BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_3694 (439 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HM90|B2HM90_MYCMM Tax_Id=216594 (mbtC)SubName: Full=Polyket... 769 0.0 tr|A0PTV1|A0PTV1_MYCUA Tax_Id=362242 (mbtC)SubName: Full=Polyket... 766 0.0 tr|B1MPF0|B1MPF0_MYCA9 Tax_Id=561007 SubName: Full=Putative poly... 553 e-155 tr|Q5Z1T2|Q5Z1T2_NOCFA Tax_Id=37329 (nbtB)SubName: Full=Putative... 470 e-130 tr|D0L276|D0L276_GORB4 Tax_Id=526226 SubName: Full=Beta-ketoacyl... 414 e-113 tr|A3Q280|A3Q280_MYCSJ Tax_Id=164757 SubName: Full=Beta-ketoacyl... 395 e-108 tr|A4T2D8|A4T2D8_MYCGI Tax_Id=350054 SubName: Full=Beta-ketoacyl... 394 e-107 tr|Q1B6A9|Q1B6A9_MYCSS Tax_Id=164756 SubName: Full=Beta-ketoacyl... 391 e-106 tr|A1UIR7|A1UIR7_MYCSK Tax_Id=189918 SubName: Full=Beta-ketoacyl... 391 e-106 tr|A1TBS8|A1TBS8_MYCVP Tax_Id=350058 SubName: Full=Beta-ketoacyl... 386 e-105 tr|A0R0U7|A0R0U7_MYCS2 Tax_Id=246196 SubName: Full=Polyketide sy... 385 e-105 tr|A0QE92|A0QE92_MYCA1 Tax_Id=243243 SubName: Full=Erythronolide... 381 e-104 tr|Q73XY3|Q73XY3_MYCPA Tax_Id=1770 (mbtC)SubName: Full=MbtC;[Myc... 380 e-103 tr|Q7TYQ5|Q7TYQ5_MYCBO Tax_Id=1765 (mbtC)SubName: Full=POLYKETID... 372 e-101 tr|P71718|P71718_MYCTU Tax_Id=1773 (mbtC)SubName: Full=POLYKETID... 372 e-101 tr|C6DNA2|C6DNA2_MYCTK Tax_Id=478434 SubName: Full=Polyketide sy... 372 e-101 tr|C1AQU5|C1AQU5_MYCBT Tax_Id=561275 (mbtC)SubName: Full=Polyket... 372 e-101 tr|A5U575|A5U575_MYCTA Tax_Id=419947 (mbtC)SubName: Full=Polyket... 372 e-101 tr|A1KL72|A1KL72_MYCBP Tax_Id=410289 (mbtC)SubName: Full=Polyket... 372 e-101 tr|Q7D789|Q7D789_MYCTU Tax_Id=1773 SubName: Full=Polyketide synt... 372 e-101 tr|A5WPZ7|A5WPZ7_MYCTF Tax_Id=336982 SubName: Full=Polyketide sy... 372 e-101 tr|A4KJD2|A4KJD2_MYCTU Tax_Id=395095 SubName: Full=Polyketide sy... 372 e-101 tr|C2AVC8|C2AVC8_TSUPA Tax_Id=521096 SubName: Full=Beta-ketoacyl... 362 4e-98 tr|O54593|O54593_AMYMD Tax_Id=33910 (rifE)SubName: Full=RifE; Su... 317 2e-84 tr|B4VAJ6|B4VAJ6_9ACTO Tax_Id=465541 SubName: Full=Polyketide sy... 310 2e-82 tr|B1W485|B1W485_STRGG Tax_Id=455632 (pks1-1)SubName: Full=Putat... 309 4e-82 tr|Q8KPW5|Q8KPW5_9ACTO Tax_Id=201500 (gerSI)SubName: Full=Putati... 309 5e-82 tr|Q2PC83|Q2PC83_STRAH Tax_Id=285531 (rubA)SubName: Full=Putativ... 308 9e-82 tr|C1YLQ5|C1YLQ5_NOCDA Tax_Id=446468 SubName: Full=Polyketide sy... 308 9e-82 tr|Q6W5P6|Q6W5P6_9ACTO Tax_Id=206662 (fscD)SubName: Full=FscD;[S... 306 3e-81 tr|Q5SFB4|Q5SFB4_STRBI Tax_Id=1896 (chmGI)SubName: Full=Polyketi... 306 3e-81 tr|Q1L0S6|Q1L0S6_STRHY Tax_Id=285527 SubName: Full=NapC;[Strepto... 306 4e-81 tr|Q82QT4|Q82QT4_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular... 305 6e-81 tr|Q93H87|Q93H87_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular... 305 6e-81 tr|Q0R4M8|Q0R4M8_STRAT Tax_Id=1890 SubName: Full=ChlA1;[Streptom... 305 6e-81 tr|A1YAM7|A1YAM7_AMYOR Tax_Id=31958 SubName: Full=Polyketide syn... 305 6e-81 tr|O33954|O33954_STRFR Tax_Id=1906 (tylG)SubName: Full=Tylactone... 305 1e-80 tr|Q9S0R8|Q9S0R8_STRAW Tax_Id=33903 (aveA1)SubName: Full=Type I ... 304 1e-80 tr|A8LUX2|A8LUX2_SALAI Tax_Id=391037 SubName: Full=Beta-ketoacyl... 304 1e-80 tr|Q1MX81|Q1MX81_9ACTO Tax_Id=299254 (tmnA1)SubName: Full=Type I... 304 1e-80 tr|O54666|O54666_AMYMD Tax_Id=33910 (rifA)SubName: Full=RifA; Su... 304 1e-80 tr|B6ZIR3|B6ZIR3_STRPT Tax_Id=58346 (pldAII)SubName: Full=Polyke... 304 1e-80 tr|A1YAN0|A1YAN0_AMYOR Tax_Id=31958 SubName: Full=Polyketide syn... 304 2e-80 tr|Q93HE5|Q93HE5_STRAW Tax_Id=33903 (pks5)SubName: Full=Modular ... 302 5e-80 tr|Q1L0S5|Q1L0S5_STRHY Tax_Id=285527 SubName: Full=NapD;[Strepto... 302 6e-80 tr|Q30CS0|Q30CS0_STRAU Tax_Id=1894 (lipPks3)SubName: Full=LipPks... 301 8e-80 tr|Q0QMQ1|Q0QMQ1_9ACTO Tax_Id=270689 SubName: Full=Polyketide sy... 301 8e-80 tr|B3TMQ8|B3TMQ8_9ACTO Tax_Id=46161 SubName: Full=Polyketide syn... 301 8e-80 tr|C3VLV4|C3VLV4_9ACTO Tax_Id=639005 (becA)SubName: Full=Polyket... 301 1e-79 tr|B5L6K8|B5L6K8_MICCH Tax_Id=1874 SubName: Full=Putative type I... 301 1e-79 >tr|B2HM90|B2HM90_MYCMM Tax_Id=216594 (mbtC)SubName: Full=Polyketide synthase MbtC;[Mycobacterium marinum] Length = 439 Score = 769 bits (1986), Expect = 0.0 Identities = 388/439 (88%), Positives = 388/439 (88%) Query: 1 MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV 60 MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV Sbjct: 1 MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV 60 Query: 61 SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG 120 SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG Sbjct: 61 SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG 120 Query: 121 STAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDT 180 STAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDT Sbjct: 121 STAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDT 180 Query: 181 XXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA 240 VREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA Sbjct: 181 ACASSLSALHLAATAVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA 240 Query: 241 TGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKT 300 TGTVWGEGAGMVLV TNHNGKGKPILVPRVRAQEQVIRKT Sbjct: 241 TGTVWGEGAGMVLVERESRARREGRRIYGRIAAIRTNHNGKGKPILVPRVRAQEQVIRKT 300 Query: 301 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQXXXX 360 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQ Sbjct: 301 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQAASG 360 Query: 361 XXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFG 420 QHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFG Sbjct: 361 ILALIKLLLAGQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFG 420 Query: 421 AGGANAHAIISMPAAGVGQ 439 AGGANAHAIISMPAAGVGQ Sbjct: 421 AGGANAHAIISMPAAGVGQ 439 >tr|A0PTV1|A0PTV1_MYCUA Tax_Id=362242 (mbtC)SubName: Full=Polyketide synthase MbtC;[Mycobacterium ulcerans] Length = 439 Score = 766 bits (1977), Expect = 0.0 Identities = 386/439 (87%), Positives = 386/439 (87%) Query: 1 MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV 60 MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV Sbjct: 1 MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV 60 Query: 61 SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG 120 SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG Sbjct: 61 SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG 120 Query: 121 STAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDT 180 STAG EGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDT Sbjct: 121 STAGAEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDT 180 Query: 181 XXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA 240 VREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA Sbjct: 181 ACASSLSALHLAATAVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA 240 Query: 241 TGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKT 300 TGTVWGEGAGMVLV TNHNGKGKPILVPRVRAQEQVIRKT Sbjct: 241 TGTVWGEGAGMVLVERESRAQREGRRIYGRIAAIRTNHNGKGKPILVPRVRAQEQVIRKT 300 Query: 301 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQXXXX 360 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQ Sbjct: 301 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQAASG 360 Query: 361 XXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFG 420 QHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFG Sbjct: 361 ILALIKLLLAGQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFG 420 Query: 421 AGGANAHAIISMPAAGVGQ 439 AGGANAHAIISMPA GVGQ Sbjct: 421 AGGANAHAIISMPATGVGQ 439 >tr|B1MPF0|B1MPF0_MYCA9 Tax_Id=561007 SubName: Full=Putative polyketide synthase MbtC;[Mycobacterium abscessus] Length = 441 Score = 553 bits (1425), Expect = e-155 Identities = 258/424 (60%), Positives = 314/424 (74%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VISGMA+EAPGGID+PA+ W ALA+ REL+S FPRDRGWPVD+LLS+S+L+GWG++ Sbjct: 7 DPVVISGMAIEAPGGIDTPAAFWNALADGRELISAFPRDRGWPVDELLSLSNLDGWGRIS 66 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 D+GGF+ A+ FDP F+GI+ REA+ + PQQRVAMRVAWKALEN+G+NPG+ G+E GCF Sbjct: 67 DAGGFITDASAFDPTFYGITQREAVAMDPQQRVAMRVAWKALENTGLNPGAVDGSEAGCF 126 Query: 131 VGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXXX 190 +G+SP EYGP +A+SG R+ GQLG A RISH LGLIGPS+ VD+ Sbjct: 127 IGISPNEYGPPVGEVNAHSGMRVVGRGQLGAAGRISHGLGLIGPSVCVDSACASSLAALH 186 Query: 191 XXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGAG 250 VR DECEWA+AG VCVMGSPG FYEF+R++AL DGHCR+YSD A GT+WGE G Sbjct: 187 LAASAVRADECEWAIAGGVCVMGSPGGFYEFSRMHALDPDGHCRSYSDEANGTLWGEAVG 246 Query: 251 MVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPVE 310 MV++ TNHNG GKPILVPR RAQ +++ T+ +G+DP + Sbjct: 247 MVVLERESRARALGHRVYGRIMAVRTNHNGGGKPILVPRGRAQAKLVAATIAASGVDPAD 306 Query: 311 VGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQXXXXXXXXXXXXXX 370 VGM+EGHGT T AGDP+E++AL TYGA GS ALLGS KSNAGH+Q Sbjct: 307 VGMLEGHGTGTRAGDPLEILALQSTYGAGGSNALLGSAKSNAGHAQSAAGMVGLIKLLLS 366 Query: 371 XQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAHAII 430 QHG IPPTLFADNPT +DW +TG+RLATKLH WEPK G+RYG+VSSFGAGGANAHAII Sbjct: 367 GQHGHIPPTLFADNPTTKIDWSMTGIRLATKLHPWEPKDGIRYGSVSSFGAGGANAHAII 426 Query: 431 SMPA 434 +MPA Sbjct: 427 AMPA 430 >tr|Q5Z1T2|Q5Z1T2_NOCFA Tax_Id=37329 (nbtB)SubName: Full=Putative polyketide synthase;[Nocardia farcinica] Length = 436 Score = 470 bits (1209), Expect = e-130 Identities = 228/427 (53%), Positives = 284/427 (66%) Query: 7 AGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGW 66 + A DPIVI GM VEAPGG+++ W+ALA + EL+ PFPRDR WP+ ++ ++ EGW Sbjct: 2 SAADDPIVIVGMGVEAPGGVETLPQYWSALASATELIGPFPRDREWPLAEIFALGRREGW 61 Query: 67 GQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTE 126 V D+GGFL GAT FD FFGI+ REA+ + PQQRV MRVAW+ALE++G+NP G Sbjct: 62 SPVRDAGGFLTGATEFDAMFFGITPREAVAMDPQQRVGMRVAWRALEHAGLNPAGLDGAS 121 Query: 127 GGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXX 186 GC++G+S +EYGPRAS + YSG R A RISH+LGLIGPS+SVDT Sbjct: 122 VGCYMGVSMIEYGPRASAVNDYSGFRATGTALGAVAGRISHALGLIGPSVSVDTACASSL 181 Query: 187 XXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWG 246 +R EC+WALAG VCVMG+PGAFYEF++ NAL+ DGHCR Y+ +ATGT+WG Sbjct: 182 TAVHQAAAAIRAGECDWALAGGVCVMGTPGAFYEFSKNNALATDGHCRPYAADATGTLWG 241 Query: 247 EGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGI 306 EGAG+V++ NHNGKG P+ VP AQE+++R TL VAGI Sbjct: 242 EGAGVVVLERQSRALAQGHRIYGQLLGSRINHNGKGAPLAVPNATAQERLVRDTLAVAGI 301 Query: 307 DPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +P VG++EGHGT TP GDP+EL AL TYGA G+ LLGS+KSN GH+Q Sbjct: 302 EPELVGLVEGHGTGTPVGDPLELTALGATYGAPGANTLLGSVKSNVGHAQAASGMLGLIK 361 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 HG+I PTL+AD PT VDWD T LRLA + W+P GVRYGAVSSFG G NA Sbjct: 362 LLLCGLHGEIAPTLWADRPTAEVDWDATTLRLAAQAQPWKPIDGVRYGAVSSFGVAGTNA 421 Query: 427 HAIISMP 433 HAI++MP Sbjct: 422 HAIVAMP 428 >tr|D0L276|D0L276_GORB4 Tax_Id=526226 SubName: Full=Beta-ketoacyl synthase;[Gordonia bronchialis] Length = 454 Score = 414 bits (1064), Expect = e-113 Identities = 216/428 (50%), Positives = 274/428 (64%), Gaps = 8/428 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+V+ GMAVEAPGGID+ A W ALA+ R+L+SPFPRDRGW V++LLS+S GW V Sbjct: 17 DPVVVVGMAVEAPGGIDTLAGYWEALADGRDLISPFPRDRGWDVEELLSLSTDHGWAPVA 76 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 D+GGFLDGA FDP FFGIS REA+ + PQQRV +R AW A+EN+GINP S +G E G + Sbjct: 77 DAGGFLDGAGAFDPLFFGISPREAVAMDPQQRVVLRTAWHAVENAGINPASLSGREVGVY 136 Query: 131 VGMSPMEYGPRASVADAYSGHRIA--SLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S EYGPRA+ + YSG+R + +LG L G RIS L L GPS++VDT Sbjct: 137 VGGSINEYGPRAAEVNEYSGYRASGTALGALAG--RISRCLELTGPSLTVDTACASSLTA 194 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R+DE E ALAG VCVMGS AFYEF++ NAL+ G CR YS A GT+WGEG Sbjct: 195 LDLAVRSLRDDESELALAGGVCVMGSAAAFYEFSKNNALAGGGQCRPYSSFADGTLWGEG 254 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 AG+V++ NHNG G I +P AQ++++ + + +G+ Sbjct: 255 AGVVVLERRSRALANNRRIYGEIAATGVNHNGGGVGIALPSATAQQRLMARVRDRSGLPG 314 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 V+ +IEGHGT T GDP+EL AL YGA AG ++GS+KSN GH+Q Sbjct: 315 VD--LIEGHGTGTAVGDPLELTALSAVYGAGSAGEPTVIGSVKSNLGHAQAAAGMLGLIK 372 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 HGQI PT A++PT +DWD +GLRLA KL +W + G R+ AVSSFG G NA Sbjct: 373 VLLCGLHGQIAPTRHAESPTTEIDWDTSGLRLAAKLEDWPDRDGARHAAVSSFGIAGTNA 432 Query: 427 HAIISMPA 434 HAI++MPA Sbjct: 433 HAIVTMPA 440 >tr|A3Q280|A3Q280_MYCSJ Tax_Id=164757 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium sp.] Length = 443 Score = 395 bits (1014), Expect = e-108 Identities = 205/434 (47%), Positives = 264/434 (60%), Gaps = 6/434 (1%) Query: 4 NGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDL 63 N A DP+VI GMAVEAPGGID+P W L+E RE L PFP DRGW + +L + S Sbjct: 5 NRLAAEPDPVVIVGMAVEAPGGIDTPEDYWTLLSEQREALCPFPTDRGWSLRELFTGSRR 64 Query: 64 EGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 EG+ + D GGFL A+TFDP FFGIS REA+ + PQQRVA+R+AW+ALENSGINP A Sbjct: 65 EGFKPIHDLGGFLTSASTFDPEFFGISPREAVAMDPQQRVALRLAWRALENSGINPDDLA 124 Query: 124 GTEGGCFVGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTX 181 G + GC++G S +EYGP S +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 GHDVGCYLGASALEYGPELSEFSHHSGHLITGTSLGVVSG--RIAYTLDLAGPAVTVDTS 182 Query: 182 XXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNAT 241 +R +C+ AL G VCVMGSPG F EF+ +ALS+DGHCR YS +A+ Sbjct: 183 CSSALSAFHLAVQALRSGDCDLALTGGVCVMGSPGYFVEFSTQHALSDDGHCRPYSAHAS 242 Query: 242 GTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTL 301 GTVW EGAG+ ++ N +G+ + P RAQ ++ K + Sbjct: 243 GTVWAEGAGLFVLQRKSGAVRDGRDILAEVRASSINSDGRTVGLTAPSERAQSRLFGKAI 302 Query: 302 EVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG--AAGSEALLGSIKSNAGHSQXXX 359 AGI P +VGMIEGHGT T GD EL +L TYG A LLGS+KSN GH+Q Sbjct: 303 REAGISPEDVGMIEGHGTGTRLGDKTELRSLAATYGDTAPARGPLLGSVKSNIGHTQSAA 362 Query: 360 XXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSF 419 + IPPTL AD P++ +DWD +GLRLA KL W ++G R GAVS+F Sbjct: 363 GALGLAKVLVSAERATIPPTLHADEPSREIDWDTSGLRLANKLTPWPARNGERVGAVSAF 422 Query: 420 GAGGANAHAIISMP 433 G G N H ++++P Sbjct: 423 GMSGTNTHVVVAVP 436 >tr|A4T2D8|A4T2D8_MYCGI Tax_Id=350054 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium gilvum] Length = 435 Score = 394 bits (1012), Expect = e-107 Identities = 205/432 (47%), Positives = 270/432 (62%), Gaps = 6/432 (1%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 + DP+VI+GMA+EAPGGID+P + WA LAE RE+L PFP DRGW V DLL S EG+ + Sbjct: 4 SGDPVVIAGMALEAPGGIDTPDAYWAMLAEEREVLGPFPTDRGWAVRDLLDGSRREGFKR 63 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 + D GGFL GA FDP FFGIS REA+ + PQQRVA+RVAW+ALEN+GINP + AG E G Sbjct: 64 IHDRGGFLAGAAQFDPEFFGISPREAVAIDPQQRVALRVAWRALENAGINPDTLAGREVG 123 Query: 129 CFVGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXX 186 C+VG S + YG + A+SGH + +LG + G RI++ LGL GP++++D Sbjct: 124 CYVGASYLGYGGDLAEFTAHSGHLLTGTTLGAISG--RIAYVLGLGGPALTIDASCTGGL 181 Query: 187 XXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWG 246 +R +C+ AL G VCV+GSPG F EF+ +ALS+DGHCR YS +A+GTVW Sbjct: 182 AALHVAVSALRAGDCDVALTGGVCVLGSPGYFVEFSSQHALSDDGHCRPYSAHASGTVWA 241 Query: 247 EGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGI 306 EGA M ++ N +G+ K + P AQ ++ R+TL++AG+ Sbjct: 242 EGAAMFVLTRRSVAQREGYPVLAEILASGVNSDGRTKGMTAPSGDAQARLFRRTLDLAGV 301 Query: 307 DPVEVGMIEGHGTATPAGDPVELIALFKTYGAA--GSEALLGSIKSNAGHSQXXXXXXXX 364 P ++GMIEGHGT T GD EL +L TYGA GS +LGS+KSN GH+Q Sbjct: 302 RPDQIGMIEGHGTGTRLGDRTELHSLATTYGATRPGSGGVLGSVKSNIGHAQAAAGPLGL 361 Query: 365 XXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGA 424 +H IP +L D P++ +DW+ GL LATKL W G R AVS+FG GA Sbjct: 362 AKVLVAAEHAAIPRSLHTDQPSREIDWETQGLTLATKLTRWPAVDGRRLAAVSAFGMSGA 421 Query: 425 NAHAIISMPAAG 436 NAHAI+++P G Sbjct: 422 NAHAIVAVPDGG 433 >tr|Q1B6A9|Q1B6A9_MYCSS Tax_Id=164756 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium sp.] Length = 443 Score = 391 bits (1004), Expect = e-106 Identities = 203/434 (46%), Positives = 263/434 (60%), Gaps = 6/434 (1%) Query: 4 NGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDL 63 N A DP+VI GMAVEAPGGID+P W L+E RE L PFP DRGW + +L + S Sbjct: 5 NRLAAEPDPVVIVGMAVEAPGGIDTPEDYWTLLSEQREALCPFPTDRGWSLRELFTGSRR 64 Query: 64 EGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 EG+ + D GGFL A+TFDP FFG+S REA+ + PQQRVA+R+AW+ALENSGINP A Sbjct: 65 EGFKPIHDLGGFLTSASTFDPEFFGLSPREAVAMDPQQRVALRLAWRALENSGINPDDLA 124 Query: 124 GTEGGCFVGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTX 181 G + GC++G S +EYGP S +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 GHDVGCYLGASALEYGPELSEFSHHSGHLITGTSLGVVSG--RIAYTLDLAGPAVTVDTS 182 Query: 182 XXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNAT 241 +R +C+ AL G VCVMGSPG F EF+ +ALS+DGHCR YS +A+ Sbjct: 183 CSSALSAFHLAVQALRSGDCDLALTGGVCVMGSPGYFVEFSTQHALSDDGHCRPYSAHAS 242 Query: 242 GTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTL 301 GTVW EGAG+ ++ N +G+ + P RAQ ++ K + Sbjct: 243 GTVWAEGAGLFVLQRKSGAVRDGRDILAEVRASSINSDGRTVGLTAPSERAQSRLFGKAI 302 Query: 302 EVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG--AAGSEALLGSIKSNAGHSQXXX 359 AGI +VGMIEGHGT T GD EL +L TYG A LLGS+KSN GH+Q Sbjct: 303 REAGISSEDVGMIEGHGTGTRLGDKTELRSLAATYGDTAPARGPLLGSVKSNIGHTQSAA 362 Query: 360 XXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSF 419 + IPPTL AD P++ +DWD +GLRLA KL W ++G R GAVS+F Sbjct: 363 GALGLAKVLVSAERATIPPTLHADEPSREIDWDTSGLRLANKLTPWPARNGERVGAVSAF 422 Query: 420 GAGGANAHAIISMP 433 G G N H ++++P Sbjct: 423 GMSGTNTHVVVAVP 436 >tr|A1UIR7|A1UIR7_MYCSK Tax_Id=189918 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium sp.] Length = 443 Score = 391 bits (1004), Expect = e-106 Identities = 203/434 (46%), Positives = 263/434 (60%), Gaps = 6/434 (1%) Query: 4 NGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDL 63 N A DP+VI GMAVEAPGGID+P W L+E RE L PFP DRGW + +L + S Sbjct: 5 NRLAAEPDPVVIVGMAVEAPGGIDTPEDYWTLLSEQREALCPFPTDRGWSLRELFTGSRR 64 Query: 64 EGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 EG+ + D GGFL A+TFDP FFG+S REA+ + PQQRVA+R+AW+ALENSGINP A Sbjct: 65 EGFKPIHDLGGFLTSASTFDPEFFGLSPREAVAMDPQQRVALRLAWRALENSGINPDDLA 124 Query: 124 GTEGGCFVGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTX 181 G + GC++G S +EYGP S +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 GHDVGCYLGASALEYGPELSEFSHHSGHLITGTSLGVVSG--RIAYTLDLAGPAVTVDTS 182 Query: 182 XXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNAT 241 +R +C+ AL G VCVMGSPG F EF+ +ALS+DGHCR YS +A+ Sbjct: 183 CSSALSAFHLAVQALRSGDCDLALTGGVCVMGSPGYFVEFSTQHALSDDGHCRPYSAHAS 242 Query: 242 GTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTL 301 GTVW EGAG+ ++ N +G+ + P RAQ ++ K + Sbjct: 243 GTVWAEGAGLFVLQRKSGAVRDGRDILAEVRASSINSDGRTVGLTAPSERAQSRLFGKAI 302 Query: 302 EVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG--AAGSEALLGSIKSNAGHSQXXX 359 AGI +VGMIEGHGT T GD EL +L TYG A LLGS+KSN GH+Q Sbjct: 303 REAGISSEDVGMIEGHGTGTRLGDKTELRSLAATYGDTAPARGPLLGSVKSNIGHTQSAA 362 Query: 360 XXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSF 419 + IPPTL AD P++ +DWD +GLRLA KL W ++G R GAVS+F Sbjct: 363 GALGLAKVLVSAERATIPPTLHADEPSREIDWDTSGLRLANKLTPWPARNGERVGAVSAF 422 Query: 420 GAGGANAHAIISMP 433 G G N H ++++P Sbjct: 423 GMSGTNTHVVVAVP 436 >tr|A1TBS8|A1TBS8_MYCVP Tax_Id=350058 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium vanbaalenii] Length = 438 Score = 386 bits (991), Expect = e-105 Identities = 202/428 (47%), Positives = 261/428 (60%), Gaps = 6/428 (1%) Query: 10 ADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQV 69 ADP+VI GMAVEAPGG+++ W LAE RE LS FP DRGW + L S +G+ ++ Sbjct: 4 ADPVVIVGMAVEAPGGVENAHDYWTLLAEQRETLSSFPDDRGWSLRALFDGSRRDGFKRI 63 Query: 70 CDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGC 129 + GGFL GA +FDP FFGIS REA+ + PQQRVA+RV+W+ALE++ INP AG + GC Sbjct: 64 HNLGGFLTGAGSFDPEFFGISRREAVAMDPQQRVALRVSWRALESAQINPDDLAGHDVGC 123 Query: 130 FVGMSPMEYGPRASVADAYSGHRIA--SLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 +VG S M YGP +SGH I SLG + G RI+++LGL GP+I+VDT Sbjct: 124 YVGASDMRYGPAMDEFSHHSGHLITGTSLGVISG--RIAYTLGLAGPAITVDTSCSSALS 181 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R +C+ ALAG VCVMGSPG F EF++ +ALS+DGHCR YS +A+GTVW E Sbjct: 182 AFHVAVAGLRSGDCDLALAGGVCVMGSPGYFVEFSKQHALSDDGHCRPYSAHASGTVWAE 241 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 GAGM ++ N +G+ + P AQ ++ R+ L AG+D Sbjct: 242 GAGMFVLQRKSAAVRDRRRILGEVLASCVNSDGRSVGLTAPSQEAQIRLFRRALTTAGVD 301 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTY--GAAGSEALLGSIKSNAGHSQXXXXXXXXX 365 VGM+EGHGT T GD EL +L TY GAAG LLGS+KSN GHSQ Sbjct: 302 VDTVGMVEGHGTGTRLGDCTELNSLAATYGAGAAGRGPLLGSVKSNVGHSQAAAGALGLA 361 Query: 366 XXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGAN 425 QHG +P TL D P++ +DW+ TGLRLA KL W +G R GAVS+FG G N Sbjct: 362 KVLLAAQHGAVPATLHVDEPSREIDWENTGLRLAAKLTPWPAVNGARTGAVSAFGMSGTN 421 Query: 426 AHAIISMP 433 H ++++P Sbjct: 422 THVVVAVP 429 >tr|A0R0U7|A0R0U7_MYCS2 Tax_Id=246196 SubName: Full=Polyketide synthase;[Mycobacterium smegmatis] Length = 433 Score = 385 bits (989), Expect = e-105 Identities = 203/429 (47%), Positives = 259/429 (60%), Gaps = 6/429 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI GMA+EAPGG+ + W L E RE L FPRDRGW + L S +G+ + Sbjct: 6 DPVVIVGMALEAPGGVTTADDYWTLLTEEREALGRFPRDRGWDIGALFDGSRRDGFKPIN 65 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 D GGFL GA FDP FFGIS REA+ + PQQRVA+RVAW+ALENSGINP AG + GC+ Sbjct: 66 DLGGFLSGAGEFDPAFFGISPREAVAMDPQQRVALRVAWRALENSGINPDDLAGHDAGCY 125 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 +G S +EYGP S +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 126 IGASGLEYGPPLSEFSHHSGHLITGTSLGVIAG--RIAYTLDLAGPAVTVDTSCSSALTA 183 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ A+ GAVCVMGSPG F EF++ +ALS+DG CR YS +A+GTVW EG Sbjct: 184 LHTAVGALRAGDCDLAVTGAVCVMGSPGYFVEFSKQHALSDDGRCRPYSAHASGTVWAEG 243 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M ++ N +G+ + P AQE++ RK ++ AGI P Sbjct: 244 AAMFVLQRRSAAVRDGRRILAEIRATALNQDGRTTGLTAPSGAAQERLFRKAIDRAGIRP 303 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGAA--GSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGMIEGHGT T GD EL +L +TYGA G+ A+LGS+KSN GH+Q Sbjct: 304 EDVGMIEGHGTGTRLGDRTELRSLAQTYGATAPGAGAVLGSVKSNVGHAQAAAGGLGLAK 363 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 Q IP TL D P+ +DWD GLRLATKL W G R AVS+FG G NA Sbjct: 364 VLLAGQRAAIPATLHVDQPSGEIDWDAQGLRLATKLTPWPAVDGERIAAVSAFGMSGTNA 423 Query: 427 HAIISMPAA 435 HAI+++P A Sbjct: 424 HAIVAIPEA 432 >tr|A0QE92|A0QE92_MYCA1 Tax_Id=243243 SubName: Full=Erythronolide synthase, modules 1 and 2; EC=2.3.1.94;[Mycobacterium avium] Length = 442 Score = 381 bits (979), Expect = e-104 Identities = 203/436 (46%), Positives = 257/436 (58%), Gaps = 3/436 (0%) Query: 1 MSTNG-SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLS 59 MS NG A DP+VI GM VEAPGGI++ W LA RE L PFP DRGW V +LL+ Sbjct: 4 MSENGFDAAGIDPVVIVGMGVEAPGGIETAEDYWELLAHGREALGPFPTDRGWAVSELLA 63 Query: 60 VSDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINP 119 S G+ Q+ D GGFL GA TFDP FFGIS REA+V+ PQQRVA+RVAW+ALENSGINP Sbjct: 64 GSRRSGFKQIHDRGGFLSGAATFDPEFFGISPREAVVMDPQQRVALRVAWRALENSGINP 123 Query: 120 GSTAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVD 179 AG + GCFVG S YGP + +SGH +A + RI+++LGL GP+++VD Sbjct: 124 DDLAGEDVGCFVGASATGYGPEMARFSEHSGHLLAGTALSVISGRIAYTLGLTGPALTVD 183 Query: 180 TXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDN 239 + ++ +C+ ALAG V V+GSPG F EF++ +ALS+DGHCR YS Sbjct: 184 SSCASALVAFHVAVRALQNGDCDLALAGGVNVLGSPGFFVEFSKQHALSDDGHCRPYSAQ 243 Query: 240 ATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRK 299 A+GTVW EGA M ++ N +G+ + P AQ ++ R+ Sbjct: 244 ASGTVWAEGAAMFVLQRKSAALQAGRRVVAEVRATAINQDGRSAGLSAPSGDAQVRLFRR 303 Query: 300 TLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG--AAGSEALLGSIKSNAGHSQX 357 L +G+ P EVGMIEGHGT T GD EL +L +TYG G+ ALLGS+KSN GHS Sbjct: 304 ALGESGVKPAEVGMIEGHGTGTRLGDRTELRSLAQTYGDTEPGAGALLGSVKSNLGHSLA 363 Query: 358 XXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVS 417 +HG +PPTL A + +DW+ GLRLA L W G R A S Sbjct: 364 AAGALGLAKVLVSAEHGAVPPTLHATEASGEIDWEHQGLRLAQTLTPWPAIDGQRTAAAS 423 Query: 418 SFGAGGANAHAIISMP 433 +FG G NAH I+SMP Sbjct: 424 AFGIAGTNAHLIVSMP 439 >tr|Q73XY3|Q73XY3_MYCPA Tax_Id=1770 (mbtC)SubName: Full=MbtC;[Mycobacterium paratuberculosis] Length = 442 Score = 380 bits (975), Expect = e-103 Identities = 201/436 (46%), Positives = 257/436 (58%), Gaps = 3/436 (0%) Query: 1 MSTNG-SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLS 59 MS NG A DP+VI GM VEAPGGI++ W LA RE L PFP DRGW V +LL+ Sbjct: 4 MSENGFDAAGIDPVVIVGMGVEAPGGIETAEDYWELLAHGREALGPFPTDRGWAVSELLA 63 Query: 60 VSDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINP 119 S G+ Q+ D GGFL GA TFDP FFG+S REA+V+ PQQRVA+RVAW+ALENSGINP Sbjct: 64 GSRRSGFKQIHDRGGFLSGAATFDPEFFGVSPREAVVMDPQQRVALRVAWRALENSGINP 123 Query: 120 GSTAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVD 179 AG + GC+VG S YGP + +SGH +A + RI+++LGL GP+++VD Sbjct: 124 DDLAGEDVGCYVGASATGYGPEMARFSEHSGHLLAGTALSVISGRIAYTLGLTGPALTVD 183 Query: 180 TXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDN 239 + ++ +C+ ALAG V V+GSPG F EF++ +ALS+DGHCR YS Sbjct: 184 SSCASALVAFHVAVRALQNGDCDLALAGGVNVLGSPGFFVEFSKQHALSDDGHCRPYSAQ 243 Query: 240 ATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRK 299 A+GTVW EGA M ++ N +G+ + P AQ ++ R+ Sbjct: 244 ASGTVWAEGAAMFVLQRKSVALRAGRRVVAEVRATAINQDGRSAGLSAPSGDAQVRLFRR 303 Query: 300 TLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG--AAGSEALLGSIKSNAGHSQX 357 L +G+ P EVGMIEGHGT T GD EL +L +TYG G+ ALLGS+KSN GHS Sbjct: 304 ALGESGVKPAEVGMIEGHGTGTRLGDRTELRSLAQTYGDTEPGAGALLGSVKSNLGHSLA 363 Query: 358 XXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVS 417 +HG +PPTL A + +DW+ GLRLA L W G R A S Sbjct: 364 AAGALGLAKVLVSAEHGAVPPTLHATEASGEIDWEHQGLRLAQTLTPWPAIDGQRTAAAS 423 Query: 418 SFGAGGANAHAIISMP 433 +FG G NAH I+SMP Sbjct: 424 AFGIAGTNAHLIVSMP 439 >tr|Q7TYQ5|Q7TYQ5_MYCBO Tax_Id=1765 (mbtC)SubName: Full=POLYKETIDE SYNTHETASE MBTC (POLYKETIDE SYNTHASE);[Mycobacterium bovis] Length = 444 Score = 372 bits (954), Expect = e-101 Identities = 194/427 (45%), Positives = 253/427 (59%), Gaps = 6/427 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI G+A+EAPGG+++ W L+E RE L PFP DRGW + +L S G+ + Sbjct: 5 DPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIH 64 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GGFL ATTFDP FF IS REA + PQQRV +RVAW+ LENSGINP AG + GC+ Sbjct: 65 NLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCY 124 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S +EYGP + +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 VGASALEYGPALTEFSHHSGHLITGTSLGVISG--RIAYTLDLAGPALTVDTSCSSALAA 182 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ ALAG VCVMG+PG F EF++ +ALS+DGHCR YS +A+GT W EG Sbjct: 183 FHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEG 242 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M L+ N +G + P AQ +++R+ + A + P Sbjct: 243 AAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVP 302 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGM+EGHGTAT GD EL +L +YG AG LLGS+KSN GH+Q Sbjct: 303 ADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVK 362 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QH IPPTL D P++ +DW+ GLRLA KL W G R AVS+FG G N+ Sbjct: 363 VILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNS 422 Query: 427 HAIISMP 433 H I+SMP Sbjct: 423 HVIVSMP 429 >tr|P71718|P71718_MYCTU Tax_Id=1773 (mbtC)SubName: Full=POLYKETIDE SYNTHETASE MBTC (POLYKETIDE SYNTHASE);[Mycobacterium tuberculosis] Length = 444 Score = 372 bits (954), Expect = e-101 Identities = 194/427 (45%), Positives = 253/427 (59%), Gaps = 6/427 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI G+A+EAPGG+++ W L+E RE L PFP DRGW + +L S G+ + Sbjct: 5 DPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIH 64 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GGFL ATTFDP FF IS REA + PQQRV +RVAW+ LENSGINP AG + GC+ Sbjct: 65 NLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCY 124 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S +EYGP + +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 VGASALEYGPALTEFSHHSGHLITGTSLGVISG--RIAYTLDLAGPALTVDTSCSSALAA 182 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ ALAG VCVMG+PG F EF++ +ALS+DGHCR YS +A+GT W EG Sbjct: 183 FHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEG 242 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M L+ N +G + P AQ +++R+ + A + P Sbjct: 243 AAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVP 302 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGM+EGHGTAT GD EL +L +YG AG LLGS+KSN GH+Q Sbjct: 303 ADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVK 362 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QH IPPTL D P++ +DW+ GLRLA KL W G R AVS+FG G N+ Sbjct: 363 VILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNS 422 Query: 427 HAIISMP 433 H I+SMP Sbjct: 423 HVIVSMP 429 >tr|C6DNA2|C6DNA2_MYCTK Tax_Id=478434 SubName: Full=Polyketide synthetase mbtC;[Mycobacterium tuberculosis] Length = 444 Score = 372 bits (954), Expect = e-101 Identities = 194/427 (45%), Positives = 253/427 (59%), Gaps = 6/427 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI G+A+EAPGG+++ W L+E RE L PFP DRGW + +L S G+ + Sbjct: 5 DPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIH 64 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GGFL ATTFDP FF IS REA + PQQRV +RVAW+ LENSGINP AG + GC+ Sbjct: 65 NLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCY 124 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S +EYGP + +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 VGASALEYGPALTEFSHHSGHLITGTSLGVISG--RIAYTLDLAGPALTVDTSCSSALAA 182 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ ALAG VCVMG+PG F EF++ +ALS+DGHCR YS +A+GT W EG Sbjct: 183 FHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEG 242 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M L+ N +G + P AQ +++R+ + A + P Sbjct: 243 AAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVP 302 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGM+EGHGTAT GD EL +L +YG AG LLGS+KSN GH+Q Sbjct: 303 ADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVK 362 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QH IPPTL D P++ +DW+ GLRLA KL W G R AVS+FG G N+ Sbjct: 363 VILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNS 422 Query: 427 HAIISMP 433 H I+SMP Sbjct: 423 HVIVSMP 429 >tr|C1AQU5|C1AQU5_MYCBT Tax_Id=561275 (mbtC)SubName: Full=Polyketide synthetase;[Mycobacterium bovis] Length = 444 Score = 372 bits (954), Expect = e-101 Identities = 194/427 (45%), Positives = 253/427 (59%), Gaps = 6/427 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI G+A+EAPGG+++ W L+E RE L PFP DRGW + +L S G+ + Sbjct: 5 DPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIH 64 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GGFL ATTFDP FF IS REA + PQQRV +RVAW+ LENSGINP AG + GC+ Sbjct: 65 NLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCY 124 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S +EYGP + +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 VGASALEYGPALTEFSHHSGHLITGTSLGVISG--RIAYTLDLAGPALTVDTSCSSALAA 182 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ ALAG VCVMG+PG F EF++ +ALS+DGHCR YS +A+GT W EG Sbjct: 183 FHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEG 242 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M L+ N +G + P AQ +++R+ + A + P Sbjct: 243 AAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVP 302 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGM+EGHGTAT GD EL +L +YG AG LLGS+KSN GH+Q Sbjct: 303 ADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVK 362 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QH IPPTL D P++ +DW+ GLRLA KL W G R AVS+FG G N+ Sbjct: 363 VILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNS 422 Query: 427 HAIISMP 433 H I+SMP Sbjct: 423 HVIVSMP 429 >tr|A5U575|A5U575_MYCTA Tax_Id=419947 (mbtC)SubName: Full=Polyketide synthetase MbtC;[Mycobacterium tuberculosis] Length = 444 Score = 372 bits (954), Expect = e-101 Identities = 194/427 (45%), Positives = 253/427 (59%), Gaps = 6/427 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI G+A+EAPGG+++ W L+E RE L PFP DRGW + +L S G+ + Sbjct: 5 DPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIH 64 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GGFL ATTFDP FF IS REA + PQQRV +RVAW+ LENSGINP AG + GC+ Sbjct: 65 NLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCY 124 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S +EYGP + +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 VGASALEYGPALTEFSHHSGHLITGTSLGVISG--RIAYTLDLAGPALTVDTSCSSALAA 182 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ ALAG VCVMG+PG F EF++ +ALS+DGHCR YS +A+GT W EG Sbjct: 183 FHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEG 242 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M L+ N +G + P AQ +++R+ + A + P Sbjct: 243 AAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVP 302 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGM+EGHGTAT GD EL +L +YG AG LLGS+KSN GH+Q Sbjct: 303 ADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVK 362 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QH IPPTL D P++ +DW+ GLRLA KL W G R AVS+FG G N+ Sbjct: 363 VILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNS 422 Query: 427 HAIISMP 433 H I+SMP Sbjct: 423 HVIVSMP 429 >tr|A1KL72|A1KL72_MYCBP Tax_Id=410289 (mbtC)SubName: Full=Polyketide synthetase mbtC;[Mycobacterium bovis] Length = 444 Score = 372 bits (954), Expect = e-101 Identities = 194/427 (45%), Positives = 253/427 (59%), Gaps = 6/427 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI G+A+EAPGG+++ W L+E RE L PFP DRGW + +L S G+ + Sbjct: 5 DPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIH 64 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GGFL ATTFDP FF IS REA + PQQRV +RVAW+ LENSGINP AG + GC+ Sbjct: 65 NLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCY 124 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S +EYGP + +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 VGASALEYGPALTEFSHHSGHLITGTSLGVISG--RIAYTLDLAGPALTVDTSCSSALAA 182 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ ALAG VCVMG+PG F EF++ +ALS+DGHCR YS +A+GT W EG Sbjct: 183 FHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEG 242 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M L+ N +G + P AQ +++R+ + A + P Sbjct: 243 AAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVP 302 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGM+EGHGTAT GD EL +L +YG AG LLGS+KSN GH+Q Sbjct: 303 ADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVK 362 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QH IPPTL D P++ +DW+ GLRLA KL W G R AVS+FG G N+ Sbjct: 363 VILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNS 422 Query: 427 HAIISMP 433 H I+SMP Sbjct: 423 HVIVSMP 429 >tr|Q7D789|Q7D789_MYCTU Tax_Id=1773 SubName: Full=Polyketide synthase;[Mycobacterium tuberculosis] Length = 446 Score = 372 bits (954), Expect = e-101 Identities = 194/427 (45%), Positives = 253/427 (59%), Gaps = 6/427 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI G+A+EAPGG+++ W L+E RE L PFP DRGW + +L S G+ + Sbjct: 7 DPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIH 66 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GGFL ATTFDP FF IS REA + PQQRV +RVAW+ LENSGINP AG + GC+ Sbjct: 67 NLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCY 126 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S +EYGP + +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 127 VGASALEYGPALTEFSHHSGHLITGTSLGVISG--RIAYTLDLAGPALTVDTSCSSALAA 184 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ ALAG VCVMG+PG F EF++ +ALS+DGHCR YS +A+GT W EG Sbjct: 185 FHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEG 244 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M L+ N +G + P AQ +++R+ + A + P Sbjct: 245 AAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVP 304 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGM+EGHGTAT GD EL +L +YG AG LLGS+KSN GH+Q Sbjct: 305 ADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVK 364 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QH IPPTL D P++ +DW+ GLRLA KL W G R AVS+FG G N+ Sbjct: 365 VILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNS 424 Query: 427 HAIISMP 433 H I+SMP Sbjct: 425 HVIVSMP 431 >tr|A5WPZ7|A5WPZ7_MYCTF Tax_Id=336982 SubName: Full=Polyketide synthetase mbtC;[Mycobacterium tuberculosis] Length = 444 Score = 372 bits (954), Expect = e-101 Identities = 194/427 (45%), Positives = 253/427 (59%), Gaps = 6/427 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI G+A+EAPGG+++ W L+E RE L PFP DRGW + +L S G+ + Sbjct: 5 DPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIH 64 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GGFL ATTFDP FF IS REA + PQQRV +RVAW+ LENSGINP AG + GC+ Sbjct: 65 NLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCY 124 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S +EYGP + +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 VGASALEYGPALTEFSHHSGHLITGTSLGVISG--RIAYTLDLAGPALTVDTSCSSALAA 182 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ ALAG VCVMG+PG F EF++ +ALS+DGHCR YS +A+GT W EG Sbjct: 183 FHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEG 242 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M L+ N +G + P AQ +++R+ + A + P Sbjct: 243 AAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVP 302 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGM+EGHGTAT GD EL +L +YG AG LLGS+KSN GH+Q Sbjct: 303 ADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVK 362 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QH IPPTL D P++ +DW+ GLRLA KL W G R AVS+FG G N+ Sbjct: 363 VILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNS 422 Query: 427 HAIISMP 433 H I+SMP Sbjct: 423 HVIVSMP 429 >tr|A4KJD2|A4KJD2_MYCTU Tax_Id=395095 SubName: Full=Polyketide synthetase mbtC;[Mycobacterium tuberculosis str. Haarlem] Length = 444 Score = 372 bits (954), Expect = e-101 Identities = 194/427 (45%), Positives = 253/427 (59%), Gaps = 6/427 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI G+A+EAPGG+++ W L+E RE L PFP DRGW + +L S G+ + Sbjct: 5 DPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIH 64 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GGFL ATTFDP FF IS REA + PQQRV +RVAW+ LENSGINP AG + GC+ Sbjct: 65 NLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCY 124 Query: 131 VGMSPMEYGPRASVADAYSGHRI--ASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG S +EYGP + +SGH I SLG + G RI+++L L GP+++VDT Sbjct: 125 VGASALEYGPALTEFSHHSGHLITGTSLGVISG--RIAYTLDLAGPALTVDTSCSSALAA 182 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +C+ ALAG VCVMG+PG F EF++ +ALS+DGHCR YS +A+GT W EG Sbjct: 183 FHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEG 242 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 A M L+ N +G + P AQ +++R+ + A + P Sbjct: 243 AAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVP 302 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +VGM+EGHGTAT GD EL +L +YG AG LLGS+KSN GH+Q Sbjct: 303 ADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVK 362 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QH IPPTL D P++ +DW+ GLRLA KL W G R AVS+FG G N+ Sbjct: 363 VILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNS 422 Query: 427 HAIISMP 433 H I+SMP Sbjct: 423 HVIVSMP 429 >tr|C2AVC8|C2AVC8_TSUPA Tax_Id=521096 SubName: Full=Beta-ketoacyl synthase;[Tsukamurella paurometabola DSM 20162] Length = 433 Score = 362 bits (930), Expect = 4e-98 Identities = 193/424 (45%), Positives = 248/424 (58%), Gaps = 2/424 (0%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 AAD IVI+G+ +EAPGG+++ LW AL +L FPRDRGW + ++ ++ + G+ + Sbjct: 6 AADRIVITGIGLEAPGGVETVEQLWDALETGEDLTGHFPRDRGWDLGEIFALHERRGYQR 65 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 V D GGFLD A FDP FFG+S REAI + PQQRVA+RVA +AL ++GI P S GT G Sbjct: 66 VPDRGGFLDAAAEFDPAFFGLSPREAIAMDPQQRVALRVAHRALAHAGIAPRSLHGTRTG 125 Query: 129 CFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 C++G S MEYGP + + Y+GHR+A A RI+H LG +GP+++VD Sbjct: 126 CYLGASAMEYGPSPAEVNEYAGHRVAGAALGAVAGRIAHHLGTVGPAMTVDAACASSLTA 185 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +CE AL G VCVMGSP AFYEF++ +AL+ DG AY A GTVWGEG Sbjct: 186 LHVAIAGLRSGDCELALVGGVCVMGSPAAFYEFSKNHALAPDGVLHAYGAGAAGTVWGEG 245 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 AG+++V +HNG G PI+VP AQ ++ TL VAG+DP Sbjct: 246 AGVLVVETAAHAAAAGRPVLAEVLATRVSHNGGGGPIVVPSEAAQTALVADTLAVAGVDP 305 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQXXXXXXXXXXXX 368 +VGM+EGHGT TP GDP EL AL YG AG LGSIKS GH+Q Sbjct: 306 DDVGMVEGHGTGTPLGDPAELAALATAYGRAG-VCWLGSIKSATGHTQAAAGVLGLAKAV 364 Query: 369 XXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEP-KHGVRYGAVSSFGAGGANAH 427 + G + TL AD PT DW L L + P G R AVSSFG G+NAH Sbjct: 365 LCARAGVVAATLHADPPTPRHDWGAGALALPHAAQPFRPAADGRRIAAVSSFGVAGSNAH 424 Query: 428 AIIS 431 A+I+ Sbjct: 425 ALIT 428 >tr|O54593|O54593_AMYMD Tax_Id=33910 (rifE)SubName: Full=RifE; SubName: Full=Rifamycin polyketide synthase, type 1;[Amycolatopsis mediterranei] Length = 3413 Score = 317 bits (812), Expect = 2e-84 Identities = 168/433 (38%), Positives = 230/433 (53%), Gaps = 4/433 (0%) Query: 1 MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV 60 ++T +A A +PI I GMA PGG+ P LW + + E LSPFP DRGW +++L Sbjct: 1692 VATAAAADAGEPIAIVGMACRLPGGVTDPEGLWRLVRDGLEGLSPFPEDRGWDLENLFDD 1751 Query: 61 SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG 120 GGFLDGA FD GFFGIS REA+ + PQQR+ + AW+ALE +G++PG Sbjct: 1752 DPDRSGTTYTSRGGFLDGAGLFDAGFFGISPREALAMDPQQRLLLEAAWEALEGTGVDPG 1811 Query: 121 STAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDT 180 S G + G F G+S YG A A+ +G+ + + R+S+ G GP++++DT Sbjct: 1812 SLKGADVGVFAGVSNQGYGMGADPAE-LAGYASTAGASSVVSGRVSYVFGFEGPAVTIDT 1870 Query: 181 XXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA 240 +R+ EC ALAG V VMG+PG F EFA+ L+ DG C+AY++ A Sbjct: 1871 ACSSSLVAMHLAGQALRQGECSMALAGGVTVMGTPGTFVEFAKQRGLAGDGRCKAYAEGA 1930 Query: 241 TGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKT 300 GT W EG G+V++ N +G + P +Q++VIR+ Sbjct: 1931 DGTGWAEGVGVVVLERLSVARERGHRVLAVLRGSAVNSDGASNGLTAPNGPSQQRVIRRA 1990 Query: 301 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGA---AGSEALLGSIKSNAGHSQX 357 L AG++P +V ++EGHGT T GDP+E AL TYG + LGS+KSN GH+Q Sbjct: 1991 LAGAGLEPSDVDIVEGHGTGTALGDPIEAQALLATYGKDRDPETPLWLGSVKSNFGHTQS 2050 Query: 358 XXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVS 417 +HG +PPTL D PT VDW + + T+ EW R VS Sbjct: 2051 AAGVAGVIKMVQALRHGVMPPTLHVDRPTSQVDWSAGAVEVLTEAREWPRNGRPRRAGVS 2110 Query: 418 SFGAGGANAHAII 430 SFG G NAH II Sbjct: 2111 SFGISGTNAHLII 2123 Score = 286 bits (733), Expect = 3e-75 Identities = 165/440 (37%), Positives = 223/440 (50%), Gaps = 8/440 (1%) Query: 5 GSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLE 64 G+ A +P+ + GMA PGG+ SP LW +A + LS FP DRGW +D L Sbjct: 25 GARHADEPLAVVGMACRFPGGVSSPEDLWQLVAGGVDALSDFPDDRGWELDGLFDPDPDH 84 Query: 65 GWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAG 124 GGFL GA FD G FGIS REA+V+ PQQRV + +W+ALE++G++P S G Sbjct: 85 PGTSYTSQGGFLRGAGLFDAGLFGISPREALVMDPQQRVLLETSWEALEDAGVDPLSLKG 144 Query: 125 TEGGCFVGMSPMEYGPRASVAD--AYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXX 182 ++ G F G+ YG A D A++G AS G R+S+ GL GP++++DT Sbjct: 145 SDVGVFSGVFTQGYGAGAITPDLEAFAGIGAASSVASG---RVSYVFGLEGPAVTIDTAC 201 Query: 183 XXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATG 242 +R EC ALAG VM +PG F F+R L+ DG +A+S A G Sbjct: 202 SSSLVAIHLAAQALRAGECSMALAGGATVMPTPGTFVAFSRQRVLAADGRSKAFSSTADG 261 Query: 243 TVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLE 302 T W EGAG++++ N +G + P +Q++VIRK L Sbjct: 262 TGWAEGAGVLVLERLSVAQERGHRILAVLRGSAVNQDGASNGLTAPNGPSQQRVIRKALA 321 Query: 303 VAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXX 361 AG+ +V ++E HGT T GDP+E AL TYG L LGS+KSN GH+Q Sbjct: 322 GAGLVASDVDVVEAHGTGTALGDPIEAQALLATYGQGRERPLWLGSVKSNFGHTQAAAGV 381 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +HG +PPTL PT VDW + L T+ EW R VS+FG Sbjct: 382 AGVIKMVQALRHGAMPPTLHVAEPTPEVDWSAGAVELLTEPREWPAGDRPRRAGVSAFGI 441 Query: 422 GGANAHAII--SMPAAGVGQ 439 G NAH I+ + PA V + Sbjct: 442 SGTNAHLILEEAPPADAVAE 461 >tr|B4VAJ6|B4VAJ6_9ACTO Tax_Id=465541 SubName: Full=Polyketide synthase subunit; Flags: Fragment;[Streptomyces sp. Mg1] Length = 3605 Score = 310 bits (794), Expect = 2e-82 Identities = 169/423 (39%), Positives = 219/423 (51%), Gaps = 3/423 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GM PGG+ SP LW +A + +SPFP DRGW V L Sbjct: 1016 EPIAIVGMGCRLPGGVSSPEGLWDLVASGVDAVSPFPTDRGWDVAGLFDPEPGVPGRTYV 1075 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL GA FD GFFGIS REA+ + PQQR+ + +W+ALE +GI+P S G+ G + Sbjct: 1076 REGGFLHGAGEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGIDPHSLRGSRTGVY 1135 Query: 131 VGMSPMEYGPRA-SVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 G+ EYGPR AD Y G+ + + RIS+ LGL GP+++VDT Sbjct: 1136 AGVMAQEYGPRLHESADGYEGYLLTGSSSSVASGRISYVLGLEGPAVTVDTACSSSLVAL 1195 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC+ ALAG V VM PG F EF+R L+ DG C+A+SD+A GT W EGA Sbjct: 1196 HLAVRALRSGECDLALAGGVTVMAEPGMFVEFSRQRGLAADGRCKAFSDSADGTGWAEGA 1255 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G++LV N +G + P RAQ ++IR+ L A + Sbjct: 1256 GVLLVERLSDAVRHGHRVLAVVRGSAVNQDGASNGLTAPSGRAQSRLIRRALADARLGVG 1315 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXXX 367 +V ++E HGT T GDP+E AL TYG AG LGS+KSN GH+Q Sbjct: 1316 DVDVVEAHGTGTRLGDPIEAQALLATYGQRDAGRPLRLGSLKSNVGHTQAAAGVAGVIKM 1375 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 +HG +P TL D PT VDW + L T+ W VR VSSFG G NAH Sbjct: 1376 VMAMRHGVLPKTLHVDEPTAEVDWSAGTVALLTEQVPWPRSERVRRAGVSSFGVSGTNAH 1435 Query: 428 AII 430 ++ Sbjct: 1436 VVL 1438 Score = 287 bits (735), Expect = 2e-75 Identities = 160/423 (37%), Positives = 211/423 (49%), Gaps = 3/423 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GMA PG SP LW L + R+ + P P DRGW V L Sbjct: 2511 EPIAIVGMACRYPGEAHSPEELWKLLMDERDAIGPMPTDRGWDVAGLFDPEPGVPGRTYV 2570 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FD GFFGIS REA+ + PQQR+ + +W+ALE +GI+P S G+ G + Sbjct: 2571 REGGFLYEAGEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGIDPNSLRGSRTGVY 2630 Query: 131 VGMSPMEYGPRASVADA-YSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 GM EY R A A + GH + + RIS+ LGL GP+++VDT Sbjct: 2631 AGMFHQEYAARLHEAPAEFEGHLLTGTSGSVASGRISYVLGLEGPAVTVDTACSSSLVAL 2690 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC+ ALAG V VM PG F EF+R L+ DG C+A+SD+A GT W EG Sbjct: 2691 HLAVRALRSGECDLALAGGVTVMAEPGVFVEFSRQRGLAADGRCKAFSDSADGTGWAEGV 2750 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G++ V N +G + P +Q++VIR+ L A + Sbjct: 2751 GVLAVERLSDAVRHGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLGVG 2810 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXXX 367 +V ++E HGT T GDP+E AL TYG AG LGS+KSN GH+Q Sbjct: 2811 DVDVVEAHGTGTRLGDPIEAQALLATYGQRDAGRPLWLGSLKSNVGHTQAAAGVAGVIKM 2870 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 + G +P TL D P+ VDW + L T+ W VR VS+FG G NAH Sbjct: 2871 VMAMRDGVLPKTLHVDEPSAEVDWSAGAVSLLTEQEPWPRGERVRRAGVSAFGVSGTNAH 2930 Query: 428 AII 430 ++ Sbjct: 2931 VVL 2933 Score = 203 bits (516), Expect = 4e-50 Identities = 122/366 (33%), Positives = 176/366 (48%), Gaps = 9/366 (2%) Query: 74 GFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCFVGM 133 G L+GA FD FFG+S R+A PQQR+ + + W ALE++GI PGS AGT+ G FVG+ Sbjct: 63 GSLEGAADFDAAFFGMSPRQAAAADPQQRLMLELGWTALEDAGIVPGSLAGTDTGVFVGI 122 Query: 134 SPMEYGPRASVADA-YSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXXXXX 192 + +Y ++ SGH L + A R+S+ LGL GPS++VD+ Sbjct: 123 AADDYAALLHRSETPVSGHTATGLSRGMAANRLSYLLGLRGPSLAVDSAQSSSLVAVHLA 182 Query: 193 XXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGAGMV 252 +R E + A+ G V ++ + + + ALS DG C + A G V GEG V Sbjct: 183 CESLRRGESDLAIVGGVSLILAENSTAGMELMGALSPDGRCYTFDARANGYVRGEGGACV 242 Query: 253 LVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPVEVG 312 ++ N++G G + P AQE V+R E +G+ P +V Sbjct: 243 VLKPLDRALADGDRVHCVIRGSAVNNDGGGSTLTTPHREAQEAVLRAAYERSGVGPDQVS 302 Query: 313 MIEGHGTATPAGDPVELIALFKTYGAAGSEAL---LGSIKSNAGHSQXXXXXXXXXXXXX 369 +E HGT TPAGDP+E AL G A + +GS K+N GH + Sbjct: 303 YVELHGTGTPAGDPIEAAALGAVLGTARGRSTPLSVGSAKTNVGHLEAAAGLVGFVKAAL 362 Query: 370 XXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEW-----EPKHGVRYGAVSSFGAGGA 424 + G +PP+L P + D LR+ T+L W + +R VSSFG GG Sbjct: 363 CVREGVVPPSLNHATPNPAIPMDRLNLRVPTRLGTWPQPDEQATGRLRLAGVSSFGMGGT 422 Query: 425 NAHAII 430 NAH ++ Sbjct: 423 NAHVVL 428 >tr|B1W485|B1W485_STRGG Tax_Id=455632 (pks1-1)SubName: Full=Putative type-I PKS;[Streptomyces griseus subsp. griseus] Length = 5136 Score = 309 bits (792), Expect = 4e-82 Identities = 175/458 (38%), Positives = 232/458 (50%), Gaps = 21/458 (4%) Query: 2 STNGSAGAA------DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVD 55 S G GAA +PI I GMA PGG+ SP LW +A+ + +SPFP DRGW +D Sbjct: 1761 SAPGGPGAARASAVDEPIAIVGMACRLPGGVGSPEELWQLVADGVDAVSPFPTDRGWDMD 1820 Query: 56 DLLSVSDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENS 115 LL +D G GGFL A FD GFFGIS REA+ + PQQR+ + +W+ALE + Sbjct: 1821 ALLGATDGTGGTSYVREGGFLYDAADFDAGFFGISPREALAMDPQQRLLLETSWEALERA 1880 Query: 116 GINPGSTAGTEGGCFVGMSPMEYGPRAS-VADAYSGHRIASLGQLGGAARISHSLGLIGP 174 GI+P S GT G F G+ +Y R V + G+ + R++++LGL GP Sbjct: 1881 GIDPTSLNGTRTGVFTGVMYHDYASRLDRVPEEVGGYLATGTSGSVASGRVAYTLGLEGP 1940 Query: 175 SISVDTXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCR 234 +++VDT +R+ EC ALAG V V+ SP F EF+R L+ DG C+ Sbjct: 1941 AVTVDTACSSSLVALHLAAQALRQGECTMALAGGVTVLSSPSVFSEFSRQQGLATDGRCK 2000 Query: 235 AYSDNATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQE 294 +++D A GT W EG G++LV N +G + P AQ+ Sbjct: 2001 SFADAADGTGWAEGVGVLLVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQ 2060 Query: 295 QVIRKTLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAA---GSEALLGSIKSN 351 +VIR+ LE A + P +V +E HGT T GDP+E AL TYG G+ LLGS+KSN Sbjct: 2061 RVIRQALESARLSPTDVDAVEAHGTGTRLGDPIEAQALLATYGQGREEGAALLLGSLKSN 2120 Query: 352 AGHSQXXXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGV 411 GH+Q +HG +P TL D P+ VDW + L T+ EW Sbjct: 2121 IGHAQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSSHVDWSAGDVSLLTESREWPETGRP 2180 Query: 412 RYGAVSSFGAGGANAHAII-----------SMPAAGVG 438 R VSSFG G NAH I+ S PA G G Sbjct: 2181 RRAGVSSFGVSGTNAHVILEAVEHTDAPAHSTPAVGGG 2218 Score = 285 bits (729), Expect = 8e-75 Identities = 159/425 (37%), Positives = 211/425 (49%), Gaps = 5/425 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GMA PGGI SP LW +A+ E +S P DRGW +D L L Sbjct: 38 EPIAIVGMACRFPGGIGSPEDLWRMVADGAEGISELPTDRGWDLDALFDADPLRVGTSYI 97 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL GA FD GFFGIS REA+ + PQQR+ + AW+ +E +GI P + G G F Sbjct: 98 RGGGFLHGAAEFDAGFFGISPREALAMDPQQRLLLETAWETVERAGIVPAALRGENVGVF 157 Query: 131 VGMSPMEYGPRAS--VADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG P +Y PR A+ G+ + R++++LGL GP+++VDT Sbjct: 158 VGAVPQDYAPRHGDPAAEDVEGYLAVGNTTSVMSGRVAYTLGLRGPAVTVDTACSSSLVA 217 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R+ EC ALAG V VM +P + +R L+ DG C+A+++ A G EG Sbjct: 218 LHLAVQALRQGECTMALAGGVTVMAAPNWIVDLSRQQGLAPDGRCKAFAEGADGFGPAEG 277 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 G++LV N +G + P AQE VI + L AG+ P Sbjct: 278 VGLLLVERLSDALRNGHRVLAVVRGSAVNQDGASNGLTAPNDEAQEDVIVRALANAGVSP 337 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGAA---GSEALLGSIKSNAGHSQXXXXXXXXX 365 +V +E HGT T GDP+E AL TYG G+ LLGS+KSN GH+Q Sbjct: 338 RDVDAVEAHGTGTRLGDPIEAQALLATYGQGREEGAALLLGSLKSNIGHAQAAAGVAGVI 397 Query: 366 XXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGAN 425 +HG +P TL D P+ VDW + L T+ EW R VSSFG G N Sbjct: 398 KMVMAMRHGVLPRTLHVDEPSSHVDWSAGDVSLLTESREWPETGRPRRAGVSSFGISGTN 457 Query: 426 AHAII 430 AH I+ Sbjct: 458 AHVIL 462 Score = 282 bits (721), Expect = 7e-74 Identities = 154/434 (35%), Positives = 215/434 (49%), Gaps = 8/434 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +P+ I GMA PGG+ +P LW L + + ++ FP +RGW +D L Sbjct: 3317 EPVAIVGMACRLPGGVTTPEELWQLLRDGGDAITGFPENRGWDLDGLYDPDPATPGKTYA 3376 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FD GFFGIS REA+ + PQQR+ + +W+A+E++GI+P GT G F Sbjct: 3377 RDGGFLHDAAEFDAGFFGISPREALAMDPQQRLLLETSWEAIEHAGIDPTVLKGTRTGTF 3436 Query: 131 VGMSPMEYGPRASVADA---YSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 +G +P +Y RA++ A Y GH + + RI+++ GL GP+++VDT Sbjct: 3437 IGANPSDY--RAAMGQAPVGYEGHLVTGGHNSVVSGRIAYTFGLEGPAVTVDTACSSSLT 3494 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 V++ EC+ ALAG V +M +P F F+R LS DG CR +S +A G E Sbjct: 3495 ALHLAAQAVKQGECDMALAGGVAIMSTPEGFIGFSRQRGLSHDGRCRTFSSDAEGIGLSE 3554 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 G G++L+ TN +G + P +Q++VIR+ L AG+ Sbjct: 3555 GVGVILLERLSDAHRNGHPVLAVIRGSATNQDGASNGLSAPNGPSQQRVIRQALANAGLT 3614 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXXXXX 364 EV +E HGT T GDP+E AL TYG G LGS+KSN GH Q Sbjct: 3615 TAEVDAVEAHGTGTTLGDPIEAQALLATYGQDRTDGHPLYLGSLKSNIGHPQAAAGIAGV 3674 Query: 365 XXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGA 424 QHG +P TL + P+ VDW + L + EW R AVS FG G Sbjct: 3675 VKTVLALQHGVLPRTLHVEEPSPEVDWASGAVELLVREREWPRTGRPRRAAVSGFGISGT 3734 Query: 425 NAHAIISMPAAGVG 438 NAH ++ G Sbjct: 3735 NAHVVLEQAPVSSG 3748 >tr|Q8KPW5|Q8KPW5_9ACTO Tax_Id=201500 (gerSI)SubName: Full=Putative type I polyketide synthase;[Streptomyces sp. KCTC 0041BP] Length = 4387 Score = 309 bits (791), Expect = 5e-82 Identities = 168/423 (39%), Positives = 219/423 (51%), Gaps = 3/423 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GM PGG+ SP LW +A + +SPFP DRGW V L Sbjct: 1008 EPIAIVGMGCRLPGGVSSPEGLWDLVASGVDAVSPFPTDRGWDVAGLFDPEPGVPGRTYV 1067 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL GA FD GFFGIS REA+ + PQQR+ + +W+ALE +GI+P S G+ G + Sbjct: 1068 REGGFLHGAGEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGIDPHSLRGSRTGVY 1127 Query: 131 VGMSPMEYGPRA-SVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 G+ EYGPR AD Y G+ + + RIS+ LGL GP+++VDT Sbjct: 1128 AGVMAQEYGPRLHESADGYEGYLLTGSSGSVASGRISYVLGLEGPAVTVDTACSSSLVAL 1187 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC+ ALAG V VM PG F EF+R L+ DG C+A+SD+A GT W EGA Sbjct: 1188 HLAVRALRSGECDLALAGGVTVMAEPGMFVEFSRQRGLAADGRCKAFSDSADGTGWAEGA 1247 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G++LV N +G + P RAQ ++IR+ L A + Sbjct: 1248 GVLLVERLSDAVRHGHQVLAVVRGSAVNQDGASNGLTAPSGRAQSRLIRRALADARLGVG 1307 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXXX 367 +V ++E HGT T GDP+E AL TYG AG LGS+KSN GH+Q Sbjct: 1308 DVDVVEAHGTGTRLGDPIEAQALLATYGQRDAGRPLRLGSLKSNVGHTQAAAGVAGVIKM 1367 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 +HG +P TL D P+ VDW + L T+ W VR VSSFG G NAH Sbjct: 1368 VMAMRHGVLPKTLHVDEPSAEVDWSAGAVSLLTEQEPWPRGERVRRAGVSSFGVSGTNAH 1427 Query: 428 AII 430 ++ Sbjct: 1428 VVL 1430 Score = 291 bits (746), Expect = 9e-77 Identities = 161/423 (38%), Positives = 213/423 (50%), Gaps = 3/423 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GMA PG SP LW L + R+++ P P DRGW V L Sbjct: 2503 EPIAIVGMACRYPGEAHSPEELWKLLMDERDVIGPMPTDRGWDVAGLFDPEPGVPGRTYV 2562 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL GA FD GFFGIS REA+ + PQQR+ + +W+ALE +GI+P S G+ G + Sbjct: 2563 REGGFLHGAGEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGIDPHSLRGSRTGVY 2622 Query: 131 VGMSPMEYGPRASVADA-YSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 GM EY R A A + GH + + RIS+ LGL GP+++VDT Sbjct: 2623 AGMFHQEYAARLHEAPAEFEGHLLTGTSGSVASGRISYVLGLEGPAVTVDTACSSSLVAL 2682 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC+ ALAG V VM PG F EF+R L+ DG C+A+SD+A GT W EG Sbjct: 2683 HLAVRALRSGECDLALAGGVTVMAEPGVFVEFSRQRGLAADGRCKAFSDSADGTGWAEGV 2742 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G++ V N +G + P +Q++VIR+ L A + Sbjct: 2743 GVLAVERLSDAVRHGRRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLGVG 2802 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYG--AAGSEALLGSIKSNAGHSQXXXXXXXXXXX 367 +V ++E HGT T GDP+E AL TYG AG LGS+KSN GH+Q Sbjct: 2803 DVDVVEAHGTGTRLGDPIEAQALLATYGQRGAGRPLWLGSLKSNVGHTQAAAGVAGVIKM 2862 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 + G +P TL D P+ VDW + L T+ W VR VS+FG G NAH Sbjct: 2863 VMAMRDGVLPKTLHVDEPSAEVDWSAGAVSLLTEQEPWPRGERVRRAGVSAFGVSGTNAH 2922 Query: 428 AII 430 ++ Sbjct: 2923 VVL 2925 Score = 206 bits (524), Expect = 5e-51 Identities = 123/366 (33%), Positives = 176/366 (48%), Gaps = 9/366 (2%) Query: 74 GFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCFVGM 133 G L+GA FD FFG+S R+A PQQR+ + + W ALE++GI PGS AGT+ G FVG+ Sbjct: 52 GSLEGAADFDAAFFGMSPRQAAAADPQQRLMLELGWTALEDAGIVPGSLAGTDTGVFVGI 111 Query: 134 SPMEYGPRASVADA-YSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXXXXX 192 + +Y ++ SGH L + A R+S+ LGL GPS++VD+ Sbjct: 112 AADDYAALLHRSETPVSGHTATGLSRGMAANRLSYLLGLRGPSLAVDSAQSSSLVAVHLA 171 Query: 193 XXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGAGMV 252 +R E + A+ G V ++ + + + ALS DG C + A G V GEG V Sbjct: 172 CESLRHGESDLAIVGGVSLILAENSTAGMELMGALSPDGRCYTFDARANGYVRGEGGACV 231 Query: 253 LVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPVEVG 312 ++ N++G G + P AQE V+R E +G+ P +V Sbjct: 232 VLKPLDRALADGDRVHCVIRGSAVNNDGGGSTLTTPHREAQEAVLRAAYERSGVGPDQVS 291 Query: 313 MIEGHGTATPAGDPVELIALFKTYGAAGSEAL---LGSIKSNAGHSQXXXXXXXXXXXXX 369 +E HGT TPAGDP+E AL G A + +GS K+N GH + Sbjct: 292 YVELHGTGTPAGDPIEAAALGAVLGTARGRSTPLSVGSAKTNVGHLEAAAGLVGFVKAAL 351 Query: 370 XXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHG-----VRYGAVSSFGAGGA 424 + G +PP+L P + D LR+ T+L W G +R VSSFG GG Sbjct: 352 CVREGVVPPSLNHATPNPAIPMDRLNLRVPTRLDTWPQPDGQATGRLRLAGVSSFGMGGT 411 Query: 425 NAHAII 430 NAH ++ Sbjct: 412 NAHVVV 417 >tr|Q2PC83|Q2PC83_STRAH Tax_Id=285531 (rubA)SubName: Full=Putative polyketide synthase;[Streptomyces achromogenes subsp. rubradiris] Length = 5349 Score = 308 bits (789), Expect = 9e-82 Identities = 163/423 (38%), Positives = 215/423 (50%), Gaps = 3/423 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +P+VI GMA PGGI P LW ++E R+ PFP DRGW ++ L Sbjct: 1003 EPVVIVGMACRLPGGITGPDELWRLVSEGRDASGPFPADRGWDLERLFDADPGRAGTSYV 1062 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 D GGFLDGA FD FFGIS REA+ + PQQR+ + AW+ALE++GI+ S GT+ G F Sbjct: 1063 DRGGFLDGAAEFDADFFGISPREALAMDPQQRLLLETAWEALEHAGIDASSLRGTDAGVF 1122 Query: 131 VGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXXX 190 G+ YG V + + + RIS+ LGL GP+I+VDT Sbjct: 1123 AGLMEQGYGTGGPVPEELEAFQTTGTAGSVASGRISYLLGLRGPAITVDTACSSSLVALH 1182 Query: 191 XXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGAG 250 +R EC ALAG VM +P +F EF+R AL+ DG C++Y+ A GT W EGAG Sbjct: 1183 LAAHALRRGECSLALAGGATVMATPQSFVEFSRQRALAADGRCKSYASAADGTAWAEGAG 1242 Query: 251 MVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPVE 310 M+++ N +G + P AQ++VIR+ L AG+ P + Sbjct: 1243 MLVLERLGDARRNGHRILAVLRGSSVNSDGASNGLTAPSGEAQQRVIRQALTSAGLGPAD 1302 Query: 311 VGMIEGHGTATPAGDPVELIALFKTYGA---AGSEALLGSIKSNAGHSQXXXXXXXXXXX 367 + +EGHGT T GDP+E AL TYG AG LGS+KSN GH+Q Sbjct: 1303 IDAVEGHGTGTVLGDPIEAEALLATYGRDRDAGQPLWLGSLKSNVGHTQAAAGVAGVIKM 1362 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 +HG +P TL D PT VDW + L T+ W R +S FG G NAH Sbjct: 1363 IQALRHGVLPATLNVDEPTSRVDWSSGAVALLTENRTWPDLGRPRRAGISGFGLSGTNAH 1422 Query: 428 AII 430 I+ Sbjct: 1423 VIV 1425 Score = 294 bits (753), Expect = 1e-77 Identities = 163/429 (37%), Positives = 215/429 (50%), Gaps = 4/429 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GM V PGG++SP LW + E R+ +S FP DRGW D L Sbjct: 3726 EPIAIIGMGVRLPGGVESPDDLWRLVIERRDAISGFPTDRGWDTDGLYHPDPAHPGTTYT 3785 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 SGGFL A FDPG FGIS REA+ + PQQR+ + +W+A+E +GI+P S G E G F Sbjct: 3786 RSGGFLYDAAQFDPGLFGISPREALAMDPQQRLLLEASWEAMERAGIDPLSARGEEIGVF 3845 Query: 131 VGMSPMEYGPRAS-VADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 G+ +Y R + + + G+ + + RI++ G GP++++DT Sbjct: 3846 TGIVHHDYATRLNRIPEEVRGYVMTGTSPSVASGRIAYVFGFEGPAVTLDTACSSSLVAI 3905 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC ALAG VM SP AF EF+ LS DG C+ +S A GT W EGA Sbjct: 3906 HQAAQALRHGECTMALAGGATVMASPEAFVEFSSQRGLSADGRCKTFSSTADGTGWSEGA 3965 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G+VL+ N +G + P AQ++VIR+ L AGI P Sbjct: 3966 GVVLLERLSVARQRGHRVLATIRGSAVNSDGVSNGLTAPNGAAQQRVIRRALASAGIGPA 4025 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGA---AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +V +E HGT T GDP+E AL TYG AG LGS+KSN GH+Q Sbjct: 4026 DVDAVEAHGTGTVLGDPIEAGALLATYGEARDAGQPLWLGSLKSNIGHTQAAAGVAGVIK 4085 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +H +PPT+ + PT VDW L L T+ EW R VS+FGA G NA Sbjct: 4086 MVEALRHRVLPPTIHVEEPTGQVDWSAGTLALLTEPREWPRTGRPRRAGVSAFGASGTNA 4145 Query: 427 HAIISMPAA 435 H I+ A Sbjct: 4146 HLILEQAPA 4154 Score = 281 bits (720), Expect = 9e-74 Identities = 159/427 (37%), Positives = 210/427 (49%), Gaps = 3/427 (0%) Query: 7 AGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGW 66 A A +PI I MA PGG+ SP LW L+ + ++ FP DRGW L Sbjct: 2690 ATAGEPIAIVAMACRFPGGVHSPEDLWRILSTETDTVTEFPTDRGWDTARLFDPDPDHPG 2749 Query: 67 GQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTE 126 G FLD FD GFFGIS +EA+ PQQR+ M +W+ LE +GI+P S + Sbjct: 2750 TTYVRHGAFLDDPGAFDAGFFGISPQEALAKDPQQRLVMETSWELLERAGIDPHSLHAQD 2809 Query: 127 GGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXX 186 G FVG++ ++ R A G R+ + R+++ LGL GP+I+VDT Sbjct: 2810 VGVFVGVNSHDWTVRTHHASGVEGFRLTGSSGSVLSGRVAYHLGLEGPAITVDTACSSSL 2869 Query: 187 XXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWG 246 +R EC ALAG V VMG+ F EF+R L+ DG C+ +D A GT W Sbjct: 2870 VALHLAVQAIRNGECSMALAGGVMVMGTVETFIEFSRQPGLAPDGRCKGLADTAGGTGWS 2929 Query: 247 EGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGI 306 EG G++LV N +G + P +Q++VIRK L AG+ Sbjct: 2930 EGVGLLLVEPLSRAREQGHRVLALVRGTAVNSDGASNGLTAPNGPSQQRVIRKALAAAGL 2989 Query: 307 DPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXXXX 363 EV +EGHGT T GDP+E AL +TYG A LGS+KSN GH+Q Sbjct: 2990 RGDEVDSVEGHGTGTTLGDPIEAQALLETYGRDRPADRPLWLGSVKSNIGHTQAAAGVAG 3049 Query: 364 XXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGG 423 +HG +P TL D P+ VDW +RL T+ +W R VSSFG GG Sbjct: 3050 VIKMVMAMRHGVLPRTLHVDRPSTHVDWSAGAVRLLTERRDWPRAGQPRRAGVSSFGIGG 3109 Query: 424 ANAHAII 430 NAH I+ Sbjct: 3110 TNAHVIL 3116 >tr|C1YLQ5|C1YLQ5_NOCDA Tax_Id=446468 SubName: Full=Polyketide synthase family protein;[Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length = 1126 Score = 308 bits (789), Expect = 9e-82 Identities = 167/427 (39%), Positives = 224/427 (52%), Gaps = 5/427 (1%) Query: 10 ADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQV 69 +DP+ + GM PGG+DSP LW + + + + PFP DRGW +D +L S+ Sbjct: 36 SDPVAVVGMGCRLPGGVDSPEGLWDLVEQGTDAIGPFPEDRGWDLDAVLGGSEPLS---A 92 Query: 70 CDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGC 129 D GGFL+GA FD FFGIS +EA + PQQR+ + ++W+ALE +GI+P S AGT G Sbjct: 93 MDQGGFLEGAADFDAAFFGISPKEAAAMDPQQRLLLELSWEALERAGIDPSSLAGTPTGV 152 Query: 130 FVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 +VG+ EYGPR S A GH + + RI+++LGL GP+++VDT Sbjct: 153 YVGLMAAEYGPRLSDAPE-DGHLLTGTMPSVASGRIAYTLGLAGPALTVDTACSSSLVAL 211 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +RE EC AL G VMG+PG EF+R LS DG CRA+ A GT + EGA Sbjct: 212 HLAVRALRERECSLALVGGATVMGTPGVLAEFSRKQGLSADGRCRAFGAGANGTGFAEGA 271 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G +++ N +G + P +Q V+R L+ AGI P Sbjct: 272 GALVLERLSDARRNGHRVLALVRGSAVNQDGASNGLTAPNGPSQVSVVRAALDDAGISPD 331 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGA-AGSEALLGSIKSNAGHSQXXXXXXXXXXXX 368 V +E HGT T GDP+E AL + YG G+ L+GS+KSN GH+Q Sbjct: 332 GVDAVEAHGTGTTLGDPIEAQALIEAYGGERGAPLLVGSLKSNIGHTQAAAGVSGVVKAV 391 Query: 369 XXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAHA 428 HG + PTL A+ P+ VDWD +RLAT+ H VSSFG G NAH Sbjct: 392 QSLLHGTVAPTLHAEEPSTHVDWDSGAVRLATRAHPLPDLGRPARIGVSSFGISGTNAHV 451 Query: 429 IISMPAA 435 I+ P A Sbjct: 452 ILEAPPA 458 >tr|Q6W5P6|Q6W5P6_9ACTO Tax_Id=206662 (fscD)SubName: Full=FscD;[Streptomyces sp. FR-008] Length = 9550 Score = 306 bits (785), Expect = 3e-81 Identities = 174/435 (40%), Positives = 226/435 (51%), Gaps = 9/435 (2%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 +A A DP+VI GM+ PG + SP LW + + + FP DRGW ++ LL D +G Sbjct: 7926 AADADDPVVIVGMSCRYPGDVRSPEDLWELVGAGTDAIGGFPTDRGWDLEKLLH-GDEDG 7984 Query: 66 WGQ-VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAG 124 G+ V GGFL FDP FFGIS REA+V+ PQQR+ ++ AW+ALE +GI+P G Sbjct: 7985 RGRSVTREGGFLYDVADFDPAFFGISPREALVIDPQQRIVLQAAWEALERAGIDPAVLRG 8044 Query: 125 TEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 + G FVG +Y P A SGH + + R+S++LGL GPS+SVDT Sbjct: 8045 GDTGVFVGGGSGDYRP----AIGQSGHVETAQSASLLSGRLSYTLGLEGPSVSVDTACSS 8100 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R EC ALAG V VM +P F EF + ALS DG C+ +SD A GT Sbjct: 8101 SLTALHLAAQAIRSGECSLALAGGVTVMSTPVGFVEFGEMGALSPDGRCKPFSDAADGTA 8160 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 W EG GM++V N +G + P +Q++VIRK L A Sbjct: 8161 WSEGVGMLVVERLSEARRRGHEVLAVLRGSAINQDGASNGLTAPNGPSQQRVIRKALAAA 8220 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXX 361 G+ EV +E HGT T GDP+E AL TYG G LLGS+KSN GHSQ Sbjct: 8221 GLTAREVDAVEAHGTGTTLGDPIEAQALLATYGQDRPEGQPLLLGSVKSNIGHSQAASGV 8280 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +HG +P TL A+ P++ V WD + L T+ +W R AVSSFGA Sbjct: 8281 AGIIKMVLAMRHGTLPRTLHAEKPSRHVAWDPDAVHLLTEAADWPETGRPRRAAVSSFGA 8340 Query: 422 GGANAHAIISMPAAG 436 G NAH I+ G Sbjct: 8341 SGTNAHVILEQAPTG 8355 Score = 290 bits (742), Expect = 3e-76 Identities = 162/432 (37%), Positives = 214/432 (49%), Gaps = 12/432 (2%) Query: 7 AGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGW 66 A DP+V+ GM PGG++SP LW L E R+ +S FP DRGW +D L Sbjct: 6422 ATETDPVVVVGMGCRFPGGVESPEELWQLLGEGRDAVSGFPADRGWDLDSLAR------G 6475 Query: 67 GQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTE 126 G GGFL GA FD FFGIS REA+ + PQQR+ + +W+ALE +GI+P + Sbjct: 6476 GSATLEGGFLQGAGLFDASFFGISPREALAMDPQQRLLLETSWEALERAGIDPTGLRSSA 6535 Query: 127 GGCFVGMSPMEYGP--RASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 G FVG + +Y R D GH + R+S++LGL GP+++VDT Sbjct: 6536 TGVFVGTNGQDYATVLRRGTTDV-RGHAATGTTASVMSGRLSYTLGLEGPAVTVDTACSS 6594 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R EC ALAG V VM SP AF EF L+ DG C+A++D A GT Sbjct: 6595 ALVALHMAAGALRSGECTLALAGGVSVMASPDAFVEFTAQGGLAGDGRCKAFADAADGTA 6654 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 WGEGAG++++ N +G + P RAQ++VIR+ L A Sbjct: 6655 WGEGAGVLVLERLSDARRHGHPVLAVLRGSAVNQDGASNGLTAPNGRAQQRVIRQALADA 6714 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAA---GSEALLGSIKSNAGHSQXXXXX 361 + P EV +E HGT T GDP+E AL YG LLG++KSN GH+Q Sbjct: 6715 HLTPAEVDAVEAHGTGTTLGDPIEAHALIAAYGEGRDPEQPLLLGTVKSNLGHTQAAAGA 6774 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 HG++P TL D P+ VDW + L + W R VS+FG Sbjct: 6775 AGVIKTVLALGHGELPRTLHVDAPSSHVDWSDGTVELLREHRAWPETGRARRAGVSAFGV 6834 Query: 422 GGANAHAIISMP 433 G NAH I+ P Sbjct: 6835 SGTNAHVILEQP 6846 Score = 281 bits (719), Expect = 1e-73 Identities = 158/441 (35%), Positives = 223/441 (50%), Gaps = 10/441 (2%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 SA A DPIVI GM+ PGG+ SP LW + E + + P +RGW +D L Sbjct: 1781 SATADDPIVIVGMSCRYPGGVGSPDDLWRLVTEGTDAIGGLPVNRGWDLDSLYHPDPDHP 1840 Query: 66 WGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGT 125 GGFL A FD GFFG+S REA+ QQR+ + +W A+E++GI+P G+ Sbjct: 1841 GTSYTRYGGFLHDAGEFDAGFFGMSPREALATDSQQRLLLEASWTAVEHAGIDPVGLRGS 1900 Query: 126 EGGCFVGMSPMEYGPRASVADA-YSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 G F G+ +Y A++AD + GH+ + + R+S++LGL GP+++VDT Sbjct: 1901 RTGVFAGVMYSDYS--ATLADERFEGHQGSGTAPSIASGRVSYALGLEGPAVTVDTACSS 1958 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R EC ALAG V VM +P + EF+R LS DG C+A+SD A G Sbjct: 1959 SLVAMHWAMQALRSGECSLALAGGVTVMSTPTSLIEFSRQRGLSPDGRCKAFSDEADGVG 2018 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 W EG GM+++ N +G + P +Q++VIR+ L+ A Sbjct: 2019 WSEGVGMLVLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALDTA 2078 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXX 361 G+ +V +E HGT T GDP+E AL TYG LLGS+KSN GH+Q Sbjct: 2079 GLTTADVDAVEAHGTGTALGDPIEAQALLATYGQDRPGDRPLLLGSVKSNIGHTQAAAGV 2138 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +HG++P TL A +P++ VDW+ +R+ + W R VSSFG Sbjct: 2139 AGIIKMVMAMRHGELPRTLHAGSPSRHVDWETGDVRILQEPEAWPETGRPRRAGVSSFGI 2198 Query: 422 GGANAHAII----SMPAAGVG 438 G NAH ++ S PA G Sbjct: 2199 SGTNAHVVLEQGESAPAGSTG 2219 Score = 271 bits (692), Expect = 2e-70 Identities = 156/432 (36%), Positives = 207/432 (47%), Gaps = 14/432 (3%) Query: 3 TNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSD 62 T A A +PI I GM+ PGG+ SP LW L + ++ P DRGW Sbjct: 31 TELEAAATEPIAIVGMSCRYPGGVSSPEDLWKMLVAGEDGITGMPEDRGWEA-------- 82 Query: 63 LEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGST 122 G G +GGFL A FDP FFGIS REA+ + PQQR+ + W+A E +GI+P Sbjct: 83 ALGEGPADFAGGFLHDAPAFDPDFFGISPREALSMDPQQRLLLETGWEAFERAGIDPAGV 142 Query: 123 AGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXX 182 G+ G FVG P +Y R D G ++ + R+S+ G +GP+++VDT Sbjct: 143 RGSRTGMFVGAMPQDY--RVGPDDDVQGFQLTGNATSILSGRLSYFFGAVGPAVTVDTAC 200 Query: 183 XXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATG 242 +R EC ALA V VM SP F EFAR L+ DG CR+++D A G Sbjct: 201 SSSLVALHLAAQSLRAGECSLALAAGVTVMASPTTFVEFARQGGLAADGRCRSFADAANG 260 Query: 243 TVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLE 302 T W EG G++++ N +G + P +Q++VI L Sbjct: 261 TGWSEGVGVLVLERLSEARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIESALV 320 Query: 303 VAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXX 359 A + +V +E HGT T GDPVE AL TYG A S LLGS+KSN H+Q Sbjct: 321 NARLTAADVDAVEAHGTGTVLGDPVEAQALLATYGQGREADSPLLLGSVKSNISHTQAAA 380 Query: 360 XXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGV-RYGAVSS 418 +HG +P TL D P+ VDW +RL T+ W + R +SS Sbjct: 381 GVAGVIKMVMAMRHGLLPRTLHVDQPSTHVDWSEGSVRLLTEPAPWPARENAPRRAGISS 440 Query: 419 FGAGGANAHAII 430 FG G NAH II Sbjct: 441 FGLSGTNAHTII 452 Score = 268 bits (686), Expect = 8e-70 Identities = 148/423 (34%), Positives = 207/423 (48%), Gaps = 3/423 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI + M+ PGG+ SP +LW +A + ++ FP DRGW D L Sbjct: 4873 EPIAVVAMSCRYPGGVTSPEALWELIAAGADAITGFPADRGWDADALYDPDPDRPGTTYS 4932 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL FD GFFGIS REA+ + PQQR+ + W+A+E +GI+P + G+ G F Sbjct: 4933 TQGGFLHDVADFDAGFFGISPREALAMDPQQRLLLETGWEAIERAGIDPATLRGSMTGTF 4992 Query: 131 VGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXXX 190 +G S +Y + ++ H I + R++++ GL GP++++DT Sbjct: 4993 IGASYQDYTAGGAGSEGAEDHLITGTISSVMSGRLAYTFGLEGPAVTLDTACSSSLVALH 5052 Query: 191 XXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGAG 250 +R E ALAG V VM +P AF F+R A++ DG C+AY++ A G EG G Sbjct: 5053 LACQSLRNGESTLALAGGVSVMATPQAFTGFSRQRAMAPDGRCKAYAEGADGMSLAEGVG 5112 Query: 251 MVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPVE 310 +VLV N +G + P +Q +VIR+ L A + P E Sbjct: 5113 LVLVERLSDARRNGHPVLAVIRGSAVNQDGASNGLTAPNGPSQARVIRQALANARLTPGE 5172 Query: 311 VGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXXXXXXXX 367 V ++EGHGT T GDP+E AL TYG LLGS+KSN GH+Q Sbjct: 5173 VDVVEGHGTGTALGDPIEAQALLATYGQDRPGDRPLLLGSVKSNIGHTQMASGIAGVMKM 5232 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 +HG +P TL D P+ VDW + LAT+ W AVSSFG G N H Sbjct: 5233 VMAMRHGTVPRTLHVDTPSSHVDWGSGAIDLATETVPWPETGRPHRAAVSSFGLSGTNVH 5292 Query: 428 AII 430 I+ Sbjct: 5293 TIV 5295 Score = 259 bits (663), Expect = 4e-67 Identities = 149/433 (34%), Positives = 213/433 (49%), Gaps = 5/433 (1%) Query: 5 GSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLE 64 G A +PI I GM+ PGG S + W +A++ + +S FP +RGW D L Sbjct: 3337 GPAVTDEPIAIIGMSCRFPGGARSADAFWQLVADNTDAISEFPVNRGWDGDALYDPDPDR 3396 Query: 65 GWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAG 124 GGFL A FD GFFGIS REA+ + PQQR+ + W+A E++GI+P + Sbjct: 3397 PGTTYSTQGGFLHDAGEFDAGFFGISPREAVSMDPQQRLLLETTWEAFEHAGIDPAAVHS 3456 Query: 125 TEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 T G F+G + +YG S+ D +GH + + R+++S GL GP+++VDT Sbjct: 3457 TPTGTFIGSTYQDYG--VSMDDGSAGHAVTGSSPSVLSGRLAYSFGLEGPAVTVDTACSS 3514 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R E ALAG VM +P F F+R AL+ DG C+A+S++A G Sbjct: 3515 SLVALHLACQSLRNGETTLALAGGATVMTNPMPFIAFSRQRALARDGRCKAFSESADGMT 3574 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 EG G++++ N +G + P +Q +VIR+ L + Sbjct: 3575 LAEGVGILVLERLSDARRNGHEVLAVVRGSAINQDGASNGLTAPNGPSQVRVIRQALAAS 3634 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYGA---AGSEALLGSIKSNAGHSQXXXXX 361 G+ ++ +E HGT T GDP+E AL TYG + LLGS+KSN GH+Q Sbjct: 3635 GLTTDDIDAVEAHGTGTALGDPIEAQALHATYGRDRDPENPLLLGSVKSNIGHTQSAAGV 3694 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +HG +P TL A P+ +DW +RL T+ W AVSSFG Sbjct: 3695 AGIIKMVMAMRHGTLPRTLHATEPSSHIDWSGGTVRLVTENTGWARDDRPLRAAVSSFGI 3754 Query: 422 GGANAHAIISMPA 434 G NAHAI+ A Sbjct: 3755 SGTNAHAILEQAA 3767 >tr|Q5SFB4|Q5SFB4_STRBI Tax_Id=1896 (chmGI)SubName: Full=Polyketide synthase subunit;[Streptomyces bikiniensis] Length = 4441 Score = 306 bits (784), Expect = 3e-81 Identities = 166/423 (39%), Positives = 216/423 (51%), Gaps = 3/423 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GM PGG+ SP LW +A + +SPFP DRGW V L Sbjct: 1063 EPIAIVGMGCRLPGGVSSPEGLWDLVASGVDAVSPFPTDRGWDVGGLFDPEPGVPGRSYV 1122 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FD GFFGIS REA+ + PQQR+ + +W+ALE +GI+P + G+ G + Sbjct: 1123 REGGFLHEAGEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGIDPHTLRGSRTGVY 1182 Query: 131 VGMSPMEYGPRASV-ADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 G+ EYGPR AD Y G+ + + RIS+ LGL GP+++VDT Sbjct: 1183 AGVMAQEYGPRLHEGADGYEGYLLTGSSSSVASGRISYVLGLEGPAVTVDTACSSSLVAL 1242 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC+ ALAG VM PG F EF+R LS G C+AYSD+A GT W EGA Sbjct: 1243 HLAVRALRSGECDLALAGGATVMAEPGMFVEFSRQRGLSAHGRCKAYSDSADGTGWAEGA 1302 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G++LV N +G + P R+Q ++IR+ L A + Sbjct: 1303 GVLLVERLSDAVRHGRRVLAVVRGSAVNQDGASNGLTAPNGRSQSRLIRQALADARLGVA 1362 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXXX 367 +V ++EGHGT T GDP+E AL TYG AG LGS+KSN GH+Q Sbjct: 1363 DVDVVEGHGTGTRLGDPIEAQALLATYGQRDAGRPLRLGSLKSNVGHTQAAAGVAGVIKM 1422 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 +HG +P TL D PT VDW + L + W VR VSSFG G NAH Sbjct: 1423 VMAMRHGVLPKTLHVDEPTAEVDWSAGAVSLLREQEAWPRGERVRRAGVSSFGVSGTNAH 1482 Query: 428 AII 430 ++ Sbjct: 1483 VVV 1485 Score = 287 bits (735), Expect = 2e-75 Identities = 159/432 (36%), Positives = 215/432 (49%), Gaps = 3/432 (0%) Query: 2 STNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVS 61 +T +A +PI I GMA PG SP LW L + R+++ P P DRGW V L Sbjct: 2550 TTRPAAAPEEPIAIVGMACRYPGEARSPEELWKLLIDERDVIGPMPTDRGWDVGGLFDPE 2609 Query: 62 DLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGS 121 GGFL A FD GFFGIS REA+ + PQQR+ + +W+ALE +GI+P + Sbjct: 2610 PGVPGRSYVREGGFLHEAGEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGIDPHT 2669 Query: 122 TAGTEGGCFVGMSPMEYGPRASVADA-YSGHRIASLGQLGGAARISHSLGLIGPSISVDT 180 G++ G + GM EY R A + GH + + RIS+ LGL GP+++VDT Sbjct: 2670 LRGSQTGVYAGMFHQEYATRLHEAPVEFEGHLLTGTSGSVASGRISYVLGLEGPAVTVDT 2729 Query: 181 XXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA 240 +R EC+ ALAG V VM PG F EF+R L+ DG C+A++ A Sbjct: 2730 ACSSSLVALHLAVRALRSGECDLALAGGVTVMAEPGVFVEFSRQRGLAADGRCKAFAAAA 2789 Query: 241 TGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKT 300 GT W EG G++ V N +G + P +Q++VIR+ Sbjct: 2790 DGTGWAEGVGVLAVERLSDAVRHGRRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQA 2849 Query: 301 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXX 358 L A + +V ++EGHGT T GDP+E AL TYG AG LGS+KSN GH+Q Sbjct: 2850 LADARLGVADVDVVEGHGTGTRLGDPIEAQALLATYGQRDAGRPLRLGSLKSNVGHTQAA 2909 Query: 359 XXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSS 418 +HG +P TL D + VDW + L T+ W VR VS+ Sbjct: 2910 AGVAGVIKMVMAMRHGVLPKTLHVDEVSPHVDWSAGAVSLLTEQEPWPRGERVRRAGVSA 2969 Query: 419 FGAGGANAHAII 430 FG G NAH ++ Sbjct: 2970 FGVSGTNAHVVV 2981 Score = 205 bits (521), Expect = 1e-50 Identities = 145/452 (32%), Positives = 201/452 (44%), Gaps = 27/452 (5%) Query: 3 TNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSD 62 T GSAG PI G+++ G + + A + S L D W + Sbjct: 41 TTGSAGVTAPIDRPGVSMAPKSGAQRSSDI-AVVGMSCRLPGAPGIDEFWHL-------- 91 Query: 63 LEGWGQVCDSG------GFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSG 116 L G + G LDGA FD FF ++ R+A PQQR+ + + W ALEN+G Sbjct: 92 LTTGGSAIERRADGTWRGSLDGAADFDAAFFDMTPRQAAAADPQQRLMLELGWTALENAG 151 Query: 117 INPGSTAGTEGGCFVGMSPMEYGPRA-SVADAYSGHRIASLGQLGGAARISHSLGLIGPS 175 I PGS AGT+ G FVG++ +Y A SGH L + A R+S+ LGL GPS Sbjct: 152 IVPGSLAGTDTGVFVGIAADDYAALLHRSATPVSGHTATGLSRGMAANRLSYLLGLRGPS 211 Query: 176 ISVDTXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRA 235 ++VD+ +R E + A+ G V ++ + + + ALS DG C Sbjct: 212 LAVDSAQSSSLVAVHLACESLRRGESDLAIVGGVSLILAEDSTAGMELMGALSPDGRCHT 271 Query: 236 YSDNATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQ 295 + A G V GEG V++ N++G G + P AQ Sbjct: 272 FDARANGYVRGEGGACVVLKPLERALADGDRVHCVVRGSAVNNDGGGSTLTTPHREAQAA 331 Query: 296 VIRKTLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAA-GSEALL--GSIKSNA 352 V+R E AG+ P +V +E HGT TP GDPVE AL G A G A L GS+K+N Sbjct: 332 VLRAAYERAGVGPDQVSYVELHGTGTPVGDPVEAAALGAVLGTAHGRNAPLSVGSVKTNV 391 Query: 353 GHSQXXXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEW-----EP 407 GH + + G +PP+L P + D LR+ T+L W Sbjct: 392 GHLEAAAGLVGFVKAALCVREGVVPPSLNHATPNPAIPMDRLNLRVPTRLEPWPHPDDRA 451 Query: 408 KHGVRYGAVSSFGAGGANAHAIIS---MPAAG 436 +R VSSFG GG NAH ++ +P AG Sbjct: 452 TGRLRLAGVSSFGMGGTNAHVVVEEAPLPEAG 483 >tr|Q1L0S6|Q1L0S6_STRHY Tax_Id=285527 SubName: Full=NapC;[Streptomyces hygroscopicus subsp. duamyceticus] Length = 2164 Score = 306 bits (783), Expect = 4e-81 Identities = 164/427 (38%), Positives = 218/427 (51%), Gaps = 3/427 (0%) Query: 7 AGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGW 66 A + P+ I GMA PGG+ SP LW ++E RE +S FP DRGW V+ L Sbjct: 30 AEKSQPVAIVGMACRLPGGVASPQDLWRLVSEGREGVSGFPEDRGWDVEGLFDADPGRAG 89 Query: 67 GQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTE 126 D GGFL GA FD GFFGIS REA+ + PQQR+ + V+W+ALE +GI+PG+ G++ Sbjct: 90 KSYTDRGGFLPGAGLFDAGFFGISPREALAMDPQQRLLLEVSWEALERAGIDPGTLKGSD 149 Query: 127 GGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXX 186 G F G+ YG R G+ + + R+S+ G GP+I+VDT Sbjct: 150 VGVFSGVITQGYGMRGETPPELGGYLATGVVSSVASGRVSYVFGFEGPAITVDTACSSSL 209 Query: 187 XXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWG 246 +R+ EC ALAG VM +P F EF+R +S DG C+AYS A GT W Sbjct: 210 VAMHLAAQALRQGECSMALAGGATVMANPATFVEFSRQRVMSSDGRCKAYSATADGTGWA 269 Query: 247 EGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGI 306 EGAG+V++ N +G + P +Q++VIRK L AG+ Sbjct: 270 EGAGVVVLELLSEARRNGHQVLAVIRSSAVNQDGASNGLTAPNGPSQQRVIRKALASAGL 329 Query: 307 DPVEVGMIEGHGTATPAGDPVELIALFKTYGA---AGSEALLGSIKSNAGHSQXXXXXXX 363 +V ++EGHGT T GDP+E AL TYG LGS+KSN GH+Q Sbjct: 330 SAADVDVVEGHGTGTVLGDPIEAQALLATYGQNRHPERPLWLGSLKSNLGHTQAAAGVAS 389 Query: 364 XXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGG 423 +HG +P TL AD P+ VDW + L T+ +W R AVSSF G Sbjct: 390 VIKTVEALRHGVMPATLHADTPSSQVDWSAGAVELLTEARDWPDTGRPRRAAVSSFSMSG 449 Query: 424 ANAHAII 430 NAH I+ Sbjct: 450 TNAHLIL 456 >tr|Q82QT4|Q82QT4_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 7746 Score = 305 bits (782), Expect = 6e-81 Identities = 166/428 (38%), Positives = 219/428 (51%), Gaps = 4/428 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I M+ PGG+ SP LW LA + +S FP DRGW V+ L Sbjct: 1046 EPIAIVAMSCRLPGGVSSPEDLWRLLASGGDGISGFPTDRGWDVETLYDPEPGTPGKSST 1105 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FD GFFGIS REA + PQQR+ + AW+A E +GI+P + G+ G F Sbjct: 1106 RHGGFLHEAAEFDAGFFGISPREAAAIDPQQRLVLETAWEAFERAGIDPATLRGSRAGVF 1165 Query: 131 VGMSPMEYGPRA-SVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 +G + +YGPR AD G+ + + R+++S GL GP+++VDT Sbjct: 1166 IGATAQDYGPRLHEPADGVEGYLLTGTTTSVASGRVAYSFGLEGPAVTVDTACSSSLVAL 1225 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC ALAG V VM +PG F EF+R LS DG C+A++ A GT W EG Sbjct: 1226 HLAVQSLRSGECTMALAGGVTVMSTPGMFVEFSRQRGLSADGRCKAFAAGADGTGWAEGV 1285 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 GM+LV N +G + P +Q++V+R+ L AG+ P Sbjct: 1286 GMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRQALAAAGLAPA 1345 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGAA--GSEAL-LGSIKSNAGHSQXXXXXXXXXX 366 +V +E HGT T GDP+E AL YG G L LGS+KSN GH+Q Sbjct: 1346 DVDAVEAHGTGTLLGDPIEAEALIAAYGQGRDGDRPLWLGSLKSNIGHTQAAAGVAGVIK 1405 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +HG +P TL D PT VDW +G+RL T+ EW + R AVSSFG G NA Sbjct: 1406 MVMAMRHGVLPRTLHVDEPTPHVDWSASGVRLLTEAVEWPARDLPRRAAVSSFGISGTNA 1465 Query: 427 HAIISMPA 434 H I+ A Sbjct: 1466 HVIVEQAA 1473 Score = 297 bits (760), Expect = 2e-78 Identities = 165/439 (37%), Positives = 221/439 (50%), Gaps = 5/439 (1%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 +A A +P+ I GM+ PGG+ SP LW L+ R+ +S FP DRGW +D L Sbjct: 2547 AAAADEPLAIVGMSCRLPGGVQSPEDLWELLSSGRDAMSGFPTDRGWDIDALYDPDPDRP 2606 Query: 66 WGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGT 125 GGF+ GA FD G FGIS REA+ + PQQR+ + AW+A E +GI S + Sbjct: 2607 GKTYSREGGFIQGADRFDAGLFGISPREALAMDPQQRLLLETAWEAFERAGIALASVRAS 2666 Query: 126 EGGCFVGMSPMEYGPRASVA-DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 G F+G + +Y A + G+ + + RIS++ GL GP+++VDT Sbjct: 2667 RTGVFIGTNGQDYANGLRNAPEEIEGYALTGKAASVVSGRISYTFGLEGPAVTVDTACSS 2726 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R EC AL G V VM +P F EF+R LS DG C+A++ A GT Sbjct: 2727 SLVALHLAAQALRSGECSMALVGGVTVMTTPDLFVEFSRQRGLSPDGRCKAFAAGADGTG 2786 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 WGEG G++LV N +G + P +Q++VIR+ L A Sbjct: 2787 WGEGVGLLLVERLSDARRNGHQVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASA 2846 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE---ALLGSIKSNAGHSQXXXXX 361 G+ P +V +E HGT T GDP+E AL TYG S+ LGS+KSN GH+Q Sbjct: 2847 GLTPADVDAVEAHGTGTRLGDPIEAQALLATYGQEHSDDRPVWLGSVKSNIGHTQAAAGV 2906 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +HG +P TL D PT VDW +RL T+ +W G R AVSSFG Sbjct: 2907 AGVIKMVLAMRHGVLPQTLHVDEPTAHVDWSAGAVRLLTEPVQWPGTTGPRRAAVSSFGI 2966 Query: 422 GGANAHAII-SMPAAGVGQ 439 GG NAH II PAA + Sbjct: 2967 GGTNAHTIIEEAPAAAAAE 2985 Score = 296 bits (757), Expect = 5e-78 Identities = 167/435 (38%), Positives = 217/435 (49%), Gaps = 7/435 (1%) Query: 6 SAGAAD-PIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLE 64 + G AD PI I GMA PGG+ SP LW + R+ +S FP RGW V+ L + + Sbjct: 4280 ATGTADEPIAIVGMACRYPGGVQSPEDLWQLVFSGRDAVSGFPEGRGWDVEQLYDPNP-D 4338 Query: 65 GWG-QVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 WG GGFL A FD FFGIS REA+ + PQQR+ + +W+A E +GI+P + Sbjct: 4339 QWGTSYTREGGFLHDAADFDAEFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATVR 4398 Query: 124 GTEGGCFVGMSPMEYGPRASVA-DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXX 182 G+ G F G+ +YG R + G+ + + R+S++ GL GP+++VDT Sbjct: 4399 GSRTGVFAGVMYHDYGGRVHTSPPGLEGYLVNGSAGSIASGRVSYTFGLEGPAVTVDTAC 4458 Query: 183 XXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATG 242 +R EC AL G V VM P F EF+R LS DG C+A+ A G Sbjct: 4459 SSSLVALHLAAQALRSGECSMALVGGVTVMAGPSVFVEFSRQRGLSADGRCKAFGAGADG 4518 Query: 243 TVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLE 302 T W EG GM+LV N +G + P +Q++VIR+ L Sbjct: 4519 TGWAEGVGMLLVERLSDARRNGHKVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALA 4578 Query: 303 VAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE---ALLGSIKSNAGHSQXXX 359 AG+ EV +E HGT T GDP+E AL TYG SE LGS+KSN GHSQ Sbjct: 4579 NAGLSSDEVDAVEAHGTGTRLGDPIEAQALIATYGQERSEDRPLWLGSLKSNIGHSQAAA 4638 Query: 360 XXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSF 419 QHG +P TL D PT VDW ++L T+ EW G R AVSSF Sbjct: 4639 GVGGVIKMVMAMQHGVLPQTLHVDEPTPHVDWSAGAVQLLTEAVEWPASDGPRRAAVSSF 4698 Query: 420 GAGGANAHAIISMPA 434 G G NAH I+ A Sbjct: 4699 GVSGTNAHVIVEQAA 4713 Score = 293 bits (751), Expect = 2e-77 Identities = 166/430 (38%), Positives = 217/430 (50%), Gaps = 10/430 (2%) Query: 8 GAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWG 67 G + I I GMA PG + SP LW +A + +S FP DRGW V++L Sbjct: 5969 GTDEAIAIVGMACRFPGDVRSPEDLWRLVASGGDAISGFPEDRGWDVENLYDPDPDRSGK 6028 Query: 68 QVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEG 127 GGFL A FDP FFGIS REA+ + PQQR+ + +W+A E +GI+P + G+ Sbjct: 6029 SYVRHGGFLHEAAEFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATVRGSRT 6088 Query: 128 GCFVGMSPMEYGPRASVA----DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXX 183 G F G+ +YG R A DAY G S G + + R+S++ GL GP+++VDT Sbjct: 6089 GVFAGVMYHDYGGRVKTAPEGMDAYLGS--GSAGSIA-SGRVSYTFGLEGPAVTVDTACS 6145 Query: 184 XXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGT 243 +R EC AL G V VM +P F EF+R LS DG C+A++ A GT Sbjct: 6146 SSLVALHLATQALRSGECSMALVGGVTVMATPSTFVEFSRQRGLSADGRCKAFAAGADGT 6205 Query: 244 VWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEV 303 W EGAGM+LV N +G + P +Q++VIR+ L Sbjct: 6206 GWAEGAGMLLVERLSDARRNGHTVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALAN 6265 Query: 304 AGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG--AAGSEAL-LGSIKSNAGHSQXXXX 360 AG+ +V +E HGT T GDP+E AL TYG G L LGS+KSN GH+Q Sbjct: 6266 AGVSSEQVDAVEAHGTGTKLGDPIEAQALIATYGQERPGDRPLWLGSLKSNIGHAQAAAG 6325 Query: 361 XXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFG 420 +HG +P TL D PT VDW +RL T+ EW R AVSSFG Sbjct: 6326 VGGVIKMVMAMRHGALPRTLHVDEPTPHVDWSAGDVRLLTEAMEWPETDHPRRAAVSSFG 6385 Query: 421 AGGANAHAII 430 G NAH I+ Sbjct: 6386 ISGTNAHVIV 6395 Score = 221 bits (562), Expect = 2e-55 Identities = 145/438 (33%), Positives = 206/438 (47%), Gaps = 10/438 (2%) Query: 4 NGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDL 63 + SA +AD I + G+A PG D PA+ W L+E + ++ P DR W + S Sbjct: 15 SASADSADGIAVIGLACRLPGAAD-PAAFWRLLSEGADAITDVPPDR-WDGAVVADASAP 72 Query: 64 EGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 + G GGFLD FD GFFG+S +EA + PQQR+ + +AW+ALE++ + + Sbjct: 73 DRTG--IRRGGFLDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALEDAHVRAATLR 130 Query: 124 GTEGGCFVGMSPMEYGP--RASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTX 181 T G FVG +Y S A S H + L + A R+S+ LGL GPS++VD+ Sbjct: 131 STRTGVFVGAMWDDYATLHHRSGLTAISPHTVTGLHRSIIANRVSYFLGLNGPSLTVDSG 190 Query: 182 XXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNAT 241 +R+ E ALAG V + P + A+ LS DG C + A Sbjct: 191 QSSSLVSVHLACESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDGRCFTFDARAN 250 Query: 242 GTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTL 301 G V GEG G+V++ N++G G + VP QEQV+R Sbjct: 251 GYVRGEGGGIVVLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQSGQEQVLRLAY 310 Query: 302 EVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAA---GSEALLGSIKSNAGHSQXX 358 E AG++P +VG +E HGT T GDP+E AL G G +GS K+N GH + Sbjct: 311 ERAGVNPADVGYVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSAKTNVGHLEGA 370 Query: 359 XXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHG-VRYGAVS 417 H ++P +L P + D LR+ T+ EW + G VS Sbjct: 371 AGITGLLKAVLSLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAEDGRPLLAGVS 430 Query: 418 SFGAGGANAHAIISMPAA 435 SFG GG N H +++ AA Sbjct: 431 SFGMGGTNCHIVLASGAA 448 >tr|Q93H87|Q93H87_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 6048 Score = 305 bits (782), Expect = 6e-81 Identities = 166/428 (38%), Positives = 219/428 (51%), Gaps = 4/428 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I M+ PGG+ SP LW LA + +S FP DRGW V+ L Sbjct: 1046 EPIAIVAMSCRLPGGVSSPEDLWRLLASGGDGISGFPTDRGWDVETLYDPEPGTPGKSST 1105 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FD GFFGIS REA + PQQR+ + AW+A E +GI+P + G+ G F Sbjct: 1106 RHGGFLHEAAEFDAGFFGISPREAAAIDPQQRLVLETAWEAFERAGIDPATLRGSRAGVF 1165 Query: 131 VGMSPMEYGPRA-SVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 +G + +YGPR AD G+ + + R+++S GL GP+++VDT Sbjct: 1166 IGATAQDYGPRLHEPADGVEGYLLTGTTTSVASGRVAYSFGLEGPAVTVDTACSSSLVAL 1225 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC ALAG V VM +PG F EF+R LS DG C+A++ A GT W EG Sbjct: 1226 HLAVQSLRSGECTMALAGGVTVMSTPGMFVEFSRQRGLSADGRCKAFAAGADGTGWAEGV 1285 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 GM+LV N +G + P +Q++V+R+ L AG+ P Sbjct: 1286 GMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRQALAAAGLAPA 1345 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGAA--GSEAL-LGSIKSNAGHSQXXXXXXXXXX 366 +V +E HGT T GDP+E AL YG G L LGS+KSN GH+Q Sbjct: 1346 DVDAVEAHGTGTLLGDPIEAEALIAAYGQGRDGDRPLWLGSLKSNIGHTQAAAGVAGVIK 1405 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +HG +P TL D PT VDW +G+RL T+ EW + R AVSSFG G NA Sbjct: 1406 MVMAMRHGVLPRTLHVDEPTPHVDWSASGVRLLTEAVEWPARDLPRRAAVSSFGISGTNA 1465 Query: 427 HAIISMPA 434 H I+ A Sbjct: 1466 HVIVEQAA 1473 Score = 297 bits (760), Expect = 2e-78 Identities = 165/439 (37%), Positives = 221/439 (50%), Gaps = 5/439 (1%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 +A A +P+ I GM+ PGG+ SP LW L+ R+ +S FP DRGW +D L Sbjct: 2547 AAAADEPLAIVGMSCRLPGGVQSPEDLWELLSSGRDAMSGFPTDRGWDIDALYDPDPDRP 2606 Query: 66 WGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGT 125 GGF+ GA FD G FGIS REA+ + PQQR+ + AW+A E +GI S + Sbjct: 2607 GKTYSREGGFIQGADRFDAGLFGISPREALAMDPQQRLLLETAWEAFERAGIALASVRAS 2666 Query: 126 EGGCFVGMSPMEYGPRASVA-DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 G F+G + +Y A + G+ + + RIS++ GL GP+++VDT Sbjct: 2667 RTGVFIGTNGQDYANGLRNAPEEIEGYALTGKAASVVSGRISYTFGLEGPAVTVDTACSS 2726 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R EC AL G V VM +P F EF+R LS DG C+A++ A GT Sbjct: 2727 SLVALHLAAQALRSGECSMALVGGVTVMTTPDLFVEFSRQRGLSPDGRCKAFAAGADGTG 2786 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 WGEG G++LV N +G + P +Q++VIR+ L A Sbjct: 2787 WGEGVGLLLVERLSDARRNGHQVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASA 2846 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE---ALLGSIKSNAGHSQXXXXX 361 G+ P +V +E HGT T GDP+E AL TYG S+ LGS+KSN GH+Q Sbjct: 2847 GLTPADVDAVEAHGTGTRLGDPIEAQALLATYGQEHSDDRPVWLGSVKSNIGHTQAAAGV 2906 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +HG +P TL D PT VDW +RL T+ +W G R AVSSFG Sbjct: 2907 AGVIKMVLAMRHGVLPQTLHVDEPTAHVDWSAGAVRLLTEPVQWPGTTGPRRAAVSSFGI 2966 Query: 422 GGANAHAII-SMPAAGVGQ 439 GG NAH II PAA + Sbjct: 2967 GGTNAHTIIEEAPAAAAAE 2985 Score = 296 bits (757), Expect = 5e-78 Identities = 167/435 (38%), Positives = 217/435 (49%), Gaps = 7/435 (1%) Query: 6 SAGAAD-PIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLE 64 + G AD PI I GMA PGG+ SP LW + R+ +S FP RGW V+ L + + Sbjct: 4280 ATGTADEPIAIVGMACRYPGGVQSPEDLWQLVFSGRDAVSGFPEGRGWDVEQLYDPNP-D 4338 Query: 65 GWG-QVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 WG GGFL A FD FFGIS REA+ + PQQR+ + +W+A E +GI+P + Sbjct: 4339 QWGTSYTREGGFLHDAADFDAEFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATVR 4398 Query: 124 GTEGGCFVGMSPMEYGPRASVA-DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXX 182 G+ G F G+ +YG R + G+ + + R+S++ GL GP+++VDT Sbjct: 4399 GSRTGVFAGVMYHDYGGRVHTSPPGLEGYLVNGSAGSIASGRVSYTFGLEGPAVTVDTAC 4458 Query: 183 XXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATG 242 +R EC AL G V VM P F EF+R LS DG C+A+ A G Sbjct: 4459 SSSLVALHLAAQALRSGECSMALVGGVTVMAGPSVFVEFSRQRGLSADGRCKAFGAGADG 4518 Query: 243 TVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLE 302 T W EG GM+LV N +G + P +Q++VIR+ L Sbjct: 4519 TGWAEGVGMLLVERLSDARRNGHKVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALA 4578 Query: 303 VAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE---ALLGSIKSNAGHSQXXX 359 AG+ EV +E HGT T GDP+E AL TYG SE LGS+KSN GHSQ Sbjct: 4579 NAGLSSDEVDAVEAHGTGTRLGDPIEAQALIATYGQERSEDRPLWLGSLKSNIGHSQAAA 4638 Query: 360 XXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSF 419 QHG +P TL D PT VDW ++L T+ EW G R AVSSF Sbjct: 4639 GVGGVIKMVMAMQHGVLPQTLHVDEPTPHVDWSAGAVQLLTEAVEWPASDGPRRAAVSSF 4698 Query: 420 GAGGANAHAIISMPA 434 G G NAH I+ A Sbjct: 4699 GVSGTNAHVIVEQAA 4713 Score = 221 bits (562), Expect = 2e-55 Identities = 145/438 (33%), Positives = 206/438 (47%), Gaps = 10/438 (2%) Query: 4 NGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDL 63 + SA +AD I + G+A PG D PA+ W L+E + ++ P DR W + S Sbjct: 15 SASADSADGIAVIGLACRLPGAAD-PAAFWRLLSEGADAITDVPPDR-WDGAVVADASAP 72 Query: 64 EGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 + G GGFLD FD GFFG+S +EA + PQQR+ + +AW+ALE++ + + Sbjct: 73 DRTG--IRRGGFLDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALEDAHVRAATLR 130 Query: 124 GTEGGCFVGMSPMEYGP--RASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTX 181 T G FVG +Y S A S H + L + A R+S+ LGL GPS++VD+ Sbjct: 131 STRTGVFVGAMWDDYATLHHRSGLTAISPHTVTGLHRSIIANRVSYFLGLNGPSLTVDSG 190 Query: 182 XXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNAT 241 +R+ E ALAG V + P + A+ LS DG C + A Sbjct: 191 QSSSLVSVHLACESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDGRCFTFDARAN 250 Query: 242 GTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTL 301 G V GEG G+V++ N++G G + VP QEQV+R Sbjct: 251 GYVRGEGGGIVVLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQSGQEQVLRLAY 310 Query: 302 EVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAA---GSEALLGSIKSNAGHSQXX 358 E AG++P +VG +E HGT T GDP+E AL G G +GS K+N GH + Sbjct: 311 ERAGVNPADVGYVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSAKTNVGHLEGA 370 Query: 359 XXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHG-VRYGAVS 417 H ++P +L P + D LR+ T+ EW + G VS Sbjct: 371 AGITGLLKAVLSLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAEDGRPLLAGVS 430 Query: 418 SFGAGGANAHAIISMPAA 435 SFG GG N H +++ AA Sbjct: 431 SFGMGGTNCHIVLASGAA 448 >tr|Q0R4M8|Q0R4M8_STRAT Tax_Id=1890 SubName: Full=ChlA1;[Streptomyces antibioticus] Length = 4699 Score = 305 bits (782), Expect = 6e-81 Identities = 170/434 (39%), Positives = 224/434 (51%), Gaps = 4/434 (0%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 +A + DP+V+ GMA PGG+ SP LW +A+ R+ + P P +RGW ++ L Sbjct: 1082 AAVSDDPVVVVGMACRFPGGVGSPEQLWDLVAQGRDAIGPLPDNRGWDLEALYDPDPETP 1141 Query: 66 WGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGT 125 GGFL A FDP FFGIS REA + PQQR+ + +W+ALE +GI+P + AGT Sbjct: 1142 STSYVREGGFLYDADLFDPAFFGISPREAAAMDPQQRLLLETSWEALERAGIDPRTLAGT 1201 Query: 126 EGGCFVGMSPMEYGPRASV-ADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 G FVG + EYGPR S A+ G+ + + R++++LGL GP+++VDT Sbjct: 1202 AAGVFVGATAQEYGPRLSEGAEGLDGYLLTGTTTSVTSGRVAYTLGLHGPAVTVDTACSS 1261 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R ECE LAG V VM PG F EF+R LS DG C+A++ +A GT Sbjct: 1262 SLTALHLAAQALRLGECELVLAGGVTVMAGPGMFVEFSRQRGLSPDGRCKAFAASADGTG 1321 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 W EGAGMV++ N +G + P AQE VIR+ L A Sbjct: 1322 WAEGAGMVVLERLSDARRHGHRVLAVVRGSAINQDGASNGLAAPNGPAQEDVIRQALAAA 1381 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL---LGSIKSNAGHSQXXXXX 361 + E+ +E HGT T GDP+E AL TYG S L LGS+KSN GH+Q Sbjct: 1382 RLTGDEIDAVEAHGTGTKLGDPIEAEALLATYGRDRSPELPLWLGSLKSNIGHAQAAAGV 1441 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +HG +P TL AD PT VDW + L T+ W R AVSSFG Sbjct: 1442 GGFIKMVMALRHGVLPGTLHADEPTPHVDWSAGTVSLLTEARPWPQTDRPRRAAVSSFGI 1501 Query: 422 GGANAHAIISMPAA 435 G NAH I+ A Sbjct: 1502 SGTNAHLILEQAPA 1515 Score = 261 bits (668), Expect = 1e-67 Identities = 156/427 (36%), Positives = 210/427 (49%), Gaps = 6/427 (1%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 ++DPI I+G+ PGGI SP LW ++E E S FP RGW +D L Sbjct: 2892 SSDPIAITGIGCRFPGGIGSPEELWRLVSEGGEARSGFPSQRGWDLDALYDPDPDHPGTV 2951 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 GGFL A FD FFG+S REA+ PQQR+ + AW+ LE +G++P S G+ G Sbjct: 2952 YTRVGGFLYDAHHFDADFFGMSPREALATDPQQRLLLETAWETLERAGLDPRSLRGSRTG 3011 Query: 129 CFVGMSPMEYGPRASVA-DAYSGH-RIASLGQLGGAARISHSLGLIGPSISVDTXXXXXX 186 F G+ +YG R A + G+ R S G + + RI+++ G GP++SVDT Sbjct: 3012 VFTGIMYGDYGGRLQRAPEELEGYLRNGSHGSVA-SGRIAYTFGFEGPAVSVDTACSSSL 3070 Query: 187 XXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWG 246 +R EC+ ALAG V VM +P F EF+R LS DG C+A++ +A GT + Sbjct: 3071 VALHLAAQALRNGECDLALAGGVTVMATPATFIEFSRQRGLSADGRCKAFAASADGTGFA 3130 Query: 247 EGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGI 306 EG G++LV N +G + P +Q++VI+ L A + Sbjct: 3131 EGVGLLLVERLSDARRNGHRVLALLRGSAVNQDGASNGLTAPNGPSQQRVIQAALADARL 3190 Query: 307 DPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXXXX 363 +V +E HGT T GDP+E AL TYG LGSIKSN GH+Q Sbjct: 3191 TAGQVDAVEAHGTGTSLGDPIEAQALLATYGQDREPEQPLWLGSIKSNIGHTQAAAGVAG 3250 Query: 364 XXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGG 423 +HG +P TL D PT VDW + L + W R AVSSFG G Sbjct: 3251 VIKMVQAMRHGVLPQTLHVDEPTPHVDWAAGAVALLDETRPWPETGRPRRAAVSSFGISG 3310 Query: 424 ANAHAII 430 NAH I+ Sbjct: 3311 TNAHVIL 3317 Score = 201 bits (511), Expect = 2e-49 Identities = 132/380 (34%), Positives = 181/380 (47%), Gaps = 16/380 (4%) Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 + GG LD FD GFFGIS REA + PQQR+ + ++W+ALE++ I PG+ GG F Sbjct: 102 EHGGVLDRVDGFDAGFFGISPREATEMDPQQRLTLELSWEALEDAAIVPGTLRSGAGGVF 161 Query: 131 VGMSPMEYG-------PRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXX 183 VG +Y PR +G S G L G R+S++LGL GPS++VD Sbjct: 162 VGAIGDDYAALLARHRPREFTPHTLTG---TSRGLLAG--RVSYTLGLHGPSLTVDAAQS 216 Query: 184 XXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGT 243 +R EC+ ALAG V ++ P + A ALS DG C + A G Sbjct: 217 SSLVAVHLACESLRGGECDLALAGGVNLIIGPESTARTAAFGALSPDGRCYTFDARANGY 276 Query: 244 VWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEV 303 V GEG +V++ N++G + + VP RAQ +V+R+ Sbjct: 277 VRGEGGAVVVLKPLARALADGDRIHCVIRGSAVNNDGASEALTVPSGRAQAEVVRRACAR 336 Query: 304 AGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL---LGSIKSNAGHSQXXXX 360 AGI P EV +E HGT T GDPVE AL YGA + + +GS K+N GH + Sbjct: 337 AGIAPDEVQYVELHGTGTRVGDPVEAAALGSVYGAGRTRSTALRVGSAKTNVGHLEGAAG 396 Query: 361 XXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFG 420 H ++ P+L +P +D D LR+ T+ W VSSFG Sbjct: 397 ITGLVKTVLSIAHRRLVPSLHFRSPHPDIDLDALRLRVQTETGPWPAPDLPLVAGVSSFG 456 Query: 421 AGGANAHAIIS-MPAAGVGQ 439 GG N H I++ PAA G+ Sbjct: 457 MGGTNCHVILAEAPAARGGE 476 >tr|A1YAM7|A1YAM7_AMYOR Tax_Id=31958 SubName: Full=Polyketide synthase type I;[Amycolatopsis orientalis] Length = 5723 Score = 305 bits (782), Expect = 6e-81 Identities = 166/429 (38%), Positives = 220/429 (51%), Gaps = 2/429 (0%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 A +PI I M+ PG D+P LWA LAE R+ L FP DRGW ++ L Sbjct: 3626 ADEPIAIVAMSCRFPGHADTPERLWALLAEGRDALGEFPADRGWDLERLFDTDPDRRGTS 3685 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 G FL+ A FD GFFGIS REA+ + PQQR+ + +W+A E +GI+P + G+ G Sbjct: 3686 YTRQGAFLETAGDFDAGFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTG 3745 Query: 129 CFVGMSPMEY-GPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 F G+ EY A V D G+ + R+S++ GL GP+++VDT Sbjct: 3746 VFAGVMDNEYVSGSAEVPDGVEGYLATGTSASVASGRVSYTFGLEGPAVTVDTACSSSLV 3805 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R+ EC ALAG V VM +PG F EF+R L+ DG C+A++D A GT WGE Sbjct: 3806 ALHLAAQALRQGECSLALAGGVTVMATPGTFVEFSRQRGLAADGRCKAFADGADGTGWGE 3865 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 GAGM+LV N +G + P +Q++VIR+ L A ++ Sbjct: 3866 GAGMLLVERLSDARRNGHPVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLE 3925 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE-ALLGSIKSNAGHSQXXXXXXXXXX 366 P EV +E HGT T GDP+E AL TYG LLGS+KSN GH+Q Sbjct: 3926 PSEVDAVEAHGTGTTLGDPIEAQALLATYGQDRERPLLLGSVKSNIGHTQAAAGVAGVIK 3985 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +HG +P TL D PT VDW + LAT+ +W G R AVSSFG G NA Sbjct: 3986 MVLAMRHGTLPRTLHVDTPTSRVDWAAGRIELATEPTQWPETGGPRRAAVSSFGMSGTNA 4045 Query: 427 HAIISMPAA 435 H ++ A Sbjct: 4046 HVVLEQAEA 4054 Score = 290 bits (743), Expect = 2e-76 Identities = 166/431 (38%), Positives = 221/431 (51%), Gaps = 10/431 (2%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GMA PGG+ SP LW +A R L+ FP DRGW +D L + Sbjct: 39 EPIAIIGMACRYPGGVRSPEELWDLVAGERTGLTGFPVDRGWDLDGLYDPEQGKPGKSYV 98 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FDP FFGIS REA+ + PQQR+ + ++W+A+E +GI P S G+ G F Sbjct: 99 REGGFLHDAARFDPAFFGISPREALAMDPQQRLLLEISWEAIERAGIAPDSLRGSRTGVF 158 Query: 131 VGMSPMEYGPRASVADA----YSGH-RIASLGQLGGAARISHSLGLIGPSISVDTXXXXX 185 G+ EY A A Y G+ AS+ + R+S++ GL GP+++VDT Sbjct: 159 AGVIHNEYSAIAGTPPADLEPYLGNGSFASIA----SGRVSYTFGLEGPAVTVDTACSSS 214 Query: 186 XXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVW 245 +R+ EC ALAG V VM +P AF +F+R L+ DG +A+++ A GT W Sbjct: 215 LVALHLAAQALRQGECSLALAGGVTVMANPAAFVDFSRQRGLAADGRIKAFAEAADGTAW 274 Query: 246 GEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAG 305 GEGAGM+LV N +G + P +Q++VIR+ L A Sbjct: 275 GEGAGMLLVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGLSQQRVIRQALANAR 334 Query: 306 IDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXX 364 + P +V +E HGT T GDP+E AL TYG + L LGS+KSN GHSQ Sbjct: 335 LAPSDVDAMEAHGTGTRLGDPIEAQALLATYGQDRTTPLWLGSVKSNIGHSQAAAGVASI 394 Query: 365 XXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGA 424 +HG +P TL D PT VDW + L T+ W R AVSSFG G Sbjct: 395 IKLVEAMRHGVLPKTLHVDAPTSHVDWSEGAVSLLTEAEPWPKTDRPRRAAVSSFGISGT 454 Query: 425 NAHAIISMPAA 435 NAH ++ P A Sbjct: 455 NAHVVLEQPTA 465 Score = 288 bits (738), Expect = 7e-76 Identities = 170/439 (38%), Positives = 223/439 (50%), Gaps = 8/439 (1%) Query: 5 GSAGAAD-PIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDL 63 G A AAD PI I GMA PGG+ SP LW +AE R+ +S FP DRGW VD L Sbjct: 1650 GPAMAADEPIAIIGMACRYPGGVASPEDLWRLVAEGRDGISLFPADRGWDVDGLYDPDPG 1709 Query: 64 EGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 + GGFL A FD GFFGIS REA+ + PQQR+ + V+W+A E +GI+PG+ Sbjct: 1710 KAGKSYVREGGFLHEAGDFDAGFFGISPREALGMDPQQRLLLEVSWEAFERAGIDPGTLR 1769 Query: 124 GTEGGCFVGMSPMEYGPRASVA-DAYSGHRIASLGQLGG--AARISHSLGLIGPSISVDT 180 G++ G F G +Y A+V D G+ G G + R+S++ GL GP+++VDT Sbjct: 1770 GSDTGVFAGQMYHDYLTGATVVPDDVEGY--LGTGNSGSVLSGRVSYTFGLEGPAVTVDT 1827 Query: 181 XXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA 240 +R EC ALAG V VM +P F +F+R L+ DG +++SD A Sbjct: 1828 ACSSSLVALHLAAQALRRGECSLALAGGVTVMATPETFVDFSRQRGLAPDGRSKSFSDGA 1887 Query: 241 TGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKT 300 GT W EG GM+LV N +G + P +Q++VIR+ Sbjct: 1888 DGTSWSEGVGMLLVERLSDAERNGHRILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRRA 1947 Query: 301 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL--LGSIKSNAGHSQXX 358 L A ++P EV +E HGT T GDP+E AL TYG +A LGSIKSN GHSQ Sbjct: 1948 LADARLEPSEVDAVEAHGTGTTLGDPIEAQALLATYGQGREDAALWLGSIKSNIGHSQAA 2007 Query: 359 XXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSS 418 + G +P TL P+ VDW + L T+ W R AVSS Sbjct: 2008 AGVAGVIKMVEAMRRGVLPKTLHVTEPSSHVDWTAGAVSLLTEARLWPDAGRPRRAAVSS 2067 Query: 419 FGAGGANAHAIISMPAAGV 437 FG G NAH ++ A V Sbjct: 2068 FGISGTNAHVVLEQGPAPV 2086 >tr|O33954|O33954_STRFR Tax_Id=1906 (tylG)SubName: Full=Tylactone synthase starter module and modules 1 & 2;[Streptomyces fradiae] Length = 4472 Score = 305 bits (780), Expect = 1e-80 Identities = 164/429 (38%), Positives = 224/429 (52%), Gaps = 4/429 (0%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 A +PI + GM PGG+ SP +LW + E + +SPFP DRGW V+ L Sbjct: 1058 AQEPIAVVGMGCRFPGGVGSPEALWRLVVEGVDAVSPFPGDRGWDVEGLYDPEPGVAGKS 1117 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 GGFL A FD FFGIS REA+ + PQQR+ + +W+A+E +GI+P S G+ G Sbjct: 1118 YVREGGFLHDAAEFDAEFFGISPREAVAMDPQQRLLLETSWEAIERAGIDPHSLHGSRTG 1177 Query: 129 CFVGMSPMEYGPR-ASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 + G+ P EYGPR A A+ G+ + + R++++LGL GP+++VDT Sbjct: 1178 VYAGVMPQEYGPRLAEGAEGSDGYLLTGTSGSVVSGRVAYTLGLEGPAVTVDTACSSSLV 1237 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R EC+ ALAG V VM PG F EF+R L+ DG C+A++D A GT W E Sbjct: 1238 ALHLAVQALRGGECDMALAGGVTVMAGPGMFVEFSRQRGLAADGRCKAFADGADGTAWAE 1297 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 GAG+VLV N +G + P +QE+VIR+ L A + Sbjct: 1298 GAGVVLVERLSDARRLGHPVLAVVCGSAVNQDGASNGLTAPSGPSQERVIRQALGNARLT 1357 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYGA---AGSEALLGSIKSNAGHSQXXXXXXXX 364 +V ++E HGT T GDP+E AL TYG G LGS+KSN GH+Q Sbjct: 1358 VADVDVVEAHGTGTRLGDPIEAQALLGTYGRDRDGGRPVWLGSLKSNIGHAQAAAGVAGV 1417 Query: 365 XXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGA 424 ++G +P TL D P++ VDW G+ L T+ EW R AVS+FG G Sbjct: 1418 IKMVLAMRYGWLPRTLHVDEPSRHVDWSAGGVWLLTEAREWPGVDRPRRAAVSAFGVSGT 1477 Query: 425 NAHAIISMP 433 NAH I+ P Sbjct: 1478 NAHLILEAP 1486 Score = 303 bits (776), Expect = 3e-80 Identities = 165/429 (38%), Positives = 225/429 (52%), Gaps = 4/429 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+VI GMA PGG +P +LW + E R+++ P DRGW +D + Sbjct: 2576 DPVVIVGMACRFPGGAGTPEALWKLVTEERDVIGAAPTDRGWDLDSVYDPEPGVAGKTYV 2635 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FD FFGIS REA+ + PQQR+ + +W+A+E +GI+P S G+ G + Sbjct: 2636 REGGFLHDAAEFDAEFFGISPREAVAMDPQQRLLLETSWEAIERAGIDPHSLHGSRTGVY 2695 Query: 131 VGMSPMEYGPRASVA-DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 VG++ EY R A + Y G+ + + RIS++LGL GPS+S+DT Sbjct: 2696 VGLTHQEYASRLHEAPEEYEGYLLTGKSASVVSGRISYTLGLEGPSLSIDTACSSSLVAL 2755 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC+ ALAG V VM +PG F EF+R L+ DG C+A++D A GT W EGA Sbjct: 2756 HNAAQALRGGECDMALAGGVTVMAAPGLFVEFSRQRGLAADGRCKAFADGADGTAWAEGA 2815 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G+VLV N +G + P +QE+VIR+ L A + Sbjct: 2816 GVVLVERLSDARRLGHPVLAVVCGSAVNQDGASNGLTAPSGPSQERVIRQALANARLTVA 2875 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGA---AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +V ++E HGT T GDP+E AL TYG A LGS+KSN GH+Q Sbjct: 2876 DVDVVEAHGTGTRLGDPIEAQALLGTYGRDRDAECPVWLGSLKSNIGHAQAAAGVAGVIK 2935 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 ++G +P TL D P++ VDW G+RL T+ EW R AVS+FG G NA Sbjct: 2936 MVLAMRYGWLPRTLHVDEPSRHVDWSAGGVRLLTEAREWPGVDRPRRAAVSAFGVSGTNA 2995 Query: 427 HAIISMPAA 435 H I+ P A Sbjct: 2996 HLILEAPEA 3004 Score = 189 bits (479), Expect = 8e-46 Identities = 122/371 (32%), Positives = 171/371 (46%), Gaps = 9/371 (2%) Query: 76 LDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCFVGMSP 135 L+ FD GFFG++AR+A PQ R+ + + W+ALE++GI PG GT+ G F G++ Sbjct: 86 LEDHAGFDAGFFGMNARQAAATDPQHRLMLELGWEALEDAGIVPGDLTGTDTGVFAGVAS 145 Query: 136 MEYG--PRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXXXXXX 193 +Y R S A G+ L + A R+SH LGL GPS+ VD+ Sbjct: 146 DDYAVLTRRSAVSA-GGYTATGLHRALAANRLSHFLGLRGPSLVVDSAQSASLVAVQLAC 204 Query: 194 XXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGAGMVL 253 +R E A+AG V ++ + + R+ ALS DG C + A G V GEG G V+ Sbjct: 205 ESLRRGETSLAVAGGVNLILTEESTTVMERMGALSPDGRCHTFDARANGYVRGEGGGAVV 264 Query: 254 VXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPVEVGM 313 + N++G G + P AQE V+R+ AG+ V Sbjct: 265 LKPLDAALADGDRVYCVIKGGAVNNDGGGASLTTPDREAQEAVLRQAYRRAGVSTGAVRY 324 Query: 314 IEGHGTATPAGDPVELIALFKTYGAAGSEA-----LLGSIKSNAGHSQXXXXXXXXXXXX 368 +E HGT T AGDPVE AL GA +GS+K+N GH + Sbjct: 325 VELHGTGTRAGDPVEAAALGAVLGAGADSGRSTPLAVGSVKTNVGHLEGAAGIVGLIKAT 384 Query: 369 XXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEW-EPKHGVRYGAVSSFGAGGANAH 427 + G++ P+L P + D LR+ T+ EW E R VSSFG GG N H Sbjct: 385 LCVRKGELVPSLNFSTPNPDIPLDDLRLRVQTERQEWNEEDDRPRVAGVSSFGMGGTNVH 444 Query: 428 AIISMPAAGVG 438 +I+ A G Sbjct: 445 LVIAEAPAAAG 455 >tr|Q9S0R8|Q9S0R8_STRAW Tax_Id=33903 (aveA1)SubName: Full=Type I polyketide synthase AVES 1;[Streptomyces avermitilis] Length = 3972 Score = 304 bits (779), Expect = 1e-80 Identities = 177/442 (40%), Positives = 225/442 (50%), Gaps = 10/442 (2%) Query: 5 GSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLE 64 G+A A DPI I GMA PGG+ SP LW A + + PFP DRGWP + + + Sbjct: 475 GTAAADDPIAIIGMACRFPGGVRSPKDLWELAASGGDAIGPFPTDRGWPTEQRHAQDPTQ 534 Query: 65 GWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAG 124 GGFL A FD GFFGIS REA+ + PQQR+ + +W+A E +GI+P S G Sbjct: 535 PGTFYPQGGGFLHDAAHFDAGFFGISPREALAMDPQQRLLLETSWEAFERAGIDPLSVRG 594 Query: 125 TEGGCFVGMSPMEYGPRASVADA-----YSGHRIASLGQLGGAARISHSLGLIGPSISVD 179 + G F G +YGPR A + GH + + RI++S GL GP+I+VD Sbjct: 595 SRTGVFAGALSFDYGPRMDTASSEGAADVEGHILTGTTGSVLSGRIAYSFGLEGPAITVD 654 Query: 180 TXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDN 239 T +R EC ALAG V VM + G F EF+R LS DG C+AYS Sbjct: 655 TGCSASLVTLHLACQSLRSGECTLALAGGVSVMSTLGMFIEFSRQRGLSVDGRCKAYSAA 714 Query: 240 ATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRK 299 A GT WGEG GM+LV N +G + P AQE+VIR+ Sbjct: 715 ADGTGWGEGVGMLLVERLSDAVRLGHRVLAVVRGSAVNQDGASNGLTAPNGPAQERVIRQ 774 Query: 300 TLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG-AAGSEAL-LGSIKSNAGHSQX 357 L AG+ +V ++EGHGT T GDP+E AL TYG AG L LGS+KSN GH+ Sbjct: 775 ALANAGLSVADVDVVEGHGTGTTLGDPIEAQALLATYGQRAGDRPLWLGSLKSNIGHTMA 834 Query: 358 XXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEW--EPKHGVRYGA 415 + G +P TL D P+ VDW +RL T+ W + +R Sbjct: 835 AAGVGGVIKMVMALREGVLPRTLHVDKPSPQVDWSAGAVRLLTEAVPWPGDAAGRLRRAG 894 Query: 416 VSSFGAGGANAHAII-SMPAAG 436 VSSFG GG NAH I+ PAAG Sbjct: 895 VSSFGIGGTNAHVILEEAPAAG 916 Score = 285 bits (729), Expect = 8e-75 Identities = 166/435 (38%), Positives = 218/435 (50%), Gaps = 7/435 (1%) Query: 2 STNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVS 61 + A +PI I GMA PGG+ S W ++ ++ + FP DRGW +D L Sbjct: 2077 AVTAEASVTEPIAIVGMACRFPGGVTSADDFWDLISSEQDAIGGFPTDRGWDLDTLYDPD 2136 Query: 62 DLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGS 121 +GGFL A FD FFGIS REA+ + PQQR+ + AW+ +E++GINP + Sbjct: 2137 PDHPGTCYTRNGGFLYDAGHFDAEFFGISPREALAMDPQQRLLLETAWETIEHAGINPHT 2196 Query: 122 TAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGG--AARISHSLGLIGPSISVD 179 GT G F G + +Y R A S A G G + RIS++ G GP++SVD Sbjct: 2197 LHGTPTGVFTGTNGQDYALRVHNA-GQSTDGFALTGTAGSVISGRISYTFGFEGPAVSVD 2255 Query: 180 TXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDN 239 T +R EC ALAG V VM SPGAF EF+R L+ DGHC+A+S Sbjct: 2256 TACSSSLVALHLACQALRAGECSMALAGGVTVMSSPGAFVEFSRQRGLAADGHCKAFSAA 2315 Query: 240 ATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRK 299 A GT WGEG GM+LV N +G + P +Q++VIR+ Sbjct: 2316 ADGTGWGEGVGMLLVERLSDAHRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQ 2375 Query: 300 TLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG--AAGSEAL-LGSIKSNAGHSQ 356 L AG+ +V +E HGT T GDP+E AL TYG AG L LGS+KSN GH+Q Sbjct: 2376 ALANAGLSAGDVDAVEAHGTGTTLGDPIEAQALLATYGQDRAGEGPLWLGSVKSNVGHTQ 2435 Query: 357 XXXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHG-VRYGA 415 +HG +P TL D P+ VDW ++L T+ W G +R Sbjct: 2436 AAAGVAGVIKMVMALRHGLLPRTLHVDEPSPHVDWSAGAVQLLTETVPWPGGEGRLRRAG 2495 Query: 416 VSSFGAGGANAHAII 430 VSSFG G NAH I+ Sbjct: 2496 VSSFGVSGTNAHVIL 2510 >tr|A8LUX2|A8LUX2_SALAI Tax_Id=391037 SubName: Full=Beta-ketoacyl synthase;[Salinispora arenicola] Length = 7279 Score = 304 bits (779), Expect = 1e-80 Identities = 170/440 (38%), Positives = 227/440 (51%), Gaps = 4/440 (0%) Query: 1 MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV 60 + T A A DPIVI GMA PGG+ SP LW + + + FP DRGW VD L Sbjct: 2656 LPTVAVAPADDPIVIVGMACSYPGGVRSPDDLWRLVDAGVDAIGEFPGDRGWDVDALFDP 2715 Query: 61 SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG 120 + + GGFL A FDP FF IS REA+ + PQ R+ + AW+A+E++GI+P Sbjct: 2716 DPEQVGKSLTREGGFLYDAADFDPEFFSISPREALAIDPQHRLLLEAAWEAMEHAGIDPQ 2775 Query: 121 STAGTEGGCFVGMSPMEYGPRASVA-DAYSGHRIASLGQLGGAARISHSLGLIGPSISVD 179 G+ G F G+ +Y R A D + G+ + + R+S++ G GP+++VD Sbjct: 2776 DLRGSRTGVFTGLMYHDYVSRMPAAPDGFEGYLLTGNTGSVASGRVSYTYGFEGPAVTVD 2835 Query: 180 TXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDN 239 T +R EC ALAG V VM +P F EF+R LS DG CRAYSD+ Sbjct: 2836 TACSSSLVSLHLAAQALRAGECSLALAGGVTVMSTPHTFVEFSRQRGLSPDGRCRAYSDD 2895 Query: 240 ATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRK 299 A GT WGEG GM+++ N +G + P AQE+VIR+ Sbjct: 2896 AAGTGWGEGVGMLVLERLSHARRNGRRILAIVRGSAVNQDGASNGLTAPNGPAQERVIRQ 2955 Query: 300 TLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG--AAGSEAL-LGSIKSNAGHSQ 356 L AG+ P +V +EGHGT T GDP+E AL TYG G + L LGS+KSN GH+Q Sbjct: 2956 ALAAAGLTPADVDAVEGHGTGTRLGDPIEAGALLSTYGQERTGDQPLWLGSLKSNIGHTQ 3015 Query: 357 XXXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAV 416 +HG++P TL+A+ P+ VDW + L ++ EW R AV Sbjct: 3016 AAAGVGGVIKMVLAMRHGRLPRTLYAEVPSTRVDWQSGAVALLSEAVEWPETGRSRRSAV 3075 Query: 417 SSFGAGGANAHAIISMPAAG 436 SSFG G NAH I+ P G Sbjct: 3076 SSFGISGTNAHVILESPDPG 3095 Score = 300 bits (768), Expect = 2e-79 Identities = 167/431 (38%), Positives = 216/431 (50%), Gaps = 2/431 (0%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 A DPIVI M+ PGG++SP LW + E + + PFPRDRGW VD L Sbjct: 5805 ADDPIVIVAMSCRFPGGVESPEDLWRLVDEGVDAIGPFPRDRGWDVDGLYHPDPDHAGTT 5864 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 G FL GA FD FFGIS REA + PQQR+ + AW+A E +GI+P S G++ G Sbjct: 5865 TVREGSFLAGAGDFDAPFFGISPREAAAMDPQQRLLLETAWEAFERAGIDPASLRGSQAG 5924 Query: 129 CFVGMSPMEYGPRASVA-DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 FVG + EY A D Y+G + RI+++ G GP+++VDT Sbjct: 5925 VFVGSNGQEYATLVQAASDEYAGFGATGATASVMSGRIAYTFGFEGPAVTVDTACSSSLV 5984 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R+ EC ALAG V VM +PG F EF+R LS DG CR+++ A GT WGE Sbjct: 5985 ALHLAVQSLRQGECSLALAGGVTVMATPGLFVEFSRQRGLSADGRCRSFAAGADGTAWGE 6044 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 G G +L+ N +G + P AQ+QVIR+ L AG+ Sbjct: 6045 GVGWLLLERRSDAERRGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQQVIRRALAGAGLS 6104 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXXXX 366 +V ++E HGT T GDP+E AL TYG L LGS+KSN GH+Q Sbjct: 6105 SDQVDVVEAHGTGTRLGDPIEAQALLATYGQGRDRPLWLGSLKSNIGHTQAAAGVAGVIK 6164 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +HG +P TL D PT VDW + L W + R AVSSFG G NA Sbjct: 6165 MVQAMRHGVLPRTLHVDAPTPEVDWSAGAVELLVDSRPWPVRGEPRRAAVSSFGISGTNA 6224 Query: 427 HAIISMPAAGV 437 H I+ A+ V Sbjct: 6225 HVILEEGASPV 6235 Score = 299 bits (765), Expect = 5e-79 Identities = 168/434 (38%), Positives = 218/434 (50%), Gaps = 5/434 (1%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 +A +PI + GM+ PG + SP W L + R+ ++ FP DRGW +D L Sbjct: 986 AAAPDEPIAVVGMSCRLPGEVTSPEEFWELLRDGRDAITEFPTDRGWDLDKLYHPEPGTA 1045 Query: 66 WGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGT 125 +GGF+D A FD FFGIS REA + PQQR+ AW+ALE+ GI+P G+ Sbjct: 1046 GRTYARAGGFVDAAG-FDAAFFGISPREAAAMDPQQRLLAETAWEALESGGIHPDGLRGS 1104 Query: 126 EGGCFVGMSPMEYGPR-ASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 G FVG++ EYGPR A + GH + G + RIS+ GL GP+I+VDT Sbjct: 1105 RTGVFVGVTAQEYGPRLAEAPEGAEGHTLTGTGVSVASGRISYLFGLQGPAITVDTACSS 1164 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R+ EC A AG VM SPG F EFA+ L+ DG C+++ A GT Sbjct: 1165 SLVALHLAVGSLRQGECSLAFAGGATVMSSPGMFVEFAQQRGLAPDGRCKSFGAAADGTG 1224 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 W EG GM+++ N +G + P AQ+QVIR+ L A Sbjct: 1225 WSEGVGMLVLERLSDAQVRGHQVLAVVRGTAVNSDGASNGLTAPNGLAQQQVIRQALAAA 1284 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYGA---AGSEALLGSIKSNAGHSQXXXXX 361 G+D +V +E HGT T GDP+E AL TYGA A LLGS+KSN GH+Q Sbjct: 1285 GLDAGDVDAVEAHGTGTRLGDPIEATALQATYGAGHTAERPLLLGSVKSNIGHTQAAAGV 1344 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +HG +PPTL A P+ VDW L L TK W AVSSFG Sbjct: 1345 VGVIKMVLALRHGVLPPTLHAGEPSPEVDWSPGTLHLLTKAAPWPVAGRPARAAVSSFGI 1404 Query: 422 GGANAHAIISMPAA 435 G NAHAI+ A Sbjct: 1405 SGTNAHAILEAAPA 1418 Score = 283 bits (724), Expect = 3e-74 Identities = 157/429 (36%), Positives = 211/429 (49%), Gaps = 2/429 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DPIVI M+ PGG+ SP LW + E + + PFP DRGW + L Sbjct: 4386 DPIVIVAMSCRFPGGVASPEDLWRLVDEGVDAIGPFPADRGWDLAGLYDPDPDHPGTSYT 4445 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 +GGFL A FDPGFFG+S REA + PQ R+ + AW+A E +G++ + G++ G F Sbjct: 4446 RAGGFLTDAALFDPGFFGMSPREATAMDPQHRLLLETAWEAFERAGVDVATLHGSDTGVF 4505 Query: 131 VGMSPMEYGPR-ASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 G+ +Y S + G + R+S++ GL GP+++VDT Sbjct: 4506 AGLMLHDYERAPGSAPENLEGQLAVGSAPSVASGRVSYTFGLQGPAVTVDTACSSSLVAL 4565 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R+ EC ALAG V VM +PG F EF+R LS DG CR+++ A GT WGEG Sbjct: 4566 HLAVQSLRQGECSLALAGGVTVMATPGLFVEFSRQRGLSADGRCRSFAAGADGTAWGEGV 4625 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G +L+ N +G + P AQ+QVIR+ L AG+ Sbjct: 4626 GWLLLERRSDAERRGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQQVIRRALAGAGLSSD 4685 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXXXXXX 368 +V ++E HGT T GDP+E AL TYG L LGS+KSN GH+Q Sbjct: 4686 QVDVVEAHGTGTRLGDPIEAQALLATYGQGRDRPLWLGSLKSNIGHTQAAAGVAGVIKMV 4745 Query: 369 XXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAHA 428 +HG +P TL D PT VDW + L W + R AVSSFG G NAH Sbjct: 4746 QAMRHGVLPRTLHVDAPTPEVDWSAGAVELLVDSRPWPVRGEPRRAAVSSFGISGTNAHV 4805 Query: 429 IISMPAAGV 437 I+ A+ V Sbjct: 4806 ILEEGASPV 4814 Score = 218 bits (556), Expect = 9e-55 Identities = 140/426 (32%), Positives = 201/426 (47%), Gaps = 15/426 (3%) Query: 12 PIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVCD 71 PI + G++ PG +D PA+ W L R ++ P DR W D G Sbjct: 14 PIAVVGLSCRLPG-VDGPATFWRLLTGGRSTITEVPVDR-W---------DASGDQTGAR 62 Query: 72 SGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCFV 131 G FLD FDPGFFGIS REA + PQQR+A+ ++W+ALE++GI P + AG+ G F+ Sbjct: 63 WGSFLDRVDEFDPGFFGISPREAAAIDPQQRLALELSWEALEHAGIVPDAVAGSRVGVFL 122 Query: 132 GMSPMEYGPRASV--ADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 +Y + D + H A + + A RIS+ L GPS+++DT Sbjct: 123 AAMHDDYALLTHLHHGDQPTQHTFAGVQRSLLANRISYLLRARGPSLTIDTGQSSSLVAV 182 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R E + A+AG V ++ +P + R ALS DG CR + A G V GEG Sbjct: 183 HLAAESLRSGETDLAIAGGVNLILAPESSRTAERFGALSPDGRCRTFDAAANGFVRGEGG 242 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G V++ N++G G + P AQ +V+R + +G Sbjct: 243 GAVVLKRHEDALAAGDTVLALIAGTAVNNDGGGAGLTAPSQEAQREVLRLAHQRSGTPAT 302 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGAA--GSEALLGSIKSNAGHSQXXXXXXXXXXX 367 +G +E HGT TP GDPVE AL GAA GS +GS+K+ GH + Sbjct: 303 CIGYVELHGTGTPVGDPVEAAALGAALGAARPGSPLPVGSVKTVVGHLEAAAGVIGLLKT 362 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 +H ++PP+L D P + D LR+ T+ W R VS+FG GG N H Sbjct: 363 VLALRHRELPPSLGFDTPHPDIPLDQLNLRVVTETEPWLHTGLPRAAGVSAFGMGGTNCH 422 Query: 428 AIISMP 433 +++ P Sbjct: 423 IVLTEP 428 >tr|Q1MX81|Q1MX81_9ACTO Tax_Id=299254 (tmnA1)SubName: Full=Type I polyketide synthase;[Streptomyces sp. NRRL 11266] Length = 4872 Score = 304 bits (779), Expect = 1e-80 Identities = 166/437 (37%), Positives = 226/437 (51%), Gaps = 5/437 (1%) Query: 2 STNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVS 61 +T + A DP+V+ GMA PGG+ SPA LW + RE +S FP DRGW D L Sbjct: 1040 TTATAVDADDPVVVVGMACRYPGGVTSPAELWEMVWSGREGISEFPVDRGWGAD-LFDAD 1098 Query: 62 DLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGS 121 + GGFL A FD FFG+S REA+ + PQQR+ + +W+A E +GI+P S Sbjct: 1099 PGKSGKSYARHGGFLHDAGEFDAEFFGVSPREALAMDPQQRLVLEASWEACERAGIDPDS 1158 Query: 122 TAGTEGGCFVGMSPMEYGPR-ASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDT 180 G+ G ++G + EYGPR A D + GH + + R++++ GL GP++++DT Sbjct: 1159 LRGSRTGVYIGATAQEYGPRLADGHDGHDGHLLTGTTVSVLSGRVAYAFGLEGPAVTIDT 1218 Query: 181 XXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA 240 +R EC+ AL G V VMGSPG F EF+R LS DG C+A+++ A Sbjct: 1219 ACSSSLVAVHLAAQALRNGECDRALVGGVTVMGSPGMFLEFSRQRGLSPDGRCKAFAEGA 1278 Query: 241 TGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKT 300 GT W EG G++LV N +G + P +Q++VI++ Sbjct: 1279 DGTGWAEGVGLLLVERLSEARRQGHEVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIQQA 1338 Query: 301 LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQX 357 L AG+ +V +E HGT T GDP+E AL TYG +A LGS+KSN GH+Q Sbjct: 1339 LASAGLSAGQVDAVEAHGTGTKLGDPIEAQALLATYGREHSAEQPLWLGSLKSNIGHTQA 1398 Query: 358 XXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVS 417 + G +P TL D PT VDWD + L T+ EW R AVS Sbjct: 1399 AAGVAGVIKMVEAMRRGGLPRTLHVDQPTTHVDWDAGAVALLTEAREWPETGEPRRAAVS 1458 Query: 418 SFGAGGANAHAIISMPA 434 SFG G NAH I+ PA Sbjct: 1459 SFGISGTNAHVILEAPA 1475 Score = 290 bits (743), Expect = 2e-76 Identities = 162/431 (37%), Positives = 220/431 (51%), Gaps = 7/431 (1%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 A DP+V+ GMA PGG+ SPA LW + RE +S FP DRGW D L + Sbjct: 2808 ADDPVVVVGMACRYPGGVTSPAELWELVWSGREGISEFPVDRGWGAD-LFDADPGKSGKS 2866 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 GGFL A FD FFG+S REA+ + PQQR+ + +W+A E +GI+P S G+ G Sbjct: 2867 YARHGGFLHDAGEFDAEFFGVSPREALAMDPQQRLVLEASWEACERAGIDPDSLRGSRTG 2926 Query: 129 CFVGMSPMEYGPRASVADAYSGHRIASLGQLGG--AARISHSLGLIGPSISVDTXXXXXX 186 +VG+ +Y PR S + A G L + R++++ GL GP++++DT Sbjct: 2927 VYVGVMYHDYAPRMST-ERQEIEGYALTGNLSSVLSGRVAYAFGLEGPAMTIDTACSSSL 2985 Query: 187 XXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWG 246 +R EC+ AL G V VM +P F EF+R LS DG C+A+++ A GT W Sbjct: 2986 VALHLAAQAMRNGECDRALVGGVTVMATPNTFVEFSRQRGLSPDGRCKAFAEGADGTGWS 3045 Query: 247 EGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGI 306 EG G++LV N +G + P +Q++VI++ L AG+ Sbjct: 3046 EGVGLLLVERLSEARRQGHEVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIQQALASAGL 3105 Query: 307 DPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE---ALLGSIKSNAGHSQXXXXXXX 363 +V +EGHGT T GDP+E AL TYG S+ LGSIKSN GH+Q Sbjct: 3106 SAGQVDAVEGHGTGTKLGDPIEAEALLATYGREHSDERPLWLGSIKSNLGHTQAAAGVAG 3165 Query: 364 XXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGG 423 + G +P TL D P+ VDWD + L T+ EW R AVSSFG G Sbjct: 3166 VIKMVEAMRRGALPQTLHVDEPSTHVDWDAGAVALLTEAREWPETGEPRRAAVSSFGISG 3225 Query: 424 ANAHAIISMPA 434 NAH I+ PA Sbjct: 3226 TNAHVILEQPA 3236 Score = 201 bits (510), Expect = 2e-49 Identities = 136/427 (31%), Positives = 189/427 (44%), Gaps = 13/427 (3%) Query: 12 PIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVCD 71 PI + G A P D+P + W L + R+ ++ P R DL + + G + Sbjct: 20 PIAVVGTACRLPQA-DTPEAFWELLRDGRDAVTGLPDGR----PDLHAPGEAPGRAR--- 71 Query: 72 SGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCFV 131 SG FLD FDP FFGI REA + PQQR+ + +AW+ LE +GI P S AGT G FV Sbjct: 72 SGAFLDHVDLFDPAFFGIGPREAAAMDPQQRLVLELAWETLERTGIVPASLAGTRTGVFV 131 Query: 132 GMSPMEYGPRASVAD--AYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 G +Y A H L + A R+S+ LGL GPS+SVDT Sbjct: 132 GAMADDYARLTQQLGPAAVGQHTATGLHRGIIANRVSYLLGLTGPSMSVDTGQSSSLTAV 191 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 + E + ALAG V + + + ALS DG C + A G V GEG Sbjct: 192 HLACESLLRGEADLALAGGVSLNLTADGYEITEAFGALSPDGRCHTFDARANGYVRGEGG 251 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G+VL+ N++G + P R Q ++R + AG+ P Sbjct: 252 GLVLLKRLSDALDDGDRVLGVILGSAVNNDGTTDTLTTPGARGQTDLLRLACDRAGVAPG 311 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGAAGSEA---LLGSIKSNAGHSQXXXXXXXXXX 366 ++ +E HGT T GDPVE AL + GA +A +GS K+N GH + Sbjct: 312 DIQYVELHGTGTRLGDPVEATALGEALGAGRGDADRLRVGSAKTNVGHLEGAAGITGLIK 371 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 H ++P +L + GLR+ + W VSSFG GGANA Sbjct: 372 TLLSLHHRELPRSLHFRAANPAIPLAGLGLRVQEEHGPWPDGDRRLIAGVSSFGMGGANA 431 Query: 427 HAIISMP 433 H +++ P Sbjct: 432 HVVVAEP 438 >tr|O54666|O54666_AMYMD Tax_Id=33910 (rifA)SubName: Full=RifA; SubName: Full=Rifamycin polyketide synthase, type 1;[Amycolatopsis mediterranei] Length = 4735 Score = 304 bits (779), Expect = 1e-80 Identities = 164/426 (38%), Positives = 222/426 (52%), Gaps = 2/426 (0%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 +A +PI I GMA PGG+ SP LW +AE + +S FP DRGW +D L+ Sbjct: 627 AADPGEPIAIVGMACRLPGGVASPEDLWRLVAERVDAVSEFPGDRGWDLDSLIDPDRERA 686 Query: 66 WGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGT 125 GGFL A FD GFFGIS REA+ + PQQR+ + +W+ALEN+G++P + GT Sbjct: 687 GTSYVGQGGFLHDAGEFDAGFFGISPREAVAMDPQQRLLLETSWEALENAGVDPIALKGT 746 Query: 126 EGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXX 185 + G F G+ YG A VA G + + R+S+ LGL GP+++VDT Sbjct: 747 DTGVFSGLMGQGYGSGA-VAPELEGFVTTGVASSVASGRVSYVLGLEGPAVTVDTACSSS 805 Query: 186 XXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVW 245 +R+ EC ALAG V VM +PG+F EF+R AL+ DG C+A++ A GT W Sbjct: 806 LVAMHLAAQALRQGECSMALAGGVTVMATPGSFVEFSRQRALAPDGRCKAFAAAADGTGW 865 Query: 246 GEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAG 305 EG G+V++ N +G + P +Q++VIR+ L AG Sbjct: 866 SEGVGVVVLERLSVARERGHRILAVLRGSAVNQDGASNGLTAPNGLSQQRVIRRALAAAG 925 Query: 306 IDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXX 364 + P +V ++E HGT T GDP+E AL TYG + L LGS+KSN GH+Q Sbjct: 926 LAPSDVDVVEAHGTGTTLGDPIEAQALLATYGQERKQPLWLGSLKSNIGHAQAAAGVAGV 985 Query: 365 XXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGA 424 +H +PPTL D PT VDW + L T+ W R VSSFG G Sbjct: 986 IKMVQALRHETLPPTLHVDKPTLEVDWSAGAIELLTEARAWPRNGRPRRAGVSSFGVSGT 1045 Query: 425 NAHAII 430 NAH I+ Sbjct: 1046 NAHLIL 1051 Score = 299 bits (765), Expect = 5e-79 Identities = 161/422 (38%), Positives = 218/422 (51%), Gaps = 2/422 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GM+ PGG DSP LW +AE R+ +S FP DRGW +D L Sbjct: 3172 EPIAIVGMSTRLPGGADSPEELWKLVAEGRDAVSGFPVDRGWDLDGLYHPDPAHAGTSYT 3231 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 SGGFL A FD G FGIS REA+ + PQQR+ + +W+ALE +G++P S G++ G F Sbjct: 3232 RSGGFLHDAAQFDAGLFGISPREALAMDPQQRLLLETSWEALERAGVDPLSARGSDVGVF 3291 Query: 131 VGMSPMEYGPR-ASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 G+ +Y R V + G+ + + R+++ G GP+++VDT Sbjct: 3292 TGIVHHDYVTRLREVPEDVQGYTMTGTASSVASGRVAYVFGFEGPAVTVDTACSSSLVAM 3351 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R+ EC ALAG VM SP AF EF+R LS DG C+AY++ A GT W EG Sbjct: 3352 HLAAQALRQGECSMALAGGATVMASPDAFLEFSRQRGLSADGRCKAYAEGADGTGWAEGV 3411 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G+V++ N +G + P +Q++VIR L AG+ P Sbjct: 3412 GVVVLERLSVARERGHRVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRGALASAGLAPS 3471 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXXXXXX 368 +V ++EGHGT T GDP+E+ AL TYG + L LGS+KSN GH+Q Sbjct: 3472 DVDVVEGHGTGTALGDPIEVQALLATYGQEREQPLWLGSLKSNLGHTQAAAGVVGVIKMI 3531 Query: 369 XXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAHA 428 +HG +P TL D T VDW + + T+ EW R VSSFGA G NAH Sbjct: 3532 MAMRHGVMPATLHVDERTSQVDWSAGAIEVLTEAREWPRTGRPRRAGVSSFGASGTNAHL 3591 Query: 429 II 430 II Sbjct: 3592 II 3593 Score = 285 bits (729), Expect = 8e-75 Identities = 158/435 (36%), Positives = 218/435 (50%), Gaps = 3/435 (0%) Query: 5 GSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVS-DL 63 G+A A +PI I MA PGG+ SP LW +A+ + ++ FP DRGW D L D Sbjct: 2189 GTAAAEEPIAIVAMACRFPGGVHSPEDLWRLVADGADAVTEFPADRGWDTDRLYHEDPDH 2248 Query: 64 EGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 EG V G FLD A FD FFGIS EA+ + PQQR+ + +W+ E + I+P + A Sbjct: 2249 EGTTYV-RHGAFLDDAAGFDAAFFGISPNEALAMDPQQRLLLETSWELFERAAIDPTTLA 2307 Query: 124 GTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXX 183 G + G F G++ +Y R A G R+ + R+++ G+ GP+++VDT Sbjct: 2308 GQDIGVFAGVNSHDYSMRMHRAAGVEGFRLTGGSASVLSGRVAYHFGVEGPAVTVDTACS 2367 Query: 184 XXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGT 243 ++ EC ALAG V VMG+ F EF+R L+ DG C+A++D A GT Sbjct: 2368 SSLVALHMAVQALQRGECSMALAGGVMVMGTVETFVEFSRQRGLAPDGRCKAFADGADGT 2427 Query: 244 VWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEV 303 W EG G++LV N +G + P +Q++VIRK L Sbjct: 2428 GWSEGVGLLLVERLSEAQRRGHQVLAVVRGSAVNSDGASNGLTAPNGPSQQRVIRKALAA 2487 Query: 304 AGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXX 362 AG+ +V +E HGT T GDP+E AL TYG L LGS+KSN GH+Q Sbjct: 2488 AGLSTSDVDAVEAHGTGTTLGDPIEAEALLATYGQNRETPLWLGSVKSNLGHTQAAAGVA 2547 Query: 363 XXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAG 422 +HG +P TL D P+ VDW + L T+ +W R VSSFG G Sbjct: 2548 GVIKMVMAMRHGVLPRTLHVDRPSSYVDWSAGAVELLTEARDWVSNGHPRRAGVSSFGIG 2607 Query: 423 GANAHAIISMPAAGV 437 G NAH ++ AA + Sbjct: 2608 GTNAHVVLEEVAAPI 2622 >tr|B6ZIR3|B6ZIR3_STRPT Tax_Id=58346 (pldAII)SubName: Full=Polyketide synthase;[Streptomyces platensis] Length = 7026 Score = 304 bits (779), Expect = 1e-80 Identities = 165/424 (38%), Positives = 220/424 (51%), Gaps = 4/424 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GMA PGG++SP LW +A+ R+ +S FP DRGW V+ L Sbjct: 3662 EPIAIVGMACRYPGGVESPEDLWQLVADGRDAISDFPADRGWNVESLYHPDPDHPGTSYT 3721 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 +GGFL A FDP FFGIS REA+ PQQR+ + +W+A+E +GINP + GT G F Sbjct: 3722 RAGGFLHDAADFDPEFFGISPREALATDPQQRLLLETSWEAMERAGINPSTLKGTPTGVF 3781 Query: 131 VGMSPMEYGPRAS-VADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 +G+ +YG A+ + GH + + R+S++ GL GP+++VDT Sbjct: 3782 LGVMYNDYGTAMQQAAEVFEGHMASGSAGSVASGRVSYTFGLEGPAVTVDTACSSSLVAL 3841 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R EC ALAG V VM +P F EF+R L+ DG C+A++D A GT WGEG Sbjct: 3842 HLAAQALRNGECTLALAGGVAVMSTPATFVEFSRQRGLAADGRCKAFADAADGTGWGEGV 3901 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G++LV N +G + P +Q++VI++ L AG+ Sbjct: 3902 GVLLVERLSDARRNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIQQALANAGLAGA 3961 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGAAGS---EALLGSIKSNAGHSQXXXXXXXXXX 366 +V +E HGT T GDP+E AL TYG A S LGS+KSN GH+Q Sbjct: 3962 DVDAVEAHGTGTRLGDPIEAQALIATYGQARSADRPLWLGSLKSNIGHTQAAAGVAGVIK 4021 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QHG +PPTL D PT VDW + L T+ W R AVSSFG G NA Sbjct: 4022 MVQAMQHGTLPPTLHIDQPTGQVDWATGAVELLTEAVPWPDSDRPRRVAVSSFGVSGTNA 4081 Query: 427 HAII 430 H II Sbjct: 4082 HVII 4085 Score = 283 bits (725), Expect = 2e-74 Identities = 160/433 (36%), Positives = 217/433 (50%), Gaps = 6/433 (1%) Query: 7 AGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGW 66 A A+PI I G A PGG+ SP LW +AE + +S FP DRGW ++DL Sbjct: 34 AAEAEPIAIVGTACRYPGGVRSPEDLWRLVAEGQHAISSFPTDRGWDLEDLYDPDPDRPG 93 Query: 67 GQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTE 126 GGFLDGA FD FFGIS REA+ + PQQR+ + W+ E +GI+P S G+ Sbjct: 94 KSYARDGGFLDGAAQFDAAFFGISPREALAMDPQQRLLLETTWEVFERAGIDPTSLRGSR 153 Query: 127 GGCFVGMSPMEY--GPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 G F G+S +Y G R S A+ GH + + R++++ GL GP+++VDT Sbjct: 154 TGVFAGISHQDYAAGQRPS-AEVSEGHLMTGTAVSVVSGRVAYAFGLEGPAMTVDTACSS 212 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R EC A+AG V VM +PGAF F+R L+ DG C+A+S +A GT Sbjct: 213 SLVALHLAAQALRNGECTLAVAGGVTVMATPGAFTRFSRERGLAPDGRCKAFSSDADGTG 272 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 + EG G++LV N +G + P +Q++VI++ L A Sbjct: 273 FSEGVGVLLVERLSDARRNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIQQALANA 332 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGS---EALLGSIKSNAGHSQXXXXX 361 G+ +V +E HGT T GDP+E AL TYG A S LGS+KSN GH+Q Sbjct: 333 GLAGADVDAVEAHGTGTRLGDPIEAQALIATYGQARSADRPLWLGSLKSNIGHTQAAAGV 392 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 HG +P TL + P+ VDW + L T+ W R +SSFG Sbjct: 393 AGVIKMIQAMGHGTLPRTLHVNQPSPQVDWAAGAVELLTEAMPWPEGDRPRRAGISSFGI 452 Query: 422 GGANAHAIISMPA 434 G NAH II A Sbjct: 453 SGTNAHVIIEQGA 465 Score = 275 bits (703), Expect = 8e-72 Identities = 152/429 (35%), Positives = 212/429 (49%), Gaps = 4/429 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I M+ PGG+ +P LW +AE R+ ++ FP DRGW +D L Sbjct: 1841 EPIAIVAMSCRYPGGVCTPEDLWRLVAEGRDTITDFPDDRGWDIDALYDPDPGHPGTSYT 1900 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FDP FF IS REA+ + PQQR+ + + W+ E + I+P + G++ G F Sbjct: 1901 RRGGFLSDAAGFDPAFFRISPREALAMDPQQRLLLEMTWEMFERALIDPTTLKGSQAGVF 1960 Query: 131 VGMSPMEYGPRAS-VADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 +G + YG R + G ++ + RIS++ GL GP+++VDT Sbjct: 1961 IGTAGPGYGGRIHHESQGVEGQQLFGGSAAVTSGRISYTFGLEGPAMTVDTMCSSSLVAL 2020 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 +R E ALAG V VM P AF EF+R LS DG C++++D A GT WGEGA Sbjct: 2021 HLAVQSLRNGESSMALAGGVTVMSRPAAFTEFSRQRGLSPDGRCKSFADAADGTGWGEGA 2080 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G++L+ N +G + P +Q++VIR+ L A + P Sbjct: 2081 GVLLLERLSDARRNGHPVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALANASLSPA 2140 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXXXXXXX 366 +V +E HGT TP GDP+E AL TYG A LGS+KSN H+Q Sbjct: 2141 DVDAVEAHGTGTPLGDPIEAQALIATYGQDRPADRPLRLGSVKSNIAHAQAAAAVGGVIK 2200 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +HG +P TL + P++ VDW + L T+ W R VS+FG G NA Sbjct: 2201 MVQAIRHGLLPKTLHVEQPSRHVDWSAGSVELLTEAMPWPETDQPRRAGVSAFGGSGTNA 2260 Query: 427 HAIISMPAA 435 H II A Sbjct: 2261 HMIIEQAPA 2269 Score = 271 bits (692), Expect = 2e-70 Identities = 154/432 (35%), Positives = 210/432 (48%), Gaps = 9/432 (2%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I M+ PGG+ SP LW L + ++ FP DR W VD L Sbjct: 5223 EPIAIVSMSCRFPGGVSSPEELWQLLLAGEDTITGFPDDRDWDVDALYDPDPDHPGTTYS 5282 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 SG FL A FD FGIS REA+ + PQQR+ + AW+ E +GI+P S G+ G F Sbjct: 5283 RSGAFLSDAAGFDATLFGISPREALAMDPQQRLLLETAWEVFERAGIDPTSVRGSRAGVF 5342 Query: 131 VGMSPMEYG---PRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 VG + +Y P+ + G+ +A + R+S++ GL GP+++VDT Sbjct: 5343 VGTNGQDYARHVPQEPIG--VEGYLLAGNAASVISGRLSYTFGLEGPAVTVDTACSSSLV 5400 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R EC ALAG V VM +P AF EF+R L+ DG C+A++D A GT WGE Sbjct: 5401 ALHLAVQALRNGECSIALAGGVSVMSTPAAFVEFSRQRGLAADGRCKAFADAADGTGWGE 5460 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 G G++LV N +G + P +Q++VIR+ L A + Sbjct: 5461 GVGVLLVERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALVDAALT 5520 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXXXXX 364 ++ +E HGT T GDP+E AL TYG A LGS+KSN H+Q Sbjct: 5521 GSDIDAVEAHGTGTRLGDPIEAQALIATYGQDRPANRPLWLGSVKSNIAHTQAAAGVAGV 5580 Query: 365 XXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGA 424 +HG +P TL D PT VDW+ + L T+ W R +SSFG G Sbjct: 5581 IKMVQAIRHGVLPKTLHVDRPTSHVDWEAGAVELLTEAMPWPETDRPRRAGISSFGVSGT 5640 Query: 425 NAHAIISM-PAA 435 NAH I+ PAA Sbjct: 5641 NAHTIVEQAPAA 5652 >tr|A1YAN0|A1YAN0_AMYOR Tax_Id=31958 SubName: Full=Polyketide synthase type I;[Amycolatopsis orientalis] Length = 5099 Score = 304 bits (778), Expect = 2e-80 Identities = 164/426 (38%), Positives = 227/426 (53%), Gaps = 8/426 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GMA PGG+ SP LW +AE R+ +S FP DRGW + L + + C Sbjct: 34 EPIAIIGMACRFPGGVRSPEDLWELVAEGRDGISGFPADRGWDLSALYDPTGEKPGTSYC 93 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFLDGA FDP FFGIS REA+ + PQQR+ + ++W+ E +GI+PGS G+ G F Sbjct: 94 REGGFLDGAGEFDPAFFGISPREALAMDPQQRLLLEISWETFERAGIDPGSLRGSRTGVF 153 Query: 131 VGMSPMEYGPR-ASVADAYSGHRIASLGQLGG--AARISHSLGLIGPSISVDTXXXXXXX 187 G+ +Y R A++ + G+ G G + R++++ GL GP++++DT Sbjct: 154 AGVMYHDYVSRLAAIPEELEGY--LGTGNSGSVVSGRVAYTFGLEGPAVTIDTACSSSLV 211 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R+ EC ALAG V VM +P F +F+R L+ DG C++YSD A GT W E Sbjct: 212 ALHLAAQALRQGECSMALAGGVAVMSTPDTFVDFSRQRGLAADGRCKSYSDGADGTSWAE 271 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 G GM+LV N +G + VP +Q++VIR+ LE A + Sbjct: 272 GVGMLLVEKLSDARRLGHEVLAVVSGSAVNQDGASSGLSVPNGPSQQRVIRQALENARLS 331 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXXXXX 364 ++ ++EGHGT T GDP+E AL TYG +A LGS+KSN GHSQ Sbjct: 332 AGQIDVVEGHGTGTTLGDPIEAQALLATYGREKSADRPLWLGSLKSNIGHSQSAAGVGGV 391 Query: 365 XXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGA 424 +HG +P TL A++P+ VDW + L T+ W R VSSFG G Sbjct: 392 IKMVQAIRHGILPRTLHAEDPSSKVDWSAGAVELLTEARGWPETGQPRRAGVSSFGVSGT 451 Query: 425 NAHAII 430 NAH II Sbjct: 452 NAHTII 457 Score = 291 bits (744), Expect = 1e-76 Identities = 160/434 (36%), Positives = 222/434 (51%), Gaps = 4/434 (0%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 +A +PI I GMA PGG+ SP LW ++E R+ ++PFP DRGW V+ L Sbjct: 3312 TAPVDEPIAIVGMACRFPGGVRSPEDLWRLVSEGRDGITPFPADRGWDVEGLYDPEASRP 3371 Query: 66 WGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGT 125 GGFL A FDPGFFGIS REA+ + PQQR+ + +W+A E +GI+P + G+ Sbjct: 3372 GTSCTRYGGFLHDAGDFDPGFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGS 3431 Query: 126 EGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGG--AARISHSLGLIGPSISVDTXXX 183 G F G +Y R + A + + G G + R++++ GL GP++S+DT Sbjct: 3432 ATGVFAGAMYHDYVSRLTEIPADLEGYLGT-GNSGSVISGRLAYAFGLEGPAVSIDTACS 3490 Query: 184 XXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGT 243 +R+ EC ALAG V VM +P F EF+R ++ DG +A+S+ A GT Sbjct: 3491 SSLVAMHLAAQALRQGECGLALAGGVAVMSTPDTFIEFSRQRGMAPDGRIKAFSETADGT 3550 Query: 244 VWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEV 303 WGEG GM+L+ N +G + P +Q++VIR+ L Sbjct: 3551 AWGEGVGMLLLERLSDARRNGHRVLAVLRGTAVNQDGASNGLTAPNGPSQQRVIRQALAQ 3610 Query: 304 AGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXX 362 AG+ P +V +E HGT T GDP+E AL TYG E L LGS+KSN GH+Q Sbjct: 3611 AGLRPSDVDAVEAHGTGTTLGDPIEAQALLATYGQDREEPLWLGSVKSNLGHTQAAAGVA 3670 Query: 363 XXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAG 422 +HG +P TL D P+ VDW + L T+ +W R VSSFG Sbjct: 3671 SVIKMVEAMRHGVLPRTLHVDEPSSHVDWTEGAVSLLTETRDWPDTGRPRRAGVSSFGIS 3730 Query: 423 GANAHAIISMPAAG 436 G NAH ++ AG Sbjct: 3731 GTNAHVVLEADGAG 3744 Score = 277 bits (708), Expect = 2e-72 Identities = 155/424 (36%), Positives = 218/424 (51%), Gaps = 8/424 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GMA PGG+ SP LW +A R+ +S FP +RGW +D+ + Sbjct: 1682 EPIAIIGMACRYPGGVTSPEELWDLVAAGRDGVSEFPVNRGW--EDVYDADPGKVGKSYA 1739 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FD FFGIS REA+ + PQQR+ + +W+ E +GI+P + G++ G F Sbjct: 1740 REGGFLHDAGEFDAAFFGISPREALAMDPQQRLLLETSWEVFERAGIDPHAVRGSKTGVF 1799 Query: 131 VGMSPMEYGPRA-SVADAYSGHRIASLGQLGG--AARISHSLGLIGPSISVDTXXXXXXX 187 G+ +Y R SV + G+ G G + R++++ GL GP++S+DT Sbjct: 1800 AGVMYHDYAARLNSVPEDVEGY--LGTGNSGSVISGRLAYTFGLEGPAVSIDTACSSSLV 1857 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R+ EC A+AG V VM +P F EF+R ++ DG C+++++ A GT WGE Sbjct: 1858 AMHLAGQALRQGECSLAVAGGVTVMATPNTFIEFSRQRGMATDGRCKSFAEAADGTGWGE 1917 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 G GM+L+ N +G + P +Q++VIR+ L AG+ Sbjct: 1918 GVGMLLLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALAQAGLR 1977 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXXXX 366 P +V +E HGT T GDP+E AL TYG E L LGS+KSN GH+Q Sbjct: 1978 PSDVDAVEAHGTGTTLGDPIEAQALLATYGQDREEPLWLGSVKSNLGHTQAAAGVAGVIK 2037 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +HG +P TL D P+ VDW + L T+ EW R VSSFG G NA Sbjct: 2038 MVEAMRHGVLPRTLHVDEPSSHVDWTGGAVSLVTESREWPDTGRPRRAGVSSFGISGTNA 2097 Query: 427 HAII 430 H II Sbjct: 2098 HTII 2101 >tr|Q93HE5|Q93HE5_STRAW Tax_Id=33903 (pks5)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 4498 Score = 302 bits (774), Expect = 5e-80 Identities = 163/426 (38%), Positives = 219/426 (51%), Gaps = 4/426 (0%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 A DPI I GM PGG+ SP +LW + R+ +S PRDRGW +D+L Sbjct: 973 ADDPIAIVGMGCRFPGGVSSPDALWELVRSGRDAVSGLPRDRGWDLDNLFDPDPETSGRT 1032 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 GGFLD FD GFFG+S REA+ + PQQR+ + AW+ LE++GI PGS G++ G Sbjct: 1033 YVRQGGFLDDIAGFDAGFFGVSPREALAMDPQQRLLLETAWETLEDAGIEPGSLRGSDTG 1092 Query: 129 CFVGMSPMEYGPRASVADA-YSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 F+G +YGPR G+ + + R+++ L L GP+++VDT Sbjct: 1093 VFIGAMAGDYGPRLDTPHGGVDGYVLTGTSGSVTSGRLAYFLDLEGPAVTVDTACSSSLV 1152 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 VR EC A+AG V VM SPG EF+R LS DG C+A++++A GT WGE Sbjct: 1153 ALHQAARAVRSGECSLAVAGGVSVMSSPGVLVEFSRQRGLSADGRCKAFAESADGTGWGE 1212 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 GAG+V++ N +G + P +Q++VIR L AG+ Sbjct: 1213 GAGLVVLERLSVARARGHRVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRLALADAGLG 1272 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE---ALLGSIKSNAGHSQXXXXXXXX 364 +V ++E HGT T GDP+E AL TYG SE LGS+KSN GH+ Sbjct: 1273 AGDVDVVEAHGTGTRLGDPIEAQALLATYGKGRSEDRPLWLGSLKSNVGHTMAAAGVGGV 1332 Query: 365 XXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGA 424 + G +P TL D PT VDW G+RL T+ EW + R VSSFG G Sbjct: 1333 IKMVEALRRGVLPATLHVDEPTSHVDWSAGGVRLLTESREWRSEGRPRRAGVSSFGISGT 1392 Query: 425 NAHAII 430 NAH I+ Sbjct: 1393 NAHVIL 1398 Score = 300 bits (767), Expect = 3e-79 Identities = 160/424 (37%), Positives = 219/424 (51%), Gaps = 4/424 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 DP+ + GM PGG+ SP +LW + R+ +S PRDRGW +++L Sbjct: 2758 DPVAVVGMGCRFPGGVSSPDALWELVRSGRDAVSGLPRDRGWDLENLFDPDPGRTGKSYV 2817 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 D G FLD A FD GFFG+S REA+ +HPQQR+ + W+ LE++GI PGS G++ G F Sbjct: 2818 DKGYFLDDAGEFDAGFFGVSPREALAMHPQQRLLLETMWQTLEDAGIEPGSLRGSDTGVF 2877 Query: 131 VGMSPMEYGPRASVADAYS-GHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXX 189 +G +YGP A + G + + R+++ L L GP+++VDT Sbjct: 2878 IGAMSQDYGPPMHEGSAEADGLLLTGTSGSVTSGRLAYFLDLEGPAVTVDTACSSSLVAL 2937 Query: 190 XXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGA 249 VR EC A+AG V VM SPG EF+R LS DG C+A++++A GT WGEGA Sbjct: 2938 HQAARAVRSGECSLAVAGGVSVMSSPGVLVEFSRQRGLSADGRCKAFAESADGTGWGEGA 2997 Query: 250 GMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPV 309 G+V++ N +G + P +Q++VIR L AG+ Sbjct: 2998 GLVVLERLSVARARGHRVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRLALADAGLGAG 3057 Query: 310 EVGMIEGHGTATPAGDPVELIALFKTYGAAGSE---ALLGSIKSNAGHSQXXXXXXXXXX 366 +V ++E HGT T GDP+E AL TYG SE LGS+KSN GH+ Sbjct: 3058 DVDVVEAHGTGTRLGDPIEAQALLATYGKGRSEDRPLWLGSLKSNVGHTMAAAGVGGVIK 3117 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 + G +P TL D PT VDW G+RL T+ EW + R VSSFG G NA Sbjct: 3118 MVEALRRGVLPATLHVDEPTSHVDWSAGGVRLLTESREWRSEGRPRRAGVSSFGISGTNA 3177 Query: 427 HAII 430 H I+ Sbjct: 3178 HVIL 3181 Score = 227 bits (578), Expect = 3e-57 Identities = 145/433 (33%), Positives = 201/433 (46%), Gaps = 20/433 (4%) Query: 1 MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV 60 M T+G D + + G++ PG SP + W LA RE + P DR V Sbjct: 1 MKTSGQ----DVVAVVGLSCRLPGA-SSPEAYWELLAAGREAVGGVPADRAVHV------ 49 Query: 61 SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG 120 G G LDG FD GFFG+S REA + P+QR+ + +AW+ALE++G++P Sbjct: 50 ------GTRVARAGLLDGVADFDAGFFGVSPREAAAMDPRQRLMLELAWEALEHAGVDPS 103 Query: 121 STAGTEGGCFVGMSPMEYGP--RASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISV 178 + G+ G F+G +Y R A A ++SL + A RIS LGL GPS+ V Sbjct: 104 AARGSRAGVFLGAMGDDYAGLVRDQGAGAIDSFTLSSLQRGVLANRISFFLGLSGPSVVV 163 Query: 179 DTXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSD 238 D+ VR E WALAG V ++ SP + + ALS DG C + Sbjct: 164 DSAQSSALVAVHQAYESVRRGESAWALAGGVNLILSPESTATASEFGALSPDGRCYTFDG 223 Query: 239 NATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIR 298 A G V GEGAG+V++ N++G G+ + P QE V+R Sbjct: 224 RANGYVRGEGAGLVVLMPLADAHAYGHDVVCVIRGGAVNNDGGGEQLTTPSRAGQEDVLR 283 Query: 299 KTLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQXX 358 L AG EVG +E HGT TP GD VE AL + ++GS K+N GH++ Sbjct: 284 AALTDAGTRSAEVGYVELHGTGTPVGDRVESAALAAVFADRDRPLVVGSAKTNVGHAEGA 343 Query: 359 XXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSS 418 QHGQ+P +L P + G+ +A +L W P R VSS Sbjct: 344 AGVVGLIKAALAVQHGQVPASLNFAAPADDIPLAELGIEVAAELRAW-PGDEPRVAGVSS 402 Query: 419 FGAGGANAHAIIS 431 FG GG N H +++ Sbjct: 403 FGMGGTNCHLVLA 415 >tr|Q1L0S5|Q1L0S5_STRHY Tax_Id=285527 SubName: Full=NapD;[Streptomyces hygroscopicus subsp. duamyceticus] Length = 1818 Score = 302 bits (773), Expect = 6e-80 Identities = 167/428 (39%), Positives = 218/428 (50%), Gaps = 7/428 (1%) Query: 8 GAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWG 67 G +P+ I GMA PGG+ SP LW ++E RE +S FP DRGW V+ L Sbjct: 28 GTDEPVAIVGMACRLPGGVASPQDLWRLVSEGREGVSGFPEDRGWDVEGLFDADPGRAGK 87 Query: 68 QVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEG 127 D GGFL GA FD GFFGIS REA+ + PQQR+ + V+W+ALE +GI+PG+ G++ Sbjct: 88 SYTDRGGFLPGAGLFDAGFFGISPREALAMDPQQRLLLEVSWEALERAGIDPGTLKGSDV 147 Query: 128 GCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAA--RISHSLGLIGPSISVDTXXXXX 185 G F G+ YG R G + G A R+S+ G GPS+SVDT Sbjct: 148 GVFSGVITQGYGMRGETPPELGG--LVGTGSTASVASGRVSYVFGFEGPSVSVDTACSSS 205 Query: 186 XXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVW 245 +R+ EC ALAG VM +P F EF+R LS DG C+A+S A GT Sbjct: 206 LVAMHLAAQALRQGECSMALAGGATVMANPSTFVEFSRQQGLSSDGRCKAFSAAADGTGL 265 Query: 246 GEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAG 305 EGAG+V++ N +G + P +Q++VIRK L AG Sbjct: 266 AEGAGVVVLELLSEARRNGHQVLAVIRSSAVNQDGASNGLTAPNGPSQQRVIRKALASAG 325 Query: 306 IDPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXXX 362 + +V ++EGHGT T GDP+E AL TYG LGS+KSN GH+Q Sbjct: 326 LSAADVDVVEGHGTGTVLGDPIEAQALLATYGQDREPERPLWLGSLKSNLGHAQAAAGVA 385 Query: 363 XXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAG 422 +HG +P TL AD P+ VDW + L T+ +W R AVSSFG Sbjct: 386 GVIKMVEALRHGVMPATLHADTPSSQVDWSAGAVELLTEARDWPDTGRPRRAAVSSFGVS 445 Query: 423 GANAHAII 430 G NAH I+ Sbjct: 446 GTNAHLIL 453 >tr|Q30CS0|Q30CS0_STRAU Tax_Id=1894 (lipPks3)SubName: Full=LipPks3;[Streptomyces aureofaciens] Length = 3612 Score = 301 bits (772), Expect = 8e-80 Identities = 170/444 (38%), Positives = 226/444 (50%), Gaps = 14/444 (3%) Query: 5 GSAGAA--DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSD 62 G A AA +PI I GMA PGG++SP LW +AE R+ + P DRGW VD L Sbjct: 26 GQAEAARHEPIAIVGMACRYPGGVESPEDLWELVAEGRDAIDVMPGDRGWDVDALYDPDP 85 Query: 63 LEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGST 122 GGFL A FDP FFGIS REA+ + PQQR+ + +W+A E +GI+P + Sbjct: 86 SSTGKTYSREGGFLRNAAEFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATL 145 Query: 123 AGTEGGCFVGMSPMEYGPRASVA------DAYSGHRIASLGQLGGAARISHSLGLIGPSI 176 G+ G F G+ +YG R + Y G+ S G + RI+++LGL GP++ Sbjct: 146 RGSRTGVFAGVMYHDYGSRLGTGTVPEDVEGYVGN--GSAGSIA-TGRIAYTLGLEGPAV 202 Query: 177 SVDTXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAY 236 +VDT +R+ EC ALAG V VM +P F EF+R L+ DG C+A+ Sbjct: 203 TVDTACSSSLVAMHLAIQAIRQGECSMALAGGVTVMATPDTFVEFSRQRGLAPDGRCKAF 262 Query: 237 SDNATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQV 296 A GT W EGAGM+LV N +G + P +Q++V Sbjct: 263 GAGADGTGWAEGAGMLLVERLSDAERLGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRV 322 Query: 297 IRKTLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAG 353 IR+ L AG+ P ++ +EGHGT T GDP+E+ AL TYG A LGS+KSN G Sbjct: 323 IRQALATAGLGPTDIDAVEGHGTGTSLGDPIEVQALQATYGQERPAERPLWLGSLKSNIG 382 Query: 354 HSQXXXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRY 413 H+Q + G +P TL AD P+ +DW +RL T+ W R Sbjct: 383 HAQAAAGVGGVIKMVMALREGVLPRTLHADEPSPHIDWTAGAVRLLTEQSAWPDTDRPRR 442 Query: 414 GAVSSFGAGGANAHAIISMPAAGV 437 AVSSFG G NAH II P+ V Sbjct: 443 AAVSSFGVSGTNAHVIIEQPSEPV 466 Score = 290 bits (741), Expect = 3e-76 Identities = 161/433 (37%), Positives = 217/433 (50%), Gaps = 10/433 (2%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 +++P+ I GM PGG+ SP LW + +++S FP DRGW V+ L Sbjct: 1829 SSEPVAIVGMGCRFPGGVVSPEGLWEVVLSGADVISEFPTDRGWDVEGLYDPDPDRPGKT 1888 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 GGF+D FD GFFGIS REA+ + PQQR+ + +W+A E +GI+P + G+ G Sbjct: 1889 YGRRGGFVDAVADFDAGFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTG 1948 Query: 129 CFVGMSPMEYGPRASVADAYSGHRIASLGQLGG----AARISHSLGLIGPSISVDTXXXX 184 F G+ +Y R GH +G A R+S++ GL GPS+SVDT Sbjct: 1949 VFAGVMYHDYASRLREVP---GHLEGLMGTGNATSVIAGRLSYTFGLEGPSVSVDTACSS 2005 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R ECE ALAG V VM +P AF F+R L+ DG C+A+ A GT Sbjct: 2006 SLVALHLAVQALRAGECEMALAGGVTVMATPEAFINFSRQRGLATDGRCKAFGAGADGTG 2065 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 W EGAGM+LV N +G + P +Q++VIR+ L A Sbjct: 2066 WAEGAGMLLVERLSDAQRLGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALATA 2125 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXX 361 G+ P ++ +EGHGT T GDP+E+ AL TYG A LGS+KSN GH+Q Sbjct: 2126 GLGPTDIDAVEGHGTGTSLGDPIEVQALQATYGQERPAERPLWLGSLKSNIGHAQAAAGV 2185 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 + G +P TL AD P+ +DW +RL T+ W R AVSSFG Sbjct: 2186 GGVIKMVMALREGVLPRTLHADEPSPHIDWTAGAVRLLTEQSAWPDTDRPRRAAVSSFGF 2245 Query: 422 GGANAHAIISMPA 434 G NAH II P+ Sbjct: 2246 SGTNAHVIIEQPS 2258 >tr|Q0QMQ1|Q0QMQ1_9ACTO Tax_Id=270689 SubName: Full=Polyketide synthase type I;[Streptomyces aculeolatus] Length = 4308 Score = 301 bits (772), Expect = 8e-80 Identities = 163/429 (37%), Positives = 218/429 (50%), Gaps = 4/429 (0%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 +AG DP+VI GMA PGG+ SPA LW L E R+ + FP DRGW ++ L Sbjct: 1050 AAGDDDPVVIVGMACRYPGGVGSPAELWRLLREERDAIGDFPADRGWDLEGLHDPDPDRA 1109 Query: 66 WGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGT 125 GGFLD FD FFGIS REA+ + PQQR+ + +W+A E +GI G G+ Sbjct: 1110 GTSYTARGGFLDDVAGFDAEFFGISPREALAMDPQQRLLLETSWEAFERAGIAAGPLRGS 1169 Query: 126 EGGCFVGMSPMEYGPRA-SVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 G FVG + +YGPR AD G+ + + RI++ GL GP+++VDT Sbjct: 1170 RTGVFVGATAQDYGPRMHEAADGLEGYVLTGTTPSVASGRIAYVFGLEGPAVTVDTACSS 1229 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R EC+ ALAG V V+ +PG F EF+R L+ DG C+ ++ A GT Sbjct: 1230 SLVALHLAAQSIRAGECDTALAGGVTVLSTPGMFVEFSRQRGLAADGRCKPFAAGADGTG 1289 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 W EG G++++ N +G + P AQE+VIR L+ A Sbjct: 1290 WAEGVGVLVLERLSTARRNGHRPLAVVRGTAINQDGASNGLTAPNGLAQERVIRAALDNA 1349 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE---ALLGSIKSNAGHSQXXXXX 361 G+ P +V +E HGT T GDP+E AL TYG +E LGS+KSN GH+Q Sbjct: 1350 GLGPGDVDAVEAHGTGTELGDPIEAEALLATYGQGRAEDRPVWLGSLKSNIGHTQAAAGV 1409 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +HG++P TL D PT V+W G+ L T W R AVSSFG Sbjct: 1410 AGIIKMVQALRHGELPATLHVDEPTPHVEWAAGGVSLLTGARPWPEAGRARRAAVSSFGV 1469 Query: 422 GGANAHAII 430 G NAH I+ Sbjct: 1470 SGTNAHVIL 1478 Score = 293 bits (750), Expect = 3e-77 Identities = 163/436 (37%), Positives = 218/436 (50%), Gaps = 5/436 (1%) Query: 5 GSAGAAD-PIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDL 63 G+A AAD P+VI GMA PGG+ SP LW + E RE L PFP DRGW +D L Sbjct: 2772 GAAEAADDPVVIVGMACRYPGGVASPEDLWRLVTEGREGLGPFPTDRGWDLDALFHPDQD 2831 Query: 64 EGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTA 123 +G FL A FDP FG+S REA+ + PQQR+ + +W+A E +G++P + Sbjct: 2832 RPGTSHTRAGHFLYRAGDFDPDLFGLSRREALAMDPQQRLLLETSWEAFERAGVDPAALR 2891 Query: 124 GTEGGCFVGMSPMEYGPRASV-ADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXX 182 G+ G F G+ +Y A+ GH + + R+S++ GL GP+++VDT Sbjct: 2892 GSRTGVFTGLMYHDYAVGVDAGAEGVEGHVLTGTQASVASGRVSYAFGLEGPAVTVDTAC 2951 Query: 183 XXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATG 242 +R EC+ ALAG V VM PG F EF+R LS DG C++++ A G Sbjct: 2952 SSSLVALHLAAQSLRTGECDMALAGGVTVMAGPGTFVEFSRQRGLSADGRCKSFAAGADG 3011 Query: 243 TVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLE 302 T W EG G+++V N +G + P +Q++VIR L+ Sbjct: 3012 TGWAEGVGVLVVERLSAARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALD 3071 Query: 303 VAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE---ALLGSIKSNAGHSQXXX 359 AG+ +V +E HGT T GDP+E AL TYG E LGSIKSN GH+Q Sbjct: 3072 NAGLGLADVDAVEAHGTGTTLGDPIEAEALLATYGRGRDEDRPLWLGSIKSNIGHAQAAA 3131 Query: 360 XXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSF 419 +HG++P TL D PT VDW G+ L T W R AVSSF Sbjct: 3132 GVAGIIKMVHAMRHGELPATLHVDEPTPHVDWAAGGVSLLTDARPWPEVDRPRRAAVSSF 3191 Query: 420 GAGGANAHAIISMPAA 435 G G NAH I+ A Sbjct: 3192 GVSGTNAHVILEQAEA 3207 Score = 215 bits (548), Expect = 8e-54 Identities = 154/460 (33%), Positives = 207/460 (45%), Gaps = 41/460 (8%) Query: 4 NGSAG--AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVS 61 +G AG A I + GMA PG D P + W L + + + P P RG P Sbjct: 5 SGRAGVPADRRIAVVGMACRVPGAAD-PGAFWRLLRDGVDAVGPAPAGRGLP-------- 55 Query: 62 DLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGS 121 +G GGFLD FD FFG+S REA + PQQR+A+ +AW+ALE++G+ PG Sbjct: 56 --DG-----AHGGFLDDVDRFDAAFFGMSPREAAAVDPQQRLALELAWEALEHAGLRPGL 108 Query: 122 TAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTX 181 G+ G FVG +Y A S H L + A R+SH LGL GPS++VDT Sbjct: 109 LRGSRTGVFVGAMTDDYARLQHAAGVVSAHSTTGLSRAALANRLSHVLGLTGPSLAVDTA 168 Query: 182 XXXXXXXXXXXXXXVREDECEWALAGAV--CVMGSPGAFYE-FARLNALSEDGHCRAYSD 238 + + E A+ G V ++ A E F L + D CR + Sbjct: 169 QSSGLAAVHLAVRSLLDGESTLAVTGGVQLNILAEGFAAAELFGALAPGAADARCRVFDA 228 Query: 239 NATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIR 298 A G V GEG G+V++ +G G+ + P AQE VIR Sbjct: 229 RADGYVRGEGGGIVVLKPLAAALADGDPVHGVILGSALG-SGTGRTLTAPDPAAQESVIR 287 Query: 299 KTLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYG----AAGSEALLGSIKSNAGH 354 AG+DP E +E HGT TP GDPVE AL G AG E ++GS+K+N GH Sbjct: 288 AAYRDAGVDPDEARYVELHGTGTPMGDPVEAAALAAALGTARRGAGEELVVGSVKTNIGH 347 Query: 355 SQXXXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEW--------- 405 + +HG++PP+L + P + D LR+ T W Sbjct: 348 LEGAAGAVGLIKALLSLKHGELPPSLHFEEPHPRIPLDELKLRVRTGAGPWPREREQPAA 407 Query: 406 -EPKHGVRYGA-VSSFGAGGANAHAIIS----MPAAGVGQ 439 E + R A VSSFG GG N H ++S PA G G+ Sbjct: 408 KEGESAERLVAGVSSFGMGGTNCHVVLSDWRPAPADGHGE 447 >tr|B3TMQ8|B3TMQ8_9ACTO Tax_Id=46161 SubName: Full=Polyketide synthase;[Actinomadura kijaniata] Length = 6241 Score = 301 bits (772), Expect = 8e-80 Identities = 167/429 (38%), Positives = 221/429 (51%), Gaps = 5/429 (1%) Query: 6 SAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEG 65 + GA DPI I GMA PGG+ +P LW + + +S FP +RGW ++ L Sbjct: 1017 TGGADDPIAIVGMACRFPGGVRTPEQLWRLVETGTDAISDFPDNRGWDLNALFDPDAEAS 1076 Query: 66 WGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGT 125 GGFL A FDP FFGIS REA+ + PQQR+ + V+W+ALE +G++P S G Sbjct: 1077 GTSAVRRGGFLPDADLFDPAFFGISPREALAMDPQQRLLLEVSWEALERAGVDPLSLRGG 1136 Query: 126 EGGCFVGMSPMEYGPRAS-VADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXX 184 G FVG EYGPR S AD G R+ + RI+++LGL GP+ +VDT Sbjct: 1137 RAGVFVGAMAQEYGPRLSDAADGLEGFRLTGTSVSVASGRIAYTLGLQGPAFTVDTACSS 1196 Query: 185 XXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTV 244 +R+ EC A+AG V VM SPG F EF+R LS DG C+A++D A GT Sbjct: 1197 SLVALHLAVRALRDGECPLAVAGGVNVMASPGIFVEFSRQQGLSPDGTCKAFADAADGTG 1256 Query: 245 WGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVA 304 W EG GMV++ N +G + P +Q +VIR+ L Sbjct: 1257 WSEGVGMVVLERLSDARRNGHRVLALIRGSAINSDGASNGLTAPNGPSQVRVIRQALADG 1316 Query: 305 GIDPVEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXX 361 G+ P +V +E HGT T GDP+E AL + YG A + LGS+KSN GH+Q Sbjct: 1317 GLSPADVDAVEAHGTGTRLGDPIEAQALIEAYGRDRPADAPLWLGSLKSNIGHAQAAAGI 1376 Query: 362 XXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGA 421 +H +P TL D PT+ VDW +RL + W P VR AVSSFG Sbjct: 1377 GGLIKMVMALRHRSLPRTLHVDAPTRRVDWSAGAVRLLAEARPW-PGTPVRRAAVSSFGI 1435 Query: 422 GGANAHAII 430 G NAH ++ Sbjct: 1436 SGTNAHLVL 1444 Score = 294 bits (752), Expect = 2e-77 Identities = 163/428 (38%), Positives = 212/428 (49%), Gaps = 3/428 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I GMA PGG SP +LW +A+ + + FP DRGW ++ L Sbjct: 2764 EPIAIVGMACRYPGGATSPEALWRLVAQGVDAIGEFPTDRGWDLEGLYDPDPDHPGTSYT 2823 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FDP FFGIS REA+ PQQR+ + AW+ LEN+GINP + G+ G F Sbjct: 2824 RHGGFLYDAADFDPEFFGISPREALATDPQQRLLLETAWETLENAGINPHTLRGSHTGVF 2883 Query: 131 VGMSPMEYGPRA--SVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 G+ +YG R D + G IA + R+S+ L L GP+++VDT Sbjct: 2884 TGVMYDDYGNRLMQDSPDGFEGFLIAGTQTSVASGRVSYVLDLAGPALTVDTACSSSLVA 2943 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R EC+ ALAG +M +PG F EF+R L+ DG +++S A G W EG Sbjct: 2944 LHLAIQALRNGECDLALAGGATIMATPGPFIEFSRQRGLAPDGRSKSFSAAADGAAWSEG 3003 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 G++LV N +G + P AQ +VIR+ L AG+ P Sbjct: 3004 VGLLLVERLSDAQRNGHRVLAVVRGSAVNQDGASNGLTAPSAAAQRRVIRQALTNAGLSP 3063 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXXXXX 367 +V +E HGT T GDP+E A+ TYG L LGSIKSN GH+Q Sbjct: 3064 ADVDAVEAHGTGTTLGDPIEAEAILATYGQNRDRPLWLGSIKSNIGHTQAAAGVAGIIKM 3123 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 +HG +P TL D PT VDWD + L T H+W R VSSFG G NAH Sbjct: 3124 VQAMRHGVLPRTLHVDEPTPHVDWDTGHVELLTHNHDWPTGDRPRRAGVSSFGISGTNAH 3183 Query: 428 AIISMPAA 435 II P A Sbjct: 3184 VIIEEPPA 3191 Score = 291 bits (746), Expect = 9e-77 Identities = 167/433 (38%), Positives = 217/433 (50%), Gaps = 7/433 (1%) Query: 3 TNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSD 62 T + A +PI I GMA PGG SP +LW +++ + + FP DRGW ++ L Sbjct: 4473 TASTIPADEPIAIVGMACRYPGGATSPEALWRLVSQGVDAIGEFPTDRGWDLESLYDPDP 4532 Query: 63 LEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGST 122 GGFL A FDP FFGIS REA+ PQQR+ + +W+ EN+GINP + Sbjct: 4533 DHPGTSYTRHGGFLYNAADFDPEFFGISPREALATDPQQRLLLETSWETFENAGINPHTL 4592 Query: 123 AGTEGGCFVGMSPMEYGPRA--SVADAYSGHRIASLGQLGGAA--RISHSLGLIGPSISV 178 G+ G F G+ +YG R + Y G G G A RI+++ GL GP+ISV Sbjct: 4593 RGSHTGVFTGVMYDDYGNRLMQQAPEGYEGQ--LGTGSAGSVASGRIAYTFGLEGPAISV 4650 Query: 179 DTXXXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSD 238 DT +R EC+ ALAG V VM +PG F EF+R L+ DG + ++ Sbjct: 4651 DTACSSSLVALHLAIQALRNGECDLALAGGVTVMATPGTFVEFSRQRGLAPDGRPKPFAA 4710 Query: 239 NATGTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIR 298 A GT WGEG G++LV N +G + P +Q++VIR Sbjct: 4711 AADGTSWGEGVGLLLVERLSDAQRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIR 4770 Query: 299 KTLEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQX 357 + L AG+ P EV +E HGT T GDP+E AL TYG L LGSIKSN GH+Q Sbjct: 4771 QALANAGLAPAEVDAVEAHGTGTRLGDPIEANALLTTYGQDRDRPLWLGSIKSNIGHTQA 4830 Query: 358 XXXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVS 417 +HG +P TL D PT VDWD + L T H+W R AVS Sbjct: 4831 AAGVAGIIKMVQAMRHGVLPRTLHVDEPTPHVDWDAGRVELLTDNHDWPELDRPRRAAVS 4890 Query: 418 SFGAGGANAHAII 430 SFG G NAH I+ Sbjct: 4891 SFGISGTNAHVIL 4903 Score = 193 bits (491), Expect = 3e-47 Identities = 134/429 (31%), Positives = 188/429 (43%), Gaps = 15/429 (3%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +PI I G++ P D PA+ W L + R ++ P R W + EG + Sbjct: 16 EPIAIVGLSCRLPQAPD-PAAFWRLLLDGRSAVTETPPGR-W--------TGAEGTAGL- 64 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFLD FD FF +S REA + PQQR+ + +AW+A+E++ I P + AG G F Sbjct: 65 RHGGFLDDVDRFDAAFFDVSPREAASMDPQQRLMLELAWEAVEDAMIAPATLAGGRTGVF 124 Query: 131 VGMSPMEYGPRASVADAYSGHRIASLGQLGG--AARISHSLGLIGPSISVDTXXXXXXXX 188 VG +Y G R + G L G A R+S++LGL GPS++VD Sbjct: 125 VGAIGDDYAALMRRHGPEGGTRHSLAGTLRGIIANRVSYTLGLRGPSLTVDAAQASALVA 184 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 + E ALAG V + G E R LS DG C + A G V GEG Sbjct: 185 VHLACESIASGESAMALAGGVNLNLDTGTALETERFGGLSPDGRCHTFDARANGYVRGEG 244 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 VL+ N++G + VP AQ +VIR AG++P Sbjct: 245 GAFVLLKPLSRALADGDRVYCVIRGSGVNNDGATDGLTVPDADAQREVIRLAWRRAGLEP 304 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGAAGSE--ALLGSIKSNAGHSQXXXXXXXXXX 366 V +E HGT T GDPVE ++ GAA ++ +GS K+N GH + Sbjct: 305 GAVQYVELHGTGTRVGDPVEAASVGAALGAARADGPVHVGSTKTNVGHLEGAAGIVGLVK 364 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +H IP +L + P +D + + T W V+SFG GG N Sbjct: 365 AALCVRHRMIPASLNFETPNPEIDLAALNIEVRTAPGPWPRPDAPLVAGVNSFGMGGTNC 424 Query: 427 HAIISMPAA 435 H +++ P A Sbjct: 425 HVVVAEPPA 433 >tr|C3VLV4|C3VLV4_9ACTO Tax_Id=639005 (becA)SubName: Full=Polyketide synthase type I;[Streptomyces sp. DSM 21069] Length = 5582 Score = 301 bits (771), Expect = 1e-79 Identities = 168/429 (39%), Positives = 217/429 (50%), Gaps = 2/429 (0%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 A DPIVI GMA PGG +P LW + + +S FP DRGW +D L Sbjct: 1025 ADDPIVIVGMACRYPGGASTPDELWQLVDDGVSAISGFPTDRGWDLDALYDPEPGVRGKT 1084 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 GGFLD A FD FFGIS REA + PQQR+ ++V W+ALE +GI+P G+ G Sbjct: 1085 YTRHGGFLDEAAEFDTEFFGISPREATAMDPQQRLLLQVTWEALERAGIDPDGLQGSSTG 1144 Query: 129 CFVGMSPMEYGPRASVAD-AYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 FVG EYGPR D G+ + + RIS++ GL GP+++VDT Sbjct: 1145 VFVGAMSQEYGPRLHEGDDGLGGYLLTGTTASVVSGRISYTFGLEGPAVTVDTACSSSLV 1204 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R EC ALAG V VM +PG F EF + L+ DG C++++ A GT+W E Sbjct: 1205 AMHQAAQALRVGECSLALAGGVAVMATPGMFVEFGQQRGLAPDGRCKSFAGAADGTIWAE 1264 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 GAGMVL+ N +G + P +Q++VI L AG+ Sbjct: 1265 GAGMVLLERLSDAKANGHTVLAVIRGSAVNQDGASNGLTAPNGPSQQRVITAALAGAGLT 1324 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXXXX 366 P +V +E HGT TP GDP+E AL TYG E L LGS+KSN GH+Q Sbjct: 1325 PDQVDAVEAHGTGTPLGDPIEAQALLATYGQNREEPLWLGSLKSNIGHTQAAAGIGGVIK 1384 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +HG +P TL D P+ +DWD +RL T+ W R AVSSFG G NA Sbjct: 1385 MIQAMRHGTLPRTLHVDEPSPHIDWDSGNVRLLTEARAWPETDHPRRSAVSSFGISGTNA 1444 Query: 427 HAIISMPAA 435 H I+ A Sbjct: 1445 HLILEQAPA 1453 Score = 291 bits (746), Expect = 9e-77 Identities = 160/424 (37%), Positives = 215/424 (50%), Gaps = 2/424 (0%) Query: 9 AADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQ 68 AADPIVI GM PGG D+P +LW +A+ R+ + FP +RGW +++L Sbjct: 4570 AADPIVIVGMGCRFPGGADTPEALWKLVADERDAVGAFPDNRGWDIENLFDDDPDVRGKS 4629 Query: 69 VCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGG 128 GGFL A FDP FFGIS REA+ L PQQR+ + W+A EN+GI P + G G Sbjct: 4630 YASEGGFLYDADRFDPEFFGISPREALALDPQQRLLLETTWEAFENAGIRPDTLRGKPVG 4689 Query: 129 CFVGMSPMEYGPRASVA-DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 F G++ EY + G+ + + RIS++LGL GP+++VDT Sbjct: 4690 VFAGVAAGEYVSLTHHGGEPVEGYLLTGTTASVASGRISYTLGLEGPAVTVDTACSSSLV 4749 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R +E ALAG +M + G F EF+R L+ D ++Y+ A GT+W E Sbjct: 4750 AMHLACQSLRNNESTMALAGGATIMSNAGMFMEFSRQRGLAPDSRAKSYAGAADGTIWAE 4809 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 GAGMVL+ N +G + P +Q++VI L AG+ Sbjct: 4810 GAGMVLLERLSDAKANGHTVLAVIRGSAVNQDGASNGLTAPNGPSQQRVINTALASAGLT 4869 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXXXX 366 P +V +EGHGT TP GDP+E AL TYG E L LGS KSN GH+Q Sbjct: 4870 PDQVDAVEGHGTGTPLGDPIEAQALLSTYGQNREEPLWLGSFKSNIGHAQAAAGVGGVIK 4929 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +HG +P TL D P+ +DWD +RL T+ W R AVSSFG G NA Sbjct: 4930 MIQAMRHGTLPRTLHVDEPSPNIDWDSGNVRLLTEARAWPETDRPRRSAVSSFGISGTNA 4989 Query: 427 HAII 430 H I+ Sbjct: 4990 HLIL 4993 Score = 273 bits (697), Expect = 4e-71 Identities = 153/430 (35%), Positives = 210/430 (48%), Gaps = 6/430 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVS-DLEGWGQV 69 +PI + GM PGG +P LW + E + + FP +RGW +++L D+ G Sbjct: 2795 EPIAVIGMGCRYPGGATTPDELWRLVTEGVDAIGSFPTNRGWDLEELFDPDPDMRG-KTY 2853 Query: 70 CDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGC 129 GGFL A FDP FFGIS REA+ L PQQR+ + W+ EN+GI P + G G Sbjct: 2854 ARKGGFLYDADRFDPEFFGISPREALALDPQQRLLLETTWETFENAGIRPDTLRGKPVGV 2913 Query: 130 FVGMSPMEYGPRASVA-DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 F G+ EYG + G + + R++++LGL GP+++VDT Sbjct: 2914 FAGVVTQEYGSLVHRGTEPVDGFLLTGTTASVASGRLAYTLGLEGPAVTVDTACSSSLVA 2973 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R +E ALAG VM +PG F EF+R L+ DG C++++ A GT+W EG Sbjct: 2974 MHLACQSLRNNESTMALAGGATVMANPGMFLEFSRQRGLAPDGRCKSFAGGADGTIWAEG 3033 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 AGMVL+ N +G + P +Q++VI L AG+ Sbjct: 3034 AGMVLLERLSDAKANGHTVLAVIRGSAVNQDGASNGLTAPSGPSQQRVITAALAGAGLTS 3093 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYG---AAGSEALLGSIKSNAGHSQXXXXXXXXX 365 +V +EGHGT TP GDP+E AL TYG A LGS KSN GH+Q Sbjct: 3094 DQVDAVEGHGTGTPLGDPIEAQALLATYGQGREADQPLWLGSFKSNIGHAQAAAGIGGVI 3153 Query: 366 XXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGAN 425 +HG +P TL D P+ ++W +RL T+ W R AVSSFG G N Sbjct: 3154 KMIQAMRHGTLPRTLHVDEPSPHINWASGNVRLLTEERAWPETDHPRRSAVSSFGISGTN 3213 Query: 426 AHAIISMPAA 435 AH I+ A Sbjct: 3214 AHVILEQAPA 3223 Score = 224 bits (572), Expect = 1e-56 Identities = 145/424 (34%), Positives = 203/424 (47%), Gaps = 8/424 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 D I I+GM+ P D+ S W L R ++ P DR W D++L S E Sbjct: 17 DAIAITGMSCRLPQAPDAN-SFWELLRSGRSAITEVPPDR-WDPDEVLPDSP-ERHRAAL 73 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFLD FD FFGIS REA+ + PQQR+ +AW+ALE++GI P + T Sbjct: 74 RHGGFLDRVDQFDAAFFGISPREAVAIDPQQRLFAELAWEALEDAGIVPETLRSTATAVI 133 Query: 131 VGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXXXX 190 VG +Y A A + H + L + A R+S++LGL GPS++VD+ Sbjct: 134 VGAIAGDYAALAHRGGAITQHSLPGLNRGVIANRVSYALGLNGPSMAVDSAQSSSLVAVH 193 Query: 191 XXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEGAG 250 +R+ EC ALAG V + +P + LS DG C + A G V GEG G Sbjct: 194 LAVESLRKGECTLALAGGVALNFAPESAEVAGMFGGLSPDGRCFTFDARANGYVRGEGGG 253 Query: 251 MVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDPVE 310 +V++ N++G + VP AQ V+R+ E AG+DP E Sbjct: 254 VVVLKPLAHAVRDGDTVYGVIRGTAVNNDGSTDGLTVPSAEAQATVLRQACEDAGVDPAE 313 Query: 311 VGMIEGHGTATPAGDPVELIALFKTYGA---AGSEALLGSIKSNAGHSQXXXXXXXXXXX 367 V +E HGT TP GDP+E + YG+ AGS L+GS K+N GH + Sbjct: 314 VRYVELHGTGTPTGDPLEAAGVGAAYGSARPAGSPVLVGSAKTNVGHLEGAAGIVGLIKT 373 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 +H +IP +L + P +D + LR+ T W P + G VSSFG GG N H Sbjct: 374 ALSIRHREIPASLNYETPNPRIDPEALNLRVQTASGPW-PDAPLLAG-VSSFGVGGTNCH 431 Query: 428 AIIS 431 +++ Sbjct: 432 VVLA 435 >tr|B5L6K8|B5L6K8_MICCH Tax_Id=1874 SubName: Full=Putative type I polyketide synthase;[Micromonospora chalcea] Length = 6305 Score = 301 bits (770), Expect = 1e-79 Identities = 171/432 (39%), Positives = 223/432 (51%), Gaps = 6/432 (1%) Query: 3 TNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSD 62 T DPI I GMA PGG+ SP LW + + +S FP +RGW +D L Sbjct: 1014 TRADDATDDPIAIVGMACRFPGGVRSPEHLWRLVETGTDAISDFPDNRGWDLDTLFDPEA 1073 Query: 63 LEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGST 122 G V GGFL A FDP FFGIS REA + PQQRV + V+W+ALE +G++P S Sbjct: 1074 ASGTSSV-RRGGFLLDADLFDPAFFGISPREAQAMDPQQRVLLEVSWEALERAGLDPLSL 1132 Query: 123 AGTEGGCFVGMSPMEYGPR-ASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTX 181 + G FVG EYGPR A A G + + RI+++LGL GP+++VDT Sbjct: 1133 RNSRTGVFVGAMSQEYGPRLAEGARELEGFLLTGTTASVASGRIAYTLGLQGPTLTVDTA 1192 Query: 182 XXXXXXXXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNAT 241 +R EC A+AG V VM +PG F EF+R LS G CRA++D A Sbjct: 1193 CSSSLVALHLAARALRAGECGLAIAGGVTVMSAPGIFVEFSRQQGLSPTGRCRAFADAAD 1252 Query: 242 GTVWGEGAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTL 301 GT W EGAGMV++ N +G + P +Q+QVIR+ L Sbjct: 1253 GTAWSEGAGMVVLERLSDARRNGHRVLALVRGSAVNSDGTSNGLTAPNGASQQQVIRQAL 1312 Query: 302 EVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAA---GSEALLGSIKSNAGHSQXX 358 AG+ PV+V ++E HGT T GDP+E A+ TYG + LGS+KSN GH+Q Sbjct: 1313 ADAGLRPVDVDVVEAHGTGTRLGDPIEAQAILDTYGHGRPDDAPLWLGSLKSNIGHAQAA 1372 Query: 359 XXXXXXXXXXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSS 418 +H +P TL D PT+ VDW +RL T+ W P+ VR AVSS Sbjct: 1373 AGVGGLIKMVLALRHESLPRTLHVDRPTRQVDWSAGTVRLLTEERPW-PRATVRRAAVSS 1431 Query: 419 FGAGGANAHAII 430 FG G NAH ++ Sbjct: 1432 FGISGTNAHLVL 1443 Score = 286 bits (732), Expect = 4e-75 Identities = 159/429 (37%), Positives = 214/429 (49%), Gaps = 4/429 (0%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 +P+ I GM PGGI SP LW + + +S FP DRGW +D L Sbjct: 2780 EPVAIVGMGCRYPGGIRSPHDLWQLVLNGTDAISEFPTDRGWNLDTLYHPDPDHPGTSYT 2839 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFL A FDP FFG+S REA+ PQQR+ + W+ LE++GI+P + GT G F Sbjct: 2840 RHGGFLHDAADFDPDFFGMSPREALATDPQQRLLLETTWETLEHAGIDPTTLRGTHTGVF 2899 Query: 131 VGMSPMEYGPRASVA--DAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 G+ +YG R A D Y G ++ + R++++L L GP+++VDT Sbjct: 2900 TGVMYDDYGNRLMQASPDGYEGFLLSGNQTSVASGRVAYALDLAGPALTVDTACSSSLVA 2959 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R EC+ ALAG V VM +P +F EF+R L+ DG ++++ +A G W EG Sbjct: 2960 LHLAVQALRNGECDLALAGGVTVMATPASFVEFSRQRGLASDGRSKSFAASADGVAWSEG 3019 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 G++LV N +G + P AQ ++IR+ L AG+ P Sbjct: 3020 VGLLLVERLSDAQRNGHRILAVVRATAVNSDGASNGLTAPSAPAQRRLIRQALATAGLTP 3079 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXXXXX 367 +V +E HGT T GDP+E AL TYG + L LGSIKSN GH+Q Sbjct: 3080 ADVDAVEAHGTGTKLGDPIEAEALLATYGQDRDQPLWLGSIKSNIGHTQAAAGAAGIIKM 3139 Query: 368 XXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANAH 427 QHG +P TL D PT VDW + L T W + R AVSSFG G NAH Sbjct: 3140 IQAIQHGVLPKTLHVDTPTPHVDWTTGNVALLTDTQPWPDQGRPRRAAVSSFGISGTNAH 3199 Query: 428 AIISM-PAA 435 I+ PAA Sbjct: 3200 IILEQAPAA 3208 Score = 281 bits (719), Expect = 1e-73 Identities = 158/424 (37%), Positives = 214/424 (50%), Gaps = 5/424 (1%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVS-DLEGWGQV 69 DPIVI GMA PG + SP LW E + +SPFP DRGW ++ L D G V Sbjct: 4521 DPIVIVGMACRYPGDVRSPEDLWRMTVEGVDAVSPFPEDRGWDIERLFDPDPDAPGKSYV 4580 Query: 70 CDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGC 129 + GGFL A FD FFGIS REA+ + PQQR+ + +W+ EN+GI+P S G+ G Sbjct: 4581 RE-GGFLTDAAEFDAAFFGISPREALAMDPQQRLLLETSWETFENAGIDPESLRGSRTGV 4639 Query: 130 FVGMSPMEYGPRA--SVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXX 187 F G+ +YG R + G + + R+S++ GL GP++++DT Sbjct: 4640 FTGVMYDDYGSRFLHHQPAGFDGQLVTGSAGSVASGRVSYTYGLEGPAVTIDTACSSSLV 4699 Query: 188 XXXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGE 247 +R EC+ ALAG V VM +P +F EF+R L+ D ++++ A GT W E Sbjct: 4700 ALHLAAQALRNGECDLALAGGVTVMATPASFVEFSRQRGLAPDARVKSFAAAADGTSWSE 4759 Query: 248 GAGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGID 307 G G++LV N +G + P +QE++IR+ L A + Sbjct: 4760 GVGLLLVERLSDAQRHGHRILAVVRATAVNQDGASNGLTAPNGPSQERLIRRALAEARLT 4819 Query: 308 PVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEAL-LGSIKSNAGHSQXXXXXXXXXX 366 P +V +E HGT T GDP+E AL TYG ++ L LGSIKSN GH+Q Sbjct: 4820 PADVDAVEAHGTGTKLGDPIEAQALLATYGQNRNQPLWLGSIKSNIGHTQAAAGAAGIIK 4879 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 QHG +P TL D PT VDW + L T W + R AVSSFG G NA Sbjct: 4880 MIQAIQHGVLPKTLHVDAPTPHVDWTTGNVALLTDTQPWPDQGRPRRAAVSSFGISGTNA 4939 Query: 427 HAII 430 H I+ Sbjct: 4940 HIIL 4943 Score = 212 bits (539), Expect = 9e-53 Identities = 144/427 (33%), Positives = 193/427 (45%), Gaps = 14/427 (3%) Query: 11 DPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSVSDLEGWGQVC 70 D I + G++ P D PA+ W LAE R ++ P DR WP D Sbjct: 17 DAIAVVGLSCRLPQAPD-PAAFWRLLAEGRSAVTATPPDR-WP--------DAGADNPGL 66 Query: 71 DSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPGSTAGTEGGCF 130 GGFLD FDP FFGIS REA + PQQR+ + +AW+ALE++ I P S AG G F Sbjct: 67 RHGGFLDDVDRFDPAFFGISPREAAGMDPQQRLMLELAWEALEDAMIVPASLAGGPVGVF 126 Query: 131 VGMSPMEYGP--RASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDTXXXXXXXX 188 VG +Y + S DA H + + A RIS++LGL GPS++VD Sbjct: 127 VGAIGDDYAALLQRSGPDAVDQHSLTGTRRGIIANRISYTLGLRGPSLTVDAAQASALVA 186 Query: 189 XXXXXXXVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNATGTVWGEG 248 +R E ALAG V + + + E R ALS DG C + A G V GEG Sbjct: 187 VHLAAESIRSGESTLALAGGVNLNVATASAVETERFGALSPDGRCYTFDSRANGYVRGEG 246 Query: 249 AGMVLVXXXXXXXXXXXXXXXXXXXXXTNHNGKGKPILVPRVRAQEQVIRKTLEVAGIDP 308 G V++ N++G + VP V AQ +V+ + E G+ P Sbjct: 247 GGFVVLKRLATALADGDEIYCLVRGTAVNNDGATAGLTVPSVDAQREVMLRAHERTGLTP 306 Query: 309 VEVGMIEGHGTATPAGDPVELIALFKTYGA--AGSEALLGSIKSNAGHSQXXXXXXXXXX 366 V +E HGT T GDPVE ++ G AGS L+GS K+N GH + Sbjct: 307 GAVQYVELHGTGTRVGDPVEAASVGAALGTARAGSPLLVGSAKTNVGHLEGAAGIVGLLK 366 Query: 367 XXXXXQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFGAGGANA 426 +H +P +L P +D L + T L W V+SFG GG N Sbjct: 367 AALSVKHRLLPASLNFAEPNPDIDTAALNLEVNTTLRPWPRADEPLVAGVNSFGMGGTNC 426 Query: 427 HAIISMP 433 H ++S P Sbjct: 427 HVVVSEP 433 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.316 0.134 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 3,184,834,837 Number of extensions: 125242558 Number of successful extensions: 308222 Number of sequences better than 10.0: 10504 Number of HSP's gapped: 280257 Number of HSP's successfully gapped: 12033 Length of query: 439 Length of database: 3,846,993,858 Length adjustment: 141 Effective length of query: 298 Effective length of database: 2,257,190,235 Effective search space: 672642690030 Effective search space used: 672642690030 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 82 (36.2 bits)