BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_3695 (1024 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HM91|B2HM91_MYCMM Tax_Id=216594 (mbtD)SubName: Full=Polyket... 1758 0.0 tr|A0PTV2|A0PTV2_MYCUA Tax_Id=362242 (mbtD)SubName: Full=Polyket... 1737 0.0 tr|B1MPE9|B1MPE9_MYCA9 Tax_Id=561007 SubName: Full=Putative poly... 913 0.0 tr|Q5Z1T1|Q5Z1T1_NOCFA Tax_Id=37329 (nbtC)SubName: Full=Putative... 749 0.0 tr|D0L269|D0L269_GORB4 Tax_Id=526226 SubName: Full=Acyl transfer... 740 0.0 tr|C2AVC9|C2AVC9_TSUPA Tax_Id=521096 SubName: Full=Putative poly... 494 e-137 tr|A1TBS7|A1TBS7_MYCVP Tax_Id=350058 SubName: Full=Acyl transfer... 409 e-112 tr|Q73XY4|Q73XY4_MYCPA Tax_Id=1770 (mbtD)SubName: Full=MbtD;[Myc... 401 e-109 tr|Q7TYQ6|Q7TYQ6_MYCBO Tax_Id=1765 (mbtD)SubName: Full=POLYKETID... 397 e-108 tr|P71719|P71719_MYCTU Tax_Id=1773 (mbtD)SubName: Full=POLYKETID... 397 e-108 tr|C6DNA3|C6DNA3_MYCTK Tax_Id=478434 SubName: Full=Polyketide sy... 397 e-108 tr|C1AQU4|C1AQU4_MYCBT Tax_Id=561275 (mbtD)SubName: Full=Polyket... 397 e-108 tr|A5U574|A5U574_MYCTA Tax_Id=419947 (mbtD)SubName: Full=Putativ... 397 e-108 tr|A1KL71|A1KL71_MYCBP Tax_Id=410289 (mbtD)SubName: Full=Polyket... 397 e-108 tr|Q7D790|Q7D790_MYCTU Tax_Id=1773 SubName: Full=Polyketide synt... 397 e-108 tr|A5WPZ6|A5WPZ6_MYCTF Tax_Id=336982 SubName: Full=Polyketide sy... 397 e-108 tr|A4KJD1|A4KJD1_MYCTU Tax_Id=395095 SubName: Full=Polyketide sy... 397 e-108 tr|A2VKA7|A2VKA7_MYCTU Tax_Id=348776 SubName: Full=Polyketide sy... 397 e-108 tr|A4T2C9|A4T2C9_MYCGI Tax_Id=350054 SubName: Full=Acyl transfer... 396 e-108 tr|A0QE93|A0QE93_MYCA1 Tax_Id=243243 SubName: Full=MbtD protein;... 396 e-108 tr|A0R0U6|A0R0U6_MYCS2 Tax_Id=246196 SubName: Full=Polyketide sy... 378 e-102 tr|D0L275|D0L275_GORB4 Tax_Id=526226 SubName: Full=Acyl transfer... 257 5e-66 tr|A3Q279|A3Q279_MYCSJ Tax_Id=164757 SubName: Full=Acyl transfer... 241 3e-61 tr|Q1B6B0|Q1B6B0_MYCSS Tax_Id=164756 SubName: Full=Acyl transfer... 240 8e-61 tr|A1UIR6|A1UIR6_MYCSK Tax_Id=189918 SubName: Full=Acyl transfer... 240 8e-61 tr|A4F5D7|A4F5D7_SORCE Tax_Id=56 (spiE)SubName: Full=Polyketide ... 175 3e-41 tr|Q53840|Q53840_SORCE Tax_Id=56 (sorB)SubName: Full=Soraphen po... 171 5e-40 tr|Q3S864|Q3S864_9ACTO Tax_Id=42238 SubName: Full=Nodular polyke... 170 8e-40 tr|Q8GBX7|Q8GBX7_SORCE Tax_Id=56 (spiG)SubName: Full=Polyketide ... 166 2e-38 tr|A4F5C6|A4F5C6_SORCE Tax_Id=56 (spiG)SubName: Full=Polyketide ... 166 2e-38 tr|Q8GBX6|Q8GBX6_SORCE Tax_Id=56 (spiH)SubName: Full=Polyketide ... 166 2e-38 tr|A4F5C7|A4F5C7_SORCE Tax_Id=56 (spiH)SubName: Full=Polyketide ... 166 2e-38 tr|Q0RIF5|Q0RIF5_FRAAA Tax_Id=326424 SubName: Full=Putative type... 165 3e-38 tr|C9YYI1|C9YYI1_STRSW Tax_Id=680198 SubName: Full=Putative type... 165 3e-38 tr|Q0QMN7|Q0QMN7_9ACTO Tax_Id=358765 SubName: Full=Polyketide sy... 164 5e-38 tr|B5L6M3|B5L6M3_MICCH Tax_Id=1874 SubName: Full=Putative type I... 164 5e-38 tr|C1B9P9|C1B9P9_RHOOB Tax_Id=632772 SubName: Full=Polyketide sy... 164 6e-38 tr|D0LQW2|D0LQW2_HALO1 Tax_Id=502025 SubName: Full=KR domain pro... 164 6e-38 tr|D0LQW1|D0LQW1_HALO1 Tax_Id=502025 SubName: Full=6-deoxyerythr... 164 6e-38 tr|D0LQW0|D0LQW0_HALO1 Tax_Id=502025 SubName: Full=Acyl transfer... 164 6e-38 tr|B6ZK65|B6ZK65_9ACTO Tax_Id=324833 (lsd12)SubName: Full=Putati... 162 2e-37 tr|B5M9K9|B5M9K9_9ACTO Tax_Id=324833 (lasAII)SubName: Full=Lasal... 162 2e-37 tr|Q30CS2|Q30CS2_STRAU Tax_Id=1894 (lipPks1)SubName: Full=LipPks... 161 4e-37 tr|Q93HJ2|Q93HJ2_STRAW Tax_Id=33903 (olmA6)SubName: Full=Modular... 160 7e-37 tr|Q93HJ1|Q93HJ1_STRAW Tax_Id=33903 (olmA7)SubName: Full=Modular... 160 7e-37 tr|Q1L0T0|Q1L0T0_STRHY Tax_Id=285527 SubName: Full=GelC;[Strepto... 160 7e-37 tr|Q0S8W4|Q0S8W4_RHOSR Tax_Id=101510 SubName: Full=Type I polyke... 160 9e-37 tr|B4ER95|B4ER95_STRON Tax_Id=67339 (norA')SubName: Full=Protein... 160 9e-37 tr|Q0RMN9|Q0RMN9_FRAAA Tax_Id=326424 SubName: Full=Putative type... 160 1e-36 tr|B3TMP1|B3TMP1_9ACTO Tax_Id=46161 SubName: Full=Polyketide syn... 159 2e-36 >tr|B2HM91|B2HM91_MYCMM Tax_Id=216594 (mbtD)SubName: Full=Polyketide synthase MbtD;[Mycobacterium marinum] Length = 1024 Score = 1758 bits (4554), Expect = 0.0 Identities = 907/1024 (88%), Positives = 908/1024 (88%) Query: 1 VSAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXX 60 +SAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLF Sbjct: 1 MSAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFRTRAARRH 60 Query: 61 XXXXXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYE 120 TRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVF LFYE Sbjct: 61 RALAMVRTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFPGQGGQRPGMGQLFYE 120 Query: 121 SVPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSF 180 SVPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSF Sbjct: 121 SVPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSF 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIR DRETC Sbjct: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRAHAADEFAAADYAMAIVAADRETC 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH Sbjct: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA Sbjct: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA Sbjct: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 Query: 421 QLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXXX 480 QLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQ Sbjct: 421 QLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQPPSVSVAPA 480 Query: 481 XXXXXXXXXXXXXXRLLVEEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXXXXX 540 RLLVEEWVRLSQRSLTPPRVVGIVDPTG Sbjct: 481 APSVPDATADTTPARLLVEEWVRLSQRSLTPPRVVGIVDPTGACAQLATAMTAAAHQAGA 540 Query: 541 XXRVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTDCWL 600 RVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTDCWL Sbjct: 541 TARVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTDCWL 600 Query: 601 VTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAAL 660 VTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAAL Sbjct: 601 VTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAAL 660 Query: 661 HTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNLGLEFCDHFAHRGA 720 HTANEPELAYRDGAFYAKRI CPEHVLIIGGTGNLGLEFCDHFAHRGA Sbjct: 661 HTANEPELAYRDGAFYAKRIVAGEGAVVHGAGACPEHVLIIGGTGNLGLEFCDHFAHRGA 720 Query: 721 RRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIH 780 RRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIH Sbjct: 721 RRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIH 780 Query: 781 AAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQV 840 AAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQV Sbjct: 781 AAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQV 840 Query: 841 MYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIA 900 MYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIA Sbjct: 841 MYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIA 900 Query: 901 LGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPAEPADLPGRLSNXX 960 LGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPAEPADLPGRLSN Sbjct: 901 LGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPAEPADLPGRLSNLL 960 Query: 961 XXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQ 1020 DTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQ Sbjct: 961 AAAIGAERAERIDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQ 1020 Query: 1021 LGSR 1024 LGSR Sbjct: 1021 LGSR 1024 >tr|A0PTV2|A0PTV2_MYCUA Tax_Id=362242 (mbtD)SubName: Full=Polyketide synthase MbtD;[Mycobacterium ulcerans] Length = 1024 Score = 1737 bits (4499), Expect = 0.0 Identities = 898/1024 (87%), Positives = 902/1024 (88%) Query: 1 VSAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXX 60 +SAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLF Sbjct: 1 MSAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFRTRAARRH 60 Query: 61 XXXXXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYE 120 TRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVF LFYE Sbjct: 61 RALAMVRTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFPGQGGQRPGMGQLFYE 120 Query: 121 SVPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSF 180 SVPAFRAEVDRCAQAFEAQ+CGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSF Sbjct: 121 SVPAFRAEVDRCAQAFEAQACGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSF 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 I PNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIR DRE C Sbjct: 181 DIPPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRAHAADEFAAADYAMAIVAADREAC 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH Sbjct: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDY FWNLRNIVRFDKAIA Sbjct: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYCFWNLRNIVRFDKAIA 360 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA Sbjct: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 Query: 421 QLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXXX 480 QLAVHDLNYPWECLRAEPDGAQALP+LDFPNTRMNEIRLWLPYDEVLPRRQ Sbjct: 421 QLAVHDLNYPWECLRAEPDGAQALPMLDFPNTRMNEIRLWLPYDEVLPRRQPPSVSVAPA 480 Query: 481 XXXXXXXXXXXXXXRLLVEEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXXXXX 540 RLLVEEWVRLSQRSLTPPRVVGIVDPTG Sbjct: 481 APSVPDATADTTPARLLVEEWVRLSQRSLTPPRVVGIVDPTGACAQLATAMTAAAHQAGA 540 Query: 541 XXRVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTDCWL 600 RVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTDCWL Sbjct: 541 TARVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTDCWL 600 Query: 601 VTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAAL 660 VTVGGEAATAADGPPDPVHAAASAGFRSIGAEHP VGFRHLDLPAGATAQDWAHPIVAAL Sbjct: 601 VTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPDVGFRHLDLPAGATAQDWAHPIVAAL 660 Query: 661 HTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNLGLEFCDHFAHRGA 720 HTANEPELAYRDGAFYAKRI CPEHVLIIGGTGNLGLE CDHFAHRGA Sbjct: 661 HTANEPELAYRDGAFYAKRIVAGEGAVVHGAGACPEHVLIIGGTGNLGLESCDHFAHRGA 720 Query: 721 RRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIH 780 RRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIH Sbjct: 721 RRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIH 780 Query: 781 AAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQV 840 AAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQV Sbjct: 781 AAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQV 840 Query: 841 MYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIA 900 MYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIA Sbjct: 841 MYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIA 900 Query: 901 LGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPAEPADLPGRLSNXX 960 LGMQRLGRNAIVAAF+FDRARPVLETFGYGPLVSELLSPVSETAAPAEPADLPGRLSN Sbjct: 901 LGMQRLGRNAIVAAFNFDRARPVLETFGYGPLVSELLSPVSETAAPAEPADLPGRLSNLL 960 Query: 961 XXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQ 1020 DTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQ Sbjct: 961 AAAIGAERAERIDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQ 1020 Query: 1021 LGSR 1024 LGSR Sbjct: 1021 LGSR 1024 >tr|B1MPE9|B1MPE9_MYCA9 Tax_Id=561007 SubName: Full=Putative polyketide synthase MbtD;[Mycobacterium abscessus] Length = 1010 Score = 913 bits (2359), Expect = 0.0 Identities = 495/1011 (48%), Positives = 621/1011 (61%), Gaps = 19/1011 (1%) Query: 24 LLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAELIDALQAMIDRY 83 +L EA+AL +VA HP + P I+ M+F +L+ AL+ ++ Sbjct: 1 MLRREASALLAYVADHPRIAPNRIAGMIFRTRVARRYRALATVENHDQLVAALRTVVAGT 60 Query: 84 EHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRCAQAFEAQSCGS 143 EHP ++R A RR G+VF LFY++ P+FRAEV+RCA F+ Q S Sbjct: 61 EHPLVVRNSEPATARRHGFVFPGQGGQRPGMGRLFYDAFPSFRAEVERCADLFDKQFGRS 120 Query: 144 PRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNVTIGHSQGEVAAAYVSGT 203 P +YLLD + SA +VQPALFTQM LAA+WR+ G+ P +GHSQGE+A AYVSG Sbjct: 121 PLSYLLDDQLPTNDSATVVQPALFTQMVGLAALWRTVGVTPRAVVGHSQGEIAGAYVSGV 180 Query: 204 ITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCSGWAQLSVVNSPRMVG 263 ++L+DAV V+G R DR+TCE+LLAR SGWA+LSV+NSP MVG Sbjct: 181 MSLDDAVTVVGTRAGIADEFPADDYAMAVIATDRDTCEELLARNSGWAELSVINSPSMVG 240 Query: 264 ISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLRAAIQDQLQHPSFVDTD 323 ISG+RETV IV+ L E G FARVI VRYPAHTS+I ++R A+ + L F ++ Sbjct: 241 ISGQRETVHQIVEHLIEDGVFARVIPVRYPAHTSMIASIGAQIRHALTENLDAGEFTVSE 300 Query: 324 IDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDVETFVELAEHPTLQLAI 383 IDC+GATLG I+ E+PV YWFWNLRN VRFD+A+A A V+TFVELAEHPTLQLA+ Sbjct: 301 IDCIGATLGTAISPEMPVDQYWFWNLRNAVRFDRAVATAAAAHVDTFVELAEHPTLQLAL 360 Query: 384 HENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHDLNYPWECLRAEPDGAQA 443 ENLAAL E R A VVGTS R ATDLGEFT NLA++AVHDL+Y W+ LR E + Sbjct: 361 RENLAALGSE---RTACVVGTSHRNATDLGEFTANLAKIAVHDLDYNWDALRTEAPDRVS 417 Query: 444 LPLLDFPNTRMNEIRLWLPYDE-----VLPRRQXXXXXXXXXXXXXXXXXXXXXXXRLLV 498 LPL DFPN + N+I LWL Y +P++ RLL Sbjct: 418 LPLRDFPNVQNNDIPLWLSYRADTSGVAVPKQPIVTPEAERRVEMGNDSRAYP---RLLR 474 Query: 499 EEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXXXXXXXRVVNGENDGTGADVNT 558 E W ++++RS+ PPR +D TG R+V G ++ D +T Sbjct: 475 EAWAKVTRRSMMPPRSYAFIDGTGDAGALVEALRDSAPNFGSSARIVTGTDESGIGDADT 534 Query: 559 LVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTDCWLVTVGGEAATAADGPPDPV 618 +VI+LP LD AA V FF NR WWP + + VT CWLVTVGGE A A DGP PV Sbjct: 535 VVIVLPSPALLDDHEAADAVARFFGNRTWWPRLSSTVTGCWLVTVGGEQAIADDGPAHPV 594 Query: 619 HAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAALHTANEPELAYRDGAFYAK 678 HAA +AGFR +G EHPG+ FRHLDL + + D A I+AAL +A E ELA R YAK Sbjct: 595 HAAIAAGFRCMGTEHPGIAFRHLDLTSDIASPDKADNILAALQSAGESELALRADGMYAK 654 Query: 679 RIXXXXXXXXXXXXX-CPEHVLIIGGTGNLGLEFCDHFAHRGARRITLVSRSGESAAVAE 737 R+ P HV+I GGTG LG EFC+H+A G R+ITL+SRSGE+ AV Sbjct: 655 RVLDIDQDGDESSRVVAPAHVVITGGTGKLGQEFCEHYARMGTRQITLISRSGETDAVTG 714 Query: 738 RLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIHAAVAYASVEFSDITTDD 797 RL +R +T A++ CDV D AAV+ LA Q R TPADLI+HAAV Y+ S++TT+ Sbjct: 715 RLDAIRRSTGAKVRALPCDVTDTAAVTALADQLRDTPADLIVHAAVDYSDTPLSEVTTNK 774 Query: 798 ADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLR 857 +AL AKV+GI VLD PRTD CR++LCSS ATIGG+GQ+MYAA NRMLD +A R Sbjct: 775 FQDALRAKVIGISNVLDTVPRTDSCRVMLCSSLAATIGGKGQLMYAAGNRMLDVLASTRR 834 Query: 858 AEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDF 917 A GLDC S+QWGQWTVH DL + +A+LAA GV PM PA+A+A+GM N +V AFD Sbjct: 835 ASGLDCTSIQWGQWTVHLDLGDAGIAKLAAAGVHPMRPADALAVGMGHHHGNTLVGAFDL 894 Query: 918 DRARPVLETFGYGPLVSEL------LSPVSET-AAPAEPADLPGRLSNXXXXXXXXXXXX 970 +AR +L FGYGPL+SEL ++P T AP + G L Sbjct: 895 TQARAMLGVFGYGPLLSELEDNGGPVAPAETTRPAPVVSENRSGHLVQLLAEVIGADHAD 954 Query: 971 XXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQL 1021 DT++PMVA+GLDSLQALE RRRV+AE D EL V DLLGGAS+ V+ L Sbjct: 955 SIDTAMPMVAMGLDSLQALEFRRRVQAELDFELPVQDLLGGASVDHVIDAL 1005 >tr|Q5Z1T1|Q5Z1T1_NOCFA Tax_Id=37329 (nbtC)SubName: Full=Putative polyketide synthase;[Nocardia farcinica] Length = 1028 Score = 749 bits (1933), Expect = 0.0 Identities = 439/1037 (42%), Positives = 579/1037 (55%), Gaps = 38/1037 (3%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 ++Y LPDGT+PVL+S+DT + + +EA A+ ++ HP ++P ++ MLF Sbjct: 2 SSYLLPDGTVPVLISSDTADGVRAEAAAVLAYLDEHPRVSPERVAEMLFRTRVARRYRAL 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 TR EL+D L+A++ ++ D AA RRIG+VF L+Y+ Sbjct: 62 AMVRTREELLDGLRAVVADTPSRVVVTGDGAASARRIGFVFPGQGSQRPGMGRLYYDVSD 121 Query: 124 AFRAEVDRCAQAF-EAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGI 182 A+RA VD CA E P +YLL + + VQPAL M LAAMWR+ G+ Sbjct: 122 AYRAAVDACAAIHRERFEHDQPLHYLLGDEGRYQDTVWEVQPALMFHMYGLAAMWRAAGV 181 Query: 183 APNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCED 242 P T+GHSQGE+AA VS +TL D+V + R DRE CE Sbjct: 182 EPAATVGHSQGELAAGAVSAVMTLRDSVLAVTHRARLVERISPRGYSMAVLGMDREECEA 241 Query: 243 LLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDG 302 LLAR SGWA+LSVVN+P ++ ISG+R+T+ +V+ T G FAR I+V YPAHTS++ + Sbjct: 242 LLARHSGWAELSVVNAPHILAISGDRDTIVDMVELATARGQFAREIKVSYPAHTSIVAEL 301 Query: 303 ADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAA 362 + + + D++ F ++I C GATLGA IT +L DYW+WNLRN VRFD+A+ AA Sbjct: 302 REHFMSFLGDEMSGECFTASEIPCYGATLGAAITPDLTHRDYWYWNLRNRVRFDRAVVAA 361 Query: 363 VQRDVETFVELAEHPTLQLAIHENLAALRDEADD--RPAMVVGTSERTATDLGEFTRNLA 420 V V+T +E+AEHP LQLA+ ENL + E R V+GTS RTA L EFTRNLA Sbjct: 362 VTDGVDTLIEVAEHPVLQLALQENLTLVPREKLPLGRDVKVLGTSLRTAEGLAEFTRNLA 421 Query: 421 QLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXXX 480 +AVHDL+Y W+ LR + A PL DFP+T M+ RLW D LP + Sbjct: 422 TIAVHDLDYRWDALRTDDGAAPRPPLRDFPHTIMHPRRLWAGPD--LPAAEPQPDAAPAP 479 Query: 481 XXXXXXXXXXXXXXRLLVEEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXXXXX 540 LVE W+ L +RS+ PR + +VD TG Sbjct: 480 ER--------------LVETWIPLDKRSMLAPRTLAVVDHTGRCAELADALVAAADRHGA 525 Query: 541 XXRVVNGEN-DGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDT--GVTD 597 V++ G + +T V+LLPE P DG AA + FF++R W P +D Sbjct: 526 TATVLDAAALAGDLPEFDTAVVLLPELPDTDGAAALDDFAAFFADRTWVPALDRLGPGGQ 585 Query: 598 CWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIV 657 CWLVT GGE+ A D P H A +AG+RS G E PG+ RHLDL AGA D A IV Sbjct: 586 CWLVTTGGESVLADDPVPHLFHGAVAAGYRSAGIERPGILLRHLDLAAGA-GPDQAARIV 644 Query: 658 AALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNLGLEFCDHFAH 717 A+HTA E ELA R G Y KR+ HVLI+GGTG LGL FC+HFAH Sbjct: 645 TAVHTAGECELALRGGKLYVKRLVVDPATDASAADTDLSHVLIVGGTGQLGLRFCEHFAH 704 Query: 718 RGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADL 777 GA R+TLVSRSGE+ VA L +LR +I V CDV D AV R AA S P L Sbjct: 705 AGAGRVTLVSRSGETERVAGELNRLRRLGGTEIVVEACDVSDAEAVKRFAATIESAPVSL 764 Query: 778 IIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGR 837 +IHAAV Y E DIT + A +KV+G+G VLD P T+ RI+LCSS AT+ GR Sbjct: 765 LIHAAVNYVDAELPDITAEMVTEAAGSKVLGLGTVLDIVPFTEQQRILLCSSTAATLSGR 824 Query: 838 GQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAE 897 GQ++YA NRMLD +A RLRA+G D +S++WG W+V LD + A++A GV PM P + Sbjct: 825 GQILYAVTNRMLDILARRLRAQGRDAISIEWGLWSVAGPLDEAGFARVADAGVHPMAPRD 884 Query: 898 AIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVS---------------E 942 AI G+ +A++ + D+ R VL+TFG G ++ E+ +P + + Sbjct: 885 AITAGLAGPWGDAMIMSADWAFLREVLDTFGQGSVLPEIATPAAASAPEPDVAEPVVTEQ 944 Query: 943 TAAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHE 1002 AAPA L R+ D SVP+VALGLDSLQAL+ R+RVKAE D + Sbjct: 945 PAAPAADRPLAERMLTQLHKVMGTDGSESIDGSVPLVALGLDSLQALDFRKRVKAELDRD 1004 Query: 1003 LEVSDLLGGASIADVLA 1019 L V+ +LGGAS+ DV+A Sbjct: 1005 LPVAAILGGASLDDVVA 1021 >tr|D0L269|D0L269_GORB4 Tax_Id=526226 SubName: Full=Acyl transferase;[Gordonia bronchialis] Length = 1560 Score = 740 bits (1910), Expect = 0.0 Identities = 447/1059 (42%), Positives = 579/1059 (54%), Gaps = 52/1059 (4%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A RLPDGT PV++SADTP LL +E +L D++ P ++P +S MLF Sbjct: 2 ATLRLPDGTSPVVVSADTPALLRAEGASLADYLTRAPHVSPDQLSRMLFRSRPVRRFRAL 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 A L++ L+A+ +HPA++R+D A R RI VF L++ Sbjct: 62 VSARDAAALVEGLRAVATGTDHPAVVRSDGPARRSRIALVFPGQGGQRPGMGALYHRHSA 121 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLD----KNFQDDGSAGIVQPALFTQMAALAAMWRS 179 AF AEV+R FE + SPR+YLLD ++ D +A ++QPALF QMAALAAMWRS Sbjct: 122 AFAAEVERLHAVFEEVAGCSPRSYLLDDDPDRDTSADDTAALIQPALFMQMAALAAMWRS 181 Query: 180 FGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRET 239 FG+ P + +GHSQGE+AA YV+G + L DA+ V+ R DR Sbjct: 182 FGVVPEIVVGHSQGEIAACYVAGVMDLHDAITVLTTRARSVDTTASQQYSMAVLDTDRAE 241 Query: 240 CEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLI 299 E LLAR SGWA++SV+NSPRM G+SG+ + +VD L E G F+RVI VRYPAHT+++ Sbjct: 242 AESLLARRSGWAEISVINSPRMTGVSGDTPIITSVVDQLAEAGRFSRVIAVRYPAHTAVM 301 Query: 300 HDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAI 359 H+ A + A ++L F T I C+G+TLG IT +LP+G+YWFWNLRN+VRFDKA+ Sbjct: 302 HEVARTILDATGERLSDKGFTATPITCIGSTLGEEITPDLPLGEYWFWNLRNVVRFDKAV 361 Query: 360 AAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNL 419 A AV TFVEL+EHPTLQL I E L ++ D A VVGTS R A D+ RNL Sbjct: 362 ARAVALGANTFVELSEHPTLQLPIGETLESIADAT----ATVVGTSRRQAEDMSVIARNL 417 Query: 420 AQLAVHDLNYPWECLRAEPD---GAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXX 476 +AV DL++ W L E D G+ ALPL DFP+T N+ LW+ Y P Sbjct: 418 VLIAVGDLDFDWTSLLVEDDTARGSAALPLPDFPHTITNDSFLWMTYATNRPE----VSP 473 Query: 477 XXXXXXXXXXXXXXXXXXRLLVEEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXX 536 + + WVR+ +RS+ P+ +GIVD Sbjct: 474 PHAGTSAPATPAAVPDPTMTVAQRWVRIPRRSMVAPQTMGIVDLGALPGLADAIVEHAPD 533 Query: 537 XXXXXXRV---VNGENDGTGAD-VNTLVILLP---ETPKLDGRA--AAAEVGGFFSNRAW 587 R+ +D T D V+T+V+L P P+ D R A + FF R W Sbjct: 534 FGAAARRIDVAAESSDDATLLDGVDTVVVLGPAGAREPRADARTREAIGQAADFFGERRW 593 Query: 588 WPGVDTGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDL-PA- 645 W D D WLVTVGGEA T + P+ A +AGFR +GAE+P F HLDL PA Sbjct: 594 WSAADP-PRDHWLVTVGGEAVTDNES-PEIGAAGIAAGFRCLGAEYPNASFGHLDLDPAL 651 Query: 646 ---GATAQDWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHVLIIG 702 G A IVAALH A EP++A R + KR+ HVLI G Sbjct: 652 LETGTVDAAVADKIVAALHIAREPDIALRGKDLFVKRLTPADDTATAETPAAGRHVLITG 711 Query: 703 GTGNLGLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAA 762 GTG +GLEF DHFA +G R+TLVSR G + V RL LR ++ V RCD+ D A Sbjct: 712 GTGKVGLEFADHFAAQGVTRLTLVSRRGATPEVQRRLDALR-RNGTEVVVQRCDITDDAQ 770 Query: 763 VSRLAAQHRSTPADLIIHAAV----AYASVEFSDITTDDADNALYAKVVGIGQVLDAFPR 818 V L P D+ IHAA + DIT D AKV G+ ++L A P Sbjct: 771 VRALGESLADAPVDVAIHAAADLPPGTGGIGLEDITGDVVSRLCDAKVAGVHRILGAVPT 830 Query: 819 TDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLD 878 +D R++LCSS ATIGGRG ++Y+AANRMLDA+A LRA+G+DC SVQWGQW VH Sbjct: 831 SDDVRVLLCSSFAATIGGRGTIVYSAANRMLDAVATALRADGVDCASVQWGQWAVHDGSG 890 Query: 879 ASSMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLS 938 A+ A LAA+G MP AI G+ + NAIVAAFD+ R VL FGYGPL+S+L S Sbjct: 891 AADAATLAAVGYRTMPSESAIRAGL-AVRHNAIVAAFDWQRGHEVLRDFGYGPLLSDLAS 949 Query: 939 -----------PVSET----AAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGL 983 P +++ AAP DL DT+ P+VALGL Sbjct: 950 AEPAPPRPSTRPAADSTPGPAAPQPVRDLRTAALAVVADVIGAADVDAIDTTRPLVALGL 1009 Query: 984 DSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQLG 1022 DSLQAL+LRR+V +F +EL V++L+GGAS+ DV A LG Sbjct: 1010 DSLQALDLRRKVTEQFGYELPVTELVGGASLDDVTALLG 1048 Score = 69.7 bits (169), Expect = 2e-09 Identities = 54/137 (39%), Positives = 68/137 (49%), Gaps = 30/137 (21%) Query: 918 DRARPVLETFGYGPLVSELL-----------------SPVSE----------TAAPAE-- 948 D R V E FGY V+EL+ +PVS T PA Sbjct: 1016 DLRRKVTEQFGYELPVTELVGGASLDDVTALLGQHAATPVSTESNSSEPTWPTTGPATTA 1075 Query: 949 PADLPG-RLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSD 1007 P PG R+ DT+ P+VALGLDSLQAL+LRR+V EF +EL V++ Sbjct: 1076 PTVSPGQRIPALVAEVIGATDVDAIDTTRPLVALGLDSLQALDLRRKVTEEFGYELPVTE 1135 Query: 1008 LLGGASIADVLAQLGSR 1024 L+GGAS+ DV+A LG R Sbjct: 1136 LVGGASLDDVIALLGDR 1152 >tr|C2AVC9|C2AVC9_TSUPA Tax_Id=521096 SubName: Full=Putative polyketide synthase component;[Tsukamurella paurometabola DSM 20162] Length = 1042 Score = 494 bits (1272), Expect = e-137 Identities = 370/1061 (34%), Positives = 490/1061 (46%), Gaps = 92/1061 (8%) Query: 8 LPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXX 67 LPDG +LSAD + L + A LR ++ HP + ++A L Sbjct: 25 LPDGLPAFVLSADGADSLAAAAAQLRRYLTEHPQVPLPAVAAALVATRDLRRHRAIVHTD 84 Query: 68 TRAELIDALQAMIDRYEHPAL-----IRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESV 122 R EL+ AL A+ P + T AA +VF LF+ Sbjct: 85 DRGELVTALDALAADPVRPVGTAVPGLHTGVAAAGAP-AFVFPGQGSQRRGMGALFHRES 143 Query: 123 PAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGS----AGIVQPALFTQMAALAAMWR 178 +R V++ S R+YLL + G +VQPA+F Q LAAMWR Sbjct: 144 AVYRDTVEKIHAIALEVFGSSARDYLLGTGEWEQGGRPVPVEVVQPAIFMQALGLAAMWR 203 Query: 179 SFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRE 238 + GI P + +GHSQGE+AAA +GT+ L D +R++ R DRE Sbjct: 204 AAGIEPRIHVGHSQGEIAAAVAAGTVGLADGLRLVTRRALAVRDNAPTGHSMAVLGTDRE 263 Query: 239 TCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSL 298 C +LAR G+A+LSVVNS ++ +SGER+ V G+V TE G FAR IRV YPAHTSL Sbjct: 264 RCAAMLARTVGFAELSVVNSAHVLCVSGERDVVAGLVAQATERGIFAREIRVEYPAHTSL 323 Query: 299 IHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKA 358 + LR + HP+F+ T+ +G TLG + ++ DYWFWNL+N VRFD A Sbjct: 324 V-GSMWHLREKWMGVMDHPAFLPTEHLLIGGTLGEAVPADTDFLDYWFWNLKNPVRFDLA 382 Query: 359 IAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRN 418 AA+ + +ELAEHPTLQLA+HEN+A +A R A V G+S R ATDL EF+ Sbjct: 383 TRAALDAGADRLIELAEHPTLQLALHENIA----DAGAR-ATVTGSSRRDATDLSEFSSA 437 Query: 419 LAQLAV---HDLNYPWECLRAE-PDGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXX 474 +A + V DL+ + E P G FP ++ RLW LP R Sbjct: 438 VADVLVTHARDLDVQRTLVAEELPPG--------FPAAPLSRQRLW----AALPGR---- 481 Query: 475 XXXXXXXXXXXXXXXXXXXXRLLVEEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXX 534 R+L W L PPR + I+DPTG Sbjct: 482 ---------PATAGPVRPRTRVLDTVWTDLDAPVSAPPRPLAIIDPTGAHADLAAALLDA 532 Query: 535 XXXXXXXXRVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTG 594 R +D G D V+L+P + + D AA VG ++R WW GV Sbjct: 533 AARYGTPAR----RSDRAGDD-EIAVVLVPGSAETDTTIAA--VGELLADRRWWAGVQP- 584 Query: 595 VTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAH 654 VT G A AD PD AA + GFR+ GA+ PGV RHLDL A A A Sbjct: 585 AAGIAAVTAGAVVADPADPGPDGAAAAIAVGFRAFGADLPGVEVRHLDLDPRADAAAQAG 644 Query: 655 PIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXC-----PEHVLIIGGTGNLGL 709 + ALH A EP LA R GA A+R +V+I GGTG+LGL Sbjct: 645 TAIHALHVAGEPRLALRSGAVRAERWVDAEPTETGTEPPAGLLETARNVVISGGTGHLGL 704 Query: 710 EFCDHFAHRGARRITLVSRSGESAAVAERLAQL-RSATAAQIAVTRCDVGDPAAV-SRLA 767 F H A GA +TL+SRSG V LA++ R A + V CDV DPAAV + LA Sbjct: 705 AFAAHAAAHGAASVTLLSRSGGGTTVRHALARIARRHPACAVTVVPCDVTDPAAVATALA 764 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 R+ DL++HAAV Y +D+ D A AKV G+ + A P ++ C Sbjct: 765 GAGRA--IDLVVHAAVGYRRCAATDLDASDFTAAAAAKVGGLRTLAQAVP---DATLLTC 819 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAA 887 SSA A + G GQ YAA+N + +A A LR G +V+WG W LD + A + A Sbjct: 820 SSAAAALPGAGQAWYAASNTLAEAEAAALRRAGRRAAAVRWGLWEQAGPLDEAGFAAVTA 879 Query: 888 IGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLS------PVS 941 GVIP+ +A+A + G ++ A D R R V FG L+++L P Sbjct: 880 AGVIPLAAPDALAALARSTGPEPVITAVDLPRLRDVAAAFGAAALLTDLTEDTTPAVPAP 939 Query: 942 ETAAPAEPADLPGRLS---------------------NXXXXXXXXXXXXXXDTSVPMVA 980 A P D P ++ D V +VA Sbjct: 940 SDAVPGTAPDAPATVTVTTDAAPGPAPGGGADVAAVLRHHLARALAVPADTLDPDVALVA 999 Query: 981 LGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQL 1021 LGLDSLQALELR V+ E D EL + +LGGA++A+V A L Sbjct: 1000 LGLDSLQALELRTAVRDELDAELPLEAILGGATLAEVSATL 1040 >tr|A1TBS7|A1TBS7_MYCVP Tax_Id=350058 SubName: Full=Acyl transferase domain protein;[Mycobacterium vanbaalenii] Length = 972 Score = 409 bits (1052), Expect = e-112 Identities = 324/1035 (31%), Positives = 454/1035 (43%), Gaps = 84/1035 (8%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 +A RLPDG + V LSA L+ + A + H+ +P PG ++A L Sbjct: 2 SAGRLPDGRVAVPLSAHHEALVSATARDILGHLQRNPS-EPGQVAAQLVRTRRLRRHRAI 60 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL LQA+ D +HP + R+ A R +VF Y +P Sbjct: 61 VRAGDRDELAAGLQAVADDRDHPLVARSAGRA-GARTAFVFPGQGSQWPGMGGEAYRLLP 119 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIA 183 +RAE DR +AF A SP +L + S +Q A F ALAA+WRS GI Sbjct: 120 VYRAEADRLTEAFLAAGLTSPLPFLTADTDGEPVSQYDLQAAQFVHSVALAAVWRSCGIV 179 Query: 184 PNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDL 243 P++T+GHS GEVAAAYV+ T+TL DAV V+ R E E L Sbjct: 180 PDLTVGHSLGEVAAAYVAETVTLVDAVTVLAARAAAIEAIPGDNGVAVLGVDATEAAE-L 238 Query: 244 LARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGA 303 +A GW +LS VN+ V +SGER V I G FA+ + + +PAHT+ + Sbjct: 239 IAATGGWLELSAVNAQNSVAVSGERSAVAAIAAAARARGRFAKELAMSFPAHTTAMETQR 298 Query: 304 DKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAV 363 ++L + + F D+ + +G+ G + + G YW+ NLRN +RFD+A+ A+ Sbjct: 299 EQLVRRLPTSV----FADSPVQFVGSATGQLVRAGTEFGAYWYANLRNTIRFDQAVQTAI 354 Query: 364 QRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLA 423 +VEL+ HP+L A+ + + + A A++VG+ R + + N+ A Sbjct: 355 GLGAGVYVELSAHPSLLFAVEDGIERVGAAA----AVLVGSGHRDESVPDRLSANIVTAA 410 Query: 424 VHDLNYPW-ECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXXXXX 482 D Y W + L EP+ PL FP M LW E LP Sbjct: 411 AADPAYRWGDLLTGEPE-----PLFGFPGAPMRAEHLWAE-PEPLP-------------- 450 Query: 483 XXXXXXXXXXXXRLLVEEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXXXXXXX 542 + E W R P RV V Sbjct: 451 -------VAPGLTVTTETW-----RQRRPRRVSAKVSRRVAVIESGSGTAISRSLRQAID 498 Query: 543 RVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVT------ 596 R + G AD + +++ P D E+ G +DTG+ Sbjct: 499 RRADLSVAGA-ADADLAIVVAPTFAGADAAGCVNELSG---------AIDTGLLGYADTF 548 Query: 597 -----DCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQD 651 D WLVTVG E TA D PD A +A R IG EHP F HLDLPAGAT D Sbjct: 549 GPRCRDVWLVTVGAENVTAEDPAPDLGQAGVAALHRCIGFEHPDQSFHHLDLPAGAT--D 606 Query: 652 WAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCP--EHVLIIGGTGNLGL 709 + + A E L RDG Y + + ++V+I GG+G +GL Sbjct: 607 ALGAVDVMVDGAGELALR-RDGQVYERTLGDDTSTAPPWDLSSGTLDNVVITGGSGAIGL 665 Query: 710 EFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQ 769 F A RGARRI L+SR G A + L A+I CD+ DP ++ A+ Sbjct: 666 SFARFLAARGARRIVLLSRRGAGPAPLDNLG-------AEIIAPACDLRDPRQLAATVAE 718 Query: 770 HRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSS 829 PA LIIHAA +DIT + AK++G+ + +P D RI+LCSS Sbjct: 719 FAGGPASLIIHAAGTATFANRADITGAALADMAGAKIIGLEALTRTWPIRDDARILLCSS 778 Query: 830 ARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIG 889 GG+G YAAANRMLD MA RL A+G +C +V++G W +DA+ +A++ G Sbjct: 779 VTGVWGGKGVGGYAAANRMLDVMAARLGADGRNCTAVRFGLWEGSGIVDAAEIARVERTG 838 Query: 890 VIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPAEP 949 + M P A+ + R+ +V A D DR R FG P+ E A PA Sbjct: 839 LRQMKPELAVEASLCDFPRDPLVLAADRDRMRMF---FGEKPV--EKPGEADTGAGPASM 893 Query: 950 ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLL 1009 A P D P+ LG+DSL AL+LR+R+K H + ++ LL Sbjct: 894 A--PPDAVRTQLAAVLDVDAAALDLDSPLFDLGVDSLLALDLRKRLKRLTGHTVPLATLL 951 Query: 1010 GGASIADVLAQLGSR 1024 GG + AD++A L + Sbjct: 952 GGITGADLIAGLSEK 966 >tr|Q73XY4|Q73XY4_MYCPA Tax_Id=1770 (mbtD)SubName: Full=MbtD;[Mycobacterium paratuberculosis] Length = 1013 Score = 401 bits (1030), Expect = e-109 Identities = 316/1036 (30%), Positives = 454/1036 (43%), Gaps = 87/1036 (8%) Query: 8 LPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTP--GPISAMLFXXXXXXXXXXXXX 65 LPDG IPVLLS+ PEL+ +A A+ +++ + T G ++A L Sbjct: 7 LPDGRIPVLLSSHDPELIRRDAAAILEYLDRIGESTEATGAVAATLLRLRRVRRHRALLR 66 Query: 66 XXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAF 125 RAEL L A+ EH ALI RI +VF Y +PA+ Sbjct: 67 AADRAELAAGLGAIARGEEH-ALITRSARTTPPRIAFVFPGQGNQWQAMGADAYRLLPAY 125 Query: 126 RAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPN 185 R DRCAQAF + SP YL+ + Q + +Q A FT ALA WR FG+ P Sbjct: 126 REAADRCAQAFVSAGFPSPLPYLVSPDEQS-WTRPEIQGAQFTHAVALAEAWRCFGVLPE 184 Query: 186 VTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLA 245 +TIGHS GEVAAAYV+ I+L DAV ++ R + E LLA Sbjct: 185 ITIGHSLGEVAAAYVAEAISLPDAVALVVARATVVDRLTGRYAMAVLGTGAAD-AESLLA 243 Query: 246 RCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADK 305 GW ++S VN P ++G+ + V V + FA + V YP HTS + Sbjct: 244 TTPGWVEVSAVNGPASTVVAGDHDAVAAAVRLARQREIFAHQLFVDYPGHTSALR----P 299 Query: 306 LRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQR 365 LRAA+ + +F D+ I +G+T GA + + YW+ NL + VRFD A+ A Sbjct: 300 LRAALAELTPQSAFRDSPIRFIGSTRGAEVAATTDYASYWYENLCSTVRFDLAVQCARSC 359 Query: 366 DVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVH 425 + FVEL+ HP+L L L DD A++VG+ R + ++A +A Sbjct: 360 GADAFVELSAHPSL-------LYPLSGIIDDESAVIVGSGHRDRPITESLSASMAAVATA 412 Query: 426 DLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYD---EVLPRRQXXXXXXXXXXX 482 D Y W P+ L FPN M LW D E PR + Sbjct: 413 DPGYRWSETVPTPNQP---ALHGFPNAPMRATHLWAAPDRVTEAAPRPR----------- 458 Query: 483 XXXXXXXXXXXXRLLVEEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXXXXXXX 542 + VE+W R T P D Sbjct: 459 -----------LTVAVEDW-----RHTTSPTTPTAADLGFAGAHPLTRRLADAAAAQGGC 502 Query: 543 RVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTD----- 597 RVV + L I+ PE +LD AA ++G D G+ D Sbjct: 503 RVV------APGEAEILAIVAPELDQLDAVAAVEQIGA---------REDAGLPDYRGLI 547 Query: 598 ------CWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQD 651 WL+TV E D AA +A RSIG E P F HLDLP Sbjct: 548 GPRCRAVWLLTVRAEHVDGDDDQACVAQAALAAMHRSIGFEFPDQAFGHLDLPHRDVDAA 607 Query: 652 WAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCP----EHVLIIGGTGNL 707 AH I+ L A E+A R + + EHV+I GG+G + Sbjct: 608 TAHAIIEVL-LAEPAEVALRGEQSPRRHVRTFRAHNESADRPLDDAALEHVVITGGSGAI 666 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 GL + + RG R +TL+SR+G AAV L +L + A+++ RCD+ D AAV++ A Sbjct: 667 GLHYARYCLQRGTRNLTLLSRNGIEAAV---LRELTGSHDARVSAPRCDITDRAAVTQAA 723 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ + A L+IH A + +D+T D AKV G+ + D +P CRI+ C Sbjct: 724 ARYAGSGATLLIHTAGIAQARSRTDLTGADVAAVCAAKVRGLALMADVWPLRPDCRILAC 783 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAA 887 SS GG YAA+NRMLD +A +LRA GLDC +++WG W + S +A+ Sbjct: 784 SSVFGVWGGYHHAAYAASNRMLDVLATQLRARGLDCTAIRWGLWQDAGVVAGSEIARTER 843 Query: 888 IGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPA 947 G++ M P A+ + R + ++ DF+R + E+ G S+ +P + A A Sbjct: 844 SGLVAMDPRRALQASLHRYESDPLIFDADFERLQVFFESQGMPMPFSD--TPTRDDEAAA 901 Query: 948 EPADLP--GRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEV 1005 PA P + D S ++ LG+DSL AL+LR+R++ + + V Sbjct: 902 APAGKPLAELVRAELAATLHLGDSVSIDPSASLIDLGVDSLLALDLRKRLRRTVGNSVPV 961 Query: 1006 SDLLGGASIADVLAQL 1021 + +LGG ++A+++ L Sbjct: 962 ARMLGGITVAELVDAL 977 >tr|Q7TYQ6|Q7TYQ6_MYCBO Tax_Id=1765 (mbtD)SubName: Full=POLYKETIDE SYNTHETASE MBTD (POLYKETIDE SYNTHASE);[Mycobacterium bovis] Length = 1004 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 2 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 62 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 120 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 121 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 181 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 241 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 298 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 299 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 355 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 356 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 414 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 415 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 460 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 461 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 499 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 500 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 559 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 560 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 619 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 620 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 678 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 679 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 735 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 736 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 795 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 796 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 855 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 856 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 904 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 905 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 964 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 965 GATVSLATLMGDITGDGLVAKL 986 >tr|P71719|P71719_MYCTU Tax_Id=1773 (mbtD)SubName: Full=POLYKETIDE SYNTHETASE MBTD (POLYKETIDE SYNTHASE);[Mycobacterium tuberculosis] Length = 1004 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 2 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 62 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 120 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 121 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 181 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 241 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 298 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 299 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 355 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 356 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 414 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 415 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 460 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 461 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 499 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 500 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 559 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 560 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 619 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 620 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 678 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 679 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 735 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 736 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 795 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 796 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 855 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 856 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 904 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 905 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 964 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 965 GATVSLATLMGDITGDGLVAKL 986 >tr|C6DNA3|C6DNA3_MYCTK Tax_Id=478434 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis] Length = 1004 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 2 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 62 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 120 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 121 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 181 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 241 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 298 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 299 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 355 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 356 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 414 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 415 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 460 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 461 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 499 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 500 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 559 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 560 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 619 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 620 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 678 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 679 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 735 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 736 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 795 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 796 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 855 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 856 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 904 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 905 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 964 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 965 GATVSLATLMGDITGDGLVAKL 986 >tr|C1AQU4|C1AQU4_MYCBT Tax_Id=561275 (mbtD)SubName: Full=Polyketide synthetase;[Mycobacterium bovis] Length = 1004 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 2 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 62 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 120 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 121 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 181 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 241 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 298 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 299 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 355 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 356 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 414 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 415 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 460 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 461 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 499 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 500 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 559 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 560 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 619 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 620 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 678 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 679 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 735 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 736 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 795 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 796 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 855 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 856 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 904 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 905 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 964 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 965 GATVSLATLMGDITGDGLVAKL 986 >tr|A5U574|A5U574_MYCTA Tax_Id=419947 (mbtD)SubName: Full=Putative polyketide synthase MbtD;[Mycobacterium tuberculosis] Length = 1004 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 2 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 62 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 120 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 121 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 181 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 241 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 298 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 299 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 355 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 356 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 414 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 415 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 460 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 461 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 499 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 500 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 559 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 560 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 619 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 620 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 678 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 679 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 735 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 736 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 795 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 796 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 855 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 856 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 904 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 905 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 964 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 965 GATVSLATLMGDITGDGLVAKL 986 >tr|A1KL71|A1KL71_MYCBP Tax_Id=410289 (mbtD)SubName: Full=Polyketide synthetase mbtD;[Mycobacterium bovis] Length = 1004 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 2 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 62 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 120 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 121 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 181 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 241 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 298 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 299 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 355 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 356 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 414 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 415 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 460 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 461 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 499 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 500 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 559 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 560 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 619 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 620 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 678 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 679 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 735 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 736 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 795 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 796 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 855 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 856 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 904 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 905 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 964 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 965 GATVSLATLMGDITGDGLVAKL 986 >tr|Q7D790|Q7D790_MYCTU Tax_Id=1773 SubName: Full=Polyketide synthase, putative;[Mycobacterium tuberculosis] Length = 1009 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 7 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 66 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 67 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 125 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 126 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 185 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 186 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 245 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 246 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 303 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 304 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 360 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 361 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 419 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 420 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 465 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 466 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 504 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 505 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 564 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 565 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 624 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 625 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 683 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 684 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 740 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 741 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 800 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 801 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 860 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 861 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 909 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 910 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 969 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 970 GATVSLATLMGDITGDGLVAKL 991 >tr|A5WPZ6|A5WPZ6_MYCTF Tax_Id=336982 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis] Length = 1004 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 2 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 62 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 120 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 121 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 181 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 241 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 298 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 299 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 355 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 356 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 414 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 415 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 460 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 461 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 499 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 500 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 559 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 560 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 619 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 620 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 678 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 679 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 735 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 736 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 795 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 796 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 855 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 856 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 904 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 905 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 964 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 965 GATVSLATLMGDITGDGLVAKL 986 >tr|A4KJD1|A4KJD1_MYCTU Tax_Id=395095 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis str. Haarlem] Length = 1004 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 2 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 61 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 62 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 120 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 121 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 180 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 181 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 240 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 241 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 298 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 299 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 355 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 356 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 414 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 415 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 460 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 461 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 499 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 500 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 559 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 560 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 619 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 620 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 678 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 679 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 735 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 736 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 795 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 796 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 855 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 856 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 904 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 905 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 964 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 965 GATVSLATLMGDITGDGLVAKL 986 >tr|A2VKA7|A2VKA7_MYCTU Tax_Id=348776 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis C] Length = 1009 Score = 397 bits (1019), Expect = e-108 Identities = 304/1042 (29%), Positives = 464/1042 (44%), Gaps = 81/1042 (7%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 A +LPDG + VLLSA EL+ +A A+ D++ P T ++ L Sbjct: 7 APKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRAV 66 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL + L+A+ EHP + R+ + R+ +VF + Y +P Sbjct: 67 LRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQ-AFVFPGQGGHWPGMGAVAYRELP 125 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI---VQPALFTQMAALAAMWRSF 180 +R D CA AF A SP YL+ D+ A ++ A F ALA +WRS Sbjct: 126 TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC 185 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GEVAAAY++G+ITL DAV V+ R +++ Sbjct: 186 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS 245 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 L+A GW +LSVVN+ V +SGER+ V IVDT+ G FAR I V +P HTS++ Sbjct: 246 A-LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVL- 303 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 + LR + +QL F++ + +G T G + GDYW+ NLR+ VRFD+A+ Sbjct: 304 ---ESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 360 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 +A++ F+E++ HP L AI +N + D PA++VG++ R + + N+ Sbjct: 361 SAIRCGARAFIEISAHPALLFAIGQNCEGAAN-LPDGPAVLVGSARRGERFVDALSANIV 419 Query: 421 QLAVHDLNYPWECLRAEP-DGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXX 479 AV D YPW L +P DG + L FPN M + +W + E LP Sbjct: 420 SAAVADPGYPWGDLGGDPLDG--DVDLSGFPNAPMRAVPMW-AHPEPLP----------- 465 Query: 480 XXXXXXXXXXXXXXXRLLVEEWVRL--SQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXX 537 + VE W R+ S R + ++D Sbjct: 466 ----------PVSGLTIAVERWERMVPSTPVAGRHRHLAVLD-----------LGAHRAL 504 Query: 538 XXXXXRVVNGEND---GTGADVNTLVILLPETPKLDG-RAAAAEVGGFFSNRAWWP-GVD 592 ++ D D ++++ P+ D RAA A + +P + Sbjct: 505 AQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIG 564 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDW 652 LVTVG E AAD P AA +A RSIG EHP F HLDLP+ Sbjct: 565 ARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVL 624 Query: 653 AHPIVAALHTANEPELAYRDGA-----FYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNL 707 ++ A+ E A R F + V++ GG G + Sbjct: 625 GVSVITAV-LRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAI 683 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLA 767 G+ + + A GARRI L+SR AA +A LR I CD+ DP +S +A Sbjct: 684 GMHYARYLAEHGARRIVLLSR---RAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIA 740 Query: 768 AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 A++ A LI+HAA + S +T+ + AKV+G+ Q+++ +P R +LC Sbjct: 741 AEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLC 800 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW-------TVHFDLDAS 880 SS GG G V Y+AANR+LD MA +LRA+G CV+V+WG W DA Sbjct: 801 SSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAV 860 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPV 940 ++A++ G+ M P +AI + + +V A D R + +L++ + Sbjct: 861 TIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQF----------- 909 Query: 941 SETAAPAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEF 999 P +P + + + + LG+DS+ AL+LR R+K Sbjct: 910 ERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSI 969 Query: 1000 DHELEVSDLLGGASIADVLAQL 1021 + ++ L+G + ++A+L Sbjct: 970 GATVSLATLMGDITGDGLVAKL 991 >tr|A4T2C9|A4T2C9_MYCGI Tax_Id=350054 SubName: Full=Acyl transferase region;[Mycobacterium gilvum] Length = 960 Score = 396 bits (1018), Expect = e-108 Identities = 325/1030 (31%), Positives = 468/1030 (45%), Gaps = 98/1030 (9%) Query: 8 LPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXX 67 LPDG IPVLLSA EL+ +A L + + P++ ++A L Sbjct: 2 LPDGRIPVLLSAHAEELIGEDARRLLGFLDSAPEVDA--VAATLLRVRRRNRHRAVVRAA 59 Query: 68 TRAELIDALQAMIDRYEHPALIRT-DPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFR 126 R+EL DAL A+ EHP + R+ +P A RR +V+ Y ++ +R Sbjct: 60 DRSELADALSALAAGQEHPLVSRSAEPDAHRR--AFVYPGQGNQWPAMGAEAYRTLRDYR 117 Query: 127 AEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNV 186 D CA AF A SP YL D GS Q A FT AL A+WR+ G+AP++ Sbjct: 118 QAADVCAAAFTAAGAPSPLRYLTDAAAVT-GSQVEAQAAQFTHAVALTAVWRAHGVAPDM 176 Query: 187 TIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLAR 246 T+GHS GEVAAA+V+G ITL +A V+ I E + L+ Sbjct: 177 TVGHSLGEVAAAHVAGAITLAEAAAVV-IARATVLEGLADGYRMAVLGLTPEDAQSLIES 235 Query: 247 CSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKL 306 GW +L+VVN+ VG+SGER+ V ++ + G FAR + + +PAHTSL+ D L Sbjct: 236 VPGWLELAVVNAASSVGVSGERDAVDALLAQASSRGVFARSVTMAFPAHTSLL----DGL 291 Query: 307 RAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRD 366 RA L F T I LG+ G + E DYWF NLRN VRFD+A AAAV+ Sbjct: 292 RADFVRLLAPARFQQTAIPFLGSATGEAVPPETDFADYWFANLRNTVRFDRAAAAAVRAG 351 Query: 367 VETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHD 426 FVE++ HP L L +L A D A+ VG+ R A + + +A +A HD Sbjct: 352 ANLFVEMSAHPAL-------LFSLGQSAGD--ALTVGSGRRDAPLVETLSAGIATVAAHD 402 Query: 427 LNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLW-LPYDEVLPRRQXXXXXXXXXXXXXX 485 +PW + A L FPN M + LW LP P Sbjct: 403 AEFPWHDVIDTTRPA----LRGFPNAPMRSVHLWALPQPLPAP----------------- 441 Query: 486 XXXXXXXXXRLLVEEWV--RLSQRSLTPPR--VVGIVDPTGXXXXXXXXXXXXXXXXXXX 541 L E W R ++R L R V+ + P G Sbjct: 442 ------PSLTLATEAWEPHRPAERGLALRRTAVLDLAGPRGGLGDLLRDAVDHHP----- 490 Query: 542 XRVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSN--RAWWPGVDTGVTDCW 599 G D + ++ + P D R + A + + + V T D W Sbjct: 491 -----GMVSTPVHDADLVLAVAPNLGDPDVRESVAALTALIDDGLLRYPDDVGTDCRDLW 545 Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAA 659 LVT E T D P P AA +A RSIG E+P FRHLDLP + A + A Sbjct: 546 LVTTAAEQLT-GDPTPRPAQAALAAMHRSIGFEYPDRAFRHLDLPPVVLDEAAASAALDA 604 Query: 660 LHTANEPELAYRD----GAFYAK--RIXXXXXXXXXXXXXCPEHVLIIGGTGNLGLEFCD 713 + + +LA RD A +A+ +HV+I GG+G +G + Sbjct: 605 VLGGGD-DLALRDIDGMPAVFARTEHETVTTPESWADDPGALDHVVITGGSGTVGQHYAR 663 Query: 714 HFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRST 773 H A RGARRITL+SR G A+ +A + CDV DP A++ AA+ Sbjct: 664 HLAERGARRITLLSRHG---------AKGSAAGGPGVQTVCCDVTDPVALAVAAAEFGGD 714 Query: 774 PADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARAT 833 A L+IHAA E ++ + AKV G+ ++ +A+PR G R+++CSS Sbjct: 715 GATLVIHAAGTAQFAEHDTLSAAAFADTAAAKVEGLFRIAEAWPRRPGARMLVCSSVSGL 774 Query: 834 IGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPM 893 GGRG YAAANR++D A ++RAEG+ C +V++G + +D S+ + G++P+ Sbjct: 775 WGGRGHAAYAAANRLVDVTAAQMRAEGIRCAAVRFGLFGTGI-VDEESVNLIGRSGLVPL 833 Query: 894 PPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVS--ETAAPAEPAD 951 P +A+A ++ L + IV + DRAR L+ F P SP S +T A A+ Sbjct: 834 DPDDAVAASLRDLPGDPIV--YSADRAR--LQIFRDDPAPPTATSPASGGDTTA-VVLAE 888 Query: 952 LPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGG 1011 L L D ++ +G+DSL AL+LR+R++ + ++ +LGG Sbjct: 889 LTSVLG---------IEPAGVDLDASLLDMGVDSLLALDLRKRLRRATGRSVPLAAMLGG 939 Query: 1012 ASIADVLAQL 1021 + A+++ L Sbjct: 940 MTGAELITGL 949 >tr|A0QE93|A0QE93_MYCA1 Tax_Id=243243 SubName: Full=MbtD protein;[Mycobacterium avium] Length = 1013 Score = 396 bits (1017), Expect = e-108 Identities = 315/1037 (30%), Positives = 455/1037 (43%), Gaps = 89/1037 (8%) Query: 8 LPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTP--GPISAMLFXXXXXXXXXXXXX 65 LPDG IPVLLS+ PEL+ +A A+ +++ + T G ++A L Sbjct: 7 LPDGRIPVLLSSHDPELIRRDAAAILEYLDRIGESTEATGAVAATLLRLRRVRRHRALLR 66 Query: 66 XXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAF 125 RAEL L A+ EH ALI RI +VF Y +PA+ Sbjct: 67 AADRAELAAGLAAIARGEEH-ALITRSARTTPPRIAFVFPGQGNQWQAMGADAYRRLPAY 125 Query: 126 RAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPN 185 R DRCAQAF A SP YL+ + Q + +Q A FT ALA WR FG+ P Sbjct: 126 REAADRCAQAFVAAGFPSPLPYLVSPDEQS-WTRPEIQGAQFTHAVALAEAWRCFGVLPE 184 Query: 186 VTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLA 245 + IGHS GEVAAAYV+ I+L DAV ++ R + E LLA Sbjct: 185 MAIGHSLGEVAAAYVAEAISLPDAVALVVARATVVDRLTGRYAMAVLGAGAAD-AESLLA 243 Query: 246 RCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADK 305 GW ++S VN P ++G+ + V V + FA + V YP HTS + Sbjct: 244 TTPGWVEVSAVNGPASTVVAGDHDAVAAAVRLAQQREIFAHQLFVDYPGHTSALR----P 299 Query: 306 LRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQR 365 LRAA+ + +F D+ I +G+T GA + + YW+ NL + VRFD A+ A Sbjct: 300 LRAALAELTPQSAFRDSPIRFIGSTRGAEVAATTDYASYWYENLCSTVRFDLAVQCARSC 359 Query: 366 DVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVH 425 + FVEL+ HP+L L L DD A++VG+ R + ++A +A Sbjct: 360 GADAFVELSAHPSL-------LYPLSGIIDDESAVIVGSGHRDRPITESLSASMAAVATA 412 Query: 426 DLNYPWECLRAEPDGAQALPLL-DFPNTRMNEIRLWLPYD---EVLPRRQXXXXXXXXXX 481 D Y W +E + P L FPN M LW D E PR + Sbjct: 413 DPGYRW----SETVPTRNQPALHGFPNAPMRATHLWAAPDRVTEAAPRPR---------- 458 Query: 482 XXXXXXXXXXXXXRLLVEEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXXXXXX 541 + VE+W R T P D Sbjct: 459 ------------LTVAVEDW-----RHTTSPTTPTAADLGFAGAHPMTRRLADAAAAQGG 501 Query: 542 XRVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTD---- 597 RVV + + I+ PE +LD AA ++G D G+ D Sbjct: 502 CRVV------APGEAEIVAIVAPELDQLDAVAAVEQIGA---------REDAGLPDYRGL 546 Query: 598 -------CWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQ 650 WL+TV E D AA +A RSIG E P F H+DLP Sbjct: 547 IGPRCRAVWLLTVRAEHVDGDDDQACVAQAALAAMHRSIGFEFPDQAFGHVDLPHRDVDA 606 Query: 651 DWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCP----EHVLIIGGTGN 706 A+ I+ L A E+A R + + EHV+I GG+G Sbjct: 607 ATAYAIIEVL-LAEPAEVALRGEQSPRRHVRTFRAHHESADRPLDDAALEHVVITGGSGA 665 Query: 707 LGLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRL 766 +GL + + RGAR +TL+SR+G AAV L +L + A+++ RCD+ D AAV+ Sbjct: 666 IGLHYARYCLQRGARNLTLLSRNGIEAAV---LRELTGSHDARVSAPRCDITDRAAVTEA 722 Query: 767 AAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVL 826 AA++ + A L+IH A + +D+T D AKV G+ + D +P CRI+ Sbjct: 723 AARYAGSGATLLIHTAGIAQARSRTDLTGADVAAVCAAKVRGLALMADVWPLRPDCRILA 782 Query: 827 CSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLA 886 CSS GG YAA+NRMLD +A +LRA GLDC +++WG W + S +A+ Sbjct: 783 CSSVFGVWGGYHHAAYAASNRMLDVLATQLRARGLDCTAIRWGLWQDAGVVAGSEIARTE 842 Query: 887 AIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAP 946 G++ M P A+ + R + ++ DF+R + E+ G S+ +P + A Sbjct: 843 RSGLVAMDPRRALQASLHRYESDPLIFDADFERLQVFFESQGMPMPFSD--TPTRDDEAA 900 Query: 947 AEPADLP--GRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELE 1004 A PA P + D S ++ LG+DSL AL+LR+R++ + + Sbjct: 901 AAPAGKPLAEVVRAELAATLHLGDSVSIDPSASLIDLGVDSLLALDLRKRLRRTVGNSVP 960 Query: 1005 VSDLLGGASIADVLAQL 1021 V+ +LGG ++A+++ L Sbjct: 961 VARMLGGITVAELVDAL 977 >tr|A0R0U6|A0R0U6_MYCS2 Tax_Id=246196 SubName: Full=Polyketide synthetase mbtd;[Mycobacterium smegmatis] Length = 997 Score = 378 bits (971), Expect = e-102 Identities = 310/1034 (29%), Positives = 448/1034 (43%), Gaps = 74/1034 (7%) Query: 8 LPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXX 67 L D +PV+LSA +L+ +ATA+ ++ D P ++ L Sbjct: 7 LCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYTLLRTRRLRRHRAVIRAG 66 Query: 68 TRAELIDALQAMIDRYEHPALIRT---DPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPA 124 EL L+A+ D +HP + R P + RRR+ +VF Y + Sbjct: 67 GLDELTAGLRALADGDDHPLVTRAAAPQPGS-RRRVAFVFPGQGSQWPSMGVEAYR-LDD 124 Query: 125 FRAEVDRCAQAFEAQSCGSPRNYLL---DKNFQ-DDGSAGIVQPALFTQMAALAAMWRSF 180 +RAEVDRCA AFEA SP +YLL D +D S +Q A F ALA +WRS Sbjct: 125 YRAEVDRCAAAFEAAGAASPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSH 184 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P++T+GHS GE+ AAYV+G ITL +AV ++ R + Sbjct: 185 GVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAA 244 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 E ++A GW +LSVVNSP V +SGE V V T+ G FA+ I + +PAHT+ + Sbjct: 245 E-VIAETPGWLELSVVNSPSSVAVSGETGAVAAAVRTVAARGAFAKEIEMWFPAHTTAL- 302 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 D +RA + L F +T + +G+ +T+ DYW+ NLR VRFD+A+A Sbjct: 303 ---DGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQAVA 359 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 A +R FVEL+ HP L + E L + R ++VG+ R N+ Sbjct: 360 RAARRGARIFVELSAHPALLFNMGELLESTRG------VVLVGSGRRDEPLPERLADNVI 413 Query: 421 QLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQXXXXXXXXX 480 +A+ D Y W R + A+ L DFP M LW D + P Sbjct: 414 TVALADAGYRW---RDQLGDCHAV-LPDFPFAPMRAEHLWAQPDPLPP------------ 457 Query: 481 XXXXXXXXXXXXXXRLLVEEWVRLSQRSLTPPRVVGIVDPTGXXXXXXXXXXXXXXXXXX 540 + E+W +++ ++ + +V Sbjct: 458 ----------VTGLTVAAEQWHQVAVPEVSGHHRIAVV--------GLDSECAVAGHLRD 499 Query: 541 XXRVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAW-WPGVDTGVT-DC 598 + G A +TL+++ P + D A E+G +P + T T D Sbjct: 500 AAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRDV 559 Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVA 658 WLVT GE PV AA +A RSI EHP FR LD+P G + A VA Sbjct: 560 WLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDVPMGLDTEA-AVTAVA 618 Query: 659 ALHTANEPELAYR----DG---AFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNLGLEF 711 A+ T +LA R DG + + + + V+I GGTG +GL+F Sbjct: 619 AMVTGT-TDLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGVLDDVVITGGTGAVGLQF 677 Query: 712 CDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHR 771 A GARRI L+SR+G + L +I RCD+ D V +AA+ Sbjct: 678 ARRLAALGARRIVLLSRNGIEGNRVDEL-----PLGVEIVAPRCDLTDIPRVRDVAAEFG 732 Query: 772 STPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSAR 831 A LI+HAA S +T A AK+ GI VL A+P RI+LCSS Sbjct: 733 GQGASLIVHAAATATIAAGSALTGAAAQATFTAKLAGIENVLAAWPVRPDARILLCSSVS 792 Query: 832 ATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVI 891 GG G YAAANR+LD MA RLR+EG C +V+WG W +DA + ++ G+ Sbjct: 793 GLWGGHGHAAYAAANRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLR 852 Query: 892 PMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSE----TAAPA 947 M P A+ +Q + +V + D R L T E A A Sbjct: 853 AMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGREATHAAQHRDAGPPADA 912 Query: 948 EPADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSD 1007 E D + D ++ LG+DSL AL+LR+++K + ++ Sbjct: 913 EHHDTGAAVRIALAAVLKLADTTGLDLDASLLDLGVDSLLALDLRKKLKKTTGRSVPLAT 972 Query: 1008 LLGGASIADVLAQL 1021 LLGG + +++ L Sbjct: 973 LLGGVTATELIEHL 986 >tr|D0L275|D0L275_GORB4 Tax_Id=526226 SubName: Full=Acyl transferase;[Gordonia bronchialis] Length = 467 Score = 257 bits (657), Expect = 5e-66 Identities = 172/465 (36%), Positives = 234/465 (50%), Gaps = 25/465 (5%) Query: 8 LPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXX 67 LPDGT+ + +S++ P L EATA+ ++ HPD P +S ML Sbjct: 6 LPDGTVALPISSEHPAGLADEATAVAGYLETHPDADPAAVSRMLLRTRSLRRHRVIVRAH 65 Query: 68 ---TRAEL-IDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 TR + I AL+A HP +IR PA R + VF F+ Sbjct: 66 GDRTRNDATIAALRAAAAGSAHPDVIRPGPAR-RLAVAMVFPGQGSQTAGMGIEFHRHCA 124 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIA 183 ++R V+ F SP +YLLD + +D + VQPA+F LA MWR G+ Sbjct: 125 SYRRHVEDVNSEFGRVVGISPLDYLLDDDHPEDVRS--VQPAIFLHTLGLARMWRDAGLR 182 Query: 184 PNVTIGHSQGEVAAAYVSGTITLEDAV-----RVIGIRXXXXXXXXXXXXXXXXXXXDRE 238 P TIGHSQGE AAA SG ++L D + R +GI R+ Sbjct: 183 PAATIGHSQGEFAAAVESGHLSLRDGIMLVTDRAVGIEKVETSGRHEPSAMAVIGAT-RD 241 Query: 239 TCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSL 298 ED LAR +GW +L+VVNS + ISGER V +V T G FAR IRV + H+SL Sbjct: 242 AVEDRLARQTGWVELAVVNSTTIQAISGERTAVDDVVADFTAAGVFARRIRVDHAGHSSL 301 Query: 299 IHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKA 358 + AD+ + L F D +I C+G TLG PIT +LP+ YW+WNLRN VRFD A Sbjct: 302 LRHYADEFTLSAA-HLDATEFHDGEIPCIGGTLGEPITRDLPLAAYWYWNLRNTVRFDLA 360 Query: 359 IAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRN 418 IA AV+ + FVE++EHPT+ L+I E +A AD A++VGT ++ L EFT N Sbjct: 361 IATAVRSGITGFVEMSEHPTMLLSIGETVA--EQGAD---AVIVGTGKKRTDPLAEFTAN 415 Query: 419 LAQLAVHDLNYPWECLRAEPDG-AQALPLLDFPNTRMNEIRLWLP 462 + D ++ W+ DG +PL DFP++R + W P Sbjct: 416 ALSVFGADSDFHWDA-----DGLVDQIPLPDFPHSRFDATVYWAP 455 >tr|A3Q279|A3Q279_MYCSJ Tax_Id=164757 SubName: Full=Acyl transferase domain protein;[Mycobacterium sp.] Length = 978 Score = 241 bits (616), Expect = 3e-61 Identities = 159/478 (33%), Positives = 224/478 (46%), Gaps = 30/478 (6%) Query: 7 RLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXX 66 R PDG IPVLLSA +L+ +A A+ ++ P + ++ L Sbjct: 6 RWPDGRIPVLLSAHAGDLVAEDARAVLGYLDHDPAASVADVAGHLLTTRRVRRHRTVVRA 65 Query: 67 XTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFR 126 R EL D L+A+ + EHP L+ RI +VF YE +P +R Sbjct: 66 GDRDELADGLRAVAEGAEHP-LVACSAEGSPSRIAFVFPGQGTQWPSMGTQAYEELPQYR 124 Query: 127 AEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNV 186 A D CA+AF A SP YL ++ S ++ A FT ALA +WRS+G+ P++ Sbjct: 125 AAADACAEAFTAAGAASPMRYLTTPGTAEEFSEAEIEGAQFTHAVALAHVWRSYGVLPDI 184 Query: 187 TIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLAR 246 T+GHS GE+ AAY++G ITL DAV V+ I D ET + ++A Sbjct: 185 TVGHSLGEIGAAYLAGAITLADAVAVV-IARAEVVDRLSGDHAVAVLGVDPETAQQVIAA 243 Query: 247 CSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKL 306 GW +LSVVN+ V +SG+R V V + E G FAR I V +P HTS++ + L Sbjct: 244 TPGWLELSVVNAATSVAVSGDRRAVSAAVALVREQGRFAREITVGFPVHTSIL----EPL 299 Query: 307 RAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRD 366 R QL F DT + +G G + + GDYW+ NLR +VRFD A +A + Sbjct: 300 RDDFVKQLPQAVFADTPVQFIGGATGDVVPAGAMFGDYWYANLRTMVRFDHAFESARRCG 359 Query: 367 VETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHD 426 TFVEL+ HP L L A+ D D A +VG+ R + NLA A+ D Sbjct: 360 ATTFVELSAHPQL-------LFAMGDLLGDTTATLVGSGRRDTPITEALSDNLAVAAISD 412 Query: 427 LNYPWE----------------CLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLP 468 + W +RA P AQ PL + + + + +W P D+V P Sbjct: 413 PGHGWRDAVEPTAHRLRGFPNAPMRATPLWAQPEPLSETADITVAQ-EVWQPIDDVTP 469 Score = 200 bits (509), Expect = 7e-49 Identities = 160/489 (32%), Positives = 223/489 (45%), Gaps = 37/489 (7%) Query: 551 GTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTG--VTDCWLVTVGGEAA 608 GT + +V++ P+ D + A V + A G D WLVT G E Sbjct: 506 GTPDTADVMVVVAPQPGGADAKTAVTTVTDLVGSGALRYPASAGPRCRDIWLVTAGAERV 565 Query: 609 TAADGPPDPVHAAASAGF-RSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAALHT-ANEP 666 G P + AAA A RS+G E+P +GF HLDLPA T +V L T A E Sbjct: 566 RT--GEPQALSAAAIAAMHRSLGLENPELGFHHLDLPADPTIDT---AVVDTLLTGAGER 620 Query: 667 ELAYRDGAFYAKRIXXXXXXXXXXXXXCP--EHVLIIGGTGNLGLEFCDHFAHRGARRIT 724 + DG +R + V+I GG G +GL + H A RGARRI Sbjct: 621 AIRGGDGPVLYRRTVADAPVAPAWSLDSGILDEVVITGGAGRIGLHYARHLAERGARRIV 680 Query: 725 LVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIHAAVA 784 L+SR AV LA+L +A ++ CD+ D ++ R A A L+IHAA A Sbjct: 681 LLSRRAVDPAV---LAELTAARGTEVVSVPCDLTDRESI-RTATDFAGIGASLVIHAAGA 736 Query: 785 YASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQVMYAA 844 + A N L AKV G+ + D +P RIVLCSS GG G +Y+A Sbjct: 737 ATFASGDRLDAAAAVNTLGAKVTGLAHLADLWPLHPDARIVLCSSVSGLWGGHGHAVYSA 796 Query: 845 ANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFD---LDASSMAQLAAIGVIPMPPAEAIAL 901 ANRMLDAMA RLRA+G CVSV+WG W + A+ A++ G+ PM P AI Sbjct: 797 ANRMLDAMAGRLRADGHRCVSVRWGLWRSDSGEGIVGAAETARIERSGLRPMAPLPAIEA 856 Query: 902 GMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSE------TAAPAEPADLPGR 955 + + +V + D R + + S PV + TAAP + AD Sbjct: 857 SLCDHTVDPLVFSADPHRMQ----------MFSAATEPVRDPQTAETTAAPVDTAD---A 903 Query: 956 LSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIA 1015 + D + LG+DSL AL+LR+R + + ++ LLGG + A Sbjct: 904 VRAELAAVLKITDPGGIDLDASLFDLGVDSLLALDLRKRFRRVLGRTVPLATLLGGVTGA 963 Query: 1016 DVLAQLGSR 1024 +++A+L + Sbjct: 964 ELVAELDEK 972 >tr|Q1B6B0|Q1B6B0_MYCSS Tax_Id=164756 SubName: Full=Acyl transferase region;[Mycobacterium sp.] Length = 978 Score = 240 bits (612), Expect = 8e-61 Identities = 159/478 (33%), Positives = 225/478 (47%), Gaps = 30/478 (6%) Query: 7 RLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXX 66 R PDG IPVLLSA +L+ +A A+ ++ P + ++ L Sbjct: 6 RWPDGRIPVLLSAHAGDLVAEDARAVLGYLDHDPAASVADVAGHLLTTRRVRRHRTVVRA 65 Query: 67 XTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFR 126 R EL D L+A+ EHP + R+ + RI +VF YE +P +R Sbjct: 66 GDRDELADGLRAVAHGAEHPLVARSAEGS-PSRIAFVFPGQGTQWPSMGTQAYEELPQYR 124 Query: 127 AEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNV 186 A D CA+AF A SP YL + S ++ A FT ALA +WRS+G+ P++ Sbjct: 125 AAADACAEAFTAAGAASPMRYLTTPGTAEGFSEAEIEGAQFTHAVALAHVWRSYGVLPDI 184 Query: 187 TIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLAR 246 T+GHS GE+ AAY++G ITL DAV V+ I D ET + ++A Sbjct: 185 TVGHSLGEIGAAYLAGAITLADAVAVV-IARAEVVDRLSGDHAVAVLGVDPETAQQVIAA 243 Query: 247 CSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKL 306 GW +LSVVN+ V +SG+R V V + E G FAR I V +P HTS++ + L Sbjct: 244 TPGWLELSVVNAATSVAVSGDRRAVSAAVARVREQGRFAREITVGFPVHTSIL----EPL 299 Query: 307 RAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRD 366 R QL F D+ + +G G + + GDYW+ NLR +VRFD+A +A + Sbjct: 300 RDDFVKQLPQAVFADSPVQFIGGATGDVVPAGAMFGDYWYANLRTMVRFDRAFESARRCG 359 Query: 367 VETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHD 426 TFVEL+ HP L L A+ D D A +VG+ R + NLA AV D Sbjct: 360 ATTFVELSAHPQL-------LFAMGDLLGDTTATLVGSGRRDTPITEALSDNLAVAAVSD 412 Query: 427 LNYPWE----------------CLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLP 468 + W +RA P AQ PL + + + + +W P D+V P Sbjct: 413 PGHGWRDAVERTAHRLRGFPNAPMRATPLWAQPEPLSETADITVAQ-EVWQPIDDVTP 469 Score = 199 bits (506), Expect = 2e-48 Identities = 161/490 (32%), Positives = 224/490 (45%), Gaps = 39/490 (7%) Query: 551 GTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTG--VTDCWLVTVGGEAA 608 GT + +V++ P+ D + A V + A G D WLVT G E Sbjct: 506 GTPDTADVMVVVAPQPGGADAKTAVTTVTDLVGSGALRYPASAGPRCRDIWLVTAGAERV 565 Query: 609 TAADGPPDPVHAAASAGF-RSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAALHTANEPE 667 A G P + AAA A RS+G E+P +GF HLDLPA T +V L T E Sbjct: 566 RA--GEPQALSAAAIAAMHRSLGLENPELGFHHLDLPADPTIDT---AVVDTLLTG-AGE 619 Query: 668 LAYRDG---AFYAKRIXXXXXXXXXXXXX-CPEHVLIIGGTGNLGLEFCDHFAHRGARRI 723 LA R G Y + + + V+I GG G +GL + H A RGARRI Sbjct: 620 LAIRGGDGPVLYRRTVADAPVAPAWSLGSGILDEVVITGGAGRIGLHYARHLAERGARRI 679 Query: 724 TLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIHAAV 783 L+SR AV LA+L + ++ CD+ D ++ R A A L+IHAA Sbjct: 680 VLLSRRAVDPAV---LAELTAPRGTEVVSVPCDLTDRESI-RTATDFAGIGASLVIHAAG 735 Query: 784 AYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQVMYA 843 A E + A N L AKV G+ + D +P RIVLCSS GG G +Y+ Sbjct: 736 AATFAEGDRLDAAAAVNTLGAKVTGLAHLADLWPLHPDARIVLCSSVSGLWGGHGHAVYS 795 Query: 844 AANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFD---LDASSMAQLAAIGVIPMPPAEAIA 900 AANRMLDAMA RLRA+G CVSV+WG W + A+ A++ G+ PM P AI Sbjct: 796 AANRMLDAMAGRLRADGHRCVSVRWGLWRSDSGEGIVGAAETARIERSGLRPMAPLPAIE 855 Query: 901 LGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSE------TAAPAEPADLPG 954 + + +V + D R + + S PV + TAAP + AD Sbjct: 856 ASLCDHTVDPLVFSADPHRMQ----------MFSAATEPVRDPQTAETTAAPVDTAD--- 902 Query: 955 RLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASI 1014 + D + LG+DSL AL+L +R + + ++ LLGG + Sbjct: 903 AVRAELAAVLKITDPGGIDLDASLFDLGVDSLLALDLGKRFRRVLGRTVPLATLLGGVTG 962 Query: 1015 ADVLAQLGSR 1024 A+++A+L + Sbjct: 963 AELVAELDEK 972 >tr|A1UIR6|A1UIR6_MYCSK Tax_Id=189918 SubName: Full=Acyl transferase domain protein;[Mycobacterium sp.] Length = 978 Score = 240 bits (612), Expect = 8e-61 Identities = 159/478 (33%), Positives = 225/478 (47%), Gaps = 30/478 (6%) Query: 7 RLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXX 66 R PDG IPVLLSA +L+ +A A+ ++ P + ++ L Sbjct: 6 RWPDGRIPVLLSAHAGDLVAEDARAVLGYLDHDPAASVADVAGHLLTTRRVRRHRTVVRA 65 Query: 67 XTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFR 126 R EL D L+A+ EHP + R+ + RI +VF YE +P +R Sbjct: 66 GDRDELADGLRAVAHGAEHPLVARSAEGS-PSRIAFVFPGQGTQWPSMGTQAYEELPQYR 124 Query: 127 AEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNV 186 A D CA+AF A SP YL + S ++ A FT ALA +WRS+G+ P++ Sbjct: 125 AAADACAEAFTAAGAASPMRYLTTPGTAEGFSEAEIEGAQFTHAVALAHVWRSYGVLPDI 184 Query: 187 TIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLAR 246 T+GHS GE+ AAY++G ITL DAV V+ I D ET + ++A Sbjct: 185 TVGHSLGEIGAAYLAGAITLADAVAVV-IARAEVVDRLSGDHAVAVLGVDPETAQQVIAA 243 Query: 247 CSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKL 306 GW +LSVVN+ V +SG+R V V + E G FAR I V +P HTS++ + L Sbjct: 244 TPGWLELSVVNAATSVAVSGDRRAVSAAVARVREQGRFAREITVGFPVHTSIL----EPL 299 Query: 307 RAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRD 366 R QL F D+ + +G G + + GDYW+ NLR +VRFD+A +A + Sbjct: 300 RDDFVKQLPQAVFADSPVQFIGGATGDVVPAGAMFGDYWYANLRTMVRFDRAFESARRCG 359 Query: 367 VETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHD 426 TFVEL+ HP L L A+ D D A +VG+ R + NLA AV D Sbjct: 360 ATTFVELSAHPQL-------LFAMGDLLGDTTATLVGSGRRDTPITEALSDNLAVAAVSD 412 Query: 427 LNYPWE----------------CLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLP 468 + W +RA P AQ PL + + + + +W P D+V P Sbjct: 413 PGHGWRDAVERTAHRLRGFPNAPMRATPLWAQPEPLSETADITVAQ-EVWQPIDDVTP 469 Score = 199 bits (506), Expect = 2e-48 Identities = 161/490 (32%), Positives = 224/490 (45%), Gaps = 39/490 (7%) Query: 551 GTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTG--VTDCWLVTVGGEAA 608 GT + +V++ P+ D + A V + A G D WLVT G E Sbjct: 506 GTPDTADVMVVVAPQPGGADAKTAVTTVTDLVGSGALRYPASAGPRCRDIWLVTAGAERV 565 Query: 609 TAADGPPDPVHAAASAGF-RSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAALHTANEPE 667 A G P + AAA A RS+G E+P +GF HLDLPA T +V L T E Sbjct: 566 RA--GEPQALSAAAIAAMHRSLGLENPELGFHHLDLPADPTIDT---AVVDTLLTG-AGE 619 Query: 668 LAYRDG---AFYAKRIXXXXXXXXXXXXX-CPEHVLIIGGTGNLGLEFCDHFAHRGARRI 723 LA R G Y + + + V+I GG G +GL + H A RGARRI Sbjct: 620 LAIRGGDGPVLYRRTVADAPVAPAWSLGSGILDEVVITGGAGRIGLHYARHLAERGARRI 679 Query: 724 TLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIHAAV 783 L+SR AV LA+L + ++ CD+ D ++ R A A L+IHAA Sbjct: 680 VLLSRRAVDPAV---LAELTAPRGTEVVSVPCDLTDRESI-RTATDFAGIGASLVIHAAG 735 Query: 784 AYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQVMYA 843 A E + A N L AKV G+ + D +P RIVLCSS GG G +Y+ Sbjct: 736 AATFAEGDRLDAAAAVNTLGAKVTGLAHLADLWPLHPDARIVLCSSVSGLWGGHGHAVYS 795 Query: 844 AANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFD---LDASSMAQLAAIGVIPMPPAEAIA 900 AANRMLDAMA RLRA+G CVSV+WG W + A+ A++ G+ PM P AI Sbjct: 796 AANRMLDAMAGRLRADGHRCVSVRWGLWRSDSGEGIVGAAETARIERSGLRPMAPLPAIE 855 Query: 901 LGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSE------TAAPAEPADLPG 954 + + +V + D R + + S PV + TAAP + AD Sbjct: 856 ASLCDHTVDPLVFSADPHRMQ----------MFSAATEPVRDPQTAETTAAPVDTAD--- 902 Query: 955 RLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASI 1014 + D + LG+DSL AL+L +R + + ++ LLGG + Sbjct: 903 AVRAELAAVLKITDPGGIDLDASLFDLGVDSLLALDLGKRFRRVLGRTVPLATLLGGVTG 962 Query: 1015 ADVLAQLGSR 1024 A+++A+L + Sbjct: 963 AELVAELDEK 972 >tr|A4F5D7|A4F5D7_SORCE Tax_Id=56 (spiE)SubName: Full=Polyketide synthase;[Sorangium cellulosum] Length = 3426 Score = 175 bits (443), Expect = 3e-41 Identities = 134/457 (29%), Positives = 198/457 (43%), Gaps = 20/457 (4%) Query: 10 DGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTR 69 D + LLSA T + L ++A LR H+AA PDL ++ L R Sbjct: 2030 DSALLFLLSAKTDDALRAQADRLRAHLAAAPDLALADVALSLATTRSHFECRAAIVAKDR 2089 Query: 70 AELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEV 129 L+ AL A+ P RT AA ++ +VF E+ FR ++ Sbjct: 2090 DALLTALDALARGAPAPDA-RTGDAACSGKVAFVFPGQGSQWPEMAASLLETDAVFREQI 2148 Query: 130 DRCAQAFEAQSCGSPRNYLLDKNFQDDGSA-----GIVQPALFTQMAALAAMWRSFGIAP 184 + C +A S L + + +A +VQP LF M ALAA WR+ G+ P Sbjct: 2149 EACERALAPHVAWSLGAVLRGEAVGGETAAPLDRVDVVQPVLFAVMVALAASWRAMGVEP 2208 Query: 185 NVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLL 244 + +GHSQGE+AAAYV+G ++LEDA +V+ +R + E L Sbjct: 2209 DAVVGHSQGEIAAAYVAGALSLEDAAKVVALR-ARAITKIAGRGAMAAVELSADELEARL 2267 Query: 245 ARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGAD 304 A G ++ +NSPR ++G+ + + +V L FAR +RV Y +H++ + + Sbjct: 2268 AAFDGRVSIAAINSPRATLVAGDVDAIDALVGDLGAAQIFARKVRVDYASHSAHV----E 2323 Query: 305 KLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQ 364 + A + +L + + A GA + YW+ NLR VRF+ A A + Sbjct: 2324 AIEADLATELAGITPRACVVPLYSAVTGAKLDGTALDAAYWYRNLRQTVRFEDATRALLA 2383 Query: 365 RDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAV 424 FVE++ HP L LA+ E EA A VVGT R D LA+L Sbjct: 2384 DQHRFFVEVSPHPVLGLALGET-----SEAVGASAAVVGTLRRDEGDRARLLLALAELHA 2438 Query: 425 HDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 + WE EP GA+ + L P R WL Sbjct: 2439 RGREHAWEAF-FEPLGARRVAL---PTYAFQRERFWL 2471 Score = 173 bits (439), Expect = 1e-40 Identities = 134/465 (28%), Positives = 200/465 (43%), Gaps = 26/465 (5%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRA 70 G +P LLSA T L ++AT L HVA PD+ ++A L RA Sbjct: 470 GALPFLLSAKTEAALRAQATRLHAHVARDPDVALVDVAASLATTRSHFERRAAVVADDRA 529 Query: 71 ELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVD 130 L+ AL A+ + + + A ++ +VF S PAFRAE++ Sbjct: 530 ALLSALAALAEGRAGAGTVAGE-ALPPGKVAFVFPGQGSQWPSMARALLASSPAFRAEIE 588 Query: 131 RCAQAFEAQSCGSPRNYLLDKNFQDDGSAG-------IVQPALFTQMAALAAMWRSFGIA 183 C +A S LL D+ A +VQP LF M ALAA WR+ G+ Sbjct: 589 ACERALAPHVDWS----LLAVLGGDEAHAAPMLERVDVVQPVLFAVMIALAATWRAAGVT 644 Query: 184 PNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDL 243 P+ +GHSQGE+AAAYV+G ++LEDA RV+ +R + E Sbjct: 645 PDAVVGHSQGEIAAAYVAGALSLEDAARVVALRSRAITKLAGRGAMAAVELTTAD-LEAR 703 Query: 244 LARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGA 303 LA G ++ +NSP +SG+ + + +V L+ FAR +RV Y +H++ + Sbjct: 704 LAPFGGRLAIAAINSPHAALVSGDPDAIDELVAELSGAQLFARKVRVDYASHSAHVEAIE 763 Query: 304 DKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAV 363 L A+ P+ + A G + E +W+ NLR+ VRF+ A A + Sbjct: 764 RTLLEALDGIAPRPA----TVPLYSAVTGERLDGEALGAAHWYRNLRHTVRFEHATRALL 819 Query: 364 QRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLA 423 FVE++ HP L +A+ + + +A A+ + R DL F +LA+L Sbjct: 820 DDGHRFFVEVSPHPVLTVALRDTI-----DASGHDAVACASLRRDEGDLARFNLSLAELH 874 Query: 424 VHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLP 468 L W A P + + L P R WL E P Sbjct: 875 TRGLAVDWRAFFA-PFAPRTVAL---PTYAFQRERFWLDAPEARP 915 Score = 128 bits (321), Expect = 5e-27 Identities = 123/443 (27%), Positives = 173/443 (39%), Gaps = 38/443 (8%) Query: 592 DTGVT-DCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLD----LPAG 646 D G+T WL T G + +AD P A R +G EHP +D L AG Sbjct: 1092 DAGITAPLWLFTRGAVSIGSADRLTRPAQAMTWGLGRVVGLEHPERWGGLVDVGEALGAG 1151 Query: 647 AT--AQDWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIG 702 + A+ AH + +E +A R +A+R+ +L+ G Sbjct: 1152 SALGARGLAHLVAWIAQRGDEDHVALRPAGLFARRLVRAPLGEAPAIRKLAPRGAILVTG 1211 Query: 703 GTGNLGLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAA 762 GTG +G A GA + L SR G +A AE L +A A++ + CDV D A Sbjct: 1212 GTGAIGAHVARWLAEHGAEHVVLTSRRGAAAPGAEALRDELTARGARVTIAACDVADREA 1271 Query: 763 VSRLAAQHRST-PADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDG 821 ++ L + P + HA + D +A+ K G + + F Sbjct: 1272 IAALVRDVEAEGPVTAVFHAGGVGPQAAIAATDIADLADAVAGKAAGARHLDELFGDRAL 1331 Query: 822 CRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDL--DA 879 VL SS GG Q YAAAN LDA+A RA GL SV WG W L +A Sbjct: 1332 DAFVLFSSGAGVWGGGQQGAYAAANAFLDALAEERRARGLAATSVAWGAWAGGGMLAENA 1391 Query: 880 SSMAQLAAIGVIPMPP---AEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSEL 936 + A+L +G PM P A+A ++ + VA D+ R P + PL+ E+ Sbjct: 1392 EADARLRRMGFSPMAPPLAVAALARALEHDETSVAVADIDWARFAPSFASARPRPLIGEI 1451 Query: 937 LSPVSETAAPAEPADLP----------------GRLSNXXXXXXXXXXXXXXDTSVPMVA 980 A AEPA P RL + + Sbjct: 1452 AEARRALDALAEPAAAPHGEPPLLAALRALDEVDRLPHLVALVLAETAAVLGHADASRIE 1511 Query: 981 -------LGLDSLQALELRRRVK 996 LGLDSL ++ELRRR++ Sbjct: 1512 PHRGFFDLGLDSLMSVELRRRLR 1534 Score = 116 bits (291), Expect = 1e-23 Identities = 126/438 (28%), Positives = 171/438 (39%), Gaps = 39/438 (8%) Query: 592 DTGVTDCWLVTVGGEA-ATAADGPP-DPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATA 649 D + C LV + A AT D D HA R+ AE P +D Sbjct: 2882 DERLAPCALVVLTTRAIATRPDEDVRDLAHAPLWGLVRAAQAERPDRAIFVVD----TDG 2937 Query: 650 QDWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNL 707 + +H +AA EP+LA R G A R+ + VL+ GGTG L Sbjct: 2938 EGASHRALAAALDGAEPQLALRGGRRLAPRLARATTAAAPPPRALDPNGTVLVTGGTGAL 2997 Query: 708 GLEFCDHFAH-RGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRL 766 G H G + L SR+G A AE L + A A++ + CDV A+ L Sbjct: 2998 GALVARHLVEGHGITNLLLTSRTGPDAPGAEALRRDLEARGARVTIAACDVASRPALDAL 3057 Query: 767 AAQ-HRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIV 825 R P I+HAA A A +T D+ AKV G + + D V Sbjct: 3058 VGSIPREHPLTAIVHAAGATADGVIGALTRDELAVVFRAKVDGALHLHEITRERDLAAFV 3117 Query: 826 LCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDA----SS 881 L SSA IGG G YAAAN LDA+A R RA GL S+ WG W + A + Sbjct: 3118 LFSSASGVIGGPGMANYAAANTFLDALAQRRRALGLPASSLAWGYWDQSTGMSARVGPAL 3177 Query: 882 MAQLAAIGVIPMPPAEAIAL---GMQRLGRNAIVAAF---------------DFDRARPV 923 A++ G+ + + +AL + + + A F R R Sbjct: 3178 RARMGRGGLRALSAEDGLALFDVALSHPDASLVPARFAAIADGTDALSPLLRGLARPRAA 3237 Query: 924 LETFGYG----PLVSELLSPVSETAAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSVPMV 979 + G G L E ++ +SE AD+ + D P+ Sbjct: 3238 RRSGGAGAAQAALAPERIAGLSEAERERAVADV---VRGEIAAVLGYRTPSELDVDRPLR 3294 Query: 980 ALGLDSLQALELRRRVKA 997 +GLDSL ALELRRR+ A Sbjct: 3295 EIGLDSLMALELRRRLAA 3312 >tr|Q53840|Q53840_SORCE Tax_Id=56 (sorB)SubName: Full=Soraphen polyketide synthase B;[Sorangium cellulosum] Length = 8817 Score = 171 bits (433), Expect = 5e-40 Identities = 134/456 (29%), Positives = 200/456 (43%), Gaps = 30/456 (6%) Query: 14 PVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAELI 73 PVLLSA + + ++A LRDH+ AH DLT ++ L R EL+ Sbjct: 7225 PVLLSARSEAAVRAQAKRLRDHLVAHDDLTLADVAYSLATTRAHFEHRAALVAHNRDELL 7284 Query: 74 DALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRCA 133 AL ++ P+ + + ++ +VF +S P FRA+++ C Sbjct: 7285 SALDSLAQDKPAPSTV-LGRSGSHGKLVFVFPGQGSQWEGMALSLLDSSPVFRAQLEACE 7343 Query: 134 QAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAMWRSFGIAPNVTI 188 +A S LL +D+G+ +VQPALF M +LAA+WRS G+ P + Sbjct: 7344 RALAPHVEWS----LLAVLRRDEGAPSLDRVDVVQPALFAVMVSLAALWRSLGVEPAAVV 7399 Query: 189 GHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCS 248 GHSQGE+AAA+V+G ++LEDA R+ +R DL + Sbjct: 7400 GHSQGEIAAAFVAGALSLEDAARIAALRSKALTTVAGNGAMAAVELG----ASDLQTYLA 7455 Query: 249 GWA---QLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADK 305 W ++ VNSPR +SGE + ++D+LT FAR +RV Y +H++ + D+ Sbjct: 7456 PWGDRLSIAAVNSPRATLVSGEPAAIDALIDSLTAAQVFARKVRVDYASHSAQMDAVQDE 7515 Query: 306 LRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQR 365 L A + + + G L SEL G YW+ NLR V F A + Sbjct: 7516 LAAGLANIAPRTCELPLYSTVTGTRLDG---SELD-GAYWYRNLRQTVLFSSATERLLDD 7571 Query: 366 DVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVH 425 FVE++ HP L LA+ E E +VVG+ R L + A+L+ Sbjct: 7572 GHRFFVEVSPHPVLTLALRETC-----ERSPLDPVVVGSIRRDEGHLARLLLSWAELSTR 7626 Query: 426 DLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L W A P + + L +P R R WL Sbjct: 7627 GLALDWNAFFA-PFAPRKVSLPTYPFQRE---RFWL 7658 Score = 170 bits (431), Expect = 8e-40 Identities = 131/453 (28%), Positives = 204/453 (45%), Gaps = 26/453 (5%) Query: 14 PVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAELI 73 PVLLSA + + ++A LRDH+ AH DL ++ L R EL+ Sbjct: 5671 PVLLSARSEPAVRAQAQRLRDHLLAHDDLALADVAYSLATTRATFEHRAALVVHDREELL 5730 Query: 74 DALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRCA 133 AL ++ P+ + + + ++ +VF ++ P FRA+++ C Sbjct: 5731 SALDSLAQGRPAPSTV-VERSGSHGKVVFVFPGQGSQWEGMALSLLDTSPVFRAQLEACE 5789 Query: 134 QAFEAQSCGSPRNYLLDKNFQDDGS-----AGIVQPALFTQMAALAAMWRSFGIAPNVTI 188 +A S LL ++G+ +VQPALF+ M +LAA+WRS G+ P+ + Sbjct: 5790 RALAPHVDWS----LLAVLRGEEGAPPLDRVDVVQPALFSMMVSLAALWRSMGVEPDAVV 5845 Query: 189 GHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCS 248 GHSQGE+AAA V+G ++LEDA +++ +R + E L R Sbjct: 5846 GHSQGEIAAACVAGALSLEDAAKLVALRSRALVELAGQGAMAAVELPEAEVAR-RLQRYG 5904 Query: 249 GWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLRA 308 + +NSPR ISGE V ++ L G FA + + +H++ + + +R Sbjct: 5905 DRLSIGAINSPRFTTISGEPPAVAALLRDLESEGVFALKLSYDFASHSAQV----ESIRD 5960 Query: 309 AIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDVE 368 + D L T + GA I YW+ NLR VRF A+ + + Sbjct: 5961 ELLDLLSWLEPRSTAVPFYSTVSGAAIDGSELDAAYWYRNLRQPVRFADAVQGLLAGEHR 6020 Query: 369 TFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHDLN 428 FVE++ P L LA+HE L EA +R A VVG+ DL F +L++L V+ Sbjct: 6021 FFVEVSPSPVLTLALHELL-----EASERSAAVVGSLWSDEGDLRRFLVSLSELYVNGFA 6075 Query: 429 YPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 W + P G + +PL +P R R WL Sbjct: 6076 LDWTTIL--PPG-KRVPLPTYPFQRE---RFWL 6102 Score = 157 bits (396), Expect = 9e-36 Identities = 139/479 (29%), Positives = 202/479 (42%), Gaps = 32/479 (6%) Query: 2 SAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXX 61 S A R VLLSA + + ++A LRDH+ AH DL ++ Sbjct: 2027 SQTASRPLPAACAVLLSARSEAAVRAQAKRLRDHLLAHDDLALIDVAYSQATTRAHFEHR 2086 Query: 62 XXXXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYES 121 R EL+ AL ++ P+ + + ++ +VF +S Sbjct: 2087 AALLARDRDELLSALDSLAQDKPAPSTV-LGRSGSHGKVVFVFPGQGSQWEGMALSLLDS 2145 Query: 122 VPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAM 176 P FRA+++ C +A S LL +D+G+ +VQPALF M +LAA+ Sbjct: 2146 SPVFRAQLEACERALAPHVEWS----LLAVLRRDEGAPSLDRVDVVQPALFAVMVSLAAL 2201 Query: 177 WRSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXD 236 WRS G+ P +GHSQGE+AAA+V+G ++LEDA R+ +R Sbjct: 2202 WRSLGVEPAAVVGHSQGEIAAAFVAGALSLEDAARIAALRRKALTTVGGNGGMAAVELG- 2260 Query: 237 RETCEDLLARCSGWA---QLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYP 293 DL + W + VNSPR +SGE V ++D LT FAR IRV Y Sbjct: 2261 ---ASDLQTYLAPWGDRLSTAAVNSPRATLVSGEPAAVDALLDVLTATKVFARKIRVDYA 2317 Query: 294 AHTSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIV 353 +H++ + D+L A + + + G L SEL G YW+ NLR V Sbjct: 2318 SHSAQMDAVQDELAAGLANIAPRTCELPLYSTVTGTRLDG---SELD-GAYWYRNLRQTV 2373 Query: 354 RFDKAIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLG 413 F A + VE++ HP L LA+ E E +VVG+ R L Sbjct: 2374 LFSSATERLLDDGHRFSVEVSPHPVLTLALRETC-----ERSPLDPVVVGSIRREEGHLA 2428 Query: 414 EFTRNLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPY--DEVLPRR 470 + A+L+ L W+ A P + + L +P R R WL DE RR Sbjct: 2429 RLLLSWAELSTRGLALDWKDFFA-PYAPRKVSLPTYPFQRE---RFWLDVSTDERFRRR 2483 Score = 157 bits (396), Expect = 9e-36 Identities = 124/417 (29%), Positives = 185/417 (44%), Gaps = 30/417 (7%) Query: 14 PVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAELI 73 PV+LSA + + ++A LR+H+ A DLT ++ L R EL+ Sbjct: 4115 PVVLSARSEAAVRAQAQRLREHLLAQGDLTLADVAYSLATTRAHFEHRAALVAHDRDELL 4174 Query: 74 DALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRCA 133 AL ++ P+ + + ++ +VF +S P FR +++ C Sbjct: 4175 SALDSLAQDKPAPSTV-LGRSGSHGKVVFVFPGQGSQWEGMALSLLDSSPVFRTQLEACE 4233 Query: 134 QAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAMWRSFGIAPNVTI 188 +A S LL +D+G+ +VQPALF M +LAA+WRS G+ P + Sbjct: 4234 RALRPHVEWS----LLAVLRRDEGAPSLDRVDVVQPALFAVMVSLAALWRSLGVEPAAVV 4289 Query: 189 GHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCS 248 GHSQGE+AAA+V+G ++LEDA R+ +R DL + Sbjct: 4290 GHSQGEIAAAFVAGALSLEDAARIAALRSKASPPSPATGMAAVELG-----ASDLQTYLA 4344 Query: 249 GWA---QLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADK 305 W ++ VNSPR +SGE V ++D+LT FAR +RV Y +H++ + D+ Sbjct: 4345 PWGDRLSIAAVNSPRATLVSGEPAAVDALIDSLTAAQVFARRVRVDYASHSAQMDAVQDE 4404 Query: 306 LRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQR 365 L A + + + G L SEL G YW+ NLR V F A + Sbjct: 4405 LAAGLANIAPRTCELPLYSTVTGTRLDG---SELD-GAYWYRNLRQTVLFSSATERLLDD 4460 Query: 366 DVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQL 422 FVE++ HP L LA+ E E +VVG+ R D G R LA L Sbjct: 4461 GHRFFVEVSPHPVLTLALRETC-----ERSPLDPVVVGSIRR---DEGHLPRLLALL 4509 Score = 117 bits (293), Expect = 8e-24 Identities = 116/428 (27%), Positives = 160/428 (37%), Gaps = 30/428 (7%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVA 658 WL T G + +D P A R +G EHP +DL A A + A Sbjct: 4740 WLFTRGAVSIGHSDPLAHPTQAMIWGLGRVVGLEHPERWGGLVDLGAALDASAAGRLLPA 4799 Query: 659 ALHTANEPELAYRDGAFYAKR-IXXXXXXXXXXXXXCPEH-VLIIGGTGNLGLEFCDHFA 716 +E +LA R YA+R + P +LI GGTG +G A Sbjct: 4800 LAQRHDEDQLALRPAGLYARRFVRAPLGDAPAARGFMPRGTILITGGTGAIGAHVARWLA 4859 Query: 717 HRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQ--HRSTP 774 +GA + L+SR G A A L +A A++ CDV D +AV+ L Q Sbjct: 4860 RKGAEHLVLISRRGAQAEGAVELHAELTALGARVTFAACDVADRSAVATLLEQLDAGGPQ 4919 Query: 775 ADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATI 834 + HA + + +D + KV G + D VL SS Sbjct: 4920 VSAVFHAGGIEPHAPLAATSMEDLAEVVSGKVQGARHLHDLLGSRPLDAFVLFSSGAVVW 4979 Query: 835 GGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMP 894 GG Q YAAAN LDA+A + R+ GL SV WG W AQL G+ PM Sbjct: 4980 GGGQQGGYAAANAFLDALAEQRRSLGLTATSVAWGVWGGGGMATGLLAAQLEQRGLSPMA 5039 Query: 895 PAEAI---ALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPAEPAD 951 P+ A+ AL ++ VA D+ R P PL+ +L A A+ + Sbjct: 5040 PSLAVATLALALEHDETTLTVADIDWARFAPSFSAARSRPLLRDLPEAQRALEASADASS 5099 Query: 952 -----------------------LPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQA 988 L + + D + LGLDSL Sbjct: 5100 EQDGATGLLDKLRNRSESEQIHLLSSLVRHEAALVLGHTDASQVDPHKGFMDLGLDSLMT 5159 Query: 989 LELRRRVK 996 +ELRRR++ Sbjct: 5160 VELRRRLQ 5167 Score = 117 bits (292), Expect = 1e-23 Identities = 120/430 (27%), Positives = 163/430 (37%), Gaps = 34/430 (7%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVA 658 W T G + +D P A R IG EHP +D+ AG + A Sbjct: 1108 WFFTRGAVSIGHSDPLAHPAQAMTWGLGRVIGLEHPDRWGGLVDVCAGVDESAVGRLLPA 1167 Query: 659 ALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLEFCDHFA 716 +E +LA R YA+RI +LI GGTG +G A Sbjct: 1168 LAERHDEDQLALRPAGLYARRIVRAPLGDAPPARDFTPGGTILITGGTGAIGAHVARWLA 1227 Query: 717 HRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPAD 776 RGA+ + L+SR G A A L SA A+ + CDV D AV+ L Q + + Sbjct: 1228 RRGAQHLVLISRRGAEAPGASELHDELSALGARTTLAACDVADRNAVATLLEQLDAEGSQ 1287 Query: 777 L--IIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATI 834 + + HA+ + D + KV G + D VL SS A Sbjct: 1288 VRAVFHASGIEHHAPLDATSFRDLAEVVSGKVEGAKHLHDLLGSRPLDAFVLFSSGAAVW 1347 Query: 835 GGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMP 894 GG Q YAAAN LDA+A R+ GL SV WG W + A L G+ M Sbjct: 1348 GGGQQGGYAAANAFLDALAEHRRSAGLTATSVAWGAWGGGGMATDQAAAHLQQRGLSRMA 1407 Query: 895 PA---EAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETA------A 945 P+ A+AL ++ VA D+ R P PL+ +L P ++ A A Sbjct: 1408 PSLALAALALALEHDETTVTVADIDWARFAPSFSAARPRPLLRDL--PEAQRALETSEGA 1465 Query: 946 PAEPADLPGRLS-------------------NXXXXXXXXXXXXXXDTSVPMVALGLDSL 986 +E P L + D + LGLDSL Sbjct: 1466 SSEHGPAPDLLDKLRSRSESEQLRLLVSLVRHETALVLGHEGASHVDPDKGFLDLGLDSL 1525 Query: 987 QALELRRRVK 996 A+ELRRR++ Sbjct: 1526 MAVELRRRLQ 1535 Score = 115 bits (289), Expect = 2e-23 Identities = 108/432 (25%), Positives = 164/432 (37%), Gaps = 24/432 (5%) Query: 14 PVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAELI 73 PVLLSA + + ++A LRDH+ A +L ++ L R EL+ Sbjct: 478 PVLLSAKSEAAVRAQAKRLRDHLLAKSELALADVAYSLATTRAHFEQRAALLVKGRDELL 537 Query: 74 DALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRCA 133 AL A+ + L R+ ++ +F Y+ P FR +D Sbjct: 538 SALDALAQGHSAAVLGRSGAPG---KLAVLFTGQGSQRPTMGRGLYDVFPVFRDALDTVG 594 Query: 134 QAFEAQSCGSPRNYLLDKNFQDDGS--------AGIVQPALFTQMAALAAMWRSFGIAPN 185 + + R+ L F DGS QPALF AL + +SFG+ P Sbjct: 595 AHLDRELDRPLRDVL----FAPDGSEQAARLEQTAFTQPALFALEVALFQLLQSFGLKPA 650 Query: 186 VTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLA 245 + +GHS GE+ AA+V+G ++L+D ++ R + E DLL Sbjct: 651 LLLGHSIGELVAAHVAGVLSLQDGCTLVAARAKLMQALPQGGAMVTLRASEEEV-RDLLQ 709 Query: 246 RCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADK 305 G A L+ +N P ++G+ + V I G +RV + H+ + D Sbjct: 710 PYEGRASLAALNGPLSTVVAGDEDAVVEIARQAEALGRKTTRLRVSHAFHSPHMDGMLDD 769 Query: 306 LRAAIQDQLQHPSFVDTDIDCLGATLGAPITS-ELPVGDYWFWNLRNIVRFDKAIAAAVQ 364 R Q HP+ I + GA T EL DYW ++R+ VRF + A Sbjct: 770 FRRVAQSLTYHPA----RIPIISNVTGARATDHELASPDYWVRHVRHTVRFLDGVRALHA 825 Query: 365 RDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAV 424 F+EL H L + AL + P + T + D FT L L Sbjct: 826 EGARVFLELGPHAVLSALAQD---ALGQDEGTSPCAFLPTLRKGRDDAEAFTAALGALHS 882 Query: 425 HDLNYPWECLRA 436 + W A Sbjct: 883 AGITPDWSAFFA 894 Score = 115 bits (288), Expect = 3e-23 Identities = 98/326 (30%), Positives = 133/326 (40%), Gaps = 26/326 (7%) Query: 698 VLIIGGTGNLGLEFCDHF-AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCD 756 VLI GGTG LG+ H A A+ + L SR G A AE L A A + + CD Sbjct: 3299 VLITGGTGTLGVLVARHLVAKHSAKHLLLTSRKGARAPGAEALRSELEALGASVTLVACD 3358 Query: 757 VGDPAAVSRLAAQ-HRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDA 815 V DP A+ L R P ++HAA A ++ + K+ + + Sbjct: 3359 VADPRALRTLLDSIPRDHPITAVVHAAGALDDGPLGSMSAERIARVFDPKLDAAWYLHEL 3418 Query: 816 FPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT--- 872 VL S+A +GG GQ YAAAN LDA+AH RA+GL S+ WG W Sbjct: 3419 TQDEPVAAFVLFSAASGVLGGPGQSNYAAANAFLDALAHHRRAQGLPAASLAWGYWAERS 3478 Query: 873 -VHFDLDASSMAQLAAIGVIPMPPAEAIAL---GMQRLGRNAIVAAFDFD---------- 918 + L A+ A++ GV P+ EA++L + R + A FD++ Sbjct: 3479 GMTRHLSAADAARMRRAGVRPLDTDEALSLFDVALLRPEPALVPAPFDYNVLSTSADGVP 3538 Query: 919 -------RARPVLETFGYGPLVSELLSPVSETAAPAEPADLPGRLSNXXXXXXXXXXXXX 971 RAR + L S L +S L + Sbjct: 3539 PLFQRLVRARIARKAASNTALASSLAEHLSSLPPAERERVLLDLVRTEAASVLGLASFES 3598 Query: 972 XDTSVPMVALGLDSLQALELRRRVKA 997 D P+ LGLDSL ALELR R+ A Sbjct: 3599 LDPHRPLQELGLDSLMALELRNRLAA 3624 Score = 107 bits (268), Expect = 7e-21 Identities = 115/432 (26%), Positives = 161/432 (37%), Gaps = 37/432 (8%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVA 658 WL T G + +D P A R +G EHP +D+ A A + Sbjct: 6295 WLFTRGAVSVGHSDPIAHPTQAMTWGLGRVVGLEHPERWGGLVDVGAAIDASAVGRLLPV 6354 Query: 659 ALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLEFCDHFA 716 +E +LA R FYA+R+ +LI GGTG G A Sbjct: 6355 LALRNDEDQLALRPAGFYARRLVRAPLGDAPPARTFKPRGTLLITGGTGAAGAHVARWLA 6414 Query: 717 HRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQ--HRSTP 774 GA + L+SR G A A L +A A++ CDV D +AV+ L Q + Sbjct: 6415 REGAEHLVLISRRGAQAEGASELHAELTALGARVTFAACDVADRSAVATLLEQLDAEGSQ 6474 Query: 775 ADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATI 834 + HA + + + + + AKV+G G + D VL SS Sbjct: 6475 VRAVFHAGGIGRHAPLAATSLMELADVVSAKVLGAGNLHDLLGPRPLDAFVLFSSIAGVW 6534 Query: 835 GGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSM-AQLAAIGVIPM 893 GG Q YAA N LDA+A + R+ G SV WG W + + AQL + PM Sbjct: 6535 GGGQQAGYAAGNAFLDALADQRRSLGQPDTSVVWGAWGGGGGIFTGPLAAQLEQRRLSPM 6594 Query: 894 PPAEAIALGMQRLGRN---AIVAAFDFDRARPVLETF----------GYGPLVSELLSPV 940 P+ A+A Q L + VA D+ R P + P +E P Sbjct: 6595 APSLAVAALAQALEHDETTVTVADIDWARFAPSISVARSRRSCATCPSSAPSKTEKARPP 6654 Query: 941 SETAAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSVPMVA----------------LGLD 984 T A P DL +L + +V LGLD Sbjct: 6655 PST---ARPPDLLDKLRSRSESEQLRLLAALVCDETALVLGHEGRFPARPRQGFFDLGLD 6711 Query: 985 SLQALELRRRVK 996 S+ +ELRRR++ Sbjct: 6712 SIMTVELRRRLQ 6723 Score = 97.1 bits (240), Expect = 1e-17 Identities = 113/428 (26%), Positives = 157/428 (36%), Gaps = 37/428 (8%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAA 659 LVT A A + HA RS +EHP +DL +Q H ++ A Sbjct: 8067 LVTRRAVATHAEEDVKGLAHAPLWGLARSAQSEHPERPLVLVDLDDSEASQ---HALLGA 8123 Query: 660 LHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCP--EHVLIIGGTGNLGLEFCDHFA- 716 L A EPE+A R+G R+ VLI GGTG LG Sbjct: 8124 LD-AREPEIALRNGKPLVPRLSRLPQAPTDTASPAGLGGTVLITGGTGTLGALVARRLVV 8182 Query: 717 HRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRST-PA 775 + A+ + L SR G SA A+ L A A + + CDV DP A+ L S P Sbjct: 8183 NHDAKHLLLTSRQGASAPGADVLRSELEALGASVTLAACDVADPRALKDLLDNIPSAHPV 8242 Query: 776 DLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIG 835 ++HAA ++ + D K+ + +L SS +G Sbjct: 8243 AAVVHAASVLDGDLLGAMSLERIDRVFAPKIDAAWHLHQLTQDKPLAAFILFSSVAGVLG 8302 Query: 836 GRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW------TVHFDLDASSMAQLAAIG 889 G YAAA+ LDA+AH RA+GL S+ W W T H + A+ ++ G Sbjct: 8303 SSGHSNYAAASAFLDALAHHRRAQGLPASSLAWSHWAERSAMTEH--VSAAGAPRMERAG 8360 Query: 890 VIPMPPAEAIAL---GMQRLGRNAIVAAFDFD-----------------RARPVLETFGY 929 +P E +AL + R + A FD RAR V + Sbjct: 8361 -LPSTSEERLALFDAALFRTETALVPARFDLSALRANAGSVPPLFQRLVRARTVRKAASN 8419 Query: 930 GPLVSELLSPVSETAAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQAL 989 S L +S L + D + LGLDS+ AL Sbjct: 8420 TAQASSLTERLSALPPAERERALLDLIRTEAAAVLGLASFESLDPDRLLQELGLDSIIAL 8479 Query: 990 ELRRRVKA 997 +LR R+ A Sbjct: 8480 DLRNRLAA 8487 >tr|Q3S864|Q3S864_9ACTO Tax_Id=42238 SubName: Full=Nodular polyketide synthase;[Streptomyces neyagawaensis] Length = 4970 Score = 170 bits (431), Expect = 8e-40 Identities = 139/465 (29%), Positives = 198/465 (42%), Gaps = 37/465 (7%) Query: 9 PDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXT 68 P +P LLS TPE L +A L H+ P+L P + L Sbjct: 2018 PGTAVPWLLSGRTPEALREQAARLHTHLTDRPELRPHDVGLTLATARSAFEHRAVVVGAD 2077 Query: 69 RAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 RA L+ L A+ PA++R A R + +VF +S P F Sbjct: 2078 RATLLTGLAALAAGENDPAVVRGTAATPGRTV-FVFPGQGSQWVGMAVGLLDSAPVFAER 2136 Query: 129 VDRCAQAFEAQSCGSPRNYL--------LDKNFQDDGSAGIVQPALFTQMAALAAMWRSF 180 + C +A S + L LD+ +VQP LF+ M +LAA+WRS+ Sbjct: 2137 IAECERALSPYLDWSLTDVLRAAPDSPPLDR-------VDVVQPVLFSMMVSLAALWRSY 2189 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P+ +GHSQGE+AAA V+G +TLED R++ R D E Sbjct: 2190 GVEPSAVVGHSQGEIAAAVVAGALTLEDGARIVARRSQILTALVGRGTMLFVALPDEEV- 2248 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 + LA +G ++ VN P V +SG+ E ++ + L+E G V+R P T H Sbjct: 2249 RERLAPWAGKLSVAAVNGPAAVTVSGDPEALEEFGERLSEDG----VMRWTIPGVTFAGH 2304 Query: 301 D-GADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAI 359 D++R + D L + TDI G + + +YW+ NLR V F + + Sbjct: 2305 SPQVDEVRGELLDALAGVAPRRTDIAFYSTVTGGVVDTTTLDTEYWYRNLREPVEFHRTV 2364 Query: 360 AAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNL 419 AA ++ +TFVE HP L + I +L EA D V GT TD G R L Sbjct: 2365 AALIEDGHDTFVETGPHPVLTVWIERSL-----EAADVTGRVTGT---LLTDDGGPDRFL 2416 Query: 420 AQLA---VHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 LA VH + W + A GA A P ++ P R WL Sbjct: 2417 TALAAPHVHGVPVDWSAVFA---GADARP-VELPTYAFQRQRYWL 2457 Score = 130 bits (327), Expect = 9e-28 Identities = 100/351 (28%), Positives = 152/351 (43%), Gaps = 34/351 (9%) Query: 120 ESVPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRS 179 ++ P F A + C +A S + L + D +VQP L+ M +LAA+WRS Sbjct: 580 DTSPVFAARMADCERALAPHVDWSLTDVL--SSATDLERVDVVQPVLWAVMVSLAALWRS 637 Query: 180 FGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRET 239 G+ P+ +GHSQGE+AAA V+G ++LED +V+ +R Sbjct: 638 AGVEPDAVLGHSQGEIAAAVVAGALSLEDGAKVVALRSQAITAIAGRGGMASVPLPP--- 694 Query: 240 CEDLLARCSGWA---QLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHT 296 E+L W ++ N P +SG+ E + GIV L AR I V Y +H+ Sbjct: 695 -EELAGHLGPWGDRLSVAAANGPAATVLSGDTEAIDGIVAQLQAEDVRARRIPVDYASHS 753 Query: 297 SLIHDGADKLRAAIQD------QLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLR 350 + + + ++L + D Q+ S VD + GA +YW+ NLR Sbjct: 754 AHVEEIRERLLECLADIEPTTGQVPFFSTVDLNWQDSGAL----------DAEYWYRNLR 803 Query: 351 NIVRFDKAIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTAT 410 VRF++A + + FVE + HP L + I + EA++ A+ VGT R Sbjct: 804 QTVRFEEATRTLLAQGFRFFVESSAHPVLTVGISQTA-----EAEESDAVAVGTLRRDQG 858 Query: 411 DLGEFTRNLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L F +LA+ L W+ L A G +D P R WL Sbjct: 859 GLDRFLLSLAEAHTGGLAPEWDTLLAGHPG----DTVDLPTYPFQRRRYWL 905 Score = 123 bits (308), Expect = 2e-25 Identities = 134/465 (28%), Positives = 179/465 (38%), Gaps = 38/465 (8%) Query: 592 DTGVT-DCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQ 650 D GVT W T G D P R EHP +DLP + Sbjct: 1088 DAGVTAPLWCATRGAVTTGRDDAVTSPGQHMVWGLGRCAALEHPQRWGGLVDLPDTLDER 1147 Query: 651 DWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLG 708 A +E ++A R Y +R+ VL+ GGTG +G Sbjct: 1148 AAARLCGILAGRDDEDQVAVRPSGAYGRRLVRARPADPARADAWQPRGTVLVTGGTGGVG 1207 Query: 709 LEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAA 768 A GA + LV R G A L +A ++ V CDV D ++ L A Sbjct: 1208 AHLARWLAKGGAEHLVLVGRRGADTPGAADLTAELTALGTRVTVAACDVADRDRLAELVA 1267 Query: 769 --QHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVL 826 + P +IHAA V SD D+ + LYAKV G + F R D VL Sbjct: 1268 GLEQDGPPIRTVIHAAGTGLLVPLSDTDPDEFADTLYAKVAGAENLDAVFDRDDLDTFVL 1327 Query: 827 CSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASS---MA 883 SS G YAAAN LDA+A R RA G SV WG W ++ Sbjct: 1328 FSSISGVWGSGDHGAYAAANAHLDALADRRRARGRTATSVVWGIWDPEGGAGMAANLVEE 1387 Query: 884 QLAAIGVIPMPPAEAIALGMQRLGRN----AIVAAFDFDRARPVLETFGYGPLVS---EL 936 QL G+ M P A+ G+Q++ + +V A D+DR PV + PL+ E+ Sbjct: 1388 QLRGRGIPFMAPQVALT-GLQQVLTDDETVVLVTAVDWDRFAPVFTSARPSPLIGDLPEV 1446 Query: 937 LSPVSETAAPAE-----------------PADLPGRLSN-XXXXXXXXXXXXXXDTSVPM 978 ++E APA+ PAD L++ D P Sbjct: 1447 RRALAEETAPAQDGDDTASSLRDRIADLPPADRDRLLTDLVRGHAAAVLGHGSADAIAPE 1506 Query: 979 VA---LGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQ 1020 A LG DSL A+E+R R+ A L ++ L AS AD LA+ Sbjct: 1507 RAFRELGFDSLTAVEMRNRLNAATGLRLPLTVLFDYAS-ADALAR 1550 Score = 118 bits (296), Expect = 4e-24 Identities = 128/455 (28%), Positives = 173/455 (38%), Gaps = 40/455 (8%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAA 659 LVT GG +A D HAA RS E+PG F DL D + + A Sbjct: 4438 LVTRGGVPVSADGVAQDLAHAAVWGLVRSAQTENPG-RFVLADL------DDASEDALVA 4490 Query: 660 LHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXC--PEHVLIIGGTGNLGLEFCDHFA- 716 + EP+LA R+G + R+ P VLI GGTG +G H A Sbjct: 4491 AVASGEPQLALREGRTHIARLTKVPVTEQPGTPDWGRPGTVLITGGTGAIGSVLARHLAA 4550 Query: 717 HRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRL-AAQHRSTPA 775 G +R+ L SR G +A A L +A A + CD D A++RL A Sbjct: 4551 EHGVKRLLLTSRRGPAAEGAADLVVELAALGAHAEIVACDAADRDALARLLGALPEDQSL 4610 Query: 776 DLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIG 835 ++HAA A +T D L KV + + D V+ SS G Sbjct: 4611 TAVVHAAGTIADGVVDAMTPVRLDTVLRPKVDAAWNLHELTEGMDLSAFVVFSSIAGVFG 4670 Query: 836 GRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLAAIGVI 891 G GQ YAAAN LDA+AH R GL S+ WG W + LD + ++A G+I Sbjct: 4671 GMGQGNYAAANSFLDALAHHRRQRGLPAASLAWGLWANKGGMSGGLDEADFRRIARGGII 4730 Query: 892 PMPPAEAIAL-GMQRLGRNAIVAAFDFDRARPVLET--FGYGPLVSELLSPVSETAAPA- 947 PAE AL +V D ++ G L+ L+ P + +A A Sbjct: 4731 AFSPAEGAALFDTANASSEPVVLPLRLDTTALAAQSGADGVPALLRGLVRPAARRSAAAG 4790 Query: 948 ----EPADLPGR-----------------LSNXXXXXXXXXXXXXXDTSVPMVALGLDSL 986 + AD R + D ++ LG DSL Sbjct: 4791 EAAPDAADTLRRTLAGQPEHRRLRTLLDLVRGHAAIVLGFPGPASVDAERGLLELGFDSL 4850 Query: 987 QALELRRRVKAEFDHELEVSDLLGGASIADVLAQL 1021 A+ELR R+ A L + L + V QL Sbjct: 4851 TAVELRNRLGAATGLRLPATLLFDHPTSGAVARQL 4885 Score = 111 bits (278), Expect = 5e-22 Identities = 128/468 (27%), Positives = 171/468 (36%), Gaps = 38/468 (8%) Query: 560 VILLPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVT-DCWLVTVGGEAATAADGPPDPV 618 ++ L E P DG A G + D G+ W VT G + +D P Sbjct: 2615 LLALAEQPYTDG--TALPTGLALTTTLLQALGDAGINAPLWSVTCGAVSVGRSDALTAPA 2672 Query: 619 HAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAALHTANEPELAYRDGAFYAK 678 A G E+P +DLPA + E ++A R Y + Sbjct: 2673 QATLWGLGAVAGVEYPERWAGLVDLPADLDDRSGGRLAAVLAGLDGEDQVAIRPSGIYGR 2732 Query: 679 RIXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLEFCDHFAHRGARRITLVSRSGESAAVA 736 R+ VLI GGTG LG A G R + L R G A Sbjct: 2733 RLVRALPGDETAPVAWKPDGTVLITGGTGALGAHVARRLARSGTRHLLLTGRRGPDTPGA 2792 Query: 737 ERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQ-HRSTPADLIIHAAVAYASVEFSDITT 795 L + A+ V CD D A++ L A P ++HAA +T Sbjct: 2793 AELVAELADLGAEARVAACDAADRDALAALLAGIPDDRPLRAVVHAAGVLDDGVLDTLTP 2852 Query: 796 DDADNALYAKVVGIGQVLDAFPRT-DGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAH 854 + A L K+ + LDA R D VL SS T+GG GQ YAAAN LDA+A Sbjct: 2853 ERAAGVLRPKM-DAARNLDALTRDLDLSAFVLFSSLAGTLGGTGQGSYAAANAYLDALAE 2911 Query: 855 RLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIALGMQRL--GRNAIV 912 R+ GL +V WG W + S+ QL G+ PM P A+ Q + G N ++ Sbjct: 2912 HRRSLGLPATAVAWGLWAGDSAAN-SAREQLVRNGIPPMDPELAVTALEQAVEQGENRLI 2970 Query: 913 AA-FDFDRARPVLETFGYGPLVSELLSPVSETAAPAEPAD--------LPGRLSNXXXXX 963 F +DR P ++ EL P + A AD L GRL+ Sbjct: 2971 LCDFAWDRFAPAYTALRPSAVLREL--PEARDILAAAGADGQDTGADSLAGRLAALSVQE 3028 Query: 964 XXXXXXXXXDTSVPMVA----------------LGLDSLQALELRRRV 995 T V V LG DSL A++LR R+ Sbjct: 3029 RQEELVRLIRTEVAAVLGYPDPADVDPDRVFKDLGFDSLTAVDLRNRL 3076 Score = 97.1 bits (240), Expect = 1e-17 Identities = 113/471 (23%), Positives = 173/471 (36%), Gaps = 36/471 (7%) Query: 10 DGTI-PVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXT 68 DGT+ P LLSA + L ++A L +H A P L P I+ L + Sbjct: 3576 DGTVLPWLLSARSRAALRAQAQRLLEHTDARPGLRPADIAHTLATGRSAFEYRGAVVGDS 3635 Query: 69 RAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFR-- 126 R L L+A+ P + T A+ ++ ++F Y P F Sbjct: 3636 REALTGGLKALATGGSAPGV--TQGTAVAGKVAFLFAGQGSQRAAMGAELYARYPVFADA 3693 Query: 127 -----AEVD----RCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMW 177 AE+D R + GS LLD+ QPALF AL + Sbjct: 3694 FDEICAELDPLLDRPLREVVFAPAGSDAAALLDRT-------EYTQPALFAVEVALFRLV 3746 Query: 178 RSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDR 237 +G+ P++ +GHS G +AAA+V+G T DA ++ R + Sbjct: 3747 EHWGVVPDLLLGHSIGVLAAAHVAGVFTAPDAAALVAARGRLMQALPEGGAMVALTASEA 3806 Query: 238 ETCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTS 297 + LLA G ++ VN P V +SG+ + V + + + G AR + V + H+ Sbjct: 3807 DATA-LLAPYDGRVAVAAVNGPASVVVSGDEDAVLDLAEQWRDRGGKARRLTVSHAFHSP 3865 Query: 298 LIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDK 357 + D+ R + + D G L P +L +YW ++R VRF Sbjct: 3866 HMDAMLDEFRRVAESLDYRAPRIPLVSDVTG-ELATP--EQLGSPEYWVRHVREAVRFHD 3922 Query: 358 AIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRP------AMVVGTSERTATD 411 + T++EL +L + A D P +V + T+ Sbjct: 3923 GMRRLAAEGAVTYLELGPDGSLTAMGRDCFAEADPIGSDDPVDPSAAGPLVPLLRKDRTE 3982 Query: 412 LGEFTRNLAQLAVHDLNYPW-ECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 T LAQL V W L A G Q ++ P R WL Sbjct: 3983 TRALTDALAQLYVRGTAVDWPTVLEATGRGGQ----VELPTYAFQRERYWL 4029 >tr|Q8GBX7|Q8GBX7_SORCE Tax_Id=56 (spiG)SubName: Full=Polyketide synthase; Flags: Fragment;[Sorangium cellulosum] Length = 2518 Score = 166 bits (420), Expect = 2e-38 Identities = 129/456 (28%), Positives = 197/456 (43%), Gaps = 26/456 (5%) Query: 13 IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAEL 72 +PVLLSA + L ++A L H+A H D+ ++A L RA L Sbjct: 1337 VPVLLSAKSDAALRAQAGKLHAHLAEHEDVALVDVAASLATTRSHFERRAAVVADDRAAL 1396 Query: 73 IDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRC 132 + AL A+ + + + A ++ +VF S PAFRAE++ C Sbjct: 1397 LSALAALAEGRAGAGTVAGE-ALPPGKVAFVFPGQGSQWPSMARALLASSPAFRAEIEAC 1455 Query: 133 AQAFEAQSCGSPRNYLLDKNFQDDGSAG-------IVQPALFTQMAALAAMWRSFGIAPN 185 +A S LL D+ A +VQP LF M ALAA WR+ G+ P+ Sbjct: 1456 ERALAPHVDWS----LLAVLGGDEAHAAPMLERVDVVQPVLFAVMIALAATWRAAGVTPD 1511 Query: 186 VTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLA 245 +GHSQGE+AAAYV+G ++LEDA RV+ +R + E LA Sbjct: 1512 AVVGHSQGEIAAAYVAGALSLEDAARVVALRSRAITKLAGRGAMAAVELTTAD-LEARLA 1570 Query: 246 RCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADK 305 G ++ +NSP +SG+ + + +V L+ FAR +RV Y +H++ + Sbjct: 1571 PFGGRLAIAAINSPHAALVSGDPDAIDELVAELSGAQLFARKVRVDYASHSAHVEAIERT 1630 Query: 306 LRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQR 365 L A+ P+ + A G + E +W+ NLR+ VRF+ A A + Sbjct: 1631 LLEALDGIAPRPA----TVPLYSAVTGERLDGEALGAAHWYRNLRHTVRFEHATRALLDD 1686 Query: 366 DVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVH 425 FVE++ HP L +A+ + + +A A+ + R DL F +LA+L Sbjct: 1687 GHRFFVEVSPHPVLTVALRDTI-----DASGHDAVACASLRRDEGDLARFNLSLAELHTR 1741 Query: 426 DLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L W A P + + L P R WL Sbjct: 1742 GLAVDWRAFFA-PFAPRTVAL---PTYAFQRERFWL 1773 Score = 127 bits (320), Expect = 6e-27 Identities = 132/441 (29%), Positives = 175/441 (39%), Gaps = 43/441 (9%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDL-----PAGATAQDW- 652 WLVT G A A++ P+ A R + EHP +DL P A+D Sbjct: 1962 WLVTRGAVAVGASERVTRPLQAMTWGLGRVVALEHPERWGGLVDLGEESAPDANGARDAN 2021 Query: 653 AHPIVAAL--HTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHV-LIIGGTGNLGL 709 H +A L +E +LA R Y +R+ P L+ GGTG LG Sbjct: 2022 VHDRLANLVARRDDEDQLALRAAGTYVRRLVRAPHDGARPPAFAPRGAALVTGGTGALGA 2081 Query: 710 EFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQ 769 A GA I L SR G +A A LA+ SA A++ + CDV D AV+ L Sbjct: 2082 HVARWLARIGAEHIVLASRRGAAAPGAAALAEELSALGARVTLAACDVADREAVAALVRD 2141 Query: 770 HRSTPADL--IIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 + A + + HA A + + ++ +A+ AK G + D F + VL Sbjct: 2142 VEAGGATVRAVFHAGGAMHEAPVAAMRVEELADAIAAKARGAQHLHDVFAQRPLDAFVLF 2201 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAA 887 SS GG Q YAAAN LDA+A RA+GL S+ WG W L + +L Sbjct: 2202 SSGAGVWGGGRQGAYAAANAFLDALAEARRADGLAATSIAWGAWAGGGMLATDAERRLKH 2261 Query: 888 IGVIPMPP---AEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVS--- 941 GV PM P A+A + VA D+ R P + PL+ EL S Sbjct: 2262 RGVAPMDPELAVAALAHALDHAETCLAVADVDWARFAPSFASARPRPLLDELAEARSALD 2321 Query: 942 ---------ETAAPAEPAD-LPGRLSNXXXXXXXXXXXXXXDTSVPMVA----------- 980 TAA EPA L L+ T V Sbjct: 2322 ALREPPDDARTAAGPEPASTLRTTLAALPEGERHRHLLALVRTETAAVLGHADASRVEPN 2381 Query: 981 -----LGLDSLQALELRRRVK 996 LGLDSL ++ELRRRV+ Sbjct: 2382 RGFFDLGLDSLMSVELRRRVQ 2402 Score = 115 bits (287), Expect = 4e-23 Identities = 99/329 (30%), Positives = 141/329 (42%), Gaps = 33/329 (10%) Query: 698 VLIIGGTGNLGLEFCDHFAHR-GARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCD 756 VL+ GGTG LG H R G R + L SR G +A A+ L + A A +A+ CD Sbjct: 516 VLVTGGTGTLGALVARHLVQRHGVRSLVLSSRRGPAAPGADDLRRELEAAGASVAIVACD 575 Query: 757 VGDPAAVSRLAAQ-HRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDA 815 GD A+ RL A P ++HAA + +T + + + AKV + + Sbjct: 576 AGDRLALERLLAGIPADRPLTAVVHAAGTLDDGVLTSLTPERLRSVMSAKVDAAAHLDEL 635 Query: 816 FPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHF 875 D VL +S +G GQ YAAAN LDA+AH+ R+ GL VS+ WG W Sbjct: 636 TRPLDLSAFVLFASLSGVLGSPGQANYAAANTFLDALAHQRRSRGLPAVSLDWGYWAERT 695 Query: 876 DLDA----SSMAQLAAIGVIPMPPAEAIALGMQRLGR-NAIVAAFDFDRARPVLETFGYG 930 L A + + ++A G+ P+ + +AL L +A + A FD L Sbjct: 696 GLTAHLGDTDLQRMARGGLRPLTTDDGLALFDAALAHVDAALVAAPFDPV--ALRAHAVA 753 Query: 931 PLVSELL------SPVSETAAPAEPADLPGRLSN----------------XXXXXXXXXX 968 P++ L+ ++ AA A P L RL+ Sbjct: 754 PILRGLVRAGAARRKLANNAASAAP--LAQRLAGLAPKERERAMIDVVRPEIGVVLGLPP 811 Query: 969 XXXXDTSVPMVALGLDSLQALELRRRVKA 997 D P+ LGLDSL A+ELR R+ A Sbjct: 812 SRHLDGDRPLKELGLDSLMAVELRNRLAA 840 >tr|A4F5C6|A4F5C6_SORCE Tax_Id=56 (spiG)SubName: Full=Polyketide synthase;[Sorangium cellulosum] Length = 5331 Score = 166 bits (420), Expect = 2e-38 Identities = 129/456 (28%), Positives = 197/456 (43%), Gaps = 26/456 (5%) Query: 13 IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAEL 72 +PVLLSA + L ++A L H+A H D+ ++A L RA L Sbjct: 4150 VPVLLSAKSDAALRAQAGKLHAHLAEHEDVALVDVAASLATTRSHFERRAAVVADDRAAL 4209 Query: 73 IDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRC 132 + AL A+ + + + A ++ +VF S PAFRAE++ C Sbjct: 4210 LSALAALAEGRAGAGTVAGE-ALPPGKVAFVFPGQGSQWPSMARALLASSPAFRAEIEAC 4268 Query: 133 AQAFEAQSCGSPRNYLLDKNFQDDGSAG-------IVQPALFTQMAALAAMWRSFGIAPN 185 +A S LL D+ A +VQP LF M ALAA WR+ G+ P+ Sbjct: 4269 ERALAPHVDWS----LLAVLGGDEAHAAPMLERVDVVQPVLFAVMIALAATWRAAGVTPD 4324 Query: 186 VTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLA 245 +GHSQGE+AAAYV+G ++LEDA RV+ +R + E LA Sbjct: 4325 AVVGHSQGEIAAAYVAGALSLEDAARVVALRSRAITKLAGRGAMAAVELTTAD-LEARLA 4383 Query: 246 RCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADK 305 G ++ +NSP +SG+ + + +V L+ FAR +RV Y +H++ + Sbjct: 4384 PFGGRLAIAAINSPHAALVSGDPDAIDELVAELSGAQLFARKVRVDYASHSAHVEAIERT 4443 Query: 306 LRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQR 365 L A+ P+ + A G + E +W+ NLR+ VRF+ A A + Sbjct: 4444 LLEALDGIAPRPA----TVPLYSAVTGERLDGEALGAAHWYRNLRHTVRFEHATRALLDD 4499 Query: 366 DVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVH 425 FVE++ HP L +A+ + + +A A+ + R DL F +LA+L Sbjct: 4500 GHRFFVEVSPHPVLTVALRDTI-----DASGHDAVACASLRRDEGDLARFNLSLAELHTR 4554 Query: 426 DLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L W A P + + L P R WL Sbjct: 4555 GLAVDWRAFFA-PFAPRTVAL---PTYAFQRERFWL 4586 Score = 149 bits (377), Expect = 2e-33 Identities = 130/469 (27%), Positives = 196/469 (41%), Gaps = 31/469 (6%) Query: 2 SAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXX 61 +A A P +P +LSA T L ++A L HVAA+ +L+ + L Sbjct: 2037 AATAEAAPGRELPFVLSAKTEAALRAQARRLHAHVAANGELSLADLGFSLATTRSHFDER 2096 Query: 62 XXXXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYES 121 R L+ L A+ P + + + + +VF +S Sbjct: 2097 AAVVASDRDALLHGLDALARGEPAPETVAASTVSSGKLV-FVFPGQGSQWPEMASALLDS 2155 Query: 122 VPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAM 176 P FR ++ C A S L DG A +VQP LF M ALAAM Sbjct: 2156 EPVFREQLLACEGALAPHVDWSLLTVLRHGR---DGDASLDRVDVVQPVLFAVMVALAAM 2212 Query: 177 WRSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXD 236 WR+ G+ P+ +GHSQGE+AAAYV+G ++LEDA +V+ +R Sbjct: 2213 WRATGVEPDAVVGHSQGEIAAAYVAGALSLEDAAKVVALRARAITRLAGRGAMAAIELPA 2272 Query: 237 RETCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHT 296 E + L G ++ +NSPR ++G+ V +V TL+ FAR +RV Y +H+ Sbjct: 2273 SE-LDRHLDGLDGRIGIAAINSPRTTLVAGDVAAVDALVGTLSAAQIFARKVRVDYASHS 2331 Query: 297 SLIHDGADKLRAAIQDQLQHP----SFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNI 352 + AAI+++L S + + A G + + +W+ NLR Sbjct: 2332 EHV--------AAIENELLRDLGGISPRASALPIYSAVTGEKLDGQALDAAHWYRNLRQT 2383 Query: 353 VRFDKAIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDL 412 VRF+ A A + FVE++ HP L LA+ E + B+A A VV T R Sbjct: 2384 VRFEDATRALLADQHRFFVEVSPHPVLSLALRETI----BDA-GLSAAVVPTLRRDDGHR 2438 Query: 413 GEFTRNLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 F +LA+L W L + + +PL P R WL Sbjct: 2439 ARFLLSLAELHARGHRVVWSAL-FDAHRPRRVPL---PTYAFQRERFWL 2483 Score = 142 bits (357), Expect = 3e-31 Identities = 129/431 (29%), Positives = 173/431 (40%), Gaps = 33/431 (7%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPA-----GATAQDWA 653 WL + G + + AD +P AA R + EHP +DL + GA Sbjct: 1119 WLFSRGAVSVSRADAIVNPAQAATWGLARVVSLEHPERLGGAVDLASSLGASGALDAAAI 1178 Query: 654 HPIVAALH--TANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNLGLEF 711 +VAAL A E ELA R +A+R+ VL+ GGTG LG Sbjct: 1179 DHLVAALGGALAGEDELALRPEGLFARRLVRAPLGEAPRPRAPRGTVLVTGGTGALGAHV 1238 Query: 712 CDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRL-AAQH 770 FA RGA+ + L SR G A A L +A A++ + CDVGD AA+ L AA Sbjct: 1239 ARLFAQRGAKHLVLTSRRGPDAPSARALHDELTALGARVTIAACDVGDRAALEELFAAMP 1298 Query: 771 RSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSA 830 P ++HAA +T + D AK + + + D VL SSA Sbjct: 1299 ADAPLSAVVHAAGVLDDGVLDALTPERLDAVFRAKALAARHLDELTRSRDLDAFVLFSSA 1358 Query: 831 RATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGV 890 G GQ YAAAN LDA+A RA G+ S+ WG W L+ + + L G+ Sbjct: 1359 SGVFGSAGQGSYAAANAYLDALAEARRARGVTATSIAWGAWAGGGMLEDAVASDLRRSGL 1418 Query: 891 IPMPPAEAIALGMQRLGRN---AIVAAFDFDRARPVLETFGYGPLVSEL----LSPVSET 943 PM P A A L + +A D+ R P + P VSEL + + Sbjct: 1419 SPMRPEVATAALAHALDHDDDVVTIADIDWARFAPSFASVRERPFVSELPEAKRAQGALA 1478 Query: 944 AAPAEPAD------------------LPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDS 985 A PA P + L G + D LGLDS Sbjct: 1479 ANPARPDESALLTALRAQSDDDRLRHLVGLVLGETAAVLGHADASRVDAHKGFFDLGLDS 1538 Query: 986 LQALELRRRVK 996 L A+ELR R++ Sbjct: 1539 LMAVELRLRLQ 1549 Score = 127 bits (320), Expect = 6e-27 Identities = 132/441 (29%), Positives = 175/441 (39%), Gaps = 43/441 (9%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDL-----PAGATAQDW- 652 WLVT G A A++ P+ A R + EHP +DL P A+D Sbjct: 4775 WLVTRGAVAVGASERVTRPLQAMTWGLGRVVALEHPERWGGLVDLGEESAPDANGARDAN 4834 Query: 653 AHPIVAAL--HTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHV-LIIGGTGNLGL 709 H +A L +E +LA R Y +R+ P L+ GGTG LG Sbjct: 4835 VHDRLANLVARRDDEDQLALRAAGTYVRRLVRAPHDGARPPAFAPRGAALVTGGTGALGA 4894 Query: 710 EFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQ 769 A GA I L SR G +A A LA+ SA A++ + CDV D AV+ L Sbjct: 4895 HVARWLARIGAEHIVLASRRGAAAPGAAALAEELSALGARVTLAACDVADREAVAALVRD 4954 Query: 770 HRSTPADL--IIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLC 827 + A + + HA A + + ++ +A+ AK G + D F + VL Sbjct: 4955 VEAGGATVRAVFHAGGAMHEAPVAAMRVEELADAIAAKARGAQHLHDVFAQRPLDAFVLF 5014 Query: 828 SSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAA 887 SS GG Q YAAAN LDA+A RA+GL S+ WG W L + +L Sbjct: 5015 SSGAGVWGGGRQGAYAAANAFLDALAEARRADGLAATSIAWGAWAGGGMLATDAERRLKH 5074 Query: 888 IGVIPMPP---AEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVS--- 941 GV PM P A+A + VA D+ R P + PL+ EL S Sbjct: 5075 RGVAPMDPELAVAALAHALDHAETCLAVADVDWARFAPSFASARPRPLLDELAEARSALD 5134 Query: 942 ---------ETAAPAEPAD-LPGRLSNXXXXXXXXXXXXXXDTSVPMVA----------- 980 TAA EPA L L+ T V Sbjct: 5135 ALREPPDDARTAAGPEPASTLRTTLAALPEGERHRHLLALVRTETAAVLGHADASRVEPN 5194 Query: 981 -----LGLDSLQALELRRRVK 996 LGLDSL ++ELRRRV+ Sbjct: 5195 RGFFDLGLDSLMSVELRRRVQ 5215 Score = 115 bits (287), Expect = 4e-23 Identities = 99/329 (30%), Positives = 141/329 (42%), Gaps = 33/329 (10%) Query: 698 VLIIGGTGNLGLEFCDHFAHR-GARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCD 756 VL+ GGTG LG H R G R + L SR G +A A+ L + A A +A+ CD Sbjct: 3329 VLVTGGTGTLGALVARHLVQRHGVRSLVLSSRRGPAAPGADDLRRELEAAGASVAIVACD 3388 Query: 757 VGDPAAVSRLAAQ-HRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDA 815 GD A+ RL A P ++HAA + +T + + + AKV + + Sbjct: 3389 AGDRLALERLLAGIPADRPLTAVVHAAGTLDDGVLTSLTPERLRSVMSAKVDAAAHLDEL 3448 Query: 816 FPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHF 875 D VL +S +G GQ YAAAN LDA+AH+ R+ GL VS+ WG W Sbjct: 3449 TRPLDLSAFVLFASLSGVLGSPGQANYAAANTFLDALAHQRRSRGLPAVSLDWGYWAERT 3508 Query: 876 DLDA----SSMAQLAAIGVIPMPPAEAIALGMQRLGR-NAIVAAFDFDRARPVLETFGYG 930 L A + + ++A G+ P+ + +AL L +A + A FD L Sbjct: 3509 GLTAHLGDTDLQRMARGGLRPLTTDDGLALFDAALAHVDAALVAAPFDPV--ALRAHAVA 3566 Query: 931 PLVSELL------SPVSETAAPAEPADLPGRLSN----------------XXXXXXXXXX 968 P++ L+ ++ AA A P L RL+ Sbjct: 3567 PILRGLVRAGAARRKLANNAASAAP--LAQRLAGLAPKERERAMIDVVRPEIGVVLGLPP 3624 Query: 969 XXXXDTSVPMVALGLDSLQALELRRRVKA 997 D P+ LGLDSL A+ELR R+ A Sbjct: 3625 SRHLDGDRPLKELGLDSLMAVELRNRLAA 3653 Score = 105 bits (263), Expect = 2e-20 Identities = 114/462 (24%), Positives = 176/462 (38%), Gaps = 28/462 (6%) Query: 13 IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAEL 72 +PV++SA T L +A L H+AA P+L I+A L R + Sbjct: 481 LPVVISAKTEGALRGQAARLHAHLAARPELALADIAASLATTRSHFEHRAVVVAHDREAV 540 Query: 73 IDALQAMID--RYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVD 130 + AL + P A + R+ +F Y++ P FR +D Sbjct: 541 LTALDGLARGANASPPPGTLVGGDAPKGRLAILFTGQGGQRAAMGHGLYQAFPVFRDALD 600 Query: 131 RCAQAFEAQSCGSPRNYLLDKNFQDDGS--AGIVQPALFTQMAALA---AMWR---SFGI 182 + R L F GS A ++ +FTQ A A A++R ++G+ Sbjct: 601 AVCAHLDRDLDRPLREVL----FAPKGSELARLLDETVFTQTALFALEVALFRLVEAWGV 656 Query: 183 APNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIR-XXXXXXXXXXXXXXXXXXXDRETCE 241 AP+ +GHS GE+ AA+V+G ++LEDA ++ R + E Sbjct: 657 APDALLGHSVGEITAAHVAGVLSLEDACALVSARARLMQALPARDAAMVAIAASEGEVAA 716 Query: 242 DLLARCSGWAQ--LSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLI 299 + AR G A+ ++ +N P ++G+R+ V + G +RV + H+ + Sbjct: 717 VIAARGEGGARATIAAINGPSSTVVAGDRDAVLDVAARFEALGRKTSRLRVSHAFHSHHM 776 Query: 300 HDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAI 359 D R + HP + + G G EL DYW + R+ VRF + Sbjct: 777 DGMLDAFRRVAEGLTFHPPRIPIVSNVTGQRAG---DGELCSADYWVRHARSAVRFADGL 833 Query: 360 AAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNL 419 V TF+EL H L +AL +A R A+ V T D L Sbjct: 834 GTLHTERVSTFLELGPHGVLSAL---GQSALEADAPSR-ALFVPTLRADRDDGDALVTAL 889 Query: 420 AQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L W A P GA+ +PL P R W+ Sbjct: 890 GALHARGHRVDWRAFFA-PVGARRVPL---PTYAFQRERFWV 927 >tr|Q8GBX6|Q8GBX6_SORCE Tax_Id=56 (spiH)SubName: Full=Polyketide synthase;[Sorangium cellulosum] Length = 5017 Score = 166 bits (419), Expect = 2e-38 Identities = 137/460 (29%), Positives = 195/460 (42%), Gaps = 19/460 (4%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 AA LP +PVLLS T E L ++A L H+A PD I+A L Sbjct: 473 AAPALP--AVPVLLSGKTDEALRAQAARLHAHLAGRPDARLVDIAASLATTRTHFDRRAA 530 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL+ AL A+ P + A R+ +VF S Sbjct: 531 VVAADRDELLGALDALARGEAGPGSVVAS-AIPAGRVVFVFPGQGSQWVGMARALLASSV 589 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDD--GSAGIVQPALFTQMAALAAMWRSFG 181 FR E+ C +A S L + G +VQP LF M ALAA+WRS G Sbjct: 590 VFRDEIAACERALAPHVAWSLGAVLRGDGDEATLLGRVDVVQPVLFAVMVALAALWRSIG 649 Query: 182 IAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCE 241 + P+ +GHSQGE+AAAYV+G ++LEDA +V+ +R R+T E Sbjct: 650 VTPDAVVGHSQGEIAAAYVAGALSLEDAAKVVALRARALTKIAGRGAMAAVELGARDT-E 708 Query: 242 DLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHD 301 LA ++ +NSPR ++G+ + + +V L FAR +RV Y +H++ + Sbjct: 709 ARLAPFGDAIAIAAINSPRATLVAGDTDAIDALVRDLEAAQIFARKVRVDYASHSAHVEA 768 Query: 302 GADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAA 361 +L A + V A GA + +WF NLR+ VRF+ A A Sbjct: 769 IERELLADLAGIEPRAGAV----PLYSAVTGAKLDGSRLDAAHWFRNLRSTVRFEDATRA 824 Query: 362 AVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQ 421 FVE++ HP L LA+ E L+++ + A VV + R DL F + + Sbjct: 825 LHDDGHRFFVEVSPHPVLALALDETLSSIGGD-----AAVVSSLRRDEGDLERFLLSAGE 879 Query: 422 LAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L W A P GA+ + L P R WL Sbjct: 880 LHARGHAIDWGAFFA-PLGARRVTL---PTYAFQRERFWL 915 Score = 131 bits (330), Expect = 4e-28 Identities = 126/433 (29%), Positives = 171/433 (39%), Gaps = 38/433 (8%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPA----GATAQDWAH 654 W+VT G A +D PV A A R + E P +DLP GA Sbjct: 1108 WIVTRGAVAIGRSDRIESPVQAMAWGLGRVVSLEQPERWGGLVDLPRAHADGALDATAIE 1167 Query: 655 PIVAALHTAN-EPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH-VLIIGGTGNLGLEFC 712 +VAAL + E ELA R +A+R+ P VL+ GGTG LG Sbjct: 1168 RLVAALGSREGEDELALRPTGLFARRLARAPLGDAPAQRFEPRGTVLVTGGTGALGAHVA 1227 Query: 713 DHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRL-AAQHR 771 A GA + L SR G +A AE L + A++ + CDV D AA+ L AA Sbjct: 1228 RWLARHGAAHLVLASRRGAAAPGAEALRAELTELGARVTIAACDVADRAAIEELFAALPA 1287 Query: 772 STPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSAR 831 P I H A +T + + L+ K + + D VL SSA Sbjct: 1288 EEPLTAIFHTAGVIDDGVLGSLTPERLETVLHGKADAARTLHELTKTRDLAAFVLFSSAA 1347 Query: 832 ATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLAA 887 G GQ YAAAN LDA+A RA GL SV WG W + FD+ A + + Sbjct: 1348 GVFGNAGQASYAAANAFLDALAEERRALGLRATSVAWGAWAGAGMLTFDV-AQGLRRGGF 1406 Query: 888 IGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPA 947 + P A+A + R + +A+ D+ R P + PLV++L P + A A Sbjct: 1407 AAMEPEIAVAALASALDRDETHVTIASIDWARFAPSYASARQRPLVADL--PDARRALDA 1464 Query: 948 EPA------------------------DLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGL 983 +P+ L + D LGL Sbjct: 1465 QPSASTEHDETALVATLRALSGEARLRHLVSLVLAQTAAVLGHADRSRLDPQRGFFDLGL 1524 Query: 984 DSLQALELRRRVK 996 DSL A+ELRRR++ Sbjct: 1525 DSLMAVELRRRLQ 1537 Score = 124 bits (310), Expect = 9e-26 Identities = 123/443 (27%), Positives = 172/443 (38%), Gaps = 38/443 (8%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVA 658 WLVT G + +D + R +G EHP +D+ G T A + Sbjct: 2663 WLVTRGAVSTGRSDRLASAAQSMTWGLGRVVGLEHPERWGGLVDVADGDTIDARALDRLV 2722 Query: 659 ALHTAN--EPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLEFCDH 714 L + E +LA R +A+R+ L+ GGTG LG Sbjct: 2723 TLLASRDGEDQLALRPTGIFARRLVRAPLGDAPPARTYTARGTSLVTGGTGALGAHVARF 2782 Query: 715 FAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQ--HRS 772 A RGA + LVSR GE A A L A A++ + CDV D A+V+ L A+ + Sbjct: 2783 LAGRGAEHLVLVSRRGEDAPGAGALRAELEALGARVTLAACDVADRASVAALLARLDAQG 2842 Query: 773 TPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARA 832 P ++HA A + D + AKV G + + + VL +S Sbjct: 2843 DPVRAVVHAGGVVAQAALASTDLDGVQAVVAAKVRGALHLHELLGDRELDAFVLFASGAG 2902 Query: 833 TIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLAAI 888 G Q YAA N LDA+A RA GL S+ WG W + DA + +L Sbjct: 2903 VWGSGQQGAYAAGNAFLDALAEVRRAAGLTATSIAWGAWAGGGMLADHADADAEVELRKR 2962 Query: 889 GVIPMPPAEAIA--LGMQRLGRNAI-VAAFDFDRARPVLETFGYGPLVSELLSPVSETAA 945 G++PM PA AIA G G A+ VA+ D+ R P + PL+ +L A Sbjct: 2963 GLVPMAPALAIAALAGALDHGETAVTVASVDWARFAPAFASARPRPLLLDLPEAQRAIEA 3022 Query: 946 PAEPADLPGRLSN-------------------------XXXXXXXXXXXXXXDTSVPMVA 980 P+ PA G ++ D Sbjct: 3023 PSAPAGADGASADRALVEALRPLSEADRARHLVELVVAETAAVLGHADASAIDPHKGFFD 3082 Query: 981 LGLDSLQALELRRRVKAEFDHEL 1003 LGLDSL A+EL R+++A EL Sbjct: 3083 LGLDSLVAVELLRKLRARTGVEL 3105 Score = 111 bits (278), Expect = 5e-22 Identities = 113/464 (24%), Positives = 174/464 (37%), Gaps = 20/464 (4%) Query: 3 AAAYRLP-DGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXX 61 AA LP G +P +LSA + L ++A ALRD +A PD ++A L Sbjct: 2023 AARGALPLSGALPFVLSAKSDAALRAQAAALRDQLARTPDAALVDVAAALATTRSQFDHR 2082 Query: 62 XXXXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYES 121 L+ AL+ + P AA ++ ++F Y++ Sbjct: 2083 AAIAASDHGALVAALEGLAAGVAAPGTFVAKGAA--DKLAFLFTGQGAQRAAMGRGLYDA 2140 Query: 122 VPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGS----AGIVQPALFTQMAALAAMW 177 P FR +D A + + R+ L + S QPALF AL + Sbjct: 2141 FPVFRDALDAVASHLDRELDRPLRDVLFAPKGSELASLLDRTEFTQPALFALEVALFRLV 2200 Query: 178 RSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDR 237 ++G+ P+V +GHS GE+AAA+V+G ++L DA ++ R Sbjct: 2201 EAWGVTPDVLLGHSVGELAAAHVAGVLSLADACTLVAARARLMQALPARDGAMVTVHATE 2260 Query: 238 ETCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTS 297 L G A+++ +N+P I+G+ + V + G A +RV + H+ Sbjct: 2261 AEVLAALEGRDGRAEIAAINAPSSTVIAGDVDAVLRVAAHFEARGRKATRLRVSHAFHSH 2320 Query: 298 LIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDK 357 + D R + HP I + G E+ DYW ++R+ VRF Sbjct: 2321 HMDPMLDAFRRVAEGLTFHP----PRIPIVSNVTGRLAADEIRSPDYWVRHVRSAVRFAD 2376 Query: 358 AIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTR 417 I V +F EL H L LA + E PA+ G + D+ T Sbjct: 2377 GINTLEADGVSSFFELGPHGVLSALGESALANAQREVAFVPALRDGRA-----DVDALTA 2431 Query: 418 NLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L+ L V W P Q + L P R WL Sbjct: 2432 ALSSLHVRGHRVDWAAFFG-PFDPQTVAL---PTYAFQRDRFWL 2471 Score = 111 bits (278), Expect = 5e-22 Identities = 132/446 (29%), Positives = 180/446 (40%), Gaps = 57/446 (12%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAG-ATAQDWAHPIVA 658 L+T A A + D AA RS AE+ +DL A+ + + + Sbjct: 4470 LLTQRAVATCAGEDVLDLASAALWGLVRSAQAENRDRAILLVDLDGSDASRRALPYAVGG 4529 Query: 659 ALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXC-----------PEH-VLIIGGTGN 706 AL A EP+LA RDG A R+ PE VL+ GGTG Sbjct: 4530 ALDDA-EPQLALRDGRRLAPRLARVAAPTAATANAATSTSATPRALDPEGTVLVTGGTGT 4588 Query: 707 LGLEFCDHFAHR-GARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR 765 LG R G + + L+SR G A A LA A A + + D +PAA++R Sbjct: 4589 LGALVARRLVERHGVKHLVLLSRRGPDAPGATDLAAELQARGASVVLAAADAAEPAALAR 4648 Query: 766 -LAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRI 824 L A P ++HAA S +T L AKV + + + Sbjct: 4649 VLLAIPHDRPLTAVVHAAGTLDDGVLSSMTPARLSAVLRAKVDAAVNLDEQTRHSPLRAF 4708 Query: 825 VLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW------TVHFDLD 878 VL SS +G Q YAAAN LDA+AHR A GL V++ WG W T H L+ Sbjct: 4709 VLFSSLSGVLGSPAQSNYAAANAFLDALAHRRAARGLPAVALDWGYWAQTSGLTKH--LE 4766 Query: 879 ASSMAQLAAIGVIPMPPAEAIALGMQRLGRNA---IVAAFDFDRARPVLETFGYGPLVSE 935 + + ++A G+ P+ EA+AL L ++A + AAFD D R G +S Sbjct: 4767 QADLRRIARGGLRPLASDEALALFDLALAQDAPCLVPAAFDADALRK------SGDALSA 4820 Query: 936 LL-SPVSETAAPAEPADLPG-------RLSNXXXXXXXXXXXXXXDTSV----------- 976 LL V+ A A+ A G RL++ V Sbjct: 4821 LLRGLVAGPRARAQRASGAGAASALKLRLASLAPLERHRMLLDVVRADVATVLGVASPLD 4880 Query: 977 -----PMVALGLDSLQALELRRRVKA 997 P+ LGLDSL A+ELR R+ A Sbjct: 4881 IEPGRPLQELGLDSLMAIELRNRLAA 4906 Score = 95.9 bits (237), Expect = 3e-17 Identities = 101/417 (24%), Positives = 156/417 (37%), Gaps = 36/417 (8%) Query: 3 AAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXX 62 AAA P +PV+LSA + L ++A LR HV P ++A L Sbjct: 3585 AAATDEPPPAVPVVLSAKSERALRAQAERLRAHVTGRPGDALVDVAASLATTRSHFEHRA 3644 Query: 63 XXXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESV 122 L DAL + + + + ++ +F Y + Sbjct: 3645 AIVARDLGALEDALAGLAEGRSPAGTVVSRTTG--GKLALLFTGQGGQRAAMGRGLYGAF 3702 Query: 123 PAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGS--AGIVQPALFTQMA------ALA 174 FR D + + + L D F GS A ++ L+TQ + AL Sbjct: 3703 SVFRDAFDAACSYLDREL----EHPLRDVVFAPRGSELAALLDETLYTQTSLFALEVALF 3758 Query: 175 AMWRSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXX 234 + ++G+ P+V +GHS GE+ AA+V+G ++LEDA ++ R Sbjct: 3759 RLVEAWGVTPHVLLGHSIGELVAAHVAGVLSLEDACTLVAARARLMHALPRRDAAMVAV- 3817 Query: 235 XDRETCE-------DLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARV 287 CE D +A G A ++ VN+P ++G+RE V + G Sbjct: 3818 ---HACESEVLDALDAMAGLDGRASIAAVNAPSSTVVAGDREAVLAVAARFEALGRKTSR 3874 Query: 288 IRVRYPAHTSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFW 347 +RV + H+ + + R + P + + GA +L DYW Sbjct: 3875 LRVSHAFHSHHLDPMLEAFRRVAEGVRFEPPRIPIVSNVTGARAS---NDDLCSADYWVR 3931 Query: 348 NLRNIVRFDKAIAAAVQRDVETFVELAEHPTLQLAIHEN--------LAALRDEADD 396 + R VRF + A V TF+EL H L HE L ALRD DD Sbjct: 3932 HARGTVRFADGLEALRADGVSTFLELGPHAVLCALGHETLESEAVAFLPALRDGRDD 3988 >tr|A4F5C7|A4F5C7_SORCE Tax_Id=56 (spiH)SubName: Full=Polyketide synthase;[Sorangium cellulosum] Length = 5005 Score = 166 bits (419), Expect = 2e-38 Identities = 137/460 (29%), Positives = 195/460 (42%), Gaps = 19/460 (4%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 AA LP +PVLLS T E L ++A L H+A PD I+A L Sbjct: 461 AAPALP--AVPVLLSGKTDEALRAQAARLHAHLAGRPDARLVDIAASLATTRTHFDRRAA 518 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 R EL+ AL A+ P + A R+ +VF S Sbjct: 519 VVAADRDELLGALDALARGEAGPGSVVAS-AIPAGRVVFVFPGQGSQWVGMARALLASSV 577 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDD--GSAGIVQPALFTQMAALAAMWRSFG 181 FR E+ C +A S L + G +VQP LF M ALAA+WRS G Sbjct: 578 VFRDEIAACERALAPHVAWSLGAVLRGDGDEATLLGRVDVVQPVLFAVMVALAALWRSIG 637 Query: 182 IAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCE 241 + P+ +GHSQGE+AAAYV+G ++LEDA +V+ +R R+T E Sbjct: 638 VTPDAVVGHSQGEIAAAYVAGALSLEDAAKVVALRARALTKIAGRGAMAAVELGARDT-E 696 Query: 242 DLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHD 301 LA ++ +NSPR ++G+ + + +V L FAR +RV Y +H++ + Sbjct: 697 ARLAPFGDAIAIAAINSPRATLVAGDTDAIDALVRDLEAAQIFARKVRVDYASHSAHVEA 756 Query: 302 GADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAA 361 +L A + V A GA + +WF NLR+ VRF+ A A Sbjct: 757 IERELLADLAGIEPRAGAV----PLYSAVTGAKLDGSRLDAAHWFRNLRSTVRFEDATRA 812 Query: 362 AVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQ 421 FVE++ HP L LA+ E L+++ + A VV + R DL F + + Sbjct: 813 LHDDGHRFFVEVSPHPVLALALDETLSSIGGD-----AAVVSSLRRDEGDLERFLLSAGE 867 Query: 422 LAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L W A P GA+ + L P R WL Sbjct: 868 LHARGHAIDWGAFFA-PLGARRVTL---PTYAFQRERFWL 903 Score = 131 bits (330), Expect = 4e-28 Identities = 126/433 (29%), Positives = 171/433 (39%), Gaps = 38/433 (8%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPA----GATAQDWAH 654 W+VT G A +D PV A A R + E P +DLP GA Sbjct: 1096 WIVTRGAVAIGRSDRIESPVQAMAWGLGRVVSLEQPERWGGLVDLPRAHADGALDATAIE 1155 Query: 655 PIVAALHTAN-EPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH-VLIIGGTGNLGLEFC 712 +VAAL + E ELA R +A+R+ P VL+ GGTG LG Sbjct: 1156 RLVAALGSREGEDELALRPTGLFARRLARAPLGDAPAQRFEPRGTVLVTGGTGALGAHVA 1215 Query: 713 DHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRL-AAQHR 771 A GA + L SR G +A AE L + A++ + CDV D AA+ L AA Sbjct: 1216 RWLARHGAAHLVLASRRGAAAPGAEALRAELTELGARVTIAACDVADRAAIEELFAALPA 1275 Query: 772 STPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSAR 831 P I H A +T + + L+ K + + D VL SSA Sbjct: 1276 EEPLTAIFHTAGVIDDGVLGSLTPERLETVLHGKADAARTLHELTKTRDLAAFVLFSSAA 1335 Query: 832 ATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLAA 887 G GQ YAAAN LDA+A RA GL SV WG W + FD+ A + + Sbjct: 1336 GVFGNAGQASYAAANAFLDALAEERRALGLRATSVAWGAWAGAGMLTFDV-AQGLRRGGF 1394 Query: 888 IGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPA 947 + P A+A + R + +A+ D+ R P + PLV++L P + A A Sbjct: 1395 AAMEPEIAVAALASALDRDETHVTIASIDWARFAPSYASARQRPLVADL--PDARRALDA 1452 Query: 948 EPA------------------------DLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGL 983 +P+ L + D LGL Sbjct: 1453 QPSASTEHDETALVATLRALSGEARLRHLVSLVLAQTAAVLGHADRSRLDPQRGFFDLGL 1512 Query: 984 DSLQALELRRRVK 996 DSL A+ELRRR++ Sbjct: 1513 DSLMAVELRRRLQ 1525 Score = 124 bits (310), Expect = 9e-26 Identities = 123/443 (27%), Positives = 172/443 (38%), Gaps = 38/443 (8%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVA 658 WLVT G + +D + R +G EHP +D+ G T A + Sbjct: 2651 WLVTRGAVSTGRSDRLASAAQSMTWGLGRVVGLEHPERWGGLVDVADGDTIDARALDRLV 2710 Query: 659 ALHTAN--EPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLEFCDH 714 L + E +LA R +A+R+ L+ GGTG LG Sbjct: 2711 TLLASRDGEDQLALRPTGIFARRLVRAPLGDAPPARTYTARGTSLVTGGTGALGAHVARF 2770 Query: 715 FAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQ--HRS 772 A RGA + LVSR GE A A L A A++ + CDV D A+V+ L A+ + Sbjct: 2771 LAGRGAEHLVLVSRRGEDAPGAGALRAELEALGARVTLAACDVADRASVAALLARLDAQG 2830 Query: 773 TPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARA 832 P ++HA A + D + AKV G + + + VL +S Sbjct: 2831 DPVRAVVHAGGVVAQAALASTDLDGVQAVVAAKVRGALHLHELLGDRELDAFVLFASGAG 2890 Query: 833 TIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLAAI 888 G Q YAA N LDA+A RA GL S+ WG W + DA + +L Sbjct: 2891 VWGSGQQGAYAAGNAFLDALAEVRRAAGLTATSIAWGAWAGGGMLADHADADAEVELRKR 2950 Query: 889 GVIPMPPAEAIA--LGMQRLGRNAI-VAAFDFDRARPVLETFGYGPLVSELLSPVSETAA 945 G++PM PA AIA G G A+ VA+ D+ R P + PL+ +L A Sbjct: 2951 GLVPMAPALAIAALAGALDHGETAVTVASVDWARFAPAFASARPRPLLLDLPEAQRAIEA 3010 Query: 946 PAEPADLPGRLSN-------------------------XXXXXXXXXXXXXXDTSVPMVA 980 P+ PA G ++ D Sbjct: 3011 PSAPAGADGASADRALVEALRPLSEADRARHLVELVVAETAAVLGHADASAIDPHKGFFD 3070 Query: 981 LGLDSLQALELRRRVKAEFDHEL 1003 LGLDSL A+EL R+++A EL Sbjct: 3071 LGLDSLVAVELLRKLRARTGVEL 3093 Score = 111 bits (278), Expect = 5e-22 Identities = 113/464 (24%), Positives = 174/464 (37%), Gaps = 20/464 (4%) Query: 3 AAAYRLP-DGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXX 61 AA LP G +P +LSA + L ++A ALRD +A PD ++A L Sbjct: 2011 AARGALPLSGALPFVLSAKSDAALRAQAAALRDQLARTPDAALVDVAAALATTRSQFDHR 2070 Query: 62 XXXXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYES 121 L+ AL+ + P AA ++ ++F Y++ Sbjct: 2071 AAIAASDHGALVAALEGLAAGVAAPGTFVAKGAA--DKLAFLFTGQGAQRAAMGRGLYDA 2128 Query: 122 VPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGS----AGIVQPALFTQMAALAAMW 177 P FR +D A + + R+ L + S QPALF AL + Sbjct: 2129 FPVFRDALDAVASHLDRELDRPLRDVLFAPKGSELASLLDRTEFTQPALFALEVALFRLV 2188 Query: 178 RSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDR 237 ++G+ P+V +GHS GE+AAA+V+G ++L DA ++ R Sbjct: 2189 EAWGVTPDVLLGHSVGELAAAHVAGVLSLADACTLVAARARLMQALPARDGAMVTVHATE 2248 Query: 238 ETCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTS 297 L G A+++ +N+P I+G+ + V + G A +RV + H+ Sbjct: 2249 AEVLAALEGRDGRAEIAAINAPSSTVIAGDVDAVLRVAAHFEARGRKATRLRVSHAFHSH 2308 Query: 298 LIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDK 357 + D R + HP I + G E+ DYW ++R+ VRF Sbjct: 2309 HMDPMLDAFRRVAEGLTFHP----PRIPIVSNVTGRLAADEIRSPDYWVRHVRSAVRFAD 2364 Query: 358 AIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTR 417 I V +F EL H L LA + E PA+ G + D+ T Sbjct: 2365 GINTLEADGVSSFFELGPHGVLSALGESALANAQREVAFVPALRDGRA-----DVDALTA 2419 Query: 418 NLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L+ L V W P Q + L P R WL Sbjct: 2420 ALSSLHVRGHRVDWAAFFG-PFDPQTVAL---PTYAFQRDRFWL 2459 Score = 111 bits (278), Expect = 5e-22 Identities = 132/446 (29%), Positives = 180/446 (40%), Gaps = 57/446 (12%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAG-ATAQDWAHPIVA 658 L+T A A + D AA RS AE+ +DL A+ + + + Sbjct: 4458 LLTQRAVATCAGEDVLDLASAALWGLVRSAQAENRDRAILLVDLDGSDASRRALPYAVGG 4517 Query: 659 ALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXC-----------PEH-VLIIGGTGN 706 AL A EP+LA RDG A R+ PE VL+ GGTG Sbjct: 4518 ALDDA-EPQLALRDGRRLAPRLARVAAPTAATANAATSTSATPRALDPEGTVLVTGGTGT 4576 Query: 707 LGLEFCDHFAHR-GARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR 765 LG R G + + L+SR G A A LA A A + + D +PAA++R Sbjct: 4577 LGALVARRLVERHGVKHLVLLSRRGPDAPGATDLAAELQARGASVVLAAADAAEPAALAR 4636 Query: 766 -LAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRI 824 L A P ++HAA S +T L AKV + + + Sbjct: 4637 VLLAIPHDRPLTAVVHAAGTLDDGVLSSMTPARLSAVLRAKVDAAVNLDEQTRHSPLRAF 4696 Query: 825 VLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW------TVHFDLD 878 VL SS +G Q YAAAN LDA+AHR A GL V++ WG W T H L+ Sbjct: 4697 VLFSSLSGVLGSPAQSNYAAANAFLDALAHRRAARGLPAVALDWGYWAQTSGLTKH--LE 4754 Query: 879 ASSMAQLAAIGVIPMPPAEAIALGMQRLGRNA---IVAAFDFDRARPVLETFGYGPLVSE 935 + + ++A G+ P+ EA+AL L ++A + AAFD D R G +S Sbjct: 4755 QADLRRIARGGLRPLASDEALALFDLALAQDAPCLVPAAFDADALRK------SGDALSA 4808 Query: 936 LL-SPVSETAAPAEPADLPG-------RLSNXXXXXXXXXXXXXXDTSV----------- 976 LL V+ A A+ A G RL++ V Sbjct: 4809 LLRGLVAGPRARAQRASGAGAASALKLRLASLAPLERHRMLLDVVRADVATVLGVASPLD 4868 Query: 977 -----PMVALGLDSLQALELRRRVKA 997 P+ LGLDSL A+ELR R+ A Sbjct: 4869 IEPGRPLQELGLDSLMAIELRNRLAA 4894 Score = 95.9 bits (237), Expect = 3e-17 Identities = 101/417 (24%), Positives = 156/417 (37%), Gaps = 36/417 (8%) Query: 3 AAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXX 62 AAA P +PV+LSA + L ++A LR HV P ++A L Sbjct: 3573 AAATDEPPPAVPVVLSAKSERALRAQAERLRAHVTGRPGDALVDVAASLATTRSHFEHRA 3632 Query: 63 XXXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESV 122 L DAL + + + + ++ +F Y + Sbjct: 3633 AIVARDLGALEDALAGLAEGRSPAGTVVSRTTG--GKLALLFTGQGGQRAAMGRGLYGAF 3690 Query: 123 PAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGS--AGIVQPALFTQMA------ALA 174 FR D + + + L D F GS A ++ L+TQ + AL Sbjct: 3691 SVFRDAFDAACSYLDREL----EHPLRDVVFAPRGSELAALLDETLYTQTSLFALEVALF 3746 Query: 175 AMWRSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXX 234 + ++G+ P+V +GHS GE+ AA+V+G ++LEDA ++ R Sbjct: 3747 RLVEAWGVTPHVLLGHSIGELVAAHVAGVLSLEDACTLVAARARLMHALPRRDAAMVAV- 3805 Query: 235 XDRETCE-------DLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARV 287 CE D +A G A ++ VN+P ++G+RE V + G Sbjct: 3806 ---HACESEVLDALDAMAGLDGRASIAAVNAPSSTVVAGDREAVLAVAARFEALGRKTSR 3862 Query: 288 IRVRYPAHTSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFW 347 +RV + H+ + + R + P + + GA +L DYW Sbjct: 3863 LRVSHAFHSHHLDPMLEAFRRVAEGVRFEPPRIPIVSNVTGARAS---NDDLCSADYWVR 3919 Query: 348 NLRNIVRFDKAIAAAVQRDVETFVELAEHPTLQLAIHEN--------LAALRDEADD 396 + R VRF + A V TF+EL H L HE L ALRD DD Sbjct: 3920 HARGTVRFADGLEALRADGVSTFLELGPHAVLCALGHETLESEAVAFLPALRDGRDD 3976 >tr|Q0RIF5|Q0RIF5_FRAAA Tax_Id=326424 SubName: Full=Putative type I polyketide synthase; EC=2.3.1.-;[Frankia alni] Length = 6432 Score = 165 bits (418), Expect = 3e-38 Identities = 134/448 (29%), Positives = 194/448 (43%), Gaps = 31/448 (6%) Query: 14 PVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAELI 73 PVLLS PE L +A AL DH+ HP LT ++ L + L+ Sbjct: 1458 PVLLSGPDPEALRRQARALADHLREHPGLTSTDVAGSLLSRTRFDHGAAVFAED-QTTLV 1516 Query: 74 DALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRCA 133 D L + D A++ + R +VF + P FRAE++ C Sbjct: 1517 DRLAGLADGDVADAVLTGQ--RVTGRTVFVFPGQGSQWPEMGRALLAASPVFRAEIEACE 1574 Query: 134 QAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAMWRSFGIAPNVTI 188 +AF + S LL D G+ G +VQP LF M +LAA+WR G+ P+ + Sbjct: 1575 RAFAEHTDWS----LLGVLQGDAGAPGLDRVDVVQPVLFAVMVSLAALWREGGVRPDAVV 1630 Query: 189 GHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCS 248 GHSQGE+AAAYV+G +TL DA R+I +R + +LLAR Sbjct: 1631 GHSQGEIAAAYVAGALTLADAARLITVR-SKALVRIAGGGGMMSIALGADDVRELLARSP 1689 Query: 249 GWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLRA 308 G +++ +N PR ++G ++ ++ + G AR I V Y +HTS + + LR Sbjct: 1690 GDVEIAALNGPRATVVAGAAGALEDLLGRCEQAGIRARRIPVDYASHTSHV----EPLRD 1745 Query: 309 AIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDVE 368 +++ S T + + G + + YW+ NLR VRFD AI AA+ Sbjct: 1746 HLRETFAGLSPRSTPVAFYSSVTGGRVDTATLDPAYWYRNLRQPVRFDPAIRAALDDGCH 1805 Query: 369 TFVELAEHPTLQLAIHENLAALRDEADDRP--AMVVGTSERTATDLGEFTRNLAQLAVHD 426 F+E++ HP L L + + LA DR VV T R F R LA + Sbjct: 1806 RFIEVSPHPVLTLGVDDILA-------DRTVGGAVVATLRRDTDGSAAFRRALAAADLAG 1858 Query: 427 LNYPWECLRAEPDGAQ-ALPLLDFPNTR 453 W A P + LP F TR Sbjct: 1859 AAVSW----ARPIAVRPELPTYAFDRTR 1882 Score = 115 bits (287), Expect = 4e-23 Identities = 129/429 (30%), Positives = 170/429 (39%), Gaps = 44/429 (10%) Query: 599 WLV--TVGGEAATAADGPPDPVHAAASAGFRSIGAEHPG-VGFRHLDLPAGATAQDWAHP 655 WL + G T +P A + R++ AEHPG V H+D PA Sbjct: 2309 WLAEPALTGTRLTIVLAADEPASATVTGLVRTVAAEHPGRVTLVHVDAPAP--------- 2359 Query: 656 IVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNLGLEFCDHF 715 VA L +EPE A R R+ VLI GGTG LG Sbjct: 2360 -VAVLVAVDEPEAAVRADELLVPRLVRGTFEDAEAVAFTGT-VLITGGTGALGGLVARRL 2417 Query: 716 AHRGAR-RITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTP 774 A + + L SRSG +AA A LA A AQ+ V CD+ D LAA P Sbjct: 2418 AGQPEPPHLLLASRSGPAAAGAAELAAELRAAGAQVTVAACDIADR---DELAALLADIP 2474 Query: 775 ADL----IIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSA 830 AD ++H A +T +AL KV + + VL SSA Sbjct: 2475 ADRPLRGVVHTAGVLDDATVEAMTGAQLAHALRPKVDAAWHLHELTADLALDHFVLFSSA 2534 Query: 831 RATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLA 886 AT+G GQ YAA N LDA+A R+ GL ++ WG WT + L A+ A+LA Sbjct: 2535 VATVGAPGQANYAAGNTFLDALAVHRRSRGLPGTAIAWGLWTQASAMTGHLGAADRARLA 2594 Query: 887 AIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLS-PVSETAA 945 GV + A+A+ +R + +V+ D R PL ++L+ PV+ AA Sbjct: 2595 RHGVGEVADEGALAVLDRRTEPHLVVSTLDEAVLRAEAVAGRLRPLFADLVRVPVAGRAA 2654 Query: 946 PAEP-ADLPGRLSNXXXXXXXXXXXXXXDTSVPMVA----------------LGLDSLQA 988 A+ A GRL V V LG DSL A Sbjct: 2655 GADAGAGWAGRLRAERPRDRHRAVVELLRAQVAAVLGHDGDAGLAADRAFRDLGFDSLTA 2714 Query: 989 LELRRRVKA 997 +ELR R+ A Sbjct: 2715 VELRNRINA 2723 Score = 108 bits (271), Expect = 3e-21 Identities = 99/315 (31%), Positives = 133/315 (42%), Gaps = 24/315 (7%) Query: 698 VLIIGGTGNLGLEFCDHFAHR-GARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCD 756 VL+ GGTG LG E H R G R + LVSRSG + A R+ + A++ V CD Sbjct: 4177 VLLTGGTGALGRELARHLVQRHGVRNLVLVSRSGPAHPDAARVEAELAGLGARVLVLACD 4236 Query: 757 VGDPAAVSRLAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAF 816 V ++ L A P +IHAA ++ D + K + + LD Sbjct: 4237 VTRREDLAELIAG-LDAPLSAVIHAAGTTEDAVVERLSEAAVDAVVAVKALA-ARHLDEL 4294 Query: 817 PRTDGC-RIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHF 875 R D VL S +G GQ YAAAN LDA+ H R GL +++ WG+W V Sbjct: 4295 TRGDELDAFVLFGSIAGILGTAGQGNYAAANSALDAVGHERRRAGLSALTIHWGRWEVDT 4354 Query: 876 ----DLDASSMAQLAAIGVIPMPPAEAIAL--GMQRLGRNAIVAAFDFDRARPVLETFGY 929 L +A+L G+ M AE +AL R G ++VAA RA L G Sbjct: 4355 GMAGGLTERDLARLERAGIGSMTVAEGLALFDRALRAGVPSVVAANLHPRAIGRLGRSG- 4413 Query: 930 GPLVSELLSPVSETAAP-----AEPADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLD 984 P + AP A AD+ G + + D V LG D Sbjct: 4414 --------EPATRARAPLAAVAATQADVAGLVLDTVAEVLGHPSRADIDADRAFVELGFD 4465 Query: 985 SLQALELRRRVKAEF 999 SL A++LR R+ A F Sbjct: 4466 SLMAVDLRNRLTAAF 4480 Score = 105 bits (262), Expect = 3e-20 Identities = 99/378 (26%), Positives = 154/378 (40%), Gaps = 9/378 (2%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRA 70 G +P+LLSA T L ++A+AL D +A+ P + A Sbjct: 3224 GPVPLLLSARTESALQAQASALGDLLASAG--APALVDVAFTLARHRTQFTERAAVLVDA 3281 Query: 71 E-LIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEV 129 + ++ AL+A+ HPAL R A +R+ +F + A+ A Sbjct: 3282 DTVLPALRALAGGTAHPAL-RRGRAQPDQRLALLFTGQGSQRRGMGAGLLAASTAYAAAF 3340 Query: 130 DRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNVTIG 189 D A + G + L+D + QPALF AL M S G+ P++ +G Sbjct: 3341 DEVAAHLDPL-LGVRLHDLVDGDADRLRQTRYAQPALFALQVALYRMVESHGLTPDLLLG 3399 Query: 190 HSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCSG 249 HS GE+AAA+V+G + L DA ++ R + E DL+A G Sbjct: 3400 HSVGELAAAHVAGILGLSDACALVAARGELMQSAREGGAMAAFAATEDE-AGDLVAETGG 3458 Query: 250 WAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLRAA 309 ++ VN P V +SG+ + V +V +GG A + V + H+ + D + RA Sbjct: 3459 RVAVAAVNGPASVVLSGDADAVDQLVARWKDGGRRATRLAVSHAFHSPHMDDVLARWRAV 3518 Query: 310 IQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDVET 369 + + P+ G A E+ DYW LR VRF A+ AA Sbjct: 3519 LAEVTFAPAATSIVSTLTGRIADA---EEMSGADYWLEQLRRPVRFADAVRAAHGAGTTR 3575 Query: 370 FVELAEHPTLQLAIHENL 387 FVEL +L + + + Sbjct: 3576 FVELGPDGSLSAMVQDTV 3593 Score = 97.1 bits (240), Expect = 1e-17 Identities = 100/331 (30%), Positives = 138/331 (41%), Gaps = 35/331 (10%) Query: 596 TDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPG-VGFRHLDLPAGATAQDWAH 654 T +VT G AA D P A R+ AE+PG + +D + A Sbjct: 5853 TSLVVVTRGAVAAGGGDAVPRLSDAPVWGLVRTAQAEYPGRISLIDVDGRPDSLA----- 5907 Query: 655 PIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH------VLIIGGTGNLG 708 ++ A +LA R G Y R+ VL+ G G LG Sbjct: 5908 -LLPDAIAARPAQLALRRGRAYRPRLRAVPSPGPRPGPRPGTGRFGAGTVLVTGAGGALG 5966 Query: 709 LEFCDHFA-HRGARRITLVSRSGESAAVAERLA-QLRSATAAQIAVTRCDVGD-PAAVSR 765 A GAR + LVSR G++ LA +LRSA+ Q+ V CD+ D AA + Sbjct: 5967 GVVARQLALAHGARHLLLVSRRGDADPGLHALAGELRSASV-QVTVAACDLADHDAAQAL 6025 Query: 766 LAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKV--------VGIGQVLDAFP 817 LA P ++HAA + +T + D L K+ + G LDAF Sbjct: 6026 LAGVGTEHPLTAVVHAAGVLDDAILAGMTAEQVDRVLRPKIDAAWNLHRLTAGSGLDAF- 6084 Query: 818 RTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHF-- 875 VL SS +G GQ YAAAN LDA+A RA GL S+ WG W Sbjct: 6085 -------VLFSSIAGIVGNAGQGAYAAANTFLDALASHRRAVGLPATSLAWGPWETGMAG 6137 Query: 876 DLDASSMAQLAAIGVIPMPPAEAIALGMQRL 906 +L A+ ++L +G++P+ E +AL Q L Sbjct: 6138 ELAAADRSRLGRLGLLPLTVDEGLALLDQAL 6168 Score = 85.1 bits (209), Expect = 5e-14 Identities = 106/465 (22%), Positives = 164/465 (35%), Gaps = 33/465 (7%) Query: 13 IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAEL 72 +P +LSA TP+ L +A LR H+ P ++ L TR EL Sbjct: 5004 LPWVLSARTPDGLRRQAVRLRQHLLDEPGQRAADVALSLATTRSAFEHRAVVLGRTREEL 5063 Query: 73 IDALQ--AMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXL------------- 117 I L+ A +D P + P + VF Sbjct: 5064 ISGLERIAALDAIAGPGPVEVVPPGPSGALPLVFAGQPVTGARAVLFSGQGSQRVGMGTG 5123 Query: 118 FYESVPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMW 177 Y++ + A D F + + R + Q ALF AL + Sbjct: 5124 LYQAFGVYAAAYDAVCDEFARVAGLNVRAVVTGAQPGRLDQTRYTQAALFAVEVALFRLL 5183 Query: 178 RSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDR 237 S+G+ ++ GHS GE+AAA+VSG + L DAV ++ R Sbjct: 5184 ESWGLPADLVAGHSIGELAAAHVSGALRLADAVTLVAARGGLMDELPGGGAMVSVRASAD 5243 Query: 238 ETCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTS 297 E L + + L+ VN PR V ISG+ V + L E G R + V + H++ Sbjct: 5244 EV-RSLAEQAASRVDLAAVNGPRSVVISGDETEVVELAARLAERGHRTRRLSVSHAFHSA 5302 Query: 298 LIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDK 357 + ++ R A P + AP L +W +R VRF Sbjct: 5303 RMDPMLERFRDAAGRPATGPMTRTLVSTLTAREVDAP---TLGSAGHWVDQVRGTVRFAD 5359 Query: 358 AIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMV-VGTSERTATDLGEFT 416 A+ + TF+E+ LA L D+ + +V + +R +L Sbjct: 5360 ALTRLRELGAATFLEVGPDAV--------LAPLADDCELGDGVVALAALDRRHGELAAIG 5411 Query: 417 RNLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 +A+ + + + W L D A +PL P RLWL Sbjct: 5412 SFVARAFIAGVRWDWRALFG--DDAVTVPL---PTYAFARERLWL 5451 Score = 64.7 bits (156), Expect = 6e-08 Identities = 62/233 (26%), Positives = 87/233 (37%), Gaps = 27/233 (11%) Query: 157 GSAGIVQPALFTQMAALAAMWRSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIR 216 G QPALF A + S+G+ P + GHS GEVAAA+ +G + L A R+I R Sbjct: 582 GQTRYTQPALFAVEVATFRLLASWGVEPALVAGHSIGEVAAAHCAGILDLPSAARMITAR 641 Query: 217 XXXXXXXXXXXXXXXXXXXDRETCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVD 276 E LLA A L+ VN P V ++G R + + Sbjct: 642 GRLMQRLPGGGAMLAVAAPQHE-ISVLLAGHEEVAGLAAVNGPSSVVVAGARAALDAVRA 700 Query: 277 TLTEGGTFARVIRVRYPAHTSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAP-- 334 + G R + V + H+ L+ ++ RA + G T AP Sbjct: 701 AAADRGYRTRWLEVSHAFHSPLMEPMLEEFRA----------------ELAGITFRAPVI 744 Query: 335 -----ITSELP---VGDYWFWNLRNIVRFDKAIAAAVQRDVETFVELAEHPTL 379 +T EL DYW + R V FD + + VE TL Sbjct: 745 PFVSTVTGELADAGDADYWVEHARRPVLFDAGLHRLHELGAAILVEAGPGRTL 797 >tr|C9YYI1|C9YYI1_STRSW Tax_Id=680198 SubName: Full=Putative type I polyketide synthase;[Streptomyces scabies] Length = 4970 Score = 165 bits (418), Expect = 3e-38 Identities = 132/462 (28%), Positives = 195/462 (42%), Gaps = 31/462 (6%) Query: 9 PDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXT 68 P +P LLS TPE L +A L + P+L P + L Sbjct: 2022 PVAAVPWLLSGRTPEALREQAARLHARLTDRPELRPHDVGLTLATARSAFEHRAVVVGAD 2081 Query: 69 RAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 +A L+ L A+ + PA++ A R + +VF +S P F Sbjct: 2082 QATLLTGLAALAAGQDDPAVVHGTVATPGRTV-FVFPGQGSQWAGMAVGLLDSAPVFAER 2140 Query: 129 VDRCAQAFEAQSC--------GSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSF 180 V +C +A G P + LD+ +VQP LF+ M +LAA+WRS Sbjct: 2141 VAQCERALSPYVDWSLTDVLRGGPDSPPLDR-------VDVVQPVLFSVMVSLAALWRSH 2193 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ P+ IGHSQGE+AAA V+G ++LED R++ +R D + Sbjct: 2194 GVEPSAVIGHSQGEIAAAVVAGALSLEDGARIVALRSRILTTLVDRGAMLFVALPD-DRV 2252 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 + +A G ++ VN P V +SG+ E ++ D L+E G V+R P T H Sbjct: 2253 RERMAPWDGRLSVAAVNGPAAVTVSGDPEALEEFGDRLSEDG----VMRWMIPGVTFAGH 2308 Query: 301 D-GADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAI 359 D LR + D L + TD+ G + + +YW+ NLR V F +A+ Sbjct: 2309 SPQVDGLRRELLDALAGVTPRRTDVAFYSTVTGGALDTTALDTEYWYRNLREPVEFHRAL 2368 Query: 360 AAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNL 419 AA V +TFVE++ HP L + + ++L EA D +V GT F L Sbjct: 2369 AALVDAGHDTFVEVSPHPVLAVWVEKSL-----EAADVAGLVTGTLHTDDGGPARFLTAL 2423 Query: 420 AQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 A VH + W + A G A P ++ P R WL Sbjct: 2424 AGPHVHGVPVDWRAVFA---GTDARP-VELPTYAFQRRRYWL 2461 Score = 132 bits (331), Expect = 3e-28 Identities = 101/350 (28%), Positives = 154/350 (44%), Gaps = 32/350 (9%) Query: 120 ESVPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRS 179 +S P F A + C +A S + L + D +VQPAL+ M +LAA+WRS Sbjct: 584 DSSPVFAARMADCERALAPHVDWSLTDVL--SSATDLERVDVVQPALWAVMVSLAALWRS 641 Query: 180 FGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRET 239 G+ P+ +GHSQGE+AAA V+G ++LED +V+ +R Sbjct: 642 AGVEPDAVLGHSQGEIAAAVVAGALSLEDGAKVVALRSQAITAIAGRGGMASVPLPP--- 698 Query: 240 CEDLLARCSGWA---QLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHT 296 E+L W ++ N P +SG+ E + G+V L AR I V Y +H+ Sbjct: 699 -EELAGHLGPWGDRLSVAAANGPAATVLSGDTEAIDGVVAALRAEDVRARRIPVDYASHS 757 Query: 297 SLIHDGADKLRAAIQD----QLQHPSFVDTDIDCL-GATLGAPITSELPVGDYWFWNLRN 351 + + + ++L + D + P F D++ TL A +YW+ NLR Sbjct: 758 AHVEEIRERLLECLADIEPTAGRVPFFSTVDLNWQDSGTLDA---------EYWYRNLRQ 808 Query: 352 IVRFDKAIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATD 411 VRF++A + + FVE + HP L + I + EA++ A+ VGT R Sbjct: 809 TVRFEEATRTLLAQGFRFFVESSAHPVLTVGISQTA-----EAEECDAVAVGTLRRDQGG 863 Query: 412 LGEFTRNLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 L F +LA+ L W+ L A G +D P R WL Sbjct: 864 LDRFLLSLAEAHTGGLAPDWDTLLAGHPG----DTVDLPTYPFQRRRYWL 909 Score = 124 bits (312), Expect = 5e-26 Identities = 143/496 (28%), Positives = 192/496 (38%), Gaps = 43/496 (8%) Query: 563 LPETPKLDGRAAAAE--VGGFFSNRAWWPGVDTGVTDCWLVTVGGEAA-TAADGP-PDPV 618 +P P+ GRA A G + W D+ D LV V + T+ADG PD Sbjct: 4396 VPAAPEGQGRADAVRHVTGRTLTLVQDWLA-DSTFADAKLVLVTRDGVPTSADGDAPDLT 4454 Query: 619 HAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAALHTANEPELAYRDGAFYAK 678 HAAA RS E+PG F DL ++D VA+ EP+LA R+G + Sbjct: 4455 HAAAWGLARSAQTENPG-RFVLADLDGTRASRDALTAAVAS----GEPQLALREGRAHIA 4509 Query: 679 RIXXXXXXXXXXXXXC--PEHVLIIGGTGNLGLEFCDHF-AHRGARRITLVSRSGESAAV 735 R+ P VLI GGTG +G H A G +R+ L SR G +A Sbjct: 4510 RLARVPAAEQAETPDWGRPGTVLITGGTGAIGSVLARHLVAEHGVKRLLLTSRRGPAAEG 4569 Query: 736 AERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRST-PADLIIHAAVAYASVEFSDIT 794 L +A A V CD D A++RL P ++H A A +T Sbjct: 4570 TADLVVDLAALGAHAEVVACDAADRDALARLLGSLPDAHPLTAVLHVAGTIADGVVDAMT 4629 Query: 795 TDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAH 854 D AL KV + + D V+ SS GG GQ YAAAN LDA+AH Sbjct: 4630 PGRLDTALRPKVDAAWNLHELTEDMDLSAFVVFSSIAGIFGGMGQGNYAAANSFLDALAH 4689 Query: 855 RLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLAAIGVIPMPPAEAIAL--GMQRLGR 908 RA GL S+ WG W + LD + ++A G++ PAE AL G Sbjct: 4690 HRRANGLPAASLAWGLWANKSGMSGGLDEADFRRIARGGIVAFSPAEGAALFDSANATGE 4749 Query: 909 NAIV-AAFDFDRARPVLETFGYGPLVSELLSP----------VSETAAPAEPADLPGR-- 955 ++ D T G L+ L+ P V+ AA L G+ Sbjct: 4750 PVVLPLRLDTGALAAQTGTGGVPALLRGLVRPPARRSAAVGEVAPDAADTLRRTLAGQPE 4809 Query: 956 ----------LSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRRVKAEFDHELEV 1005 + D ++ LG DSL A+ELR R+ A L Sbjct: 4810 QRRERTLLDLVRGHAATVLGFPGPASVDAERGLLELGFDSLTAVELRNRLGAATGLRLPA 4869 Query: 1006 SDLLGGASIADVLAQL 1021 + L + A + QL Sbjct: 4870 TLLFDHPTSAAIARQL 4885 Score = 117 bits (293), Expect = 8e-24 Identities = 130/465 (27%), Positives = 178/465 (38%), Gaps = 38/465 (8%) Query: 592 DTGVT-DCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQ 650 D GVT W T G D P R EHP +DLP + Sbjct: 1092 DAGVTAPLWCATRGAVTTGRDDAVTSPGQHMVWGLGRCAALEHPQRWGGLVDLPGTLDER 1151 Query: 651 DWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLG 708 A +E ++A R Y +R+ VL+ GGTG +G Sbjct: 1152 AAARLCGILAGRDDEDQVAVRHSGAYGRRLVRARPAGPARADAWQPRGTVLVTGGTGGVG 1211 Query: 709 LEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAA 768 A GA + LV R G A L +A ++ V CDV D ++ L A Sbjct: 1212 AHLARWLAEGGAEHLVLVGRRGADTPGAADLTAELTALGTRVTVAACDVADRDRLAELVA 1271 Query: 769 --QHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVL 826 + + +IHAA V SD D+ + LYAKV G + F R D VL Sbjct: 1272 GLEQDGSRIGTVIHAAGTGQLVPLSDTDPDEFADILYAKVAGAENLDAVFDRDDLDSFVL 1331 Query: 827 CSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASS---MA 883 SS G YA+AN LDA+A R RA G SV WG W ++ Sbjct: 1332 FSSISGVWGSGDHGAYASANAHLDALADRRRARGRTATSVVWGIWDPEGGAGMAANLVEE 1391 Query: 884 QLAAIGVIPMPPAEAIALGMQRLGRN----AIVAAFDFDRARPVLETFGYGPLVS---EL 936 QL G+ M P A+ G++++ + +V A D+DR PV + PL+ E+ Sbjct: 1392 QLRGRGIPFMAPRVALT-GLRQVLTDDETVVLVTAVDWDRFAPVFTSARPSPLIGDLPEV 1450 Query: 937 LSPVSETAAPAE-----------------PADLPGRLSN-XXXXXXXXXXXXXXDTSVPM 978 ++E AP + PAD L++ D P Sbjct: 1451 RRALAEETAPGQDGDDTASSLRDRIADLPPADRDRLLTDLVRAHAAAVLGHGSADAIAPE 1510 Query: 979 VA---LGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQ 1020 A LG DSL A+E+R R+ A L ++ L AS AD LA+ Sbjct: 1511 RAFRELGFDSLTAVEMRNRLNAATGLRLPLTVLFDYAS-ADALAR 1554 Score = 117 bits (293), Expect = 8e-24 Identities = 132/486 (27%), Positives = 174/486 (35%), Gaps = 35/486 (7%) Query: 552 TGADVNTLVIL-LPETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVT-DCWLVTVGGEAAT 609 T D L +L L E P DG A G + D G+ W T G + Sbjct: 2606 TAPDGGVLSLLALAEQPYADG--TALPTGLALTTTLLQALGDAGINAPLWSATCGAVSVG 2663 Query: 610 AADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAALHTANEPELA 669 +D P A G E+P LDLP+ + E ++A Sbjct: 2664 RSDALTAPAQATLWGLGAVAGVEYPERWAGMLDLPSDLDERAGVRLAAVLAGLDGEDQIA 2723 Query: 670 YRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLEFCDHFAHRGARRITLVS 727 R Y +R+ VLI GGTG LG A GAR + L Sbjct: 2724 IRPSGVYGRRLVRARPAEETTADAFDPDGTVLITGGTGALGAHVARRLARSGARHLLLTG 2783 Query: 728 RSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQ-HRSTPADLIIHAAVAYA 786 R G A L + A+ V CD D A++ L A P ++HAA Sbjct: 2784 RRGPDTPGAAELVAELAGLGAETTVAACDAADRDALATLLADIPEDRPLRTVVHAAGLLD 2843 Query: 787 SVEFSDITTDDADNALYAKVVGIGQVLDAFPRT-DGCRIVLCSSARATIGGRGQVMYAAA 845 +T + A L K+ LDA R D VL SS T+GG GQ YAAA Sbjct: 2844 DGVLDTLTPERAAGVLRPKM-DAALNLDALTRDLDLTAFVLFSSLAGTLGGTGQGSYAAA 2902 Query: 846 NRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIALGMQR 905 N LDA+A + R+ GL SV WG W D S+ +L G+ PM P A+ Q Sbjct: 2903 NAFLDALAEQRRSLGLPATSVAWGLWAGDSAAD-SARERLVRNGLPPMDPELAVTALEQA 2961 Query: 906 LGR---NAIVAAFDFDRARPVLETFGYG------PLVSELLSPVSETAAPAEPADLPGRL 956 +GR ++ F +DR P P V ++L+ E L RL Sbjct: 2962 MGRAEPRLVLCDFAWDRFAPAYTALRPSAALRDLPDVRDVLAATGADRQETEADSLAARL 3021 Query: 957 SNXXXXXXXXXXXXXXDTSVPMVA----------------LGLDSLQALELRRRVKAEFD 1000 + T V V LG DSL A++LR R+ Sbjct: 3022 AALSPQERQEELTRLVATEVAAVLGHPDPAGIDPDRVFKDLGFDSLTAVDLRNRLSEATG 3081 Query: 1001 HELEVS 1006 L V+ Sbjct: 3082 LRLSVT 3087 Score = 94.7 bits (234), Expect = 6e-17 Identities = 111/474 (23%), Positives = 178/474 (37%), Gaps = 42/474 (8%) Query: 10 DGTI-PVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXT 68 DGT+ P LLSA + L ++A L +H A P L P I+ L + Sbjct: 3577 DGTVLPWLLSARSRAALRAQAQRLLEHTDARPGLRPAAIAHTLATGRSAFEYRGAVVGDS 3636 Query: 69 RAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 R L L+A+ + T A+ ++ ++F Y P F Sbjct: 3637 REALTGGLKALATAGSASGV--TQGTAVAGKVAFLFAGQGSQRAAMGAELYARYPVFADA 3694 Query: 129 VDR-CAQAFEAQSCGSPRNYLLDKNFQD--------DGSAGI-----VQPALFTQMAALA 174 D CA+ + LLD+ ++ D +A + QPALF AL Sbjct: 3695 FDEICAEL----------DPLLDRPLREVVFAAAGSDAAARLDRTEYTQPALFAVEVALF 3744 Query: 175 AMWRSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXX 234 + +G+ P++ +GHS GE+AAA+V+G +T A ++ R Sbjct: 3745 RLVEHWGVVPDLLLGHSIGELAAAHVAGVLTAPHAAALVAARGRLMQALPEGGAMVALTA 3804 Query: 235 XDRETCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPA 294 + + LLA G ++ VN P V +SG+ + V + + + G AR + V + Sbjct: 3805 SEADATA-LLAPYDGRVAVAAVNGPASVVVSGDEDAVLDLAEQWRDRGGKARRLTVSHAF 3863 Query: 295 HTSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVR 354 H+ + D+ R + + D G L P +L +YW ++R VR Sbjct: 3864 HSPHMDAMLDEFRRVAESLDYRAPRIPLVSDVTG-ELATP--EQLGSPEYWVRHVREAVR 3920 Query: 355 FDKAIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRP------AMVVGTSERT 408 F + T++EL +L + LA D P +V + Sbjct: 3921 FHDGMRRLAAEGAVTYLELGPDGSLTAMGRDCLAEADPIDSDDPVDPSAVGPLVPLLRKD 3980 Query: 409 ATDLGEFTRNLAQLAVHDLNYPW-ECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 T++ T LAQL V W L A G + ++ P R WL Sbjct: 3981 RTEIRALTDALAQLYVRGTAVDWPTVLEATGRGGR----VELPTYAFQRERYWL 4030 >tr|Q0QMN7|Q0QMN7_9ACTO Tax_Id=358765 SubName: Full=Polyketide synthase type I;[Streptomyces sp. Eco86] Length = 4290 Score = 164 bits (416), Expect = 5e-38 Identities = 129/461 (27%), Positives = 198/461 (42%), Gaps = 26/461 (5%) Query: 7 RLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXX 66 +L G +PV+LS T L ++A L HV HP T + A Sbjct: 1501 QLRPGPVPVVLSGHTGAALRAQAERLATHVETHPAATVRQV-ARAAAGRAALTHRAVVTA 1559 Query: 67 XTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFR 126 +L L+A+ + P L+ A + R +VF ++ P F Sbjct: 1560 DDPTDLARRLRALATDQDDPGLVHGQ-ADVDPRTVFVFPGQGAQWAGMAVELLDASPVFA 1618 Query: 127 AEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAMWRSFG 181 A + CA A + S LLD + G+A +VQP + M +LAA+WRSFG Sbjct: 1619 ARMAECAAALGEFTDWS----LLDVVRGEGGAASLERVDVVQPVSWAVMVSLAALWRSFG 1674 Query: 182 IAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCE 241 + P+ +GHSQGE+AAA V+G ++L DA +V +R E E Sbjct: 1675 VEPDAVVGHSQGEIAAACVAGALSLRDAAKVSALRSAALRDLAGTGGMMSVALPAAEV-E 1733 Query: 242 DLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHD 301 LA G ++ VN P V ++G+ ++G+ LT G +AR++ V Y +H+ + Sbjct: 1734 RRLAGRDGRVSVAAVNGPAAVVLAGDPAALEGLAAELTADGVWARLVAVDYASHSPQV-- 1791 Query: 302 GADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAA 361 +++R + D+L DI G PI + +YW+ NLR+ VRF++A+ A Sbjct: 1792 --ERIRTTLLDRLAGLEPRTADIPFYSTVTGEPIDTAALDAEYWYRNLRHTVRFEEAVRA 1849 Query: 362 AVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQ 421 +VE++ HP L A+ + + E+ A+VVGT R F R+LA+ Sbjct: 1850 LDGAGHRAYVEVSPHPLLTAAVQDTV-----ESTGSTAVVVGTLRRDQGGPDRFLRSLAE 1904 Query: 422 LAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLP 462 V + W P P D P WLP Sbjct: 1905 AYVRGVPVDW-----TPATGTGGPRPDLPAYAFQRQHYWLP 1940 Score = 144 bits (364), Expect = 5e-32 Identities = 113/420 (26%), Positives = 178/420 (42%), Gaps = 27/420 (6%) Query: 13 IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAEL 72 +PV LS T + L ++A L H+ HPD I+ +L Sbjct: 3206 VPVALSGHTEDALRAQAARLAAHLTTHPDTPLRDIAFTAASGRAALDHRAVVLADDPEQL 3265 Query: 73 IDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRC 132 + L A+ + + P ++R A RR+ +VF ++ P F A + C Sbjct: 3266 GERLTALAEGRDVPDVVRGTAAPNARRVAFVFPGQGSQWAGMALELLDAAPVFAARLTEC 3325 Query: 133 AQAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAMWRSFGIAPNVT 187 A A EA + S +LD Q G+ G +VQP F +LAA+W++ G+ P+ Sbjct: 3326 AAAVEAHADWS----VLDVLRQVPGAPGLDRVDVVQPVTFAVTVSLAALWQAHGVRPDAV 3381 Query: 188 IGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARC 247 IGHSQGE+AAA V+G ++L DA V+ +R E E Sbjct: 3382 IGHSQGEIAAACVAGALSLADAAAVVCLRSRALTRLSGKGGMMSVALPASEVRE---LFT 3438 Query: 248 SGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHT---SLIHDGAD 304 ++ VN P +SG+ ++ + G AR+I V Y +H+ + + D D Sbjct: 3439 DDRLHVAAVNGPASTVVSGDPSALEDLRARCDARGVRARLIAVDYASHSPHVTTVKDELD 3498 Query: 305 KLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQ 364 L A I + ++ G + G YW+ NLR VRF A+ AA+ Sbjct: 3499 GLLAGIAPRA-------VPVELYSTVTGQRLDPRELTGAYWYTNLRQTVRFADAVGAALD 3551 Query: 365 RDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAV 424 + TF+E++ HP + + E + +A A+V+ T R FTR+LA+ V Sbjct: 3552 AGIGTFLEVSPHPVVAPGVQETV-----DAAGARAVVLSTLRRDDGGRPRFTRSLAEAHV 3606 Score = 134 bits (337), Expect = 7e-29 Identities = 125/419 (29%), Positives = 164/419 (39%), Gaps = 39/419 (9%) Query: 605 GEAATAADGPP-DPVHAAASAGFRSIGAEHPG--VGFRHLDLPAGATAQDWAHPIVAALH 661 G TAAD PP DP AA R+ EHP V D PA ++ L Sbjct: 2306 GAVGTAADTPPPDPATAAVWGLIRTAQTEHPDRFVLVDTDDRPASTA-------LLPRLA 2358 Query: 662 TANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNLGLEFCDHFAHR-GA 720 EP+LA RDG R+ VLI G TG LG H R G Sbjct: 2359 GTGEPQLALRDGRVLVPRLTPVTDDPGVSPWTATGTVLITGATGTLGRLVARHLVDRHGV 2418 Query: 721 RRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIH 780 R + L SRSG+ A A ++ V CDV + V+ L A H P ++H Sbjct: 2419 RDLVLASRSGQDAPGTAAFTDDLRALGVRVTVVACDVAERDEVAALLAAH---PVTAVVH 2475 Query: 781 AAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQV 840 AA + +T + + AKV G + LD VL SS T+G GQ Sbjct: 2476 AAGVLDDAVLTALTPERVTDVCRAKVDG-ARHLDELTGPGLTAFVLFSSVAGTLGNAGQA 2534 Query: 841 MYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLAAIGVIPMPPA 896 YAAAN LDA+A R RA GL S+ WG W + +D + A+LA GV+P+ Sbjct: 2535 AYAAANAALDALAERRRAAGLPATSIAWGLWAESSRMTGHMDDTDRARLARAGVLPLDTD 2594 Query: 897 EAIALGMQRLGRNA---IVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPAEPADL- 952 + R+ + A D + R PL+S L+ V AA PAD Sbjct: 2595 TGLTAFDVATARDVPAVLAAPLDREALRARASEGTLPPLLSSLVPVVRRAAAADGPADAA 2654 Query: 953 -----------PGRLSNXXXXXXXXXXXXXXDTSV-----PMVALGLDSLQALELRRRV 995 P R+ D + P +G DSL ++ELR R+ Sbjct: 2655 DALRRRLAEQDPLRVLQDVVLTQAAVVLGHPDPAALGPDRPFKEIGFDSLTSVELRNRL 2713 Score = 107 bits (267), Expect = 9e-21 Identities = 103/353 (29%), Positives = 146/353 (41%), Gaps = 11/353 (3%) Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPA--GATAQ 650 T WLVT G D P DP A R E+P +DLPA A A Sbjct: 3759 TATLPLWLVTAGAVGTGDTDPPHDPDAAQVWGLGRVAMLEYPTFWGGLVDLPARPDADAL 3818 Query: 651 DWAHPIVAALHTANEPELAYR-DGAFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGNLGL 709 + I+A +E +LA R G + + + ++ GGTG LG Sbjct: 3819 EELRTIMAG-GFGDEDQLAVRASGTLLRRLVRAPLDGTPAVGWQARDTAVVTGGTGALGP 3877 Query: 710 EFCDHFAHRGARRITLVSRSG-ESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAA 768 E A GA + LVSRSG E+ VAE ++L A ++ CDV D AAV+ L Sbjct: 3878 EAARWLAGLGAAHVVLVSRSGPEAEGVAELTSEL-DARGVRLTAHACDVADRAAVAALLT 3936 Query: 769 QHRSTPADL--IIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVL 826 R + ++HAA D + L AKV G ++D R + +V Sbjct: 3937 GLRDQGEKVRTVLHAAALMRLAALPDTDLAEYAAVLDAKVQGARHLVDLLDRDELDALVF 3996 Query: 827 CSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT-VHF--DLDASSMA 883 SS G YAAAN LDA+A + RA+GL SV WG W F +DA + Sbjct: 3997 YSSIAGVWGSGDHGAYAAANATLDALAEQARADGLPVTSVAWGVWDGARFPEGVDAGQLR 4056 Query: 884 QLAAIGVIPMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSEL 936 + + P E + + ++R +A D+ P+ + PL +E+ Sbjct: 4057 RQGLPLIHPESALEGLRVVLERGESGLSMADVDWAAFMPLFASARSRPLFAEI 4109 Score = 92.8 bits (229), Expect = 2e-16 Identities = 108/459 (23%), Positives = 176/459 (38%), Gaps = 44/459 (9%) Query: 10 DGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTR 69 DG + V +SA TP L TAL D + +P ++ L T Sbjct: 487 DGPVLVPVSARTPAAL----TALADRLTTTDAPSPLDLAYSLATTRSPLPQRAVLVADTP 542 Query: 70 AELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEV 129 ++ L+A+ H ++R A R ++F + P + A V Sbjct: 543 GDVPGLLRALAAGEPHARVVRGTAAP--GRTVFLFAGQGNQRPGMGHEIHLRHPVYAAAV 600 Query: 130 DRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIV--------QPALFTQMAALAAMWRSFG 181 + A+ A + LLD ++GS QPALF AL + S+G Sbjct: 601 EEIAEEMRAHL----QRPLLDVMSAEEGSRDAALLDEPEYTQPALFAVQVALFRLVESWG 656 Query: 182 IAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCE 241 + P+ +GHS GE+AA +V+G ++L DA ++ R + E Sbjct: 657 VRPDAVLGHSFGELAALHVAGAMSLPDACALVATRGRLMQHVPPGGASVLVEASEAELTP 716 Query: 242 DLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHD 301 D+ A G ++ +N+P ++G+ E I G R +R+R+ +H++ + Sbjct: 717 DVRA-SGGAVSIAALNTPTATVLAGDEEATLEIARKWERSGRRTRRLRIRFASHSAHMDP 775 Query: 302 GADKLR-AAIQDQLQHP------SFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVR 354 D +R AA + + Q P SF ++D G L ++W + R+ VR Sbjct: 776 ILDGMRQAASRVRWQRPRLRVISSFTGAELDPTG----------LDWPEFWARHTRDTVR 825 Query: 355 FDKAIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGE 414 F A+ A TF+EL TL A A D A + DL Sbjct: 826 FADAVRTACAGGARTFLELGPDGTL-------CAMGPANAPDDVAFAAAMTGGDRPDLRS 878 Query: 415 FTRNLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTR 453 +A++ + W A GA+ +PL +P R Sbjct: 879 LLTAVARVHARGVPVDWTRFHA-GTGARRVPLPTYPFQR 916 >tr|B5L6M3|B5L6M3_MICCH Tax_Id=1874 SubName: Full=Putative type I polyketide synthase;[Micromonospora chalcea] Length = 3953 Score = 164 bits (416), Expect = 5e-38 Identities = 136/452 (30%), Positives = 191/452 (42%), Gaps = 23/452 (5%) Query: 9 PDGT---IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXX 65 PDG + L+SA TP L +A L + H D ++ L Sbjct: 2579 PDGDPTPLAWLVSARTPAALRQQAAGLASYAREHHDTRDADVAWSLATARTTFDHRAVVL 2638 Query: 66 XXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAF 125 R EL+ L A+ +HPA++R D RI VF E P F Sbjct: 2639 GGDRDELLAGLDAVAAGEQHPAVVRADTPTGPARIVLVFPGQGSQWTGMALDLLEQSPVF 2698 Query: 126 RAEVDRCAQAFEAQSCGSPRNYLLDKNFQDD-GSAGIVQPALFTQMAALAAMWRSFGIAP 184 + CA+A + + S + L D G +VQPALF M +LAA+WR+ G+ P Sbjct: 2699 AEHLRACAEAIDRHTDWSLLDVLRGAPGSADLGRVDVVQPALFAVMTSLAALWRAAGVVP 2758 Query: 185 NVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLL 244 + +GHSQGE+AAAYV+G ++L+DA RV+ +R E++ Sbjct: 2759 DAVVGHSQGEIAAAYVAGALSLDDAARVVALRSRILTRIAGLGAMASVSL----AAEEIT 2814 Query: 245 ARCS--GWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDG 302 AR S L+ VN P ++G+ V V G AR+I V Y +H+ + Sbjct: 2815 ARLSEADDVHLAAVNGPHDCVVAGDVTAVGDFVARCVADGVRARLIPVDYASHSPHV--- 2871 Query: 303 ADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPI-TSELPVGDYWFWNLRNIVRFDKAIAA 361 D +R + D L + GAP+ T+EL G YWF NLR+ VRF A A Sbjct: 2872 -DAIRDELLDALGPVRPRAGTVPFYSTLTGAPVDTTELDAG-YWFRNLRHTVRFAAATEA 2929 Query: 362 AVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQ 421 + FVE + HP L + I ++L E R V GT R E LA+ Sbjct: 2930 LLDAGHHLFVEASPHPVLAVGIEQSL-----ERAGRTGQVGGTLRRDQDGAREVLAALAR 2984 Query: 422 LAVHDLNYPWECLRAEPDGAQALPLLDFPNTR 453 VH W + P G+ L L +P R Sbjct: 2985 AHVHGAPVDWTTVL--PRGSARLDLPTYPFQR 3014 Score = 138 bits (348), Expect = 3e-30 Identities = 121/446 (27%), Positives = 179/446 (40%), Gaps = 29/446 (6%) Query: 8 LPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXX 67 L GT+P LLSA + E L +A LR+ A P I L Sbjct: 490 LTGGTLPWLLSARSEEALRRQAARLREFATARPGDRLADIGHALAFEREHHEHRTAVVAD 549 Query: 68 TRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRA 127 T EL+ L A+ D +++ AA R +VF ES P FR Sbjct: 550 TAEELLAGLAAIADGRPAASVVSGHGAAARTV--FVFPGQGSQWDRMAVELSESCPLFRE 607 Query: 128 EVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAMWRSFGI 182 + CA A + S LLD G+ +VQPALF M +LA +W++ GI Sbjct: 608 HLRACADALAPHTDWS----LLDVLHGVPGAPALDRVDVVQPALFAVMVSLARVWQAAGI 663 Query: 183 APNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCED 242 P+ +GHSQGE+AAA+++G + L+ A ++ +R + Sbjct: 664 RPDAVVGHSQGEIAAAHIAGALPLDAAATIVALRSRLLLDLAGTGGMASLPLPAADVERL 723 Query: 243 LLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDG 302 L ++ VN+P ++G + + +V G ARVI V Y +HT+ + Sbjct: 724 LQHPGRDGLSIAAVNAPGSTVVAGPPDALHDLVRACEADGVQARVIPVDYASHTAAVEPL 783 Query: 303 ADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAA 362 ++L AA+ P+ DI AP + YW+ NLR V + A+ A Sbjct: 784 RERLEAALAGIAPVPA----DIAFYSTVTAAPADTGSLDAAYWYRNLRQPVALEPAVRAL 839 Query: 363 VQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQL 422 + F+E++ HP L + E + + PA GT R ++LAQ Sbjct: 840 LSDGHTLFIEVSPHPVLTTPLQETI-----DDSGTPATAHGTLRRDHGGPDRLLQSLAQA 894 Query: 423 AVHDLNYPWECLRAEPDGAQALPLLD 448 VH A PD A LP D Sbjct: 895 HVHG---------ATPDWATVLPRRD 911 Score = 132 bits (332), Expect = 2e-28 Identities = 137/433 (31%), Positives = 172/433 (39%), Gaps = 43/433 (9%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAA 659 LVT G T + PD AA RS AE+PG F+ +D+ A AT Q VAA Sbjct: 3419 LVTRGATGITEQEPVPDLAAAAVWGLVRSAQAENPG-RFQLVDVDATATEQ-----AVAA 3472 Query: 660 LHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPE-----------HVLIIGGTGNLG 708 + + EP+ A RDG Y R+ VLI GGTG LG Sbjct: 3473 VIASGEPQSAVRDGRAYVPRLAWWSATDDASGGADARPALAAAFRPGGTVLITGGTGTLG 3532 Query: 709 LEFCDHF--AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR- 765 H AHR + LVSR G A A LA SA A + V CD D AA++ Sbjct: 3533 GLVARHLVTAHR-VGHLVLVSRGGLDAPGAPELATELSALGASVTVAACDTTDRAALTGV 3591 Query: 766 LAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIV 825 L+A P ++HAA +T + D L KV + + D V Sbjct: 3592 LSAIPGEHPLTGVVHAAGTLDDATVPSLTPERLDTVLGPKVDAAWNLHELTRDLDLSAFV 3651 Query: 826 LCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW----TVHFDLDASS 881 L SSA +G GQ YAAAN LD +A A GL VSV WG W + LD Sbjct: 3652 LFSSAAGVLGAPGQANYAAANSFLDGLARHRHALGLPAVSVAWGPWQQKSALTGGLDEGR 3711 Query: 882 MAQLAAIGVIPMPPAEAIALGMQRLGRN---AIVAAFDFDRARPVLETFGYGPLVSELLS 938 A G++P+P EA+A L + +VA R P++ +L+ Sbjct: 3712 HGGAARRGLVPLPTDEALACFDGVLDADLPTVVVARLHLRELRAQAVADALPPVLRDLVR 3771 Query: 939 PVSETAAPAEP---ADLPGR------------LSNXXXXXXXXXXXXXXDTSVPMVALGL 983 A AEP A L GR L T P LG Sbjct: 3772 VPRRRAESAEPDLAARLVGRDDDEQRAVTVEVLRGHLAAVLGHGSPGDIATDRPFQDLGF 3831 Query: 984 DSLQALELRRRVK 996 DSL ALELR R++ Sbjct: 3832 DSLTALELRNRLR 3844 Score = 95.5 bits (236), Expect = 3e-17 Identities = 97/329 (29%), Positives = 130/329 (39%), Gaps = 29/329 (8%) Query: 698 VLIIGGTGNLGLEFCDHF--AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRC 755 VL+ GGTG LG H AH G R + LVSR G AA A L + A + V C Sbjct: 1755 VLVTGGTGTLGAAVARHLVTAH-GVRHLLLVSRRGIEAAGAAELQAELTGLGADVVVRAC 1813 Query: 756 DVGDPAAVSRLAAQ-HRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLD 814 DV D + RL + P ++H+A + + D L KV Q+ + Sbjct: 1814 DVADREDLRRLLDEIPPEHPLTAVVHSAGVTDDAAVTVLEPRQLDPVLRPKVDAAWQLHE 1873 Query: 815 AFPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT-- 872 D VL SS T+G GQ YAA N LDA+A A GL VS+ WG W Sbjct: 1874 LTAAHDLSAFVLFSSLAGTLGNPGQANYAAGNTYLDALAAHRHARGLPAVSLAWGLWQSA 1933 Query: 873 --VHFDLDASSMAQLAAIGVIPMPPAEAIAL---GMQ---------RLGRNAIVAAFDFD 918 + +L +A + M AEA+AL G+ + A+ AA D Sbjct: 1934 SGITAELFDDKRHAVAHSLLTTMSDAEALALFDVGLDGGRPDLVPAGINLGAVRAAADTR 1993 Query: 919 RARPVLETF---------GYGPLVSELLSPVSETAAPAEPADLPGRLSNXXXXXXXXXXX 969 A VL F G L ++ + + A L + + Sbjct: 1994 AAPAVLRGFLHPTRRQVGGRAARQGALQRELAGRSEAEQQALLLDLVRDNVGAVLNHPAP 2053 Query: 970 XXXDTSVPMVALGLDSLQALELRRRVKAE 998 D P +G DSL A+ELR R+ AE Sbjct: 2054 QTIDPRRPFQEIGFDSLTAVELRNRLNAE 2082 >tr|C1B9P9|C1B9P9_RHOOB Tax_Id=632772 SubName: Full=Polyketide synthase;[Rhodococcus opacus] Length = 3527 Score = 164 bits (415), Expect = 6e-38 Identities = 125/456 (27%), Positives = 188/456 (41%), Gaps = 12/456 (2%) Query: 7 RLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXX 66 R PD + +S T L ++A LR++V+ HPDLTP ++A L Sbjct: 473 RPPDEVVAWFVSGHTEPALRAQAERLREYVSGHPDLTPAAVAAALLGSRATFDHRAAVIG 532 Query: 67 XTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFR 126 L++ L A+ +I R +VF ++ P F Sbjct: 533 AQPHALLNGLDALGRGAPSADVITGVALEAGDRPVFVFPGQGSQWVGMATELLDTSPVFA 592 Query: 127 AEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNV 186 V CA+A + S + L D++ +VQPALF M LAA+WR G+ P Sbjct: 593 DTVRECAEALAPYTNFSLLDVLRDRDPAALDRVDVVQPALFAMMVGLAALWRDHGVEPAA 652 Query: 187 TIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLAR 246 +GHSQGE+AAAYV+G ++L DA V+ R + + + Sbjct: 653 VVGHSQGEIAAAYVAGALSLSDAALVVAARSRVIGASARRGGGMASVTLPADLVREKIQP 712 Query: 247 CSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKL 306 +G +++ +N P ISG + + ++ L G AR I V Y +H + L Sbjct: 713 WAGAVEVAAINGPSATVISGPVDALDLLIGQLQGDGVQARRIAVEYASHCA----DVSVL 768 Query: 307 RAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRD 366 R I D L + + I + G + DYW+ NLR VRF++A + Sbjct: 769 REPILDVLASITPRRSRIPFYSSVTGGVLDGTALDADYWYRNLRRTVRFEQATRSLAADG 828 Query: 367 VETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHD 426 FVE HP L +A+ + L +A VGT R L +FT LA+ VH Sbjct: 829 YRLFVESCSHPVLTVALQDTL-----DAAGVAGRAVGTIRRDRAGLRQFTAALAEAQVHG 883 Query: 427 LNYPWECLR-AEPDGAQALPLLDFPNTRMNEIRLWL 461 L+ W+ + A D + +D P R WL Sbjct: 884 LHVAWDRVGWARRDDRR--QWVDLPTYAFQHRRYWL 917 Score = 120 bits (300), Expect = 1e-24 Identities = 109/341 (31%), Positives = 150/341 (43%), Gaps = 17/341 (4%) Query: 592 DTGVTDCWLVTVGGEAATAADGP-----PDPVHAAASAGFRSIGAEHPGVGFRHLDLPAG 646 D D LV V A DG PD AA S E+P F +DL Sbjct: 2990 DDTFADNPLVIVTRNAVVTDDGQDRDARPDLAAAAVWGLVGSAQNENPD-RFVLIDLDDT 3048 Query: 647 ATAQDWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGN 706 + A+ I++AL + EP++A R+G A R+ VLI GGTG Sbjct: 3049 SDAEA---AIMSAL-ASGEPQVAARNGTLCAPRLRRMAVVDEPTPFDPGGTVLITGGTGT 3104 Query: 707 LGLEFCDHFAH-RGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR 765 +G H GAR + L SR G A ++RL + S A++ + CD D +AV+ Sbjct: 3105 VGSLVARHLVTGHGARHLLLTSRRGPGAEGSDRLRRELSDLGAEVGIVACDTADASAVAG 3164 Query: 766 LAAQHRST-PADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRI 824 L A S P +IHAA + +T + D L KV + +D Sbjct: 3165 LLAGIPSEHPLTAVIHAAGVIDDGTLASLTPERLDTVLRPKVDAAWHLHRLTADSDVRAF 3224 Query: 825 VLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW----TVHFDLDAS 880 V+ SS +G GQ YAAAN LDA+AH A GL +S+ WG W + +L A Sbjct: 3225 VVFSSLAGVLGAPGQANYAAANMFLDALAHHRHALGLPGLSIAWGMWATPSAMTDNLGAI 3284 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNA-IVAAFDFDRA 920 +A+ G++PMP A+ +AL L A VAA FD + Sbjct: 3285 DLARARLSGMVPMPAADGLALFDSALAAGAPTVAAARFDHS 3325 Score = 112 bits (280), Expect = 3e-22 Identities = 117/370 (31%), Positives = 151/370 (40%), Gaps = 32/370 (8%) Query: 553 GADVNTLVILLPETP----KLDGRAAAAEVGGFFSNRAWWPGVDTGVTDCWLVTVGGEAA 608 G D + V+ L P + R+ AA + RAW G D V LVT A Sbjct: 1245 GGDPDGRVLWLDRAPGDEADVPARSHAAAESTLRAVRAWL-GDDCLVETRLLVTTRLAVA 1303 Query: 609 TAADGPPDPVHAAASAGFRSIGA---EHPG-VGFRHLDLPAGATAQDWAHPIVAALHTA- 663 D P D V AA + G IGA EHP + LD AG + P V ++ A Sbjct: 1304 VRDDDPVDDVSAAPAWGL--IGAVQNEHPDRITLVDLDAAAG----ELPDPAVLSMALAC 1357 Query: 664 NEPELAYRDGAFYAKRIXXXXXXXXXXXXX-----CPEHVLIIGGTGNLGLEFCDHF-AH 717 NEP+LA R G A + VLI GGTG +G H A Sbjct: 1358 NEPQLAVRAGVLLAPMLAAVTPATAAPDEGPATFGADGTVLITGGTGTIGRLIARHLVAR 1417 Query: 718 RGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADL 777 G RR+ L R A L + + +A CDV D AV+ L A Sbjct: 1418 HGVRRLVLTGRRLLDDEAASELRAEFAESGTDVAAVACDVADRDAVATLLAGIPDLSG-- 1475 Query: 778 IIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGR 837 +IHAA + ++ + L KV G + D D VL SSA +GG Sbjct: 1476 VIHAAGVLEDATAATLSAEQLHAVLRPKVDGAWNLHDLTRDRDLSAFVLFSSAAGVLGGA 1535 Query: 838 GQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW------TVHFDLDASSMAQLAAIGVI 891 GQ YAAAN LDA+A RA GL S+ WG W T H L+A+ + +L G+ Sbjct: 1536 GQANYAAANVFLDALAQHRRARGLPATSMAWGLWDRPSGMTSH--LNAADLDRLQRNGID 1593 Query: 892 PMPPAEAIAL 901 + P +AL Sbjct: 1594 TISPEAGLAL 1603 Score = 99.0 bits (245), Expect = 3e-18 Identities = 93/370 (25%), Positives = 142/370 (38%), Gaps = 19/370 (5%) Query: 16 LLSADTPELLDSEATALRDHVAAHPDLTPGP--ISAMLFXXXXXXXXXXXXXXXTRAELI 73 +LS T + L ++AT L + + P P ++ L T +L Sbjct: 2210 VLSGKTGDALRAQATRLAEFLDTSETELPDPADLAYSLATTRSGFTHRAAVIGDTLDDLR 2269 Query: 74 DALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRCA 133 D L ++ E P + R + ++F Y++ P F +D Sbjct: 2270 DGLARIVT--ERPGGNVVTGTSARGKTAFMFTGQGAQRIGMGRGLYDAYPVFATALDEVC 2327 Query: 134 QAFEAQSCGSPRNYLLDKNFQDDG----SAGIVQPALFTQMAALAAMWRSFGIAPNVTIG 189 + R + DK DDG S QPALF AL + R +GI P+ IG Sbjct: 2328 AVLDEHVETPVRQVIWDK---DDGAKLDSTEYTQPALFAIEVALYRLLREWGITPDYLIG 2384 Query: 190 HSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCSG 249 HS GE+ AA+V+G +L DA ++G R R ED+L R G Sbjct: 2385 HSIGEITAAHVAGVFSLPDAAALVGDRGRLMQSTKPGLMIAV-----RAREEDILPRIDG 2439 Query: 250 WAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLRAA 309 L+ VN V ++G V + L+ G +RV H++L+ D+ A Sbjct: 2440 RVDLAAVNGAESVVLAGGERDVHAVAAELSAAGLKTTSLRVERAFHSTLMDPILDQFAAV 2499 Query: 310 IQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDVET 369 + P + + G A EL DYW ++R+ VRF + A + V Sbjct: 2500 LSKLTAQPPRIPVVSNVTGRVATA---DELVSPDYWTRHIRHTVRFHDGVRALDELGVTR 2556 Query: 370 FVELAEHPTL 379 VE+ TL Sbjct: 2557 LVEVGPGATL 2566 >tr|D0LQW2|D0LQW2_HALO1 Tax_Id=502025 SubName: Full=KR domain protein;[Haliangium ochraceum] Length = 3930 Score = 164 bits (415), Expect = 6e-38 Identities = 130/438 (29%), Positives = 185/438 (42%), Gaps = 27/438 (6%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 AA P +P LLS T E L ++A L H+ H D +S L Sbjct: 2546 AAATAPVAALPFLLSGKTEEALKAQAQRLHQHLQRHEDAALVDVSYSLATTRAHFEQRAA 2605 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 TR EL+ AL A+ + P+L+ P + ++ +VF S Sbjct: 2606 LVASTREELLAALAALANGESAPSLV-VAPRSADGKVVFVFPGQGSQWQGMGRALLRSSD 2664 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAG---IVQPALFTQMAALAAMWRSF 180 AFRAEV+ C AF GS R L + GS+ ++QP LFT M +LAA WRS Sbjct: 2665 AFRAEVEACEAAFAPYIDGSLREAL------EGGSSDRVDVLQPVLFTMMVSLAAHWRSL 2718 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ +GHSQGEVAAAYV+G ++L+DA +++ +R E Sbjct: 2719 GVVAAAVVGHSQGEVAAAYVAGALSLDDAAQIVALR-SRALRRVAGRGAMAAVELGAEQL 2777 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 LA + VNSPR ++G+ + +++ L E G + + R + +H L+ Sbjct: 2778 ATYLAPFEEQLAIGAVNSPRASLVAGQPAALDALLEKLAEDGVYTQKARGNHASHCRLVE 2837 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 A +L A+Q PS I G + DYW+ NLR V F A Sbjct: 2838 PLAQELTDALQG--IRPS--TCAIPLYSTVTGTRLEGHELDADYWYQNLRAPVLFQSATE 2893 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVV-------GTSERTATDLG 413 + + FVEL+ HP L L ++E +A + A VV GT R LG Sbjct: 2894 RLLADGHDLFVELSPHPVLSLPLYETF-----DAREHSAQVVTSLRRGDGTHARMLLSLG 2948 Query: 414 EFTRNLAQLAVHDLNYPW 431 E +L H PW Sbjct: 2949 ELHNRGHKLDWHAFFAPW 2966 Score = 114 bits (286), Expect = 5e-23 Identities = 99/330 (30%), Positives = 134/330 (40%), Gaps = 34/330 (10%) Query: 698 VLIIGGTGNLGLEFCDHFA-HRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCD 756 VLI GGTG LG H H G R + L+SR G E LA+ + A + + CD Sbjct: 1724 VLITGGTGTLGGLLARHLVQHYGVRHLMLISRRGPGTPGVEALAEELESAGAHVQLLACD 1783 Query: 757 VGDPAAVSR-LAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDA 815 V D AA+ L + P +IHAA S +T + + AKV G + + Sbjct: 1784 VTDRAALQHALEVVPKDHPLTAVIHAAGVIEDSVLSTLTPARLSSVMRAKVAGALHLHEL 1843 Query: 816 FPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHF 875 D +L SS IG GQ YAAAN LDA+A RA GL +++ WG W Sbjct: 1844 TESVDLSTFILFSSLSGVIGSPGQANYAAANTFLDALAQHRRAGGLPALALAWGAWDETS 1903 Query: 876 DLDA----SSMAQLAAIGVIPMPPAEAIALGMQRLGR-NAIVAAFDFDRA---------- 920 +L A + +L +G P+P +AL L + +A V A FDR Sbjct: 1904 ELTAHLTEADRQRLRQMGFHPLPATTNLALFDTALAQPDAAVVAARFDRGSLDKHRNQTL 1963 Query: 921 -------------RPVLETFGYGPLVSELLSPVSETAAPAEPADLPGRLSNXXXXXXXXX 967 RP + E L P+S P E + L Sbjct: 1964 PALFRDLAKQPLDRPRANNLAAHMSLGERLRPLS----PGERQRILLELVQTEVASVLML 2019 Query: 968 XXXXXDTSVPMVALGLDSLQALELRRRVKA 997 D+ P+ GLDSL A+E+R R+ A Sbjct: 2020 SSHNFDSQQPLQKQGLDSLMAVEIRNRLGA 2049 Score = 112 bits (279), Expect = 3e-22 Identities = 121/465 (26%), Positives = 177/465 (38%), Gaps = 47/465 (10%) Query: 601 VTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAAL 660 +T G AA A + PD +HA R+ AEHP + +D ++ ++ AL Sbjct: 3398 LTYGAVAAHAEEDVPDLIHAPLWGLVRAAQAEHPHLPIFLVDSDDTEASR---RTLMNAL 3454 Query: 661 HTANEP-ELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLEFCDHFA- 716 E E R G + VLI GGTG LG H Sbjct: 3455 DELEEGREFILRTGQALIPSLARAARSTDSEMGGLATEGTVLITGGTGTLGSLLARHLVQ 3514 Query: 717 HRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRST-PA 775 H G + + LVSR G +A A LA+ A + + CDV D AA++ L A + P Sbjct: 3515 HHGVKHLVLVSRQGATAEGANSLARELLNAGAAVTLAVCDVTDRAALAELLASIPAAHPL 3574 Query: 776 DLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIG 835 ++H A +T++ + AKV + + + +L SS +G Sbjct: 3575 AAVVHTAGLLEDALIDSLTSEQLHRVMRAKVEAAIHLHELTSASKLSAFILFSSFAGVLG 3634 Query: 836 GRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW----TVHFDLDASSMAQLAAIGVI 891 GQ YAAAN LD +A RA GL +++ WG W + L S + + A G+ Sbjct: 3635 SAGQANYAAANTFLDGLAQHRRARGLPALAIDWGYWADRSAISEHLRDSDLQRFARHGLR 3694 Query: 892 PMPPAEAIALGMQRLGR-NAIVAAFDFDRARPVLETFGYGPLVSELLSP----------- 939 + +AL L R ++ A + D P + L+ L+ P Sbjct: 3695 ALSAETGLALFDAALRRPEPVLVATELDTTLPSRQADALPLLLRRLIQPKALPRTTADTY 3754 Query: 940 -----VSETAAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSVPMVALGLDSLQALELRRR 994 ++E A L + D P+ LGLDSL ALE+R R Sbjct: 3755 SFARDLAELAPEERERALVELVRREAASVLGISSPTTVDPRRPLQELGLDSLMALEIRNR 3814 Query: 995 VKAE----------FDH--ELEVSDLLGGASIA------DVLAQL 1021 + FDH ++ L+GG A VLAQL Sbjct: 3815 LMQATKLRLQATVLFDHPTPAALAQLIGGQMFAAEAGDERVLAQL 3859 Score = 84.0 bits (206), Expect = 1e-13 Identities = 111/467 (23%), Positives = 170/467 (36%), Gaps = 30/467 (6%) Query: 12 TIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAE 71 T PVLLS+ + L S+A L D V D+ ++ L R E Sbjct: 448 TYPVLLSSRSDSGLRSQAQRLLDWVTERADVEVVDVAYSLATTRSHFESRAVVYARDRQE 507 Query: 72 LIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDR 131 L+ +LQA+ P + R R+ +F P FRA ++ Sbjct: 508 LLASLQALTQGA--PGSDASKTRVGRDRLAVLFTGQGSQRARMGAELSALYPVFRASLEE 565 Query: 132 CAQAFEAQSCGSPRNYLLDKNFQDDGSAG--------IVQPALFTQMAALAAMWRSFGIA 183 + + P LL+ DD S Q LF +L + +S+G+ Sbjct: 566 ACALLDRELGVEPP--LLEVLSADDESPAGKLLEQTMYAQCGLFALEVSLFRLLQSWGLE 623 Query: 184 PNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDL 243 P +GHS GE+ AA+V+ ++LE+A ++G R +RE E Sbjct: 624 PTWLLGHSIGELVAAHVADVLSLEEACTLVGARARLMQALPATGAMYTVQASEREVLE-A 682 Query: 244 LARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGA 303 LA A ++ NSP ISG+ + VQ + +RV + H+ + DG Sbjct: 683 LAGHGERAAVAASNSPTSTVISGDLQVVQQVAAAFEARERKTARLRVSHAFHSHHM-DGM 741 Query: 304 DKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAV 363 + + L++ + + TL P +EL YW +R VRF + Sbjct: 742 LAEFGRVAEGLRYRAPRIAIVSTATGTLAQP--AELCSPQYWVQQVRATVRFGDGLQTLQ 799 Query: 364 QRDVETFVELAEHPTLQLAIHENLAALRDEA--DDRPAMVVGTSERTATDLGEFTRNLAQ 421 Q TF+EL H L AL EA D + T R ++ L Sbjct: 800 QEGARTFLELGPHGV--------LTALGQEALPDAEGLAFLPTLRRARSESATTAEALGG 851 Query: 422 LAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLP 468 LA + WE + +P Q + L P R W+ P Sbjct: 852 LARRGYSPDWESV-FKPYRPQKIAL---PTYAFQRERYWVDASAARP 894 >tr|D0LQW1|D0LQW1_HALO1 Tax_Id=502025 SubName: Full=6-deoxyerythronolide-B synthase; EC=2.3.1.94;[Haliangium ochraceum] Length = 1867 Score = 164 bits (415), Expect = 6e-38 Identities = 130/438 (29%), Positives = 185/438 (42%), Gaps = 27/438 (6%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 AA P +P LLS T E L ++A L H+ H D +S L Sbjct: 471 AAATAPVAALPFLLSGKTEEALKAQAQRLHQHLQRHEDAALVDVSYSLATTRAHFEQRAA 530 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 TR EL+ AL A+ + P+L+ P + ++ +VF S Sbjct: 531 LVASTREELLAALAALANGESAPSLV-VAPRSADGKVVFVFPGQGSQWQGMGRALLRSSD 589 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAG---IVQPALFTQMAALAAMWRSF 180 AFRAEV+ C AF GS R L + GS+ ++QP LFT M +LAA WRS Sbjct: 590 AFRAEVEACEAAFAPYIDGSLREAL------EGGSSDRVDVLQPVLFTMMVSLAAHWRSL 643 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ +GHSQGEVAAAYV+G ++L+DA +++ +R E Sbjct: 644 GVVAAAVVGHSQGEVAAAYVAGALSLDDAAQIVALR-SRALRRVAGRGAMAAVELGAEQL 702 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 LA + VNSPR ++G+ + +++ L E G + + R + +H L+ Sbjct: 703 ATYLAPFEEQLAIGAVNSPRASLVAGQPAALDALLEKLAEDGVYTQKARGNHASHCRLVE 762 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 A +L A+Q PS I G + DYW+ NLR V F A Sbjct: 763 PLAQELTDALQG--IRPS--TCAIPLYSTVTGTRLEGHELDADYWYQNLRAPVLFQSATE 818 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVV-------GTSERTATDLG 413 + + FVEL+ HP L L ++E +A + A VV GT R LG Sbjct: 819 RLLADGHDLFVELSPHPVLSLPLYETF-----DAREHSAQVVTSLRRGDGTHARMLLSLG 873 Query: 414 EFTRNLAQLAVHDLNYPW 431 E +L H PW Sbjct: 874 ELHNRGHKLDWHAFFAPW 891 Score = 110 bits (276), Expect = 8e-22 Identities = 119/440 (27%), Positives = 169/440 (38%), Gaps = 53/440 (12%) Query: 601 VTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAAL 660 +T G AA + PD VHA RS EHP V +D ++ ++ Sbjct: 1326 LTQGSVAAHGEETLPDLVHAPLWGLLRSAQTEHPQVALSLIDTDDHDASRS---KLLELF 1382 Query: 661 HTANEP-------ELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLEF 711 + EP +L RDG A R+ VL+ G TG LG Sbjct: 1383 DSTAEPTVECDKAQLILRDGNVLAPRLVRVTTRPDDDTRSFDPDSTVLVTGATGTLGTLL 1442 Query: 712 CDHF-AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAA-- 768 H AH G + + LVSR G++A A L + + A++ + CD D A+ L Sbjct: 1443 ARHLVAHHGVKHLLLVSRQGQAATGAGALIKDLESAGAEVTIAACDSADRRALETLLGSV 1502 Query: 769 --QHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVL 826 QH P +IH A + D + AKV + + D VL Sbjct: 1503 PPQH---PLRAVIHVAGVVEDATVERLAPDRLRRVMRAKVDAALNLHELTQGLDLTTFVL 1559 Query: 827 CSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW------TVHFDLDAS 880 SS +G GQ YAAAN LD +A +A GL +++ WG W T H L + Sbjct: 1560 FSSFSGLLGSAGQANYAAANTFLDGLAQHRKARGLPALAIAWGFWSDRSAQTAH--LGDA 1617 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQR-LGRNAIVAAFDFD-----RARPVLETFGYGPLVS 934 + + A G+ + +AL Q L R A ++A D R R L T + + Sbjct: 1618 DLQRFAQRGLRALSAEAGLALFDQALLRREAALSAVRLDRDVLARRRDSLPTLLRSLVPN 1677 Query: 935 ELLSPVSETAAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSV----------------PM 978 +L S+ P+ A LP RL + V P+ Sbjct: 1678 KLARAASD---PSAQASLPRRLRELAPEDGDRVLLDLVRSEVAAVLGISSPSSLEPQRPL 1734 Query: 979 VALGLDSLQALELRRRVKAE 998 LG DSL ALE+R R+ A+ Sbjct: 1735 QELGTDSLMALEIRNRLSAK 1754 >tr|D0LQW0|D0LQW0_HALO1 Tax_Id=502025 SubName: Full=Acyl transferase;[Haliangium ochraceum] Length = 3449 Score = 164 bits (415), Expect = 6e-38 Identities = 130/438 (29%), Positives = 185/438 (42%), Gaps = 27/438 (6%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 AA P +P LLS T E L ++A L H+ H D +S L Sbjct: 482 AAATAPVAALPFLLSGKTEEALKAQAQRLHQHLQRHEDAALVDVSYSLATTRAHFEQRAA 541 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 TR EL+ AL A+ + P+L+ P + ++ +VF S Sbjct: 542 LVASTREELLAALAALANGESAPSLV-VAPRSADGKVVFVFPGQGSQWQGMGRALLRSSD 600 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAG---IVQPALFTQMAALAAMWRSF 180 AFRAEV+ C AF GS R L + GS+ ++QP LFT M +LAA WRS Sbjct: 601 AFRAEVEACEAAFAPYIDGSLREAL------EGGSSDRVDVLQPVLFTMMVSLAAHWRSL 654 Query: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETC 240 G+ +GHSQGEVAAAYV+G ++L+DA +++ +R E Sbjct: 655 GVVAAAVVGHSQGEVAAAYVAGALSLDDAAQIVALR-SRALRRVAGRGAMAAVELGAEQL 713 Query: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 LA + VNSPR ++G+ + +++ L E G + + R + +H L+ Sbjct: 714 ATYLAPFEEQLAIGAVNSPRASLVAGQPAALDALLEKLAEDGVYTQKARGNHASHCRLVE 773 Query: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 A +L A+Q PS I G + DYW+ NLR V F A Sbjct: 774 PLAQELTDALQG--IRPS--TCAIPLYSTVTGTRLEGHELDADYWYQNLRAPVLFQSATE 829 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVV-------GTSERTATDLG 413 + + FVEL+ HP L L ++E +A + A VV GT R LG Sbjct: 830 RLLADGHDLFVELSPHPVLSLPLYETF-----DAREHSAQVVTSLRRGDGTHARMLLSLG 884 Query: 414 EFTRNLAQLAVHDLNYPW 431 E +L H PW Sbjct: 885 ELHNRGHKLDWHAFFAPW 902 Score = 146 bits (369), Expect = 1e-32 Identities = 129/454 (28%), Positives = 192/454 (42%), Gaps = 21/454 (4%) Query: 14 PVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAELI 73 P +LS + L ++ LR ++AAHPDL+ ++ L R LI Sbjct: 2050 PFVLSGKSEPALRAQVEQLRAYLAAHPDLSLSDLAYSLATTRSHFDHRVAIVASDRTALI 2109 Query: 74 DALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRCA 133 L A + PA ++ +VF S FRA+V+ C Sbjct: 2110 HQL-AELGAGRAPADTLLGRRGADGKLTFVFPGQGSQWIGMAASLLTSSAVFRAQVEACE 2168 Query: 134 QAFEAQSCGSPRNYLLDKNFQDDGSA----GIVQPALFTQMAALAAMWRSFGIAPNVTIG 189 AF S L D + ++QPALFT M +LAA+WR+ G+ P+ +G Sbjct: 2169 HAFSPYIDWSLLALLQAGPGDPDAARLDQIDVLQPALFTVMVSLAALWRAMGVEPDAVVG 2228 Query: 190 HSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCSG 249 HSQGEVAAA+V+G ++L+ A R++ +R R E LLA + Sbjct: 2229 HSQGEVAAAHVAGILSLDVAARIVAVR-SRALGAFTGRGSMAAVELPRGELEQLLATSAL 2287 Query: 250 WAQLSV--VNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLR 307 +LSV VNSP ++G E + ++ L G FA +R +H I D+L Sbjct: 2288 GERLSVAAVNSPCSTALAGAAEDIDELLQLLATEGIFALKLRADVASHCDQIEPLRDQLL 2347 Query: 308 AAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDV 367 + + + P+ + G L P EL YWF NLR V F A + Sbjct: 2348 SELGEFDPQPAQIPFYSTVTGKRLAGP---ELNAA-YWFDNLRQPVLFGDATQLLLADGH 2403 Query: 368 ETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHDL 427 FVE++ HP L +IHE L +A+++ A VVG+ + L F ++ +L Sbjct: 2404 RFFVEVSPHPVLAFSIHETL-----DAEEQTACVVGSLWQEEGYLARFLLSMVELHGGGF 2458 Query: 428 NYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 W +P A+ +PL P R R WL Sbjct: 2459 PVDWRTF-FQPTMARPVPL---PTYRFQHERFWL 2488 Score = 130 bits (327), Expect = 9e-28 Identities = 129/446 (28%), Positives = 184/446 (41%), Gaps = 52/446 (11%) Query: 591 VDTGV-TDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATA 649 +D G+ + WL+T G + A+ +P+ A R +G EHP +DLP A + Sbjct: 1109 LDAGLKSSVWLLTRGAVSIGPAERLTNPLQAMTWGTGRVLGLEHPDYWGGLIDLPE-ACS 1167 Query: 650 QDWAHPIVAALHTANEPE-LAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGN 706 +V L +E + LA R +YA+R+ VLI GGTG Sbjct: 1168 DGAVERLVGLLGACSEEDQLALRGPGWYARRLVRAPLGAAEAADTYVPRGTVLITGGTGG 1227 Query: 707 LGLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRL 766 LG A +GA+ + LVSR GE + AE+L S A++ + CDV D AA+ +L Sbjct: 1228 LGAHVARWLASKGAQHLVLVSRRGELSPGAEQLHDELSELGARVTIAACDVADRAALHKL 1287 Query: 767 AAQHRSTPADL--IIHAA--------VAYASVEFSDITTDDADNALYAKVVGIGQVLDAF 816 + A + ++HA +A EF+++ + A A + Q LDAF Sbjct: 1288 LDALDAEGASIRSVVHAGGVAQQTPLIAMTLREFAEVVSGKARGAQFLHERFDAQPLDAF 1347 Query: 817 PRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT---V 873 VL SS ++ GG GQ YAA N LDA+A R G SV WG W + Sbjct: 1348 --------VLFSSGSSSWGGGGQGAYAAGNAFLDALAEHRRGLGRAATSVAWGAWAGDGM 1399 Query: 874 HFDLDASSMAQLAAIGVIPMPPAEAIALGMQRLGRNAI---VAAFDFDRARPVLETFGYG 930 LD S + L G++PM P AIA Q L VA D+ R P + Sbjct: 1400 VTLLDDSGESALRTRGILPMSPELAIAALAQALDHRETKLTVANMDWARFAPAFASARSR 1459 Query: 931 PLV-----------------------SELLSPVSETAAPAEPADLPGRLSNXXXXXXXXX 967 PL+ +ELL+ + + P L R+ Sbjct: 1460 PLLHDLAEAKGALEGAEGTSALEGRETELLAHLRKLTEPDRRRLLLSRVLEETAAVLGHA 1519 Query: 968 XXXXXDTSVPMVALGLDSLQALELRR 993 + +GLDSL ALELR+ Sbjct: 1520 DASRVEAKRGFFEMGLDSLLALELRK 1545 Score = 114 bits (285), Expect = 7e-23 Identities = 125/452 (27%), Positives = 175/452 (38%), Gaps = 51/452 (11%) Query: 588 WPGVDTGVTDCWLVTVGGEAATAADGPPDPVHAAASAGF-RSIGAEHPGVGFRHLDLPAG 646 W + T +V G AT D + A+ G R +EHP +D+ Sbjct: 2892 WLAEERFATARLIVVTRGAIATRPDEDVLGLAQASLWGLVRVAQSEHPDASLTLVDVD-- 2949 Query: 647 ATAQDWAHPIVAALHT-------ANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH-- 697 +D H + + A EP+LA R G R+ Sbjct: 2950 -NREDSLHALFGLFGSRTAPNALAAEPQLAVRAGNVSVPRLARLTEAPDAHARPFDPAGT 3008 Query: 698 VLIIGGTGNLGLEFCDHFAHR-GARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCD 756 +LI GGTG LG H + GAR + L SR G +A A L + A+ V CD Sbjct: 3009 LLITGGTGTLGRLLARHVVTKHGARHLLLASRQGLAAPGASELVSDLAEAGAEATVVACD 3068 Query: 757 VGDPAAVSRL-AAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDA 815 V D +A+ RL AA + P ++H A +T D L K+ + + Sbjct: 3069 VSDRSALQRLVAAVPANHPLTGVLHLAGVLDDAVIESLTPKHFDTVLRVKLDAAYHLHEL 3128 Query: 816 FPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW---- 871 D V+ SS +G GQ YAAAN LDA+AH +A+G +++ WG W Sbjct: 3129 TLEHDLAAFVMFSSLSGVLGSAGQANYAAANTFLDALAHHRKAQGRHGLAIDWGYWEDRS 3188 Query: 872 --TVHFDLDASSMAQLAAIGVIPMPPAEAIALGMQRLGR-NAIVAAFDFDR--------- 919 T H L A+ + + A G+ P+ E +AL L R +A++ A D Sbjct: 3189 ALTAH--LTAADLQRFARSGLRPLSAQEGLALFDAALTRPDAVLVAVRLDAMALAKHANA 3246 Query: 920 -------------ARPVLET-FGYGPLVSELLSPVSETAAPAEPADLPGRLSNXXXXXXX 965 ARP+ T L L S V E APA L + + Sbjct: 3247 LPPLLSGLVPAKVARPMASTGTSVASLQQRLASLVVEERAPA----LLEIVCSEVATVLG 3302 Query: 966 XXXXXXXDTSVPMVALGLDSLQALELRRRVKA 997 D P+ LGLDSL ALE+R R+ A Sbjct: 3303 LASPNALDPERPLQELGLDSLMALEIRNRLSA 3334 >tr|B6ZK65|B6ZK65_9ACTO Tax_Id=324833 (lsd12)SubName: Full=Putative polyketide synthase;[Streptomyces lasaliensis] Length = 5429 Score = 162 bits (411), Expect = 2e-37 Identities = 125/466 (26%), Positives = 192/466 (41%), Gaps = 42/466 (9%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHP--DLTPGPISAMLFXXXXXXXXXXXXXXXT 68 G +P L+S T E L +A LR V + +L P ++ L Sbjct: 2191 GALPWLVSGRTAEALREQAARLRSFVQSDEAVELEPSAVAGALAAERATFGHRAVVLGSD 2250 Query: 69 RAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 R + DAL A+ + HP +++ + R + +VF +S P F A Sbjct: 2251 RPDFTDALTALAEGTPHPGVVQATALEVTRTV-FVFPGQGSQWTGMGRELLDSSPEFAAY 2309 Query: 129 VDRCAQAFEAQSCGSPRNYLLDKNFQD-----DGSAG-----IVQPALFTQMAALAAMWR 178 + C A N +D + D +G+ G +VQPALF M +LA +W+ Sbjct: 2310 IAECETAL---------NDFVDWSLTDVLRGTEGAPGYDRVDVVQPALFAVMVSLARLWQ 2360 Query: 179 SFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRE 238 GI P+ IGHSQGE+AAA+++G +TL DA R++ +R + Sbjct: 2361 HHGIHPDAVIGHSQGEIAAAHIAGALTLNDAARIVALRSQALLPLAGLGGMTSLALPHHQ 2420 Query: 239 TCEDLLARCSGWAQ---LSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAH 295 E + W Q ++ VN P +SG + + T G AR I V Y +H Sbjct: 2421 AHELI----QPWGQDLSIASVNGPHSTVVSGTTHALDELHTTCNTQGVRARRIPVDYASH 2476 Query: 296 TSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRF 355 ++ + D + A P T + G PI DYW+ NLR+ VRF Sbjct: 2477 SAQVESIRDTVLQAATGINPQP----TAVPLYSTVTGQPINGTQLDADYWYTNLRHTVRF 2532 Query: 356 DKAIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEF 415 ++ + A + D F+E HP L +A+ E + A+ +R A+VVGT R + F Sbjct: 2533 EETVRALLGDDHNAFIEATAHPVLTMAVEETVGAV-----EREAVVVGTLRRDEGGIDRF 2587 Query: 416 TRNLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 +LA V + W + G + +D P R WL Sbjct: 2588 RTSLAMAWVRGVGVDWVGML----GGRGARPVDLPTYAFQRERYWL 2629 Score = 122 bits (305), Expect = 3e-25 Identities = 105/334 (31%), Positives = 145/334 (43%), Gaps = 28/334 (8%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAA 659 +VT G A +G D AA RS +E+PG R L L + + A V Sbjct: 1274 VVTRGAVAVLPGEGVDDLAQAALWGLVRSAQSENPG---RFLLLDSDTDVPEEA---VRR 1327 Query: 660 LHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--------VLIIGGTGNLGLEF 711 L + + + A R+GA R+ VL+ GGTG LG Sbjct: 1328 LAASGDEQAALREGALLTPRLARASVPSGTEAESSAAGAPFSSEGTVLVTGGTGTLGGLV 1387 Query: 712 CDHF-AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQH 770 H A G R + L+SR G A A LA +A+ A++ CD D A++ + A Sbjct: 1388 ARHLVAEHGVRHLLLLSRQGADAPGAGGLADELAASGARVTFAACDASDREALAGVLA-- 1445 Query: 771 RSTPADL----IIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVL 826 S PAD ++HAA A + + +T + + L K + + D VL Sbjct: 1446 -SVPADRPLTGVVHAAGALSDATVAALTPEHLERVLRPKADAAAHLDELTRDLDLSAFVL 1504 Query: 827 CSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW----TVHFDLDASSM 882 SSA +G GQ YAAAN LDA+A R RA+GL VSV WG W + L Sbjct: 1505 FSSAAGVLGNPGQANYAAANTFLDALAERRRAQGLPAVSVAWGLWAPSSAMRAHLGERDE 1564 Query: 883 AQLAAIGVIPMPPAEAIAL--GMQRLGRNAIVAA 914 A++ GV+PMP + +AL R R +VAA Sbjct: 1565 ARIVGSGVLPMPAEQGLALLDAALRADRPLVVAA 1598 Score = 119 bits (299), Expect = 2e-24 Identities = 93/376 (24%), Positives = 149/376 (39%), Gaps = 7/376 (1%) Query: 10 DGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTR 69 D T+P++LS TPE L ++A L H+ P+L ++A L R Sbjct: 4258 DSTMPLVLSGHTPEALRTQADRLHAHLTGRPELPVAQVAASLVATRAALDHRGAVLAEDR 4317 Query: 70 AELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEV 129 ++ L A+ P ++ T R + +VF ++ P F + Sbjct: 4318 EGFLEGLHALAQGRPSPQVV-TATTENRGKTVFVFPGQGSQWPGMGRELLDTSPVFATHI 4376 Query: 130 DRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNVTIG 189 C A S + L D I+QP LF M +LA +W+ GI P+ G Sbjct: 4377 TECEAALTPYVDWSLTDVLRQGEPLD--RIEILQPVLFALMVSLARLWQHHGIHPDAVTG 4434 Query: 190 HSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCSG 249 HSQGE+AAA+++G +TL+DA R++ +R L + G Sbjct: 4435 HSQGEIAAAHIAGALTLDDATRIVVLRSQLFADHLTGHGAIASLTLPATQVTHQLTQYDG 4494 Query: 250 WAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLRAA 309 ++ +NSP ++G + + + G AR+I +H+ + D L Sbjct: 4495 RLTIAGINSPTTCTVAGPHTDLTTLTHWARQQGARARIIDTTVASHSPHVEPLHDDLIHL 4554 Query: 310 IQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDVET 369 + D P T I T PI +YW+ N R+ VRF + Sbjct: 4555 LADITPQPG--TTPIYSTVTT--EPIDGTQLTAEYWYDNCRHPVRFHDTLHTLTTHGHTH 4610 Query: 370 FVELAEHPTLQLAIHE 385 ++E++ HP L AI E Sbjct: 4611 YLEISPHPVLIPAITE 4626 Score = 115 bits (287), Expect = 4e-23 Identities = 120/440 (27%), Positives = 176/440 (40%), Gaps = 35/440 (7%) Query: 592 DTGV-TDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPA--GAT 648 D GV W VT G + +A + A A G R + E P +DLP G Sbjct: 4871 DAGVDAPLWCVTSGAVSVSATEYALPEQAAVAGLG-RVVALEQPQRWGGTIDLPGQLGDV 4929 Query: 649 AQDWAHPIVAAL-HTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTG 705 A +V L +E +LA R + +R+ VL+ GGTG Sbjct: 4930 DDQVAVRLVGVLAEHGDEDQLAVRASGVFGRRLVRAPLGAAAPVRSWKPRGTVLVTGGTG 4989 Query: 706 NLGLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR 765 +G A GA + LVSRSG A A L +A+ A+++V CDV D AV R Sbjct: 4990 GVGGRVARWLATSGAEHLLLVSRSGPEAPGAAELEADLAASGARVSVVACDVADRDAVER 5049 Query: 766 -LAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRI 824 L++ + P ++HAA ++T + + L AKV+G + + Sbjct: 5050 LLSSVPDAHPLTAVVHAAGVPQQSAVEELTPAEVEEILSAKVLGARHLDELLADAPLDAF 5109 Query: 825 VLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDA-SSMA 883 VL SS G G YAAAN LDA+A R RA G SV WG W + A + A Sbjct: 5110 VLFSSNAGVWGSGGHSAYAAANAYLDALAERRRAHGRTATSVAWGAWAAGGMMAAEGAAA 5169 Query: 884 QLAAIGVIPMPPAEAIALGMQRLGRN---AIVAAFDFDRARPVLETFGYGPLVSE----- 935 + GV+ M P A+A + + + VA D++R + PL+ + Sbjct: 5170 YMGRRGVLDMEPERAVAALVAAVEHDETFVAVAHMDWERFVLGFTSLRPSPLLDDIPEAR 5229 Query: 936 --LLSPVSETAAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSVPMV-------------- 979 L ET + ++ + L L++ ++ V Sbjct: 5230 RALAELAEETESGSDASTLARELADMSPDDRRAALLDLVQSNAAAVLGHTGGAAVDAHRA 5289 Query: 980 --ALGLDSLQALELRRRVKA 997 LG DSL A++LR R+ A Sbjct: 5290 FKELGFDSLTAVQLRNRLNA 5309 Score = 113 bits (282), Expect = 2e-22 Identities = 102/332 (30%), Positives = 134/332 (40%), Gaps = 39/332 (11%) Query: 698 VLIIGGTGNLGLEFCDHFAH-RGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCD 756 VLI GGTG LG H G RR+ L SR G +A A LA A + + CD Sbjct: 3443 VLITGGTGTLGALTARHLVTTHGTRRLLLTSRQGMAAPGAAPLADELRDLGAHVTIAACD 3502 Query: 757 VGDPAAVSRLA----AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQV 812 D A++ L A+H P +IH A A +T + + L KV + Sbjct: 3503 TADRTALTHLLDSIPAEH---PLTAVIHCAGALDDGTVPTLTPERFEAVLRPKVDAAWNL 3559 Query: 813 LDAFPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW- 871 D D VL SSA +GG GQ YA AN LDA+AH A GL S+ WG W Sbjct: 3560 HDLTRHLDLSAFVLFSSAAGVLGGAGQANYATANTFLDALAHHRHAHGLPATSLTWGHWE 3619 Query: 872 -----TVHFDLDASSMAQLAAIGVIPMPPAEAIAL---GMQRLGRNAIVAAFDFDRARPV 923 T H LD + +A++ G++PM PA +AL ++ + D R Sbjct: 3620 QASGMTGH--LDRTDLARIGRTGLLPMSPAYGLALFDAALRESDAVLVPVRLDTGALREQ 3677 Query: 924 LETFGYGPLVSELL-SPVSETAAPAEPAD-------LPGRLSNXXXXXXXXXXXXXXDTS 975 P+ EL+ P TAA AD L GR + T Sbjct: 3678 HAGGALPPVFRELVRGPARRTAATGGAADQSALARTLAGRSTTEQKAILLDLVRTHIATV 3737 Query: 976 V------------PMVALGLDSLQALELRRRV 995 + P LG DSL ++ELR R+ Sbjct: 3738 LGHTTPDTINPDQPFKDLGFDSLTSVELRNRL 3769 Score = 104 bits (260), Expect = 6e-20 Identities = 87/378 (23%), Positives = 144/378 (38%), Gaps = 13/378 (3%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRA 70 G + +LS T + L ++A+ L + P L + A L R Sbjct: 436 GPVSWVLSGKTAQALRAQASQLHSLAESEPALDAHAVEAALATTRAALEHRAVVLSEDRE 495 Query: 71 ELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVD 130 L++ L A+ P ++ T R + +VF ++ P F + Sbjct: 496 GLVEGLHALAQGRPSPQVV-TATTENRGKTVFVFPGQGSQWPGMGRELLDTSPVFATHIT 554 Query: 131 RCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNVTIGH 190 C A S + L ++ + I+QP LF M +LA +W+ GI P+ GH Sbjct: 555 ECEAALTPYVDWSLTDVL--RHGEPLDRIEILQPVLFALMVSLARLWQHHGIHPDAVTGH 612 Query: 191 SQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCSGW 250 SQGE+AAA+++G +TL+DA R++ +R L + G Sbjct: 613 SQGEIAAAHIAGALTLDDATRIVVLRSQLFADHLTGHGAIASLTLPATQVTHQLPQYDGR 672 Query: 251 AQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIR---VRYPAHTSLIHDGADKLR 307 ++ +NSP ++G + + + G AR+I + H +HD L Sbjct: 673 LTIAGINSPTTCTVAGPHTDLTTLTHWARQQGARARIIDTTVASHSPHVEPLHDQLLHLL 732 Query: 308 AAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDV 367 A I Q + PI +YW+ N R+ VRF + Sbjct: 733 ADISPQA-------ASVPIYSTVTTEPIDGTQLTAEYWYDNCRHPVRFHDTLHTLTTHGH 785 Query: 368 ETFVELAEHPTLQLAIHE 385 ++E++ HP L AI E Sbjct: 786 THYLEISPHPVLIPAITE 803 >tr|B5M9K9|B5M9K9_9ACTO Tax_Id=324833 (lasAII)SubName: Full=Lasalocid modular polyketide synthase;[Streptomyces lasaliensis] Length = 5469 Score = 162 bits (411), Expect = 2e-37 Identities = 125/466 (26%), Positives = 192/466 (41%), Gaps = 42/466 (9%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHP--DLTPGPISAMLFXXXXXXXXXXXXXXXT 68 G +P L+S T E L +A LR V + +L P ++ L Sbjct: 2231 GALPWLVSGRTAEALREQAARLRSFVQSDEAVELEPSAVAGALAAERATFGHRAVVLGSD 2290 Query: 69 RAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 R + DAL A+ + HP +++ + R + +VF +S P F A Sbjct: 2291 RPDFTDALTALAEGTPHPGVVQATALEVTRTV-FVFPGQGSQWTGMGRELLDSSPEFAAY 2349 Query: 129 VDRCAQAFEAQSCGSPRNYLLDKNFQD-----DGSAG-----IVQPALFTQMAALAAMWR 178 + C A N +D + D +G+ G +VQPALF M +LA +W+ Sbjct: 2350 IAECETAL---------NDFVDWSLTDVLRGTEGAPGYDRVDVVQPALFAVMVSLARLWQ 2400 Query: 179 SFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRE 238 GI P+ IGHSQGE+AAA+++G +TL DA R++ +R + Sbjct: 2401 HHGIHPDAVIGHSQGEIAAAHIAGALTLNDAARIVALRSQALLPLAGLGGMTSLALPHHQ 2460 Query: 239 TCEDLLARCSGWAQ---LSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAH 295 E + W Q ++ VN P +SG + + T G AR I V Y +H Sbjct: 2461 AHELI----QPWGQDLSIASVNGPHSTVVSGTTHALDELHTTCNTQGVRARRIPVDYASH 2516 Query: 296 TSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRF 355 ++ + D + A P T + G PI DYW+ NLR+ VRF Sbjct: 2517 SAQVESIRDTVLQAATGINPQP----TAVPLYSTVTGQPINGTQLDADYWYTNLRHTVRF 2572 Query: 356 DKAIAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEF 415 ++ + A + D F+E HP L +A+ E + A+ +R A+VVGT R + F Sbjct: 2573 EETVRALLGDDHNAFIEATAHPVLTMAVEETVGAV-----EREAVVVGTLRRDEGGIDRF 2627 Query: 416 TRNLAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 +LA V + W + G + +D P R WL Sbjct: 2628 RTSLAMAWVRGVGVDWVGML----GGRGARPVDLPTYAFQRERYWL 2669 Score = 122 bits (305), Expect = 3e-25 Identities = 105/334 (31%), Positives = 145/334 (43%), Gaps = 28/334 (8%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAA 659 +VT G A +G D AA RS +E+PG R L L + + A V Sbjct: 1314 VVTRGAVAVLPGEGVDDLAQAALWGLVRSAQSENPG---RFLLLDSDTDVPEEA---VRR 1367 Query: 660 LHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--------VLIIGGTGNLGLEF 711 L + + + A R+GA R+ VL+ GGTG LG Sbjct: 1368 LAASGDEQAALREGALLTPRLARASVPSGTEAESSAAGAPFSSEGTVLVTGGTGTLGGLV 1427 Query: 712 CDHF-AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQH 770 H A G R + L+SR G A A LA +A+ A++ CD D A++ + A Sbjct: 1428 ARHLVAEHGVRHLLLLSRQGADAPGAGGLADELAASGARVTFAACDASDREALAGVLA-- 1485 Query: 771 RSTPADL----IIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVL 826 S PAD ++HAA A + + +T + + L K + + D VL Sbjct: 1486 -SVPADRPLTGVVHAAGALSDATVAALTPEHLERVLRPKADAAAHLDELTRDLDLSAFVL 1544 Query: 827 CSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW----TVHFDLDASSM 882 SSA +G GQ YAAAN LDA+A R RA+GL VSV WG W + L Sbjct: 1545 FSSAAGVLGNPGQANYAAANTFLDALAERRRAQGLPAVSVAWGLWAPSSAMRAHLGERDE 1604 Query: 883 AQLAAIGVIPMPPAEAIAL--GMQRLGRNAIVAA 914 A++ GV+PMP + +AL R R +VAA Sbjct: 1605 ARIVGSGVLPMPAEQGLALLDAALRADRPLVVAA 1638 Score = 119 bits (299), Expect = 2e-24 Identities = 93/376 (24%), Positives = 149/376 (39%), Gaps = 7/376 (1%) Query: 10 DGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTR 69 D T+P++LS TPE L ++A L H+ P+L ++A L R Sbjct: 4298 DSTMPLVLSGHTPEALRTQADRLHAHLTGRPELPVAQVAASLVATRAALDHRGAVLAEDR 4357 Query: 70 AELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEV 129 ++ L A+ P ++ T R + +VF ++ P F + Sbjct: 4358 EGFLEGLHALAQGRPSPQVV-TATTENRGKTVFVFPGQGSQWPGMGRELLDTSPVFATHI 4416 Query: 130 DRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNVTIG 189 C A S + L D I+QP LF M +LA +W+ GI P+ G Sbjct: 4417 TECEAALTPYVDWSLTDVLRQGEPLD--RIEILQPVLFALMVSLARLWQHHGIHPDAVTG 4474 Query: 190 HSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCSG 249 HSQGE+AAA+++G +TL+DA R++ +R L + G Sbjct: 4475 HSQGEIAAAHIAGALTLDDATRIVVLRSQLFADHLTGHGAIASLTLPATQVTHQLTQYDG 4534 Query: 250 WAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLRAA 309 ++ +NSP ++G + + + G AR+I +H+ + D L Sbjct: 4535 RLTIAGINSPTTCTVAGPHTDLTTLTHWARQQGARARIIDTTVASHSPHVEPLHDDLIHL 4594 Query: 310 IQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDVET 369 + D P T I T PI +YW+ N R+ VRF + Sbjct: 4595 LADITPQPG--TTPIYSTVTT--EPIDGTQLTAEYWYDNCRHPVRFHDTLHTLTTHGHTH 4650 Query: 370 FVELAEHPTLQLAIHE 385 ++E++ HP L AI E Sbjct: 4651 YLEISPHPVLIPAITE 4666 Score = 115 bits (287), Expect = 4e-23 Identities = 120/440 (27%), Positives = 176/440 (40%), Gaps = 35/440 (7%) Query: 592 DTGV-TDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPA--GAT 648 D GV W VT G + +A + A A G R + E P +DLP G Sbjct: 4911 DAGVDAPLWCVTSGAVSVSATEYALPEQAAVAGLG-RVVALEQPQRWGGTIDLPGQLGDV 4969 Query: 649 AQDWAHPIVAAL-HTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTG 705 A +V L +E +LA R + +R+ VL+ GGTG Sbjct: 4970 DDQVAVRLVGVLAEHGDEDQLAVRASGVFGRRLVRAPLGAAAPVRSWKPRGTVLVTGGTG 5029 Query: 706 NLGLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR 765 +G A GA + LVSRSG A A L +A+ A+++V CDV D AV R Sbjct: 5030 GVGGRVARWLATSGAEHLLLVSRSGPEAPGAAELEADLAASGARVSVVACDVADRDAVER 5089 Query: 766 -LAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRI 824 L++ + P ++HAA ++T + + L AKV+G + + Sbjct: 5090 LLSSVPDAHPLTAVVHAAGVPQQSAVEELTPAEVEEILSAKVLGARHLDELLADAPLDAF 5149 Query: 825 VLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDA-SSMA 883 VL SS G G YAAAN LDA+A R RA G SV WG W + A + A Sbjct: 5150 VLFSSNAGVWGSGGHSAYAAANAYLDALAERRRAHGRTATSVAWGAWAAGGMMAAEGAAA 5209 Query: 884 QLAAIGVIPMPPAEAIALGMQRLGRN---AIVAAFDFDRARPVLETFGYGPLVSE----- 935 + GV+ M P A+A + + + VA D++R + PL+ + Sbjct: 5210 YMGRRGVLDMEPERAVAALVAAVEHDETFVAVAHMDWERFVLGFTSLRPSPLLDDIPEAR 5269 Query: 936 --LLSPVSETAAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSVPMV-------------- 979 L ET + ++ + L L++ ++ V Sbjct: 5270 RALAELAEETESGSDASTLARELADMSPDDRRAALLDLVQSNAAAVLGHTGGAAVDAHRA 5329 Query: 980 --ALGLDSLQALELRRRVKA 997 LG DSL A++LR R+ A Sbjct: 5330 FKELGFDSLTAVQLRNRLNA 5349 Score = 113 bits (282), Expect = 2e-22 Identities = 102/332 (30%), Positives = 134/332 (40%), Gaps = 39/332 (11%) Query: 698 VLIIGGTGNLGLEFCDHFAH-RGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCD 756 VLI GGTG LG H G RR+ L SR G +A A LA A + + CD Sbjct: 3483 VLITGGTGTLGALTARHLVTTHGTRRLLLTSRQGMAAPGAAPLADELRDLGAHVTIAACD 3542 Query: 757 VGDPAAVSRLA----AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQV 812 D A++ L A+H P +IH A A +T + + L KV + Sbjct: 3543 TADRTALTHLLDSIPAEH---PLTAVIHCAGALDDGTVPTLTPERFEAVLRPKVDAAWNL 3599 Query: 813 LDAFPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW- 871 D D VL SSA +GG GQ YA AN LDA+AH A GL S+ WG W Sbjct: 3600 HDLTRHLDLSAFVLFSSAAGVLGGAGQANYATANTFLDALAHHRHAHGLPATSLTWGHWE 3659 Query: 872 -----TVHFDLDASSMAQLAAIGVIPMPPAEAIAL---GMQRLGRNAIVAAFDFDRARPV 923 T H LD + +A++ G++PM PA +AL ++ + D R Sbjct: 3660 QASGMTGH--LDRTDLARIGRTGLLPMSPAYGLALFDAALRESDAVLVPVRLDTGALREQ 3717 Query: 924 LETFGYGPLVSELL-SPVSETAAPAEPAD-------LPGRLSNXXXXXXXXXXXXXXDTS 975 P+ EL+ P TAA AD L GR + T Sbjct: 3718 HAGGALPPVFRELVRGPARRTAATGGAADQSALARTLAGRSTTEQKAILLDLVRTHIATV 3777 Query: 976 V------------PMVALGLDSLQALELRRRV 995 + P LG DSL ++ELR R+ Sbjct: 3778 LGHTTPDTINPDQPFKDLGFDSLTSVELRNRL 3809 Score = 104 bits (260), Expect = 6e-20 Identities = 87/378 (23%), Positives = 144/378 (38%), Gaps = 13/378 (3%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRA 70 G + +LS T + L ++A+ L + P L + A L R Sbjct: 476 GPVSWVLSGKTAQALRAQASQLHSLAESEPALDAHAVEAALATTRAALEHRAVVLSEDRE 535 Query: 71 ELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVD 130 L++ L A+ P ++ T R + +VF ++ P F + Sbjct: 536 GLVEGLHALAQGRPSPQVV-TATTENRGKTVFVFPGQGSQWPGMGRELLDTSPVFATHIT 594 Query: 131 RCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNVTIGH 190 C A S + L ++ + I+QP LF M +LA +W+ GI P+ GH Sbjct: 595 ECEAALTPYVDWSLTDVL--RHGEPLDRIEILQPVLFALMVSLARLWQHHGIHPDAVTGH 652 Query: 191 SQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCSGW 250 SQGE+AAA+++G +TL+DA R++ +R L + G Sbjct: 653 SQGEIAAAHIAGALTLDDATRIVVLRSQLFADHLTGHGAIASLTLPATQVTHQLPQYDGR 712 Query: 251 AQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIR---VRYPAHTSLIHDGADKLR 307 ++ +NSP ++G + + + G AR+I + H +HD L Sbjct: 713 LTIAGINSPTTCTVAGPHTDLTTLTHWARQQGARARIIDTTVASHSPHVEPLHDQLLHLL 772 Query: 308 AAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDV 367 A I Q + PI +YW+ N R+ VRF + Sbjct: 773 ADISPQA-------ASVPIYSTVTTEPIDGTQLTAEYWYDNCRHPVRFHDTLHTLTTHGH 825 Query: 368 ETFVELAEHPTLQLAIHE 385 ++E++ HP L AI E Sbjct: 826 THYLEISPHPVLIPAITE 843 >tr|Q30CS2|Q30CS2_STRAU Tax_Id=1894 (lipPks1)SubName: Full=LipPks1;[Streptomyces aureofaciens] Length = 2259 Score = 161 bits (408), Expect = 4e-37 Identities = 120/442 (27%), Positives = 182/442 (41%), Gaps = 10/442 (2%) Query: 12 TIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAE 71 T+P +LSA +P+ L ++A LR HVA P L ++ L R E Sbjct: 1088 TVPWVLSAASPDALRAQAERLRGHVAERPGLASADVAFALATRRTALEYRAVAVGAERDE 1147 Query: 72 LIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDR 131 L+D L A+ P + D AA RR +VF +S P F + Sbjct: 1148 LLDTLDALSAGRPAPRAVPGDAAAHSRRPVFVFPGQGSQWAGMAVELLDSSPVFADSMHA 1207 Query: 132 CAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNVTIGHS 191 C++A + L + + +VQP L+ M +LAA+W++ G+ P +GHS Sbjct: 1208 CSEALNEFVDWNLLEVLRSGDEELSNRVDVVQPVLWAVMVSLAALWQACGVRPAAVVGHS 1267 Query: 192 QGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCSGWA 251 QGE+AAA V+G ++L D RV+ +R +T + L G Sbjct: 1268 QGEIAAAVVAGALSLRDGARVVALRSAVIARLLAGKGAMASVALASDTVRERLTPWEGRL 1327 Query: 252 QLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLRAAIQ 311 L+ VN P + G + + V L G R I V Y +H+ + ++LR + Sbjct: 1328 SLAAVNGPSSSVVCGHLDALDEFVSALEHDGVRVRRIAVDYASHSVFVEQAEEELRNVLT 1387 Query: 312 DQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDVETFV 371 + P V GA L T+ L G YW+ NLR VRF++ + +R + F+ Sbjct: 1388 EVSPLPGQVPFYSTVTGAVLD---TTTLDAG-YWYRNLRQTVRFEETVRELTRRGHDAFI 1443 Query: 372 ELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHDLNYPW 431 E++ HP L + I + L EA V GT R +L + V + W Sbjct: 1444 EVSAHPVLTVGIQDTL-----EATGTRHAVCGTLRRGEGGAQRLLTSLGEAWVAGIAVDW 1498 Query: 432 ECLRAEPDGAQALPLLDFPNTR 453 L Q LP F + R Sbjct: 1499 SRLTPTTTAVQ-LPTYAFQHQR 1519 Score = 125 bits (314), Expect = 3e-26 Identities = 121/421 (28%), Positives = 178/421 (42%), Gaps = 23/421 (5%) Query: 13 IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXT--RA 70 +P +L+ + + + ALR H+ A + +P + L RA Sbjct: 80 LPWVLTGPGAAAVRARSEALRTHLRASTEWSPAGVGQALLAGTGAGADTHRAVVLAGDRA 139 Query: 71 ELIDALQAMIDRYEHPALIRTDPA-AIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEV 129 + ++AL A+ +HPA+ + A A +VF +S P F ++ Sbjct: 140 QTLNALAALSAGADHPAVFTSTRADASPAGPVFVFPGQGSQWTGMARELLDSAPVFARKL 199 Query: 130 DRCAQAFEAQSCGSPRNYLLDKNFQDDGS-----AGIVQPALFTQMAALAAMWRSFGIAP 184 CA AF S LLD G A +VQPALF M AL +W + G+AP Sbjct: 200 HDCADAFAPYLGHS----LLDSVTGAAGGPEPVGADVVQPALFAVMVALTDLWNAAGVAP 255 Query: 185 NVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLL 244 +GHS GE+AAA+V+G ++L+D+ RV+ E + L Sbjct: 256 GALLGHSLGELAAAHVAGVLSLDDSARVVARWSQAQATLAGRGDMVSVLLPADELADLLD 315 Query: 245 ARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGAD 304 R G ++V N P SG+ + +V LT G AR + V AH+ I Sbjct: 316 RRWPGRLVVAVENGPGSAVASGDLDAAAELVAHLTAEGIHARRVDVGLAAHSPHIDAILP 375 Query: 305 KLRAAIQDQLQH-PSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAV 363 ++RA I H PS GA G P+ + YW NLR+ VRF A AA+ Sbjct: 376 RIRADIAPIRAHTPSIPVYSALHGGALDGTPMDAA-----YWCRNLRSTVRFADATRAAL 430 Query: 364 QRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLA 423 + TFVE++ HP L A+ ++A R A V+GT R F +LA+L Sbjct: 431 EAGHTTFVEVSPHPVLTTAM--EVSATRAA---HAATVLGTLRRGEGGPSRFLASLAELH 485 Query: 424 V 424 V Sbjct: 486 V 486 Score = 89.0 bits (219), Expect = 3e-15 Identities = 120/440 (27%), Positives = 163/440 (37%), Gaps = 50/440 (11%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVA 658 W+VT AA P P+ + + EH +DLP A+ A + A Sbjct: 1712 WMVTREAVAAGQDTHPHAPLGSLIWGLGQVTALEHADRWGGLIDLPGVCDARV-ARMLCA 1770 Query: 659 ALHTAN-EPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLEFCDHF 715 L E +LA R + +R+ V++ GGTG LG Sbjct: 1771 GLSGRGAEDQLALRPSGTFVRRLAHIPGEQRAARRSWQPRGTVIVTGGTGALGAVLARWL 1830 Query: 716 AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVS----RLAAQHR 771 A A + L R G A AERL AT A++ + CDV D AV+ LAA Sbjct: 1831 ATEDAEHLVLTGRRGADAPGAERLRDELVATGARVTLAACDVADRKAVAALLDELAADGE 1890 Query: 772 STPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSAR 831 + A ++HAA + + + AKV G + + VL SS Sbjct: 1891 TVRA--VLHAAGVADLTSLENTGPEAFAAGVAAKVDGALHLTELLDHDSLDAFVLFSSIA 1948 Query: 832 ATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDL-------DASSMAQ 884 G YAAAN L+A+A RA G+ S+ WG W F + +A + Q Sbjct: 1949 GVWGSGDHGAYAAANAFLNALAEYNRARGIPTTSIAWGVWNA-FGVEGAGGISEAVDLDQ 2007 Query: 885 LAAIGVIPMPPAEAIALGMQRLGRNAIVAA------------FDFDRARPVLETFGYGPL 932 L G+ + P + + L R+ V F R RP+ E P Sbjct: 2008 LHRRGLPLIEPELGLTALRRALDRDETVLTVAPVAWERFFPLFSAARPRPLFEDL---PQ 2064 Query: 933 VSELLSPVSETAAPA-EP-------ADLP------GRLSNXXXXXXXXXXXXXXDTSVPM 978 V L +PV TA PA EP DLP L+ D P Sbjct: 2065 VRALSAPVPTTAGPAVEPGRRGSGLGDLPLTDRDSALLALVRGESASVLGYERPDRLDPD 2124 Query: 979 VAL---GLDSLQALELRRRV 995 AL G DSL A+ELR R+ Sbjct: 2125 RALRDVGFDSLTAMELRNRL 2144 >tr|Q93HJ2|Q93HJ2_STRAW Tax_Id=33903 (olmA6)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 4685 Score = 160 bits (406), Expect = 7e-37 Identities = 133/468 (28%), Positives = 196/468 (41%), Gaps = 31/468 (6%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRA 70 G +P L+S T L ++A L +H+A P+ TP + L R Sbjct: 476 GPVPWLVSGRTEAALRAQAARLAEHLAGRPEATPLDVGFSLARTRSAFEQRAVVVSADRD 535 Query: 71 ELIDALQAMIDRYEHPAL--IRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 ELI L+++ D + + + A + +VF +S P FRA Sbjct: 536 ELIAGLRSVADSGDGAGVAGVVAGRATADSGVVFVFPGQGSQWVGMAAELLDSAPVFRAR 595 Query: 129 VDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAMWRSFGIA 183 ++ C +A S LL Q++G+ +VQP L+ M +LAA+WRSFG+ Sbjct: 596 MEECGEALAPHVDWS----LLAVVRQEEGTPSWSRVDVVQPVLWAVMVSLAAVWRSFGVE 651 Query: 184 PNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDL 243 P +GHSQGEVAAA V+G ++LED RV+ +R E+ Sbjct: 652 PAAVVGHSQGEVAAACVAGGLSLEDGARVVAVRSRLVLEKLSGKGGMVSVALPVGEVEER 711 Query: 244 LARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHD-G 302 LAR G ++ VN P V +SGE + + ++ E G AR I V Y +H++ + Sbjct: 712 LARFEGRIGVAAVNGPGSVVVSGEPDALDELLAECEESGVRARRIAVDYASHSAQVDALN 771 Query: 303 ADKLR--AAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 D LR A IQ + +F T G + + YW NLR VRF+ + Sbjct: 772 EDLLRELADIQPRSSSVAFYST-------VTGERLDTSGLDARYWVTNLRERVRFEPVVR 824 Query: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 ++ FVE + HP L +A+ E E DR + VG+ R F +LA Sbjct: 825 LLAEKGSSVFVESSPHPVLTMAVAET-----GEVADRAVVTVGSLRRDDGGADRFLTSLA 879 Query: 421 QLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLP 468 + V W L A + +D P R WL D LP Sbjct: 880 EAYVAGAPVDWSVLFA----GMPVRRVDLPTYAFQHQRYWLD-DVALP 922 Score = 150 bits (378), Expect = 1e-33 Identities = 133/462 (28%), Positives = 190/462 (41%), Gaps = 36/462 (7%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRA 70 G +P L+S T L ++A L +H+A P+ P + L T Sbjct: 2008 GPVPWLVSGRTEAALRAQAARLAEHLAGRPEAAPLDVGFSLATTRANLEHRAVVLGSTSE 2067 Query: 71 ELIDALQAMIDRYEHPALIR---TDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRA 127 EL L A+ + PA+IR TD + +VF ++ P F Sbjct: 2068 ELTRGLNAVAEAAISPAVIRGNGTDTGVV-----FVFPGQGSQWVGMGRDLWDVSPVFAE 2122 Query: 128 EVDRCAQAFEAQSCGSPRNYLLDKNFQDDGS-----AGIVQPALFTQMAALAAMWRSFGI 182 + C +A S R+ + F+D G +VQP L+ M +LAA+WRSFG+ Sbjct: 2123 SMVACERALSPLVDWSLRDVV----FRDAGDPLWSRVDVVQPVLWAVMVSLAAVWRSFGV 2178 Query: 183 APNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCED 242 P +GHSQGEVAAA V+G ++LED RV+ +R E E+ Sbjct: 2179 EPAAVVGHSQGEVAAACVAGGLSLEDGARVVAVRSRLVLEKLSGKGGMVSVALPVEGVEE 2238 Query: 243 LLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDG 302 LAR G ++ VN P V +SGE E + ++ G AR I V Y +H++ + Sbjct: 2239 RLARFEGRIGVAAVNGPTSVVVSGEPEALDELLAECEGSGVRARRIAVDYASHSAQVDAL 2298 Query: 303 ADKL---RAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAI 359 D L A I+ + +F T T G TS L YW NLR VRF+ + Sbjct: 2299 NDDLLAELAGIRPKSSTVAFYST------VTGGRLDTSGLD-ARYWVTNLRERVRFEPVV 2351 Query: 360 AAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNL 419 + FVE + HP L +A+ E E DR + VG+ R +L Sbjct: 2352 RLLADQAHGLFVEASPHPVLNMAVAET-----GEVADRAVVTVGSLRRDDGGADRLLTSL 2406 Query: 420 AQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 A+ V W L A G + + L P R WL Sbjct: 2407 AEAHVAGAPVDWSVLFA-GTGTRRIGL---PTYAFQHQRYWL 2444 Score = 142 bits (358), Expect = 2e-31 Identities = 129/463 (27%), Positives = 187/463 (40%), Gaps = 23/463 (4%) Query: 4 AAYRLPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXX 63 AA L +P + S + L +A L V P L ++ L Sbjct: 3520 AAPALVTPVVPWVFSGRSSGALCGQAGRLGGLVEREPGLDVTDVAFSLATTRANLEHRAV 3579 Query: 64 XXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVP 123 A L+D L+++ R E A + + A R+ +VF ++ P Sbjct: 3580 VLGGDAAGLLDRLRSVAAR-EPDAGVVSGTTAAGGRVVFVFPGQGSQWVGMGRDLWDVSP 3638 Query: 124 AFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGS-----AGIVQPALFTQMAALAAMWR 178 F + C +A S R+ + F+D G +VQP L+ M +LAA+WR Sbjct: 3639 VFAESMVACERALSPLVDWSLRDVV----FRDAGDPLWSRVDVVQPVLWAVMVSLAAVWR 3694 Query: 179 SFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRE 238 SFG+ P +GHSQGEVAAA V+G ++LED RV+ +R E Sbjct: 3695 SFGVDPAAVVGHSQGEVAAACVAGGLSLEDGARVVAVRSRLVLEKLSGKGGMVSVALPVE 3754 Query: 239 TCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSL 298 E+ LAR G ++ VN P V +SGE + + ++ E G AR I V Y +H++ Sbjct: 3755 GVEERLARFEGRIGVAAVNGPTSVVVSGEPDALDELLAECEESGVRARRIAVDYASHSAQ 3814 Query: 299 IHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKA 358 + D L A + D S V G L TS L YW NLR VRF+ Sbjct: 3815 VDALNDDLLAELADIRPKSSTVAFYSTVTGDRLD---TSGLD-ARYWVTNLRERVRFEPV 3870 Query: 359 IAAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRN 418 + ++ FVE + HP L +A+ E E DR + VG+ R + Sbjct: 3871 VRLLAEKGSSVFVESSPHPVLTMAVAET-----GEVADRAVVTVGSLRRDDGGADRLLTS 3925 Query: 419 LAQLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 LA+ V W L A + +D P R WL Sbjct: 3926 LAEAYVAGAPVDWSVLFAGTGARR----VDLPTYAFQHQRYWL 3964 Score = 120 bits (301), Expect = 1e-24 Identities = 128/418 (30%), Positives = 171/418 (40%), Gaps = 44/418 (10%) Query: 551 GTGADVNTLVILLPETPK----LDGRAA-AAEVGGFFSNRAWWPGV-------------D 592 G GA+V V+L ET + L GR A A E+ G S W D Sbjct: 2551 GAGAEV---VVLAWETEEGREALAGRLAEAGELSGVVSLLGWDEKAAPAATVTLVQGLAD 2607 Query: 593 TGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPA---GATA 649 GV V G A+ + PV A + +G E PG +D+P A Sbjct: 2608 AGVEAPLWVLTHGAASVGSGDVIRPVQTQVWALGQIVGLEQPGSWGGLVDVPEVWDERVA 2667 Query: 650 QDWAHPIVAALHTANEPELAYRDGAFYAKR-IXXXXXXXXXXXXXCPEH--VLIIGGTGN 706 +A + A E ++A R YA+R + H VLI GGTG Sbjct: 2668 SGFAGVLAAG---EGEDQVAVRSSGAYARRLVRAPLGANPAPVRDWNPHGTVLITGGTGG 2724 Query: 707 LGLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRL 766 +G A GA R+ LVSRSGE A A LA A++ CDV D A++ + Sbjct: 2725 IGAHLARWLAKEGAERLLLVSRSGERAEGAAELAAELGGLGAEVTFAACDVTDRDALAHV 2784 Query: 767 AAQHRSTPADLIIHAA--VAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRI 824 A+H P + H A +Y +V D+ D D + AK +G + LD G + Sbjct: 2785 IAEH---PPTAVFHTAGVASYGTVRELDLA--DLDAQMAAKTLG-ARHLDELTTERGLEL 2838 Query: 825 ---VLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASS 881 V+ SS A G G YAAAN LD +A RA GL SV WG W + Sbjct: 2839 DAFVVFSSGAAIWGSAGNGGYAAANAYLDGLAWDRRARGLAATSVSWGGWKATGMATDDT 2898 Query: 882 MAQLAAIGVIPMPPAEAIALGMQRLGRN---AIVAAFDFDRARPVLETFGYGPLVSEL 936 QLA GV PM PA A+ Q L ++ V D++R P PL+ ++ Sbjct: 2899 AEQLARRGVRPMDPARAVEALRQALEQDETALTVTDMDWERFTPGYTMARRRPLIEDI 2956 Score = 105 bits (261), Expect = 4e-20 Identities = 121/442 (27%), Positives = 168/442 (38%), Gaps = 43/442 (9%) Query: 592 DTGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQD 651 D GV V G A+ A+ PV A + G E PG +D+P G + Sbjct: 1080 DAGVEAPLWVLTQGAASVGAEDVVHPVQTQVWALGQVAGLEQPGSWGGLVDVP-GVWDER 1138 Query: 652 WAHPIVAALHTAN-EPELAYRDGAFYAKR-IXXXXXXXXXXXXXCPEH--VLIIGGTGNL 707 A + A L E ++A R YA+R + H VLI GGTG + Sbjct: 1139 VASGLTAVLAAGEGEDQVAVRSSGAYARRLVRAPLGANPAPVRDWNPHGTVLITGGTGGI 1198 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR-L 766 G A GA R+ LVSRSGE A A LA A++ CDV D A++ + Sbjct: 1199 GAHLARWLAKEGAERLLLVSRSGEQAEGAAELATELGGLGAEVTFAACDVSDRDALAHVI 1258 Query: 767 AAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRI-- 824 A P + H A E + T + + L A+V+G + LD G + Sbjct: 1259 AGIPAEHPLTAVFHTAGISGYAELATATPEHFTDVLSARVLG-ARHLDELTAELGVELEA 1317 Query: 825 -VLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMA 883 V+ SS A G AAA LD + R RA G+ SV WG W + Sbjct: 1318 FVVFSSGAAVWGSGSNGANAAAGGYLDGLVRRRRARGVAGTSVSWGGWQATAMAVGDTAE 1377 Query: 884 QLAAIGVIPMPPAEAIALGMQRLGRNAI-VAAFDFD-----------RARPVLETF---- 927 QL+ GV + P A+ Q L ++ + V D D R RP++E Sbjct: 1378 QLSRRGVRLLDPVLAVQALRQVLEQDEVSVTVTDMDWALFTPGYAMARRRPLIEDIPEAG 1437 Query: 928 --------------GYGPLVSELLSPVSETAAPAEPADLPGRLSNXXXXXXXXXXXXXXD 973 G + E L+ ++ET A L G + Sbjct: 1438 EALSGAAGAGETLDSAGVGLRERLAAMTET---ERQATLLGLVRGEAAQVLAHGSTAEIT 1494 Query: 974 TSVPMVALGLDSLQALELRRRV 995 + P LG DSL A++LR R+ Sbjct: 1495 PTRPFKELGFDSLTAMDLRNRL 1516 Score = 100 bits (249), Expect = 1e-18 Identities = 117/441 (26%), Positives = 166/441 (37%), Gaps = 54/441 (12%) Query: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPI-- 656 W+VT G + + D PV A + +G E PG +D+P + W + Sbjct: 4143 WVVTRGAASVDSGD-EIRPVQTQVWALGQIVGLEQPGSWGGLVDVP-----EVWDERVAS 4196 Query: 657 -VAALHTANEPE--LAYRDGAFYAKR-IXXXXXXXXXXXXXCPEH--VLIIGGTGNLGLE 710 VA + A E E +A R YA+R + H VLI GGTG +G Sbjct: 4197 QVAGVLAAGEGEDQVAVRSSGAYARRLVRAPLGANPAPVRDWNPHGTVLITGGTGGIGAH 4256 Query: 711 FCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR----L 766 A GA R+ LVSRSGE A A LA A++ CDV D A++ + Sbjct: 4257 LARWLAKEGAERLLLVSRSGERAEGAAELAAELGGLGAEVTFAACDVTDRDALAHVIAGI 4316 Query: 767 AAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRI-- 824 A+H P + H A +D+ D D A++ G + LD G + Sbjct: 4317 PAEH---PLTAVFHTAGVAGHGPLADLDVTDLDTQTAARIAG-ARHLDELTAELGVELEA 4372 Query: 825 -VLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMA 883 V+ SS A G AAA LD + RA G+ SV WG W + Sbjct: 4373 FVVFSSGAAVWGSGSNGANAAAGGYLDGLVRLRRARGVAGTSVSWGGWQATAMAVGDTAE 4432 Query: 884 QLAAIGVIPMPPAEAIALGMQRLGRNAI-VAAFDFD-----------RARPVLETFGYGP 931 QL+ GV + P A+ Q L ++ + V D D R RP++E Sbjct: 4433 QLSRRGVRLLDPVLAVQALRQALEQDEVSVTVTDMDWALFTPGYAMARRRPLIEDIPEAA 4492 Query: 932 LV-----------------SELLSPVSETAAPAEPADLPGRLSNXXXXXXXXXXXXXXDT 974 V ++L ++ P A L G + Sbjct: 4493 QVLRDAEEIEDGPEDGAAGADLRKRLAGLTDPERQATLLGLVRGEAAQVLAHGSTAEITP 4552 Query: 975 SVPMVALGLDSLQALELRRRV 995 + P LG DSL A++LR R+ Sbjct: 4553 TRPFKELGFDSLTAMDLRNRL 4573 >tr|Q93HJ1|Q93HJ1_STRAW Tax_Id=33903 (olmA7)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 3613 Score = 160 bits (406), Expect = 7e-37 Identities = 136/465 (29%), Positives = 194/465 (41%), Gaps = 27/465 (5%) Query: 12 TIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAE 71 T+P L+S T L ++A L+ H+ AHP L ++ L A Sbjct: 482 TVPWLISGQTEAALRAQAGRLQAHLDAHPGLGTADVAHSLLASRSKLAHRAVLFAGQGAR 541 Query: 72 LID---ALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 D L A+ D + P L+R A + +VF +++ P FRA Sbjct: 542 SGDRPTGLTALADGLDVPGLVRGTGDA-GTGVVFVFPGQGSQWVGMGRDLWDASPVFRAR 600 Query: 129 VDRCAQAFEAQSCGSPRNYLLDKNFQDDGS-----AGIVQPALFTQMAALAAMWRSFGIA 183 ++ C QA S RN + F+D G +VQP L+ M +LAA+WRSFG+ Sbjct: 601 MEECGQALSPYVDWSLRNVV----FRDAGDPLWSRVDVVQPVLWAVMVSLAAVWRSFGVE 656 Query: 184 PNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDL 243 P +GHSQGEVAAA V+G ++LED RV+ +R E E+ Sbjct: 657 PAAVVGHSQGEVAAACVAGGLSLEDGARVVAVRSRLVLEKLSGKGGMVSVALPVEGVEER 716 Query: 244 LARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGA 303 LAR G ++ VN P +SGE + + ++ E G AR I V Y +H++ + Sbjct: 717 LARFEGRIGVAAVNGPGSAVVSGEPDALDELLAECEESGVRARRIAVDYASHSAQVDALN 776 Query: 304 DKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAV 363 D L A + D S V G L TS L YW NLR VRF+ + Sbjct: 777 DDLLAELADIRPKSSAVAFYSTVTGERLD---TSGLD-ARYWVTNLRERVRFEPVVRLLA 832 Query: 364 QRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLA 423 +++ + FVE + HP L +AI E E VG+ R F +LA+ Sbjct: 833 EQEYQVFVESSPHPVLTVAIQET-----QEGVFGTGTAVGSLRRDEGGADRFLTSLAEAY 887 Query: 424 VHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLP 468 V W L A + +D P R W+ D V P Sbjct: 888 VAGAPVDWSVLFA----GMPVRRVDLPTYAFQHERYWIE-DVVAP 927 Score = 118 bits (296), Expect = 4e-24 Identities = 133/442 (30%), Positives = 170/442 (38%), Gaps = 46/442 (10%) Query: 592 DTGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQD 651 D GV V G A+ A+ PV A + G E PG +D+P G + Sbjct: 1084 DAGVEAPLWVLTQGAASVGAEDVVHPVQTQVWALGQVAGLEQPGSWGGLVDVP-GVWDER 1142 Query: 652 WAHPIVAALHTAN-EPELAYRDGAFYAKR-IXXXXXXXXXXXXXCPEH--VLIIGGTGNL 707 A + A L E ++A R YA+R + H VLI GGTG + Sbjct: 1143 VASGLTAVLAAGEGEDQVAVRSSGAYARRLVRAPLGANPAPVRDWNPHGTVLITGGTGGI 1202 Query: 708 GLEFCDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAA----V 763 G A GA R+ LVSRSGE A A LA A++ CDV D A + Sbjct: 1203 GAHLARWLAKEGAERLLLVSRSGEQAEGAAELATELGGLGAEVTFAACDVSDRDALGHVI 1262 Query: 764 SRLAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCR 823 + + A+H P + H A E + T + + L AK G + LDA Sbjct: 1263 AGIPAEH---PLTAVFHTAGVSGYAELATATPEHYETVLSAKTRG-ARNLDALTAELTLE 1318 Query: 824 -IVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSM 882 VL SS A G G YAAAN LD +A RA GL SV WG W + Sbjct: 1319 AFVLFSSGAAVWGSAGTGAYAAANAYLDGLAWNRRARGLVATSVSWGGWKATGMAADGTE 1378 Query: 883 AQLAAIGVIPMPPAEAIALGMQRLGRN-AIVAAFDFD-----------RARPVLETFGYG 930 QLA GV M PA AI Q L ++ + D D R RP++E Sbjct: 1379 EQLARRGVRAMEPALAIKALRQALEQDETALTVTDMDWARFTPGYTIARRRPLIEDI--- 1435 Query: 931 PLVSELLSPVSETA-----------------APAEPADLPGRLSNXXXXXXXXXXXXXXD 973 P V+ LS SE A AP + L + + Sbjct: 1436 PEVARALSEDSEPAPDDGTDSALRQTLAGLTAPEQHDRLLELVRSEAATVLTHRTTDDIT 1495 Query: 974 TSVPMVALGLDSLQALELRRRV 995 P LG DSL A+ELR R+ Sbjct: 1496 AGRPFRDLGFDSLTAMELRNRL 1517 Score = 99.0 bits (245), Expect = 3e-18 Identities = 126/432 (29%), Positives = 166/432 (38%), Gaps = 48/432 (11%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPG--VGFRHLDLPAGATAQDWAHPIV 657 L+T G A D D +A R+ +EHP V D PA A + Sbjct: 2848 LLTRGAVPAAGTDRTEDVAASAVWGLVRTAQSEHPDRIVLIDLDDDPASYRA------LP 2901 Query: 658 AALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH-VLIIGGTGNLGLEFCDHF- 715 AL T EP+LA R G+ R+ P+ VL+ GGTG LG H Sbjct: 2902 KALGTG-EPQLALRAGSPCVPRLARHTGPADGAPGFGPDGTVLVTGGTGALGAVVARHLV 2960 Query: 716 -AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTP 774 AH G R + L R GE A A L + A + CDV D A LA R P Sbjct: 2961 TAH-GVRHLVLAGRRGERAPGAAALLAELTELGADTRILACDVSDRDA---LAVLLRDIP 3016 Query: 775 AD----LIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSA 830 AD ++H A A +T D D L AK + + VL SSA Sbjct: 3017 ADRPLTAVVHTAGVLADGTVESLTPDRFDTVLRAKADAAWHLHELTQDAPLREFVLFSSA 3076 Query: 831 RATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLA 886 +G +GQ YAAAN LDA+A R GL ++ WG W + DL + A++A Sbjct: 3077 AGLLGSQGQGNYAAANSFLDALAAHRREAGLPGTALAWGWWEQPGGMGGDLGRAERARMA 3136 Query: 887 AIGVIPMPPAEAI-----ALGM--------QRLGRNAIVAAFDFDRARPVLETFGYGPLV 933 GV P + ALG RL A AA + + P+L P Sbjct: 3137 RGGVTPFTAESGMEAFDRALGAGQEALLVPMRLNTTAARAASE-QQVPPLLRGLVRAPQR 3195 Query: 934 SELLSPVSETA------APAEPADLPGRLSNXXXXXXXXXXXXXXDTSVP----MVALGL 983 S V T+ A A+ A+ L+ ++ V LG Sbjct: 3196 RAARSDVRATSHLHEQLAAADQAERQALLAELIRGEVAQVLGHSGAEAIEDGHGFVELGF 3255 Query: 984 DSLQALELRRRV 995 DSL ++ELR R+ Sbjct: 3256 DSLTSVELRNRL 3267 Score = 97.4 bits (241), Expect = 9e-18 Identities = 95/384 (24%), Positives = 148/384 (38%), Gaps = 31/384 (8%) Query: 13 IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAEL 72 +P ++SA + E L ++A L DHV DL P + L R + Sbjct: 2005 VPWVVSARSEEALRAQARRLADHVRGS-DLRPADVGLSLAVTRAGLEHRAVLTGRDREDF 2063 Query: 73 IDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDR- 131 + L A+ + ++R A ++F YE P F A D Sbjct: 2064 LVQLAALAEGAGAAGMVRG--VAGEGGTAFLFTGQGAQRLGMGRELYERFPVFAAAFDGV 2121 Query: 132 CAQAFEAQSCGSPRNYLLDKNFQD----DGSA----GIVQPALFTQMAALAAMWRSFGIA 183 CAQ + LL++ ++ D A Q LF AL + S+G+ Sbjct: 2122 CAQL----------DLLLERPVKEVVFTDAPALDRTVFTQAGLFALEVALFELVGSWGVR 2171 Query: 184 PNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDL 243 +V +GHS GE+AAAYV+G +L DA R++ R E ED Sbjct: 2172 ADVLLGHSIGELAAAYVAGVWSLADACRIVAARGRLMQALPEGGAMVAV-----EAAEDE 2226 Query: 244 LARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGA 303 L G ++ VN PR + +SG+ E V + E G + + V + H++ + Sbjct: 2227 LPVLPGGVSVAAVNGPRSLVLSGDEEPVTALAQAFAEQGRRTKQLAVSHAFHSARM---- 2282 Query: 304 DKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAV 363 + + A + L F I + G +E YW ++R VRF +A + Sbjct: 2283 EPMLAEFAETLAAVEFRPPRIPVVSNVTGGMADAEFTTPAYWVRHVREAVRFADGVATVL 2342 Query: 364 QRDVETFVELAEHPTLQLAIHENL 387 R V+ F+EL L E L Sbjct: 2343 ARGVDRFLELGPRGALTAMAEETL 2366 >tr|Q1L0T0|Q1L0T0_STRHY Tax_Id=285527 SubName: Full=GelC;[Streptomyces hygroscopicus subsp. duamyceticus] Length = 3888 Score = 160 bits (406), Expect = 7e-37 Identities = 129/452 (28%), Positives = 187/452 (41%), Gaps = 30/452 (6%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRA 70 GT P +LSA TP L ++A L DH+ + D P I L T A Sbjct: 2570 GTTPWVLSAKTPAALRAQARRLLDHLESDVDAHPVDIGWSLATTRTLHDHRAVVITDTEA 2629 Query: 71 ---ELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRA 127 E AL A+ HP L T A + +VF ++ P F Sbjct: 2630 DSDEAAAALTALATGQPHPRLT-TGHATTHGKTAFVFPGQGAQWVGMGAQLLKTSPVFAE 2688 Query: 128 EVDRCAQAFEAQS--------CGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRS 179 + CA A + G+P L++ +VQPA F + +LAA+W+S Sbjct: 2689 RLHECAAALAPYTGWSLIDVITGTPDAPSLER-------VDVVQPATFAVVVSLAALWQS 2741 Query: 180 FGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRET 239 GI P+ IGHSQGE+AAA V+G +TL +A +++ +R RE Sbjct: 2742 VGIHPDAVIGHSQGEIAAACVAGHLTLTNAAKIVTLRSQTIAAHLAGHGGMMSVLASREQ 2801 Query: 240 CEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLI 299 E+ L G ++ NSP I+G+ + + + T+ G AR+I V Y +HT + Sbjct: 2802 VEEALTPWHGKLWIAAHNSPNATVIAGDTDALHQLHTHYTDQGIRARIIPVDYASHTGHV 2861 Query: 300 HDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAI 359 ++L + D P I L G I + YW+ NLR V+F AI Sbjct: 2862 DTIKNQLHQTLADTTTEPG----TIPWLSTVTGQWIEPDTVDSGYWYRNLRQTVQFHTAI 2917 Query: 360 AAAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRP-AMVVGTSERTATDLGEFTRN 418 A TF+E++ HP L AI E L EA+D P + GT R F + Sbjct: 2918 TALAHEGYRTFIEISPHPVLTTAIQETL-----EANDTPNTTITGTLRRDDDTPTRFLTH 2972 Query: 419 LAQLAVHDLNYPWECLRAEPDGAQALPLLDFP 450 LA+L+ W +Q +PL +P Sbjct: 2973 LAELSTRGTPMDWPTAYTGSQPSQ-IPLPTYP 3003 Score = 124 bits (311), Expect = 7e-26 Identities = 125/445 (28%), Positives = 171/445 (38%), Gaps = 39/445 (8%) Query: 585 RAWWPGVDTGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLP 644 R W + T ++T G AA DP AA RS +EHPG R +D+ Sbjct: 3397 RQWVDRRELADTHLVVLTHGAMAAHDTAEVTDPAAAAVWGLVRSAQSEHPG-RIRLIDI- 3454 Query: 645 AGATAQDWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH-VLIIGG 703 D +H + E +LA RD Y + PE VLI GG Sbjct: 3455 -----DDHSHQALPTALATTEAQLALRDATAYTPHLTPAPATTPEPLTLDPEGTVLITGG 3509 Query: 704 TGNLGLEFCDHF-AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAA 762 TG LG H H AR + LVSR G A A LA + A + + CD D Sbjct: 3510 TGTLGALTARHLITHHHARHLLLVSRQGPDAPGATDLATELTELGAHVRIAACDTADRGQ 3569 Query: 763 VSRLAAQHRST-PADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDG 821 ++ L A + P ++H A +D+T D KV + + D D Sbjct: 3570 LAALLADIPADHPLTAVVHTAGTLDDALLTDLTPQRLDTVFRPKVDALTHLHDLTRDHDL 3629 Query: 822 CRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASS 881 V+ SSA T+G GQ YAAAN DA+AH+ A GL S+ WG W L A Sbjct: 3630 TAFVIYSSATGTLGTPGQANYAAANTYADALAHQRHAAGLPATSLAWGLWETTSSLTAGM 3689 Query: 882 MA----QLAAIGVIPMPPAEAIALGMQRLG-RNAIVAAFDFDRAR-----------PVLE 925 A + GV+P+ A+ + L L R+ + + D A P+L Sbjct: 3690 TATQQQRTRDSGVVPLTDADGMRLLDTALATRHPHLVPLELDLAALQNNTGPHTLPPLLR 3749 Query: 926 TFGYG---PLVSELLSP------VSETAAPAEPADLPGRLSNXXXXXXXXXXXXXXDTSV 976 T G P P ++E A +P RL+ +V Sbjct: 3750 TLIRGHHRPTAHTTAQPEDDAPSLAEQLAALDPTQRHQRLTALVRAEAAAVLGHPTPDAV 3809 Query: 977 ----PMVALGLDSLQALELRRRVKA 997 + +G DSL A+ELR R+ A Sbjct: 3810 GPDDALFEIGFDSLTAVELRNRLNA 3834 Score = 102 bits (254), Expect = 3e-19 Identities = 115/441 (26%), Positives = 162/441 (36%), Gaps = 55/441 (12%) Query: 629 IGAEHPGVGFRHLDLPAGATAQ---DWAHPIVAALHTANEPELAYRDG----AFYAKRIX 681 +GA HP V +R DL A A+ + H +V L R A A R Sbjct: 1660 VGARHPEVTYRAFDLGGEAPAERVRELLHQLVELFEAGRIEPLPVRQWDITRAPEAFRWM 1719 Query: 682 XXXXXXXXXXXXCPEH------VLIIGGTGNLGLEFCDHF-AHRGARRITLVSRSGESAA 734 P VL+ GGTG LG H GAR + LVSR G A Sbjct: 1720 SQGRHTGKIVLTLPRALDPDGTVLVTGGTGTLGATIARHLLTQHGARHLLLVSRRGPDAP 1779 Query: 735 VAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHRST-PADLIIHAAVAYASVEFSDI 793 A L + A + +T CD D ++ L A + P ++H A + + Sbjct: 1780 GATDLTTELTELGATVRITACDTADRGQLAALLADIPADHPLTAVVHTAGTLDDGILTAL 1839 Query: 794 TTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMA 853 T D D KV + + D D V+ SSA +GG GQ Y+AAN LD +A Sbjct: 1840 TPDRLDTVFRPKVDAVTHLHDLTRDHDLAAFVVYSSAAGVLGGPGQGNYSAANAYLDGLA 1899 Query: 854 HRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLAAIGVIPMPPAEAIALGMQRLGRN 909 RA GL S+ WG W + L + + ++ G++ + AEA+ L + + Sbjct: 1900 QWRRAHGLPATSLAWGMWAQTSGMTAGLGSGDLHRVRRGGIVGLSTAEALDLFDRSVASG 1959 Query: 910 -AIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPAEPA---DLPGRLSNXXXXXXX 965 ++ D A E PL+ L+ P TA P A L RL+ Sbjct: 1960 LPLLVPLRLDIAALGAEAAEPPPLLRGLVRPARRTARPVPKAGEGGLAERLAGLSAAEQE 2019 Query: 966 XXXXXXXDTSVPMVA----------------LGLDSLQALELRRRVKAE----------F 999 V +G DSL A+ELR R+ F Sbjct: 2020 RLLIELIREQAASVLGFPTVDPIGPEQAFRDMGFDSLTAVELRNRLNTATGLRLPATLVF 2079 Query: 1000 DHELEVS------DLLGGASI 1014 DH ++ D LGG ++ Sbjct: 2080 DHPSPLATAEFLRDQLGGRAV 2100 Score = 89.7 bits (221), Expect = 2e-15 Identities = 107/459 (23%), Positives = 164/459 (35%), Gaps = 29/459 (6%) Query: 13 IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAEL 72 +P LLS T E L ++A L V P +P + L + Sbjct: 496 VPWLLSGHTQEALRAQAARLLTQVRETPSDSPRDVGWSLATTRTRLDHRAVVLCADAEQA 555 Query: 73 IDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDRC 132 + L+A+ + + A+ ++ +F + P F D Sbjct: 556 VAGLEAVASGTSARSAVTGSVAS--GKVAVLFTGQGSQRAGMGRELHGGHPVFARAFDAV 613 Query: 133 AQAFEAQSCGSPRNYLLDKNFQDDGSAG--------IVQPALFTQMAALAAMWRSFGIAP 184 F G + L + F ++GSA QPALF AL + S+G+ P Sbjct: 614 CAQFGDLRDGDDKVSLAEVVFAEEGSATAALLDRTEFTQPALFALEVALFRLVESWGVRP 673 Query: 185 NVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLL 244 +GHS GEVAAA+V+G ++L DA ++ R + E LL Sbjct: 674 AYVLGHSIGEVAAAHVAGVLSLPDACTLVRARGRLMQQLTATGAMVAVEAAEDEVA-PLL 732 Query: 245 ARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGAD 304 A ++ VN P V +SG+ + V + +TL G + + V + H+ + D Sbjct: 733 AGKEHKVSIAAVNGPASVVVSGDEDVVTAVAETLARQGRKTKRLVVSHAFHSPHMDGMLD 792 Query: 305 KLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQ 364 R P + + GA EL +YW + R VRF + Sbjct: 793 AFREVASRLAYAPPRIPVVSNLTGAVAD---PEELCSPEYWVRHARGAVRFLDGVRTLAD 849 Query: 365 RDVETFVELAEHPTLQLAIHENLAALRDEADDR--PAMVVGTSERTATDLGEFTRNLAQL 422 V T +EL L + L EAD P++ G E A G LA L Sbjct: 850 EGVRTHLELGPDGVLTAMGQDCL----PEADAAFVPSLRPGVQEPHAVLAG-----LAGL 900 Query: 423 AVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 V + W+ + A G+ A P+ P WL Sbjct: 901 YVRGVRVDWDAMFA---GSGARPVA-LPTYAFQHEHYWL 935 >tr|Q0S8W4|Q0S8W4_RHOSR Tax_Id=101510 SubName: Full=Type I polyketide synthase;[Rhodococcus sp.] Length = 3527 Score = 160 bits (405), Expect = 9e-37 Identities = 123/454 (27%), Positives = 183/454 (40%), Gaps = 12/454 (2%) Query: 9 PDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXT 68 PD + +SA T L ++A L D+V HP LTP ++ L Sbjct: 475 PDEVVAWFVSAHTEPALRAQAERLLDYVTEHPGLTPAAVACALLGSRATFDHRAAVIGAR 534 Query: 69 RAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 L++ L A+ ++ R +VF ++ P F Sbjct: 535 PQGLLNGLDALSRGAPSADVVTGVALEAGDRPVFVFPGQGSQWVGMATELLDTSPVFADT 594 Query: 129 VDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAPNVTI 188 V CA A + S + L D++ +VQPALF M LA +WRS G+ P + Sbjct: 595 VRECADALAPYTNFSLLDVLRDRDPAALDRVDVVQPALFAMMVGLAELWRSHGVEPAAVV 654 Query: 189 GHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLARCS 248 GHSQGE+AAAYV+G ++L DA V+ R +T + + + Sbjct: 655 GHSQGEIAAAYVAGALSLSDAALVVAARSRVIGASARRGGGMASVALPADTVREKIQPWA 714 Query: 249 GWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKLRA 308 G +++ +N P ISG + + ++ L G AR I V Y +H + LR Sbjct: 715 GAVEVAAMNGPSATVISGPVDALDALIGQLQGDGVQARRIAVEYASHCA----DVSVLRE 770 Query: 309 AIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRDVE 368 I D L + + I + G + DYW+ NLR VRF++A + Sbjct: 771 PILDVLASITPRRSRIPFYSSVTGGVLDGTALDADYWYRNLRRTVRFEQATRSLAADGYR 830 Query: 369 TFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHDLN 428 FVE HP L + + E L +A VGT R L +FT LA+ V+ L+ Sbjct: 831 LFVESCSHPVLSVPLQETL-----DAAGVAGRAVGTIRRDRAGLRQFTAALAEAQVYGLH 885 Query: 429 YPWECLR-AEPDGAQALPLLDFPNTRMNEIRLWL 461 W+ + A D Q +D P R WL Sbjct: 886 VEWDRVSWARHDDRQ--QWVDLPTYAFQHRRYWL 917 Score = 125 bits (315), Expect = 2e-26 Identities = 109/341 (31%), Positives = 149/341 (43%), Gaps = 17/341 (4%) Query: 592 DTGVTDCWLVTVGGEAATAADGP-----PDPVHAAASAGFRSIGAEHPGVGFRHLDLPAG 646 D V D LV V A DG PD AA S E+P F +DL Sbjct: 2990 DEAVADSPLVIVTRNAMVTDDGQDHDTRPDLAAAAVWGLVGSAQNENPD-RFVLIDLDDE 3048 Query: 647 ATAQDWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEHVLIIGGTGN 706 + A+ V + + EP+LA R+G A R+ VL+ GGTG Sbjct: 3049 SDAET----AVTSALASGEPQLAVRNGTLRAPRLRRMPAVDEPTPFDPGGTVLVTGGTGT 3104 Query: 707 LGLEFCDHFA-HRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR 765 +G H GAR + L SR G A ++RL S A++++ CD+ D +AV+ Sbjct: 3105 VGSLVARHLVTEHGARHVLLTSRRGPDAEGSDRLRSELSGLGAEVSIVACDMSDASAVAA 3164 Query: 766 LAAQHRST-PADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRI 824 L A S P +IHAA + +T + D L KV + +D Sbjct: 3165 LLAGVPSEHPLTAVIHAAGVIDDGTLASLTPERLDAVLRPKVDAAWNLHLLTANSDVRAF 3224 Query: 825 VLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQW----TVHFDLDAS 880 V+ SS +G GQ YAAAN LDA+AH A GL +S+ WG W + +L A Sbjct: 3225 VMFSSLAGILGAPGQANYAAANMFLDALAHHRHALGLPGLSIAWGMWATPSAMTDNLGAI 3284 Query: 881 SMAQLAAIGVIPMPPAEAIALGMQRLGRNA-IVAAFDFDRA 920 +A+ G+IPMP A+ +AL L A VAA FD + Sbjct: 3285 DLARARLSGMIPMPAADGLALLDSALAAGAPTVAAARFDHS 3325 Score = 122 bits (305), Expect = 3e-25 Identities = 121/362 (33%), Positives = 154/362 (42%), Gaps = 48/362 (13%) Query: 564 PETPKLDGRAAAAEVGGFFSNRAWWPGVDTGVTDCWLVTVGGEAATAADGPPDPVHAAAS 623 P+TP AA A + S W D LVT A D P D V AA S Sbjct: 1263 PDTPARAHAAAEATLRAVQS----WLREDRLAETRLLVTTRLAVAVRDDDPVDDVSAAPS 1318 Query: 624 AGFRSIGA---EHPG-VGFRHLDLPAGATAQDWAHPIVAALHTANEPELAYRDGAFYAKR 679 G IGA EHP + LD+ AG + ++A NEP+LA RDG A Sbjct: 1319 WGL--IGAVQNEHPDRITLVDLDVHAGDPS------LIAMALACNEPQLAIRDGVLLAPM 1370 Query: 680 IXXXXXXXXXXXXXCPEH----------VLIIGGTGNLGLEFCDHF-AHRGARRITLVSR 728 + PE VLI GGTG +G H A G RR+ L Sbjct: 1371 LAAVTPAAS-----APEPGPALFGPDGTVLITGGTGTIGRLIARHLVARHGVRRLVL--- 1422 Query: 729 SGESAAVAERLAQLRSATA---AQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIHAAVAY 785 +G A AE A+LR+ A A+++ CDV D AAV+ L A +IHAA Sbjct: 1423 TGRHALDAESAAELRAEFAESEAEVSAVACDVADRAAVAALLAGIPDLSG--VIHAAGVL 1480 Query: 786 ASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQVMYAAA 845 + +T D L KV G + + D VL SSA +GG GQ YAAA Sbjct: 1481 EDATAATLTEDQLHAVLRPKVDGAWHLHELTRDRDVSAFVLFSSAAGVLGGAGQANYAAA 1540 Query: 846 NRMLDAMAHRLRAEGLDCVSVQWGQW------TVHFDLDASSMAQLAAIGVIPMPPAEAI 899 N LDA+A RA GL S+ WG W T H L+A+ + +L G+ + P + Sbjct: 1541 NVFLDALAQHRRARGLPATSMAWGLWDRPSGMTSH--LNAADLDRLQRSGIDTISPESGL 1598 Query: 900 AL 901 AL Sbjct: 1599 AL 1600 Score = 95.9 bits (237), Expect = 3e-17 Identities = 92/379 (24%), Positives = 149/379 (39%), Gaps = 21/379 (5%) Query: 4 AAYRLPDGTIPVL--LSADTPELLDSEATALRDHVAAHPDLTPGP--ISAMLFXXXXXXX 59 AA + T P++ +S T + L ++AT L + + P P ++ L Sbjct: 2192 AAPEVSPSTSPLVWVISGKTGDALRAQATRLAEFLDTDESELPDPADLAYSLATTRSGFT 2251 Query: 60 XXXXXXXXTRAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFY 119 T A+L D L ++ ++ A R + ++F Y Sbjct: 2252 HRAAVIGGTFADLRDGLARIVTGRPGGNVVTGTSA--RGKTAFMFTGQGAQRIGMGRGLY 2309 Query: 120 ESVPAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGI-----VQPALFTQMAALA 174 E+ P F +D A + R + D++ D G A + QPALF AL Sbjct: 2310 EAYPVFARALDEVCSALDEHVETPVRQVIWDES--DGGGATLDSTEYTQPALFAVEVALY 2367 Query: 175 AMWRSFGIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXX 234 + R +GI P+ IGHS GE+ AA+V+G +L DA ++G R Sbjct: 2368 RLLRDWGITPDYLIGHSIGEITAAHVAGVFSLPDAAALVGDRGRLMQSTKPGLMIAV--- 2424 Query: 235 XDRETCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPA 294 R ED+L R G L+ VN V ++G V + L+ G +RV Sbjct: 2425 --RAREEDILPRIDGRVDLAAVNGAESVVLAGSERDVHAVASELSAAGLKTTSLRVERAF 2482 Query: 295 HTSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVR 354 H++L+ D+ A + P + + G A +L +YW ++R+ VR Sbjct: 2483 HSTLMDPILDQFAAVVARLTAQPPKIPVVSNVTGRVATA---DDLMSPEYWTRHIRHAVR 2539 Query: 355 FDKAIAAAVQRDVETFVEL 373 F + A + V VE+ Sbjct: 2540 FHDGVCALDELGVTRLVEV 2558 >tr|B4ER95|B4ER95_STRON Tax_Id=67339 (norA')SubName: Full=Protein modular polyketide synthase NorA';[Streptoverticillium orinoci] Length = 3625 Score = 160 bits (405), Expect = 9e-37 Identities = 128/458 (27%), Positives = 192/458 (41%), Gaps = 24/458 (5%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRA 70 G +P++LSA L ++A LR+ + A P L ++ L RA Sbjct: 2247 GPLPLVLSARGEPALRAQAAGLRERLTADPGLQLADVAGSLLTTRAALEHRAVVLGDGRA 2306 Query: 71 ELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVD 130 EL+ L A+ E PA++R A + + +VF +ES P FR + Sbjct: 2307 ELLAGLAALAHGRETPAVVRGTACAPGKTV-FVFPGQGAQWPGMAAELWESSPVFRKRLG 2365 Query: 131 RCAQA------FEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIAP 184 CA+A F+A +D D +VQPAL+ M ALA +WRS+G+ P Sbjct: 2366 ECAEALAPWVDFDAVEVVRGTATGIDPERVD-----VVQPALWAVMVALAGLWRSYGVEP 2420 Query: 185 NVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLL 244 +GHSQGE+AAA V+G +TL D RV+ +R E + + Sbjct: 2421 AAVVGHSQGEIAAACVAGGLTLADGARVVALRSRALTALAGRGGMLSLALTPAEAGKLVA 2480 Query: 245 ARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGAD 304 R L+ VN P V +SG+ + ++ ++ G +AR I V Y +H+ + + Sbjct: 2481 GRGDDRLSLAAVNGPESVVVSGDTDALEEVLAHCERTGVWARRIPVDYASHSPQVAE--- 2537 Query: 305 KLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQ 364 +RA IQ L + G + GDYW+ NLR VRF+ A+ Sbjct: 2538 -VRAHIQRDLAELRPRTGQVAFFSTVTGRFEDTAGLDGDYWYRNLREPVRFEPAVRELAG 2596 Query: 365 RDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAV 424 FVE + HP L A+ E LA P +VVG+ R F ++A+ Sbjct: 2597 LGFGAFVETSPHPVLTTAVGEALAG----RPGPPPVVVGSLRRGQGGPLRFLASVAEAHT 2652 Query: 425 HDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLP 462 + W L A + ++D P R WLP Sbjct: 2653 RGIAVDWSTLWA----GRTPRVVDLPTYPFQRRRFWLP 2686 Score = 158 bits (399), Expect = 4e-36 Identities = 119/426 (27%), Positives = 176/426 (41%), Gaps = 13/426 (3%) Query: 9 PDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXT 68 P +P +LSA TP L ++A LRDH+A P P I+ L Sbjct: 472 PLSPVPWVLSAQTPRALRAQAARLRDHLADAPVPHPADIAYSLAVTRDALRHRAVVVGRD 531 Query: 69 RAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 EL+ + A+ D P L+ + + R + VF + FR Sbjct: 532 PGELLRGVSALADGEPAPGLVEGEAREVGRTV-LVFPGQGSQWAGMAQPLWRHSTVFRER 590 Query: 129 VDRCAQAFEAQSCGSPRNYLLDKNFQDD--GSAGIVQPALFTQMAALAAMWRSFGIAPNV 186 ++ CA+A S R ++D +D +VQP L+ M +LA +WRS G+ P Sbjct: 591 MEACAEALAPHVDWSLRE-MVDAPAEDARWDRVDVVQPVLWAVMVSLAGLWRSHGVEPAA 649 Query: 187 TIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDLLAR 246 +GHSQGE+AAA V+G ++LED RV+ +R ED LAR Sbjct: 650 VVGHSQGEIAAACVAGALSLEDGARVVALRSRLVAERLAGKGGMVSVAAPVAEAEDRLAR 709 Query: 247 CSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGADKL 306 G L+ VN P V +SG+ ++ ++ G AR + V Y +H+ + ++L Sbjct: 710 RPGRLALAAVNGPSSVVVSGDPAALEELLADCARDGIRARRVAVDYASHSPQVAALREEL 769 Query: 307 RAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQRD 366 AA+ +I G P+ E G++W+ NLR VR + Sbjct: 770 LAALAPIRPRAG----EIPLYSTVTGGPLAGERLTGEHWYRNLRQTVRLAGTVRTLAAAG 825 Query: 367 VETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAVHD 426 FVE + HP L + E L L D A+VVGT R F +L +L Sbjct: 826 HSVFVECSPHPVLTPGLTETLTGL-----DEDALVVGTLRRDDGGPERFLCSLGELFAGG 880 Query: 427 LNYPWE 432 WE Sbjct: 881 RAPDWE 886 Score = 118 bits (295), Expect = 5e-24 Identities = 107/313 (34%), Positives = 141/313 (45%), Gaps = 16/313 (5%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAA 659 +VT G A+ D PPDP AA RS +EHPG F DL D A + AA Sbjct: 3086 IVTRGAVTASDDDPPPDPAAAAVWGLVRSAQSEHPG-RFLLADLDRHP---DSAPALTAA 3141 Query: 660 LHTA---NEPELAYRDGAFYAKRIXXXXXXXXXXXXXCPEH-VLIIGGTGNLGLEFCDHF 715 L TA +EP+LA R G RI P+ VLI G +G LG H Sbjct: 3142 LATALALDEPQLALRAGRVLLPRIQRAPAAQEGTPPWDPQGTVLITGASGTLGRAVARHL 3201 Query: 716 AH-RGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR-LAAQHRST 773 G RR+ LV R G + A RL + A + CD D A++ LA+ + Sbjct: 3202 VTTHGVRRLLLVGRHGGAGEEAARLTTELAGHQATVDWAACDAADREAIAAVLASIPAAH 3261 Query: 774 PADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGC-RIVLCSSARA 832 P +IHAA ++ D A++ + LDA RT +V+ SSA A Sbjct: 3262 PLTAVIHAAGVLDDGVLPALSPQRID-AVFRPKADAARHLDALTRTASPPALVVFSSAAA 3320 Query: 833 TIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDA----SSMAQLAAI 888 T+G GQ YAAAN LDA+ R G S+ WG W+ ++ A + A+LA Sbjct: 3321 TLGSAGQANYAAANAFLDALILARRRAGFPGQSLAWGLWSETSEMTAALGQAGRARLARS 3380 Query: 889 GVIPMPPAEAIAL 901 G+ MP EA+AL Sbjct: 3381 GLQGMPTEEALAL 3393 Score = 102 bits (253), Expect = 4e-19 Identities = 131/454 (28%), Positives = 173/454 (38%), Gaps = 42/454 (9%) Query: 573 AAAAEVGGFFSNRAWWPGVDTGVTDCWLVTVGGEAATAADGPPDPVHAAASAGFRSIGAE 632 AAA EV G A + G + L+T G AAT + DP AAA RS +E Sbjct: 1325 AAAREVTGRALALAQRWLAEDGPSRLVLLTRGAVAATGTE-TADPALAAAWGLLRSAQSE 1383 Query: 633 HPGVGFRHLDLPAGATAQDWAHPIVAALHTANEPELAYRDGAFYAKRIXXXXXXXXXXXX 692 HP L L A + AA+ + +EP+LA R G A R+ Sbjct: 1384 HPD----RLVLVDWDGQPSSAAALPAAV-SGDEPQLALRGGRILAPRLRRLPVTRPAPQA 1438 Query: 693 XCPEH-VLIIGGTGNLGLEFCDHFAH-RGARRITLVSRSGESAAVAERLAQLRSATAAQI 750 E VL+ G G LG H G RR+ LVSR G A A L A + Sbjct: 1439 FDAEGTVLVTGAAGVLGRVITRHLVRTHGVRRLLLVSRRGPEAPGAAELTAELGELGASV 1498 Query: 751 AVTRCDVGDPAAVS----RLAAQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKV 806 T CDV D AA++ R+ A+H P ++HA S + D + K+ Sbjct: 1499 RWTACDVADRAALADVLARIPARH---PLRAVVHAGGLLDDGVVSALAPDRLETVFRPKI 1555 Query: 807 VGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSV 866 + + + +D VL SSA T G GQ YAAAN LDA A R++GL +S+ Sbjct: 1556 DAVVNLHEL--TSDLTAFVLFSSAAGTFGTAGQGGYAAANAFLDAFAGLRRSQGLPALSL 1613 Query: 867 QWGQWTVHFDLDA----SSMAQLAAIGVIPMPPAEAIALGMQRLGRN---AIVAAFDFDR 919 WG W L A + ++ GV + AE AL L + D Sbjct: 1614 AWGLWAETSALTARMSDTDRDRMHRSGVTGLSGAEGTALFDAALAAGPPMVLPTRLDLAA 1673 Query: 920 ARPVLETFGYGPLVSELLSPVSETAAPA--------------EPADLPGRLSNXXXXXXX 965 R G L+ L+ P + A A P D G + Sbjct: 1674 VRARAAAEGVPALLRALVKPPARRAGTATESGSALARELAALAPQDRAGAVLETVRAQAA 1733 Query: 966 XXXXXXXDTSV-PMVA---LGLDSLQALELRRRV 995 V P A LG DSL +ELR R+ Sbjct: 1734 AVLGHTGTAEVEPQRAFKELGFDSLTGVELRNRL 1767 >tr|Q0RMN9|Q0RMN9_FRAAA Tax_Id=326424 SubName: Full=Putative type I polyketide synthase; EC=2.3.1.-;[Frankia alni] Length = 1911 Score = 160 bits (404), Expect = 1e-36 Identities = 129/458 (28%), Positives = 183/458 (39%), Gaps = 29/458 (6%) Query: 13 IPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRAEL 72 +P +LSA + + + ++A LRD VAA L+ + L R EL Sbjct: 508 VPWVLSARSEQAMRAQARRLRDSVAAGTQLSVAAVGYSLATTRARFDHRQVVIGANREEL 567 Query: 73 IDALQAMIDRYEHPALIRTDPAAI-RRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVDR 131 + L A+ + A A R +VF Y S P F ++ Sbjct: 568 LAGLTALAEHGPDGATAAASAVASPTARTVFVFPGQGSQWLGMGAELYASSPVFAEQIRA 627 Query: 132 CAQAFEA--------QSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGIA 183 CAQA CG P+ LD+ +VQP LF M +L +WRS G+ Sbjct: 628 CAQALGPWVDWSLIDTVCGGPQAADLDR-------VDVVQPTLFAVMVSLDRVWRSLGVE 680 Query: 184 PNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDL 243 P+ IGHSQGE+AAA+ +G ++L DA R++ +R ++ L Sbjct: 681 PDAVIGHSQGEIAAAHAAGALSLADATRIVALRSRMLAKVAGAGGMAGILLPEQRV-RKL 739 Query: 244 LARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGA 303 L R + VN P +SGE V+ +V G AR I P H+ L+ A Sbjct: 740 LDRWDDRIVIGAVNGPNSTTVSGEAGAVRELVALCEAQGVRARWIPASVPGHSPLVDQFA 799 Query: 304 DKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAV 363 D+LRA + P T + G P + DYWF NLR VRF +A + Sbjct: 800 DQLRAELAGITPLP----TSVTFHSTVTGGPHDTRELDADYWFRNLREPVRFQSTMARLL 855 Query: 364 QRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLA 423 + +E++ HP L L I E L D + +VVGT R L R+ A+ Sbjct: 856 DGERSAVLEISPHPLLALNIQEIL----DTSPATAGLVVGTLRRGEGGLARLYRSAAEAF 911 Query: 424 VHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWL 461 + WE A DG +D P R WL Sbjct: 912 AAGVPVAWEAAFAGWDGG----WVDLPTYAFQRRRYWL 945 Score = 112 bits (281), Expect = 2e-22 Identities = 127/428 (29%), Positives = 161/428 (37%), Gaps = 51/428 (11%) Query: 616 DPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAALHTANEPELAYRDGAF 675 DP A RS E+PG R + + WA + A EP+L R GA Sbjct: 1378 DPAATAVWGLVRSAQTENPG---RFALVDTDDSPASWA--CLPAAAATGEPQLRIRAGAL 1432 Query: 676 YAKRIXXXXXXXXXXXXX-------------CPEHVLIIGGTGNLGLEFCDHFAHR-GAR 721 R+ VLI GGT LG H R G R Sbjct: 1433 SRPRLAQVHRGTQPGGSRDGSGEQAVDGPDLTSGTVLITGGTSGLGALLARHLVRRHGVR 1492 Query: 722 RITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRL-AAQHRSTPADLIIH 780 R+ L SR G+ A A L A + + CDV AV+ L AA +P ++H Sbjct: 1493 RLVLTSRRGQRAPGASALRDELVGAGAHVEIVACDVTSRQAVAELIAAAPPESPWTAVVH 1552 Query: 781 AAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQV 840 A + +T D L KV G + +A D VL SS +G GQ Sbjct: 1553 CAGVLGDGVVAALTGQQVDAVLAPKVHGAWHLHEATRHLDLSAFVLFSSIAGVLGTAGQA 1612 Query: 841 MYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT----VHFDLDASSMAQLAAIGVIPMPPA 896 YAAAN LD +A RAEGL S+ WG W + +LD + +LA GV+PM Sbjct: 1613 NYAAANAFLDGLAQARRAEGLAASSLCWGFWAQRSEMSAELDEVDVERLARQGVLPMASH 1672 Query: 897 EAIAL--GMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELL-SP----VSETAAPAE- 948 E +AL L +V A T G PL+ +LL SP + T P E Sbjct: 1673 EGLALFDAALALDEPVLVPARLHLSPSDAARTGGGPPLLRDLLGSPGAGAGTGTGGPGER 1732 Query: 949 -PAD--LPGRLSNXXXXXXXXXXXXXXDTSVPMV----------------ALGLDSLQAL 989 PAD L RL +V LG+DSL AL Sbjct: 1733 GPADAGLAQRLGALPMADAEAPLRDAVREQTALVLGHADAGRIGPTMAFKELGIDSLTAL 1792 Query: 990 ELRRRVKA 997 ELR R+ A Sbjct: 1793 ELRNRLMA 1800 >tr|B3TMP1|B3TMP1_9ACTO Tax_Id=46161 SubName: Full=Polyketide synthase;[Actinomadura kijaniata] Length = 3921 Score = 159 bits (402), Expect = 2e-36 Identities = 131/459 (28%), Positives = 200/459 (43%), Gaps = 32/459 (6%) Query: 11 GTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFXXXXXXXXXXXXXXXTRA 70 G P L+SA T L +A L D AAHPD+ P I+ L TR Sbjct: 491 GPPPWLVSARTEPALRGQARRLLDFAAAHPDVEPADIAHALVHERDHHEHRAAVVADTRE 550 Query: 71 ELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAEVD 130 +L+ L+A+ + ++R ++ R +VF E+ FR + Sbjct: 551 DLLAGLRALAEGEAAANVVRGRGSSARTV--FVFPGQGSQWERMAVDLLETSAVFRDHLH 608 Query: 131 RCAQAFEAQSC--------GSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSFGI 182 CA A + G+P LD+ +VQPALF M +LA +W++ GI Sbjct: 609 ACADALAPHTGWSLVDVLRGAPDAPSLDR-------VDVVQPALFAMMVSLARVWQAAGI 661 Query: 183 APNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCED 242 P+ +GHSQGE+AAA+V+G +TL+DA R++ +R E E Sbjct: 662 RPDAVVGHSQGEIAAAHVAGALTLDDAARIVALRSRALLDLAGSGGMASVPLPPAEV-EA 720 Query: 243 LLARCSGW-AQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHD 301 LL R ++ VNSP ++G ++ +VD+ G AR+I V Y +HT + Sbjct: 721 LLDRPDRRNLGVAAVNSPGSTVVAGAAGELRELVDSCQADGVPARLIPVDYASHTPHVEP 780 Query: 302 GADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAA 361 D++ + + P+ D+ PI + GDYW+ NLR+ VRF++ A Sbjct: 781 VRDRIARDLAGIVPRPA----DVPFYSTVTAGPIDTGGLDGDYWYTNLRHRVRFEETTRA 836 Query: 362 AVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQ 421 + F+E++ HP L + I E + E D A+ VGT R D LA+ Sbjct: 837 LLADGHTLFIEVSPHPVLTVPIQETV-----EDDGGAAVAVGTLRRDRGDRTRLLTALAE 891 Query: 422 LAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLW 460 V+ + W R PD +A+P +D P R W Sbjct: 892 AHVNGASPDWS--RTVPD-REAVP-VDLPTYAFAGERYW 926 Score = 128 bits (321), Expect = 5e-27 Identities = 110/390 (28%), Positives = 151/390 (38%), Gaps = 18/390 (4%) Query: 69 RAELIDALQAMIDRYEHPALIRTDPAAIRRRIGYVFXXXXXXXXXXXXLFYESVPAFRAE 128 RAEL L A+ HPA++R A R VF E P F Sbjct: 2620 RAELRAGLAAVAAGEPHPAVVRGAAPAGPVRTVLVFPGQGSQWEGMALDLLERSPVFAEH 2679 Query: 129 VDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAG-----IVQPALFTQMAALAAMWRSFGIA 183 + C A + S LLD G+ G +VQPALF M +LA +W++ G+ Sbjct: 2680 LRACTDALAPHTGWS----LLDVLRGAPGAPGLDRVDVVQPALFAVMTSLAELWKAAGVV 2735 Query: 184 PNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRXXXXXXXXXXXXXXXXXXXDRETCEDL 243 P+ GHSQGE+AAAYV+G ++L DA V+ +R L Sbjct: 2736 PDAVAGHSQGEIAAAYVAGALSLPDAALVVALRSRILTRLAGTGTMASVPLPADAVAGRL 2795 Query: 244 LARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIHDGA 303 A L+ +N P ++G + V+ V G AR+I V Y +HT I Sbjct: 2796 AAGADADVHLAAINGPDSSVVAGGADAVRAFVARCEADGVRARLIAVDYASHTPHIETLR 2855 Query: 304 DKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIAAAV 363 D+L A+ V G + +EL G YW+ NLR+ V+F A + Sbjct: 2856 DELARALAPVRPRAGTVPFYSAVTGGIVDG---AELDAG-YWYRNLRHTVQFGITTEALL 2911 Query: 364 QRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLA 423 FVE A HP L + + + L E A +GT R D A+ Sbjct: 2912 DAGHRLFVEAAPHPVLTVGVRQTL-----ERAGAGAAAIGTLRRDEGDARALLTAFAEAH 2966 Query: 424 VHDLNYPWECLRAEPDGAQALPLLDFPNTR 453 VH W + G LP F R Sbjct: 2967 VHGAPLDWTRVLTPGTGKVDLPTYAFQRDR 2996 Score = 104 bits (260), Expect = 6e-20 Identities = 99/312 (31%), Positives = 130/312 (41%), Gaps = 18/312 (5%) Query: 600 LVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAA 659 LV+ G + D AA RS +E+P F+ +D+ AG T +AA Sbjct: 3399 LVSRGAVPGGGREDVTDLAAAAVWGLVRSAQSENP-FRFQLVDVDAGTTED-----ALAA 3452 Query: 660 LHTANEPELAYRDGAFYAKRIXXXXXXXXXXXXX---CPEHVLIIGGTGNLGLEFCDHF- 715 EP+ A R G R+ VL+ GGTG LG H Sbjct: 3453 ALALGEPQAAIRGGKVRLPRLARRPAGDPGQGPEVFRADGTVLVTGGTGTLGGLVARHLV 3512 Query: 716 -AHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSR-LAAQHRST 773 AH G R + LVSR+G +A A LA + A + VT CD D A++ LAA Sbjct: 3513 TAH-GVRHLVLVSRAGLAADGAPDLAAELAGLGATVTVTACDTADRDALAGVLAAIPGEH 3571 Query: 774 PADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARAT 833 P ++HAA ++T D D L K + D VL SSA T Sbjct: 3572 PLTGVVHAAGTLDDATVPNLTPDRLDTVLRPKADAAWNLHVLTAGLDLAAFVLFSSAAGT 3631 Query: 834 IGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQ-----LAAI 888 +G GQ YAAAN LDA+A RA GL VS+ WG W L Q A Sbjct: 3632 LGAPGQANYAAANAFLDALAAHRRALGLPAVSMAWGPWEPASALTRGLAEQDQARVTARR 3691 Query: 889 GVIPMPPAEAIA 900 G++P+ +A+A Sbjct: 3692 GLVPLSTGDALA 3703 Score = 90.1 bits (222), Expect = 1e-15 Identities = 93/332 (28%), Positives = 124/332 (37%), Gaps = 37/332 (11%) Query: 698 VLIIGGTGNLGLEFCDHFA-HRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCD 756 VL+ GGTG LG H G + L SRSG AA A L + A + V CD Sbjct: 1742 VLVTGGTGTLGAAVARHLVVEHGVGHLLLASRSGPDAAGAAELRAELAGLGATVTVRACD 1801 Query: 757 VGDPAAVSRLA-AQHRSTPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDA 815 D + RL A P ++H+A + + D L K+ + + Sbjct: 1802 TSDRDDLRRLLDAIPPEHPLTAVVHSAGVTDDAAVGVLEAEQLDPVLRPKIDAAWHLHEL 1861 Query: 816 FPRTDGCRIVLCSSARATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWT--- 872 D VL SS T+G GQ YAA N LDA+A RA GL VS+ WG W Sbjct: 1862 TQDHDLSAFVLFSSLAGTLGNPGQANYAAGNTFLDALAAHRRARGLPAVSLAWGLWRRAS 1921 Query: 873 -VHFDLDASSMAQLAAIGVIPMPPAEAIAL---GMQRLGRNAIVAAFDFDRARPVLE--- 925 + +L +A + + AEA+AL G+ + + A D R E Sbjct: 1922 GITAELFEEKRHAVAHDVLTTLSDAEALALFDIGLDDGRPDLVPAGLDLAAIRAAAEERP 1981 Query: 926 -------------------TFGYGPLVSELLSPVSETAAPAEPAD-LPGRLSNXXXXXXX 965 T G G L EL + AE D L + Sbjct: 1982 APAVLRGFLRAPRRRAGGRTGGQGALQRELAG-----RSEAERFDFLLDLVRGDIGVVLG 2036 Query: 966 XXXXXXXDTSVPMVALGLDSLQALELRRRVKA 997 D P+ +G DSL A+ELR R+ A Sbjct: 2037 HPAPETIDPRRPLQEIGFDSLTAVELRNRLNA 2068 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.320 0.135 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 6,817,853,917 Number of extensions: 263290676 Number of successful extensions: 680953 Number of sequences better than 10.0: 6810 Number of HSP's gapped: 673793 Number of HSP's successfully gapped: 10654 Length of query: 1024 Length of database: 3,846,993,858 Length adjustment: 148 Effective length of query: 876 Effective length of database: 2,178,263,814 Effective search space: 1908159101064 Effective search space used: 1908159101064 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 86 (37.7 bits)