLAVVL--HHIATDEWSDRPFLEDLDAAY 4442

Query: 158  AVXXXXXXXXXXXXXXXXXXYIVWLAK---------QDRSAALAGWMDYLRGVSEPLMVA 208
            A                   Y +W  +               LA W   LRG+   + + 
Sbjct: 4443 AARRAGREPDWDPLPVQYADYTLWQRELLGEPADPSSPAGRQLAYWEQALRGIPAEIELP 4502

Query: 209  YE---ATAGQSKPGKTELLLPAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDV 265
             +           G+    LPAA    LR    R G +++     + A +L RL    D+
Sbjct: 4503 LDRPRPAVRDGAGGREARELPAATVTALRGLCARTGASMSMLAHASTATLLHRLGAGDDI 4562

Query: 266  VFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLS 325
              G  ++GR D    ++ +VG F+N + +   +S          + +    A  D + L 
Sbjct: 4563 PLGVPIAGRTD--TALDHLVGFFVNTLVLRSDLSADPTFAELLARTRETDLAAFDHADLP 4620

Query: 326  LSEI------QREHGRGPLF 339
              ++      +R  GR PLF
Sbjct: 4621 FEDVVAAVNPRRSAGRNPLF 4640



 Score = 55.5 bits (132), Expect = 6e-05
 Identities = 84/355 (23%), Positives = 136/355 (38%), Gaps = 29/355 (8%)

Query: 14   LSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDR 73
            LS  Q  L+ L Q+ E     Y++     ++GP+D+  LR +   ++ RH  LR  F   
Sbjct: 5392 LSHAQARLWVLGQV-EGPSPTYNIPVTWRLEGPLDVGALRAAVGDVVTRHEALRTVFPAP 5450

Query: 74   DVPKPVQIVPVHAALPWSERVATPAEFDSIARSERR--RPFDLSRGPALRVVVLSVPGET 131
            D     +++   AA    E +   +  D   R E    R FDL R   +RV  + +  + 
Sbjct: 5451 DGVPHQRVLDPAAARVDVELIELGSAGDLARRLENASARVFDLERELPVRVTAVRL--DP 5508

Query: 132  KRRMI-FTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAKQ----- 185
            +  ++ F  HHI  D  S      +L                     Y+ +   Q     
Sbjct: 5509 RLHVVQFLVHHIAADEGSDQALARDLSTAYRARLRGEAPRWAPLPVQYVDYTLWQRALLG 5568

Query: 186  ---DRSAALAGWMDYLRGVSEPLMVAYEATAGQSKP-------GKTELLLPAADTARLRQ 235
               D ++  +   D+ R     L V       +S+P       G  EL   A    RLR 
Sbjct: 5569 DESDPASPASAQRDFWRRELAGLPVELAVPTDRSRPAEPSHRGGVVELTWDAELLDRLRA 5628

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
             A  H ++L   +    A +L RL    D+  G+ V+GR D+   ++ +VG F+N + + 
Sbjct: 5629 TARAHDVSLFMVLQALVATLLHRLGAGDDIPIGSPVAGRGDE--RLDDLVGFFLNTLVLR 5686

Query: 296  HYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEI------QREHGRGPLFDSLFV 344
              +SG  +      +V+    A  D   L    +       R   R PLF  + V
Sbjct: 5687 TDLSGPVSFGELLGRVRAADLAAFDHQDLPFDRVVEAVNPPRSLARHPLFQVMVV 5741



 Score = 44.7 bits (104), Expect = 0.10
 Identities = 60/266 (22%), Positives = 85/266 (31%), Gaps = 42/266 (15%)

Query: 10   DVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAA 69
            D + + P    L AL + A  GVD +S   ++ +   V L  LR    A+ +RH  LRA 
Sbjct: 6513 DGVGVVPPTPPLLAL-RAAGGGVDGFSSPMLLHVPASVTLPALRAVLAAVAERHEILRAR 6571

Query: 70   F----------------------WDRDVPKPVQIVPVHAALPWSERVATPAEFD-----S 102
                                   W  DVP P           W  RV   A+ D     +
Sbjct: 6572 LVRAATGTVPDGLPATSADGGEAWYLDVPPPGPA----GVGSWVRRVEVGADDDLDRMLA 6627

Query: 103  IARSERRRPFDLSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXX 162
                   R  D   G  +RVV          R++   HH++ DG S  +   +L A    
Sbjct: 6628 AEALRANRELDPDAGAMVRVVWFDAGHSNSGRLLVLVHHLVTDGVSWQIILDDLAAAWNA 6687

Query: 163  XXXXXXXXXXXXXXXYIVW-------LAKQDRSAALAGWMDYLRG---VSEPLMVAYEAT 212
                           Y  W         + +R A LA W+  + G   +  P +   E  
Sbjct: 6688 LTRGGVPALAPVSTSYRRWALGVTEQARRPEREAELAYWLRTVEGGAPLPRPEIPEVERA 6747

Query: 213  AGQSKPGKTELLLPAADTARLRQWAG 238
            A +      E    A        WAG
Sbjct: 6748 APEHDTAVVERDAGAVTATIPETWAG 6773



 Score = 43.9 bits (102), Expect = 0.18
 Identities = 76/318 (23%), Positives = 123/318 (38%), Gaps = 64/318 (20%)

Query: 1078 LPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGS 1137
            L   +D  ++   L+ +  GH+ LR+             R PA  R E V+     P+ S
Sbjct: 22   LTGPVDADALHAALRAVARGHEILRTTY-----------RVPAGGRPEQVVHAELDPQWS 70

Query: 1138 DDELASAVAHAARVVTDQI---------DPSAGAMVRAIWFRGTEHRADPANILLLTAHH 1188
              +++   + +   + D+I         D ++ + +R    R    R     +L++ AHH
Sbjct: 71   SHDVSGEPSASRERLADEIARHAARRPFDLTSSSPLRVTLIRLAADRF----VLVVVAHH 126

Query: 1189 LAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQR--- 1245
            +A D  SW I   +L A + +L+AG  P  LP      ++ ++    A  P+  D +   
Sbjct: 127  VAWDDASWEIFFRELFAHYDNLRAGDGP--LPADERTAQYIDV----AGQPRGADAQDPD 180

Query: 1246 ----DYW-AALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVR 1300
                DYW   L   P+P   LR P       +T        P D  +        D G +
Sbjct: 181  PAALDYWRGQLTALPEP---LRLPGGEPVAAATAAGADPGKPADPGKLADPGKLADPGGQ 237

Query: 1301 ELLLAATAMAVASWRRVRAQDPAAG-----VLVA-----LEGH-GRADAVLDTDTTN--- 1346
             +  AA  +     RRVRA     G     VL+A     L  H G  D V+ +   N   
Sbjct: 238  VVHQAAAGLG----RRVRAFAAEHGATPFMVLLAAFAAVLHRHTGATDIVVGSPVVNRDQ 293

Query: 1347 -----TVGWFTNAFPVRL 1359
                  +G+F N   +R+
Sbjct: 294  PGADRLIGYFGNTVALRV 311


>tr|Q93N87|Q93N87_STRLA Tax_Id=1914 SubName: Full=Peptide
            synthetase;[Streptomyces lavendulae]
          Length = 4898

 Score =  673 bits (1736), Expect = 0.0
 Identities = 525/1543 (34%), Positives = 734/1543 (47%), Gaps = 98/1543 (6%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            Q+EDV  LSPLQEGL        DG D+Y  Q  +D+DGPVD +LLR S +A+L RHP L
Sbjct: 5    QVEDVWPLSPLQEGLLFHAAFDSDGPDVYQGQRPLDLDGPVDADLLRTSWEALLTRHPVL 64

Query: 67   RAAFWDRDVPKPVQIVPVHAALPWS-------ERVATPAEFDSIARSERRRPFDLSRGPA 119
            RA F  R   + VQ++     LPW        +     A    +A  +R + F+L+  P 
Sbjct: 65   RAGFRRRKSGEAVQVIAREVELPWRMEDLSELDEGTAAARLAELAAEDRAQRFNLAAPPL 124

Query: 120  LRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYI 179
            LR++++ +  E + R+I T+HHI++DGWS+ V   EL AV                  Y+
Sbjct: 125  LRLLLVRL-AENRHRLIVTSHHIIMDGWSMPVLLHELTAVYAAGGDAAKLPEPSSYRDYL 183

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELL-------LPAADTAR 232
             WL +Q++  A   W   L G  EP +VA       + PG+T +L       +P   T  
Sbjct: 184  AWLGRQNKDRAREAWRGELLGAEEPTLVA------AADPGRTPVLPESLIADIPEKLTGE 237

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L   A +HGLT+NT +  AWA+VL+RLT R DVVFG  V+GRP  L GVE+M+G+FIN +
Sbjct: 238  LTGLARQHGLTVNTLIQGAWAMVLARLTGRTDVVFGATVAGRPAGLAGVESMIGMFINTL 297

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDD 352
            PV   + G    V     +Q + SA+    +L L+EIQR  G G +FD+L VFEN P   
Sbjct: 298  PVRVELDGERPSVEMLKALQTRQSALIAHQHLGLAEIQRLGGAGAVFDTLVVFENYPRPP 357

Query: 353  AIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERM 412
               PA  PD         +   HYPLT+V+  +                    A  G R+
Sbjct: 358  E-EPAA-PDAFTLRFAAGQETAHYPLTLVAVPKDRMLFKLDYRPDLFDRETAEAVFG-RL 414

Query: 413  LTVLRQL---PDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXX 469
            + VL QL   P    G  D +       +  H    A   P    +V E+F RQV     
Sbjct: 415  VRVLEQLAADPLQPVGRVDAIGEAERTRVIDHWNSTATDRPA--ESVLELFARQV--VRT 470

Query: 470  XXXXXXXXGVRH-TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXX 528
                    G R  TYA+L   + +LA  LA+ GV     VA+VL RS             
Sbjct: 471  PHAIAISDGERQLTYAQLAVESGQLARHLADRGVSAGDRVAVVLERSADLLITLLAVWKA 530

Query: 529  XXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPT--LALDDPAAVESISR 586
               Y+PVD   P+ R+  ++    PA  +       +V   VP   + LD+ + ++    
Sbjct: 531  GAAYVPVDTAYPAERIAFLLTDCDPAAVVCSERTRVVVPEDVPAPLVPLDEASILDG--- 587

Query: 587  RSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXX 646
               + P         AYV++TSGSTG PKGV   + +V +   +    V           
Sbjct: 588  EPLSLPVAGG---DIAYVMYTSGSTGVPKGVAVPHGSVAALVGEPGWAV----GPGDSVL 640

Query: 647  XXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMF 706
                HA+ +S    W P   L  G  + + +   + DA  + E IA G +  +  T  +F
Sbjct: 641  FHAPHAFDISLFEVWVP---LASGARVEVAEPSVVVDAAAVREYIA-GGVTHVHVTAGLF 696

Query: 707  VQLSAAG--LLDHNLSVLALGGEAINTGLWDQLRGLS-QMAVYNCYGPTEMTV----EXX 759
              L+            VL  GG+ +      ++R    ++ V + YGPTE+++       
Sbjct: 697  RVLAEESPECFTGAREVLT-GGDVVPARAVQRVRSACPEVRVRHLYGPTEVSLCATWHLL 755

Query: 760  XXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAAR 819
                +  +   +G        YV D+ L  V  GV GELY++GA LARGY+ R G+++ R
Sbjct: 756  EPGEESPQVLPVGRPLGNRQVYVLDAYLHPVAPGVTGELYIAGAGLARGYLKRAGLSSER 815

Query: 820  FVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVH 879
            FVA P   G+RMYRTGDLVR  S G   +VGRAD QVK+RG+RVE+GE+EAAL  + GV 
Sbjct: 816  FVACPFADGERMYRTGDLVRWTSDGELVFVGRADAQVKVRGFRVELGEVEAALAAEAGVG 875

Query: 880  DAAVSVLRQQDRTS---LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPV 936
             A V+   ++DR     L+G+V+  D    D   LR  L + LP YMVPA ++ L  LP+
Sbjct: 876  HAVVTA--REDRPGERRLIGYVL-PDGEDVDTELLREHLAKVLPEYMVPAALIVLDALPL 932

Query: 937  NANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV-PHIDDDLFLF 995
             ANGK+D  AL   A D    V+G       TD ER LCE+F   L       +DD F  
Sbjct: 933  TANGKVDHKALP--APDFAVRVTGR---EPRTDAERTLCEIFAAVLGLERVGTEDDFFHL 987

Query: 996  GMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLG-AAIDAAVDSQDAPADADYGAVRP 1054
            G DSI ++ +V +A R  L + PR V    T  +L  AA  AA  +   P DA  G +  
Sbjct: 988  GGDSITSMQVVARAGRADLVLTPRQVFDLRTPERLAHAARPAATRTTTTPEDA-VGELPW 1046

Query: 1055 LPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRL 1114
             P++  +        F    ++  P+ +   ++   L  LLD HD LR+      + P L
Sbjct: 1047 TPVMRAMGRAAARPGFAQWAVVAAPTALGEETLTTALGTLLDTHDMLRA--RAAADTPTL 1104

Query: 1115 VTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEH 1174
            V  E  +V A  ++ R+ L   +D++    V  AAR   D +DP+AG MVR +W      
Sbjct: 1105 VVAERGSVDAAALVARVEL--RTDEDPDEVVERAAREAADGLDPAAGVMVRLVWVDAGPE 1162

Query: 1175 RADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWH 1234
            R   A  L+L  HHL VD VSW I+L DL  A  +  AG    + P  T +RRW +L+  
Sbjct: 1163 R---AGRLVLVVHHLVVDGVSWRILLPDLRVACEAAVAGRAADLDPVGTPFRRWAQLLEA 1219

Query: 1235 RASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQ---LTRAAIPV-DVTERVL 1290
             A   +   + D W  L+ + D  +G R  DP RDT +TL+    T +  P  D+  R+ 
Sbjct: 1220 EARDEKRIAELDRWRELLGDGDTLIGARALDPARDTAATLRHRSWTLSGAPAHDLIGRIS 1279

Query: 1291 GAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGW 1350
             A     GV E LLA  A AVA  R        + VLV +EGHGR     D D + TVGW
Sbjct: 1280 AAFH--CGVHEALLATLARAVARSR----SGADSAVLVDVEGHGREPLASDVDLSRTVGW 1333

Query: 1351 FTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGV 1408
            F +A PVRL    A +D+  A     AA  L+ +V     A+P DGL YGLLR++  D  
Sbjct: 1334 FADAHPVRL--DTADIDVADASAGGAAAGALLKAVKEQSRAVPGDGLGYGLLRHLNPDTA 1391

Query: 1409 AELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFV 1468
            + L     PQ+ F+YLGR      A        GP      I   PD PL   +  +  V
Sbjct: 1392 SALAQLPAPQVGFNYLGRFPAPTTA-----AAAGPSAPGGSI--APDTPLLHTVEAAAVV 1444

Query: 1469 GVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGL 1511
              T +G +L     W+  + +  D + L G W   +  LA  L
Sbjct: 1445 RDTPKGPELTLTLNWAGNILDAEDAERLGGTWLALLTGLATHL 1487



 Score =  637 bits (1642), Expect = e-180
 Identities = 504/1560 (32%), Positives = 726/1560 (46%), Gaps = 146/1560 (9%)

Query: 6    PQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPN 65
            P + DV  LSPLQEGL       + G D+Y  Q V+D+ GP+D + L RS   ++ RH  
Sbjct: 1518 PGLTDVWPLSPLQEGLLFHTAYDDQGPDVYETQRVLDLTGPLDADRLHRSWNTLVARHDM 1577

Query: 66   LRAAFWDRDVPKPVQIVPVHAALPWSE-------RVATPAEFDSIARSERRRPFDLSRGP 118
            LR +F +    + VQ V   A  PW E            AE +++A  ER   FDL+R P
Sbjct: 1578 LRVSFHELADGRTVQAVTGAAEPPWREVDLSDRPEPEALAEAEALAERERAERFDLTRAP 1637

Query: 119  ALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXY 178
             LR+ ++ + GE + R++ T+HHIL+DGWS  +   E   +                  +
Sbjct: 1638 LLRLFLVRL-GERRHRLVMTSHHILLDGWSTPIALDEASRIYAADGDASGLGPAPSFRDH 1696

Query: 179  IVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTE---LLLPAADTARLRQ 235
            + WLA+QD+  A   W   L G  EP ++A   T+    P  TE   LLL    T  L  
Sbjct: 1697 LAWLARQDKDTAHEAWRAELAGADEPTLIA--PTSAGRGPAATEGDSLLLSEELTRALTS 1754

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
             A  HGLTLNT    AWA+VLSRL  R DVVFG  V+GRP +LPGVE+MVG+F+N +PV 
Sbjct: 1755 VAREHGLTLNTLAQGAWALVLSRLARRTDVVFGISVAGRPPELPGVESMVGMFLNTLPVR 1814

Query: 296  HYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIR 355
              + G E+ V    ++Q + SA+    ++ L+EIQ   G G +FD++ +FEN P   +  
Sbjct: 1815 VRLDGAESAVRMLARLQDRQSALLAHQHVGLAEIQSLGGAGAVFDTMLMFENYPGGPS-H 1873

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
             A T D      V   + T YPL V                      +P    G+RM   
Sbjct: 1874 LAATDDEVTVERVNTRAGTSYPLAV--------------------GIMP----GDRMRVH 1909

Query: 416  LRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAP------------------------- 450
            +   PD+ D   + L +    E     L+A  +AP                         
Sbjct: 1910 VTYRPDLFD-RDEALHVARQVERVLEQLVADPAAPVGRVDVVGPLERGLVVEGWNTTTRR 1968

Query: 451  TFDTTVWEMFERQVQXXXXXXXXXXXXGVRH-TYAELHARACRLAGELAEHGVGPETVVA 509
            T  ++V E+F  +V             G R  +YAEL A +   A  L E GVG    VA
Sbjct: 1969 TLGSSVLELFRARVAQAPDAVAVVD--GERQVSYAELDAESNLAAAHLRERGVGRGDRVA 2026

Query: 510  LVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTA 569
            + L RS                Y+PVD   P+ RV  ++  +SPA+ I            
Sbjct: 2027 VRLERSIDLIAALLGVWKAGAAYVPVDGAYPAERVAFVLEDSSPAVTI------------ 2074

Query: 570  VPTLALDDPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFA 629
                        +++ +    AP+V       AYV++TSGSTG PKGV   + +V +   
Sbjct: 2075 ------------DAVVKGGGEAPSVAVTEGDLAYVMYTSGSTGTPKGVAVPHGSVAALVG 2122

Query: 630  DHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVE 689
            +                    HA+ +S    W P   L  G  + + +     DA  +  
Sbjct: 2123 ETG----WGLGPGDSVLFHAPHAFDISLFEVWVP---LASGARVVIAEPGVAVDAAAVRR 2175

Query: 690  GIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLAL-GGEAINTGLWDQLRGLS-QMAVYN 747
             IA G +  +  T  +F  L+       N +   L GG+ +      ++R    ++ V +
Sbjct: 2176 HIAAG-VTHVHVTAGLFRVLADEEPECFNGAHEVLTGGDVVPLEAVARVRAACPEVRVRH 2234

Query: 748  CYGPTEMTV----EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGA 803
             YGPTE+++              R   +G+  A    YV D+ L+ VP GV GELY++GA
Sbjct: 2235 LYGPTEVSLCATWHLLEPGEGTDRVLPVGSPLANRQVYVLDAFLQPVPPGVAGELYIAGA 2294

Query: 804  QLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRV 863
             LARGY+ R G++A RFVA P   G+RMYRTGDL R    G  A+ GRAD QVKIRG+RV
Sbjct: 2295 GLARGYLKRAGLSAERFVACPFADGERMYRTGDLARWTDDGELAFAGRADAQVKIRGFRV 2354

Query: 864  EVGEIEAALRGQPGVHDAAVSVLR-QQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSY 922
            E+GE+EAAL  QP V  A V     +     LVG++V      +  + LRA L + LP Y
Sbjct: 2355 ELGEVEAALAAQPAVAQAVVVAREGRPGEKRLVGYLVPHGGQPDSDV-LRARLAQTLPDY 2413

Query: 923  MVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQL 982
            MVPA +V L  LP+  NGK+D  AL      A  S    TA       E+++CELF + L
Sbjct: 2414 MVPAALVVLDALPLTVNGKVDHKALPAPEFTATASREPRTA------AEKLVCELFADVL 2467

Query: 983  NAVP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQ 1041
            N     + D  F  G DSI+++ L  +  R+G+    + V    T   + A    A D+ 
Sbjct: 2468 NLEQVGVADSFFELGGDSIMSMQLAARGNRKGIVFSAQDVFEHETPAAIAAVARLADDTG 2527

Query: 1042 DAPADADYGAVRP-LPMVSWL-------YEYGNYRRFTHTVLLRLPSGIDRSSIELMLQL 1093
               A+AD G   P  P++  L        E G   ++    ++ +P+ +D  ++ + L  
Sbjct: 2528 PETAEADSGGEVPWTPVMRALRDRAPRAVETGGLAQW---AVVAVPATLDEDTLAVGLGA 2584

Query: 1094 LLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVT 1153
            +LD HD LR+ +    E PRL   E  +V A  ++TRIT   G+ +ELA     AAR   
Sbjct: 2585 VLDTHDMLRARVEPGAE-PRLFVAERGSVDAAGLVTRITATVGALNELAD---RAARDAV 2640

Query: 1154 DQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAG 1213
             ++DP AG M +A+W             L+L  HHLAVD VSW ++LGDL AA     AG
Sbjct: 2641 TRLDPVAGVMAQAVWI----DAGPETGRLVLAVHHLAVDAVSWPVLLGDLRAACEDTDAG 2696

Query: 1214 TPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWST 1273
              P+      S+RRW E +   A       +   W  L+ + D  +G R  DP RDT ST
Sbjct: 2697 RQPEPARVGISFRRWAEKLAAEARKDSRVAELPAWTELLGDGDAPIGSRTLDPARDTAST 2756

Query: 1274 LQLTRAAIPVDVTERVLGAVRR--DQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALE 1331
            ++ +   +P      ++         GV E+LLA     +A WR   A++  A VL+ +E
Sbjct: 2757 VRRSTWTLPPAQARELVNRAPNAFHCGVHEVLLATLTGGIAQWRERTAEEGDAMVLLDIE 2816

Query: 1332 GHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEA 1391
            GHGR +A+   D + TVGWFT+  PVRL    A VD+  A     AA  L+ +V      
Sbjct: 2817 GHGR-EALDGVDLSRTVGWFTSVKPVRL--ETAGVDLADALAGGPAAGALLKAVKEQARR 2873

Query: 1392 IPNDGLDYGLLRYV--DGVAELVDAVDPQIQFSYLGRLDL-GGVADQPWSLLTGPYLDAL 1448
            +P DGL + LLR++  +    L +   PQ+ F+YLGR     G   +PW    G     +
Sbjct: 2874 LPGDGLGFELLRHLNPETAPALAELPVPQVGFNYLGRSTAPTGTGVEPWQATAG-----I 2928

Query: 1449 PIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
                +P  P++  +     V  T +G +L  +  W+  V + +D + L   W   +  LA
Sbjct: 2929 GGSVDPATPVKHVIEAGAAVRDTPDGPELTLSLSWAGEVLDTTDAEALGRAWLAMLNGLA 2988



 Score =  422 bits (1085), Expect = e-115
 Identities = 319/929 (34%), Positives = 441/929 (47%), Gaps = 61/929 (6%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            + AA   + DV  LSPLQEGL       E G D+Y  Q  +++ GP+D+  LR + QA++
Sbjct: 3017 IDAAVSALADVWPLSPLQEGLLFHAAYDEQGPDVYEGQRWLELTGPLDVARLRAAWQAVV 3076

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATP-------AEFDSIARSERRRPFD 113
             RH  LRA F   +  + VQ V     +PW     +        A F+ +A  ++   FD
Sbjct: 3077 ARHATLRAGFRQLESGRFVQTVARDIEIPWRAEDVSELPEAEALAAFERLAAEDQEHRFD 3136

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            ++  P LRV+++ +  E + R+ FT+HHI  DGWSL V  +E+  +              
Sbjct: 3137 IAHAPLLRVLLVRI-AERRHRLAFTSHHIASDGWSLPVMVSEVARLYEAGGDPRALPPAT 3195

Query: 174  XXXXYIVWLAKQDRSAALAGWMDYLRGVSEP-LMVAYEATAGQSKPGKTELLLPAADTAR 232
                Y+ WLA+QD+ AA A W   L  V EP L+V  +     ++P +    L      R
Sbjct: 3196 SYRAYLEWLARQDKEAARAAWRTELAPVDEPTLVVPADRVTAPAEPQRVTYELDEELGRR 3255

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L      H LTLNT +   WA++L+RLT R DVVFGT V+GRP +LPGVE+M+GLFIN +
Sbjct: 3256 LVALGRGHSLTLNTLLQGVWAILLARLTGRTDVVFGTTVAGRPTELPGVESMIGLFINTL 3315

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDD 352
            PV   + G + ++   T +Q +  A+    +L L+EIQR  G    FD+L V+EN P   
Sbjct: 3316 PVRVGLDGAQPLLEMLTDLQERQVALMSHQHLGLTEIQRLAGPAATFDTLVVYENYPRPP 3375

Query: 353  ---------AIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYL 403
                     +IRPA TP+ A           HYPLT+V+ L                   
Sbjct: 3376 LGSGDPDALSIRPAGTPEDA----------GHYPLTLVAVLEDERVRGDLVYRPDAFERA 3425

Query: 404  PAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAE----LKAHGLLAARSAPTFDTTVWEM 459
               E+   ++ +L QL          LD+  AAE    L      A    P     + E+
Sbjct: 3426 EVDELLTALVRILEQLVADPSAPVGRLDVTGAAERDMVLGEWNDTATADRPR--AALPEL 3483

Query: 460  FERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSX 519
            F  Q                  TYAEL   + RLA  L   GV  ET VAL++ RS    
Sbjct: 3484 FAAQAAHTPGNTALIGADR-ELTYAELERESGRLATHLRYLGVAAETRVALLVARSVEMV 3542

Query: 520  XXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVP--TLALD- 576
                        ++PVD   P+ R+  ++  A+P + +  A     V    P   + LD 
Sbjct: 3543 VALLGVSRAGGTFVPVDPAHPADRIAYLLEDAAPPVLLCTARTRAAVPADYPGRNVVLDE 3602

Query: 577  -DPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERV 635
             D +A+ +    +   P     P+Q+AYVI+TSGSTG PKGVV  +A + +  A   +R 
Sbjct: 3603 LDDSALPAEPFTATPVP-----PDQAAYVIYTSGSTGAPKGVVVPHAGLGNLAAAQIDR- 3656

Query: 636  YXXXXXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIG 694
                              SL FDA+  + ++ LL G    +  AE +     L E +   
Sbjct: 3657 -----FAVGPDARVLQLASLGFDAAVSELLMALLSGAAAIVAPAETLPPLVSLTEALRHW 3711

Query: 695  QIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEM 754
             +  +   PS    L+ A  L   L  L + GEA    L D+  G  +M   N YGPTE 
Sbjct: 3712 DVTHVTVPPS---ALATADELPDGLRTLVVAGEACPPALADRWAGGRRM--INAYGPTET 3766

Query: 755  TV--EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGR 812
            TV                +G   A    YV D  LR VP GV GELY++GA LARGY+G+
Sbjct: 3767 TVCASMSPPLAPGADVVPVGRPIANGRTYVLDPFLRPVPPGVTGELYVAGAGLARGYLGQ 3826

Query: 813  PGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
             G+TA RFV DP  PG+RMYRTGDL R    G   + GRAD QVK+RG+R+E GE+EA L
Sbjct: 3827 GGLTATRFVPDPFTPGERMYRTGDLARWTHDGLLVFAGRADAQVKVRGHRIEPGEVEAVL 3886

Query: 873  RGQPGVHDAAVSVLRQQ--DRTSLVGFVV 899
               PGV  AAV V R+       L+G+VV
Sbjct: 3887 AEHPGVAQAAV-VAREDTPGERRLIGYVV 3914



 Score =  206 bits (524), Expect = 2e-50
 Identities = 180/542 (33%), Positives = 254/542 (46%), Gaps = 71/542 (13%)

Query: 908  LIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSAS 967
            L +LR  +  RLP+YMVP   V + RLP+  NGKLD  AL   A D      G       
Sbjct: 4323 LAELREHVERRLPAYMVPTAFVPMDRLPLTPNGKLDRRALP--APDFAGRAGGR---DPR 4377

Query: 968  TDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATT 1026
            T  E +LC LF E L       DD  F  G DSI ++ L  +ARR+G+ + PR V    T
Sbjct: 4378 TPAEALLCRLFAEVLGLERVGADDSFFALGGDSITSMQLASRARREGVVLTPRQVFVEKT 4437

Query: 1027 IRQLGAAIDAAVDSQDAPADADYG-AVRPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRS 1085
              +L    +AA   + A  +  +  A+R +P    +            V L +P+G+D +
Sbjct: 4438 PERLALLAEAAAAEEAATGEVPWTPAMRAVPADGTVP--------AQWVELAVPAGLDPA 4489

Query: 1086 SIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAV 1145
            ++   L+ +LD H  LR  +     G  LV  EP A  A  ++ R+      DD +A AV
Sbjct: 4490 ALVRALRAVLDTHAMLRCRI-----GEELVVGEPGAPDAAGLIDRVDADTPLDDAVADAV 4544

Query: 1146 AHAARVVTDQIDPSAGAMVRAIWF-RGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLA 1204
            +        ++DP+ G +VR +W   G E R      L+L  H L VD  SW I++ DL 
Sbjct: 4545 S--------RLDPAEGVLVRLLWVDAGAESR------LVLVVHELVVDDESWRILVSDLR 4590

Query: 1205 AAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAAL--VREPDPALGLR 1262
             A+    AG  P + PE TSYRRW  L+  +A+A    ++ D WAA     EP PA G  
Sbjct: 4591 TAYEGAAAGQEPVLEPESTSYRRWARLLAEQATADARVEELDGWAAQSEAGEPSPAAGTE 4650

Query: 1263 YPDPTRDTWS-TLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQD 1321
                TR TWS T ++T       +T R       +    E++LAA   AV       A+D
Sbjct: 4651 ----TRATWSLTPEITAV-----LTHRTPETFHCEPS--EVVLAALVGAV-------AED 4692

Query: 1322 PAAGVL-VALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQD 1380
              A V+ + + G    D     D + TVG F +  PVR+    A VD+  A     AA +
Sbjct: 4693 GTATVMDLEISGRWPFDG---ADPSRTVGRFAHDIPVRV--ELAEVDLGSARAGGAAAGE 4747

Query: 1381 LVHSVVSHLEAIP-NDGLDYGLLRYVD--GVAELVDAVDPQIQFSYLGRL--DLGGVADQ 1435
            L+ +V   + A+P +DGL YGLLR+++    A L     P + F Y G    D G    +
Sbjct: 4748 LLKTVKEQVRAVPGDDGLGYGLLRHLNPRTAARLAALAPPTLAFGYHGHATPDTG----E 4803

Query: 1436 PW 1437
            PW
Sbjct: 4804 PW 4805



 Score = 50.1 bits (118), Expect = 0.002
 Identities = 92/357 (25%), Positives = 138/357 (38%), Gaps = 47/357 (13%)

Query: 1018 PRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPL-PMVSWLYEYGNYRRFTHTVL- 1075
            P + LT   + ++ AA+ A  D            V PL P+   L  +  Y      V  
Sbjct: 3005 PLLDLTQQEVAEIDAAVSALAD------------VWPLSPLQEGLLFHAAYDEQGPDVYE 3052

Query: 1076 ----LRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGP--RLVTRE-PAAVRAEDVL 1128
                L L   +D + +    Q ++  H TLR+   +   G   + V R+     RAEDV 
Sbjct: 3053 GQRWLELTGPLDVARLRAAWQAVVARHATLRAGFRQLESGRFVQTVARDIEIPWRAEDVS 3112

Query: 1129 TRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHH 1188
                LPE   + LA+    AA     + D +   ++R +  R  E R    + L  T+HH
Sbjct: 3113 E---LPEA--EALAAFERLAAEDQEHRFDIAHAPLLRVLLVRIAERR----HRLAFTSHH 3163

Query: 1189 LAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYW 1248
            +A D  S  +M+ ++A   R  +AG  P+ LP  TSYR + E +         QD+    
Sbjct: 3164 IASDGWSLPVMVSEVA---RLYEAGGDPRALPPATSYRAYLEWLAR-------QDKEAAR 3213

Query: 1249 AALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVD-VTERVLGAVRRDQGVRELLLAAT 1307
            AA   E  P        P     +  +  R    +D    R L A+ R   +    L   
Sbjct: 3214 AAWRTELAPVDEPTLVVPADRVTAPAEPQRVTYELDEELGRRLVALGRGHSLTLNTLLQG 3273

Query: 1308 AMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAA 1364
              A+   R     D   G  VA    GR   +   +  + +G F N  PVR+G   A
Sbjct: 3274 VWAILLARLTGRTDVVFGTTVA----GRPTELPGVE--SMIGLFINTLPVRVGLDGA 3324


>tr|C9Z1K9|C9Z1K9_STRSW Tax_Id=680198 SubName: Full=Putative
            NRPS/siderophore biosynthesis protein;[Streptomyces
            scabies]
          Length = 6352

 Score =  671 bits (1732), Expect = 0.0
 Identities = 529/1546 (34%), Positives = 732/1546 (47%), Gaps = 73/1546 (4%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            L LS  Q+ L+ L+Q+ E     Y++     + G +D+  LR +   ++ RH  LR  F 
Sbjct: 4820 LPLSSAQQRLWVLYQV-EGPSATYNIPSAWRLTGALDVAALRAAVHDVVLRHETLRTVFP 4878

Query: 72   DRDVPKPVQIV--PVHAALPWSERVATPAEF-DSIARSERRRPFDLSRGPALRVVVLSVP 128
            D D  +  Q+V  P    +P+ E V T  E    +        F L R   LRV V    
Sbjct: 4879 D-DGGRARQLVLAPDEVRVPF-EVVDTEEELLPELLAEAGAYGFALERELPLRVQVFRT- 4935

Query: 129  GETKRRMIFTAHHILVDGWSLAVFFTELL---AVXXXXXXXXXXXXXXXXXXYIVWLAK- 184
            GE +  ++   HHI  D WS      +L                        Y +W    
Sbjct: 4936 GEEEWTVLLLLHHIAGDEWSEGPLHRDLALAYGARTSGRAPEWEPLPVQYSDYTLWQRDV 4995

Query: 185  ------QDRSAA--LAGWMDYLRGVSEPLMVAYEATA---GQSKPGKTELLLPAADTARL 233
                  +D  AA  LA W   L G+ E L +  +         + G  +L L A   A L
Sbjct: 4996 LGDEKDEDSLAARQLAYWKRTLAGLPEELALPVDRARPLESTYRGGSADLSLDAELAAAL 5055

Query: 234  RQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVP 293
               A  +G+++   +  A A +LSRL    D+  G+ +SGR D    ++ +VG F+N + 
Sbjct: 5056 HVLARDNGVSVFMVLQAAVAGLLSRLGAGHDIPVGSPISGRTDA--ALDDLVGFFLNTLV 5113

Query: 294  VVHYVSGTEAVVAQCTQVQRQSSAM---RDVSYLSLSEI---QREHGRGPLFDSLFVFEN 347
            +    SG         +V+    A    +DV +  L E+    R   R PLF  + V+  
Sbjct: 5114 LRTDTSGNPTFRELLGRVRETDLAAFDHQDVPFERLVEVVNPARSLARHPLFQVMVVYLA 5173

Query: 348  APIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAE 407
            +  DD +      D  +    +  +        V                    +  A  
Sbjct: 5174 SGGDDTVLSGL--DTRRDDVAQTTAKFDLSFDFVERGDGSGVDGVLEYSADLFDHATAQS 5231

Query: 408  IGERMLTVLRQLPDIGDGTPDDLDIRTAAE-LKAHGLLAARSAPTFDTTVWEMFERQVQX 466
              +R+  VLR +    D    D+DI  A E  +  G   +R A    TTV  +FE QV+ 
Sbjct: 5232 FADRLRRVLRAVTADPDTALADVDILGADERARLVGGWHSRPAAGAPTTVPALFEEQVRL 5291

Query: 467  XXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXX 526
                       G+  T+AEL A A RLA  L   G GPE  VAL LPR+           
Sbjct: 5292 HGERPAAASD-GIELTFAELDADANRLARLLVAAGAGPERFVALALPRTAHFLTAVLAVH 5350

Query: 527  XXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISR 586
                 YLP+D   P  R  +++  A P L +T  D +  +      L LDD   V  ++ 
Sbjct: 5351 KAGAAYLPLDPDAPPERTAAVLADARPVLTLTTRDLAATLPPGTAPLVLDDGDTVARLAE 5410

Query: 587  RSAAAPT-VDRR----PEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXX 641
            +  A  T  DR     P   AYVI+TSGSTG PKGVV T+  + + F  H E +Y     
Sbjct: 5411 QDGAGLTDADRTAPLTPRHPAYVIYTSGSTGRPKGVVITHETLGNLFHSHRETLYAPAAE 5470

Query: 642  XXXXXXXXX-HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMID 700
                      HAWS  FDASWQP + LLDGH +H+   E  RD + + E +   + D ++
Sbjct: 5471 AAGRRHLRVGHAWSFFFDASWQPQLWLLDGHCVHVLSEEVRRDPELVTEAVLRHRFDFLE 5530

Query: 701  TTPSMFVQLSAAGLL---DHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVE 757
             TPS F Q++ +GLL   D  L+V+ +GGEA+   LW +L  L     +N YGPTE TV+
Sbjct: 5531 VTPSFFTQMADSGLLRGGDCPLAVVGVGGEAVPVALWKRLAELPGTEAFNLYGPTESTVD 5590

Query: 758  XXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTA 817
                   D  +P +G   AGT  YV D  L+ +P GV GELYL+G  LARGY+G P +TA
Sbjct: 5591 ALVGRVGDSERPLVGRPVAGTRAYVLDDRLQPLPPGVPGELYLAGGGLARGYLGGPALTA 5650

Query: 818  ARFVADPLRP-GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQP 876
             RFVADP  P G R+YRTGDL R  + G   Y+GRAD QVKIRG+R+E  EIEAAL   P
Sbjct: 5651 ERFVADPFGPAGSRLYRTGDLARWTADGRIDYLGRADDQVKIRGFRIEPAEIEAALTSHP 5710

Query: 877  GVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPV 936
             V  A V+V +   R  LV  VV   +   D  +LRA +  RLP +MVPA +VTL R P 
Sbjct: 5711 EVGQALVTVHQDGPRKLLVAHVVPAPDTAPDPARLRAHVGGRLPDHMVPAAVVTLERFPR 5770

Query: 937  NANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLF 995
             ANGKLD  AL   A D   ++S G A   +T  E +LC +F E L  +   +DDD F  
Sbjct: 5771 LANGKLDRSALP--APD-FAALSSGRA--PATPVEELLCTVFAEVLGLSRVGVDDDFFAL 5825

Query: 996  GMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPL 1055
            G DSIVA+ LV +AR  GLR+ PR+V    T+  LG   +AA  S   P D   G+V   
Sbjct: 5826 GGDSIVAMQLVGRARAAGLRISPRLVFRHRTVAALGTVAEAADVSVPRPVDDGTGSVPLT 5885

Query: 1056 PMVSWLYEYGN-YRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILT----ETPE 1110
            P++ WL E G  +  +    L+R P+ +D   +  +LQ L D HD LR+ L     E  E
Sbjct: 5886 PVMQWLRELGGPFASYHQAALVRTPAALDLPGLTAVLQALADRHDLLRATLVRPSREDTE 5945

Query: 1111 GPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFR 1170
               L       V A   + R+ +       L   V     V    +DP AG +VRA+WF 
Sbjct: 5946 EWSLHVPPAGTVDAAGWIERVDVSGLDAAALGETVRAHTAVARASLDPDAGVVVRAVWF- 6004

Query: 1171 GTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCE 1230
                  D    LLL  HHL VD VSW ++L DL AAWR + AG P  +LP  TS+ RW  
Sbjct: 6005 ---DAGDAPGRLLLMGHHLVVDGVSWRVLLPDLEAAWRDVSAGRPVALLPVETSFARWSR 6061

Query: 1231 LMWHRASAPQVQDQRDYWAALVREPDPALGL-RYPDPTRDTWSTLQLTRAAIPVDVTERV 1289
            L+   A AP+ + +   W A++     +L L R  D  RDT +T +     +P + T  +
Sbjct: 6062 LLTELAQAPEGEAELPLWEAILDGGAQSLPLTRARDADRDTAATRREVVLRLPAERTGPL 6121

Query: 1290 LGAVRR--DQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAV--LDTDTT 1345
            L AV      GV ++LLA  A+A A  R+ R       +LV LEGHGR + +     D +
Sbjct: 6122 LSAVPAAFGAGVNDVLLAGLALAFADLRK-RNGGTDTSLLVDLEGHGREEELGGDGVDLS 6180

Query: 1346 NTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV 1405
             TVGWFT+ +PVRL  G A  D   A     AA++ V  V +HL A+P +G+ YGLLR++
Sbjct: 6181 RTVGWFTSVYPVRLDPGPA--DPADAFAGGPAAEEAVRRVRAHLAALPANGVGYGLLRHL 6238

Query: 1406 D-GVAELVDAVD-PQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALN 1463
            +    E++ A + P+++F+YLGR   G   +  WS    P  DA  I  E       AL 
Sbjct: 6239 NPRTREVLAAYEPPRVEFNYLGR--FGVPEETDWSY--APEEDAADIGSEGSTREGHALE 6294

Query: 1464 LSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            ++V     A+G  L  +W + + +  R  +  L   W R +  L A
Sbjct: 6295 INVVTEDRADGPVLAAHWSYLEGLLPRDTVRDLAETWFRALEGLVA 6340



 Score =  508 bits (1309), Expect = e-141
 Identities = 486/1495 (32%), Positives = 674/1495 (45%), Gaps = 159/1495 (10%)

Query: 8    IEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLR 67
            ++++L L+PLQ+G F  H L     D Y +Q V+D+ GPVD  LLRR+AQ +LDRH  LR
Sbjct: 1245 VDELLPLTPLQQGFF-FHALTGGDGDTYVVQQVLDLAGPVDASLLRRAAQQLLDRHSPLR 1303

Query: 68   AAFWDRDVPKPVQIVPVHAALPWSERVATPAEF-------DSIARSERRRPFDLSRGPAL 120
            AAF  R    PVQI+  +A LPW E   +  +        D++A  ER R FDL+  P L
Sbjct: 1304 AAFRQRPDGTPVQIITRNAELPWREVDLSAQDGGIRESLGDAVAADERARGFDLAAPPLL 1363

Query: 121  RVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIV 180
            R  ++ + GE + R++ T HHI+ DGWSL V   EL+A                   ++ 
Sbjct: 1364 RCALIRL-GEERSRLVLTFHHIVADGWSLPVLHRELMAFYGTDAPTLPAVAPYRG--FLR 1420

Query: 181  WLAKQDRSAALAGWMDYLRGVSEPL-MVAYEATAGQSKPGKTELLLPAADTARLRQWAGR 239
             LA+QD  AA A W D L G+ EP  +V   A     +P    + L    TARL + A  
Sbjct: 1421 RLAEQDGDAARAAWADALAGLDEPTRLVGDPADTAPVRPEHVRVELSERTTARLAERARA 1480

Query: 240  HGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVS 299
            +G+TL T V  AW ++L RLT R D+VFGT VSGR  ++ G+ +MVGLFIN +P     +
Sbjct: 1481 YGITLGTIVQGAWGLLLGRLTGRDDLVFGTTVSGRDGEVEGIASMVGLFINTLPTRFRWT 1540

Query: 300  GTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQR---EHGRGPLFDSLFVFENAPIDDAIRP 356
              E++     ++Q + + + D  +L L+EIQR     G G LFD+L VFEN P ++ +R 
Sbjct: 1541 PRESLGTLLVRLQEEQARLLDHQHLGLAEIQRLSGHAGSGELFDTLVVFENYPAENGLRD 1600

Query: 357  ATTPDGAQFLPVEMESLTHYPLT-VVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
            A+     +          HYPL  VV   R                   A  +G R+  V
Sbjct: 1601 ASGT--VRITGDAFHDAVHYPLALVVKPGRRLDLRLKHHAERLDGD--TARMLGGRLARV 1656

Query: 416  LRQLPDIGDGTPDDLDIRTAAE-LKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXX 474
            L  + +  D     +D+ +  E L+AH     ++ P   TT+ E F  QV          
Sbjct: 1657 LEAVAESPDRAAASVDLLSPDEALRAHPAGEEQALP--GTTLAEGFAAQVARTPDAPAVV 1714

Query: 475  XXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLP 534
               G R +YAEL ARA  LA  L   G  P T VA+ +PRS                YLP
Sbjct: 1715 FG-GERLSYAELDARAEELAIRLRRRGARPGTFVAVAVPRSAELMVALLGVLKSGAAYLP 1773

Query: 535  VDVTLPSARVESIVRQASPALAIT-EADYSQLVGTAVPT-LALDDPAA------------ 580
            VD+  P+ RV  ++  +     +T  A   +L G A+P+ L LD P              
Sbjct: 1774 VDLDYPADRVTHMLTDSGATTVVTLSATADRLPGQALPSVLLLDTPDTPDTHDASDTHDG 1833

Query: 581  ---VESISRRSAAAPTVD-RRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVY 636
               ++ +     A  + D  RP+  AY+I+TSGSTG PKGVV T+ A+++  A      +
Sbjct: 1834 LDDLDGLGGEPPAGRSADPARPDDPAYLIYTSGSTGVPKGVVVTHRAIVNRLA------W 1887

Query: 637  XXXXXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQ 695
                               SFD S W+    LL+G  + L   +  RD   L   +    
Sbjct: 1888 MQAAYGLASDDRVLQKTPSSFDVSVWEFFWPLLEGASVVLARPDGHRDPAYLAGLVREQA 1947

Query: 696  IDMIDTTPSMFV------QLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCY 749
            +  +   PSM        +++       +L  +   GEA+      +   L+ + ++N Y
Sbjct: 1948 VTTMHFVPSMLEAFLGHDEVTGDPAWSASLRRVLSSGEALPATAASRWHALTGVPLHNLY 2007

Query: 750  GPTEMTVEXXXXXXK-DYRKPT---IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQL 805
            GPTE  V+        D  + T   IG     T   V D+ LR VPDGV GELYL+G QL
Sbjct: 2008 GPTEAAVDVTYHPYAPDEDRGTAVPIGRPVWNTGLRVLDACLRPVPDGVPGELYLTGVQL 2067

Query: 806  ARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVE 864
            ARGY  RP +TA RF ADP  RPG RMYRTGDLVRR + G   Y+GR D QVK+RG R+E
Sbjct: 2068 ARGYHARPALTAERFTADPYGRPGSRMYRTGDLVRRRADGVIEYLGRTDRQVKLRGNRIE 2127

Query: 865  VGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMV 924
            +GE+EAAL   P V  AAV+V       +LV +VV       +   LR  +T  LP+ MV
Sbjct: 2128 LGEVEAALVRLPEVAQAAVTVRDD----ALVAYVVPAPGAAAEADDLRESVTGSLPAPMV 2183

Query: 925  PARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA 984
            P+  V L  LP+  +GK     LDR A  A  +V G    +  T  E++L E+F   L  
Sbjct: 2184 PSAWVVLDALPLTPSGK-----LDRTALPAPQAVRGTVTRAPGTPREQLLVEIFAAVLKL 2238

Query: 985  -VPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDA 1043
                +DDD FL G DSI +I++  +ARR GL + PR V    T   L A   A +D +DA
Sbjct: 2239 DEVGVDDDFFLLGGDSISSIAVSSRARRAGLAIGPREVFEHRTPAALAAT--ATLDERDA 2296

Query: 1044 P---------------------ADADYGAVRPL-PMVSWLYEYGNYRR-----FTHTVLL 1076
                                  A      V PL P+   L+ + N+       +T     
Sbjct: 2297 GDTLAASAFTLTEEEREHVERLAPGRIEDVWPLAPLQEGLFFHSNFDAGSLDVYTVHESF 2356

Query: 1077 RLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRIT---- 1132
                 +D   +   ++ LLD + +LR+  T   EG     R PA     D    +T    
Sbjct: 2357 DFADRVDAERLTAAVRTLLDRNPSLRAGFTS--EG----LRRPAQFIVRDAAIPLTEVDL 2410

Query: 1133 --LPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLA 1190
              LP    D     +   +R    + D +   + R +  R  E R D    L++  H + 
Sbjct: 2411 AGLPAAEQDARMRELLEESR--ARRFDLARPLLFRMLLVRLGEERGDR---LIVGRHLIL 2465

Query: 1191 VDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAA 1250
             D  S  + L  L A + S   G  P  L    SYR +  L W        +  R + AA
Sbjct: 2466 WDGWSAWLFLDQLFALYES---GGDPAGLARPGSYRDY--LTWLERQ-DDTEATRAWRAA 2519

Query: 1251 L--VREPD---PALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLA 1305
            L    EP    PA   R  +P        QL  A +   V ER L  + R QG     L 
Sbjct: 2520 LSGFEEPTLLVPAASERGQEPV----IPAQLD-AVLDAPVAER-LRDLARSQG-----LT 2568

Query: 1306 ATAMAVASWRRVRA-----QDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLG 1360
               +  A+W  V A      D A G  VA    GR   V D +  + +G F N  P R+ 
Sbjct: 2569 LNTVLNAAWGLVLAGATGRTDVAFGTTVA----GRPSEVPDVE--HVIGMFLNTVPARI- 2621

Query: 1361 AGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAV 1415
                A D     R+PV    L       LE +P + L  G+L+   G   L D +
Sbjct: 2622 ----AFD----PREPVLGL-LRRIQGERLEVMPYEHLGLGVLQAESGHRRLFDTL 2667



 Score =  471 bits (1213), Expect = e-130
 Identities = 328/940 (34%), Positives = 454/940 (48%), Gaps = 46/940 (4%)

Query: 4    AAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRH 63
            A  +IEDV  L+PLQEGLF         +D+Y++    D    VD E L  + + +LDR+
Sbjct: 2319 APGRIEDVWPLAPLQEGLFFHSNFDAGSLDVYTVHESFDFADRVDAERLTAAVRTLLDRN 2378

Query: 64   PNLRAAFWDRDVPKPVQIVPVHAALPWSE-------RVATPAEFDSIARSERRRPFDLSR 116
            P+LRA F    + +P Q +   AA+P +E            A    +    R R FDL+R
Sbjct: 2379 PSLRAGFTSEGLRRPAQFIVRDAAIPLTEVDLAGLPAAEQDARMRELLEESRARRFDLAR 2438

Query: 117  GPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXX 176
                R++++ +  E   R+I   H IL DGWS  +F  +L A+                 
Sbjct: 2439 PLLFRMLLVRLGEERGDRLIVGRHLILWDGWSAWLFLDQLFALYESGGDPAGLARPGSYR 2498

Query: 177  XYIVWLAKQDRSAALAGWMDYLRGVSEP-LMVAYEATAGQSK--PGKTELLLPAADTARL 233
             Y+ WL +QD + A   W   L G  EP L+V   +  GQ    P + + +L A    RL
Sbjct: 2499 DYLTWLERQDDTEATRAWRAALSGFEEPTLLVPAASERGQEPVIPAQLDAVLDAPVAERL 2558

Query: 234  RQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVP 293
            R  A   GLTLNT +  AW +VL+  T R DV FGT V+GRP ++P VE ++G+F+N VP
Sbjct: 2559 RDLARSQGLTLNTVLNAAWGLVLAGATGRTDVAFGTTVAGRPSEVPDVEHVIGMFLNTVP 2618

Query: 294  VVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDA 353
                    E V+    ++Q +   +    +L L  +Q E G   LFD+LFV  NA  D+ 
Sbjct: 2619 ARIAFDPREPVLGLLRRIQGERLEVMPYEHLGLGVLQAESGHRRLFDTLFVLRNADTDER 2678

Query: 354  IRPATTPDGAQFLPVEMESLTHYPLT-VVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERM 412
            +       GA    V     THYP   VV+                   Y  A  + +R 
Sbjct: 2679 LADLRERHGAT--AVANVDATHYPANLVVTPGERVRATLAYRPDLLDGAY--ARSLLDRF 2734

Query: 413  LTVLRQL---PDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXX 469
            + ++ +L   P    G+ D L    AA L      A +  P    TV +M   Q      
Sbjct: 2735 VLLVSRLVADPHAPVGSLDPLLPAEAAALAREE--AEQRQPVPHETVADMLAAQAARTPD 2792

Query: 470  XXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXX 529
                        TYAEL AR  R+A  L   G GPE V+AL LPRS              
Sbjct: 2793 ETALVFGAQTL-TYAELDARCDRMARLLIARGAGPEQVIALGLPRSIDMVVALFAVLRTG 2851

Query: 530  XXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSA 589
              YLP+++  P+ R+  ++  A P L ++ A  S  +    P + LDDPA    ++    
Sbjct: 2852 SAYLPLELDHPADRLSLMLADARPLLLLSTAGVSATLTGDTPRVLLDDPAVAAELASFPT 2911

Query: 590  AAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXX 649
               +V    +  AYVI+TSGSTG PKGVV     + +   +H + ++             
Sbjct: 2912 GPVSVSFSLDHPAYVIYTSGSTGRPKGVVTPYLGLTNMQLNHQKEIFAPAIASAGGRRLR 2971

Query: 650  X-HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQ 708
              H  S +FD SW+ ++ L++GHE+H+ D E  RDA  LV      ++D+++ TP+    
Sbjct: 2972 IAHTVSFAFDMSWEELLWLVEGHEVHVCDEELRRDATALVAYCEEHRVDVVNVTPTYAHL 3031

Query: 709  LSAAGLLD-HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYR 767
            L   GLL+ H   ++ LGGEA+   +W+ LR       YN YGPTE T+       +D  
Sbjct: 3032 LLEEGLLEGHRPPLVLLGGEAVTETVWNTLRDTEGTYGYNLYGPTEYTINTLGGGTEDSA 3091

Query: 768  KPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-R 826
             PT+G     T   V D+ LR VPDGV GELY++G  LARGY+ RPG+TA RFVADP  R
Sbjct: 3092 TPTVGRPIRATRARVLDTWLRPVPDGVAGELYIAGVGLARGYLDRPGLTAERFVADPYGR 3151

Query: 827  PGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVL 886
            PG+RMYRTGDLVRR   G   ++GR D QVKIRG+RVE+GEIE AL   P V  AAV   
Sbjct: 3152 PGERMYRTGDLVRRRPDGNLDFLGRTDDQVKIRGHRVELGEIETALGQHPEVSRAAVVA- 3210

Query: 887  RQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPA 926
              +D T+  G                   T+RL  Y+VPA
Sbjct: 3211 --RDDTAAPG-------------------TKRLVGYVVPA 3229



 Score =  396 bits (1017), Expect = e-107
 Identities = 410/1393 (29%), Positives = 592/1393 (42%), Gaps = 96/1393 (6%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            + LS  Q  L+ + ++  DGV  Y+   V  + G +DL+ LR + + +  RH  LR  F 
Sbjct: 3773 IPLSAAQRRLWLVERITGDGV-AYNFPLVFRLRGTLDLDALRAALRDVTVRHEALRTRFV 3831

Query: 72   DRDVPKPVQIVPVHAALPWSERVATPAEFDSIAR---SERRRPFDLSRGPALRVVVLSVP 128
            + D      I     A P  E   T A+   IA+     +RRPFDL     +R  VL + 
Sbjct: 3832 EADGEPYQWIAAPGEAEP--EFRLTEADESRIAQWIEEAQRRPFDLGTELPVRTEVLRLA 3889

Query: 129  GETKRRMIFTAHHILVDGWSLAVFFTEL---LAVXXXXXXXXXXXXXXXXXXYIVW---L 182
             +    +    HHI  D WS   F  +L    A                   + +W   L
Sbjct: 3890 ADD-HVVAVVLHHITTDEWSDRPFLADLHRAYAARAAGAAPDWAPLPVQYADHTLWQERL 3948

Query: 183  AKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELL---LPAADTARLRQWAGR 239
              +     LA W   L G+   + +  +        G+  ++   LP A    LR  AG 
Sbjct: 3949 LTEVEDDQLAYWTGALSGLPAEIPLPLDRPGAPRATGRGAVVRATLPGATGDALRDLAGT 4008

Query: 240  HGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVS 299
            H +++      A A +L RL    D+  G  ++GR D    V+ +VG F+N + +   +S
Sbjct: 4009 HQVSMFMLFQAATAALLHRLGAGDDIPLGAPIAGRTDS--AVDDLVGFFVNTLVLRTDLS 4066

Query: 300  GT---EAVVAQCTQVQRQSSAMRDVSYLSLSEIQ---REHGRGPLFDSLFVFENAPIDDA 353
            G    EA++ +  +    +   +DV +  + E     R   R PLF  +  + + P  D 
Sbjct: 4067 GAPSFEALLGRVREAALAAFEHQDVPFDRVVEAVNPVRTADRNPLFQVMLGYHHRPDGD- 4125

Query: 354  IRPATTPDGAQFLPVEMESLTHYPL--TVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGER 411
              P       ++  ++   +  + L  T V H                     A  +  R
Sbjct: 4126 --PELFGLPTEWFDMD-NGMAKFDLDFTFVDHGPGRDLALLLEYATDLADEETAVSLAGR 4182

Query: 412  MLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXX 471
            +L +L ++           D+RT  E  A     AR   T   +V E+ +  V+      
Sbjct: 4183 LLGLLERVVAEPGRPLRSFDLRTEVERTAVWNDTARPLET--RSVPEILDDVVRSRPDAP 4240

Query: 472  XXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXX 531
                    R T+ EL  R   +A  L   G  PE VV L LPR                 
Sbjct: 4241 ALTTGVS-RLTFRELGERVDAVARLLLRRGAAPERVVGLALPR-HLMVPALLGVLKSGAA 4298

Query: 532  YLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAA 591
             LP+D   P+ R+E ++R A+P   ++ A+ +  +    P + +DD    E       A 
Sbjct: 4299 CLPLDPEHPTERMEFMLRDAAPLCVLSTAELAAKLPEGAPVVLIDDLVPDEG-----EAP 4353

Query: 592  PTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAER-VYXXXXXXXXXXXXXX 650
              V   P  +AYVIFTSGSTG PKGVVGT+  + + FA H +  +               
Sbjct: 4354 AVVPPAPSGTAYVIFTSGSTGTPKGVVGTHRGLSNLFAAHRDDLIRPAERSLGRDRLRAV 4413

Query: 651  HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLS 710
            HA S SFD SW+P++ LL GHE+ + +   M D   L+  +    ID +D TP+   +L 
Sbjct: 4414 HAASFSFDGSWEPLLWLLAGHEVQVVEEAVMADPAALLAHLCREDIDFLDVTPTYLRELI 4473

Query: 711  AAGLLDHNL---SVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYR 767
              G L+       V+A+GGEA    LW++L  L  + V++ YGPTE  V+          
Sbjct: 4474 HHGFLEPGTPLPGVIAVGGEATPAPLWERLCALPGVQVHDLYGPTESAVDAYGWHSDATG 4533

Query: 768  KPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-R 826
            +      N     +V D  LR VP GV GELYL+G  LARGY+ RPG+TA RF ADP   
Sbjct: 4534 RWAAPLDNIRA--HVLDELLRPVPAGVTGELYLAGEGLARGYLNRPGLTAERFTADPFGA 4591

Query: 827  PGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVL 886
            PG RMYRTGDLVRR   G   ++GRAD QVK+RG+R+E GEIEA L   P V  AAV V 
Sbjct: 4592 PGSRMYRTGDLVRRRRDGSLEFLGRADGQVKLRGFRIEPGEIEALLARHPDVATAAVVVR 4651

Query: 887  RQQDRT-SLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGH 945
                    LV +V+       D  +LR      LP++MVP+  VT+P LP    GKLD  
Sbjct: 4652 EDTPGVRRLVAYVLPAAGRTPDPAELRGHTAGALPAHMVPSAFVTVPALPRTVAGKLDTQ 4711

Query: 946  ALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPH--IDDDLFLFGMDSIVAI 1003
            AL   A D   SVSG       T  E +LCE F   L  VP   +DDD F  G  S++A+
Sbjct: 4712 ALP--APDLGASVSGR---RPRTPREDLLCEAFAAVL-GVPEAGVDDDFFALGGHSLLAM 4765

Query: 1004 SLVHKARRQ-GLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRP--LPMVS- 1059
             L  + R   G  V  R V  A T  +L   +   VD+      A     RP  LP+ S 
Sbjct: 4766 RLTARVRAALGAEVSLRTVFDAPTPARLARHLAGGVDTAGTTRPALTVRERPARLPLSSA 4825

Query: 1060 ----W-LYEY-GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPR 1113
                W LY+  G    +      RL   +D +++   +  ++  H+TLR++  +     R
Sbjct: 4826 QQRLWVLYQVEGPSATYNIPSAWRLTGALDVAALRAAVHDVVLRHETLRTVFPDDGGRAR 4885

Query: 1114 LVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTE 1173
             +   P  VR    +   T  E   + LA A A+   +  +         +R   FR  E
Sbjct: 4886 QLVLAPDEVRVPFEVVD-TEEELLPELLAEAGAYGFALERE-------LPLRVQVFRTGE 4937

Query: 1174 HRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMW 1233
                    +LL  HH+A D  S   +  DLA A+ +  +G  P+  P    Y  +   +W
Sbjct: 4938 EEW----TVLLLLHHIAGDEWSEGPLHRDLALAYGARTSGRAPEWEPLPVQYSDY--TLW 4991

Query: 1234 HRASAPQVQD-------QRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDV- 1285
             R      +D       Q  YW   +      L L   D  R   ST +   A + +D  
Sbjct: 4992 QRDVLGDEKDEDSLAARQLAYWKRTLAGLPEELALPV-DRARPLESTYRGGSADLSLDAE 5050

Query: 1286 TERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTT 1345
                L  + RD GV   ++   A+A    R     D   G  ++    GR DA LD    
Sbjct: 5051 LAAALHVLARDNGVSVFMVLQAAVAGLLSRLGAGHDIPVGSPIS----GRTDAALD---- 5102

Query: 1346 NTVGWFTNAFPVR 1358
            + VG+F N   +R
Sbjct: 5103 DLVGFFLNTLVLR 5115



 Score =  221 bits (562), Expect = 8e-55
 Identities = 165/425 (38%), Positives = 213/425 (50%), Gaps = 27/425 (6%)

Query: 482 TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPS 541
           TYAEL +RA RLA  L   G GPE +VAL LPRS                YLP+D   P+
Sbjct: 250 TYAELDSRANRLAHALLARGAGPERIVALALPRSAELFVAEVAVLKSGAAYLPIDHDYPA 309

Query: 542 ARVESIVRQASPALAITEADYS-QLVGT--AVPTLALDDPAAVESISRRSAAAP-TVDRR 597
            R+  ++  A P   +T A  + +L G    +  L LD PA    ++ R    P   DR 
Sbjct: 310 DRIAYMLGDARPVCMVTTAQTARELPGPDDGMTVLELDAPATAAELAGRPDHDPGEADRG 369

Query: 598 PE----QSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAW 653
                  SAYVI+TSGSTG PKGV  ++  V    A  +ER                   
Sbjct: 370 GPLTVLNSAYVIYTSGSTGRPKGVALSHGGVAKLVATQSERFGIGPHSRVLQFA------ 423

Query: 654 SLSFD-ASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA 712
           S SFD A W   +GLL G  + +  AE       L +      +  +   P++   +   
Sbjct: 424 SPSFDVAFWDLCLGLLSGGRLVVVPAELRVPGAPLADYADAHGVTFMILPPALLAAMPED 483

Query: 713 GLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPT-- 770
             L    ++LA G E ++  L  +      M  +N YGPTE T         D   P   
Sbjct: 484 VRLPPTATLLA-GTERVSPELVGRYARGRMM--FNAYGPTEATTNSTLGLC-DPDIPAGA 539

Query: 771 ---IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-R 826
              IG  + GT  YV D+ LR VP GV GELYL GA LARGY+GRP +TA RFVADP   
Sbjct: 540 IVPIGVPDPGTRAYVLDAYLRPVPAGVTGELYLGGAGLARGYLGRPDLTAERFVADPFGE 599

Query: 827 PGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVL 886
           PG+R+YRTGDLVR  + G   ++GRAD QVKIRG+R+E GEIE+ LRG P V    V+V+
Sbjct: 600 PGERLYRTGDLVRWQADGRLEFLGRADAQVKIRGFRIEPGEIESVLRGHPAVDQ--VTVV 657

Query: 887 RQQDR 891
            ++DR
Sbjct: 658 VREDR 662



 Score =  100 bits (250), Expect = 1e-18
 Identities = 130/476 (27%), Positives = 187/476 (39%), Gaps = 48/476 (10%)

Query: 905  HEDLIK-LRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTA 963
            H  LI+ LR  L +RLP YMVPA  V LP LP+N NGKLD  AL     DA  +V+    
Sbjct: 3625 HTTLIRRLRDDLGQRLPGYMVPAAFVVLPGLPMNDNGKLDVRAL----PDAEPAVALSAG 3680

Query: 964  VSASTDTERVLCELFEEQLNAVPH--IDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRM 1020
                T  E VLC LF E L  +P    +D+ F  G  S++A  L+ +AR + G  +  R 
Sbjct: 3681 RGPRTPVEEVLCRLFAEVL-GLPRTGAEDNFFDLGGHSLLATRLISRARTELGAELAIRD 3739

Query: 1021 VLTATTIRQLGAAIDAAVDSQDAPADADYGAVRP--LPMVS-----WLYE--YGNYRRFT 1071
            +  A T   L      A   Q A    +  A RP  +P+ +     WL E   G+   + 
Sbjct: 3740 LFEAPTPETLA---QRAAAGQPARPVLEPAAQRPARIPLSAAQRRLWLVERITGDGVAYN 3796

Query: 1072 HTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRI 1131
              ++ RL   +D  ++   L+ +   H+ LR+   E    P      P     E  LT  
Sbjct: 3797 FPLVFRLRGTLDLDALRAALRDVTVRHEALRTRFVEADGEPYQWIAAPGEAEPEFRLT-- 3854

Query: 1132 TLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAV 1191
               E  +  +A  +  A R   D +          +     +H      ++ +  HH+  
Sbjct: 3855 ---EADESRIAQWIEEAQRRPFD-LGTELPVRTEVLRLAADDH------VVAVVLHHITT 3904

Query: 1192 DVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQ-DQRDYWAA 1250
            D  S    L DL  A+ +  AG  P   P    Y      +W      +V+ DQ  YW  
Sbjct: 3905 DEWSDRPFLADLHRAYAARAAGAAPDWAPLPVQYAD--HTLWQERLLTEVEDDQLAYWTG 3962

Query: 1251 LVR--EPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATA 1308
             +     +  L L  P   R T     + RA +P   T   L  +     V   +L   A
Sbjct: 3963 ALSGLPAEIPLPLDRPGAPRAT-GRGAVVRATLP-GATGDALRDLAGTHQVSMFMLFQAA 4020

Query: 1309 MAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAA 1364
             A    R     D   G  +A    GR D+ +D    + VG+F N   +R     A
Sbjct: 4021 TAALLHRLGAGDDIPLGAPIA----GRTDSAVD----DLVGFFVNTLVLRTDLSGA 4068



 Score = 93.6 bits (231), Expect = 2e-16
 Identities = 137/479 (28%), Positives = 190/479 (39%), Gaps = 67/479 (13%)

Query: 911  LRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDT 970
            LR    E LP YMVP+  V L  LPV  +GK+D  AL   A D    +S G A    T  
Sbjct: 1094 LRGHAAEWLPDYMVPSAFVPLHALPVTPSGKIDARALP--APD-YAGMSSGRA--PRTPR 1148

Query: 971  ERVLCELFEEQLNA-VPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQ 1029
            E++LC L+ E L       +DD    G DSI AI L+ +AR  GL +  R V    T+  
Sbjct: 1149 EKLLCSLYAEVLGLDSVTAEDDFLALGGDSISAIHLLIRARESGLGLTTREVFRHRTVEA 1208

Query: 1030 LG-AAID-AAVDSQDAP---AD----ADYGAVRPLPMVSWL-------------YEYGNY 1067
            L  AA++  A  + D P   AD    A+     PLP+   L                G+ 
Sbjct: 1209 LAQAAVERVAARTADEPLVEADEAELAELQGAHPLPVDELLPLTPLQQGFFFHALTGGDG 1268

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGP--RLVTREPAAVRAE 1125
              +    +L L   +D S +    Q LLD H  LR+   + P+G   +++TR       E
Sbjct: 1269 DTYVVQQVLDLAGPVDASLLRRAAQQLLDRHSPLRAAFRQRPDGTPVQIITRNAELPWRE 1328

Query: 1126 DVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLT 1185
              L+      G  + L  AVA   R      D +A  ++R    R  E R+     L+LT
Sbjct: 1329 VDLS--AQDGGIRESLGDAVAADER--ARGFDLAAPPLLRCALIRLGEERSR----LVLT 1380

Query: 1186 AHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQR 1245
             HH+  D  S  ++  +L A +     GT    LP    YR +      R +       R
Sbjct: 1381 FHHIVADGWSLPVLHRELMAFY-----GTDAPTLPAVAPYRGFL----RRLAEQDGDAAR 1431

Query: 1246 DYWAALVREPDPALGLRYPDPTR---DTWSTLQLTRAAIPVDVTERV---LGAVRRDQGV 1299
              WA      D   GL   +PTR   D   T  +    + V+++ER    L    R  G+
Sbjct: 1432 AAWA------DALAGL--DEPTRLVGDPADTAPVRPEHVRVELSERTTARLAERARAYGI 1483

Query: 1300 RELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
                +   A  +   R     D   G  V+    GR   V      + VG F N  P R
Sbjct: 1484 TLGTIVQGAWGLLLGRLTGRDDLVFGTTVS----GRDGEV--EGIASMVGLFINTLPTR 1536


>tr|B7T1D2|B7T1D2_9BACT Tax_Id=164851 (teg7)SubName:
            Full=Teg7;[uncultured soil bacterium]
          Length = 4132

 Score =  668 bits (1723), Expect = 0.0
 Identities = 515/1542 (33%), Positives = 742/1542 (48%), Gaps = 125/1542 (8%)

Query: 4    AAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRH 63
            A  +IE++  LSPLQ GL        +G+D+Y   +++D+DGPVD   L  + +A+L RH
Sbjct: 2    AQSRIEEIWPLSPLQAGLLFHAVYDGEGLDVYIGHWILDLDGPVDAARLHAAWEALLTRH 61

Query: 64   PNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDS-------IARSERRRPFDLSR 116
              LRA F  R   + VQI+P    LPW  RV   +  D        +A  +R + FDL+ 
Sbjct: 62   APLRACFRQRKSGETVQIIPRQVELPW--RVVDLSHLDDPEQAVRELAEEDRTKRFDLAN 119

Query: 117  GPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXX 176
             P LR+ ++ +  ++   ++ T HH ++DGWSL +   EL  +                 
Sbjct: 120  APLLRLTLIRLADDS-HCLVVTCHHTIMDGWSLPIVIDELSMLYAANGGPLNLPAVTSYR 178

Query: 177  XYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELL---LPAADTARL 233
             Y+ WL++QD+  AL+ W+  LRG  EP +VA  A  G++ PG  E +   LP   T  L
Sbjct: 179  EYLAWLSRQDKDRALSAWVAELRGAEEPTLVA-PADPGRA-PGMPESVTVELPENLTRSL 236

Query: 234  RQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVP 293
             + A  HGLTLNT V  AWA+VL++L  R +VVFG VVS RP  LPGVE MVGLF+N VP
Sbjct: 237  DELARGHGLTLNTVVRGAWALVLAQLAGRTEVVFGAVVSTRPPDLPGVEGMVGLFLNTVP 296

Query: 294  VVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDA 353
            V   +  +  V+    ++Q++ S +    ++ L++IQ+  G G +FD+L VFE    +  
Sbjct: 297  VRVRLRASTPVLELLAELQKRQSTLIPDQFVGLADIQQAAGPGAIFDTLLVFEKFRREPG 356

Query: 354  IRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERML 413
               +    G Q   ++     HYPLT+V+ +                    A  I ER  
Sbjct: 357  ESDSAETFGIQV--IQGREAAHYPLTLVA-VPGESMLFKLDYLTDLFDQATALAIVERFT 413

Query: 414  TVLRQLPDIGDGTPDDLDIRTAAELKA---HGLLAARSAPTFDTTVWEMFERQVQXXXXX 470
             VLRQL   GD    D+D+ +AAE +        A+ +AP+      ++F RQV+     
Sbjct: 414  GVLRQLTGAGDLRVADVDVTSAAERELVVNEWSAASHAAPS--RLAPDLFGRQVERRRDE 471

Query: 471  XXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXX 530
                       +Y EL  RA +LAG L+  GV     VA+V+ RS               
Sbjct: 472  VAVVDGDRAM-SYGELAERAEKLAGYLSGRGVRRGDRVAVVMDRSPDLIATLLAVWKAGA 530

Query: 531  XYLPVDVTLPSARVESIVRQASPALAI-TEADYSQLVGTAVPTLALDDPAAVESISRRSA 589
             Y+PVD   P  RV+ ++  A PA  +  EA     +   +  + LDDP   ++++  + 
Sbjct: 531  AYVPVDPAYPVERVKFMLADAEPAAVVCAEAYRDAALDGGLDPIVLDDPRTRQAVAECTR 590

Query: 590  AAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXX 649
             +  V    +  AYV++TSGSTG PKGV  ++  V +   +                   
Sbjct: 591  LS--VGATADDLAYVMYTSGSTGTPKGVAVSHGNVAALVGEPG----WAGSPDDAVLMHA 644

Query: 650  XHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQL 709
             HA+ +S    W P   LL G  + L  +  + D + L  G   G +     T   F  +
Sbjct: 645  SHAFDISLFEMWVP---LLSGARVVLAGSGAV-DGEALA-GYVAGGVTAAHLTAGTFRVV 699

Query: 710  ------SAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQ-MAVYNCYGPTEMTVEXXXXX 762
                  S AGL +     +  GG+A+     +++R     + V + YGPTE T+      
Sbjct: 700  AEESPESIAGLRE-----VLTGGDAVPPAAVERVRRTCPGVRVRHLYGPTEATLCATWWL 754

Query: 763  XKDYRKP----TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAA 818
             +   +      IG   +G   YV D+ LR VP GV GELY++GA +A+GY+GR  +TA 
Sbjct: 755  LEPGDETGSVLPIGRPLSGRRVYVLDAFLRPVPPGVAGELYVAGAGVAQGYLGRSALTAE 814

Query: 819  RFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGV 878
            RFVADP  P +RMYRTGDL   +  G  A+ GRAD QVKIRGYRVE GEIE  L G PGV
Sbjct: 815  RFVADPFVPAERMYRTGDLAYWMDQGALAFAGRADDQVKIRGYRVEPGEIEVVLAGLPGV 874

Query: 879  HDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNA 938
              A VS   +     L+G+VV +     D ++LR  L E LP +MVPA ++ L  LP+  
Sbjct: 875  GQAVVSARDEH----LIGYVVAEAGQDVDPVRLRGQLAETLPEFMVPAAVLVLDELPLTV 930

Query: 939  NGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV-PHIDDDLFLFGM 997
            NGK+D  A   L E    S + G     +T+ ER+LC +F E L      ++D  F  G 
Sbjct: 931  NGKVDRQA---LPEPDFASKAVGR--EPATEAERILCGVFAEALGLERVGVEDSFFELGG 985

Query: 998  DSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGA-AIDAAVDSQDAPA-DADYGAVRPL 1055
            DSI ++ +  +ARR+G+ + PR V    T  +L A A +A    +D  A D   G +  +
Sbjct: 986  DSISSMQVAARARREGISLTPRQVFELRTPERLAALAQEAQTTRRDRSAVDTGVGEIPWM 1045

Query: 1056 PMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLR-------SILTET 1108
            P++  L +      F    ++  P+G++  ++   LQ +LD HD LR         L ET
Sbjct: 1046 PVMRALGDDAVRPGFAQARVVVTPAGLNLDALVNALQAVLDVHDLLRVRVEPDGRALFET 1105

Query: 1109 ---------------------PEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAH 1147
                                     RL+  E  AV A  ++TR+    G  DE+A    H
Sbjct: 1106 GRRTGSRQGERYRQQRSAGLSNSARRLIVAERGAVDAAGLVTRVAAGTGKIDEIAE---H 1162

Query: 1148 AARVVTDQIDPSAGAMVRAIWF-RGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAA 1206
             AR    +++PSAG MV+A+W   G   R      L L  HHL+VD VSW I+L DL AA
Sbjct: 1163 EARTAAGRLNPSAGIMVQAVWVDAGNAERGR----LALVVHHLSVDAVSWAILLPDLRAA 1218

Query: 1207 WRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDP 1266
            +  + +G  P + P  TSYR+W   +  +A +     + D W A++   DP+L       
Sbjct: 1219 YDEVISGGTPALEPATTSYRQWARRLTEQAFSESTVAEIDQWIAVLDGADPSLEQHTEQH 1278

Query: 1267 TRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGV 1326
            T  + S        +  ++   + GA     G++E+LLA  A AV  WR        AG+
Sbjct: 1279 TGQSHSWSSTLSGTVARNLVAYLPGAFH--CGIQEVLLAGLAGAVVRWR-----GTDAGL 1331

Query: 1327 LVALEGHGRADAVLDTDTTNTVGWFTNAFPVRL---------GAGAAAVDIEQAERDPVA 1377
            LV +E HGR +A    D   TVGWFT+  PVRL          A   A D   A     A
Sbjct: 1332 LVDVECHGR-EAADGEDLLRTVGWFTSVHPVRLDASGVDLSAAAAGTASDDRSASSATAA 1390

Query: 1378 AQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQFSYLGRLDLGGVADQ 1435
            A  L+ +V   + A+P DGL YGLLRY+  D  A L +   PQI F+YLGR  L    D 
Sbjct: 1391 AGQLLKAVKEQVRAVPGDGLGYGLLRYLNPDTAARLAEWPSPQIGFNYLGRTSL-APTDI 1449

Query: 1436 PWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQL 1477
             W       +   P+   PD  L  A+ +   V  T+ G +L
Sbjct: 1450 AWQ-----QMGEGPLGGGPDTVLAHAVEVGAEVRDTSAGPRL 1486



 Score =  618 bits (1594), Expect = e-174
 Identities = 494/1560 (31%), Positives = 738/1560 (47%), Gaps = 113/1560 (7%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AAAP + D+ +LSPLQEG+       E+GVD+Y  Q ++D+DGP+D E LR + + +  R
Sbjct: 1546 AAAPGLTDIWSLSPLQEGMLFERAFDEEGVDVYQSQRILDLDGPLDAERLRAAWRQLAAR 1605

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWS-------ERVATPAEFDSIARSERRRPFDLS 115
            H +LR +F      + VQ+V     +PW        +     AE D +   ++ R FD+S
Sbjct: 1606 HESLRTSFRQLGSGETVQVVVGEVDIPWRAADVSHLDEADAAAEVDRLLTEDQER-FDVS 1664

Query: 116  RGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXX 175
            + P LR+ ++ + GE + R++ TAHHIL+DGWS  +   E+ A                 
Sbjct: 1665 KAPLLRLSLIRL-GEGRHRLVVTAHHILLDGWSTPIILGEMSAAYAGRLGSSTSPSYRD- 1722

Query: 176  XXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQ 235
              Y+ WL++QD  A  + W   L G  EP MV  +A      P +    L    T  L  
Sbjct: 1723 --YLAWLSRQDEKATRSAWRSELAGSDEPTMVDADAGKTMVMPDEHSEWLSEEATRTLTD 1780

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
            +A  HGLTL+T V   WA+VL+RL  R DVVFGTVVSGRP  +P VE MVG+FIN +PV 
Sbjct: 1781 FARGHGLTLSTIVQGTWALVLARLAGRTDVVFGTVVSGRPADVPDVERMVGMFINTIPVR 1840

Query: 296  HYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIR 355
              + G+  V+     +QR+ SA+ +  Y+ L EIQ+  G G +FD++ +  N P D  + 
Sbjct: 1841 VRLEGSMPVLDMFHDLQRRQSALTEHQYMGLQEIQKAAGTGAIFDTIMMTVNHPRD--VA 1898

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
                  G     +   + T YPL++ S                      A E+  +++ V
Sbjct: 1899 GLGDDGGVAISSIRTRTGTTYPLSM-SATPGERVQIHVAYRPDRIDQETAVEVARQVVRV 1957

Query: 416  LRQL---PDIGDG----TPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXX 468
            + ++   P +  G    T +   +       + G  A  S+      V ++F R+     
Sbjct: 1958 MERVVAEPSLPVGRLGVTSESTRVSVVERWNSTGEAAGGSS------VVDLFRRRSDASP 2011

Query: 469  XXXXXXXXX----------GVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS 518
                               G   +YA+L   + RLAG LA  GV     V +V+ R    
Sbjct: 2012 TVSDDRSASSANAVAVMDAGRTLSYADLDRESDRLAGHLAGLGVRRGHNVGVVMERGADL 2071

Query: 519  XXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDP 578
                         Y+PV+V  P+ R+E ++  A  ++A+        V   V  + +D P
Sbjct: 2072 FVALLAVWKAGAAYVPVNVDYPAERIEWMLADAGVSVAVCAEATRGAVSAGVEPVIVDAP 2131

Query: 579  AAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXX 638
            A +E +      AP++    +  AYV++TSGSTG PKGV   + +V +  +D    +   
Sbjct: 2132 A-IEGVRHE---APSLTVGADDVAYVMYTSGSTGVPKGVAVPHGSVAALASDPGWSL--- 2184

Query: 639  XXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDM 698
                        HA+  S    W P+V    G  + + +   + DA RL E IA G +  
Sbjct: 2185 -GTGDCVLMHAPHAFDASLLEIWVPLVS---GARVMVAEPGAV-DAQRLREAIA-GGVTT 2238

Query: 699  IDTTPSMFVQLSAAGLLDHN-LSVLALGGEAINTGLWDQLR-GLSQMAVYNCYGPTEMTV 756
            +  T   F  L+       + L  +  GG+A+      +LR    ++ V + YGPTE+T+
Sbjct: 2239 VHLTAGTFRALAEESPDSFSGLREILTGGDAVPLASVARLRRACPEVRVRHLYGPTEITL 2298

Query: 757  EXXXXXXKDYRKP----TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGR 812
                   +   +      IG   AG   YV D+ L+ V   V GELY+ GA LA GY+G 
Sbjct: 2299 CATWHLLEPSAETGDTLPIGRPLAGRQAYVLDAFLQPVMPNVTGELYIGGAGLAHGYLGT 2358

Query: 813  PGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
             G T+ RF+A+P   G+RMYRTGDL R    G   + GRAD+QVKIRGYRVE  EIE AL
Sbjct: 2359 GGPTSERFIANPFAHGERMYRTGDLARWTGQGELLFAGRADSQVKIRGYRVEPAEIEVAL 2418

Query: 873  RGQPGVHDAAVSVLRQQDRTS---LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIV 929
               P V  A V V  ++DR     L+ +V  + +   D   +R  L  RLP +MVPA +V
Sbjct: 2419 AEVPQVAQAVVVV--REDRPGEKRLIAYVTTEADSGLDPDAVREHLAARLPEFMVPAVVV 2476

Query: 930  TLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHI 988
             L  LP+  NGK+D  A   L     T    G      T+ E VL +LF E L       
Sbjct: 2477 VLDSLPLTVNGKIDRTA---LPAPEFTGKPAGR--EPRTEAELVLVDLFAEILGLDRVGA 2531

Query: 989  DDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADAD 1048
            DD  F  G DSI+++ L  +ARR+ +    + V    T   + A  +   +++    D  
Sbjct: 2532 DDSFFELGGDSILSMQLAARARRRDVVFGAKDVFEQETPAGIAAIAERGGETR-TDLDDG 2590

Query: 1049 YGAVRPLPMVSWLYEY--GNYRR--FTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSI 1104
             G V   P++  L E   G   R      V +  P  +  +++   L  ++D HD LRS 
Sbjct: 2591 VGEVAWTPVMRALLERDPGAMTRGAMAQWVTVGAPDDLSVAALAAGLGAVIDAHDMLRSR 2650

Query: 1105 LTETP-EGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAM 1163
            + ET  + PRLV  +   V A  ++ R+    G  D++A   A+ A V   ++DP+AG M
Sbjct: 2651 IVETEGQEPRLVVADRGGVAAATLVERVEAGAGDVDDIADRCANEAAV---RLDPAAGVM 2707

Query: 1164 VRAIWFRGTEHRADPANI--LLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPE 1221
            + A+W       A P+ +  L++ AHHLAVDVVSW I+L DL  A  ++ AG  P I P 
Sbjct: 2708 ILAVWV-----DAGPSRVGRLVVAAHHLAVDVVSWRILLSDLQVACEAVTAGREPAIGPP 2762

Query: 1222 FTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAI 1281
              S+RRW   +  +A+    + +   W  ++        L   D TRDT ST       +
Sbjct: 2763 DVSFRRWARTLVDQAAIRTAESET--WTEILDGARSQSRLGELDRTRDTISTAGRKSWTV 2820

Query: 1282 PVD----VTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRAD 1337
            P +    + E+V  A     GV E+LLA  A AVA WR          V+V +EGHGR  
Sbjct: 2821 PRNQAGVLVEKVTSAFH--CGVHEVLLATLAGAVAQWR------GGTAVVVDVEGHGR-Q 2871

Query: 1338 AVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGL 1397
             + + D + T+GWFT+  P+RL      VD  +A     AA  L+ +V  ++ A+P+ GL
Sbjct: 2872 PIGEMDLSRTLGWFTDVHPLRL--DVTGVDTAEAIAGGGAAGRLLKNVKENVRAVPDGGL 2929

Query: 1398 DYGLLRYVDGVAELVDAVDP--QIQFSYLGRLDL---GGVADQPWSLLTGPYLDALPIDP 1452
             YG+LR+++       A  P  +I F+YLGR      GGV  +PW +     +  +    
Sbjct: 2930 GYGMLRHLNAETRPALAARPKAEIGFNYLGRFSSRPDGGV--EPWQM-----VGTIGGAA 2982

Query: 1453 EPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD 1512
            E D+PLR  + +   V   A+G +L     W+  +   ++ + L   W   +  LAA +D
Sbjct: 2983 EQDMPLRHVVEIDAAVLDAADGPELTLTVTWAGRILGEAEAESLGKAWLDMLTGLAAHVD 3042



 Score =  459 bits (1180), Expect = e-126
 Identities = 364/1079 (33%), Positives = 505/1079 (46%), Gaps = 75/1079 (6%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            V AA P + D+  LSPLQEGL   H + E G D+Y+    + +DGP+D+   R S Q +L
Sbjct: 3068 VEAAVPNLLDIWPLSPLQEGLL-FHAVDERGPDVYAGMRTLALDGPLDVARFRVSWQTLL 3126

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATP-------AEFDSIARSERRRPFD 113
            DRH  LRA+F        VQ V     LPW E   +        AEF+ +A   +   FD
Sbjct: 3127 DRHDALRASFHQLGSGAAVQAVAREVTLPWLEADLSHLPEDEALAEFERLAEESQADRFD 3186

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            L++ P LR+ ++ + GE + R+I T+HHI  DGWSL VF  E++A               
Sbjct: 3187 LTKAPQLRLHLVRL-GERRHRLILTSHHISADGWSLPVFTVEVMAAYESGGDARALPVPM 3245

Query: 174  XXXXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEAT-AGQSKPGKTELLLPAADTAR 232
                Y+ WLA QD++AA   W   L G+ E   V    T     +P +    L    +  
Sbjct: 3246 SYRDYLTWLAHQDKAAAREAWRTELAGLDEATHVVPPVTITAPIEPDRVRFELDDDLSRH 3305

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            + ++  RHG+T+NT     WA++L+RLT R DVVFGT V+GRP ++PGVE+ VGLF+N +
Sbjct: 3306 MVEFTRRHGVTMNTLFQGVWALLLARLTGRDDVVFGTTVAGRPPEIPGVESAVGLFMNML 3365

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDD 352
            PV   ++G E  +     +Q +  A+    ++ L+EI    G G  FD++ VFEN P   
Sbjct: 3366 PVRARLTGAEPFLDMLADLQERQVALMPHQHVGLTEINHFAGPGAAFDTIVVFENYPSPP 3425

Query: 353  AIRPATTPDGAQFLPVEMESLT-HYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGER 411
               P+  PD     P  +   T HYPL+    +R                     ++ E 
Sbjct: 3426 P--PSEDPDVLAVRPAGIPDDTGHYPLS----MRASEGGGVHGEVIFRPDAFDRTQVEEI 3479

Query: 412  MLTVLRQLPDI-----------GDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMF 460
            + +++R L  +           G   P+ L +      +    L   + P        +F
Sbjct: 3480 VASIIRALEQVVADPRMPVGRVGLIGPEQLRLVVEEWNQTDVPLVPEALPV-------LF 3532

Query: 461  ERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXX 520
             RQV                 ++  L      LA  L   GV  ET V +V+ RS     
Sbjct: 3533 RRQVARSRDAVAVVDAARSL-SFGGLLDEVEALARLLVGLGVRRETRVGVVVERSAELAV 3591

Query: 521  XXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGT--AVPTLALDDP 578
                       ++PVD+  P+ R+E I+  ++PA+ +  A    +V    A   + LD+ 
Sbjct: 3592 TLMGVSFAGGVFVPVDLDYPAERIELILANSAPAVLVCTAATRAVVPEKFAGAVVVLDEL 3651

Query: 579  AAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXX 638
             A +         P V   P   AYVI+TSGSTG PKGVV T++ + +    H ER+   
Sbjct: 3652 PAADP----EVVLPPV--APGDGAYVIYTSGSTGVPKGVVVTHSGLGNLARAHIERMAVT 3705

Query: 639  XXXXXXXXXXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQID 697
                           ++ FDA    + + LL G  + L DAE M     L + I    I 
Sbjct: 3706 SSSRVLQLS------AIGFDAIVSELYMALLAGGTLVLADAESMPPRVTLGDTIRRWGIT 3759

Query: 698  MIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV- 756
             +  +PS+   L+    L  +L  +  GGE +   L D+     +M   N YGPTE T+ 
Sbjct: 3760 HVTVSPSV---LAVEDDLPDSLETVLTGGEVLPPALVDRWSPGRRMI--NAYGPTETTIC 3814

Query: 757  -EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGM 815
                      +    +G        YV DS L+ VP GV GELY++G  LARGY+GRPG+
Sbjct: 3815 STMSFPLSPGHDVVPLGGPIDNVRHYVLDSFLQPVPPGVAGELYITGVGLARGYLGRPGL 3874

Query: 816  TAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQ 875
            TA RFVADP  PG RMYR+GD  R    G   +VGRAD QVK+RGYRVE  EIEA L   
Sbjct: 3875 TAERFVADPFSPGGRMYRSGDRFRWTREGELVFVGRADAQVKVRGYRVEPAEIEAVLAEH 3934

Query: 876  PGVHDAAVSVLRQQ-DRTSLVGFVVWQDNMHED----LIKLRAGLTERLPSYMVPARIVT 930
            P V   AV+V R +     LV +VV   N   +    +  LR    ERLP YM+PA  V+
Sbjct: 3935 PAVAQVAVAVRRDRPGEKQLVAYVVPAANAPAEGGALVSALRELAAERLPEYMMPAAFVS 3994

Query: 931  LPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHID 989
            L R+P+  NGKLD  AL   A D     SG       T  E  LCELF E L       D
Sbjct: 3995 LDRMPLTPNGKLDHRALQ--APDFAGMSSGR---DPRTAMEARLCELFAEVLGLDRAGAD 4049

Query: 990  DDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADAD 1048
            D  F  G DSI ++ L  +ARR+GL +    V    T  +L      AV  ++ PAD D
Sbjct: 4050 DSFFELGGDSITSMQLSARARRKGLDLTSWRVFDEKTPERL------AVLVKELPADGD 4102



 Score = 49.7 bits (117), Expect = 0.003
 Identities = 76/285 (26%), Positives = 112/285 (39%), Gaps = 25/285 (8%)

Query: 1076 LRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRL--VTREPAAVRAEDVLTRITL 1133
            L L   +D +   +  Q LLD HD LR+   +   G  +  V RE      E  L+   L
Sbjct: 3107 LALDGPLDVARFRVSWQTLLDRHDALRASFHQLGSGAAVQAVAREVTLPWLEADLSH--L 3164

Query: 1134 PEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDV 1193
            PE  D+ LA     A     D+ D +    +R    R  E R    + L+LT+HH++ D 
Sbjct: 3165 PE--DEALAEFERLAEESQADRFDLTKAPQLRLHLVRLGERR----HRLILTSHHISADG 3218

Query: 1194 VSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVR 1253
             S  +   ++ AA+ S   G   + LP   SYR +   + H+  A      R+ W   + 
Sbjct: 3219 WSLPVFTVEVMAAYES---GGDARALPVPMSYRDYLTWLAHQDKAA----AREAWRTELA 3271

Query: 1254 EPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVAS 1313
              D A  +  P  T          R  +  D++  ++   RR  GV    L     A+  
Sbjct: 3272 GLDEATHV-VPPVTITAPIEPDRVRFELDDDLSRHMVEFTRR-HGVTMNTLFQGVWALLL 3329

Query: 1314 WRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
             R     D   G  VA    GR   +   +  + VG F N  PVR
Sbjct: 3330 ARLTGRDDVVFGTTVA----GRPPEIPGVE--SAVGLFMNMLPVR 3368


>tr|O52820|O52820_AMYOR Tax_Id=31958 SubName:
            Full=PCZA363.4;[Amycolatopsis orientalis]
          Length = 4077

 Score =  667 bits (1721), Expect = 0.0
 Identities = 520/1531 (33%), Positives = 750/1531 (48%), Gaps = 90/1531 (5%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            +IE++  LSPLQ GL        +G D+Y   +++D+DGPVD   LR + + +L RH  L
Sbjct: 5    RIEEIWPLSPLQAGLLFHAVYDGEGPDVYIGHWILDLDGPVDAARLRAAWETLLTRHAPL 64

Query: 67   RAAFWDRDVPKPVQIVPVHAALPWSE----RVATPAE-FDSIARSERRRPFDLSRGPALR 121
            RA F  R   + VQI+     LPW E     +  P +    +A  +R   FDL++ P LR
Sbjct: 65   RACFRQRKSGETVQIIARQVELPWREVDLSHLDDPEQAVRELAEQDRTTRFDLTQAPLLR 124

Query: 122  VVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVW 181
            + ++ +  + K R++ T HH ++DGWSL +   EL  +                  Y+ W
Sbjct: 125  LTLIRLDDD-KFRLVVTCHHTIMDGWSLPIVIDELSMLYPAGDAPAALPEVTSYREYLAW 183

Query: 182  LAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQS--KPGKTELLLPAADTARLRQWAGR 239
            L+++D+  AL+ W   LRGV EP +VA  A  G++  +P   E+ LP   T  L + A  
Sbjct: 184  LSRRDKERALSAWAAELRGVEEPTLVA-PADPGRAPAEPESVEVDLPENLTRSLAELARG 242

Query: 240  HGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVS 299
            HGLTLNT V  AWA+VL++L+ R DVVFG  VS RP  LPGVE MVGLF+N VPV   + 
Sbjct: 243  HGLTLNTVVQGAWALVLAQLSGRTDVVFGAAVSARPPDLPGVEGMVGLFLNTVPVRVRLR 302

Query: 300  GTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATT 359
            G+  V+    ++Q++ SA+    ++ L++IQ+  G   +FD+L VFE      A      
Sbjct: 303  GSMPVIELLAELQKRQSALIPDQFVGLADIQQVAGPAAVFDTLLVFEKFHHGPA-----G 357

Query: 360  PDGAQFLPVEMES---LTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVL 416
             D AQ   +++       HYPLT+V+ +                    A  I ER   VL
Sbjct: 358  SDSAQTFGIQVNQGRVAAHYPLTLVA-VPGESMYVKLDYLTDLFDQDTALAIVERFTGVL 416

Query: 417  RQLPDIGDGTPDDLDIRTAAELK-AHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXX 475
            RQL D GD T  D+D+ +AAE         A S  T      ++F  QV+          
Sbjct: 417  RQLTDAGDLTVADVDVTSAAERALVVDEWGAASQATPSMLALDLFGSQVKDRRDEVAVVD 476

Query: 476  XXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPV 535
                  +Y EL   A RLAG L   GV     VA+VL RS                Y+PV
Sbjct: 477  GDRAM-SYGELAEHAERLAGYLNGRGVRRGDRVAVVLDRSLDLIATLLAVWQAGAAYVPV 535

Query: 536  DVTLPSARVESIVRQASPALAI-TEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTV 594
            D   P  R++ ++  + PA  +  EA    ++   +  ++LDDP   ++++  +AA  +V
Sbjct: 536  DPAYPVERMKFMLADSEPAAVVCAEAYRDAVLDVGLDPISLDDPQTRQAVA--AAARISV 593

Query: 595  DRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWS 654
              +    AYV++TSGSTG PKGV  ++  V +   +    V               HA+ 
Sbjct: 594  GTKANDLAYVMYTSGSTGTPKGVAVSHGNVAALVGEPGWGV----GPDDAVLMHASHAFD 649

Query: 655  LSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQL----- 709
            +S    W P   LL G  + L  +  + D + L  G   G +     T   F  L     
Sbjct: 650  ISLFEMWVP---LLSGARLVLAGSGAV-DGEALA-GYVAGGVTAAHLTAGAFRVLADESP 704

Query: 710  -SAAGLLDHNLSVLALGGEAINTGLWDQLRGLS-QMAVYNCYGPTEMTVEXXXXXXKDYR 767
             S  GL +     +  GG+A+     +++R     + V + YGPTE T+       +   
Sbjct: 705  ESVVGLRE-----VLTGGDAVPLAAVERVRRTCPDVRVRHLYGPTEATLCATWWLLEPGD 759

Query: 768  KP----TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVAD 823
            +      IG   AG   YV D+ LR VP GV GELY++GA +A+GY+GR  +TA RFVAD
Sbjct: 760  ETGSVLPIGRPLAGRRVYVLDAFLRPVPPGVAGELYIAGAGVAQGYLGRSALTAERFVAD 819

Query: 824  PLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAV 883
            P     RMYRTGDL      G  A+ GRAD QVKIRGYRVE GEIE  L G PGV  A V
Sbjct: 820  PFVAAGRMYRTGDLAYWTHQGALAFAGRADDQVKIRGYRVEPGEIEVVLAGLPGVGQAVV 879

Query: 884  SVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLD 943
            SV  +     L+G+VV +     D  +LR  L E LP +MVPA ++ L  LP+  NGK+D
Sbjct: 880  SVRDEH----LIGYVVAEAGQAIDPARLREQLAETLPEFMVPAAVLVLDELPLTVNGKVD 935

Query: 944  GHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSIVA 1002
              A   L E    S S G      T+ ERVLC +F E L      I+D  F  G DSI +
Sbjct: 936  RRA---LPEPDFASKSAGR--EPVTEAERVLCGVFAEVLGLDRVGIEDSFFELGGDSISS 990

Query: 1003 ISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLY 1062
            + +  +ARR+G+ + PR V    T  +L A    A  +  A      G +   P++  L 
Sbjct: 991  MQVAARARREGISLTPRQVFEHRTPERLAALAQEASTTPRAEVVTGVGEIPWTPVMRALG 1050

Query: 1063 EYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAV 1122
            +      F    ++  P+G++  ++   LQ +LDGHD LR+ +   P+G RL+  E  AV
Sbjct: 1051 DDAMRPGFVQVRVVVTPAGLNLDALVSALQAVLDGHDLLRARV--EPDG-RLIVPERGAV 1107

Query: 1123 RAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANIL 1182
             A  ++TR+ +  G  DE+A       R  T  ++PSAG M R +W    +  A+P   L
Sbjct: 1108 DATGLVTRVAVGTGDLDEIAE---REVRTATGTLNPSAGIMARLVWIDAGD--AEPGR-L 1161

Query: 1183 LLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQ 1242
               AHHL+VD VSW I+L DL  A+  + +G  P + P  TSYR+W   +  +A +    
Sbjct: 1162 AFVAHHLSVDAVSWGILLPDLQTAYDEVISGGTPALEPPTTSYRQWARRLTEQALSESTV 1221

Query: 1243 DQRDYWAALVREPDPALGLRYPDPT--RDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVR 1300
             + D W A++   +P L       T    +WST +L+   +  ++   + GA     G++
Sbjct: 1222 AELDQWVAVLDGANPPLEQDTGQHTGQSHSWST-RLSGTEVR-NLVAHLPGAFH--CGIQ 1277

Query: 1301 ELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLG 1360
            ++LLA  A AVA     R +   AG+LV +EGHGR +A    D   TVGWFT+  PVRL 
Sbjct: 1278 DVLLAGLAGAVA-----RVRGTGAGLLVDVEGHGR-EAADGEDLLRTVGWFTSVHPVRL- 1330

Query: 1361 AGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQ 1418
               + VD+  A      A  L+ +V   + A+P DG  YGLLR++  D  A L +    Q
Sbjct: 1331 -DLSDVDLAAAAAGNAPAGQLLKAVKEQIRAVPGDGSGYGLLRHLNPDTGARLAELPSAQ 1389

Query: 1419 IQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLI 1478
            I F+YLGR  L    +  W     P  +  P+   PD+ L  A+ +S  +  T  G +L 
Sbjct: 1390 IGFNYLGRTVL-AAQNTAWQ---QPVAEG-PLGGGPDMVLAHAVEVSAELLDTPAGPRL- 1443

Query: 1479 GNWRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
                     F+ + ++ L   W   +  LAA
Sbjct: 1444 -GLAIDTRDFDLATVERLGEAWLEMLTGLAA 1473



 Score =  608 bits (1567), Expect = e-171
 Identities = 490/1547 (31%), Positives = 723/1547 (46%), Gaps = 99/1547 (6%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AAAP + D+  LSPLQEG+       EDGVD+Y  Q ++D+DGP+D + LR +   ++ R
Sbjct: 1503 AAAPGLTDIWPLSPLQEGMLFERAFDEDGVDVYQTQRILDLDGPLDAQRLRTAWNQVVAR 1562

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWS-------ERVATPAEFDSIARSERRRPFDLS 115
            H +LR +F      + VQ+V   A +PW        +     AE + +   ++   FD++
Sbjct: 1563 HESLRTSFHQLGSGETVQVVAREADIPWRVADLSHLDEAEAAAEVERLLAQDQAERFDVA 1622

Query: 116  RGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXX 175
              P LR++++ + G  K +++ T+HH+LVDGWS  +   E+ A                 
Sbjct: 1623 TAPLLRLLLIRL-GADKHKLVMTSHHLLVDGWSTPLIVGEMSA---GYAGGPSASKSPSY 1678

Query: 176  XXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQ 235
              Y+ WL++QD     + W   L G  EP +V  +A      P     LL  A T  L  
Sbjct: 1679 KDYLAWLSRQDEETTRSAWRSELAGCDEPTLVDADAGKTLVMPDNRSELLSEATTRTLAD 1738

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
            +A  HGLTL+T VL AWA+VL+RL  R DVVFG+VVSGRP  +P VE MVG+FIN VP  
Sbjct: 1739 FARGHGLTLSTVVLGAWALVLARLAGRTDVVFGSVVSGRPADVPDVERMVGMFINTVPAR 1798

Query: 296  HYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIR 355
              + G + VV     +Q + SA+ +  Y+ L EIQ+  G G +FD++ + EN P   A  
Sbjct: 1799 VRLDGRQPVVEMLKDLQGRQSALTEHQYMGLPEIQKVAGTGAIFDTIVMIENYPHTAA-- 1856

Query: 356  PATTPDGAQFLP-VEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLT 414
                 DG   +  V   + T YPLT+   L                    A E+  +++ 
Sbjct: 1857 -GLGDDGGVVISSVATRTGTSYPLTMNVSLGERLRVNVSYRPDRIDDET-ATEVARQVVR 1914

Query: 415  VLRQL---PDIGDG----TPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXX 467
            VL Q+   P +  G    T +           + G  A R      T+V E+F +Q    
Sbjct: 1915 VLEQVVAQPLLPVGRLGVTSEPARASVVERWNSTGEAANR------TSVLELFRQQADAS 1968

Query: 468  XXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXX 527
                          +YA+L   + RLAG LA  GV     V +V+ R             
Sbjct: 1969 PDAVAVMDAARTL-SYADLDRESDRLAGYLAAMGVRRGDRVGVVMERGTDLFVALLAVWK 2027

Query: 528  XXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRR 587
                 +PV+V  P+ R+E ++  A  ++A+      + V   V  + +D PA ++ +   
Sbjct: 2028 AGAAQVPVNVDYPAERIERMLADAGASVAVCLEATRKAVPDGVEPVVMDVPA-IDGVRHE 2086

Query: 588  SAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXX 647
               AP V       AYV++TSGSTG PKGV   + +V +  +D                 
Sbjct: 2087 ---APQVTVGAHDLAYVMYTSGSTGVPKGVAVPHGSVAALASDPG----WSQGPDDCVLL 2139

Query: 648  XXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFV 707
               HA+  S    W P+V   +G  + + +   + DA+RL E I+ G   +  T  +   
Sbjct: 2140 HASHAFDASLVEIWVPLV---NGSRVMVAEPGAV-DAERLREAISRGVTTVHLTAGAFRA 2195

Query: 708  QLSAAGLLDHNLSVLALGGEAINTGLWDQLR-GLSQMAVYNCYGPTEMTVEXXXXXXKDY 766
                +      L  +  GG+A+      ++R     + V   YGPTE+T+       +  
Sbjct: 2196 VAEESPDSFTGLREILTGGDAVPLASVVRMRRACPDVRVRQLYGPTEITLCATWHVIEPG 2255

Query: 767  RKP----TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVA 822
             +      IG   AG   YV D+ L+ V   V GELY++GA LA GY+G  G T+ RF+A
Sbjct: 2256 AETGDTLPIGRPLAGRQAYVLDAFLQPVAPNVTGELYIAGAGLAHGYLGNNGSTSERFIA 2315

Query: 823  DPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAA 882
            +P   G+RMYRTGDL R    G   + GRAD+QVKIRGYRVE GEIE AL   P  H A 
Sbjct: 2316 NPFASGERMYRTGDLARWTDQGELLFAGRADSQVKIRGYRVEPGEIEVALTEVP--HVAQ 2373

Query: 883  VSVLRQQDRTS---LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNAN 939
              V+ ++D      L+ +V  ++        +R  L  R+P +MVPA ++ L   P+  N
Sbjct: 2374 AVVVAREDHPGDKRLIAYVTAEEGPALAADAVREHLAARMPEFMVPAVVLVLDSFPLTLN 2433

Query: 940  GKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMD 998
            GK+D  A   L     T  + G      T+TERVLC+LF E L       DD  F  G D
Sbjct: 2434 GKIDRAA---LPAPEFTGKAAGR--EPRTETERVLCDLFAEILGLDRVGADDSFFELGGD 2488

Query: 999  SIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMV 1058
            SI+++ L  +ARR+      + V    T   + A  +    ++   A+   G V   P+V
Sbjct: 2489 SILSMRLAARARRENFVFGAKQVFEQKTPAGIAAVAERGGQARVEDAEG-VGEVPWTPVV 2547

Query: 1059 SWLYE---YGNYR-RFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEG--P 1112
              + E    G  R      V + +P  +  +++   L  ++D HD LRS + +T EG  P
Sbjct: 2548 RAMLERDPIGLTRGAMAQWVTVDVPDDLSVTALAAGLGAVIDTHDMLRSRIVDT-EGAEP 2606

Query: 1113 RLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGT 1172
            RLV      V A  ++ R+       DE+A   A+ A     ++DP AG MVRA+W    
Sbjct: 2607 RLVVAGRGTVDASTLVERVEAGADDVDEIADRCANDAAA---RLDPVAGVMVRAVWVDAG 2663

Query: 1173 EHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELM 1232
              R   A  L++ AHHL VDVVSW  +L DL AA  ++ AG  P + P   S+RRW   +
Sbjct: 2664 PGR---AGRLVVAAHHLVVDVVSWRTLLPDLQAACEAVAAGLRPALDPPDVSFRRWARTL 2720

Query: 1233 WHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVD----VTER 1288
               A+      +   W  ++      LG    DP RDT ST       +P      + E+
Sbjct: 2721 ADEAAIRTA--ELATWTDILDGARSRLG--ELDPKRDTVSTAGRKSWTVPQKHAGVLVEK 2776

Query: 1289 VLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTV 1348
            V  A     GV E+LLA  A AVASWR          V+V +EGHGR   + + D + T+
Sbjct: 2777 VTSAFH--CGVHEVLLATLAGAVASWR------GGTDVVVDVEGHGR-QPIGEMDLSRTL 2827

Query: 1349 GWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGV 1408
            GWFT+  P+RL      VD  +A     AA  L+  V  ++ A+P+ GL YG+LRY++  
Sbjct: 2828 GWFTDVHPLRL--DVTGVDTAEAIAGGGAAGRLLKQVKENVRAVPDGGLGYGMLRYLNAE 2885

Query: 1409 AELVDAVDP--QIQFSYLGRLDLGGVAD-QPWSLLTGPYLDALPIDPEPDLPLRFALNLS 1465
               V A  P  +I F+YLGR       + QPW +        +    E D PLR  + + 
Sbjct: 2886 TGPVLAALPKAEIGFNYLGRFSSRPDGEAQPWQI-----KGIVGGAAEQDTPLRHVVEID 2940

Query: 1466 VFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD 1512
              V   A+G +      W+  +   ++ +     W   ++ LAA ++
Sbjct: 2941 AVVLDGADGPEFTLTVTWAGRIVGDAEAESFANAWLDMLSGLAAHVE 2987



 Score =  460 bits (1183), Expect = e-127
 Identities = 351/1070 (32%), Positives = 504/1070 (47%), Gaps = 78/1070 (7%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            + AA P + D+  LSPLQEGL   H   E G D+Y+    + +DGP+D++  R S Q +L
Sbjct: 3012 IEAAVPNLLDIWPLSPLQEGLL-FHAADEGGPDVYASMRTLVLDGPLDVDRFRASWQTLL 3070

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATP-------AEFDSIARSERRRPFD 113
            DRH  LRA+F   +    VQ +     LPW E   +        AEFD +A       FD
Sbjct: 3071 DRHAALRASFHQVESGTAVQAIAREVTLPWRETDLSHLPEDEAVAEFDRLAAELLAERFD 3130

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
             ++ P LR+ ++   GE + R+IFT+HHI  DGWSL +   ++LA               
Sbjct: 3131 PTQAPLLRLHLVRF-GEREHRLIFTSHHIAADGWSLPLIGVDVLAAYEAGGDGRTLPAAT 3189

Query: 174  XXXXYIVWLAKQDRSAALAGWMDYLRGVSEPL-MVAYEATAGQSKPGKTELLLPAADTAR 232
                Y+ W+A+QD++AA   W   L G+ E   +V  E+      P +    L    + R
Sbjct: 3190 SYRDYLAWIARQDKTAAREAWRTELAGLEEATNVVPPESIRTPLVPERVRFELGDEPSRR 3249

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L ++A RHG+T NT     WA+ L+RLT R+DVVFG  V+GRP ++PGVE+ VGLF+N +
Sbjct: 3250 LVEFARRHGVTPNTLFQGVWALHLARLTGRQDVVFGAAVAGRPPEIPGVESSVGLFMNML 3309

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPID- 351
            PV   ++G + VV     +Q +  A+    ++ LSEI++  G G  FD++ VFEN P   
Sbjct: 3310 PVRARLTGAQPVVDMLKDLQERQIALMSHQHIGLSEIKQFAGPGAAFDTIVVFENYPPPP 3369

Query: 352  ------DAI--RPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYL 403
                  DA+  RPA TP+             HYPL++ + +                   
Sbjct: 3370 PRFDGPDALVMRPAGTPNDTG----------HYPLSIRASVAAGPVQGEFIYRPDVVDRA 3419

Query: 404  PAAEIGERMLTVLRQL--------PDIGDGTPDDLDIRTAAELKAHGLLAARSAPT-FDT 454
             A E+   +L  L Q+          +G   P    +      +    LAA + P  F  
Sbjct: 3420 EAEEMVAALLRALEQVLADPRMPVGQVGLIGPQQRRLVVDEWNQTDAPLAAETLPVLFRE 3479

Query: 455  TVWEMFERQVQXXXXXXXXXXXXGVRH-TYAELHARACRLAGELAEHGVGPETVVALVLP 513
              W+  +                GVR  +++ L      LA  L   GV  E  V +++ 
Sbjct: 3480 QAWQSPDAVA----------VQDGVRSLSFSGLLDEVEALARLLVGLGVRREARVGVLVE 3529

Query: 514  RSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTL 573
            RS                ++PVD   PS R+E ++  ++P + +     ++     VP  
Sbjct: 3530 RSVELAVTLMGVSFAGGVFVPVDPDYPSERIEFMLANSAPEVLVC----TKTTRAVVPAQ 3585

Query: 574  ALDDPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAE 633
                   ++ +          D  PE +AYVI+TSGSTG PKGV+ T++ +++    H E
Sbjct: 3586 FTGTVLVLDELPAADPGVELPDVAPEDAAYVIYTSGSTGVPKGVLVTHSGLVNLGYAHIE 3645

Query: 634  RVYXXXXXXXXXXXXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIA 692
            R+                  ++ FDA    + + LL G  + L D+  M     L + I 
Sbjct: 3646 RMAVTSSSRVLQLS------AIGFDAIVSELYMALLAGATLVLPDSANMPPRVTLGDAIR 3699

Query: 693  IGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPT 752
               I  +  +PS+   L++   L   L  +  GGEA+   L D  R      V   YGPT
Sbjct: 3700 KAGITHLTVSPSV---LASEDDLPDTLQTVLTGGEALPAALVD--RWSPGRRVIQAYGPT 3754

Query: 753  EMTV--EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYV 810
            E T+           + +  +G        YV D+ L+ VP GVVGELY++G  LARGY+
Sbjct: 3755 ETTICSTMSAPLSPGHDQVPLGGPIYNVRHYVLDAFLQPVPPGVVGELYITGVGLARGYL 3814

Query: 811  GRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEA 870
            GRPG+TA RFVA P  PG+RMYR+GDL R    G   + GR D QVK+RGYRVE  EIEA
Sbjct: 3815 GRPGLTAERFVASPFAPGERMYRSGDLFRWTREGQLMFAGRVDAQVKVRGYRVEPAEIEA 3874

Query: 871  ALRGQPGVHDAAVSVLRQ-QDRTSLVGFVVWQDNMHEDLIKLRAGL----TERLPSYMVP 925
             L   PGV   AV+V R       LV +VV   +   +   L + L     ERLP YM+P
Sbjct: 3875 VLIEHPGVAQVAVAVRRDGPGDKQLVAYVVPSADAAGENGTLTSALRELAAERLPEYMMP 3934

Query: 926  ARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV 985
            A  V+L ++P+  NGKLD  AL      A    +  T    ST  E  LCELF + L   
Sbjct: 3935 AAFVSLEKMPLTPNGKLDHKAL-----QAPDFAAMSTKRDPSTPMEARLCELFADVLGLE 3989

Query: 986  P-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAI 1034
               +DD  F  G DSI ++ L  +ARR+GL + P  V    T  +L A +
Sbjct: 3990 QVGVDDSFFELGGDSITSMQLSARARREGLELTPWQVFDEKTPERLAAMV 4039



 Score = 59.3 bits (142), Expect = 4e-06
 Identities = 86/331 (25%), Positives = 138/331 (41%), Gaps = 34/331 (10%)

Query: 1073 TVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRL--VTREPAAVRAEDVLTR 1130
            T++L  P  +DR       Q LLD H  LR+   +   G  +  + RE      E  L+ 
Sbjct: 3050 TLVLDGPLDVDR--FRASWQTLLDRHAALRASFHQVESGTAVQAIAREVTLPWRETDLSH 3107

Query: 1131 ITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRA--IWFRGTEHRADPANILLLTAHH 1188
              LPE  D+ +A     AA ++ ++ DP+   ++R   + F   EHR      L+ T+HH
Sbjct: 3108 --LPE--DEAVAEFDRLAAELLAERFDPTQAPLLRLHLVRFGEREHR------LIFTSHH 3157

Query: 1189 LAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYW 1248
            +A D  S  ++  D+ AA+   +AG   + LP  TSYR +  L W   +       R+ W
Sbjct: 3158 IAADGWSLPLIGVDVLAAY---EAGGDGRTLPAATSYRDY--LAW--IARQDKTAAREAW 3210

Query: 1249 AALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATA 1308
               +   + A  +  P+  R T    +  R  +  + + R++   RR  GV    L    
Sbjct: 3211 RTELAGLEEATNVVPPESIR-TPLVPERVRFELGDEPSRRLVEFARR-HGVTPNTLFQGV 3268

Query: 1309 MAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR---LGAGAAA 1365
             A+   R    QD   G  VA    GR   +   +  ++VG F N  PVR    GA    
Sbjct: 3269 WALHLARLTGRQDVVFGAAVA----GRPPEIPGVE--SSVGLFMNMLPVRARLTGAQPVV 3322

Query: 1366 VDIEQAERDPVAAQDLVHSVVSHLEAIPNDG 1396
              ++  +   +A     H  +S ++     G
Sbjct: 3323 DMLKDLQERQIALMSHQHIGLSEIKQFAGPG 3353


>tr|Q939Z0|Q939Z0_9PSEU Tax_Id=208443 (bpsB)SubName: Full=Peptide
            synthetase;[Amycolatopsis balhimycina]
          Length = 4077

 Score =  659 bits (1699), Expect = 0.0
 Identities = 522/1542 (33%), Positives = 745/1542 (48%), Gaps = 108/1542 (7%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            +IE++  LSPLQ GL        +G D+Y   +++D+ GPVD   LR + + +L RH  L
Sbjct: 5    RIEEIWPLSPLQAGLLFHAVYDGEGPDVYIGHWILDLAGPVDAAGLRAAWETLLARHAPL 64

Query: 67   RAAFWDRDVPKPVQIVPVHAALPWSE----RVATPAE-FDSIARSERRRPFDLSRGPALR 121
            RA F  R   + VQI+     LPW E     +  P E    +A  +R   FDL++ P LR
Sbjct: 65   RACFRQRKSGETVQIIARQVELPWREVDLSHLDDPEEAVRELAEQDRTTRFDLAQAPLLR 124

Query: 122  VVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVW 181
            + ++ + G    R++ T HH ++DGWSL +   EL  +                  Y+ W
Sbjct: 125  LTLIRL-GADAHRLVVTCHHTIMDGWSLPIVIDELSVLYPAGGDASALPDVPSYREYLAW 183

Query: 182  LAKQDRSAALAGWMDYLRGVSEP-LMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRH 240
            L++QD+  AL+ W   L G  EP L+V  +     ++P   E  LP   T  L + A RH
Sbjct: 184  LSRQDKERALSAWTAELSGAEEPTLVVPADPGRAPAEPESVEAHLPEHLTRSLAELARRH 243

Query: 241  GLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSG 300
            GLTLNT V  AWA+VL++L  R DVVFG  VS RP  LPGVE MVGLF+N VPV   + G
Sbjct: 244  GLTLNTVVQGAWALVLAQLAGRPDVVFGAAVSARPPDLPGVEGMVGLFLNTVPVRVRLRG 303

Query: 301  TEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTP 360
            +  VV    ++Q++ SA+    ++ L++IQ+  G   +FD+L VFE      A       
Sbjct: 304  STPVVELLAELQKRQSALIPDQFVGLADIQQAAGPAAVFDTLLVFEKFHHGPA-----GS 358

Query: 361  DGAQFLPVEMES---LTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLR 417
            D A    + +       HYPLT+V+ +                    A  I ER   VLR
Sbjct: 359  DSAGTFRIHVNQGRVAAHYPLTLVA-VPGESMYLKLDYLTELFDRETAFAILERFTGVLR 417

Query: 418  QLPDIGDGTPDDLDIRTAAE--LKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXX 475
            QL   G+ T   +++ TAAE  L A    A+ SAP       ++F  QV           
Sbjct: 418  QLTGAGELTVAGVEVTTAAERALVAGEWGASTSAPP-SLPALDLFGHQVAHRRDEPAVVD 476

Query: 476  XXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPV 535
                  +Y EL  RA RLAG L   GV     VA+VL RS                Y+PV
Sbjct: 477  GDRTV-SYGELAERAERLAGYLNGRGVRRGDRVAVVLDRSPDLIATLLAVWKAGAAYVPV 535

Query: 536  DVTLPSARVESIVRQASPALAITEADYSQLVGTAVPT-LALDDPAAVESI--SRRSAAAP 592
            D   P  R + ++  + PA  +    Y   V    P  + LDDP   +++  S R +A  
Sbjct: 536  DPAYPVERRKFMLADSGPAAVVCAEAYRAAVPDTCPEPIVLDDPRTRQAVAESPRLSAGT 595

Query: 593  TVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHA 652
            + D      AYV++TSGSTG PKGV  ++  V +   +   RV               HA
Sbjct: 596  SAD----DLAYVMYTSGSTGTPKGVAVSHGNVAALAGEPGWRV----GPGDAVLLHASHA 647

Query: 653  WSLSFDASWQPMV----------GLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTT 702
            + +S    W P++          G +DG  +  + A  +  A        +    + D +
Sbjct: 648  FDISLFEMWVPLLSGARVVLAGPGAVDGAALAAYVAGGVTAAHLTAGAFRV----LADES 703

Query: 703  PSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRG-LSQMAVYNCYGPTEMTVEXXXX 761
            P      + AGL +     +  GG+A+     +++RG +  + V + YGPTE T+     
Sbjct: 704  PE-----AVAGLRE-----VLTGGDAVPLAAVERVRGRVRNVRVRHLYGPTEATLCATWW 753

Query: 762  XXKDYRKP----TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTA 817
              +   +      IG   AG   +V D+ LR VP GV GELY++GA +A+GY  RP +TA
Sbjct: 754  LLEPGDETGSVLPIGRPLAGRRVHVLDAFLRPVPPGVAGELYVAGAGVAQGYSSRPALTA 813

Query: 818  ARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPG 877
             RFVADP   G RMYRTGDL      G  A+ GRAD QVKIRGYRVE GEIE  L G PG
Sbjct: 814  ERFVADPSGSGARMYRTGDLAYWTEQGALAFAGRADDQVKIRGYRVEPGEIEVVLAGLPG 873

Query: 878  VHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVN 937
            V  A V+   +     L+G+VV +     D ++LR  L   LP +MVPA ++ L  LP+ 
Sbjct: 874  VGQAVVTPRGEH----LIGYVVAEAGHDADPVRLREQLAGTLPEFMVPAAVLVLDELPLT 929

Query: 938  ANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPH--IDDDLFLF 995
             NGK+D  A   L E    + S G      T+ ERVLC +F + L  + H  +DD  F  
Sbjct: 930  VNGKVDRRA---LPEPDFAAKSAGR--EPVTEAERVLCGVFADVL-GLDHVGVDDSFFEL 983

Query: 996  GMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPL 1055
            G DSI ++ +  +ARR+G+ + PR+V    T  +L A    A  +  A      G +   
Sbjct: 984  GGDSISSMQVAARARREGISLTPRLVFEHRTPERLAALAQEAGATPRAEVVTGVGEIPWT 1043

Query: 1056 PMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLV 1115
            P++  L +      F    ++  P+G++  ++   LQ +LD HD LR+ +   P+G RL+
Sbjct: 1044 PVMRALGDDAMRPGFAQVRVVVTPAGVNPDALVSALQAVLDAHDLLRARV--EPDG-RLI 1100

Query: 1116 TREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHR 1175
              E  AV A  +LTR+    G  DE+A       R  T  +DPSAG M R +W    +  
Sbjct: 1101 VPERGAVAAAGLLTRVAAGTGGLDEIAE---REVRTATGTLDPSAGIMARVVWIDAGD-- 1155

Query: 1176 ADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHR 1235
            A+P   L   AHHL+VD VSW I+L DL AA+  + +G  P + P  TSYR+W   +  R
Sbjct: 1156 AEPGR-LAFVAHHLSVDAVSWGILLPDLRAAYDEVISGGTPALEPPVTSYRQWARRLTAR 1214

Query: 1236 ASAPQVQDQRDYWAALVREPDPALGLRYPDPT--RDTWSTLQLTRAAIPVDVTERVLGAV 1293
            A +     + + WAA+V   +PAL       T    +WST  L+   +  D+   + GA 
Sbjct: 1215 ALSESTVAELEKWAAVVEGAEPALPQDTGQHTGQSHSWST-SLSGTEVR-DLVTVLPGAF 1272

Query: 1294 RRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTN 1353
                G++++LLA  A AVA     R +   A +LV +EGHGR +A    D   TVGWFT+
Sbjct: 1273 H--CGIQDVLLAGLAGAVA-----RVRGSGAALLVDVEGHGR-EAADGEDLLRTVGWFTS 1324

Query: 1354 AFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVD--GVAEL 1411
              PVRL    + VD+  A      A  L+ +V   + A+P DG  YGLLR+++    A L
Sbjct: 1325 VHPVRL--ELSDVDLAGAADGERPAGQLLKAVKEQIRAVPGDGSGYGLLRHLNPGTGARL 1382

Query: 1412 VDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVT 1471
             +    QI F+YLGR  L    D  W    G      P+   PD+ L  A+ +S  +  T
Sbjct: 1383 AELPSAQIGFNYLGRTVL-APEDTAWQPNGGG-----PLGGGPDMVLAHAVEVSAELQDT 1436

Query: 1472 AEGTQLIGNWRWSDAVFERSDIDHLTGLWQR---GIAALAAG 1510
              G +L          F+ + ++ L   W     G+AA+A G
Sbjct: 1437 PAGPRL--GLAIDTRDFDLATVERLGEAWLEMLTGLAAVARG 1476



 Score =  603 bits (1556), Expect = e-170
 Identities = 493/1539 (32%), Positives = 707/1539 (45%), Gaps = 88/1539 (5%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AAAP + D+  LSPLQEG+       EDGVD+Y  Q ++D+DGP+D   LR +   +L R
Sbjct: 1502 AAAPGLTDIWPLSPLQEGMLFERAFDEDGVDVYQTQRILDLDGPLDEPRLRAAWNQVLAR 1561

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWS-------ERVATPAEFDSIARSERRRPFDLS 115
            H +LR  F        VQ+V   A +PW        +     AE + +   ++ R FD++
Sbjct: 1562 HASLRTGFHQLGSGATVQVVVREADIPWRVADLSHLDAAEAAAEVERLLAEDQGRRFDVT 1621

Query: 116  RGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXX 175
            R P LR++++ + G  + R++ T+HH+L+DGWS  +   E+                   
Sbjct: 1622 RPPLLRLLLIRL-GADEHRLVVTSHHVLLDGWSTPLVVGEM---SDGYAGGRSSSKPPSY 1677

Query: 176  XXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQ 235
              Y+ WL++QD  A  + W   L G  EP +V  +A      P +    LP   T  L  
Sbjct: 1678 QDYLAWLSRQDAEATRSAWRAELAGADEPTLVDADAGKTLVMPDEHAEWLPEPATRALAG 1737

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
            +A  HGLT++T VL AWA+VL+RL  R DVVFG+VVSGRP  +P VE MVG+FIN VP  
Sbjct: 1738 FARGHGLTVSTIVLGAWALVLARLAGRTDVVFGSVVSGRPADVPDVERMVGMFINTVPAR 1797

Query: 296  HYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIR 355
              + G   ++     +Q + +A+ +  YL L EIQ+  G G +FD++ + EN P D A  
Sbjct: 1798 VRLDGRRPLLEMLEDLQARQAALTEHQYLGLPEIQKVAGTGAIFDTIVMVENYPHDAA-- 1855

Query: 356  PATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTV 415
                  G     V   + T YPLT+   L                    AAE+  +++ V
Sbjct: 1856 GLGGDGGVAISSVVTRTGTSYPLTMNVSLGDRLRITVSYRPDRIDD-ATAAEVARQVVRV 1914

Query: 416  LRQL---PDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXX 472
            L ++   P +  G        T A +         +A   +T+V E+F RQ         
Sbjct: 1915 LERVVAEPSLPVGRLGVTSEPTRAAVVERWNSTGEAAA--ETSVLELFRRQA--GASPDA 1970

Query: 473  XXXXXGVRH-TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXX 531
                 G R  +YA+L   + RLAG LA  GVG    V +V+ R                 
Sbjct: 1971 VAVVAGERTLSYADLDRESDRLAGHLAGIGVGRGDRVGVVMTRGADLFVALLGVWKAGAA 2030

Query: 532  YLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAA 591
             +PV+V  P+ R+E ++     ++A+      + V   V  + +D P     I      A
Sbjct: 2031 QVPVNVDYPAERIERMLADVGASVAVCVEATRKAVPDGVEPVVVDLPV----IGGVRPEA 2086

Query: 592  PTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXH 651
            P V       AYV++TSGSTG PK V   + +V +  +D                    H
Sbjct: 2087 PPVTVGAHDVAYVMYTSGSTGVPKAVAVPHGSVAALASDPG----WSQGPGDCVLLHASH 2142

Query: 652  AWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSA 711
            A+  S    W P+V    G  + + +   + DA+RL E ++ G +  +  T   F  ++ 
Sbjct: 2143 AFDASLVEIWVPLV---SGARVLVAEPGTV-DAERLREAVSRG-VTTVHLTAGAFRAVAE 2197

Query: 712  AGLLDH-NLSVLALGGEAINTGLWDQLR-GLSQMAVYNCYGPTEMTVEXXXXXXKDYRKP 769
                    L  +  GG+A+      ++R     + V   YGPTE+T+       +     
Sbjct: 2198 ESPDSFIGLREILTGGDAVPLASVVRMRQACPDVRVRQLYGPTEITLCATWLVLEPGAAT 2257

Query: 770  ----TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL 825
                 IG   AG   YV D+ L+ V   V GELYL+GA LA GY+G    T+ RFVA+P 
Sbjct: 2258 GDVLPIGRPLAGRQAYVLDAFLQPVAPNVTGELYLAGAGLAHGYLGNTAATSERFVANPF 2317

Query: 826  RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSV 885
              G RMYRTGDL R    G   + GRAD+QVKIRGYRVE GE+E AL   P V  A V  
Sbjct: 2318 SGGGRMYRTGDLARWTDQGELVFAGRADSQVKIRGYRVEPGEVEVALTEVPHVAQAVVVA 2377

Query: 886  LR-QQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDG 944
               Q     L+ +V  +     +   +RA L  RLP +MVP+ +V L   P+  NGK   
Sbjct: 2378 REGQPGEKRLIAYVTAEAGSALESAAVRAHLATRLPEFMVPSVVVVLESFPLTLNGK--- 2434

Query: 945  HALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAV-PHIDDDLFLFGMDSIVAI 1003
              +DR A  A             T+ ERVLC LF E L       DD  F  G DSI+++
Sbjct: 2435 --IDRAALPAPEFAGKAAGREPRTEAERVLCGLFAEILGLERVGADDGFFELGGDSILSM 2492

Query: 1004 SLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYE 1063
             L  +ARR+      + V    T   + A  +    S+ A      G V   P+V  L E
Sbjct: 2493 RLAARARRENFVFGAKQVFEQKTPAGIAAVAERGGQSRPAGVADGVGEVPWTPVVRALLE 2552

Query: 1064 YG----NYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEG--PRLVTR 1117
                          V +  P  +  +++   L  ++D HD LRS + E+ EG  PRLV  
Sbjct: 2553 RDPAGLTRGAMAQWVSVAAPRDLSVTALVAGLGAVIDTHDMLRSRIVES-EGVEPRLVVA 2611

Query: 1118 EPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRAD 1177
                V A  ++ R+   E  D +LA      A     ++DP AG +VRA+W      R  
Sbjct: 2612 GRGTVDAAALVERV---EAGDGDLAEIADRCAHDTAARLDPVAGVLVRAVWVDAGPGR-- 2666

Query: 1178 PANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRAS 1237
             A  L++ AHHL VDVVSW  +L DL AA  ++ AG  P + P   S+RRW   +   A+
Sbjct: 2667 -AGRLVVAAHHLVVDVVSWRTLLPDLQAACEAVVAGGQPALDPPDVSFRRWSRTLDGEAA 2725

Query: 1238 APQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVD----VTERVLGAV 1293
                  +   W  ++      LG    DP RDT ST       +P +    + E+V  A 
Sbjct: 2726 IR--TGELAVWTEILDGAQSRLG--ELDPRRDTVSTAGRRSWTVPREHAGVLVEQVTSAF 2781

Query: 1294 RRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTN 1353
                GV E+LLA  A AVA WR          V+V +EGHGR   + + D + T+GWFT+
Sbjct: 2782 H--CGVHEVLLATLAGAVAGWR------GGTAVVVDVEGHGR-QPLGELDLSRTLGWFTD 2832

Query: 1354 AFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVD 1413
              P+RL      VD  +A     AA  L+  V  ++ A+P+ GL YG+LRY++     V 
Sbjct: 2833 VHPLRL--DVTGVDPAEAVAGGDAAGRLLKQVKENVRAVPDGGLGYGMLRYLNAETGPVL 2890

Query: 1414 AVDP--QIQFSYLGRLDLG-GVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGV 1470
            A  P  +I F+YLGR   G G   QPW  +TG    A     E D PLR  + +   V  
Sbjct: 2891 AALPKAEIGFNYLGRFSAGSGGEAQPWQ-ITGIVGGA----AEQDTPLRHVVEIDAVVVD 2945

Query: 1471 TAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
              +G +      W+  +   ++ + L   W   +A LAA
Sbjct: 2946 GPDGPEFTLTVTWAGRMLGDAEAESLAQAWLDMLAGLAA 2984



 Score =  437 bits (1123), Expect = e-120
 Identities = 349/1074 (32%), Positives = 498/1074 (46%), Gaps = 67/1074 (6%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AA P + D+  LSPLQEGL   H   + G D+Y+    + IDGP+D+   R S   +LDR
Sbjct: 3014 AAVPGLLDIWPLSPLQEGLL-FHAADDRGPDVYASMRTLAIDGPLDVARFRASWTVLLDR 3072

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATP-------AEFDSIARSERRRPFDLS 115
            HP LRA+F   +  + VQ++       W E   +        AEFD +A       FDL+
Sbjct: 3073 HPALRASFHQLESGEAVQVIARDVPPDWRETDLSGLPESEALAEFDRLAARMHAERFDLT 3132

Query: 116  RGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXX 175
            + P LR+ ++ + G+ + R+IFT+HHI+ DGWSL +   ++L                  
Sbjct: 3133 KAPQLRLHLVRL-GDRRYRLIFTSHHIVADGWSLPLILVDVLTAYEAGGDGRTLPAATSY 3191

Query: 176  XXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATA-GQSKPGKTELLLPAADTARLR 234
              ++ W+ +QD+ AA   W   L G+ E   V    +     +P +    L    + RL 
Sbjct: 3192 RDFLAWVDRQDKGAAGQAWRTELAGLDEATHVVPPGSIITPLEPERVAFELDDETSKRLV 3251

Query: 235  QWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPV 294
            ++  RHG+T NT     WA+ L+RL  R DVVFG  V+GRP ++PGVE+ VGLF+N +PV
Sbjct: 3252 EFTRRHGVTANTLFQGVWALHLARLAGRNDVVFGAAVAGRPPEIPGVESAVGLFMNMLPV 3311

Query: 295  VHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAI 354
               ++G E VV     +Q +  AM    ++ L EI++  G G  FD++ VFEN P   A 
Sbjct: 3312 RARLTGAEPVVDMLKDLQERQVAMMAHQHIGLPEIKQLTGPGAAFDTIVVFENYP--PAP 3369

Query: 355  RPATTPDGAQFLPVEMESLT-HYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERML 413
              +  PD     PV + + T HYPL++ + +                    A E+   +L
Sbjct: 3370 PRSDDPDALVIRPVGIPNDTGHYPLSMRASVAAGPVRGEFIYRPDVVDRTEAGEMVAAIL 3429

Query: 414  TVLRQLP--------DIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQ 465
              L Q+          +G   P+   +      +    LAA + P        +F RQ +
Sbjct: 3430 RALEQVVAEPWTPVGQVGLIGPEQRRLVVDEWNRTDVPLAAETLPV-------LFRRQAE 3482

Query: 466  XXXXXXXXXXXXGVRH-TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXX 524
                        G R  T+  L      LA  L   GV  E  V +++ RS         
Sbjct: 3483 RSPDAVAVED--GARSLTFGGLLGEVEALARLLVGAGVRREHRVGVLVERSAELAVTMMA 3540

Query: 525  XXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESI 584
                   ++PVD   P  RVE ++  ++P + +     ++    AVP    +    V  +
Sbjct: 3541 VSFAGGVFVPVDPDYPRERVEFMLANSAPGVMVC----TKTTRAAVPA---EFAGTVLVL 3593

Query: 585  SRRSAAAPTVDR---RPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXX 641
                AA P V+     PE +AYVI+TSGSTG PKGV+ T++ + +    H ER+      
Sbjct: 3594 DELPAADPDVELPPVAPEDAAYVIYTSGSTGVPKGVLVTHSGLANLGYAHIERMAVTSSS 3653

Query: 642  XXXXXXXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMID 700
                        +  FDA    + + LL G  + L DA  M     L E I    I  + 
Sbjct: 3654 RVLQLS------ATGFDAIVSELYMALLAGATLVLPDAASMPPRVTLGEAIRRAGITHLT 3707

Query: 701  TTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV--EX 758
             +PS+   L++   L   L  +  GGEA+   L D  R      V   YGPTE T+    
Sbjct: 3708 VSPSV---LASEDDLPDTLRTVLTGGEALPPALVD--RWSPGRRVIQAYGPTETTICSTM 3762

Query: 759  XXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAA 818
                   + +  +G        YV D+ L+ VP GVVGELY++G  LARGY+GRPG+TA 
Sbjct: 3763 SAPLSPGHDQVPLGGPIHNVRHYVLDAFLQPVPPGVVGELYITGVGLARGYLGRPGLTAE 3822

Query: 819  RFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGV 878
            RFVA P  PG+RMYR+GDL R    G   + GR D QVK+RGYRVE  EIEA L   P V
Sbjct: 3823 RFVASPFAPGERMYRSGDLFRWTREGQLLFAGRVDAQVKVRGYRVEPAEIEAVLAEHPWV 3882

Query: 879  HDAAVSVLRQ-QDRTSLVGFVVWQDNMHEDLIKLRAGL----TERLPSYMVPARIVTLPR 933
               AVSV R       LV +VV   +   +   L + L     ERLP YM+PA  V+L +
Sbjct: 3883 GQVAVSVRRDGPGDKQLVAYVVPSADAAAENGTLASALRELAAERLPEYMMPAAFVSLEQ 3942

Query: 934  LPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDL 992
            +P+  NGKLD  AL       ++S       +  T  E  LC LF + L       DD  
Sbjct: 3943 MPLTPNGKLDHRALQAPDFAGMSSKR-----APRTPMEARLCALFADVLGLDQVGPDDSF 3997

Query: 993  FLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAI-DAAVDSQDAPA 1045
            F  G DSI ++ L  +AR  GL + P  V    T  +L   + + A +    PA
Sbjct: 3998 FELGGDSITSMQLSARARPTGLELTPWQVFDEKTPERLAVIVQELAAEGGTTPA 4051


>tr|C1BBK7|C1BBK7_RHOOB Tax_Id=632772 SubName: Full=Non-ribosomal
            peptide synthetase;[Rhodococcus opacus]
          Length = 5599

 Score =  640 bits (1652), Expect = 0.0
 Identities = 501/1527 (32%), Positives = 711/1527 (46%), Gaps = 87/1527 (5%)

Query: 10   DVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAA 69
            DVL L+PLQ+G++      + G D Y +Q V+++ GPVD   L R  QA++DRH  LRA 
Sbjct: 1553 DVLPLTPLQDGIYFQSAFDDTGADPYVVQQVIELTGPVDAAALHRGLQAVVDRHAALRAG 1612

Query: 70   FWDRDVPKPVQIVPVHAALPWS----ERVATPAE-FDSIARSERRRPFDLSRGPALRVVV 124
                   + VQ++     +P        VA PA+  + +  ++R R FD  RGP LR  +
Sbjct: 1613 VRAVSDGRVVQVIGDDVRVPMEVLDLTGVADPAQRVEEVLTADRARGFDFGRGPLLRYTL 1672

Query: 125  LSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAK 184
              + G TK  ++ + HH++ DGWS+ V   EL+A+                  Y+ WL  
Sbjct: 1673 ARLDG-TKFLLLQSIHHLVADGWSVPVMLRELMALYSVEGKPLALPTPTPYRNYLEWLGA 1731

Query: 185  QDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRHGLTL 244
            +DR A+LA W + L    EP+ +      G+       + LP+  TA L       GLTL
Sbjct: 1732 RDRQASLAVWREALADAPEPVELPAPTPKGEFGIRSVRVALPSEATAALTAVGRARGLTL 1791

Query: 245  NTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEAV 304
            +T V   W +VL RLT R DV+FG+ VSGR   LPG+ETMVGLFIN VP       T+ V
Sbjct: 1792 STLVHGTWGLVLGRLTGREDVLFGSTVSGRGGDLPGIETMVGLFINTVPARLRYRPTDTV 1851

Query: 305  VAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDGA- 363
                 + Q + S + D  YL L+E++RE G   LF++L VFEN P+ D       P GA 
Sbjct: 1852 AGALARWQHEQSTLLDHQYLGLAELRREAGLQNLFETLVVFENYPLGDG--AVADPSGAI 1909

Query: 364  QFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQLPDIG 423
            Q   +  +    Y +T++  +                    AA   E  +  L +L    
Sbjct: 1910 QLTGIRFDEHPPYAMTLIV-VPGDALTLELKYDAARVDRATAARFAESTIAYLAELTRDV 1968

Query: 424  DGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTY 483
            D T   + + +   ++A   L        DTTV  + E Q +                TY
Sbjct: 1969 DQTVSAVALASREPIEA--ALRDVEVEFPDTTVTALLEEQAERTPDAVAVVFEDD-HLTY 2025

Query: 484  AELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSAR 543
            AELHARA RLA  L E GV PE+ VA+ LPRS                Y+P+D   P+ R
Sbjct: 2026 AELHARANRLARLLVERGVAPESKVAVALPRSLDLMVALLAVGKAGGAYVPLDTGYPADR 2085

Query: 544  VESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPT--VDRRPEQS 601
            +  ++  A P   +T+     L G+ VP + + D       + R +  P   +   P+  
Sbjct: 2086 LAYMLADAQPVCVLTDGTV-PLAGSGVPEVRVAD-------ADRYSPEPLTGIALAPQHP 2137

Query: 602  AYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASW 661
            AYVI+TSGSTG PKGVV  +A +++        ++                   SFD S 
Sbjct: 2138 AYVIYTSGSTGRPKGVVVPHAGIVN------RLLWVQRFRPITASDNVFQKTPSSFDVSV 2191

Query: 662  QPMVG-LLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSA--AGLLDHN 718
                G LL G  + L   +  +D   L + I    I  +   PSM     A  A      
Sbjct: 2192 LEFFGPLLAGATLVLARPDGHKDPAYLADVIVRQSITRVHFVPSMLEVFLADPAAARCTG 2251

Query: 719  LSVLALGGEAINTGLWDQLRG-LSQMAVYNCYGPTEMTVEXXXXXXK---DYRKPT--IG 772
            L +++  GEA+      ++   L  + + N YGPTE +V+          +   P+  IG
Sbjct: 2252 LRIISCSGEALPVASARRVAELLPGVELDNLYGPTEASVDVSYAASVQGIEAAAPSVPIG 2311

Query: 773  TANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRM 831
               + T  YV D  L+ VP G  GELYLSG QLARGY+GRPG++A RFVADP  R G RM
Sbjct: 2312 LPTSNTGLYVLDRYLQPVPAGAAGELYLSGPQLARGYLGRPGLSAERFVADPFSRNGSRM 2371

Query: 832  YRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQ-D 890
            YRTGD+ R  + G   Y+GR D QVK+RG+R+E+GEIEA +   PGV  AA  V   +  
Sbjct: 2372 YRTGDVARVNADGAVEYLGRIDDQVKLRGFRIELGEIEARMADCPGVRQAAAVVRSDRPG 2431

Query: 891  RTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRL 950
            +  LVG+VV       D   +RA L   LP +MVP   V L   P+  +GKL+  AL   
Sbjct: 2432 QQQLVGYVVGD----ADPGDVRARLASALPEFMVPVAFVNLAEFPLGPSGKLNRKALP-- 2485

Query: 951  AEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLFGMDSIVAISLVHKA 1009
            A D     +   AV +   T  +L   + E L      +DDD F  G DSI+AI LV+ A
Sbjct: 2486 APDFAAQATAEPAVESG--TAGMLAAHYAEVLGLGEVGVDDDFFALGGDSILAIRLVNLA 2543

Query: 1010 RRQGLRVDPRMVLTATTIRQLGAAI-DAAVDSQDAPADADYGAVRPLPMVSWLYEY-GNY 1067
            RR+G+ V PR +    T   L   + D AV       D+  G + PLP+V  L E+ G  
Sbjct: 2544 RREGITVTPRQIFEQRTPAALARLVADPAVAQPPRVEDSGIGVLLPLPVVHRLSEWSGGK 2603

Query: 1068 RRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDV 1127
             RF   VLL  P+G D + +   L  ++  HD LR  LT    G   V     A  A+  
Sbjct: 2604 NRFNQAVLLHTPAGTDATVLTAALHAVIGHHDGLRQKLTRHAPG---VWSLEIAATADLT 2660

Query: 1128 LTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANI--LLLT 1185
            L R+ +     D L   VA  +    D+++P  G M+ A+WF      A P  +  LLL 
Sbjct: 2661 LRRVDVTGLDADALRETVAAESDAAADRLNPDDGIMLSAVWF-----DAGPRELGRLLLV 2715

Query: 1186 AHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQR 1245
            AHHL +D VSW  ++ DLA AW +  +G    + P  TS R +  ++  +A  P    + 
Sbjct: 2716 AHHLVIDGVSWRTLIEDLAMAWVAADSGENAALDPVPTSLRGFTRVVTEQAQEPARLAEL 2775

Query: 1246 DYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQG--VRELL 1303
            D+W   +R   P   L          S        +   +T  +L  V    G  V ++L
Sbjct: 2776 DHW---LRVTGPGADLVPGTEGHAVVSGGARRTVCLDRQLTTALLTTVPAVVGADVTDVL 2832

Query: 1304 LAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGA 1363
            LAA  ++   W   R +  A  +LV LE HGR +     D + TVGW TN  PVRL + A
Sbjct: 2833 LAALRLSADRWLAERGR--ANDLLVDLERHGREELAAGVDLSRTVGWLTNVTPVRLRSRA 2890

Query: 1364 AAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDG--VAELVDAVDPQIQF 1421
             A+             D +  V   L   P+ G+ YG+LRYV+      L    + Q+ F
Sbjct: 2891 GAL-------------DTLKDVKEQLRGAPDGGIGYGMLRYVNARTAGLLAARSESQVLF 2937

Query: 1422 SYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNW 1481
            +YLGR+        PW+       D+L  DP+ DL   + L ++     +A+G +L   +
Sbjct: 2938 NYLGRMP--HTPPGPWTQAVES--DSLATDPDADLGGPYRLVINALCEESAQGAELQAVF 2993

Query: 1482 RWSDAVFERSDIDHLTGLWQRGIAALA 1508
             WS+A    +D   L+  W   +  LA
Sbjct: 2994 AWSEADLSEADTVALSDGWVAALRELA 3020



 Score =  575 bits (1483), Expect = e-161
 Identities = 462/1403 (32%), Positives = 656/1403 (46%), Gaps = 93/1403 (6%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            V A+   ++ VL LSPLQEGL+      + G D+Y+ QF +D +  +D + L  + + + 
Sbjct: 3051 VQASPSGVDTVLPLSPLQEGLY-FQAGFDSGNDIYTAQFSLDFEHRLDTDRLAAALRTLQ 3109

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSE---RVATPAEFDSIARS----ERRRPFD 113
             R+P LRA F    +P PVQ       +P SE   R     E DS A      +R  PFD
Sbjct: 3110 RRNPTLRAGFVSAGLPAPVQFFGTGLDVPVSEFDLRELDETERDSYAAQLTAQDRLTPFD 3169

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            L+  P  R +VL + G++  R++     +L DGWS  +   +LLA+              
Sbjct: 3170 LTSPPLWRAMVLRL-GDSHDRLVINRQFLLWDGWSNGIVVGQLLALYESGGDDSGFPAPE 3228

Query: 174  XXXX-YIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTAR 232
                 Y+ WLA +D  AA + W D L G+ EP ++A   T     P + + +LP   + R
Sbjct: 3229 GSFEDYLQWLATRDADAAQSAWTDALGGLDEPTLLAATITGDPEPPQRRDAVLPEDLSER 3288

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            LR  A   G+T N  +  A AVVL   T RRD+VFGT V+GRP ++PG++ + G+F+N V
Sbjct: 3289 LRAGARGAGVTFNAVLNAALAVVLGIETGRRDLVFGTTVAGRPPEVPGIDAVTGMFLNTV 3348

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDD 352
            PV   +   E V     ++Q +  A+    YL L+ IQR      LFD L+V +N  +D+
Sbjct: 3349 PVRTTLRPDETVADLLRRIQSERLALTPYDYLGLASIQRVSEHRQLFDVLYVLQNF-VDE 3407

Query: 353  ----AIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEI 408
                A+  A    G   +       THYP+TVV                     +PA+ +
Sbjct: 3408 KQVSALNAAHDISGGDSI-----DHTHYPVTVV----VTPGASVKVKFEFHPEKIPASRV 3458

Query: 409  GERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMF-ERQVQXX 467
             ERML+   +   + +    DL         A   + A      D T+ ++F E  +   
Sbjct: 3459 -ERMLS---RYVTVLEEWSTDLSGPVGGIAGAALPVPAEPKALPDATIADLFAEAALVRP 3514

Query: 468  XXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXX 527
                       V  +YAEL A   R+A  L  HG GPE +VAL LPR+            
Sbjct: 3515 GETALVFGDRAV--SYAELDADVNRMARLLLGHGAGPERIVALALPRTVEMVVALFAVLR 3572

Query: 528  XXXXYLPVDVTLPSARVESIVRQASPALAITEADYS-QLVGTAVPTLALD--DPAAVESI 584
                YLP+++  P+ R+ +++  A PA+ +T +D +  L   AV TLA+D  D  AV S 
Sbjct: 3573 TGSAYLPLELDHPAERLVAMLDDARPAVLVTTSDVAGTLAAAAVDTLAVDTLDLGAVGSA 3632

Query: 585  SRRSAA----APTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXX 640
                A     AP    R +  AYVI+TSGSTG+PKGVV     + +   +H E ++    
Sbjct: 3633 PLSEAELGGFAPGTPGRLDHPAYVIYTSGSTGKPKGVVTPYRGLTNMQFNHREAIFEPVV 3692

Query: 641  XXXXXXXXXX-HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMI 699
                       H  S +FD SW+ ++ L++GHE+H+ D    RDA+ LV      +ID++
Sbjct: 3693 AAAGGRRLRIAHTVSFAFDMSWEELLWLVEGHEVHICDENLRRDAEALVAYCDTHEIDVV 3752

Query: 700  DTTPSMFVQLSAAGLLD-----HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEM 754
            + TP+    L   GLLD     H   ++ LGGEA++  +W++LR       YN YGPTE 
Sbjct: 3753 NVTPTYAQHLIEEGLLDDGPGRHRPPLVLLGGEAVSDSVWNRLRDTDGTCGYNLYGPTEY 3812

Query: 755  TVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPG 814
            T+        D   PT+GT    T  YV D+ LR VPDGV GELY+SG  LARGY+ R  
Sbjct: 3813 TINTLGAGTADSATPTVGTPIWNTSAYVLDAWLRPVPDGVPGELYISGVGLARGYLDRFA 3872

Query: 815  MTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRG 874
            +TA RFVADP R   RMYRTGDLVRR S G   ++GR D QVKIRG+RVE+GEI +AL  
Sbjct: 3873 LTAERFVADPFRESVRMYRTGDLVRRASDGNLDFLGRTDDQVKIRGHRVELGEIASALEA 3932

Query: 875  QPGVHDAAVSV-LRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPR 933
              GV  AAV V         LVG+ V       D+      L   LP YMVPA ++ +  
Sbjct: 3933 LDGVRQAAVVVDSGPGGFKRLVGYAVVSTCQPPDVNNYSRALRATLPDYMVPAAVIEVDG 3992

Query: 934  LPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDL 992
            LP+  NGKLD  AL   + D +   SGG      TDTERVLCELF + L   VP +DDD 
Sbjct: 3993 LPMTVNGKLDVKALP--SADDVLGRSGGVRTEPRTDTERVLCELFGDILGVPVPGVDDDF 4050

Query: 993  FLFGMDSIVAISLVHKARRQGLRVDPRM--VLTATTIRQLGAAIDAAVDSQDAPADADYG 1050
            F  G  S++A  L+ +A R  L  D  M  +  A T+ +L A I     S   P  A   
Sbjct: 4051 FDLGGHSLLATRLISRA-RAALDADLTMRDLFEAPTVAELAARIGEDTAS-TRPVLAAGP 4108

Query: 1051 AVRPLPMVS-----WLYEY--GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRS 1103
                LP+ +     WL +        +   ++LRL   +D    E  L  ++  H++LR+
Sbjct: 4109 RPEHLPLSAAQQRLWLLQQMEDASAAYNFPIVLRLQDALDPEVFEQALTDVVSRHESLRT 4168

Query: 1104 ILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAM 1163
            +  E          EP  V  + V   + + +G++       A   R+VT+ +      +
Sbjct: 4169 VFGEH-------DGEPVQVILDGVRPGVAVVDGTE-------ADVVRLVTETVGRPFD-L 4213

Query: 1164 VRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFT 1223
               I  R +  R     +L +  HH+A D  S    L DL  A+ +   G+ P   P   
Sbjct: 4214 ATEIPVRASLIRLGDQQVLAIVLHHIATDEWSDRPFLRDLMTAYAARAQGSAPGWAPLAV 4273

Query: 1224 SYRRWCELMWHRASAPQVQD-------QRDYWAALVREPDPALGLRYPDPTRDTWSTLQL 1276
             Y  +   +W R      QD       Q DYWA  +      L L   D TR    +   
Sbjct: 4274 QYADY--TLWQRDVLGDPQDPSSLVSRQLDYWARTLDGAPEELVLP-ADRTRPARPSFAG 4330

Query: 1277 TRAAIPVDV-TERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGR 1335
                  +D  T R L ++ R  G    ++   A A    R     D   G  VA    GR
Sbjct: 4331 GAIETTLDAETTRALRSLARTSGTSMFMVLHAAAAALLHRLGAGDDLPIGAPVA----GR 4386

Query: 1336 ADAVLDTDTTNTVGWFTNAFPVR 1358
            ++  LD    + +G+F N   +R
Sbjct: 4387 SEQGLD----DLIGFFVNTVVLR 4405



 Score =  444 bits (1142), Expect = e-122
 Identities = 358/1079 (33%), Positives = 491/1079 (45%), Gaps = 75/1079 (6%)

Query: 455  TVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPR 514
            TV E+F  QV              VR TY +L  R  +L   L + GVGPETVVA+ LPR
Sbjct: 494  TVPELFHAQV-LRTPDAEALIAGDVRLTYRDLGERVAQLTRHLLDRGVGPETVVAIGLPR 552

Query: 515  SERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLA 574
            S                ++P+D + P  R  S++  A  +L +T        G     + 
Sbjct: 553  SAEMVTGLLAVMCSGGAFVPLDPSWPQDRRTSVLADAGASLVLTGPGGVTDAGERAVPVD 612

Query: 575  LDDPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAER 634
            L   A  E    +    PTV  +  + AYVIFTSGSTG PKG +  + AV +      + 
Sbjct: 613  LASWAYAE----QPTEPPTVTVQGARLAYVIFTSGSTGRPKGAMIRHEAVCARLLWQRDE 668

Query: 635  VYXXXXXXXXXXXXXXHAWSLSFDASWQP-MVGLLDGHEIHLFDAEEMRDADRLVEGIAI 693
            +                   LSFD S    ++ L+ G  + + +    RD   L++ IA 
Sbjct: 669  ILGFGPADASLFKAP-----LSFDISVNEILLPLVSGGRLVVAEPGGERDPQYLLDLIAR 723

Query: 694  GQIDMIDTTPSMF-VQLSAAGLLDHNLSVLA---LGGEAINTGLWDQLRGLSQMAVYNCY 749
              +  +    SM  V L  +   DH LS L     GGE +   L+++ R    + +Y+ Y
Sbjct: 724  ESVTFVYLVSSMLDVLLDLSRGTDH-LSALKHVWCGGEVLTPRLFERFRAQLAITMYHGY 782

Query: 750  GPTEMTVEXXXXXXKDYRK---PTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLA 806
            GP E T+       ++       +IG  N  T  YV D  L  VP G  GELY  G  L 
Sbjct: 783  GPAEATIGVSHVIYREDAARIATSIGRPNPDTQLYVLDEHLNPVPLGTGGELYAGGFLLG 842

Query: 807  RGYVGRPGMTAARFVADPLRP-GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEV 865
            RGYV  PG+TA+RFVA+P    G R+YRTGDL R    G   ++GRAD QVKIRG R+E+
Sbjct: 843  RGYVDAPGLTASRFVANPFATDGSRLYRTGDLARWAPDGSLDFLGRADNQVKIRGMRLEL 902

Query: 866  GEIEAALRGQPGVHDAAVSVLRQQDRTS-LVGFVVWQDNMHEDLIKLRAGLTERLPSYMV 924
             ++EA +   P V  +AV V         L  +VV +     D+ +LRA  + +LP YMV
Sbjct: 903  EDVEAGIVSHPAVRHSAVVVRETPSGAKYLAAYVVAKQGSVPDVAELRAWASSKLPEYMV 962

Query: 925  PARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA 984
            P+  V L R P+  NGKLD  AL      A      G  V+  T  E  LC L    L  
Sbjct: 963  PSAFVILDRFPLTPNGKLDRRALPEPDLGA-----AGENVAPRTAAEETLCALMAGVLGV 1017

Query: 985  VP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAID----AAVD 1039
                + DD F  G DSIVAI LV+ ARR+GL + PR V    T   L  A D    AAVD
Sbjct: 1018 ESVGVTDDFFALGGDSIVAIQLVNHARREGLSISPREVFQLRTAEALARAQDGRTAAAVD 1077

Query: 1040 SQDAPADADYGAVRPLPMVS-WLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGH 1098
            S D       G VR  P+++      G    F  +VL++ P+ +D S+    L  +L+ H
Sbjct: 1078 SDDIAV----GDVRCTPILARTAARGGEIAAFHQSVLVQTPAALDESAARTALAAVLERH 1133

Query: 1099 DTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDP 1158
            D LR+ L    +   L   EPA    + +L R+   +GS ++L S    A      ++DP
Sbjct: 1134 DALRATLVRGEQW-MLSVPEPAPASMDGIL-RVVEFDGSAEQLDSETQAAVA----RLDP 1187

Query: 1159 SAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKI 1218
             AG M++A+ F   E    P  +LL+  HHL VD VSW I+L DLA A  ++ AG  P++
Sbjct: 1188 DAGTMLQAVLFSAAE---GPGRLLLI-GHHLVVDGVSWRIILEDLARAGTAVTAGGVPEL 1243

Query: 1219 LPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTR 1278
             P  TS RRW EL+     +     +  +W+     PDP LG R  DP  D     +   
Sbjct: 1244 PPVGTSLRRWSELLDEHTKSGAFDHELSFWSDAAATPDPLLGSRALDPALDLAGDAETLT 1303

Query: 1279 AAIPVDVTERVLGAVRR--DQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRA 1336
              +P + T  +L  V       V++ LL   A+A+  WR          VL+ +EGHGR 
Sbjct: 1304 VTLPPEFTGPLLSTVPAAFHGHVKDALLTGAAVALRRWR----NGEPGPVLLDVEGHGRE 1359

Query: 1337 DAVL------DTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLE 1390
            + ++        D + TVGWFT  +PV L  GAAA        D     D +  V   L 
Sbjct: 1360 EDLVRRTDGPAIDLSRTVGWFTTVYPVVLDPGAAA--------DEAGIADALKMVKDQLR 1411

Query: 1391 AIPNDGLDYGLLRYVDGV-AELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALP 1449
             +P  G  YG LRY+     E      PQ+ F+YLGR+  G  AD     + G       
Sbjct: 1412 RVPGAGFGYGALRYLGAAEPEFGQEPTPQVLFNYLGRVTSGTGADWLPRAMGGA------ 1465

Query: 1450 IDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
               +P +PL  AL   V     A+G  L     W+  V  R  +  L   W   +  LA
Sbjct: 1466 --DDPRMPLGHALAFDVIAEDGADGPVLRTTLTWAPGVLTRDAVRVLADEWTAVLRVLA 1522



 Score =  344 bits (883), Expect = 5e-92
 Identities = 417/1535 (27%), Positives = 621/1535 (40%), Gaps = 157/1535 (10%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            V AA P+ E  L LS  Q+ L+ L Q+ ED    Y+   V+ +   +D E+  ++   ++
Sbjct: 4103 VLAAGPRPEH-LPLSAAQQRLWLLQQM-EDASAAYNFPIVLRLQDALDPEVFEQALTDVV 4160

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERV-ATPAEFDSIARSERRRPFDLSRGPA 119
             RH +LR  F + D  +PVQ++ +    P    V  T A+   +      RPFDL+    
Sbjct: 4161 SRHESLRTVFGEHD-GEPVQVI-LDGVRPGVAVVDGTEADVVRLVTETVGRPFDLATEIP 4218

Query: 120  LRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELL---AVXXXXXXXXXXXXXXXXX 176
            +R  ++ +  +    ++   HHI  D WS   F  +L+   A                  
Sbjct: 4219 VRASLIRLGDQQVLAIVL--HHIATDEWSDRPFLRDLMTAYAARAQGSAPGWAPLAVQYA 4276

Query: 177  XYIVWLAK-----QDRSAALAGWMDY----LRGVSEPLMVAYEATAGQSKP----GKTEL 223
             Y +W        QD S+ ++  +DY    L G  E L++  + T   ++P    G  E 
Sbjct: 4277 DYTLWQRDVLGDPQDPSSLVSRQLDYWARTLDGAPEELVLPADRTR-PARPSFAGGAIET 4335

Query: 224  LLPAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVET 283
             L A  T  LR  A   G ++   +  A A +L RL    D+  G  V+GR +Q  G++ 
Sbjct: 4336 TLDAETTRALRSLARTSGTSMFMVLHAAAAALLHRLGAGDDLPIGAPVAGRSEQ--GLDD 4393

Query: 284  MVGLFINAVPVVHYVSGT---EAVVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGP 337
            ++G F+N V +   VSG    + ++A+       + A  DV + ++ E     R   R P
Sbjct: 4394 LIGFFVNTVVLRTDVSGNPTFDQLLARVRDTDLAAFAHSDVPFETVVEKVNPARTLARNP 4453

Query: 338  LFDSLFVFENAPIDDAIRPATTPDGAQFLPVEMESLT---HYPLTVVSHLRXXXXXXXXX 394
            LF  +  + +   D A        G+   PV  E  T           +L          
Sbjct: 4454 LFQVMAGYHSRTSDSA-----QAAGSALTPVVFEERTAKFDLVFNFTEYLDDDRVELRLE 4508

Query: 395  XXXXXXPYLPAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAE--LKAHGLLAARSAPTF 452
                      A +I  R + VL  +         DLD+    E  L  HG     + P  
Sbjct: 4509 YGSDLFDKDTAEKIARRQVAVLGAVASDSGLAVGDLDVFLGGERELVVHGFNDT-AQPVA 4567

Query: 453  DTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVL 512
            + T +E F R V             G   TYAEL ARA R+AG L   GV  E VV L +
Sbjct: 4568 EETFYEAFARHVAATPDAVAVVDAAGAV-TYAELSARADRIAGLLHRRGVSAEGVVGLAV 4626

Query: 513  PRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTA--V 570
            PRS +              YLP+D+  PS R+  ++  ++  + +T A  S  +     +
Sbjct: 4627 PRSSQMVAVVLGVLKLGAAYLPLDLNHPSDRISYMLADSAARVLVTTAGESPRIAEVDGL 4686

Query: 571  PTLALDDPA-AVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFA 629
              + LDD A A E  +      P   +  + +AYVI+TSGSTG+PKG + T+  + S  A
Sbjct: 4687 VRVLLDDAAVAAELDTEHGTQVPPAPQGLDHAAYVIYTSGSTGKPKGTILTHDGIPSLVA 4746

Query: 630  DHAERVYXXXXXXXXXXXXXXHAWSLSFD-ASWQPMVGLLDGHEIHLFDAEEMRDADRLV 688
               +R+                  S+ FD A ++  + L  G  + +   E       L 
Sbjct: 4747 TAEQRMKLVPGSVVMQFA------SIGFDVAVFELSMALCTGSRLVIVPDESRVAGSELT 4800

Query: 689  EGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNC 748
            + +A   +      PS+   L A   +    +VL +G E +   L    R   ++ +   
Sbjct: 4801 DFMAAHSVTHAIIPPSLLAALPAGCDVPEGCTVL-VGTETVPPELIG--RWAERLNLLAA 4857

Query: 749  YGPTEMTVEXXXXXXKDYRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLA 806
            YG TE TV       +        IG  +     YV D  L+ VP GV GELY++G  LA
Sbjct: 4858 YGLTEATVNNTLWQAQPGWNSAVPIGIPDPNEQAYVLDDLLQPVPPGVAGELYIAGRGLA 4917

Query: 807  RGYVGRPGMTAARFVADPLR-PGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEV 865
            RGY+GRP +T+ RFV  P    G RMYRTGD  R  + G   ++GR D QVKIRG+R+E+
Sbjct: 4918 RGYLGRPDLTSVRFVPSPFGGAGTRMYRTGDRARWRADGNIDFLGRVDDQVKIRGFRIEL 4977

Query: 866  GEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLI---KLRAGLTERLPSY 922
            GEI AAL     V  +AV   R  D   LVG+V   D    + I    +R     RLP Y
Sbjct: 4978 GEIIAALGSHSAVKQSAVVADRSGDIVRLVGYVTPADGHGAEQIDPQAVREHAAARLPDY 5037

Query: 923  MVPARIVTLP-RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQ 981
            MVP  +V L   LP+  NGKLD  AL      ALT    GT     T  ++ +   F E 
Sbjct: 5038 MVPTLVVVLDGDLPLTPNGKLDRRALPLPDWSALT--GDGT---PQTPEQKEIAAAFAEI 5092

Query: 982  LNAVP-HIDDDLFLFGMDSIVAISLVHKAR-RQGLRVDPRMVLTATTIRQLGAAIDAAVD 1039
            L+     I D+ F  G +S+ ++ LV + R R  + +  R V  ++T+ +L A + AA  
Sbjct: 5093 LHLPSVGIHDNFFDLGGNSMASMRLVGRIRGRFAVDIGIRDVFDSSTVAELSAIVAAATS 5152

Query: 1040 SQDAPADADYGAVRPLPMVS-----W--LYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQ 1092
            +              LP+       W      G   R +H + L+L   +D   +   L 
Sbjct: 5153 TGRPVLTVADPRPETLPVSGPQRRFWKQFRAAGADARASHALSLQLRDTVDPEILAQALD 5212

Query: 1093 LLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDV------LTRITLPEGSDDELASAVA 1146
             +   H+ LR++  E   G  +  +E    R E V      + R    +           
Sbjct: 5213 DVTSRHEPLRTVYVEV--GDTVFAQEAVRPRLELVDVGDGDVHRTVFEDVHRTVFEDVHR 5270

Query: 1147 HAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAA 1206
                +    +D +  A +R     G    AD    LLL  H++AVD  S   +LGDL  A
Sbjct: 5271 TVFELAQQPLDLTGHAPLRVHLVTG----ADGTQALLLAMHYIAVDEWSVVPLLGDLMGA 5326

Query: 1207 WRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQR-----DYWAALV-----REPD 1256
            + +   G  P+  P    Y  +       A AP   D R      YW   +     R   
Sbjct: 5327 YAARSQGEEPEWEPLPVGYADYVVWSQALAGAPGDPDSRRSRQLAYWRETLDGMPSRLEL 5386

Query: 1257 PALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRR---DQGVRELLLAATAMAVAS 1313
            PA  +R P            T   +PV++   +  A ++   D G    ++   A+A   
Sbjct: 5387 PAPAVRGP-----------RTAEIVPVEIDAELHSAAQKFAGDTGTSLFMVLQAALATVL 5435

Query: 1314 WRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAER 1373
             R     D   G LVA    GR +  LD      VG F N   +R             + 
Sbjct: 5436 TRHGAGTDIPLGSLVA----GRTEEALDA----LVGCFFNIVLLRTDT--------SGDP 5479

Query: 1374 DPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVD--AVDPQIQFSY-----LGR 1426
            DPV        ++  + A   D LD   + + D    L D   + PQ+   +     LG 
Sbjct: 5480 DPV-------QLLQRIRAANLDALDNQDVAFADVAEALGDTPVLRPQVMIVHHEQARLGH 5532

Query: 1427 LD-LGGVADQPWSLLTGPYLDALPIDPEPDLPLRF 1460
            LD LGG    P  +            P+ DL L F
Sbjct: 5533 LDALGGFMPVPVGV------------PDSDLTLSF 5555



 Score = 39.3 bits (90), Expect = 4.4
 Identities = 39/160 (24%), Positives = 63/160 (39%), Gaps = 8/160 (5%)

Query: 2    TAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLD 61
            TAAA   +D+         + A        +  +    +V     +D    R +  A+L+
Sbjct: 1072 TAAAVDSDDIAVGDVRCTPILARTAARGGEIAAFHQSVLVQTPAALDESAARTALAAVLE 1131

Query: 62   RHPNLRAAF-----WDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSR 116
            RH  LRA       W   VP+P     +   L   E   +  + DS  ++   R  D   
Sbjct: 1132 RHDALRATLVRGEQWMLSVPEPAP-ASMDGILRVVEFDGSAEQLDSETQAAVAR-LDPDA 1189

Query: 117  GPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTEL 156
            G  L+ V+ S   E   R++   HH++VDG S  +   +L
Sbjct: 1190 GTMLQAVLFSA-AEGPGRLLLIGHHLVVDGVSWRIILEDL 1228


>tr|B7T1C1|B7T1C1_9BACT Tax_Id=164851 (veg8)SubName:
            Full=Veg8;[uncultured soil bacterium]
          Length = 3992

 Score =  640 bits (1650), Expect = 0.0
 Identities = 500/1500 (33%), Positives = 719/1500 (47%), Gaps = 128/1500 (8%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            +ALSPLQ GL        DG D Y   +++D+ GPVD   LR + +A+L RH  LRA F 
Sbjct: 1    MALSPLQAGLLFHTVYDGDGHDFYIGHWILDLAGPVDAARLRTAWEALLTRHAPLRACFR 60

Query: 72   DRDVPKPVQIVPVHAALPWSERVATPAEFDS-------IARSERRRPFDLSRGPALRVVV 124
             R   + VQI+     LPW  RV   +  D        +A  +R  PFDL+  P LR+ +
Sbjct: 61   QRKSGETVQIIARQPELPW--RVVDLSHLDDAAEAVRELAEQDRTTPFDLANAPLLRLTL 118

Query: 125  LSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAK 184
            + +  ++  R++ T HH ++DGWSL +   EL  +                  Y+ WL++
Sbjct: 119  IRLADDS-HRLVVTCHHTIMDGWSLPIVLDELSTLYQGNSDLPEVTSYRE---YLAWLSR 174

Query: 185  QDRSAALAGWMDYLRGVSEPLMVAYEATAGQSK--PGKTELLLPAADTARLRQWAGRHGL 242
            QD+  AL+ W   LRG  EP +VA  A  G++   P   E+ LP   T  L + A  HGL
Sbjct: 175  QDKEKALSAWAAELRGAEEPTLVA-PADPGRAPGMPESVEVELPENLTRSLDELARSHGL 233

Query: 243  TLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTE 302
            TLNT V  AW++VL++L  R DVVFG VVS RP  LPGVE MVGLF+N VPV   ++G+ 
Sbjct: 234  TLNTVVQGAWSMVLAQLAGRTDVVFGAVVSARPPDLPGVEGMVGLFLNTVPVRVRLTGST 293

Query: 303  AVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDG 362
             V+     +Q++ S +    ++ L++IQ+  G G +FDSL VFE        R    P  
Sbjct: 294  PVIELLKDLQKRRSMLIPDQFVGLADIQQTAGPGAVFDSLLVFE--------RFHEAPAE 345

Query: 363  AQFLPVEMES---LTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQL 419
            A+ L + +       HYPLT+V+  R                   A  I ER+ +VL QL
Sbjct: 346  AKPLGIRVNQGRVAAHYPLTLVAVPRESMLIKLDYLTDLFDE-ATALSIVERLTSVLGQL 404

Query: 420  PDIGDGTPDDLDIRTAAE---LKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXX 476
                  T  D+D+ +AAE   +      AA +AP+      E+F+ QV+           
Sbjct: 405  THAS--TVADVDVTSAAERALVVDEWGAAAEAAPS--RLALELFDGQVESRRDAIAVVDR 460

Query: 477  XGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVD 536
                 +Y  L   A RLAG L   GV     VA+V+ RS                Y+PVD
Sbjct: 461  DQAM-SYGVLAEDAERLAGYLNGRGVRRGDRVAVVVERSHDLIATLLAVWKAGAAYVPVD 519

Query: 537  VTLPSARVESIVRQASPALAITEADY-SQLVGTAVPTLALDDPAAVESISRRSAAAPTVD 595
               P  RV+ ++  A PA  +  A Y   ++   +  + LDDP   +++S  S  +  V 
Sbjct: 520  PAYPLERVKFMLADADPAAVVCTAGYRDSVLDGGLDPIVLDDPQTRQAVSECSRLS--VG 577

Query: 596  RRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSL 655
               +  AYV++TSGSTG PKGV  ++  V +   +   RV               HA+ +
Sbjct: 578  TTADDVAYVMYTSGSTGTPKGVAVSHGNVAALVGEPGWRV----GPDDAVLMHASHAFDI 633

Query: 656  SFDASWQPMV----------GLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSM 705
            S    W P+V          G +DG  +  + A+ +  A        +    + + +P  
Sbjct: 634  SLFEMWVPLVSGARVVLAGSGAVDGAALAAYVADGVTAAHLTAGAFRV----LAEESPE- 688

Query: 706  FVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLS-QMAVYNCYGPTEMTVEXXXXXXK 764
                S AGL +     +  GG+A+     +++R     + V + YGPTE T+       +
Sbjct: 689  ----SVAGLRE-----VLTGGDAVPLAAVERVRRTCPDVRVRHLYGPTEATLCATWLLLE 739

Query: 765  --DYRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARF 820
              D   P   IG   AG   YV D  LR VP GV GELY++GA +A+GY+ RP +TA RF
Sbjct: 740  PGDETGPVLPIGRPLAGRRVYVLDGFLRPVPPGVAGELYVAGAGVAQGYLERPALTAERF 799

Query: 821  VADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHD 880
            VADP     RMYRTGDL      G  A+ GRAD QVKIRGYRVE GEIE  L G PGV  
Sbjct: 800  VADPFVAHGRMYRTGDLAYWTGKGALAFAGRADDQVKIRGYRVEPGEIEVVLAGLPGVGQ 859

Query: 881  AAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANG 940
            A V    +     L+G+ V +     D ++LR  L + LP +MVPA ++ L  LP+  NG
Sbjct: 860  AVVLARDEH----LIGYAVAEAGHELDPVRLREQLADTLPEFMVPAAVLVLGELPLTVNG 915

Query: 941  KLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDS 999
            K+D  AL     D  +  +G    + +TD ERVLC +F E L      ++D  F  G DS
Sbjct: 916  KVDRQALP--GPDFASKAAGR---APATDAERVLCGVFAEVLGLDRVSVEDSFFELGGDS 970

Query: 1000 IVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVS 1059
            I ++ +  +ARR+G+ + PR V    T  +L A    A  ++ A   +  G +   P++ 
Sbjct: 971  ISSMQVAARARREGISLTPRQVFEYRTPERLAALAQEAQPTRRAEV-SGVGEIPLTPVMR 1029

Query: 1060 WLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREP 1119
             L +      F    ++  P+G+++ S+   LQ +LD HD LR+         RL+  EP
Sbjct: 1030 ALGDDAVRPNFAQARVVGTPAGLNQDSLVKALQAVLDVHDLLRA---RVQSDGRLIVAEP 1086

Query: 1120 AAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPA 1179
             AV A  ++TR+    G+ DE+A     AA      ++PSAG M R +W    +  +D  
Sbjct: 1087 GAVNAAGLVTRVAAESGNLDEIAEGQVSAA---MGTLNPSAGIMARVVWI---DAGSDEP 1140

Query: 1180 NILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAP 1239
              L   AHHLAVD VSW I+L DL +A+ ++ AG  P + P  TSYR+W   +  +A + 
Sbjct: 1141 GRLAFVAHHLAVDAVSWGILLPDLRSAYDAVIAGETPALEPAVTSYRQWALRLAEQARSD 1200

Query: 1240 QVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGV 1299
                + D W  L+   +  L       T  + S        +   +  ++  A     G+
Sbjct: 1201 STVAEVDQWVELLDGAESVL----EQQTGQSHSWSDALSGPVARTLVSQLPAAFH--CGI 1254

Query: 1300 RELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRL 1359
            +++LLA  A AVA     R +   AG+LV +EGHGR DA    D   TVGWFT+  PVRL
Sbjct: 1255 QDVLLAGLAGAVA-----RVRGAGAGLLVDVEGHGR-DAADGEDLLRTVGWFTSVHPVRL 1308

Query: 1360 GAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDP 1417
                              A   + +V   + A+P DGL YGLLRY+  +  A L      
Sbjct: 1309 D----------------LADLSLKAVKEQVRAVPGDGLGYGLLRYLNPETAARLAGLPSA 1352

Query: 1418 QIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQL 1477
            QI F+YLGR  L  + +  W +         P+   PD  L   + +   V  T +G +L
Sbjct: 1353 QIGFNYLGRTSL-TLKNPAWEV-----SGEGPLGGGPDTALAHLVEVGAEVQDTPDGPRL 1406



 Score =  585 bits (1508), Expect = e-164
 Identities = 483/1540 (31%), Positives = 717/1540 (46%), Gaps = 123/1540 (7%)

Query: 3    AAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDR 62
            AAAP + DV  LSPLQEG+       +DGVD+Y  Q ++D+DGP+D + L  +   ++ R
Sbjct: 1463 AAAPGLTDVWPLSPLQEGMLFERAFDDDGVDVYQSQRILDLDGPLDAQRLHAAWNQVIAR 1522

Query: 63   HPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIA-----RSERRRPFDLSRG 117
            H +LRA+F +    + VQ++     +PW  RV   +  D  A       ++ + FD+++G
Sbjct: 1523 HDSLRASFHELASGQTVQVIVGQVDVPW--RVEDLSRLDETAVERLLAEDQAQRFDVTKG 1580

Query: 118  PALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX 177
            P LR++++ + G  + R++ T+HH+++DGWS  +   E   V                  
Sbjct: 1581 PLLRLLLIRL-GADRHRLVLTSHHVVLDGWSTPLILGE---VSTAYAGGHGASTPPSYKD 1636

Query: 178  YIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWA 237
            Y+ WL +QD     + W   L G  EP +V  +A      PG+    LP   T  L ++A
Sbjct: 1637 YLAWLNRQDEEKTRSAWQAELAGSDEPTIVDVDAPKTMVMPGQHAEWLPEEATRALTEFA 1696

Query: 238  GRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHY 297
              HGLT +T +  AWA+VL RL  R DVVFG+VVSGRP  +P VE +VG+FIN VPV   
Sbjct: 1697 RGHGLTPSTILQAAWALVLVRLAGRTDVVFGSVVSGRPADVPDVERIVGMFINTVPVRVR 1756

Query: 298  VSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPA 357
            + G++ V+A    +Q + SA+ +  ++ L EIQ+  G G +FD++ + EN P   A    
Sbjct: 1757 LDGSQPVLAIIQDLQARQSALTEHQHMGLPEIQKAAGTGAIFDTIVMIENYPHTAA---G 1813

Query: 358  TTPDGAQFLP-VEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVL 416
               DG   +  V   + T YPLT+   L                    AAE+  +++ VL
Sbjct: 1814 LGDDGGVVISGVATRTGTSYPLTMNVSLGDRLRINVSYRPDRIAGE-TAAEVARQVVRVL 1872

Query: 417  RQL---PDIGDG----TPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXX 469
             Q+   P +  G    T +        +  A G   A   P    +V E+F RQV     
Sbjct: 1873 EQVVAKPSLPVGRLGVTSESTRASVVEQWNATG--EAHGGP----SVVELFRRQV--GKS 1924

Query: 470  XXXXXXXXGVRH-TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXX 528
                    G R  +YA+L   + RLAG LA  GV     V +V+ R              
Sbjct: 1925 PDTVAVVDGERTLSYADLDRESDRLAGHLAGLGVRRGDRVGVVMERGADLFVALLGVWKA 1984

Query: 529  XXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRS 588
                +PV+V  P+ R+E ++  +S A+ +     + LV           P  V+ +  R+
Sbjct: 1985 GAAQVPVNVDYPAERIEQMLVGSSFAVCVE----AGLV-----------PEGVQPVDVRA 2029

Query: 589  AAA--PTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXX 646
                 P +       AYV++TSGSTG PKGV   + +V +   D                
Sbjct: 2030 TGGEPPALTVGAHDVAYVMYTSGSTGVPKGVAVPHGSVAALAGDPG----WSQGPDDCVL 2085

Query: 647  XXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMF 706
                HA+  S    W P+V   +G  + + +   + DA+RL E I+ G   +  T  +  
Sbjct: 2086 LHASHAFDASLVEIWVPLV---NGARVMVAEPGAV-DAERLREAISRGATTVHLTAGAFR 2141

Query: 707  VQLSAAGLLDHNLSVLALGGEAINTGLWDQLR-GLSQMAVYNCYGPTEMTVEXXXXXXKD 765
                 +      L  +  GG+A+      ++R     + V   YGPTE+T+       + 
Sbjct: 2142 AVAEESPESFIGLREILTGGDAVPLASVVRMRQACPDVRVRQLYGPTEITLCATWLVIEP 2201

Query: 766  YRKP----TIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFV 821
              +      IG   AG   YV D+ L+ V   V GELYL+GA LA GYVG  G T+ RFV
Sbjct: 2202 GAETGDTLPIGGPLAGRQAYVLDAFLQPVAPNVTGELYLAGAGLAHGYVGNSGPTSERFV 2261

Query: 822  ADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDA 881
            A+P   G+RMYRTGDL R    G   + GRAD+QVKIRGYRVE GEIEAAL   P V  A
Sbjct: 2262 ANPFASGERMYRTGDLARWTDQGELLFAGRADSQVKIRGYRVEPGEIEAALAEVPLVAQA 2321

Query: 882  AVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGK 941
               V+ ++D       + +      D  ++RA L  RLP +MVP  ++ L   P+  NGK
Sbjct: 2322 V--VVAREDLAGEKRLIAYVTGEALDPDEVRAHLAARLPEFMVPGMVLVLDSFPLTLNGK 2379

Query: 942  LDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSI 1000
                 +DR A  A             T+TER+LC+LF E L       DD  F  G DSI
Sbjct: 2380 -----IDRAALPAPEFTGRPAGREPRTETERLLCDLFAEILGLDRVGADDSFFELGGDSI 2434

Query: 1001 VAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSW 1060
            +++ L  +ARR+ +    + V    T   + A  + A  ++    D   G V   P++  
Sbjct: 2435 LSMRLAARARREDVVFGAKQVFEQKTPAGIAAVAERAGLTRADQTDG-IGEVLLTPVIKA 2493

Query: 1061 LYEYG--NYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTRE 1118
            L E+           V + +P  +    +   L  ++D HD LRS +    EGPRLV  +
Sbjct: 2494 LIEHDPKALSGSAQWVTVGVPDDLSADVLTAGLAAVIDTHDMLRSRIV---EGPRLVVAD 2550

Query: 1119 PAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADP 1178
               V A  V+ R+    G  DE+       AR    ++D +AG M+RA+           
Sbjct: 2551 RGTVEA--VVERV--DAGDLDEI-------ARDAAARLDATAGVMIRAVLV--------D 2591

Query: 1179 ANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASA 1238
            A  ++L AHHL VDVVSW  ++ DL AA  ++ AG  P++ P   SYRRW   +  +A+ 
Sbjct: 2592 AGKVVLAAHHLLVDVVSWRTLVADLQAACEAVAAGRTPELDPVDVSYRRWARTLGDQATL 2651

Query: 1239 PQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVD--VTERVLGAVRRD 1296
                 +   W  ++       G    DP  DT++T       +P    + ++   A    
Sbjct: 2652 R--TSELTTWTEILDGAPSRFG--ELDPKHDTFATAGRRSWTLPKGKALVDKATSAFH-- 2705

Query: 1297 QGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFP 1356
             GV E+LLA  A AV  WR          V+V +EGHGR   + + D + TVGWFT+  P
Sbjct: 2706 CGVHEVLLATLAGAVTHWR------GGTAVVVDIEGHGR-QPIDEMDLSRTVGWFTDIHP 2758

Query: 1357 VRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAV- 1415
            +RL   A  VD   A    VAA  LV  V  ++ A+P+ GL YG+LRY++     V A  
Sbjct: 2759 LRL--DATGVDTADAIAGGVAAGRLVKQVKENVRALPDGGLGYGMLRYLNAETGPVLAAL 2816

Query: 1416 -DPQIQFSYLGRLDLGGVADQPWSL--LTGPYLDALPIDPEPDLPLRFALNLSVFVGVTA 1472
              P+I F+YLGR          W +  ++G          E D PLR A+ +   V  T 
Sbjct: 2817 PKPEIGFNYLGRFSAQTGDAGLWQITGISGG-------GSEQDTPLRHAVEIDAVVTDTV 2869

Query: 1473 EGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD 1512
            +G +   N  W++ +   ++ + L   W   +  LA  ++
Sbjct: 2870 DGPEFTLNLTWAERILSEAEAESLAQAWLDMLTGLATHVE 2909



 Score =  456 bits (1173), Expect = e-125
 Identities = 354/1088 (32%), Positives = 513/1088 (47%), Gaps = 75/1088 (6%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            V AA P + D+  LSPLQEGL   H   E G D+Y+    + IDGP+D+   R S Q +L
Sbjct: 2934 VEAAVPSLVDIWPLSPLQEGLL-FHAADERGPDVYASMRTLAIDGPMDVARFRASWQVLL 2992

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSE-------RVATPAEFDSIARSERRRPFD 113
            DRHP LRA+F   +  + VQ +     L W E            AEFD +A       FD
Sbjct: 2993 DRHPALRASFHQLESGEAVQAIAREVTLDWQETDLSHLPEAEALAEFDRLAEQLHAERFD 3052

Query: 114  LSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXX 173
            L++ P LR+ ++ + G+ + +++FT+HHI  DGWSL +   ++L                
Sbjct: 3053 LTKAPQLRLHLVRI-GDRRHQLVFTSHHIAADGWSLPLILVDVLTAYEGGTLSPATSYRD 3111

Query: 174  XXXXYIVWLAKQDRSAALAGWMDYLRGVSEPL-MVAYEATAGQSKPGKTELLLPAADTAR 232
                ++ W+A+QD++AA   W   L G+ E   +V  E      +P +    L A  + R
Sbjct: 3112 ----FLAWIARQDKAAAREAWQRELAGLDEATHVVPPETIIAPIEPERVGFELDAELSKR 3167

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            L ++  RHG+T NT     WA+ L+RLT R  VVFG  V+GRP ++PGVE+ VGL++N +
Sbjct: 3168 LVEFTRRHGVTANTLFQGVWALHLARLTGREHVVFGAAVAGRPPEIPGVESSVGLYMNML 3227

Query: 293  PVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDD 352
            PV   ++G + V+   T +Q +  A+    ++ LSEI +  G+G  FD++ VFEN P   
Sbjct: 3228 PVRASLTGAQPVIDMLTDLQERQVALLSHQHIGLSEINQLAGQGAAFDTIVVFENYPPPP 3287

Query: 353  AIRPATTPDGAQFLPVEMESLT-HYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGER 411
                + +PD     P  + + T HYP+++ + +                  +  AE  E 
Sbjct: 3288 P--RSDSPDALVIRPTGIPNDTGHYPISMRAGVSGHGEFIYRPDV------VNRAEAEEM 3339

Query: 412  MLTVLRQL------PDIGDGT-----PDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMF 460
            +  +LR L      P I  G      P+   +      +    L   + P          
Sbjct: 3340 LAAILRALEQVVADPQIPVGRVGLIGPEQRRLVVDEWNQTDAPLTTETLPAL-------- 3391

Query: 461  ERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXX 520
             RQ                  +Y++L      LA  L   GV  E  V +++ RS     
Sbjct: 3392 VRQQAEQTPDAVAVQDAARSLSYSQLLGEVESLARLLVSLGVRRENRVGVLVERSAELAV 3451

Query: 521  XXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVP--TLALDD- 577
                       ++PVD   P  R+E ++  ++P + +       +V        L LD+ 
Sbjct: 3452 TLMGVTFAGGVFVPVDPDYPRERIEFMLANSAPEVLVCTKTTRAVVPAEFTGTVLVLDEL 3511

Query: 578  PAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYX 637
            PAA   +   S A       PE +AYVI+TSGSTG PKGV+  ++ +++    H ER+  
Sbjct: 3512 PAADPGVELPSVA-------PEDAAYVIYTSGSTGVPKGVLVAHSGLVNLGYAHIERMAV 3564

Query: 638  XXXXXXXXXXXXXHAWSLSFDASWQPM-VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQI 696
                            ++ FDA    + + LL G  + L DA  M     L + I    I
Sbjct: 3565 TASSRILQLS------AIGFDAIVSELYMTLLAGATLVLPDAASMPPRVTLGDAIRKAGI 3618

Query: 697  DMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV 756
              +  +PS+   L++   L   L  +  GGEA+   L D  R      V   YGPTE T+
Sbjct: 3619 THLTVSPSV---LASEDDLPDTLQTVLTGGEALPPALVD--RWSPGRRVIQAYGPTETTI 3673

Query: 757  --EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPG 814
                       + +  +G        YV D+ L+ VP GVVGELY++G  LARGY+GRPG
Sbjct: 3674 CSTMSAPLSPGHDQVPLGGPIYNVQHYVLDAYLQPVPPGVVGELYITGVGLARGYLGRPG 3733

Query: 815  MTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRG 874
            +T+ RFVA P  PG+RMYR+GDL R    G   + GR D QVK+RGYRVE  EIEA L  
Sbjct: 3734 LTSERFVASPFAPGERMYRSGDLFRWTREGQLMFAGRVDAQVKVRGYRVEPAEIEAVLIE 3793

Query: 875  QPGVHDAAVSVLRQ-QDRTSLVGFVVWQDNMHEDL-IKLRAGLTERLPSYMVPARIVTLP 932
             P V   AV+V R       LV +VV   +    L   LR    ERLP YM+PA  V+L 
Sbjct: 3794 HPEVAQVAVAVRRDGPGDKQLVAYVVPTADASSTLTAALRELAAERLPEYMMPAAFVSLE 3853

Query: 933  RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDD 991
            ++P+  NGKLD  AL      A+++  G      STD E  LC+LF + L      +DD 
Sbjct: 3854 KMPLTPNGKLDHKALQAPDFAAMSTKRG-----PSTDMEARLCDLFADVLGLEQVGVDDS 3908

Query: 992  LFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGA 1051
             F  G DSI ++ L  +ARRQGL + P  V    T  +L AA+   +  ++  A A   A
Sbjct: 3909 FFELGGDSITSMQLSARARRQGLELTPWQVFDEKTPERL-AAMVKELQVEEEVAAAPKPA 3967

Query: 1052 VRPLPMVS 1059
              PL  +S
Sbjct: 3968 ASPLLALS 3975


>tr|O87314|O87314_MYCSM Tax_Id=1772 (fxbC)SubName:
            Full=FxbC;[Mycobacterium smegmatis]
          Length = 4976

 Score =  630 bits (1626), Expect = e-178
 Identities = 501/1541 (32%), Positives = 730/1541 (47%), Gaps = 96/1541 (6%)

Query: 7    QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNL 66
            ++E+VL L PLQEG++      +   D Y +Q +  + GPVD E+LR S   ++ RH  L
Sbjct: 1132 EVEEVLPLLPLQEGMYFHSMFGDPATDTYRVQQIAQLSGPVDPEVLRTSLTVVMRRHQAL 1191

Query: 67   RAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLS 126
            RA+F +    +  Q++   + +P    V    + +SIA  E  RPF+L+  P +R +++ 
Sbjct: 1192 RASFNELTDGRVAQVI--WSDVPVQLTVVDTDDLESIAAEELARPFNLAEAPLVRYMLVR 1249

Query: 127  VPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX--YIVWLAK 184
            + G+   R++ T HHI+ DGWS  V F +++                      +I  +  
Sbjct: 1250 L-GDDDHRLVQTMHHIIADGWSYPVLFGDIVDHYNAAIGVGSAPQPITVTLRDHIETVTD 1308

Query: 185  QDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRHGLTL 244
            +DR AA   W   L G     +V     A   +       L +A T  + + A  HG+T+
Sbjct: 1309 RDRGAARQAWEQALAGAEPTALVPRPDGAPVGEHRSVVRRLDSARTPAVGRAARVHGVTV 1368

Query: 245  NTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEAV 304
             T +  AW ++L RL  R  VVFG+ VSGR   L G E++VGL IN +PV         +
Sbjct: 1369 GTVLHGAWGLMLGRLLGRNRVVFGSTVSGRGGDLAGTESIVGLLINTIPVPMSWEPHATL 1428

Query: 305  VAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDGAQ 364
             +    +Q Q SA+ D   + L+E+ R  G    FD++ + EN P   +    T P    
Sbjct: 1429 ASALIDLQDQQSALLDAQQMGLAELARLAGVREFFDTMVIVENFPSTSSAE-HTDPRAVA 1487

Query: 365  FLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPA--AEIGERMLTVLRQLPDI 422
            F         HYP++ V++                 P      AE  ER+LT   + PD+
Sbjct: 1488 FRGFTGTDSPHYPVSFVAYADDQLTVEIKYDAGVVTPEQAERYAERVERILTAFAETPDL 1547

Query: 423  GDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHT 482
                   +D+RT AE +     A+R  P    T+   F  +V               R T
Sbjct: 1548 ---PVSRIDLRTNAERQFTAGHASRPGP--GRTLGASF-AEVAATYPDAVAVSCGDTRLT 1601

Query: 483  YAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSA 542
            Y EL  RA  +A  LAE GVG E+ VA+ LPRS                Y+P+D+  P+A
Sbjct: 1602 YRELDDRAAAVAATLAERGVGAESRVAIALPRSADLIVAVLAVIKAGGTYVPIDIGAPAA 1661

Query: 543  RVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSA 602
            RV+ I+  ++P   +T+        T VP + L + A     +     APTV   P+ +A
Sbjct: 1662 RVQHILADSAPVCLLTDTAER---FTGVPHVILAEAAQ----NPARPQAPTVS--PDHAA 1712

Query: 603  YVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS-W 661
            YVI+TSGSTG PKGV  T+  V + FA     +Y                 S +FD S W
Sbjct: 1713 YVIYTSGSTGVPKGVEVTHRNVAALFAGTTSGLYDFGPDDVWTMFH-----SAAFDFSVW 1767

Query: 662  QPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQ-LSAAGLLDHNLS 720
            +    LL G  + + + +  RD +R V+ +A  ++ +++ TPS F   L A   L   L+
Sbjct: 1768 ELWGPLLHGGRLVVVEHDVARDPERFVDLLARERVTVLNQTPSAFYPLLEADARLRRQLA 1827

Query: 721  V--LALGGEAINT---GLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTAN 775
            +  +  GGEA++      W          + N YG TE  V               G+  
Sbjct: 1828 LRYVIFGGEALDVRRLAPWYANHESHSPRLVNMYGITETCVHVSHRALDTADTGAAGSVI 1887

Query: 776  AGTFG----YVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQR 830
             G       ++ D+ L+ VP GVVGE+Y++G Q+ARGY GRPG+TA RFVA+P    G+R
Sbjct: 1888 GGPLPGLRIHLLDNNLQPVPAGVVGEMYIAGGQVARGYTGRPGLTATRFVANPFDGAGER 1947

Query: 831  MYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQD 890
            +YR+GDL      G   Y+GR+D QVK+RGYR+E+GE+EAAL   PGV +AA  V R  D
Sbjct: 1948 LYRSGDLAMWTDAGELVYLGRSDAQVKVRGYRIELGEVEAALVTLPGVTNAAADV-RHDD 2006

Query: 891  --RTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALD 948
              R  L+G+VV       D+  LR+ L ERLP YMVP+ ++ L  LP+  NGK     LD
Sbjct: 2007 TGRARLIGYVVGD---ALDIGALRSTLAERLPDYMVPSVLLRLDVLPLTVNGK-----LD 2058

Query: 949  RLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPHIDDDLFLFGMDSIVAISLVHK 1008
            R A      V    A  A T T  +L  L  E L     ++DD F  G DSI+AI LV++
Sbjct: 2059 RAALPDPEPVEQAPAPVAGTGTASLLAGLCTEILGTTVGVEDDFFTAGGDSIIAIQLVNR 2118

Query: 1009 ARRQGLRVDPRMVLTATTIRQLGAAID----AAVD-SQDAPADADYGAVRPLPMVSWLYE 1063
            ARR+G+R+ P+ V    T   L + +D    AA D + D  A  D G V   P+V  L E
Sbjct: 2119 ARREGVRITPQQVFVHRTPAALASVLDTGSVAAPDATPDEDAGPDLGEVMLTPIVQRLAE 2178

Query: 1064 Y-GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAV 1122
              G   RF  + LLR P+G   + +E  +  ++  HD LR  L      P L + E  A 
Sbjct: 2179 LGGTVTRFNQSELLRTPAGATVARLETAINAVIARHDALRIRLHR--PAPMLWSLETTAA 2236

Query: 1123 RAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWF-RGTEHRADPANI 1181
             A   +TRI      D++L + +A  +    D++DP  G +V A+WF RGT    D    
Sbjct: 2237 -APVSITRIDAHGFDDEQLRTVIATESDAAADRLDPENGVVVVAVWFDRGT----DTQGR 2291

Query: 1182 LLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQV 1241
            LLL  HHLAVD VSW I+L DLA A+R   +G      P  TS R++   +   A     
Sbjct: 2292 LLLVVHHLAVDGVSWRILLDDLAEAYRQALSGQRVAPAPVTTSLRQYARTVNENAQHSSR 2351

Query: 1242 QDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAV--RRDQGV 1299
              + ++W   V  P   L +   D    T    +     +  + T  +L  V    +  V
Sbjct: 2352 LTEFEHWTE-VLAPGGEL-VATADVVTLTVGATRDHEIRLSTEDTAPLLTTVPAAANADV 2409

Query: 1300 RELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRL 1359
             E L+AA  +AV+ WR  R +   A ++++LE HGR     D D + TVGWFT+  PVRL
Sbjct: 2410 TETLVAALHLAVSRWRAARGEAADAPLVLSLERHGRDGWPDDVDLSRTVGWFTSIAPVRL 2469

Query: 1360 GAGAAAVDIEQAERDPVAAQDLVH---SVVSHLEAIPNDGLDYGLLRYVD--GVAELVDA 1414
                           P   +DL++   +V   L A P+ GL +G LRY +    A L   
Sbjct: 2470 ---------------PAPGEDLLNTLKAVKESLRAAPDGGLGFGQLRYCNPRTSAVLARL 2514

Query: 1415 VDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEG 1474
              PQ+ F+YLGR       D  W+  + P +DAL  +P PDL   + + ++     T +G
Sbjct: 2515 GTPQLLFNYLGRWAADACDD--WA--SAPEVDALRTEPNPDLGTPYLVEVNAICDDTVDG 2570

Query: 1475 TQLIGNWRWSDAVFERSDIDHLTGLW---QRGIAALAAGLD 1512
             +L     ++D   +   +  L  LW    R + +LA G D
Sbjct: 2571 PRLRATLTYADGELDEPSVAELGELWVAALRELGSLATGGD 2611



 Score =  562 bits (1448), Expect = e-157
 Identities = 462/1413 (32%), Positives = 657/1413 (46%), Gaps = 111/1413 (7%)

Query: 1    VTAAAP-QIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAM 59
            VT A P  +E +  LSPLQEG++   + A   V  Y +Q V D   PVD   LR +  A+
Sbjct: 2632 VTGAVPGNVETIWPLSPLQEGVYLQARYATAAV--YIVQNVFDFAEPVDTTALRTAYSAV 2689

Query: 60   LDRHPNLRAAFWDRDVPKPVQIV-------PVHAALPWSERVATPAEFDSIARSERRRPF 112
            + R+P LR+AFW  D+P+PV  +       P    L            + I   +R++ F
Sbjct: 2690 MARNPVLRSAFWADDLPQPVAAIVADPVCEPRVVDLGGLPATQVERRVEEITADDRQQTF 2749

Query: 113  DLSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLA---VXXXXXXXXXX 169
            DL+  P  R+ VL  P   + R+IF+ H +L+DGWS      EL A              
Sbjct: 2750 DLAAAPLARMTVLRTPD--RDRLIFSYHFLLLDGWSREQLLRELFAEYTAARGGAVAQLP 2807

Query: 170  XXXXXXXXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPG-KTELLLPAA 228
                    Y+ WLA+QDR  +   W + LR +  P ++  +A         + E LL  A
Sbjct: 2808 APTADFTDYLRWLARQDRDVSAREWSEALRDLEAPTLLVPDAVGTDPTLALRLEFLLSEA 2867

Query: 229  DTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLF 288
            DTA L   A   G+TLN  +  A A+VL+  T R DVVFG+ V+GRP  L G+++++GLF
Sbjct: 2868 DTAALTAAARSAGVTLNALISTALAMVLAYETGRDDVVFGSTVAGRPTDLDGIDSVIGLF 2927

Query: 289  INAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQR--EHGRGPLFDSLFVFE 346
            +N VP    ++    V      VQ     + D  YL L +IQR    G GPLFDSL+V +
Sbjct: 2928 LNTVPTRVRLAPHRTVADTMRAVQSDRLRLMDHEYLGLGDIQRAVSTGGGPLFDSLYVLQ 2987

Query: 347  NAPIDDAIRPATTPDGAQFLPVEMESL--THYPLTVVSHLRXXXXXXXXXXXXXXXPYLP 404
            N   DD      T   AQ+  V  +S+  +HYPLT V+                  P + 
Sbjct: 2988 NFLDDDTF----TDMEAQYGIVGHDSIDASHYPLTWVAS-----PGRRLWMKLEYRPDVV 3038

Query: 405  AAEIGERMLTVLRQ-LPDIGDGTPDD-----LDIRTAAELKAHGLLAARSAPTFDTTVWE 458
              +  + +L  LRQ L  +G G         L +   A+ K     A        + +  
Sbjct: 3039 ERDRAQGLLDRLRQVLLQVGTGVERPSAALTLPLPAEADHKRTRDAATEHDLPHASVLDL 3098

Query: 459  MFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS 518
            + ER VQ             V   YAEL AR  RLA  L   G+GPE  VAL +PRS  +
Sbjct: 3099 LAERAVQSGDLTALVCGGEFV--DYAELLARVNRLAWVLRSRGIGPEDTVALAVPRSIDA 3156

Query: 519  XXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVG--TAVPTLALD 576
                         YLP+++  P  R+  ++  A P   +     +Q +    + P   LD
Sbjct: 3157 VVALFAVLRAGAAYLPLELDYPDERLAVMLGDAEPVRVLVTGATAQRIARVASAPLTVLD 3216

Query: 577  DPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVY 636
             P   + ++R  +        P+Q AYVI+TSGSTG+PKGVV  +  + +   +H E ++
Sbjct: 3217 APDTCDELARARSDWDGYSPHPDQPAYVIYTSGSTGKPKGVVTPHRGLTNMHLNHREAIF 3276

Query: 637  XXXXXXXXXXXXXX-HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQ 695
                           H  S SFD SW+ ++ L+ GHE+H+ D    RDA  LV      +
Sbjct: 3277 APTIARAHGRRLKIAHTVSFSFDMSWEELLWLIQGHEVHICDEVLRRDATSLVRYCHDHR 3336

Query: 696  IDMIDTTPSMFVQLSAAGLLD---HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPT 752
            ID+I+ TP+    L   GLL+   H   ++ LGGEA++T +W++LR   +   YN YGPT
Sbjct: 3337 IDVINVTPTYAALLFEEGLLEQAGHPPVLVLLGGEAVSTTVWNRLRDSERWYGYNLYGPT 3396

Query: 753  EMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGR 812
            E T+        D   PT+GT    T  ++ D+ LR VPDGV GELY++GA LARGY+G+
Sbjct: 3397 EYTINTLGGGTDDSATPTVGTPIWNTRAHILDNWLRPVPDGVPGELYIAGAGLARGYLGQ 3456

Query: 813  PGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
            PG+TA+RFVA+P  PG RMYRTGDLV R +     ++GR D QVKIRGYRVE+G+IEAAL
Sbjct: 3457 PGLTASRFVANPFEPG-RMYRTGDLVVRRADDNIDFLGRTDDQVKIRGYRVELGDIEAAL 3515

Query: 873  RGQPGVHDAAVSVLRQQDRTS-LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTL 931
               P  H   V        +S LV +VV      + L  LR  LT  LP+YMVP  + TL
Sbjct: 3516 VSTPASHRPRVIARPDTAGSSRLVAYVVPTTENPDVLDDLRMHLTATLPAYMVPTAMATL 3575

Query: 932  PRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP----H 987
              +P+  NGKLD  AL     D       G   +     E  LC +F E L         
Sbjct: 3576 TEIPLTDNGKLDTRAL----PDVAPIGRHGAGRAPQGAVEATLCSVFAEVLGLDGPDGLS 3631

Query: 988  IDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAID----------- 1035
            +DDD F  G  S++ I L+ + R + G  +    V  + T+  L   +            
Sbjct: 3632 VDDDFFDLGGHSLLTIRLISRIRSELGAELTLGDVFNSRTVAALARHVTADEGDNRRPRL 3691

Query: 1036 -AAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLL 1094
             A    Q  PA     A R + M+  L E G+   + + ++ R+   +D  ++   L  +
Sbjct: 3692 VAGPRPQHIPASP---AQRRMLMLDRLGETGS--AYNYPLVFRVRGALDVDALRDALTAV 3746

Query: 1095 LDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLP--EGSDDELASAVAHAARVV 1152
            +D H+ LR++  +              V  + +L R T P    SD         A  +V
Sbjct: 3747 VDRHEALRTVFDDRD-----------GVYHQRILPRGTQPPLHVSDCPEHELATRADALV 3795

Query: 1153 TDQIDPSAGAMVRAIWFR-GTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQ 1211
              + D +    +R    R G E   D   ++LL  HH+A+D  S  + L DL AA+ + +
Sbjct: 3796 EHRFDLTGEIPLRVDVLRSGPE---DHTVVMLL--HHIAIDEWSDAVFLADLDAAYAAHR 3850

Query: 1212 AGTPPKILPEFTSYRRWCELMWHRASAPQVQD-QRDYW-AALVREPDP-ALGLRYPDPTR 1268
            AGT   +      Y      +W R    Q+ D QR++W  AL   PD  AL    P P R
Sbjct: 3851 AGTAAPLPEPVVQYAD--HTLWQRDVLAQLGDRQREFWRTALAGAPDELALPADRPRPAR 3908

Query: 1269 DTWSTLQLTRAAIPVDVTERVLGAVRR---DQGVRELLLAATAMAVASWRRVRAQDPAAG 1325
             T +        + V++T     A+RR   D+ V  L++   A+AV   R     D   G
Sbjct: 3909 PTGA-----GGTLDVEITAETASALRRLAADKQVSMLMVLHAAVAVLIHRLGAGDDIVVG 3963

Query: 1326 VLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
              VA    GR DA LD    + VG F N   +R
Sbjct: 3964 TPVA----GRDDAALD----DVVGLFVNTVVLR 3988



 Score =  511 bits (1317), Expect = e-142
 Identities = 349/953 (36%), Positives = 473/953 (49%), Gaps = 63/953 (6%)

Query: 585  SRRSAAAPTVDRR----------PEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAER 634
            +RR A AP   RR          PE  AY+I+TSGSTG PKGV+   A + + + +H E 
Sbjct: 181  TRRYARAPADRRRTRGFRVRQHAPEHPAYLIYTSGSTGRPKGVLTGYAGLTNMYFNHREA 240

Query: 635  VYXXXXXXXXXXXXXX--HAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIA 692
            ++                H  S SFD SW+ +  L++GH++H+ D E  RDA  LV    
Sbjct: 241  IFAPTVARAGSAEQLRIAHTVSFSFDMSWEELFWLVEGHQVHVCDEELRRDAPALVAYCH 300

Query: 693  IGQIDMIDTTPSMFVQLSAAGLLD---HNLSVLALGGEAINTGLWDQLRGLSQMAVYNCY 749
              +ID+I+ TP+    L  AGLLD   H   ++ LGGEA+  G+W  LR     A YN Y
Sbjct: 301  RHRIDVINVTPTYAHHLFDAGLLDDGAHTPPLVLLGGEAVGDGVWSALRDHPDSAGYNLY 360

Query: 750  GPTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGY 809
            GPTE T+        D   PT+G     T GY+ D+ALR VPDG VGELY++G  LA GY
Sbjct: 361  GPTEYTINTLGGGTDDSDTPTVGQPIWNTRGYILDAALRPVPDGAVGELYIAGTGLALGY 420

Query: 810  VGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGG--YAYVGRADTQVKIRGYRVEVGE 867
              R G+TAA  VADP  PG RMYRTGDLVRR         Y+GR D QVKIRGYRVE+GE
Sbjct: 421  HRRAGLTAATMVADPYVPGGRMYRTGDLVRRRPGSAELLDYLGRVDDQVKIRGYRVELGE 480

Query: 868  IEAALRGQPGVHDAAVSVLRQQDRT----SLVGFVV---WQDNMHEDLIKLRAGLTERLP 920
            IE+ L    GV   AV V R         +L  +V+   W       +  LR  L   LP
Sbjct: 481  IESVLTRADGVARCAV-VARATGANPPVKTLAAYVIPDRWPAEDAAFITGLRDHLARVLP 539

Query: 921  SYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEE 980
             YMVP R   +  LP+  NGKLD  AL         + + GT  +  TD E  L E+   
Sbjct: 540  GYMVPTRYGIVDTLPLTINGKLDVAALPE-----PIAATSGTGRTPRTDREATLLEIVAS 594

Query: 981  QLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVD 1039
             L      +DDD F  G DSI +IS+  +AR+ GL + PR V    TI  L A+ D    
Sbjct: 595  VLGIDGIGVDDDFFTLGGDSISSISVCGRARKAGLNITPRDVFRRRTIAALAASADTTQT 654

Query: 1040 SQDAPADADYGAVRPLPMVSWLYEYGN-YRRFTHTVLLRLPSGIDRSSIELMLQLLLDGH 1098
             +  P D   GA+   PM++   +       F   ++L  P+GI    ++ +LQ ++D H
Sbjct: 655  PESGP-DTGTGAITATPMLAETAQANTPLTNFYQAMVLATPAGITAHEVQRVLQTVVDAH 713

Query: 1099 DTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDP 1158
              LR+ L  T  G  L   +  A     V +     +  + E A+A A        ++DP
Sbjct: 714  AMLRARLVTTATGWTLTVPDQTAAIGLTVRSGALTSDCVEAEKAAAAA--------ELDP 765

Query: 1159 SAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKI 1218
             AG MVRA+WF   E     +  LLL  HHL +D VSW I+  DL+ AW  L AG     
Sbjct: 766  RAGNMVRAVWFDAPE----ASGQLLLVIHHLVIDGVSWRILSEDLSRAWNDLAAGRDVAA 821

Query: 1219 LPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTR 1278
                TS+  W   +  R       D+ +YWA ++  PDP LG R PDP  DT  T++   
Sbjct: 822  DAVPTSFHTWANALAQRT----FDDESEYWADVLATPDPDLGSRPPDPAIDTADTVRSHE 877

Query: 1279 AAIPVDVTERVLGAV--RRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRA 1336
              +  DVTE +L +V      GV ++LL   A+A+A WR  R        +++LEGHGR 
Sbjct: 878  VTLASDVTEALLTSVPAAMHGGVNDVLLTGLAVALAQWRADRGHSQNTAAVISLEGHGRE 937

Query: 1337 DAVL--DTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPN 1394
              ++  D D + TVGWFT+ +PVR+  G    D  ++    +AA     +V   L A+PN
Sbjct: 938  SDLVAADLDLSRTVGWFTSIYPVRIDPGPLEWDTVRSAGAELAA--AAKAVKEQLRAVPN 995

Query: 1395 DGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEP 1454
             GL YG+LR++ G    +D   PQI F+YLGR   G   D  W  + G  + AL    +P
Sbjct: 996  RGLGYGVLRHLHGA---LDGTPPQILFNYLGRFTGGSGND--WRPVAG--IGALTEGVDP 1048

Query: 1455 DLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAAL 1507
              P   +L ++       +GT L     W   + +  D+  L  +W   + AL
Sbjct: 1049 SNP-AMSLEINALAEERPDGTVLSMTLAWPGGLLDADDVSELGSMWADVLVAL 1100



 Score =  293 bits (751), Expect = 1e-76
 Identities = 317/1105 (28%), Positives = 466/1105 (42%), Gaps = 100/1105 (9%)

Query: 4    AAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRH 63
            A P+ + + A SP Q  +  L +L E G   Y+   V  + G +D++ LR +  A++DRH
Sbjct: 3693 AGPRPQHIPA-SPAQRRMLMLDRLGETG-SAYNYPLVFRVRGALDVDALRDALTAVVDRH 3750

Query: 64   PNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVV 123
              LR  F DRD     +I+P     P         E  + A +     FDL+    LRV 
Sbjct: 3751 EALRTVFDDRDGVYHQRILPRGTQPPLHVSDCPEHELATRADALVEHRFDLTGEIPLRVD 3810

Query: 124  VLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYI---V 180
            VL   G     ++   HHI +D WS AVF  +L A                   Y    +
Sbjct: 3811 VLR-SGPEDHTVVMLLHHIAIDEWSDAVFLADLDAAYAAHRAGTAAPLPEPVVQYADHTL 3869

Query: 181  W-------LAKQDRS---AALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADT 230
            W       L  + R     ALAG  D L   ++    A    AG    G  ++ + A   
Sbjct: 3870 WQRDVLAQLGDRQREFWRTALAGAPDELALPADRPRPARPTGAG----GTLDVEITAETA 3925

Query: 231  ARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFIN 290
            + LR+ A    +++   +  A AV++ RL    D+V GT V+GR D    ++ +VGLF+N
Sbjct: 3926 SALRRLAADKQVSMLMVLHAAVAVLIHRLGAGDDIVVGTPVAGRDDA--ALDDVVGLFVN 3983

Query: 291  AVPVVHYVSGTEAVVAQCTQVQRQSSAM---RDVSYLSLSEI---QREHGRGPLFDSLFV 344
             V +   ++G         +V+    A    +D+ +  L E     R  GR PLF+    
Sbjct: 3984 TVVLRADLAGNPTFTELLDRVRTADLAAFAHQDLPFDHLVEELNPPRVAGRNPLFNLFVG 4043

Query: 345  FENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLP 404
            +      D+       +  +  P    ++     T+V H                  Y  
Sbjct: 4044 YHLRSGTDSDMFGLPTEWTE--PAVSAAMFDLGFTLVDH-------GGDESASITAEYAA 4094

Query: 405  AAEIGERMLTVLRQLPDIGDGTPDDLDIRTAA-ELKAHG----LLAARSA---PTFDTTV 456
                   + T+ R+L  + D    D + R  A +L A G    L+   +A   P    T+
Sbjct: 4095 DLFDASTVHTLARRLVALLDHVVADAETRIGALDLLAPGEHDTLVVEHNATEHPLEPITL 4154

Query: 457  WEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSE 516
              +  RQ                  +Y +L   + RLA  L+  G  P TVV + LPRS 
Sbjct: 4155 GALVSRQATSTPHATALRYEES-ELSYRDLDGWSDRLAAHLSARGAAPGTVVGVSLPRSV 4213

Query: 517  RSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALD 576
                           +LP+D   P  R+E +V  A P                     LD
Sbjct: 4214 ELVVALVAVAKSGAAFLPLDPEYPRERLEYMVSDARPITV------------------LD 4255

Query: 577  DPAAVE-SISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERV 635
            DP AV  S        P +D  P   AYV++TSGSTG PKGV   +A +++  A   +  
Sbjct: 4256 DPDAVRRSRGEPDGELPRID--PAAWAYVLYTSGSTGRPKGVAVAHAGIVNRIAC-LQHA 4312

Query: 636  YXXXXXXXXXXXXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIG 694
            Y                  +SFD S W+    L  G  + +      R+   L   IA  
Sbjct: 4313 YPLGTDDRMLVKTP-----ISFDTSVWEVFWPLSVGATLVVARPGGHREPAYLAAMIAEQ 4367

Query: 695  QIDMIDTTPSMF-VQLSAAGLLDHNLSVLALGGEAINTGLWDQL-RGLSQMAVYNCYGPT 752
             +  +D  PSM  V L        +L+ + +GGEA+ T L  +       + ++N YGPT
Sbjct: 4368 CVTAVDFVPSMLEVFLDEVAGTCASLTRVTVGGEALTTELAARFAEAFPGVPLHNLYGPT 4427

Query: 753  EMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGR 812
            E  V+       D     +G        YV D  L  VP G  GELYL+G QLA GY+ R
Sbjct: 4428 EAAVDVLGWTA-DGGPVALGVPGWNVRAYVLDDYLNPVPAGAPGELYLAGIQLADGYLHR 4486

Query: 813  PGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
              +TAARFVA P   G RMYRTGD+VR  + G   Y+GR+D Q+K+RG R+E GEIE  L
Sbjct: 4487 GALTAARFVASPFDQGARMYRTGDVVRWRADGQLEYLGRSDDQIKLRGVRIEPGEIETVL 4546

Query: 873  RGQPGVHDAAVSVLRQQDRTSLVGFVV---WQDNMHEDLIKLRAGLTERLPSYMVPARIV 929
               P V  ++V V+ +  R  L+ + V    + +  E   +LR      LPS+MVP+  V
Sbjct: 4547 ATHPAV--SSVRVIARGGR--LMAYYVPAGVEASAGELRDELREHAAAALPSHMVPSGFV 4602

Query: 930  TLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHI 988
             L   P+  +GKLD  AL   A     + +G    + +T+ +  LCELF + L   V  I
Sbjct: 4603 ALTEFPLTPSGKLDRRALPEFA----GATAGVPGRAPTTERQHRLCELFSDVLGLEVTGI 4658

Query: 989  DDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPA-- 1045
            DDD F+ G  S++ + L    RR+  + V    ++ + T+  +   +DAA  S D+ A  
Sbjct: 4659 DDDFFVLGGHSLLLVRLAAALRREFSVDVPVADLMVSPTVADIDQRLDAAGSSVDSLAPV 4718

Query: 1046 --------DADYGAVRPLPMVSWLY 1062
                    DA    V P   +SW +
Sbjct: 4719 LPFRASGTDAPLFCVHPASGLSWQF 4743


>tr|Q45R83|Q45R83_STRFR Tax_Id=1906 (lptC)SubName: Full=Peptide
            synthetase;[Streptomyces fradiae]
          Length = 5246

 Score =  621 bits (1601), Expect = e-175
 Identities = 530/1577 (33%), Positives = 725/1577 (45%), Gaps = 124/1577 (7%)

Query: 11   VLALSPLQEGLFALHQLAEDGVD-LYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAA 69
            +L LS  Q+ L+ LH +  DG    Y++   + + GP+D+  L  + + ++ RH  LR  
Sbjct: 2    MLPLSLAQQRLWFLHTM--DGPSSTYNIPTALRMTGPLDVTALGEALRDVVRRHETLRTV 59

Query: 70   FWDRDVPKPVQIVPVHA-ALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSVP 128
            F D        ++P    A+  +   +T  E  +    E    FDL+R   +R   L V 
Sbjct: 60   FPDTGDGARQHVLPADGTAVELAVTRSTEHELPAALAHEAGHAFDLAREVPIRAR-LFVL 118

Query: 129  GETKRRMIFTAHHILVDGWS---LAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVW---- 181
            GE +  +    HHI  DGWS   LA       A                   Y +W    
Sbjct: 119  GEREHVLCLVIHHIASDGWSRTPLARDLATAYAARGAGHAPRWEELPVQYGDYTLWQREL 178

Query: 182  LAKQDRSAAL-----AGWMDYLRGVSE----PLMVAYEATAGQSKPGKTELLLPAADTAR 232
            L  QD   +L     A W   L G+ +    PL       AG  +       LP A   R
Sbjct: 179  LGSQDDPESLLSRQTAYWKQRLAGLPDAIELPLDRPRPPIAGH-RGDTVPFTLPPATHER 237

Query: 233  LRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAV 292
            +   A RHG T    V  A A +LSRL    D+  GT V+GR D    +E ++G F+N +
Sbjct: 238  VAALAARHGATTFMVVQAALAGLLSRLGAGTDIPLGTPVAGRTDA--ALEGLIGFFVNTL 295

Query: 293  PVVHYVSGT---EAVVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSLFVFE 346
             +    SG    + +V +       + A +DV +  L E    +R   R PLF      +
Sbjct: 296  VLRTDTSGNPTFDELVERARACALDAYAHQDVPFERLVETLAPERSLARHPLFQVSLSLQ 355

Query: 347  NAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPY---- 402
            +A    A+      +G +  P++              L                 Y    
Sbjct: 356  HATDHTALL-----NGLEIAPLDTGWRAAKFDLSFDLLEKRGPDGRPDGIAGTVEYSTDV 410

Query: 403  LPAAEI---GERMLTVLRQLPDIGDGTPD----DLDIRTAAELKAHGLLAARSAPTFDT- 454
            L AA +   GER++ +L    + G   P+     +D+ +A E +   L    + P  D  
Sbjct: 411  LDAATVRGLGERLVRLL----EAGTAAPEARLLSIDLLSAEE-RRRVLEEFAAEPAADEP 465

Query: 455  ------------TVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGV 502
                         V + F RQ               V  T+AE  AR  RLA  L   G 
Sbjct: 466  AAAEPAADEGLEAVCDTFARQAAATPEAPAVVGGP-VALTFAEADARVSRLARLLISRGA 524

Query: 503  GPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITE-AD 561
            GPE  VA+ L R+                ++P+D   P  R+ ++ R  +P L + E A 
Sbjct: 525  GPEVRVAVCLDRNALWPTTVLAVLRSGAVHVPLDPRSPHERLAAVERDVAPLLVLAERAT 584

Query: 562  YSQLVGTAVPTLALDDPAAVESISRRSAAAPT-VDRR----PEQSAYVIFTSGSTGEPKG 616
             + +   A P L LDDP+   +I        T  DR     P  +AYVI TSGSTG PKG
Sbjct: 585  EAAVADLAAPVLVLDDPSTEAAIDALDPGPVTDADRTAPLLPGHAAYVIHTSGSTGRPKG 644

Query: 617  VVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLF 676
            V   +  +      H    +              H  S SFDASW P++ ++ GHE+H+ 
Sbjct: 645  VTVDHRGLSRLLQAHRRVTFSRIRPSAGGPGRAAHVSSFSFDASWDPLLAMVAGHELHMI 704

Query: 677  DAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNL---SVLALGGEAINTGL 733
            D +   D   +V      +ID +D TP+ F  L  AGLL+      S++ALGGEA++  L
Sbjct: 705  DEDLRFDPPGVVAYFRDRRIDYVDLTPTYFRSLLDAGLLEEGFPCPSLVALGGEAMDGEL 764

Query: 734  WDQLRGLS-QMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPD 792
            W++LR  + ++   N YGPTE  V+       D    TIG        YV D+ LR VP 
Sbjct: 765  WERLRAAAPRVTAMNTYGPTETAVDAVVTVLGDLPPGTIGRPVPRWRAYVLDAGLRPVPP 824

Query: 793  GVVGELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGR 851
            GV+GELYL+G  +ARGY+G+  +TA RFVA P  +PG+RMYRTGDL R L  G   YVGR
Sbjct: 825  GVLGELYLAGPGVARGYLGQHALTAERFVACPFGKPGERMYRTGDLARWLPDGHLVYVGR 884

Query: 852  ADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRT-SLVGFVVWQDNMHEDLIK 910
             D QVKIRG+R+E GE+EAALR   GV  AAV+V      T  LVG+VV   +  +  ++
Sbjct: 885  GDEQVKIRGFRIEPGEVEAALRELEGVAAAAVTVREDTPGTRRLVGYVVGTPDADDARLR 944

Query: 911  ---LRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSAS 967
               + A L +RLP ++VP+  V L  LPVN +GKLD  AL   A D     +G       
Sbjct: 945  PAEVLARLRDRLPDHLVPSAFVRLRELPVNTSGKLDRAALP--APDPADFPAGR---RPR 999

Query: 968  TDTERVLCELFEEQLNA-VPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATT 1026
            T  ER +C LF E L A    IDDD F  G DSI++I LV  ARR GL    R V    T
Sbjct: 1000 TALEREVCALFAEVLGAGSVGIDDDFFGRGGDSILSIQLVGSARRAGLTFTVRQVFELRT 1059

Query: 1027 IRQLGAAIDAAVDSQDAPADADYG-AVRPLPMVSWLYEY----GNYRRFTHTVLLRLPSG 1081
                 AA+ AA    DA  D D   AV PLP++  + E     G    +  +V+L  P  
Sbjct: 1060 ----PAALAAAARRTDAAGDEDPALAVGPLPLLPVVAETLAAGGPVHSYNQSVVLASPPD 1115

Query: 1082 IDRSSIELMLQLLLDGHDTLRSILTETPEGP----RLVTREPAAVRAEDVLTRITLPEGS 1137
                 +   LQ LLD HD LR +      GP     L   E   V AE  L RI     S
Sbjct: 1116 AAPDDVRDALQALLDRHDALR-VHAAPAAGPGRLWDLRVEEAGTVAAERCLRRIDATGMS 1174

Query: 1138 DDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWH 1197
            D+ELA A A  A      +DP AGA+V A+WF     R D    L+L  HHLAVD VSW 
Sbjct: 1175 DEELARAQAAEAVTARACLDPLAGALVSAVWF----DRGDRPGRLVLVIHHLAVDGVSWR 1230

Query: 1198 IMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDP 1257
            I+LGDL  AWR+L+AG  P++    TS R W   +  RA+ P V  Q D+W A + +  P
Sbjct: 1231 ILLGDLREAWRALRAGRRPELPRTGTSLRTWATRLTERATDPAVTAQLDHWTATLAD-GP 1289

Query: 1258 ALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRR--DQGVRELLLAATAMAVASWR 1315
            A G R  D TRDT +T  +    +P  +T  +LG        GV +LLL A A+AVA WR
Sbjct: 1290 APGSRPLDRTRDTVATSAVLSGELPASLTTDLLGPAPAAFRAGVNDLLLTAFALAVAHWR 1349

Query: 1316 RVRAQDPAAGVLVALEGHGRADAVL-DTDTTNTVGWFTNAFPVRLGAG-AAAVDIEQAER 1373
                 +  A VLV LE HGR + ++   D + TVGWFT+  PVRL AG   A D+  AER
Sbjct: 1350 ----GEEDAPVLVDLESHGRTEELVPGADLSRTVGWFTSVHPVRLAAGRVTAADL--AER 1403

Query: 1374 DPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYV--DGVAELVDAVDPQIQFSYLGRLDL-G 1430
             P A  D +  +   L A+P+ GL +GLLR++  D    L      +  F+YLGR     
Sbjct: 1404 AP-AVGDAIKRIKEQLRAVPDGGLGHGLLRHLNPDTAPRLRGLARARFGFNYLGRFAAEQ 1462

Query: 1431 GVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFER 1490
            G  +  W     P L + P    PD PL   + ++V      +G +LI  W ++  +   
Sbjct: 1463 GAGEDSW-----PLLGSGPAGQHPDTPLDHEIEVNVVTAEGPDGPRLITRWTYATGLLTE 1517

Query: 1491 SDIDHLTGLWQRGIAAL 1507
             ++  LT  W   + A+
Sbjct: 1518 EEVRRLTRSWSLALHAV 1534



 Score =  501 bits (1291), Expect = e-139
 Identities = 491/1575 (31%), Positives = 666/1575 (42%), Gaps = 144/1575 (9%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            L LS  Q  L+ + QL E     Y++ + + + GP+D+  LR +   ++ RH +LR  F 
Sbjct: 3704 LPLSHAQRRLWFVRQL-EGPSATYNVPWALRLTGPLDVAALRAALGDVVARHESLRTVFA 3762

Query: 72   DRDVPKPVQIVPVHAALPWSERVATPAE-FDSIARSERRRPFDLSRGPALRVVVLSVPGE 130
            + +      ++      P S  V T  +    + R      F L   P LR  + +   E
Sbjct: 3763 EDEHGPHQVVLSADGPAPLSGPVRTDEDALPRLLREAADHAFRLDAEPPLRAHLFATAPE 3822

Query: 131  TKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAKQDR--- 187
                ++   HHI  D WS      +L A                   Y  +   Q     
Sbjct: 3823 D-HTLLLVMHHIATDAWSQRPLIADLAAAYAARHAGRVPTLPPLPVAYADYALWQQARLG 3881

Query: 188  ---------SAALAGWMDYLRGVSEPLMV-------AYEATAGQSKPGKTELLLPAADTA 231
                     SA LA W D L G  E L +       A  +  G S P    L +P     
Sbjct: 3882 DEREKDSALSAQLAYWRDALAGSPEELALPADRPRPAVPSHRGDSVP----LTVPPELHG 3937

Query: 232  RLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINA 291
            R+ + A     T    V  A A +L+RL    DV  G+ V+GR D    +E +VG F+N 
Sbjct: 3938 RVVELAREFRATPFMVVHAALAALLTRLGAGTDVPIGSPVAGRVDD--ALEDLVGFFVNT 3995

Query: 292  VPVVHYVSGTEAVVAQCTQVQRQ---SSAMRDVSYLSLSEI---QREHGRGPLFDSLFVF 345
            + +    SG         +V+     + A +D+ +  L E+   +R   R PLF     +
Sbjct: 3996 LVLRTDTSGDPTFGELLERVRATDLGAYAHQDLPFERLVELRDPERSLARHPLFQVSLNY 4055

Query: 346  ENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYL-- 403
            + A    A   A   DG         +++  PL V +                  P    
Sbjct: 4056 DTAETARARDAAPELDGL--------TVSGRPLGVTTSKFDLTFALTETRAHDGGPAGLR 4107

Query: 404  -------------PAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAAR--- 447
                          A  + ER   VL+          D +D+    E     LL      
Sbjct: 4108 GALEYSTDLFDRGTAERLAERFARVLQAAVAAPGTRLDQIDVLLPGE---RALLEGEWSR 4164

Query: 448  -----SAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRH-TYAELHARACRLAGELAEHG 501
                  APT D    ++FE Q              G R  +YAEL+ RA RLA  LA  G
Sbjct: 4165 PEPGPVAPTDDARFPDLFEAQAARTPHAPAVRD--GDRELSYAELNDRANRLARFLAARG 4222

Query: 502  VGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITE-A 560
             GPE  VA++LPR                 Y+P+D  LP+ R+  ++  A P L +   A
Sbjct: 4223 AGPEDTVAVLLPRGPELITALVAVQKAGAAYVPMDAELPAERIAHMLENARPVLVLAHTA 4282

Query: 561  DYSQLVGTAVPTLALDDPAAVESISRRSAAAPT-VDRRPEQS----AYVIFTSGSTGEPK 615
                L   A P + LD PA   +++       T  DRR   +    AYV++TSGSTG PK
Sbjct: 4283 TQDALPEGAGPVVRLDAPAIEAALAGLDGGDCTDADRRAPATHHDPAYVVYTSGSTGTPK 4342

Query: 616  GVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHL 675
            GVV    ++ ++    A R                 A+ L+    + P++    G  I +
Sbjct: 4343 GVVVEQRSLAAFLVRSAARYRGAAGTALLHGSP---AFDLTVTTLFTPLIA---GGCIVV 4396

Query: 676  FDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWD 735
             D +         E  A  + D++  TPS    L          + L +GGE +      
Sbjct: 4397 ADLDAP-------ERDAPARPDLLKVTPSHLALLDTIASWATPAADLVVGGEQLTASRLA 4449

Query: 736  QLRGLS-QMAVYNCYGPTEMTVEXXXXXXKDYRKPT-----IGTANAGTFGYVFDSALRM 789
            +LR     M V+N YGPTE TV       +    P      IG   AG   +V D  LR 
Sbjct: 4450 RLRRAHPDMRVFNDYGPTEATVSCADFVLEPGDAPPTDTVPIGRPLAGHRLFVLDDRLRP 4509

Query: 790  VPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAY 848
            VP  V GELY+SG  +ARGY+GRPGMTA RFVA P   PG+RMYRTGDL RR + G   Y
Sbjct: 4510 VPANVPGELYVSGVGVARGYLGRPGMTAERFVACPFGEPGERMYRTGDLARRRADGNLEY 4569

Query: 849  VGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDL 908
            +GR D QVK+RG+RVE GEIE AL  +P +  AAV VLR +    L+ +V        D 
Sbjct: 4570 LGRRDGQVKVRGFRVETGEIETALLDRPEIGQAAV-VLRGE---RLLAYVAAPPERF-DP 4624

Query: 909  IKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSAST 968
              LR  L  RLP YMVPA  V L  LP+   GKLD  AL      A           A  
Sbjct: 4625 DALRQALASRLPRYMVPAAFVRLDALPLAPGGKLDHRALPEPPAPADAPHGSRPPRDA-- 4682

Query: 969  DTERVLCELFEEQLN-AVPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTI 1027
              E VLCE F E L  A    DDD F  G DSI +I LV + R  G R+  R +    T 
Sbjct: 4683 -WEGVLCEAFGEVLGIAEVGADDDFFALGGDSIGSIRLVGRVRAAGGRMTVRDIFEQRTP 4741

Query: 1028 RQLGAAIDAAVDSQDAPADADYGAVRPLPMVSWLYEYGN-YRRFTHTVLLRLPSGIDRSS 1086
              L         + +       G V P P+ SWL E G     +  +VLLR+P+  D + 
Sbjct: 4742 AALAGRSRPGGPATEVLGGRGTGPVEPTPISSWLAELGGAVDGYNQSVLLRVPAEADAAV 4801

Query: 1087 IELMLQLLLDGHDTLRSILTETPEGP-RLVTREPAAVRAEDVLTRITLPEGSDDELASAV 1145
            +   LQ LLD HD LR +  E  +G  R+   E  AV A  VL R+        EL   V
Sbjct: 4802 VTGALQTLLDHHDALR-MRAEPEDGHWRMEIAEAGAVDAATVLERVDAAGADQGELDRLV 4860

Query: 1146 AHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAA 1205
                    D++ P  G+++RA+WF G     +P + L L AHHL VD VSW I+  DL +
Sbjct: 4861 RTHCAAARDRLAPQKGSVLRAVWFDGGPR--EPGH-LALVAHHLVVDGVSWRILTADLGS 4917

Query: 1206 AWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPD 1265
            AW++L  G  P + P  T  R W   +   A+ P+  ++  +W      P    GL   D
Sbjct: 4918 AWQALAEGREPHLDPVGTPLRIWARHLAELAADPRRAERCAHWEEQSPRPWETGGL---D 4974

Query: 1266 PTRDTWSTLQLTRAAIPVDVTERVLGAV--RRDQGVRELLLAATAMAVASWRRVRAQDPA 1323
            P  D  ST +     +P   T  VLG V      GV E+LL   A AV   RR R  + A
Sbjct: 4975 PALDDRSTEEALSLTLPAAATRAVLGPVPAALGVGVSEVLLGTFAAAV---RRRRPAEAA 5031

Query: 1324 AGVLVALEGHGR-ADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLV 1382
             GV V LEGHGR  D V   D + TVGWFT A PVR+ A        + + D   A   +
Sbjct: 5032 DGVTVDLEGHGREEDVVPGADLSRTVGWFTAAHPVRVPAA-------RPDEDRTGA---L 5081

Query: 1383 HSVVSHLEAIPNDGLDYGLLRYVDGVA--ELVDAVDPQIQFSYLGRLDLGGV---AD--- 1434
             ++ + L+  P+ GL YGLLRY++      L     P+  F+YLGR    G    AD   
Sbjct: 5082 RALAAILDRAPDAGLGYGLLRYLNPRTRQRLAALPAPRYGFNYLGRFGGSGEDRDADDRT 5141

Query: 1435 QPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDID 1494
              WS    P    L   P   LPL   + ++       EG +LI  W W+  +    D+ 
Sbjct: 5142 SNWS----PVAAGLAGQP-AQLPLAHEIEVTAVAVEGPEGPRLIATWSWAGRLHRERDVR 5196

Query: 1495 HLTGLWQRGIAALAA 1509
             L  LW R +  LA+
Sbjct: 5197 ELAELWFRELEELAS 5211



 Score =  441 bits (1134), Expect = e-121
 Identities = 446/1450 (30%), Positives = 634/1450 (43%), Gaps = 157/1450 (10%)

Query: 8    IEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLR 67
            +ED+L ++PLQEGL          +D+Y  Q    ++G +D + LR +A A+L RH +LR
Sbjct: 1572 LEDILPVAPLQEGLLFHSVYDRRALDVYVGQLAFRLEGEIDQDALRTAAAALLARHTSLR 1631

Query: 68   AAFWDRDVPKPVQIVPVHAALPW----------------SERVATPAEFDSIARSERRRP 111
              F  R+  + VQ V     LPW                +    +   ++ +A +ER   
Sbjct: 1632 TGFHQRESGQWVQAVARSVELPWQFHDLLDPHGAGGAAGAADAGSGRRWEELAAAERVER 1691

Query: 112  FDLSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXX 171
            FDL+R P +R ++     E + + + T HH +VDGWS+ +   ELLA+            
Sbjct: 1692 FDLTRPPLVRFLLARTAPE-RYQFVITTHHTIVDGWSIPILLRELLALYGGDPLPPAPGH 1750

Query: 172  XXXXXXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTA 231
                  +  WLA +D  AA   W   L     P ++A  A      P    L LP   +A
Sbjct: 1751 RL----HADWLAARDLVAAREAWTRALADTEGPTLLAPGAPRVGEVPRSVRLNLPEEVSA 1806

Query: 232  RLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINA 291
            RL   A   G TLN+ V   WA+VL++ T R DV FG  VSGRP +LPG E +VG+ +N 
Sbjct: 1807 RLLTRAREAGATLNSVVQAVWALVLAQETGRSDVTFGITVSGRPAELPGAENLVGMLVNK 1866

Query: 292  VPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPID 351
            VP+   +   E ++    +++R+   + +  ++ L+ + R  G   LFD+  VFEN P +
Sbjct: 1867 VPLRVRLRPAEPLMELARRLEREQLELLEHQHVPLTTLHRWSGLPELFDTTMVFENYPAE 1926

Query: 352  DAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGER 411
               R A  P  A        S  HYPLT+V  +R                   A  +GER
Sbjct: 1927 VTARQA--PFRAS--GTASYSRNHYPLTLVGAMRGTELTVRVDHRPDLFDEDFARSLGER 1982

Query: 412  MLTVLRQLPD---IGDGTPDDLDIRTAAELKAHGL-LAARSAPTFDTTVWEMFERQVQXX 467
            ++  L +  D   +  GT D L     A L   G   A   AP    T  ++FE Q    
Sbjct: 1983 VIAALTEAADHPFVPAGTLDLLGAEERARLLEWGTGPAPEDAP---RTYVDLFEEQAART 2039

Query: 468  XXXXXXXXXXGVRHTYAELHARACR----LAGELAEHGVGPETVVALVLPRSERSXXXXX 523
                      GV  TYAEL  +A      LAG     G G E  + ++ PR         
Sbjct: 2040 PDAPAVISSDGVL-TYAELDRQANGVARWLAGRAGSAG-GAEVHIGVLAPRRPEVLAVLL 2097

Query: 524  XXXXXXXXYLPVDVTLPSARVESIVRQASPALAIT-EADYSQLVGTAVPTLALDDPAAVE 582
                    Y+P+D   P+ R+ +++    PAL +   A  S     +  T+   DPAA  
Sbjct: 2098 GVLKSGAAYVPLDEQWPAERLRTVLEDCRPALVLAPTAARSDAARESGATVLPVDPAA-- 2155

Query: 583  SISRRSAAAPTVDRR-----PEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYX 637
             ++      PT   R     P  +AY ++TSGSTG PKGVV  ++A+ +Y    A R Y 
Sbjct: 2156 -LAAHGPQTPTDAERIRPLTPGAAAYALYTSGSTGRPKGVVIDHSALAAYVGG-ARRRYP 2213

Query: 638  XXXXXXXXXXXXXHAWSLSFDASWQPMV-GLLDGHEIHLFDAEE-MRDADRLVEGIAIGQ 695
                            SL+FD +   ++  L  G  + L + +E  RDA           
Sbjct: 2214 DAAGTSLAHT------SLAFDLTVTTLLTPLTAGGAVRLGELDETARDAG---------- 2257

Query: 696  IDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGL---WDQLRGLSQMAVYNCYGPT 752
              ++  TPS    LS      ++   L LGGEA+  G    W +L   +Q  V N YGPT
Sbjct: 2258 ATLVKATPSHLPLLSELPGALNDGGTLILGGEALTGGRLRPWRELHPDAQ--VVNAYGPT 2315

Query: 753  EMTVEXXXXXXKDYRKP----------TIGTANAGTFGYVFDSALRMVPDGVVGELYLSG 802
            E+TV        +YR P           IG   AG   +V    LR VP  V GELY+SG
Sbjct: 2316 ELTVN-----CTEYRLPKGEPVGEGPVPIGRPFAGVRVHVLGPGLRPVPAEVPGELYVSG 2370

Query: 803  AQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGY 861
              +ARGY+GRP +TA RFVA P   PG+RMYRTGDLVR  S G   YVGR+D QVK+RG+
Sbjct: 2371 VGVARGYLGRPALTAERFVACPFGEPGERMYRTGDLVRWRSDGQLEYVGRSDDQVKLRGF 2430

Query: 862  RVEVGEIEAALRGQPGVHDAAVSVLR--QQDRTSLVGFVVWQDNMHE-DLIKLRAGLTER 918
            RVE  E+  AL   P V  A V VLR  Q     LVG++V        D   +   +   
Sbjct: 2431 RVETAEVARALETCPSVGSAMV-VLREDQPGDQRLVGYLVPAAGSGALDKEAVSDAVRAV 2489

Query: 919  LPSYMVPARIVTL-PRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCEL 977
            LP YMVP+ +V L    P+  NGK+D  AL   A +A  + S G A       E +LC L
Sbjct: 2490 LPEYMVPSALVVLEDGPPLTVNGKVDRSALP--APEAEPARSAGRAPRG--PREEILCGL 2545

Query: 978  FEEQLNA-VPHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRM--VLTATTIRQLGAAI 1034
            F + L      +DDD F  G  S++AI ++ + R   L VD  +  +  A T+ +L A +
Sbjct: 2546 FADVLGVRAVGVDDDFFALGGHSLLAIVVISRIRAL-LDVDVAIDALFEAPTVARLAAHL 2604

Query: 1035 DAAVDSQDAPADADYGAVRP-------LPMV-----SWLYEY--GNYRRFTHTVLLRLPS 1080
            D             +GAVRP       LP+       WL     G    +T  + LRL  
Sbjct: 2605 DG--------PGRGHGAVRPAVPRPGRLPLSYAQLRLWLLHQIEGPSATYTIPLALRLTG 2656

Query: 1081 GIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDE 1140
             +D +++   L  ++  H++LR++  E   GP  +   P    AE  L  +  P   D  
Sbjct: 2657 PLDVAALRAALGDVVARHESLRTVFAEDEHGPHQIVLAPG--DAEPGLKAV--PTTEDRL 2712

Query: 1141 LASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIML 1200
             +   A AAR      D      V A  F   E      ++LLL  HH+A+D  S   ++
Sbjct: 2713 RSDLEAEAAR----PFDLGQAPPVHARLFVLDER----THVLLLAVHHIAMDGWSVRPLV 2764

Query: 1201 GDLAAAWRSLQAGTP---PKILPEFTSYRRWC--ELMWHRASAPQVQDQRDYWA----AL 1251
             DLA+A+ + + G     P +  ++  Y  W   EL         +  Q  YW      L
Sbjct: 2765 RDLASAYAARRRGASLDLPALPVQYADYTLWQHEELGSEDDPDSPLAAQLRYWRRTLDGL 2824

Query: 1252 VREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAV 1311
             +E  PA     P         + LT   +P ++  RV+   R  +    +++ A A+A 
Sbjct: 2825 PQESAPAADRPRPATPSYRGGRVALT---VPPELHGRVVELAREFRATPFMVVHA-ALAA 2880

Query: 1312 ASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQA 1371
               R     D   G  VA    GR D  L+    + VG+F N   +R          E  
Sbjct: 2881 LLTRLGAGTDVPIGSPVA----GRVDDALE----DLVGFFVNTLVLRTDTSGDPTFGELL 2932

Query: 1372 ERDPVAAQDL 1381
            ER  V A DL
Sbjct: 2933 ER--VRATDL 2940



 Score =  389 bits (998), Expect = e-105
 Identities = 429/1447 (29%), Positives = 615/1447 (42%), Gaps = 127/1447 (8%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            L LS  Q  L+ LHQ+ E     Y++   + + GP+D+  LR +   ++ RH +LR  F 
Sbjct: 2624 LPLSYAQLRLWLLHQI-EGPSATYTIPLALRLTGPLDVAALRAALGDVVARHESLRTVFA 2682

Query: 72   -DRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSVPGE 130
             D   P  + + P  A         T     S   +E  RPFDL + P +    L V  E
Sbjct: 2683 EDEHGPHQIVLAPGDAEPGLKAVPTTEDRLRSDLEAEAARPFDLGQAPPVHAR-LFVLDE 2741

Query: 131  TKRRMIFTAHHILVDGWSLAVFFTELL---AVXXXXXXXXXXXXXXXXXXYIVWL----- 182
                ++   HHI +DGWS+     +L    A                   Y +W      
Sbjct: 2742 RTHVLLLAVHHIAMDGWSVRPLVRDLASAYAARRRGASLDLPALPVQYADYTLWQHEELG 2801

Query: 183  AKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKP-------GKTELLLPAADTARLRQ 235
            ++ D  + LA  + Y R   + L       A + +P       G+  L +P     R+ +
Sbjct: 2802 SEDDPDSPLAAQLRYWRRTLDGLPQESAPAADRPRPATPSYRGGRVALTVPPELHGRVVE 2861

Query: 236  WAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVV 295
             A     T    V  A A +L+RL    DV  G+ V+GR D    +E +VG F+N + + 
Sbjct: 2862 LAREFRATPFMVVHAALAALLTRLGAGTDVPIGSPVAGRVDD--ALEDLVGFFVNTLVLR 2919

Query: 296  HYVSGTEAVVAQCTQVQRQ---SSAMRDVSYLSLSEI---QREHGRGPLFDSLFVFENA- 348
               SG         +V+     + A +D+ +  L E+   +R   R PLF  L  F N  
Sbjct: 2920 TDTSGDPTFGELLERVRATDLGAYAHQDLPFERLVEVLNPERSLARHPLFQILLAFNNGA 2979

Query: 349  -----PIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYL 403
                 P D A      P+  +    + +    +     +                     
Sbjct: 2980 APDEGPADRASDVLVRPETVEIAAAKFDLSLSFNEDRAADGTAAGMRGVLEYSADLYDES 3039

Query: 404  PAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARS---APTFDTTVWEMF 460
             A  + ER L +L     + +       I   +E + H +L  R+       D++    F
Sbjct: 3040 TARRMAERYLRLLEAA--VAEPRTPLSRIPVLSEAELHDVLVRRNDTGRTRPDSSPLRRF 3097

Query: 461  ERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXX 520
            E Q                R  YAEL ARA RLA  L+    G    VA+ LPR      
Sbjct: 3098 EAQAATTPRATALVVGEE-RLDYAELDARAERLATLLSRSTAGRGGPVAVALPRGVMLPV 3156

Query: 521  XXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQ-LVGTAVPTLALDDPA 579
                       YLP+D   P +R+  ++  ++P   IT  D ++ L     P L LDDPA
Sbjct: 3157 ALLAVWKAGLHYLPLDPDHPRSRLADVLADSAPGCVITTTDLARRLPPVPAPLLVLDDPA 3216

Query: 580  AVESISRRSAAAPTVDRRP------EQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAE 633
                ++  +A A   D R       E+ AY I+TSGSTG PKGV+ T +AV ++ AD  E
Sbjct: 3217 TAARLAATTATALAEDPREQNGEWGEELAYTIYTSGSTGRPKGVMVTRSAVANFLADMNE 3276

Query: 634  RVYXXXXXXXXXXXXXXHAWSLSFD-ASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIA 692
            R+                  ++SFD A  + +  LL G  + L DA   RD   +    A
Sbjct: 3277 RLELGPGDRLLAVT------TVSFDIAVLELLAPLLTGGTVVLADATTQRDPAAVRSLCA 3330

Query: 693  IGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLR--GLSQMAVY--NC 748
               + +I  TPS +  ++  G LD     + +GGEA+   L   L   G + +  Y  N 
Sbjct: 3331 REGVTVIQATPSWWHAMAVDGGLDLTALRVLVGGEALPPALARTLLEPGRAPLGDYLLNL 3390

Query: 749  YGPTEMTV-------EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLS 801
            YGPTE TV                   PT GT  A T  YV D+ALR VPDGV GELYL+
Sbjct: 3391 YGPTETTVWSTVARITADSLEAHGGAVPT-GTPIARTAAYVLDAALRPVPDGVPGELYLA 3449

Query: 802  GAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRG 860
            GA LARGY+GRPGMTA RFVA P   PG+RMYRTGDL R  + G   ++GR D QVK+RG
Sbjct: 3450 GAGLARGYLGRPGMTAERFVACPFGEPGERMYRTGDLARWRADGNLEHLGRTDDQVKVRG 3509

Query: 861  YRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTS-LVGFVVWQDNMHE-DLIKLRAGLTER 918
            +R+E+GE+E AL    GV  AA +V      ++ LVG++V        D   +   +   
Sbjct: 3510 FRIELGEVERALTQAHGVGRAAAAVHPDAAGSARLVGYLVPAGGSGALDEKAVADAVRAV 3569

Query: 919  LPSYMVPARIVTLP-RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCEL 977
            LP+YMVP+ +V L   LP+ ANGKLD  AL   A +A T    G A       E +LC L
Sbjct: 3570 LPAYMVPSALVVLDGGLPLTANGKLDRAALP--APEATTGRGPGRAPRG--PREEILCGL 3625

Query: 978  FEEQLNA-VPHIDDDLFLFGMDSIVAISLVHKAR-RQGLRVDPRMVLTATTIRQLGAAID 1035
            F + L      +DDD F  G  S++A  L+ + R   G+ +  R V    T+  L AA+ 
Sbjct: 3626 FADVLGVPAVGVDDDFFALGGHSLLATRLIARVRGTLGVELGVREVFETPTVAGLAAALS 3685

Query: 1036 AAVDSQDAPADADYGAVRPLPMVS-----WLYEYGNYRRFTHTV--LLRLPSGIDRSSIE 1088
            AA ++      AD    R LP+       W          T+ V   LRL   +D +++ 
Sbjct: 3686 AAGEAGPRLRPADPRPER-LPLSHAQRRLWFVRQLEGPSATYNVPWALRLTGPLDVAALR 3744

Query: 1089 LMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDE-----LAS 1143
              L  ++  H++LR++  E   GP  V      V + D    ++ P  +D++     L  
Sbjct: 3745 AALGDVVARHESLRTVFAEDEHGPHQV------VLSADGPAPLSGPVRTDEDALPRLLRE 3798

Query: 1144 AVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDL 1203
            A  HA R+        A   +RA  F      A   + LLL  HH+A D  S   ++ DL
Sbjct: 3799 AADHAFRL-------DAEPPLRAHLFA----TAPEDHTLLLVMHHIATDAWSQRPLIADL 3847

Query: 1204 AAAWRSLQAGTPPKILP---EFTSYRRW--CELMWHRASAPQVQDQRDYWA-ALVREPDP 1257
            AAA+ +  AG  P + P    +  Y  W    L   R     +  Q  YW  AL   P+ 
Sbjct: 3848 AAAYAARHAGRVPTLPPLPVAYADYALWQQARLGDEREKDSALSAQLAYWRDALAGSPEE 3907

Query: 1258 -ALGLRYPDPT--RDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASW 1314
             AL    P P        ++ LT   +P ++  RV+   R  +    +++ A A+A    
Sbjct: 3908 LALPADRPRPAVPSHRGDSVPLT---VPPELHGRVVELAREFRATPFMVVHA-ALAALLT 3963

Query: 1315 RRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERD 1374
            R     D   G  VA    GR D  L+    + VG+F N   +R          E  ER 
Sbjct: 3964 RLGAGTDVPIGSPVA----GRVDDALE----DLVGFFVNTLVLRTDTSGDPTFGELLER- 4014

Query: 1375 PVAAQDL 1381
             V A DL
Sbjct: 4015 -VRATDL 4020


>tr|C0ZRD6|C0ZRD6_RHOE4 Tax_Id=234621 SubName: Full=Putative
            non-ribosomal peptide synthetase;[Rhodococcus
            erythropolis]
          Length = 5564

 Score =  620 bits (1600), Expect = e-175
 Identities = 504/1533 (32%), Positives = 714/1533 (46%), Gaps = 97/1533 (6%)

Query: 6    PQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPN 65
            P+ E++L L+PLQEG++     A+ G D Y +Q VV++ G VD   LRR+ Q+++DRH  
Sbjct: 1527 PKAEEILPLTPLQEGIYFHSAFADPGADQYVVQQVVELTGAVDSAALRRALQSVVDRHEA 1586

Query: 66   LRAAFWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVL 125
            LR  F      + VQ+V     +  +      A+ D +  ++R R FDL++ P +R  +L
Sbjct: 1587 LRTGFSVLGDGRVVQVVHPSVVVEMAVVTDAGADVDELLSADRARGFDLAQPPLVRYTLL 1646

Query: 126  SVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAKQ 185
                E K  ++ + HH + DGWS+ V   EL+A                   Y+ WLA  
Sbjct: 1647 RASSE-KNLLLQSIHHAVADGWSVPVMLRELMASYSVGDSGVVLPSPAPYRSYLEWLAGH 1705

Query: 186  DRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGRHGLTLN 245
            D  A+ A W   L     P +     +AG S    T + L  +DT  L      +GLTL+
Sbjct: 1706 DHEASAAVWRKALNSPG-PAVELPAPSAGSSGIHATRVGLSDSDTRALSTTGRSYGLTLS 1764

Query: 246  TAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEAVV 305
            T V  AW +VL R+T R DV+FG+ VSGR   LPG+E+MVGLFIN VP        E   
Sbjct: 1765 TLVHGAWGLVLGRMTGRTDVLFGSTVSGRGGDLPGIESMVGLFINTVPARLRFDPAETAA 1824

Query: 306  AQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDGAQF 365
               ++ QR+ S + D  YL L E++R  G    F+SL VFEN P+ D      T +  + 
Sbjct: 1825 QALSRWQREQSELLDHQYLGLPELRRTGGLEQNFESLVVFENYPLGDTAIADPT-NSVRL 1883

Query: 366  LPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQLP-DIGD 424
              +  +    YPLT++  +                    AA + E +  VL +L  D+  
Sbjct: 1884 TGIRFDERPAYPLTLIV-VPGDQLALELKYDAAQVDGDAAASLAEALAVVLTELSRDL-- 1940

Query: 425  GTPDDLDIRTA-AELKAHGLLAARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTY 483
               D +  R A A  +   +  A   P   TT+ E+ + Q                  TY
Sbjct: 1941 ---DQVIARIALAPAQPGSIGTALDRPR--TTLTELLQDQAGRTPEATAVIFREESL-TY 1994

Query: 484  AELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSAR 543
            AELH+RA R A  L E GVG E++VA+ LPRS                Y+P+D   P+ R
Sbjct: 1995 AELHSRADRFAHLLHERGVGRESLVAVALPRSVDLMVAILGIGKAGGAYVPLDTGYPAER 2054

Query: 544  VESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSAY 603
            +  ++  A P   +   D S L   +VP + + + A         A   +V   P  +AY
Sbjct: 2055 LTYMLDDADPVCVVVSED-SSLDSGSVPRVTVSESAQFP------AEPLSVPGSPADAAY 2107

Query: 604  VIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDAS--- 660
            +I+TSGSTG PKGVV TN  V++        ++                   SFD S   
Sbjct: 2108 MIYTSGSTGRPKGVVVTNEGVVNRL------LWAQQIRPLDFSDRMLQKTPSSFDVSVPE 2161

Query: 661  --WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAA--GLLD 716
              W  +VG      + + + +  +D   L + I    +  +   PSM     A     L 
Sbjct: 2162 FFWPFLVGAT----LVMAEPDGHKDPGYLADVIVEHSVTRVHFVPSMLEVFLAEPKAALC 2217

Query: 717  HNLSVLALGGEAINTGLWDQLRG-LSQMAVYNCYGPTEMTVEXXXXXX-----KDYRKPT 770
             +L ++   GEA+   +  ++   L  + V N YGPTE  V+            D     
Sbjct: 2218 TSLEIVNCSGEALPVHVARKVAEILPNVLVDNLYGPTEAAVDVSWQPSVQETPADAVSVP 2277

Query: 771  IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRPG-Q 829
            IG   A T  +V D  L+ VP G  GELYL+G QLARGY GR G+T+ RFVA+P   G  
Sbjct: 2278 IGEPAANTGLFVLDPYLQNVPAGATGELYLAGPQLARGYHGRGGLTSERFVANPYSDGGS 2337

Query: 830  RMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQ- 888
            RMYRTGD+VR    G   Y+GR D QVK+RG+R+E+GEIEA L   PGV  +AV V    
Sbjct: 2338 RMYRTGDIVRWNGDGVLEYLGRVDEQVKVRGFRIELGEIEAQLALCPGVSASAVIVRTDG 2397

Query: 889  -QDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHAL 947
              DR  +V ++V       D   +R  L   LP +MVP+  V L  LP++ +GKLD  AL
Sbjct: 2398 PSDRAQVVAYLVGD----ADDAAVRGQLLSVLPEFMVPSAFVRLESLPLSPSGKLDRKAL 2453

Query: 948  DRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPHID--DDLFLFGMDSIVAISL 1005
               A D    V   T V  S+    +L   F   L  +P +   DD F  G DSI+AI L
Sbjct: 2454 P--APDFAAQVGETTGV-VSSGVADLLARHFATVL-GLPRVGARDDFFTLGGDSILAIRL 2509

Query: 1006 VHKARRQGLRVDPRMVLTATTIRQLGAAI-DAAVDSQDAPADADYGAVRPLPMVSWLYEY 1064
            V+ ARR  + + PR +    T   + AA+ D A       AD   G + PLP+V  L E+
Sbjct: 2510 VNLARRDSVVLTPRQIFELRTPAAIAAAVGDVATSVATVTADIGVGELVPLPVVHRLSEW 2569

Query: 1065 -GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGP-RLVTREPAAV 1122
             G   RF   VL+  P+     SI   LQ +LD HD LR  L     G       EP ++
Sbjct: 2570 TGGTDRFNQAVLIHSPA-TSLDSITGALQAVLDHHDGLRQTLIRHDRGMWSARIEEPGSI 2628

Query: 1123 RAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANIL 1182
            RA +++ R+      D EL + +   +   T ++DPSAG MV  +WF   +  A+    L
Sbjct: 2629 RAANLVVRVDARGLDDAELRTLITERSEWATSRLDPSAGRMVSVVWF---DCGAENLGRL 2685

Query: 1183 LLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQ 1242
             + AHHL VD VSW  +L DLA AW +++AG P  +    TS R +   +   A +    
Sbjct: 2686 AIVAHHLVVDGVSWGTLLEDLAMAWVAVEAGEPAALDAVGTSLRTFSRTVAEHAYSAHRF 2745

Query: 1243 DQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVD--VTERVLGAVRRDQGVR 1300
             + D+W  +      A G      T         +R  + VD  ++E  LG V    G  
Sbjct: 2746 AELDHWLTVT-----APGAELIPGTASYAVVSGGSRRTVTVDGAISEAALGTVPAMLGAE 2800

Query: 1301 --ELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
              ++LLAA AM+V  WRR   +     +LV LE HGR + V  TD + TVGWFT   P+R
Sbjct: 2801 GTDVLLAALAMSVDRWRRSTGRSERE-LLVDLERHGREELVPGTDLSRTVGWFTTIAPMR 2859

Query: 1359 LGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDG--VAELVDAVD 1416
            L  G           DPV   D +  V   L A P+ G+ YG+LRYV+    + L    +
Sbjct: 2860 LLGGT----------DPV---DTLREVKESLRAAPDGGIGYGMLRYVNARTASRLAGRSE 2906

Query: 1417 PQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQ 1476
             QI F+YLGR    G     WSL      +A+  DP+ D+   + L     V V +  ++
Sbjct: 2907 SQILFNYLGRTTTAG--STAWSLAAES--EAMSTDPDADMGGPYRL----IVNVVSVESE 2958

Query: 1477 LIGNWRWSDAVFERSDIDHLTGLWQRGIAALAA 1509
            L  ++ W+       D   L+  W   +  LAA
Sbjct: 2959 LRADFAWASEDLSMEDAQSLSDGWVSALGDLAA 2991



 Score =  536 bits (1380), Expect = e-149
 Identities = 447/1416 (31%), Positives = 660/1416 (46%), Gaps = 110/1416 (7%)

Query: 3    AAAPQIEDVLALSPLQEGLF-----ALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQ 57
            A+   +  +L LSPLQEGL+     A    +  G D+Y+ QF +D    +D++ L  +A+
Sbjct: 3023 ASPAGVSSILPLSPLQEGLYFQAGYAGSSDSRSGGDIYTAQFSMDFGHTLDVDRLAAAAR 3082

Query: 58   AMLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWS-------ERVATPAEFDSIARSERRR 110
             +  R+P LRA F    + +P Q       +P +       +  A     +++A  +R  
Sbjct: 3083 TLQRRNPTLRAGFVSEGLNEPAQFFSAGLDVPVAVHDLRELDDSAARERAEAVAAQDRVT 3142

Query: 111  PFDLSRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXX 170
            PFDL+  P  R+ VL +PG   R ++     +L DGWS  +  ++LLA+           
Sbjct: 3143 PFDLTAPPLWRMSVLHLPGGHDR-LVINRQFLLWDGWSNGLVVSQLLALYDTGGDDSAFG 3201

Query: 171  XXXXXXX-YIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSK--PGKTELLLPA 227
                    Y+ WLA +D +AA AGW   L G+ EP +VA E T G     P + + +L  
Sbjct: 3202 EPEGSFEAYLAWLADRDGAAADAGWRGALAGLEEPTLVA-EPTPGVEPQLPDRRDAVLSE 3260

Query: 228  ADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGL 287
            + +  LR+ A   G+T NT +  A A+VL+  T R+DVVFG+ V+GRP ++PG++T+VG+
Sbjct: 3261 SLSRALRERAAASGVTFNTVLNAALALVLASATGRQDVVFGSTVAGRPPEVPGIDTVVGM 3320

Query: 288  FINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFEN 347
            F+N VPV   +   E+V     + Q    +     YL L+ IQR      LFD L V +N
Sbjct: 3321 FLNTVPVRLQLDPNESVEELLRRTQADRLSQMPFDYLGLASIQRVSEHRQLFDVLMVLQN 3380

Query: 348  APID---DAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLP 404
               +   DA+  A    G+  +       THYPLTVV                   P+L 
Sbjct: 3381 FVDEKQVDALNAAHDVSGSDSI-----DHTHYPLTVV-----VTPGATVNVKFEFHPHLV 3430

Query: 405  AAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAA-RSAPTFDTTVWEMFERQ 463
             A   E +L     L  +   + D      A+ + A G L   R  P  + T+ ++FE +
Sbjct: 3431 TARRAEDLLGHFVDL--LQSWSHDMTGSVVASPVPAVGRLTQIRDLP--ERTIADLFE-E 3485

Query: 464  VQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXX 523
            V               R TYA+L     R+A  L  +G GPE +VAL LPRS        
Sbjct: 3486 VASTQPIDTALVFGKRRMTYADLDGEINRMARLLINYGAGPEKIVALGLPRSVDMVVALF 3545

Query: 524  XXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQL-----VGTA-VPTLALDD 577
                    YLP+++  P+ R+  ++  A P + +T    +       V TA + T+ LD+
Sbjct: 3546 AVLRTGAAYLPLELDHPAERLAVMIDDADPVVLLTTVAAAPKFEGADVRTADIRTIVLDE 3605

Query: 578  P----------AAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSY 627
            P          A   S +   A AP    R +  AYVI+TSGSTG+PKGVV     + + 
Sbjct: 3606 PDTAARRLTISARALSAAELGAFAPGAPHRLDHPAYVIYTSGSTGKPKGVVTGYRGLTNM 3665

Query: 628  FADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRL 687
              +H E ++              H  S +FD SW+ ++ L++GHE+H+ D +  RDA+ L
Sbjct: 3666 QFNHREAIFEPVIAATSRRLRIAHTVSFAFDMSWEELLWLVEGHEVHICDEDLRRDAEAL 3725

Query: 688  VEGIAIGQIDMIDTTPSMFVQLSAAGLLD-----HNLSVLALGGEAINTGLWDQLRGLSQ 742
            V      +ID+++ TP+    L  +GLLD     H   ++ LGGEA+   +W++LR    
Sbjct: 3726 VAYCDAQEIDVVNVTPTYATHLIDSGLLDDGVGQHRPPLVLLGGEAVPDSVWNRLRDTEG 3785

Query: 743  MAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSG 802
               YN YGPTE T+        D   PT+G     T  ++ D  LR VPDGV GELY++G
Sbjct: 3786 TVGYNLYGPTEYTINTLGGGTTDSDTPTVGKPIWNTAAHILDGWLRPVPDGVAGELYIAG 3845

Query: 803  AQLARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYR 862
            A LARGY+GR  +T+ RFVADP   G+RMYRTGDLVRR + G   ++GR D QVKIRG+R
Sbjct: 3846 AGLARGYLGRFALTSERFVADPAGTGERMYRTGDLVRRRADGNLDFLGRTDDQVKIRGHR 3905

Query: 863  VEVGEIEAALRGQPGVHDAAVSV-LRQQDRTSLVGFVV-WQDNMHEDLIKLRAGLTERLP 920
            +E  EI + L     V  AAV V +       LVG+V   Q     D    RA    RLP
Sbjct: 3906 IEPSEIVSVLESDEHVRQAAVVVDVGAGGVKRLVGYVTPAQLGAAHD---YRAQARVRLP 3962

Query: 921  SYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEE 980
             YMVPA ++ +  LP+  NGKLD   L     D++     G +++    TE VLCELF +
Sbjct: 3963 DYMVPAVVIEVESLPMTVNGKLDVKVLP--TADSVLGERSGESIAPRNHTEEVLCELFSD 4020

Query: 981  QLNAVP-HIDDDLFLFGMDSIVAISLVHKAR-RQGLRVDPRMVLTATTIRQLGAAIDAAV 1038
             L+     +DD+ F  G  S++A  L+ +AR      +  R +  A T+ +L   I   V
Sbjct: 4021 VLDVDDIGVDDNFFDLGGHSLLATKLISRARIAIPNSLTMRDLFEAPTVAELAERI---V 4077

Query: 1039 DSQDAPADADYGAVRP--LPMVS-----WLYEY--GNYRRFTHTVLLRLPSGIDRSSIEL 1089
              Q +         RP  LP+ +     WL      N   +   ++LRL S +D      
Sbjct: 4078 VEQGSTRPMLVAKPRPDHLPLSAAQQRLWLIGQMEENSAAYNFPIVLRLDSALDADVFAA 4137

Query: 1090 MLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAA 1149
             L  ++  H++LR++       P  +  E A V  E V +R     G   E+A AV    
Sbjct: 4138 ALGDVVGRHESLRTVFRLVDGTPEQIILESAKVPVETVHSR---ESGVAGEVAVAVGR-- 4192

Query: 1150 RVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRS 1209
                   D S    +RA        R D A I+++  HH+  D  S    L DL +A+ S
Sbjct: 4193 -----PFDLSNEIPIRARLI-----RVDGAVIVVIVLHHITTDEWSDRPFLRDLMSAYSS 4242

Query: 1210 LQAGTPPKILP---EFTSYRRWCELMWHRASAPQ--VQDQRDYWA-ALVREPDP-ALGLR 1262
               G  P   P   ++  Y  W   +   A  P   +  Q D+WA +L   P+   L   
Sbjct: 4243 RIQGEEPAFEPLPVQYADYTLWQRELLGSADDPSSVLSTQLDFWAKSLDGAPEELLLPAD 4302

Query: 1263 YPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDP 1322
               P R ++S   +    + VD T  +    R  Q    ++L A + A+ +      +D 
Sbjct: 4303 RSRPARPSFSGGAVV-TRLGVDTTAALRDLARESQSSMFMVLHAASAALLT-ALGAGEDL 4360

Query: 1323 AAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVR 1358
              G  VA    GR++  LD    + VG+F N   +R
Sbjct: 4361 PLGAPVA----GRSEQGLD----DLVGFFVNTIVLR 4388



 Score =  442 bits (1137), Expect = e-121
 Identities = 348/1055 (32%), Positives = 482/1055 (45%), Gaps = 69/1055 (6%)

Query: 479  VRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVT 538
            VR TY EL +R  +LA  L   GV PETVVA+ LPRS                ++P+D +
Sbjct: 490  VRLTYGELESRVSQLAAHLISRGVAPETVVAIGLPRSAEMVVGLLAVMCAGGAFVPLDPS 549

Query: 539  LPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDD-PAAVESISRRSAAAPTVDRR 597
             P+ R ES++  A   L +T       V   +   A +D P+ +  I         +   
Sbjct: 550  WPAERRESVLADAGATLVLTSDGVDDSVLVDLSAWAYEDGPSGLSEIMTSG-----IRIH 604

Query: 598  PEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSF 657
              Q AYVIFTSGSTG PKG +  + A+ +      ER+                   LSF
Sbjct: 605  GAQLAYVIFTSGSTGRPKGAMIRHEAICARLLWQRERILGFGSGDASLFKAP-----LSF 659

Query: 658  DASWQP-MVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMF-VQLSAAGLL 715
            D S    ++ L+ G  + +   E  RD   L++ IA   +  +    SM  + L  A   
Sbjct: 660  DISINEILLPLVSGGRLVIAKPEGERDPQYLLDLIAGESVTFVYLVSSMLDILLDLANGT 719

Query: 716  DH--NLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRK---PT 770
            D   +L  +  GGE +   L+D+ R      +Y+ YGP E T+       ++  +    +
Sbjct: 720  DQLDSLKHVWCGGEVLTPELFDRFRAQLSTTLYHGYGPAEATIGVSHVIYREDAERIATS 779

Query: 771  IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL----R 826
            IG  N  T  YV D  L+ VP G  GELY +G  L RGYVG   +TA+RF+ADP      
Sbjct: 780  IGRPNPNTRLYVLDGDLQPVPVGTGGELYAAGFLLGRGYVGASALTASRFLADPFVSGDL 839

Query: 827  PGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVL 886
             G RMYRTGDL R  + G   ++GR D QVKIRG R+E+ ++EAA+   PGV   AV V 
Sbjct: 840  AGSRMYRTGDLARWTADGTLDFLGRTDNQVKIRGMRLELEDVEAAVISHPGVRHVAVLVR 899

Query: 887  RQQDRTSLVGFVVWQ---DNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLD 943
            +       +   V      N+  D   +R     +LP YMVP  +  L   P+ ANGKLD
Sbjct: 900  QAPTGAKYLAAYVSAASGTNLAVDSQDIREWAASKLPDYMVPTTVTVLDEFPLTANGKLD 959

Query: 944  GHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIVA 1002
              AL    E  L  +S    V+A  + E+  C L    +      + DD F  G DSIVA
Sbjct: 960  RRALP---EPDLAELSAH--VAARNEVEQQFCNLIASAVGLESVGVTDDFFALGGDSIVA 1014

Query: 1003 ISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVSW-L 1061
            ISLV  AR  GL + PR V    T   +  A           AD   G V   P+ +  L
Sbjct: 1015 ISLVTAARAAGLSISPREVFQLRTAEAMARAQSGRTAEIVDHADEPIGHVATTPIAARAL 1074

Query: 1062 YEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAA 1121
                  R F    L++ PS +    +E  L  L+  HD LR+ LT   EG  LV   PA 
Sbjct: 1075 GTPDAARTFHQRALIQTPSALTSEHVEAALDALVARHDALRAKLTS--EGTLLV---PAT 1129

Query: 1122 VRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANI 1181
                 V     LP   ++     VA   R V  +++P+ G MV A+ F  +     P   
Sbjct: 1130 NELAVVFETRALPVPLEECGPLIVAETERAVR-RLNPADGTMVSAVLFTTS---TGPGR- 1184

Query: 1182 LLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQV 1241
            LLL  HH  VD VSW I+L DLA A  +   G  P + P  TS RR+ EL+       ++
Sbjct: 1185 LLLVIHHAVVDGVSWRIILEDLARAGIAAIQGDEPSLAPVGTSVRRYAELVSEAVGTGRL 1244

Query: 1242 QDQRDYWAALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRDQG--V 1299
              + ++W ++       LG R  DP  D   T       +P +  +R+LG+V R  G  V
Sbjct: 1245 DSEIEFWDSVTSARQSPLGRRALDPAVDLARTAAARSITLPPEFADRLLGSVPRAFGADV 1304

Query: 1300 RELLLAATAMAVASWRRVRAQDPAAGVLVALEGHG------RADAVLDTDTTNTVGWFTN 1353
             E+L+ A A+A++ W        AA V + LEGHG      R D     D T TVGWFT 
Sbjct: 1305 SEVLITALAVALSKW------SGAASVTIDLEGHGRDEDIVRGDGAAHVDLTRTVGWFTT 1358

Query: 1354 AFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVD 1413
             FPV L    AA D+E +    V    ++ SV   L  +PN G  YG LRY+    +L  
Sbjct: 1359 VFPVALEIDTAATDLEASGELAV----VLKSVKEQLRRVPNAGFGYGALRYLGSSDQLRS 1414

Query: 1414 AVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAE 1473
               P++  +YLGR     VA+  W      +  ++    +P +PL  AL++ V     A 
Sbjct: 1415 VAAPEVVLNYLGRT---AVAEGDW------FPVSMDGAADPSMPLGHALSVDVVAEEAAG 1465

Query: 1474 GTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALA 1508
            G +L     W+  +F RSDID    LW   + A++
Sbjct: 1466 GPRLRATLTWASNIFLRSDIDRFARLWLDSLKAVS 1500



 Score =  302 bits (774), Expect = 2e-79
 Identities = 393/1512 (25%), Positives = 613/1512 (40%), Gaps = 155/1512 (10%)

Query: 10   DVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAA 69
            D L LS  Q+ L+ + Q+ E+    Y+   V+ +D  +D ++   +   ++ RH +LR  
Sbjct: 4094 DHLPLSAAQQRLWLIGQMEENSA-AYNFPIVLRLDSALDADVFAAALGDVVGRHESLRTV 4152

Query: 70   FWDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSVPG 129
            F   D   P QI+   A +P     +  +           RPFDLS    +R  ++ V G
Sbjct: 4153 FRLVD-GTPEQIILESAKVPVETVHSRESGVAGEVAVAVGRPFDLSNEIPIRARLIRVDG 4211

Query: 130  ETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVWLAKQ---- 185
                 ++   HHI  D WS   F  +L++                   Y  +   Q    
Sbjct: 4212 AVI--VVIVLHHITTDEWSDRPFLRDLMSAYSSRIQGEEPAFEPLPVQYADYTLWQRELL 4269

Query: 186  ----DRSAALAGWMDY----LRGVSEPLMVAYEATAGQSKP-------GKTELLLPAADT 230
                D S+ L+  +D+    L G  E L++     A +S+P       G     L    T
Sbjct: 4270 GSADDPSSVLSTQLDFWAKSLDGAPEELLLP----ADRSRPARPSFSGGAVVTRLGVDTT 4325

Query: 231  ARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFIN 290
            A LR  A     ++   +  A A +L+ L    D+  G  V+GR +Q  G++ +VG F+N
Sbjct: 4326 AALRDLARESQSSMFMVLHAASAALLTALGAGEDLPLGAPVAGRSEQ--GLDDLVGFFVN 4383

Query: 291  AVPVVHYVSGTEA---VVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSLFV 344
             + +    SG      +V +  +   ++ A  DV + ++ E     R   R PLF  +  
Sbjct: 4384 TIVLRTDTSGNPTFRELVDRIREGDLEAFANADVPFETVVERLNPSRTLARNPLFQVMVG 4443

Query: 345  FENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYL- 403
            + +       R     D     P E+E  T     V +                    L 
Sbjct: 4444 YHS-------REEMGGD-----PFELEEYTAKFDLVFNFTEYLGDEGCIDVRLEYGSDLF 4491

Query: 404  ---PAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDT---TVW 457
                A  I  R+ +V+  + +  D    D+DI    EL+   ++ + +    D    T +
Sbjct: 4492 DRETAQRISNRLESVIAAVVESADIEIGDIDIFLPGELEQ--VVTSFNDTAVDVPEETFY 4549

Query: 458  EMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSER 517
            + F R V             G + TY EL  +  R+AG L   GV  E VV L +PRS  
Sbjct: 4550 DAFARGVAATPEAIAVRDEAG-QATYRELSEQCDRIAGVLYRRGVSVEDVVGLAVPRSVE 4608

Query: 518  SXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVG--TAVPTLAL 575
                          YLP+D++ PS R+  ++  +  ++ ++ ++ S  +     V  + L
Sbjct: 4609 MVASVLAVLKLGAAYLPLDLSHPSERIAYMLTDSRTSVLLSTSEESSRIEDVAGVERILL 4668

Query: 576  DDPAAVESISRRSAAAPTVDRRP---EQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHA 632
            DDP  +  +    AA     R P     +AYVI+TSGSTG+PKG V ++  + S  A   
Sbjct: 4669 DDPLILAELEE--AAIVETPRPPVGVNHAAYVIYTSGSTGKPKGAVLSHDGIPSLVATAE 4726

Query: 633  ERVYXXXXXXXXXXXXXXHAWSLSFD-ASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGI 691
             R+                  S+ FD A ++  + L     + +           L + +
Sbjct: 4727 VRMRLVPGSVVMQFA------SVGFDVAVFELAMALCTSSTLVIVPQSARVAGPALTDFM 4780

Query: 692  AIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGP 751
               ++      PS+   L A   +    +VL +G E +   L    R   ++ +   YG 
Sbjct: 4781 TSNRVTHAIIPPSLLAALPAGCEVPQGCTVL-VGTETVPPELIG--RWAERLNLLAAYGL 4837

Query: 752  TEMTVEXXXXXXKDYRKPT--IGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGY 809
            TE TV       +        IG  +     YV D  LR VP GV GELY++G  LARGY
Sbjct: 4838 TEATVNNTLWQAEPGWNGAVPIGVPDPNEQAYVLDDQLRPVPPGVSGELYIAGRGLARGY 4897

Query: 810  VGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIE 869
            +GR  +TA RF+ADP   G RMYRTGD  R  S G   ++GR D QVKIRG+R+E+GEI 
Sbjct: 4898 LGRFDLTAQRFIADPFTAGDRMYRTGDRARWRSDGNIDFLGRVDDQVKIRGFRIELGEII 4957

Query: 870  AALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIV 929
             AL   P V  A V   RQ + T LVG+V  +     D   +R      LP YMVP  +V
Sbjct: 4958 GALSAHPSVKQATVVADRQGEITRLVGYVSPEPGAVVDTTAVRNLAAMSLPDYMVPTMVV 5017

Query: 930  TLP-RLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEE--QLNAVP 986
             L   LP+  NGKLD  AL   A D  + ++G  A  ++   E  +   F E  QL +V 
Sbjct: 5018 ALDGPLPLTPNGKLDRKALP--APD-WSELAGDVAPRSA--VESTVAAAFAEILQLPSV- 5071

Query: 987  HIDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPA 1045
             + D  F  G  S+ ++ LV + R   G+ V  R V  A ++ +L A +  +   +   A
Sbjct: 5072 GVHDSFFELGGHSMASMKLVGRIREAFGVDVSIRDVFDAPSVAELAAVVARSEGGRPVLA 5131

Query: 1046 DADYGAVRPLPM-------VSW--LYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLD 1096
             A   A RP  M         W      G + + +H + L L S ID   +   L  +  
Sbjct: 5132 PA---ARRPETMGLSAPQRRQWELFRAAGEHPQASHALALTLNSKIDPEILGHALDDVTS 5188

Query: 1097 GHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQI 1156
             H+ LR+   E          +   V  E V   + + +    ++   V   A++  D  
Sbjct: 5189 RHEPLRTTFVEV---------DGIVVARESVRPTVEVVDVGAGDVGRVVFELAQLPMDLR 5239

Query: 1157 DPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPP 1216
            + S    +R     G     D +  LLL  H++AVD  S   +LGDL +A+ +   G  P
Sbjct: 5240 EQSP---LRVHLVLG----EDGSRTLLLVMHYIAVDEWSVVPLLGDLVSAYAARLQGDQP 5292

Query: 1217 ---KILPEFTSYRRWC-ELMWHRASA-PQVQDQRDYWAALVREPDPALGLRYPDPTRDTW 1271
               ++   +  Y  W  EL+        +   Q  YW   +     ++ L  P P  D+ 
Sbjct: 5293 IWDELALTYADYTVWSDELLGDPLDVDSRASKQLAYWQDALDGIPTSVNL--PLPEDDSE 5350

Query: 1272 STLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALE 1331
                +    I  D+  R+  A+    G    ++   A+A    +     D   G LVA  
Sbjct: 5351 PRGDVVSVDIDADLHARI-DALAARTGTSMFMVLQAALAAVLTKAGAGTDLPIGSLVA-- 5407

Query: 1332 GHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEA 1391
              GR+D  L+      +G F N   +R     +          P  A+ L      +LEA
Sbjct: 5408 --GRSDPRLEP----MIGSFFNVVLLRTDTSGS----------PTFAELLGRVREGNLEA 5451

Query: 1392 IPNDGLDYGLLRYVDGVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLTGPYLDALPID 1451
            + N  + Y    YV+       ++ PQ+   +  + DL G+ D         +   +PI 
Sbjct: 5452 LSNQDVSY---VYVEQALGNPASMRPQVMVIHHQQADLDGLGD---------FGSLVPIP 5499

Query: 1452 ---PEPDLPLRF 1460
               P+ DL L F
Sbjct: 5500 VGVPDADLTLSF 5511



 Score = 63.2 bits (152), Expect = 3e-07
 Identities = 81/345 (23%), Positives = 137/345 (39%), Gaps = 26/345 (7%)

Query: 1    VTAAAPQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAML 60
            V A A +  + + LS  Q   + L + A +     S    + ++  +D E+L  +   + 
Sbjct: 5129 VLAPAARRPETMGLSAPQRRQWELFRAAGEHPQA-SHALALTLNSKIDPEILGHALDDVT 5187

Query: 61   DRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPA-EFDSIARSERRRPFDLSRGPA 119
             RH  LR  F + D      +V   +  P  E V   A +   +     + P DL     
Sbjct: 5188 SRHEPLRTTFVEVDGI----VVARESVRPTVEVVDVGAGDVGRVVFELAQLPMDLREQSP 5243

Query: 120  LRV-VVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELL---AVXXXXXXXXXXXXXXXX 175
            LRV +VL   G   R ++   H+I VD WS+     +L+   A                 
Sbjct: 5244 LRVHLVLGEDGS--RTLLLVMHYIAVDEWSVVPLLGDLVSAYAARLQGDQPIWDELALTY 5301

Query: 176  XXYIVWL---------AKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLP 226
              Y VW               S  LA W D L G+   + +       + +     + + 
Sbjct: 5302 ADYTVWSDELLGDPLDVDSRASKQLAYWQDALDGIPTSVNLPLPEDDSEPRGDVVSVDID 5361

Query: 227  AADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVG 286
            A   AR+   A R G ++   +  A A VL++     D+  G++V+GR D  P +E M+G
Sbjct: 5362 ADLHARIDALAARTGTSMFMVLQAALAAVLTKAGAGTDLPIGSLVAGRSD--PRLEPMIG 5419

Query: 287  LFINAVPVVHYVSGTEAVVAQCTQVQR---QSSAMRDVSYLSLSE 328
             F N V +    SG+        +V+    ++ + +DVSY+ + +
Sbjct: 5420 SFFNVVLLRTDTSGSPTFAELLGRVREGNLEALSNQDVSYVYVEQ 5464


>tr|B1VQH8|B1VQH8_STRGG Tax_Id=455632 SubName: Full=Putative
            NRPS;[Streptomyces griseus subsp. griseus]
          Length = 5808

 Score =  605 bits (1561), Expect = e-170
 Identities = 525/1562 (33%), Positives = 702/1562 (44%), Gaps = 140/1562 (8%)

Query: 15   SPLQEGLFALHQL-------AEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLR 67
            +PLQEGL  L Q        A D +D+Y +Q  + + G +D + LR + + ++ RH  LR
Sbjct: 4272 TPLQEGLLFLSQYDGPGSTGAGDPLDVYHVQVAIRLTGDLDTDRLRTALRTVVRRHAPLR 4331

Query: 68   AAF------WDRDVPKPVQIVPVHAALPWSERVATPAEFDSIARS--ERRRPFDLSRGPA 119
             AF      W + V    +  P  A L    R     E  +  R+  ERRR FDLS  P 
Sbjct: 4332 TAFTGDGNGWTQRVHTDPE--PEFAVLDLRRRKPREQERRAARRADDERRRRFDLSAPPL 4389

Query: 120  LRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYI 179
            LR  ++  P   +  ++ T HH+++DGWSL +   ELL                    + 
Sbjct: 4390 LRATLVRRPETCE--LVLTGHHLVLDGWSLPLLVRELLHTYAERELPEPPDYVL----HR 4443

Query: 180  VWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLRQWAGR 239
             WL  +D  +A   W D L GV+EP  +  +    Q  P +  + + A  T R+  +   
Sbjct: 4444 AWLDARDEQSAAEAWRDALDGVTEPTRLVPDDPGEQELPDQQTVWVDAELTERIAAFGRE 4503

Query: 240  HGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVS 299
              LTL+T    AW +VLS  T RRDVVFGTVVSGRP ++PG   M+GLF+N VPV   V 
Sbjct: 4504 RELTLSTLTQAAWGLVLSAHTGRRDVVFGTVVSGRPAEVPGATEMIGLFVNTVPVRVTVR 4563

Query: 300  GTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAIRPATT 359
              E + A   ++Q + +A+    +L L+ IQR  G G LFD+L   EN P  D I     
Sbjct: 4564 PQETLAALAARLQDEFTALLPHHHLGLAAIQRAAGHGVLFDTLTALENYPA-DGIPALAG 4622

Query: 360  PDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGERMLTVLRQL 419
              G     +     THYPLT  +                  P   A E+  R+  +LR L
Sbjct: 4623 ATGLGLEEITGRDATHYPLTFAAVPGERLALRVTHRPAAVTP-ARARELAGRVEHLLRVL 4681

Query: 420  PDIGDGTPDDLDIRTAAELKAHGLLAARSA--PTFDTTVWEMFERQVQXXXXXXXXXXXX 477
                D     LD  TAAE   H  L A  A  P      W     + +            
Sbjct: 4682 VTAPDTRVAALDALTAAE---HAELTADRAGPPAPAPRTWARLVAEQRDRRPDAVAVDAP 4738

Query: 478  GVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDV 537
                TYA+L  RA   AG L   G+ P  +VA++LPRS                +LP+D 
Sbjct: 4739 DGSLTYAQLDLRARESAGTLRAAGIRPGQLVAVILPRSVDLVVAQLAVQQAGAAHLPIDP 4798

Query: 538  TLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRS---AAAPTV 594
              P  R+ ++++ A PA  +T    +    TA+ T A   PAA E+ +  +     AP  
Sbjct: 4799 DYPEDRIAAMLQDARPAGILTHRALADRYPTALYTDA-PPPAAAEASAATAPHPRHAPAT 4857

Query: 595  DRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWS 654
            D  P+  AYVIFTSGSTG PKGVV  +  + +  A  AER+                  S
Sbjct: 4858 DVTPDHPAYVIFTSGSTGRPKGVVTPHRGLTALAAAQAERL------GIDDGSRVLQLAS 4911

Query: 655  LSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAG 713
             SFDAS  + ++ L  G  + + +   +     L E IA  ++      P+    L   G
Sbjct: 4912 PSFDASVMETLMALATGATLVVPEPGPLA-GPLLGETIARRRVSHALIPPTALTGLEPDG 4970

Query: 714  LLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMTV-EXXXXXXKDYRKPTIG 772
             LDH L  L +GGEA    L    R      + N YGPTE T              P IG
Sbjct: 4971 -LDH-LRTLIVGGEACTAPL--TARWAPGRRMINAYGPTEATACVTMSAPLAPGATPPIG 5026

Query: 773  TANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPLRP-GQRM 831
            T   G   +V D+ LR VP G  GELY++G  +A+GY+GRP +TA RF A+P  P G RM
Sbjct: 5027 TPLHGVRVHVLDTLLRPVPPGGTGELYVAGPGVAQGYLGRPRLTAERFTAEPGGPRGSRM 5086

Query: 832  YRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDR 891
            YRTGDLV R   G   Y GRAD QVKIRG+RVE GEI AAL+ +P +  AAV VLRQ D 
Sbjct: 5087 YRTGDLVSRTPEGSLLYHGRADDQVKIRGFRVEPGEIVAALQARPEIRAAAV-VLRQDDP 5145

Query: 892  TS---LVGFVV--------WQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANG 940
                 LV ++V          +    D   LR  L   LP +MVP+  V +P LPV ANG
Sbjct: 5146 AGPRRLVAYLVPAAPSGGSRPEAGRLDTAALRTALARVLPDHMVPSAFVGVPGLPVTANG 5205

Query: 941  KLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPHI--DDDLFLFGMD 998
            KLD    D L      + +G TA       E  L  +F E L  +P +  +D  F  G D
Sbjct: 5206 KLD---RDALPAPDFGAAAGDTAPEG--PAEETLAAIFAEVL-GIPSVGAEDSFFTLGGD 5259

Query: 999  SIVAISLVHKARRQGLRVDPRMVLTATTIRQLGA-AIDAAVDSQDAPADA---DYGAVRP 1054
            SI+++ LV +AR  GLR+ PR V   T++R L A A     D    PA +   D G    
Sbjct: 5260 SILSMRLVARARAAGLRLTPREVFELTSVRALAALASGREPDPAAGPAASALPDSGPAPL 5319

Query: 1055 LPMVSWLYEY-GNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRS---------I 1104
             P++ W+ E  G   RF+ ++LL LP GI  ++   +L  +L  H  LR+         +
Sbjct: 5320 TPIMRWIAERPGPTGRFSQSMLLTLPPGITPAATAEVLGAVLRHHAVLRARIDLDAGTFV 5379

Query: 1105 LTETPEGPRLVTRE-PAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAM 1163
            + E  +GP     E P+A  A+                  A+A     +   +DPS G M
Sbjct: 5380 VPEPADGPAPALDEGPSATGAD----------------PGALAREVDELATGLDPSQGLM 5423

Query: 1164 VRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFT 1223
            VRA  + G    A     LLL  HHLAVD VSW I+L DLA AW  +  G  P + P  T
Sbjct: 5424 VRARSYPG---NAGEPGRLLLVVHHLAVDGVSWRILLDDLAQAWGDVSRGRAPHLPPATT 5480

Query: 1224 SYRRWCELMWHRASAPQVQDQRDYWAALVREPD----PALGLRYPDPTRDTWSTLQLTRA 1279
            S+R W   +  +ASA     +   W  ++  PD    PA G   P           L R 
Sbjct: 5481 SFRSWAHALGRQASAR--AGELPVWQGILAAPDRLPAPASGRAEPPALGTVADARHLVRT 5538

Query: 1280 AIPVDVTERVLGAV-RRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADA 1338
                     + GA   R   V++L+L A A AV  W      D AA V    EGHGR   
Sbjct: 5539 LDGAHTRTLLTGAAEHRGARVQDLMLTALARAVREWSGRERVDFAAHV----EGHGREQQ 5594

Query: 1339 VLD-TDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGL 1397
            + D  D + TVGWFT+ +PVRL A AA         +P    D +     HL  +P+ G+
Sbjct: 5595 IEDGADLSRTVGWFTSLYPVRLAATAA---------EPPG--DTLARTRDHLARLPDSGI 5643

Query: 1398 DYGLLRYVD------GVAELVDAVDPQIQFSYLGRLDL----GGVADQPWSLLTGPYLDA 1447
             YGLLRY           E      P I F+YLGR       GG A  P      P    
Sbjct: 5644 GYGLLRYAAQPPAGLRPEETDGPGAPLIAFNYLGRFGTAPTGGGAAWAP-----APGAGV 5698

Query: 1448 LPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAAL 1507
            L    +  L +  A+ ++     T EG  L     W+ A  +      L   WQR + AL
Sbjct: 5699 LGGAVDAGLTMAHAVEINALTRDTPEGPLLDTRLTWAPAALDDRAAHALADCWQRALTAL 5758

Query: 1508 AA 1509
            AA
Sbjct: 5759 AA 5760



 Score =  350 bits (898), Expect = 9e-94
 Identities = 427/1499 (28%), Positives = 607/1499 (40%), Gaps = 171/1499 (11%)

Query: 4    AAPQIEDV-----LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQA 58
            A P +E V     L LSP Q  L+ L +L       Y + FV+ + G VD + L  +   
Sbjct: 2144 ALPALEPVPHEGPLPLSPAQARLWFLSRLQPGTA--YHLPFVLTLTGDVDHDALAAAVGD 2201

Query: 59   MLDRHPNLRAAFWDRDVPKPVQIVPVHAALPWSERVATPAE-FDSIARSERRRPFDLSRG 117
            + +RH  LR  F   D   PVQ + +    P   R A  AE  + +  +    PFDL+  
Sbjct: 2202 LAERHAVLRTVFPAAD-GAPVQHI-LDRPEPVRRRTARSAEEAEELLGALSAEPFDLAAE 2259

Query: 118  PALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXX 177
            P  R  VL+ P  T  R++   HHI  D WS+    T+L A                   
Sbjct: 2260 PPFRATVLAEPDRT--RVLLLIHHIAADEWSVEPLLTDLSAAYRTRLAGGPPGLPPLGVA 2317

Query: 178  YIVWLAKQDRSAALAG---------WMDYLRGVSEPLMVAYEATAGQSKPGK---TELLL 225
            Y  +   Q   A L G         W   LRG    L +  +    ++  G+       L
Sbjct: 2318 YTDYAHWQH--ALLDGGHLDGQAGFWRRTLRGAPAVLDLPTDRPRPETPTGRGGFVPFAL 2375

Query: 226  PAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMV 285
            P    + LR  A    +T       A   +L+ L    D+  G   +GR ++    E ++
Sbjct: 2376 PDEVASGLRALAADAAVTPFMVTQAALCALLAGLGAGDDIPLGVPTAGRGERR--TEELI 2433

Query: 286  GLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLS----LSEIQREHG-RGPLFD 340
            G F+N + +   +SG         +V+       D + L     + E+  E G   PLF 
Sbjct: 2434 GFFVNTLVLRTDLSGDPTFRELLARVRAVDLDAFDHAELPFERVVEELNPERGPANPLFQ 2493

Query: 341  SLFVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTV--VSHLRXXXXXXXXXXXXX 398
             +  ++N        P T P       +       + L V    HL              
Sbjct: 2494 VMLTYQNR----TSVPFTAPGVDAAFTLRETDTAKFDLIVGFTDHLADGSVDGAINYSAD 2549

Query: 399  XXPYLPAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFD----T 454
                     + +R++  L +     D     + + TA E      L  R  P  D     
Sbjct: 2550 LFDATTVRALADRLVAFLARAVARPDTRIGSIGLLTAGE---EDTLLRRWNPAGDHRGAP 2606

Query: 455  TVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPR 514
             V + F R               G   TYAEL AR   LA  L  +GVGPE  VAL+LPR
Sbjct: 2607 PVLDRFARAAADHPAAPALTDG-GDTLTYAELDARTNALARLLMSYGVGPEDRVALLLPR 2665

Query: 515  SERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITE---ADYSQLVGTAVP 571
            S                Y+PVD   P  R+   +R A+PAL +T+   A  +    TA P
Sbjct: 2666 SATLVEAVLAVAKTGAAYVPVDPAHPRDRIAWTLRDAAPALVVTDSATAGRTPATCTA-P 2724

Query: 572  TLALDDPAAVESISRR-----SAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLS 626
             + LD+     S  R+     + A  T  +R + +AY+I+TSGSTG PKGVV T   +  
Sbjct: 2725 VIVLDEEPHAGSRLRQPDGPVADAERTGPQRQDNAAYLIYTSGSTGRPKGVVVTGRNLAR 2784

Query: 627  YFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADR 686
             F   AE  +              H+++  F   W+    LL G  + +      R  D 
Sbjct: 2785 LFDATAEDAFGPDDVWTLF-----HSYAFDFSV-WEMWGALLHGGRLVIVPGAVTRSPDE 2838

Query: 687  LVEGIAIGQIDMIDTTPSMFVQLSAAGL------LDHNLSVLALGGEAINTG-LWDQLRG 739
             +E +    + +++ TPS   QL+ A        L   L ++ LGGEA++   L   LR 
Sbjct: 2839 FLELLHHEGVTVLNQTPSACYQLTEALTAPGSPGLPPALRLVVLGGEALDPARLAPWLRD 2898

Query: 740  LSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTF-----GYVFDSALRMVPDGV 794
                 + N YG TE TV            P  G +  G        YV D  LR VP GV
Sbjct: 2899 PEGPRLVNMYGITETTVHVTTHDLAP-GTPAPGASPVGRAIDDLRVYVLDRRLRPVPPGV 2957

Query: 795  VGELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRAD 853
             GELY++GA L+RGY GR  +TA RFVADP   PG RMYR+GDL R  + G   Y+GRAD
Sbjct: 2958 GGELYVAGAGLSRGYRGRHPLTAERFVADPFGAPGTRMYRSGDLARWSADGVLHYLGRAD 3017

Query: 854  TQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHEDLIKLRA 913
            +QV +RG+RVE  EIE  LR   G   AA  VL ++D  +  G V +          LRA
Sbjct: 3018 SQVSLRGFRVETAEIETVLRDPGGARSAA--VLLREDLPTGPGLVAYTTG-GTPADALRA 3074

Query: 914  GLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERV 973
                RLP+YMVP   V L RLP+  NGKLD  AL  L + A      G A    T  E +
Sbjct: 3075 ACAARLPAYMVPTAFVALDRLPLTNNGKLDRAALP-LPDTAPDGPPTGRA--PRTPHEHL 3131

Query: 974  LCELFEEQLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQ-GLRVDPRMVLTATTIRQLG 1031
            +  L+ E L   P   D+D F  G  S++   L  + R + GL V  R +  A T+  L 
Sbjct: 3132 VARLYGEVLGRAPVAADEDFFALGGHSLLVTRLAGRVRAELGLDVPVRTLFEAPTVAALA 3191

Query: 1032 AAIDAAVDSQDA----PADADYGAVRP--LPMVS-----WLYEY--GNYRRFTHTVLLRL 1078
            A +     +QDA    PA A   AVRP  LP+       W      G+   +   +LLRL
Sbjct: 3192 ARLTGLTRTQDARVPGPAPA---AVRPERLPLSPAQARLWFLHRLGGSALTYAVPLLLRL 3248

Query: 1079 PSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSD 1138
               +D S++   L  L   H+ LR+   E    P                 +  LPE + 
Sbjct: 3249 RGPLDESALGRALAALARRHEILRTCYPEHEGRP----------------VQQVLPEAAP 3292

Query: 1139 DELASAVAH-------AARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAV 1191
              LASA+         A R+  +  D +    +RA    G     D  ++LLL  HH+A 
Sbjct: 3293 VPLASALLDGESAQDAARRLAAEPFDLADRPPLRAHLLTGP---GDERSLLLL-VHHIAY 3348

Query: 1192 DVVSWHIMLGDLA---AAWRSLQAGTPPKILPEFTSYRRWCELMWHR-ASAPQVQDQRDY 1247
            D  S   ++ DLA   AA      G P     ++  Y      +WHR A+A +      Y
Sbjct: 3349 DEASTGPLVRDLARLYAAELDPDHGAPEPPALQYADY-----TLWHREATAAREDGLLAY 3403

Query: 1248 W-AALVREP-DPALGLRYPDPTR--DTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELL 1303
            W  AL   P + +L L  P P    +   +++ T   +P D+  R    + RD G    +
Sbjct: 3404 WRTALAGAPEETSLPLDRPRPAEVDEHGDSVEFT---VPADL-HRAAARLARDNGATLFM 3459

Query: 1304 LAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGA 1363
            +  +A+AV         D   G L++    GR +  L+       G   N   +R     
Sbjct: 3460 VLQSALAVLLTGHGAGHDLPIGTLLS----GRGERALE----ELPGLIANTVVLRTDTSG 3511

Query: 1364 AAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDAVDPQIQFS 1422
            +    E               +++ + A+  D  D+G L +      LVDA+ PQ   S
Sbjct: 3512 SPTFTE---------------LLARVRAVDLDAFDHGDLPF----ERLVDALAPQRSLS 3551



 Score =  335 bits (860), Expect = 2e-89
 Identities = 408/1416 (28%), Positives = 587/1416 (41%), Gaps = 141/1416 (9%)

Query: 12   LALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFW 71
            L LSP Q  L+ LH+L    +  Y++  ++ + GP+D   L R+  A+  RH  LR  + 
Sbjct: 3218 LPLSPAQARLWFLHRLGGSALT-YAVPLLLRLRGPLDESALGRALAALARRHEILRTCYP 3276

Query: 72   DRDVPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSVPGET 131
            + +     Q++P  A +P +  +         AR     PFDL+  P LR  +L+ PG+ 
Sbjct: 3277 EHEGRPVQQVLPEAAPVPLASALLDGESAQDAARRLAAEPFDLADRPPLRAHLLTGPGD- 3335

Query: 132  KRRMIFTAHHILVDGWS---LAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVW-----LA 183
            +R ++   HHI  D  S   L      L A                   Y +W      A
Sbjct: 3336 ERSLLLLVHHIAYDEASTGPLVRDLARLYAAELDPDHGAPEPPALQYADYTLWHREATAA 3395

Query: 184  KQDRSAALAGWMDYLRGVSEPLMVAYEAT--AGQSKPGKT-ELLLPAADTARLRQWAGRH 240
            ++D    LA W   L G  E   +  +    A   + G + E  +PA       + A  +
Sbjct: 3396 RED--GLLAYWRTALAGAPEETSLPLDRPRPAEVDEHGDSVEFTVPADLHRAAARLARDN 3453

Query: 241  GLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSG 300
            G TL   +  A AV+L+      D+  GT++SGR ++   +E + GL  N V +    SG
Sbjct: 3454 GATLFMVLQSALAVLLTGHGAGHDLPIGTLLSGRGER--ALEELPGLIANTVVLRTDTSG 3511

Query: 301  TEA---VVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSLFVFENAPIDDAI 354
            +     ++A+   V   +    D+ +  L +    QR   R P+F    + +NAP     
Sbjct: 3512 SPTFTELLARVRAVDLDAFDHGDLPFERLVDALAPQRSLSRHPIFQVALIHQNAP----- 3566

Query: 355  RPATTPDGAQFLPVEMESLT----HYPLTVVSHLRXXXXXXXXXXXXXXXPYLPAAEIGE 410
               T P G   +  E+           L VV                          +  
Sbjct: 3567 -HRTLPFGPATVEAELVETRAAKFDLTLAVVEEPGTDGLRAALNYRTALFDRPTVEALAH 3625

Query: 411  RMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFER-QVQXXXX 469
            R+ T+L +L     G P D  +    E +A  +L A + P        + +  + Q    
Sbjct: 3626 RLTTLLHRLCT-HPGLPVD-QVPVLDEAEARRVLTASAGPHVPLPGRTLVDLVREQAARS 3683

Query: 470  XXXXXXXXGVRH-TYAELHARACRLAGELAEHGVGPETVVALVLPRSERSXXXXXXXXXX 528
                    G R  +Y E    A RLAG LAEHGV     V + +PRS             
Sbjct: 3684 PAAEALRDGTRSWSYREFDTEADRLAGLLAEHGVRRGDTVVVAVPRSAELVLAVHAVQRA 3743

Query: 529  XXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPTLALDDPAAVESISRRS 588
               YLPVD   P+ARV S ++ A   L IT+   + L G AV  L + D  A E + R +
Sbjct: 3744 GAAYLPVDPAQPAARVSSQLQDAEAVLLITDPA-AALPGEAVGGLPVLDVTADE-VPRFT 3801

Query: 589  AAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSY--FADHAERVYXXXXXXXXXX 646
                    RP   AY++FTSGSTG PKGV   + AV +   +A  A R+           
Sbjct: 3802 TVLD--GPRPADPAYLLFTSGSTGRPKGVRVPHDAVANRLRWAQDAYRLTEEDRVLLKTP 3859

Query: 647  XXXXHAWSLSFDAS-WQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSM 705
                     +FD S W+    LL G  +     ++ RD   +   +   ++  +   PSM
Sbjct: 3860 A--------TFDVSVWELFWPLLAGATLVTAGPDDHRDPVAIARLLREHRVTTVHFVPSM 3911

Query: 706  FVQLS--AAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMA-VYNCYGPTEMTVEXXXXX 762
                +  AA      L  +   GE +       L  L+  A ++N YGPTE  V+     
Sbjct: 3912 LAAFTGTAAPADCATLRRVLASGETLTPAAAAGLLRLAPGAELHNLYGPTEAAVDVTAHP 3971

Query: 763  XK-----DYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRPGMTA 817
                     R P IG     T   V D+ LR  P G  GELYL+GAQLA GY  R  +TA
Sbjct: 3972 VTAADIASGRLP-IGRPVWNTTTLVLDARLRPAPPGAAGELYLAGAQLAYGYHRRAALTA 4030

Query: 818  ARFVADPLRP-GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQP 876
             RFVADP  P G R+YRTGDL R  + G   ++GR D Q+K+RG RVE GEI A L    
Sbjct: 4031 TRFVADPYGPPGSRLYRTGDLARLRADGALEHLGRVDDQIKLRGQRVEPGEIRAVLDAHH 4090

Query: 877  GVHDAAVSVLRQQDR----TSLVGFVVWQDNMHEDLIKLRAGLTE----RLPSYMVPARI 928
            G+  AA +V+  +D     T L+G+VV +     +   L AGL E    RLP+++VP  +
Sbjct: 4091 GI--AAAAVVAHEDTATGVTHLIGYVVPRTG---EGAALPAGLAEHLAARLPAHLVPTAL 4145

Query: 929  VTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPHI 988
            + LP LPV ANGK     LDR A  A    S  T  +  TD E  L  LF E L    HI
Sbjct: 4146 IPLPALPVTANGK-----LDRAALPAPRLTSPETRTAPRTDEELRLAALFAELLR-TEHI 4199

Query: 989  --DDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAID---AAVDSQDA 1043
              DD  F  G DSI++I LV  AR+ GL   P+ V    T+  L A  +    A   +  
Sbjct: 4200 GVDDSFFALGGDSILSIQLVAAARKAGLHFTPQDVFRHRTVAGLLAVAEPTTPAAPPRAL 4259

Query: 1044 PADADYGAV-RPLPMVSWLYEYGNYRRFTHT------------VLLRLPSGIDRSSIELM 1090
            PA  D GA  RP P+   L     Y     T            V +RL   +D   +   
Sbjct: 4260 PAAPDDGAPGRPTPLQEGLLFLSQYDGPGSTGAGDPLDVYHVQVAIRLTGDLDTDRLRTA 4319

Query: 1091 LQLLLDGHDTLRSILTETPEG-PRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAA 1149
            L+ ++  H  LR+  T    G  + V  +P    A   L R   P   +   A       
Sbjct: 4320 LRTVVRRHAPLRTAFTGDGNGWTQRVHTDPEPEFAVLDLRR-RKPREQERRAARRADDER 4378

Query: 1150 RVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRS 1209
            R    + D SA  ++RA   R  E        L+LT HHL +D  S  +++ +L   +  
Sbjct: 4379 R---RRFDLSAPPLLRATLVRRPE-----TCELVLTGHHLVLDGWSLPLLVRELLHTYAE 4430

Query: 1210 LQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVR-EPDPALGLRYPDPTR 1268
             +   P    P++  +R W +    +++A   +D  D      R  PD       PD  +
Sbjct: 4431 RELPEP----PDYVLHRAWLDARDEQSAAEAWRDALDGVTEPTRLVPDDPGEQELPD-QQ 4485

Query: 1269 DTWSTLQLTRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRA-----QDPA 1323
              W         +  ++TER+    R     REL L  + +  A+W  V +     +D  
Sbjct: 4486 TVW---------VDAELTERIAAFGRE----RELTL--STLTQAAWGLVLSAHTGRRDVV 4530

Query: 1324 AGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRL 1359
             G +V+    GR   V     T  +G F N  PVR+
Sbjct: 4531 FGTVVS----GRPAEV--PGATEMIGLFVNTVPVRV 4560



 Score =  325 bits (834), Expect = 2e-86
 Identities = 399/1475 (27%), Positives = 573/1475 (38%), Gaps = 147/1475 (9%)

Query: 22   FALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQI 81
            F      EDG   Y++   +D+   +D   LRR+   +  RH  LR      D     Q+
Sbjct: 1104 FLARSQGEDGS--YNIPLAIDVAARLDPAALRRALGDVAARHEILRTVLPVEDGEAWQQV 1161

Query: 82   VPVHAALPW-SERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSV------PGET--- 131
            + + AA P  +E     A      R+E  RPFD+ R   LR V+ +V      PG     
Sbjct: 1162 LDITAAEPGLAEAHVREARLGERVRAEAARPFDVERETPLRAVLFTVEPDPAEPGSAEPG 1221

Query: 132  ----------KRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYI-- 179
                      ++ ++   HHI  D WSL +   +L A                   +I  
Sbjct: 1222 PCGAETVAPVRQTLLLVLHHIAADEWSLPLLLDDLAAAYAARLDGSDPHPPRLPVDHIDF 1281

Query: 180  -VW-----LAKQDRSAALAGWMDYLRGVSEPLMV--AYEATAGQSKPGKT-ELLLPAADT 230
             +W      A+Q+  A    W   +RG  E L +  A    A    P +T +  + A   
Sbjct: 1282 TLWQQDLVTARQEADAQF--WRTRMRGAPEQLTLPWARPRPARTGGPARTHDFGIDAELH 1339

Query: 231  ARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFIN 290
             R++  A R   T    +  A+A  LS+L    D+V GT V+GR D+   +   VG  IN
Sbjct: 1340 QRVKALARRTRTTTFMVLHAAFAATLSQLGCGDDLVIGTPVAGRDDE--ALRGSVGFLIN 1397

Query: 291  AVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQRE------HGRGPLFDSLFV 344
             +P+   +  T   +    + +    A      L L  I  E       G  PLF  LF 
Sbjct: 1398 TLPLRTRLDATTGFLDLLERTRDDDLAALAHRSLPLERIVAEVNPPRLPGVSPLFQVLFA 1457

Query: 345  FENAPIDDAI------RPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXX 398
                  D A+      RP     GA    ++  +++  P T  +                
Sbjct: 1458 VREEFPDRAVLPGQTGRPRLVATGAAKFDLQC-TVSEDPATGAT--------GQLEYRTE 1508

Query: 399  XXPYLPAAEIGERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWE 458
                  A      +L VL QL         +  + T        + A    P   T++ E
Sbjct: 1509 LWDAAAADRFARALLHVLDQLT-----AHPERPVATTPTGAGGAVAAPEPHPVPATSLAE 1563

Query: 459  MFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS 518
            +   Q                  T+A+L AR+ RLA  LA+ G GP  +V + LPR    
Sbjct: 1564 LCAAQAARTPGRTALVSGAD-EITHADLDARSARLARLLADRGAGPGALVGVSLPRGADL 1622

Query: 519  XXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITE-ADYSQLVGTAVPTLALDD 577
                         +LPVD   P+ R+  ++  A+PAL +T+ A    L       L LDD
Sbjct: 1623 LVTLLAVARTGAAHLPVDPGFPAERIRMLLADAAPALLVTDRATARTLDADPRSVLLLDD 1682

Query: 578  PAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYX 637
            PA V + +  +  AP      +  AYVI TSGSTG PKGVV T AAV+++    A+ +  
Sbjct: 1683 PATVRAAAGAAPLAPRA-AHGDAPAYVIHTSGSTGRPKGVVVTRAAVVNFLLCLADTLRF 1741

Query: 638  XXXXXXXXXXXXXHAWSLSFD-ASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQI 696
                            ++ FD A  +  + L+ G  + L D E++RD   L E I   + 
Sbjct: 1742 HGRERLLAVT------TVGFDIAVLELFLPLVTGATVILADREQVRDPALLAELIDTARP 1795

Query: 697  DMIDTTPSMF-VQLSAAGLLDHNLSVLALGGEAINTGLWDQLRGLSQMAVYNCYGPTEMT 755
              +  TPS++   L  A      L  LA GGEA+   L  +L       V N YGPTE T
Sbjct: 1796 TAMQATPSLWRALLDTAPDAVRGLLALA-GGEALAPDLARRLVAHGADLV-NLYGPTETT 1853

Query: 756  V--EXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARGYVGRP 813
            +          D   P +GT    T   V    L  +P GV GELYL+G  LA+GY+GRP
Sbjct: 1854 IWSTAGRLDATDAEAPHVGTPLWNTRALVLGRGLVPLPVGVTGELYLAGDGLAQGYLGRP 1913

Query: 814  GMTAARFVADPLRP-GQRMYRTGDLVRRLSHGGYAYVGRADTQVKIRGYRVEVGEIEAAL 872
            G TA RF ADP  P G RMYRTGDL R  + G    VGRAD QVKIRG+RVE  E+ AAL
Sbjct: 1914 GQTAERFTADPCGPPGSRMYRTGDLARLRADGALEIVGRADHQVKIRGHRVEPAEVAAAL 1973

Query: 873  RGQPGVHDAAVSVLRQQDRTS------LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPA 926
            R  P V DAAV   R     +      L G     +       ++R  L   LP ++VP 
Sbjct: 1974 RAHPAVEDAAVVAHRGPADPAPRLIAHLTGLTGSPEARTATAARIREELRAVLPGHLVPD 2033

Query: 927  RIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLNAVP 986
              + L  LP+  NGK     LDR A  A    +     + +   E +L  LF + L    
Sbjct: 2034 LCLPLDALPLTPNGK-----LDRAALPAPRPAAAPVGRAPAGQGEELLAALFADLLGLEQ 2088

Query: 987  -HIDDDLFLFGMDSIVAISL-VHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAP 1044
               + D F  G  S++A  L V  A   G  +  R +    T+  L A   A   +  A 
Sbjct: 2089 VGAEADFFALGGHSLLAARLAVRAAEALGRPLSVRQIFDTPTVAALAARPAAPETALPAL 2148

Query: 1045 ADADYGAVRPL-PMVSWLYEYGNYRRFTH---TVLLRLPSGIDRSSIELMLQLLLDGHDT 1100
                +    PL P  + L+     +  T      +L L   +D  ++   +  L + H  
Sbjct: 2149 EPVPHEGPLPLSPAQARLWFLSRLQPGTAYHLPFVLTLTGDVDHDALAAAVGDLAERHAV 2208

Query: 1101 LRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSA 1160
            LR++       P     +    R E V  R        +EL  A++       +  D +A
Sbjct: 2209 LRTVFPAADGAP----VQHILDRPEPVRRRTARSAEEAEELLGALS------AEPFDLAA 2258

Query: 1161 GAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILP 1220
                    FR T         +LL  HH+A D  S   +L DL+AA+R+  AG PP + P
Sbjct: 2259 EPP-----FRATVLAEPDRTRVLLLIHHIAADEWSVEPLLTDLSAAYRTRLAGGPPGLPP 2313

Query: 1221 ---EFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPDPTRDT-WSTLQL 1276
                +T Y  W   +        +  Q  +W   +R     L L    P  +T       
Sbjct: 2314 LGVAYTDYAHWQHAL---LDGGHLDGQAGFWRRTLRGAPAVLDLPTDRPRPETPTGRGGF 2370

Query: 1277 TRAAIPVDVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRA 1336
               A+P +V    L A+  D  V   ++   A+           D   GV  A  G  R 
Sbjct: 2371 VPFALPDEVASG-LRALAADAAVTPFMVTQAALCALLAGLGAGDDIPLGVPTAGRGERR- 2428

Query: 1337 DAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDG 1396
                   T   +G+F N   +R               DP         +++ + A+  D 
Sbjct: 2429 -------TEELIGFFVNTLVLRTDLSG----------DPT-----FRELLARVRAVDLDA 2466

Query: 1397 LDYGLLRYVDGVAELVDAVDP-----QIQFSYLGR 1426
             D+  L +   V EL     P     Q+  +Y  R
Sbjct: 2467 FDHAELPFERVVEELNPERGPANPLFQVMLTYQNR 2501



 Score =  290 bits (742), Expect = 1e-75
 Identities = 384/1409 (27%), Positives = 548/1409 (38%), Gaps = 202/1409 (14%)

Query: 83   PVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVVVLSVPGETKRRMIFTAHHI 142
            P  AAL W E              ER  P D+  G   R  +L   G+ +       HHI
Sbjct: 97   PGTAALDWMEE-------------ERTAPVDMEHGALYRHALLRT-GDERWLWYHRCHHI 142

Query: 143  LVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIV------WLAKQDRSAALAGWMD 196
            L+D +  A     +  +                           +   +  +A    W D
Sbjct: 143  LLDAYGYARVAERVAELYGHACAGTEPPASPFAPLRDAVQEDRRYTDSEQHAADARFWQD 202

Query: 197  YLRGVSEPLMVAYEA-TAGQSKPGKTELLLPAADTARLRQWAGRHGLTLNTAVLFAWAVV 255
             L     P   A  A T    +  ++   L AAD  RL  +A R   T   AV  AWA+ 
Sbjct: 203  LLADRPHPPTPARTAPTRVAPRSLRSRRTLGAADAERLAAFAQRSRATWPEAVTAAWALY 262

Query: 256  LSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQS 315
            L+RLT   + V G  VS R   +     +    +N VP+   V   E V     +V    
Sbjct: 263  LTRLTGTPEAVIGLPVSNRTGSVLARTPVTA--VNVVPLRVAVDEREPVGDLLRRVTATL 320

Query: 316  SAMRDVSYLSLSEIQRE-----HGR---GPLFD------------------SLFVFENAP 349
               R         ++R+     HGR   GP  +                  SL       
Sbjct: 321  RRQRRHQRYRGERLRRDLQLFGHGRRLVGPQLNIKPFATDLAFGDCAGTVHSLAAGAVED 380

Query: 350  IDDAIRPATTPDGAQFL------------PVEMESLTHYPLTVVSHLRXXXXXXXXXXXX 397
            ++  +     PDG   L            P E+++  H   T++  L             
Sbjct: 381  LNVTVGGRGGPDGLTGLDLVLDGNPDLYGPAELDAHLHRFATLLDRLSRAE--------- 431

Query: 398  XXXPYLPAAEIG----ERMLTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFD 453
               P LP A +G       L VL +        PDD D              A +AP  D
Sbjct: 432  ---PDLPGARVGLLDEPERLRVLEEF-----NAPDDGD--------------AEAAPAPD 469

Query: 454  TTVWEMFERQVQXXXXXXXXXXXXGVRH-TYAELHARACRLAGELAEHGVGPETVVALVL 512
                E F  Q +            G  H TYAEL  RA RLA  L   G G  +++A+ L
Sbjct: 470  LV--EGFTDQARRTPHAVALRC--GDAHLTYAELADRAGRLASALTARGAGRGSLIAVAL 525

Query: 513  PRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEADYSQLVGTAVPT 572
            PR E               Y+P+D   P+ R+  ++  + P L +T+  +         T
Sbjct: 526  PRGEALLVALLAVASAGAAYVPLDPRYPADRLRHMLADSRPLLLVTDRAHPWGADLPRLT 585

Query: 573  LALDDP-------AAVESISRRSAAAPT--------VDRRPEQSAYVIFTSGSTGEPKGV 617
            +ALD         A  ES+S  +   P          DRRP   AYVI+TSGSTG PKGV
Sbjct: 586  VALDGTLPDATPGAGTESLSAPADGVPAGPPRSGDPADRRPGDPAYVIYTSGSTGRPKGV 645

Query: 618  VGTNAAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFD-ASWQPMVGLLDGHEIHLF 676
            V    A+ +  A     +                  ++SFD A+ +  V LL G  + L 
Sbjct: 646  VVPRPALANLLAAMGRLL------DLSGEDRLLAVTTVSFDIAALELFVPLLAGATVVLA 699

Query: 677  DAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLAL-GGEAINTGLWD 735
              +++ D   L   I      ++  TPS++  L+ A   D    + AL GGE +   L D
Sbjct: 700  ADDDVSDPFALSALIRSSAPTVMQATPSLWRVLAEAAP-DALGGLRALSGGEPLPADLAD 758

Query: 736  QLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVV 795
             L   +   V N YGPTE T+            P +G     T  +V D  L   P GV 
Sbjct: 759  VLSRHANGLV-NLYGPTETTIWSTAAVLHRGTPPHVGRPVRRTRAHVLDRTLAPAPVGVT 817

Query: 796  GELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADT 854
            GEL+L+G  +A GY+GRP +TA RFVADP   PG RMYRTGDL R    G    +GRAD+
Sbjct: 818  GELHLAGDGVADGYLGRPALTATRFVADPFGAPGARMYRTGDLARYRDDGTLEVLGRADS 877

Query: 855  QVKIRGYRVEVGEIEAALRGQPGVHDAAVSVL------------------RQQDRTSLVG 896
            QVKIRG+RVE GE+EAAL   P V +AAV+ +                   ++      G
Sbjct: 878  QVKIRGHRVEPGEVEAALLAHPSVAEAAVAAVPAPGGDLTLAAYCVLTRTGKEPGAGAAG 937

Query: 897  FVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALT 956
               W D        LR  L ERLP ++VP   V L RLP+  NGK D  AL  +A  A  
Sbjct: 938  EGDWAD-------PLRHALAERLPEHLVPGHFVALERLPLTPNGKTDRAALPAVAPAA-- 988

Query: 957  SVSGGTAVSASTDTERVLCELFEEQL-NAVPHIDDDLFLFGMDSIVAISLVHKAR-RQGL 1014
              + G   +     E +LC+LF   L  +    DDD FL G  S+ A  LV   R R G+
Sbjct: 989  --APGAGRAPRAGAEALLCDLFAAVLGRSEASPDDDFFLLGGHSLSAARLVTALRSRTGV 1046

Query: 1015 RVDPRMVLTATTIRQLGAAID--AAVDSQDAPADADYGAVRPLPMVS---------WLY- 1062
             +  R +    T  +L  A++    ++     A A     RP P            W   
Sbjct: 1047 ELPVRALFDHPTPARLADALERVGGLEGPGRTAGAPPLVRRPRPARPPLSFGQRRLWFLA 1106

Query: 1063 -EYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSIL-TETPEGPR----LVT 1116
               G    +   + + + + +D +++   L  +   H+ LR++L  E  E  +    +  
Sbjct: 1107 RSQGEDGSYNIPLAIDVAARLDPAALRRALGDVAARHEILRTVLPVEDGEAWQQVLDITA 1166

Query: 1117 REP----AAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGT 1172
             EP    A VR   +  R+        ++       A + T + DP+           G 
Sbjct: 1167 AEPGLAEAHVREARLGERVRAEAARPFDVERETPLRAVLFTVEPDPAEPGSAEP-GPCGA 1225

Query: 1173 EHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGT---PPKILPEFTSYRRWC 1229
            E  A     LLL  HH+A D  S  ++L DLAAA+ +   G+   PP++  +   +  W 
Sbjct: 1226 ETVAPVRQTLLLVLHHIAADEWSLPLLLDDLAAAYAARLDGSDPHPPRLPVDHIDFTLWQ 1285

Query: 1230 ELMWHRASAPQVQDQRDYWAALVREPDPALGLRY--PDPTRDTWSTLQLTRAAIPVDVTE 1287
            + +    +A Q  D + +W   +R     L L +  P P R T    +     I  ++ +
Sbjct: 1286 QDL---VTARQEADAQ-FWRTRMRGAPEQLTLPWARPRPAR-TGGPARTHDFGIDAELHQ 1340

Query: 1288 RVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNT 1347
            RV    RR +    ++L A   A  S +     D   G  VA    GR D  L      +
Sbjct: 1341 RVKALARRTRTTTFMVLHAAFAATLS-QLGCGDDLVIGTPVA----GRDDEAL----RGS 1391

Query: 1348 VGWFTNAFPV--RLGAGAAAVDIEQAERD 1374
            VG+  N  P+  RL A    +D+ +  RD
Sbjct: 1392 VGFLINTLPLRTRLDATTGFLDLLERTRD 1420


>tr|D1ACW7|D1ACW7_THECU Tax_Id=471852 SubName: Full=Amino acid
            adenylation domain protein;[Thermomonospora curvata DSM
            43183]
          Length = 3710

 Score =  600 bits (1548), Expect = e-169
 Identities = 496/1575 (31%), Positives = 724/1575 (45%), Gaps = 114/1575 (7%)

Query: 5    APQIEDVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHP 64
            A +  +++  S  Q+ L+ L++  E     Y++   + I G +D   L+ +   +++RH 
Sbjct: 2149 AAERPEIIPPSYAQQRLWFLNRF-EGPSATYNVPVALRITGRLDPAALQAALGDVVERHE 2207

Query: 65   NLRAAFWDRD-VPKPVQIVPVHAALPWSERVATPAEFDSIARSERRRPFDLSRGPALRVV 123
            +LR    D    P+ + + P  A         T  E      S    PFD+S  P LR  
Sbjct: 2208 SLRTVLPDSGGTPRQLVLDPAAARPELQVVQTTEEELPMHLASAAGHPFDISAEPPLRAH 2267

Query: 124  VLSVPGETKRRMIFTAHHILVDGWSLAVFFTELL---AVXXXXXXXXXXXXXXXXXXYIV 180
            + ++  + +  ++   HHI  DGWS+A    +L+   A                   Y +
Sbjct: 2268 LFTLAPD-RHVVLLLMHHIAADGWSMAPLARDLITAYAARAEGRAPGWDPLPVQYADYTL 2326

Query: 181  W----LAKQDRSAAL-----AGWMDYLRGVSEPLMVAYEA---TAGQSKPGKTELLLPAA 228
            W    L  +D  ++L     A W + L  + E + +  +         + G     LPAA
Sbjct: 2327 WQQKLLGSEDDPSSLISRQIAFWKETLADLPEEIALPADRPRPAEASYRGGTVRFHLPAA 2386

Query: 229  DTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLF 288
               RL++ A   G +       A+A +L+R+    DV  G+ ++GR D+   ++ +VG+F
Sbjct: 2387 LRDRLQEVARATGASPFMVAQAAFAALLTRMGAGTDVPIGSPIAGRTDE--ALDDLVGMF 2444

Query: 289  INAVPVVHYVSGTEA---VVAQCTQVQRQSSAMRDVSYLSLSEI---QREHGRGPLFDSL 342
            +N +      SG      +VA+  +    + A +DV +  L E+    R  GR PLF   
Sbjct: 2445 VNMLVFRTDTSGNPTFRELVARVRETDLAAYANQDVPFERLVEVLNPPRHLGRHPLFQVG 2504

Query: 343  FVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXXXXXXXXXXXPY 402
              F+N P      P  T   A+  P+   +     L V++                  P 
Sbjct: 2505 LTFQNNPRARLELPGFT---AEPEPLHAGTARFDLLMVLTETDDGLEGELEYALDLFDPS 2561

Query: 403  LPA--AEIGERMLTVLRQLPDIGDGTPD---DLDIRTAAELKAHG--------------- 442
                 A   ER L  L   PD   G+ +   + + RT     A G               
Sbjct: 2562 TAEDLAARFERFLAALLADPDAPIGSVELLSEAERRTILTDWARGTAQAAQDAQGSVFAD 2621

Query: 443  LLAARSAPTFD-TTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHG 501
            LL   +A   +  T+  +FE QV             G   TY EL+A A RLA  L E G
Sbjct: 2622 LLGVDAASVIERATIPVLFEAQV-LRAPDAVAVTFEGAHLTYGELNAAANRLARLLRERG 2680

Query: 502  VGPETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQASPALAITEAD 561
             GPE  VAL LPRS                Y+P+D   P+ R+  +++ + P LA+T A+
Sbjct: 2681 AGPERFVALALPRSAELVVAIVAVLKAGAAYVPIDPDYPADRIAYMLQDSRPVLAVTTAE 2740

Query: 562  YSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTN 621
             + ++  ++P + LD+    +  +        V  RP+  AYVI+TSGSTG PKGVV  +
Sbjct: 2741 AAGVLPESMPKVLLDEHTLADYSAENLG---DVGLRPDNPAYVIYTSGSTGRPKGVVIPH 2797

Query: 622  AAVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEM 681
              V+   A   +                 H+++  F   W+    LL G  + +      
Sbjct: 2798 RNVVRLLASTEQ----WFGFGPDDVWTLFHSYAFDFSV-WELWGPLLYGGRLVVVPFLTS 2852

Query: 682  RDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLDHNLSVLAL-----GGEAINTGL--- 733
            R  +  ++ +A  ++ +++ TPS F QL AA   D+  + LAL     GGEA+  G    
Sbjct: 2853 RSPEDFLKLLAREKVTVLNQTPSAFYQLMAADR-DNPGAELALRYVIFGGEALELGRLED 2911

Query: 734  WDQLRGLSQMAVYNCYGPTEMTVEXXXXXXKDYRKPT-----IGTANAGTFGYVFDSALR 788
            W          + N YG TE TV         +   +     IGT       YV D  L+
Sbjct: 2912 WYSRHADDAPVLVNMYGITETTVHVSYIALDSFYCASAPGSVIGTGIPDLRLYVLDERLQ 2971

Query: 789  MVPDGVVGELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYA 847
             VP GV+GELY++GA LARGY+ RPG++A RF+ADP   PG RMYRTGDL R L  G   
Sbjct: 2972 PVPPGVIGELYVAGAGLARGYLNRPGLSAERFIADPFGEPGSRMYRTGDLGRWLRDGRLE 3031

Query: 848  YVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQDNMHED 907
            Y+GR+D QV++RG+R+E+GEIEA L   P V D AV V  + DR  LV +VV       D
Sbjct: 3032 YLGRSDQQVQLRGFRIELGEIEATLARHPSVTDVAVIV--RDDR--LVAYVVGD----AD 3083

Query: 908  LIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSAS 967
            + +LR      LP YMVPA +V L  LP+  NGKLD  AL   A D    VS     +  
Sbjct: 3084 VAELRRFAGRSLPDYMVPATVVFLDALPLTVNGKLDRKALP--APDFSAQVSSR---APR 3138

Query: 968  TDTERVLCELFEEQLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATT 1026
             + E +L  LF E L      IDD  F  G DSI+AI LV +AR+ GL + PR V    T
Sbjct: 3139 NEREEILAGLFAEVLGLERVGIDDGFFDLGGDSIIAIQLVSRARQAGLVISPREVFQHQT 3198

Query: 1027 IRQLGAAIDAAVD--SQDAPADADYGAVRPLPMVSWLYEYGN-YRRFTHTVLLRLPSGID 1083
            + +L A    A D  ++  P  A  G V   P++ WL E G  +  F  +VLLR P G+D
Sbjct: 3199 VEELAAIARNATDEAAETEPPGAGVGPVPATPIMHWLRERGGEHSGFHQSVLLRTPGGLD 3258

Query: 1084 RSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELAS 1143
               +   LQ +LD HD LR       +G + V R   +V A  ++ R+ +     D++A 
Sbjct: 3259 LGHLTGALQAVLDHHDMLR---LRIDDGWQPVVRPAGSVDAAALVHRVDIAGLDGDKIAE 3315

Query: 1144 AVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPA--NILLLTAHHLAVDVVSWHIMLG 1201
             VA  A    D++DP+ G M + +W       A PA    LL+  HHL VD VSW I+L 
Sbjct: 3316 VVAQQAAAARDRLDPAGGVMAQLVWLD-----AGPAAQGRLLVMLHHLVVDGVSWRILLP 3370

Query: 1202 DLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGL 1261
            DL  AW ++ AG  P++ P  TS+RRW + +   A+ P+   + D W  ++  P+  LG 
Sbjct: 3371 DLVTAWAAIAAGQTPRLEPVGTSFRRWAQRLVAEATDPERVAELDTWIGILEGPNAKLGD 3430

Query: 1262 RYPDPTRDTWSTLQLTRAAIPVDVTERVLGAV--RRDQGVRELLLAATAMAVASWRRVRA 1319
            R  DP  D  +  +     +P +VTE +L +V      GV + LL   A+AVA WRR R 
Sbjct: 3431 RRLDPAVDVAARARSLSLTLPPEVTEPLLTSVPAAYHAGVDDALLTGLALAVAKWRRDRG 3490

Query: 1320 QDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQ 1379
                +GVL+ LEGHGR +     D + TVGWFT   PVRL  G  AV  E+      A  
Sbjct: 3491 -GKGSGVLIDLEGHGRQEIFPGVDLSRTVGWFTTIHPVRLDPG--AVPWEEVTAGSAALG 3547

Query: 1380 DLVHSVVSHLEAIPNDGLDYGLLRYVDGVA--ELVDAVDPQIQFSYLGRLDLGGVADQPW 1437
                 V   L  +P++G+ YGLLR+++     EL D   PQI F+YLGR+  GG  ++ W
Sbjct: 3548 TAFKQVKEQLRQVPDNGIGYGLLRHLNPATAEELADLPRPQIAFNYLGRVAPGG--EEDW 3605

Query: 1438 SLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLT 1497
            +L      +  P   +P LP+   L ++        G +L   W W D V     +  L 
Sbjct: 3606 ALAP----EEPPSGEDPRLPMAHVLEINAVTRDLPGGPELTATWSWPDGVLPEDQVRALA 3661

Query: 1498 GLWQRGIAALAAGLD 1512
              W   +  L A L+
Sbjct: 3662 EAWFAALRGLVAHLE 3676



 Score =  543 bits (1399), Expect = e-152
 Identities = 512/1568 (32%), Positives = 704/1568 (44%), Gaps = 142/1568 (9%)

Query: 10   DVLALSPLQEGLFALHQLAEDGVDLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAA 69
            ++L LS  Q  ++   QL      +   Q++ +I+G ++  LL   A+   D  P L   
Sbjct: 5    ELLPLSAAQRSVWYAQQLNPQ-TPICIAQYI-EIEGALEPGLLDEVARLAADETPGLHIR 62

Query: 70   FWDRDVPKPVQIVP--VHAALPWSERVATPAEFDSIA------RSERRRPFDLSRGPALR 121
              +RD   P QIVP  V A +P    V   AE D +A      R++   P DL      R
Sbjct: 63   LVERD-GIPYQIVPEGVQATIP---TVDFTAEADPMAAAQEWMRADMAAPMDLFGERLYR 118

Query: 122  VVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXXXXXYIVW 181
            + VL +  + +      AHHI VDG+  A+    +  V                  Y   
Sbjct: 119  MAVLRLAPD-RHLWYLRAHHICVDGFGGALIAARVAEVYTDLAEGRGYRPGSLGS-YREL 176

Query: 182  LAK-----------QDRS---------AALAGWMDYLRGVSEPLMVAYEATAGQSKPGKT 221
            LA+           QDR+           + G   ++  V  P M    AT         
Sbjct: 177  LAEEEAYRSSERFQQDRAYWTERFADLPEVGGLSRHVGKVVAPSMDFVRATTA------- 229

Query: 222  ELLLPAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPG- 280
               L   D+ RL + A           + A A  ++ +T   DVV G  V+GR  +L   
Sbjct: 230  ---LGPDDSRRLAEAARALRSATPALAIAATAAYMAAMTGTDDVVLGLAVTGRTTELARQ 286

Query: 281  ----VETMVGLFINAVPVVHYVSGTEAVVAQCT-----QVQRQSSAMRDVSYLSLSEIQR 331
                +  +V L ++  P +     T AV          Q  R+   MRD+  L  +E +R
Sbjct: 287  TPTMMSNIVPLRVSVRPSMTVAELTRAVSRATARALRHQRYRREDLMRDLGLLGGAE-RR 345

Query: 332  EHGRGPLFDSLFVFENAPIDDAIRPATTPDGAQFLPVEMESLTHYPLTVVSHLRXXXXXX 391
             +G         V    P D   R       A  L + +     +      ++       
Sbjct: 346  LYGA--------VVNIMPFDYTARFGEARARAHALALGLTEDLSF------NIHDGLDGR 391

Query: 392  XXXXXXXXXPYLPAAEI----GERMLTVLRQLPDIG-DGTPDDLDIRTAAELKA--HGLL 444
                     P L  AE      ER +  L+++ + G D T   LD+  A E     H   
Sbjct: 392  GTRIDLDGHPELYTAEEIAAHHERHVRFLQRMAEAGPDATLASLDLLGAQERHTVLHRWN 451

Query: 445  AARSAPTFDTTVWEMFERQVQXXXXXXXXXXXXGVRHTYAELHARACRLAGELAEHGVGP 504
               +  T DT V   F RQV                 TYAEL+ RA RLA  L   GVGP
Sbjct: 452  DTATGRTPDTVVGR-FARQVAAAPDAIAVRAGETTL-TYAELNERANRLAHRLIGLGVGP 509

Query: 505  ETVVALVLPRSERSXXXXXXXXXXXXXYLPVDVTLPSARVESIVRQA-SPALAITEADYS 563
            ET VA+++ RS                Y+PV    P+ RV  ++    +P L    A   
Sbjct: 510  ETPVAVLVDRSPELIVASLAILKTGGYYVPVHHGYPAERVAWLMADTGAPVLVCDRAMAG 569

Query: 564  QLVGTAVPTLALD-DPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPKGVVGTNA 622
            +  G     L +D DP     ++ + A  P V   PEQ AY IFTSGSTG PKGV   + 
Sbjct: 570  RAAGLDATVLVVDADPL----LAAQPATDPGVPVHPEQLAYGIFTSGSTGHPKGVAIRHR 625

Query: 623  AVLSYFADHAERVYXXXXXXXXXXXXXXHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMR 682
             V+ +  D A  ++              HA+  S   +W  ++G        +     + 
Sbjct: 626  DVVDFVTDPALVMHPGERVLVHTA----HAFDASTVETWAALLG----GATCVVAEPGLV 677

Query: 683  DADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLLD-HNLSVLALGGEAINTGLWDQLR-GL 740
            DAD L   +A G +  +  T S+F  ++A       +L  +  GGEA +     +++   
Sbjct: 678  DADALARAVAGGGLTRMFLTTSLFNLVAAERPQALASLREVHTGGEAASAAAMRRVQEAC 737

Query: 741  SQMAVYNCYGPTEMT----VEXXXXXXKDYRKPTIGTANAGTFGYVFDSALRMVPDGVVG 796
              + + N YGPTE T    +       +D     IG   A T  YV D ALR VP GV G
Sbjct: 738  PALRIANVYGPTETTTYSSIHYVDDLPEDATSVPIGRPLADTRLYVLDEALRPVPPGVPG 797

Query: 797  ELYLSGAQLARGYVGRPGMTAARFVADPL-RPGQRMYRTGDLVRRLSHGGYAYVGRADTQ 855
            ELY++G  LARGY+ RP +TA RFVA P   PG+RMYRTGDLVR    G   Y+ RAD Q
Sbjct: 798  ELYIAGTGLARGYLNRPALTAERFVACPFGAPGERMYRTGDLVRWNDDGTLEYLDRADQQ 857

Query: 856  VKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTS---LVGFVVWQDNMHEDLIKLR 912
            VKIRG+R+E+GEIE AL   P V  AAV  + ++DR     LVG+VV       D   LR
Sbjct: 858  VKIRGFRIELGEIETALAAHPDVAHAAV--IAREDRPGDKRLVGYVVPAAGAAPDPAGLR 915

Query: 913  AGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDALTSVSGGTAVSASTDTER 972
            A L  RLP YMVPA ++ L  LP+  NGKLD  AL   A D  ++       +  T  E 
Sbjct: 916  AHLARRLPEYMVPAAVMVLDTLPLTGNGKLDRRALP--APD-YSAAEERPHRAPRTPVEE 972

Query: 973  VLCELFEEQLNAVP-HIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLG 1031
             LC LF E L      +DD  F  G DSIVA+ LV +AR+ GL + PR V    T+ +L 
Sbjct: 973  TLCALFAEVLGVERIGLDDGFFDLGGDSIVAMRLVSRARKAGLVISPREVFQYPTVEELA 1032

Query: 1032 AAI---DAAVDSQDAPADADYGAVRPLPMVSWLYEYGNYRR-FTHTVLLRLPSGIDRSSI 1087
            A +   D    ++ AP D+  G +   P++ WL E G     F+  V+LR+P+G+D   +
Sbjct: 1033 AVVRTRDEEETAEQAP-DSGVGPLTATPIMRWLRELGGPTAGFSQNVVLRVPAGLDTGHL 1091

Query: 1088 ELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAH 1147
               LQ +LD HD LR  + E P+G  L    P ++ A   + R+ +P+  D  L  AVA 
Sbjct: 1092 TAALQAVLDHHDALR--IRELPDGG-LEIPPPGSLDAAGCVRRVPVPDPGD--LQQAVAA 1146

Query: 1148 AARVVTDQIDPSAGAMVRAIWFRGTEHRADPA--NILLLTAHHLAVDVVSWHIMLGDLAA 1205
                   ++DPSAG M + +W       A PA    LLL  HHLAVD VSW I+L DL  
Sbjct: 1147 ELEAARRRLDPSAGIMAQLVWLD-----AGPAAQGRLLLVLHHLAVDGVSWRILLPDLVT 1201

Query: 1206 AWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAALVREPDPALGLRYPD 1265
            A ++   G P ++ P  TSYRRW EL+   A AP+   +  +W  ++   D  LG R  D
Sbjct: 1202 ALQAAADGRPAELDPVGTSYRRWAELLTEEARAPERVAELSHWKDVLSGGDAPLGDRPLD 1261

Query: 1266 PTRDTWSTLQLTRAAIPVDVTERVLG-AVRRDQG-VRELLLAATAMAVASWRRVRAQDPA 1323
            P  DT +T       +  DVT R+LG A     G   ++LLAA A A+A W R R +  A
Sbjct: 1262 PAVDTHATAARLEVELDADVTARLLGEAPAAFHGRANDVLLAAFAAALAHWHRGRGRG-A 1320

Query: 1324 AGVLVALEGHGRADAVLDTDTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVH 1383
              VL+ LEGHGRA+     D T TVGWFT+ +PVRL  G  AVD          A   V 
Sbjct: 1321 GPVLLDLEGHGRAELRPGIDLTRTVGWFTSKYPVRLDVG--AVDWASLCSGGPDAARAVK 1378

Query: 1384 SVVSHLEAIPNDGLDYGLLRYVD--GVAELVDAVDPQIQFSYLGRLDLGGVADQPWSLLT 1441
             V   L A+P DGL +GLLR+++     EL     PQ+ F+YLG+++ G      WS+  
Sbjct: 1379 RVKEQLRAVPGDGLGFGLLRHLNEQTAPELAALPAPQVVFNYLGQVESG---SGDWSV-- 1433

Query: 1442 GPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLW- 1500
                 AL    +P +PL  AL +   V  T +G  L   W W   +   +D+  L   W 
Sbjct: 1434 AAEAGALSGGADPQMPLPHALAVDALVRDTGDGPALSATWTWPAGLLTEADVRELAQAWL 1493

Query: 1501 --QRGIAA 1506
               RGIAA
Sbjct: 1494 DALRGIAA 1501



 Score =  248 bits (632), Expect = 6e-63
 Identities = 152/386 (39%), Positives = 215/386 (55%), Gaps = 16/386 (4%)

Query: 4    AAPQIEDVLALSPLQEGLFALHQL----AEDGVDLYSMQFVVDIDGPVDLELLRRSAQAM 59
            A P +ED+  ++PLQ+GL+  H L    AE   D+Y+ Q ++D+DG +D   LR +A+A+
Sbjct: 1532 AHPDLEDIWPVAPLQQGLY-FHALLAAEAEGVTDVYTGQLILDLDGDLDEAALREAARAL 1590

Query: 60   LDRHPNLRAAFWDRDVPKPVQIV--PVHAALPWSERVATPAEFDSIAR---SERRRPFDL 114
              RHP LR AF       P+Q+V     A   W     + A+ +++ +    ER RPFDL
Sbjct: 1591 PGRHPALRTAFVQGADGTPLQVVLRGDRAEPAWRHLDLSGADEETVRQVMAEERNRPFDL 1650

Query: 115  SRGPALRVVVLSVPGETKRRMIFTAHHILVDGWSLAVFFTELLAVXXXXXXXXXXXXXXX 174
            +R P LR  +L++ GE + R++ + HHI +DGWS+ V   ELLA                
Sbjct: 1651 TRPPFLRFALLTL-GERRHRLLLSFHHIALDGWSMPVLAGELLA----RYTGQEPPRAPA 1705

Query: 175  XXXYIVWLAKQDRSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGKTELLLPAADTARLR 234
               Y+ WL  +D + A A W   L G +  L+    A      P KT + LPA    RL+
Sbjct: 1706 YKDYLAWLTDRDPAEARAAWRAALEGATGTLIAPAAADRPPVPPDKTRIELPAGLGERLQ 1765

Query: 235  QWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQLPGVETMVGLFINAVPV 294
             WA RHGLT NT +   W ++L+RLT R DV+FG  VSGRP +LPGVE MVGLFIN +PV
Sbjct: 1766 GWARRHGLTPNTLMQGVWGLLLARLTGRDDVIFGATVSGRPPELPGVEQMVGLFINTLPV 1825

Query: 295  VHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLSEIQREHGRGPLFDSLFVFENAPIDDAI 354
               ++  E V A  T++QR+ + +    +L L EI R  G G LFD++ VFEN P+D ++
Sbjct: 1826 RVRLNPDETVAAFLTRLQREQAELLPHHHLGLGEIHRLAGGGALFDTMTVFENYPLDSSL 1885

Query: 355  RPATTPDGAQFLPVEMESLTHYPLTV 380
              A   D  Q    ++   THYPLT+
Sbjct: 1886 LGARIGD-LQLSGADLLDATHYPLTL 1910



 Score =  119 bits (298), Expect = 3e-24
 Identities = 199/773 (25%), Positives = 310/773 (40%), Gaps = 135/773 (17%)

Query: 795  VGELYLSGAQLARGYVGRPGMTAARFVADPLRPGQRMY-RTG---DLVRRLSHGGYAYVG 850
            +G+L LSGA L          T      D + PG+RM+ R G   D++ R S G  A + 
Sbjct: 1890 IGDLQLSGADLLDA-------THYPLTLDVV-PGERMHLRLGHRPDVLDRESAGHLAALL 1941

Query: 851  RA-------DTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTS---------- 893
             A       D   KI    +  GE  AALR       AA   L  Q   +          
Sbjct: 1942 PALIETVIDDATRKIADLDLPDGEHAAALR-------AAFQKLAAQQSPADTGRAAPAPV 1994

Query: 894  --LVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLA 951
              LV +VV       D  +LRA + E LP  MVPA +V +  LP+  NGK+D  AL +  
Sbjct: 1995 KKLVAYVVPAPGAQIDPEELRAFVREHLPETMVPAAVVMMDDLPLTPNGKVDTKALPK-- 2052

Query: 952  EDALTSVSGGTAVSASTDTERVLCELFEEQLNAVPH--IDDDLFLFGMDSIVAISLVHKA 1009
                 +V+     +  T  E +LC +F + L  +P   ID++ F  G DS++A+ +V + 
Sbjct: 2053 --PDLTVTAEEHRAPRTPREEILCGIFADLL-GLPQVGIDENFFALGGDSLLAMRVVSRV 2109

Query: 1010 RRQ-GLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPADADYGAVRPLPMVS--------- 1059
            R   G  +  R + TA T+ +L A +           +   GA RP P+V+         
Sbjct: 2110 RATLGAELPIRALFTAPTVAELAALL----------GEEGSGAARP-PLVAAERPEIIPP 2158

Query: 1060 -------WLYE--YGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPE 1110
                   W      G    +   V LR+   +D ++++  L  +++ H++LR++L ++  
Sbjct: 2159 SYAQQRLWFLNRFEGPSATYNVPVALRITGRLDPAALQAALGDVVERHESLRTVLPDSGG 2218

Query: 1111 GPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFR 1170
             PR +  +PAA R E  + + T  E     LASA  H         D SA   +RA  F 
Sbjct: 2219 TPRQLVLDPAAARPELQVVQ-TTEEELPMHLASAAGH-------PFDISAEPPLRAHLFT 2270

Query: 1171 GTEHRADPANILLLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILP---EFTSYRR 1227
                 A   +++LL  HH+A D  S   +  DL  A+ +   G  P   P   ++  Y  
Sbjct: 2271 ----LAPDRHVVLLLMHHIAADGWSMAPLARDLITAYAARAEGRAPGWDPLPVQYADYTL 2326

Query: 1228 WCELMWHRASAPQ--VQDQRDYWAALVRE--PDPALGLRYPDPTRDTWSTLQLTRAAIPV 1283
            W + +      P   +  Q  +W   + +   + AL    P P   ++      R  +P 
Sbjct: 2327 WQQKLLGSEDDPSSLISRQIAFWKETLADLPEEIALPADRPRPAEASYRG-GTVRFHLPA 2385

Query: 1284 DVTERVLGAVRRDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTD 1343
             + +R L  V R  G    ++A  A A    R     D   G  +A    GR D  LD  
Sbjct: 2386 ALRDR-LQEVARATGASPFMVAQAAFAALLTRMGAGTDVPIGSPIA----GRTDEALD-- 2438

Query: 1344 TTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLR 1403
              + VG F N    R               +P   + +     + L A  N  + +    
Sbjct: 2439 --DLVGMFVNMLVFRTDTSG----------NPTFRELVARVRETDLAAYANQDVPF---- 2482

Query: 1404 YVDGVAELVDAVDPQIQFSYLGRLDLGGVA----DQPWSLLTGPYLDALPIDPEPDLPLR 1459
                   LV+ ++P     +LGR  L  V     + P + L  P   A   +PEP     
Sbjct: 2483 -----ERLVEVLNPP---RHLGRHPLFQVGLTFQNNPRARLELPGFTA---EPEPLHAGT 2531

Query: 1460 FALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD 1512
               +L + +  T +G  L G   ++  +F+ S  + L   ++R +AAL A  D
Sbjct: 2532 ARFDLLMVLTETDDG--LEGELEYALDLFDPSTAEDLAARFERFLAALLADPD 2582



 Score = 46.2 bits (108), Expect = 0.036
 Identities = 94/385 (24%), Positives = 138/385 (35%), Gaps = 76/385 (19%)

Query: 1070 FTHTVLLRLPSGIDRSSIELMLQLLLDGHDTLRSILTETPEGPRL--VTREPAAVRAEDV 1127
            +T  ++L L   +D +++    + L   H  LR+   +  +G  L  V R     RAE  
Sbjct: 1566 YTGQLILDLDGDLDEAALREAARALPGRHPALRTAFVQGADGTPLQVVLRGD---RAEPA 1622

Query: 1128 LTRITLPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAH 1187
               + L  G+D+E    V    R      D +    +R       E R    + LLL+ H
Sbjct: 1623 WRHLDL-SGADEETVRQVMAEER--NRPFDLTRPPFLRFALLTLGERR----HRLLLSFH 1675

Query: 1188 HLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDY 1247
            H+A+D  S  ++ G+L A +     G  P   P +  Y  W   +  R  A    + R  
Sbjct: 1676 HIALDGWSMPVLAGELLARY----TGQEPPRAPAYKDYLAW---LTDRDPA----EARAA 1724

Query: 1248 WAALVREPD-----PALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVRRD------ 1296
            W A +         PA   R P P          TR  +P  + ER+ G  RR       
Sbjct: 1725 WRAALEGATGTLIAPAAADRPPVPP-------DKTRIELPAGLGERLQGWARRHGLTPNT 1777

Query: 1297 --QGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDTDTTNTVGWFTNA 1354
              QGV  LLLA         R     D   G  V+    GR   +   +    VG F N 
Sbjct: 1778 LMQGVWGLLLA---------RLTGRDDVIFGATVS----GRPPELPGVE--QMVGLFINT 1822

Query: 1355 FPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGVAELVDA 1414
             PVR+          +   D   A  L        E +P+  L  G +  + G   L D 
Sbjct: 1823 LPVRV----------RLNPDETVAAFLTRLQREQAELLPHHHLGLGEIHRLAGGGALFDT 1872

Query: 1415 --------VDPQIQFSYLGRLDLGG 1431
                    +D  +  + +G L L G
Sbjct: 1873 MTVFENYPLDSSLLGARIGDLQLSG 1897


  Database: Amellifera_nr
    Posted date:  Feb 5, 2010  5:10 AM
  Number of letters in database: 3,846,993,858
  Number of sequences in database:  11,275,203
  
Lambda     K      H
   0.320    0.136    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11275203
Number of Hits to DB: 10,747,429,683
Number of extensions: 445996641
Number of successful extensions: 1215393
Number of sequences better than 10.0: 18995
Number of HSP's gapped: 1149792
Number of HSP's successfully gapped: 32734
Length of query: 1512
Length of database: 3,846,993,858
Length adjustment: 151
Effective length of query: 1361
Effective length of database: 2,144,438,205
Effective search space: 2918580397005
Effective search space used: 2918580397005
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 87 (38.1 bits)