BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MMAR_3838
         (491 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,275,203 sequences; 3,846,993,858 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|B2HNJ6|COBQ_MYCMM Tax_Id=216594 (cobQ)RecName: Full=Cobyric a...   953   0.0  
sp|A0PU57|COBQ_MYCUA Tax_Id=362242 (cobQ)RecName: Full=Cobyric a...   937   0.0  
sp|P0A532|COBQ_MYCTU Tax_Id=1773 (cobQ)RecName: Full=Cobyric aci...   822   0.0  
sp|A5TYY1|COBQ_MYCTA Tax_Id=419947 (cobQ)RecName: Full=Cobyric a...   822   0.0  
sp|C1AJT1|COBQ_MYCBT Tax_Id=561275 (cobQ)RecName: Full=Cobyric a...   822   0.0  
sp|A1KF76|COBQ_MYCBP Tax_Id=410289 (cobQ)RecName: Full=Cobyric a...   822   0.0  
sp|P0A533|COBQ_MYCBO Tax_Id=1765 (cobQ)RecName: Full=Cobyric aci...   822   0.0  
tr|C6DRR2|C6DRR2_MYCTK Tax_Id=478434 SubName: Full=Cobyric acid ...   822   0.0  
tr|A5WIW2|A5WIW2_MYCTF Tax_Id=336982 SubName: Full=Cobyric acid ...   822   0.0  
tr|A2VNH0|A2VNH0_MYCTU Tax_Id=348776 SubName: Full=Cobyric acid ...   822   0.0  
sp|A4T0R6|COBQ_MYCGI Tax_Id=350054 (cobQ)RecName: Full=Cobyric a...   768   0.0  
sp|A1T225|COBQ_MYCVP Tax_Id=350058 (cobQ)RecName: Full=Cobyric a...   746   0.0  
tr|C1YJM9|C1YJM9_NOCDA Tax_Id=446468 SubName: Full=Adenosylcobyr...   696   0.0  
tr|A1SJM8|A1SJM8_NOCSJ Tax_Id=196162 SubName: Full=Adenosylcobyr...   668   0.0  
tr|A1SKP7|A1SKP7_NOCSJ Tax_Id=196162 SubName: Full=Adenosylcobyr...   652   0.0  
tr|C7MTR3|C7MTR3_SACVD Tax_Id=471857 SubName: Full=Adenosylcobyr...   645   0.0  
tr|C1WP45|C1WP45_9ACTO Tax_Id=479435 SubName: Full=Adenosylcobyr...   561   e-158
tr|Q47T70|Q47T70_THEFY Tax_Id=269800 SubName: Full=Adenosylcobyr...   534   e-150
tr|C4RPI9|C4RPI9_9ACTO Tax_Id=219305 SubName: Full=Cobyric acid ...   517   e-144
tr|A4XAN6|A4XAN6_SALTO Tax_Id=369723 SubName: Full=Adenosylcobyr...   513   e-143
tr|A8M1Q8|A8M1Q8_SALAI Tax_Id=391037 SubName: Full=Cobyric acid ...   510   e-142
tr|C8XIY4|C8XIY4_NAKMY Tax_Id=479431 SubName: Full=Cobyric acid ...   504   e-140
tr|C0UBE6|C0UBE6_9ACTO Tax_Id=526225 SubName: Full=Adenosylcobyr...   498   e-139
tr|D1A9H5|D1A9H5_THECU Tax_Id=471852 SubName: Full=Cobyric acid ...   493   e-137
tr|C7QGK0|C7QGK0_CATAD Tax_Id=479433 SubName: Full=Cobyric acid ...   493   e-137
tr|C4DVK9|C4DVK9_9ACTO Tax_Id=446470 SubName: Full=Adenosylcobyr...   487   e-135
tr|C4E3Z2|C4E3Z2_STRRS Tax_Id=479432 SubName: Full=Adenosylcobyr...   486   e-135
sp|Q829J5|COBQ_STRAW Tax_Id=33903 (cobQ)RecName: Full=Cobyric ac...   483   e-134
tr|C9NHQ4|C9NHQ4_9ACTO Tax_Id=591167 SubName: Full=Cobyric acid ...   479   e-133
tr|A8LG25|A8LG25_FRASN Tax_Id=298653 SubName: Full=Cobyric acid ...   476   e-132
sp|Q2J9S7|COBQ_FRASC Tax_Id=106370 (cobQ)RecName: Full=Cobyric a...   474   e-131
tr|C2ANV9|C2ANV9_TSUPA Tax_Id=521096 SubName: Full=Adenosylcobyr...   473   e-131
tr|Q0RLS3|Q0RLS3_FRAAA Tax_Id=326424 (bioD)SubName: Full=Dethiob...   472   e-131
tr|C9YZR0|C9YZR0_STRSW Tax_Id=680198 (cobQ)SubName: Full=Cobyric...   470   e-130
tr|B1W1S6|B1W1S6_STRGG Tax_Id=455632 SubName: Full=Putative coby...   469   e-130
sp|A4FM88|COBQ_SACEN Tax_Id=405948 (cobQ)RecName: Full=Cobyric a...   468   e-130
tr|C6WER7|C6WER7_ACTMD Tax_Id=446462 SubName: Full=Cobyric acid ...   468   e-130
sp|Q6AAP6|COBQ_PROAC Tax_Id=1747 (cobQ)RecName: Full=Cobyric aci...   467   e-129
sp|Q9RJ20|COBQ_STRCO Tax_Id=1902 (cobQ)RecName: Full=Cobyric aci...   466   e-129
sp|Q5YSA4|COBQ_NOCFA Tax_Id=37329 (cobQ)RecName: Full=Cobyric ac...   461   e-127
sp|C1B2W9|COBQ_RHOOB Tax_Id=632772 (cobQ)RecName: Full=Cobyric a...   458   e-127
sp|Q0S258|COBQ_RHOSR Tax_Id=101510 (cobQ)RecName: Full=Cobyric a...   456   e-126
sp|Q1BAC5|COBQ_MYCSS Tax_Id=164756 (cobQ)RecName: Full=Cobyric a...   455   e-126
sp|A1UEN7|COBQ_MYCSK Tax_Id=189918 (cobQ)RecName: Full=Cobyric a...   455   e-126
sp|A3PY44|COBQ_MYCSJ Tax_Id=164757 (cobQ)RecName: Full=Cobyric a...   455   e-126
tr|C0ZY63|C0ZY63_RHOE4 Tax_Id=234621 (cobQ)SubName: Full=Cobyric...   452   e-125
tr|C3JM17|C3JM17_RHOER Tax_Id=596309 (cobQ)SubName: Full=Cobyric...   449   e-124
tr|Q1AYC4|Q1AYC4_RUBXD Tax_Id=266117 SubName: Full=Adenosylcobyr...   444   e-123
sp|A0QVI7|COBQ_MYCS2 Tax_Id=246196 (cobQ)RecName: Full=Cobyric a...   440   e-121
sp|Q73VS8|COBQ_MYCPA Tax_Id=1770 (cobQ)RecName: Full=Cobyric aci...   438   e-121

>sp|B2HNJ6|COBQ_MYCMM Tax_Id=216594 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium marinum]
          Length = 491

 Score =  953 bits (2463), Expect = 0.0
 Identities = 479/479 (100%), Positives = 479/479 (100%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR
Sbjct: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR
Sbjct: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG
Sbjct: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA
Sbjct: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG
Sbjct: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGL 360
           TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGL
Sbjct: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGL 360

Query: 361 GLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMW 420
           GLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMW
Sbjct: 361 GLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMW 420

Query: 421 HGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARHGC 479
           HGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARHGC
Sbjct: 421 HGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARHGC 479


>sp|A0PU57|COBQ_MYCUA Tax_Id=362242 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium ulcerans]
          Length = 491

 Score =  937 bits (2423), Expect = 0.0
 Identities = 473/479 (98%), Positives = 474/479 (98%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR
Sbjct: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLA+TAHR
Sbjct: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLADTAHR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HAELPTIVVGDIDRGGVFAAFFG
Sbjct: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAELPTIVVGDIDRGGVFAAFFG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           TIALLS EDQALVAGFVVNKFRGDLDLLAPGLRDLE VTGRQVFGTLPWHADLWLDSEDA
Sbjct: 181 TIALLSVEDQALVAGFVVNKFRGDLDLLAPGLRDLERVTGRQVFGTLPWHADLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDLTGRRAAS GAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG
Sbjct: 241 LDLTGRRAASAGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGL 360
           TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGL
Sbjct: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGL 360

Query: 361 GLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMW 420
           GLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMW
Sbjct: 361 GLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMW 420

Query: 421 HGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARHGC 479
           HGSLEGDALREAFLRETLGLT SGTSFSAARERRLDLLGDLVERHLDVDALLALARHGC
Sbjct: 421 HGSLEGDALREAFLRETLGLTESGTSFSAARERRLDLLGDLVERHLDVDALLALARHGC 479


>sp|P0A532|COBQ_MYCTU Tax_Id=1773 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium tuberculosis]
          Length = 494

 Score =  822 bits (2124), Expect = 0.0
 Identities = 417/482 (86%), Positives = 435/482 (90%), Gaps = 3/482 (0%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR
Sbjct: 1   MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA  TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W  GR+ LAE A R
Sbjct: 61  AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFAAF G
Sbjct: 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL+AEDQALVAGFVVNKFRGD DLLAPGLRDLE VTGR+V+GTLPWH DLWLDSEDA
Sbjct: 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDL GRRAA TGA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG
Sbjct: 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357
           TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP   V E 
Sbjct: 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417
           +GLGLLDVET F   KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG
Sbjct: 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420

Query: 418 TMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477
           TMWHGSLEGDALREAFLRETLGL  SG+ F AARERRLDLLGDLVERHLDVDALL LARH
Sbjct: 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480

Query: 478 GC 479
           GC
Sbjct: 481 GC 482


>sp|A5TYY1|COBQ_MYCTA Tax_Id=419947 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium tuberculosis]
          Length = 494

 Score =  822 bits (2124), Expect = 0.0
 Identities = 417/482 (86%), Positives = 435/482 (90%), Gaps = 3/482 (0%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR
Sbjct: 1   MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA  TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W  GR+ LAE A R
Sbjct: 61  AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFAAF G
Sbjct: 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL+AEDQALVAGFVVNKFRGD DLLAPGLRDLE VTGR+V+GTLPWH DLWLDSEDA
Sbjct: 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDL GRRAA TGA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG
Sbjct: 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357
           TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP   V E 
Sbjct: 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417
           +GLGLLDVET F   KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG
Sbjct: 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420

Query: 418 TMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477
           TMWHGSLEGDALREAFLRETLGL  SG+ F AARERRLDLLGDLVERHLDVDALL LARH
Sbjct: 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480

Query: 478 GC 479
           GC
Sbjct: 481 GC 482


>sp|C1AJT1|COBQ_MYCBT Tax_Id=561275 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium bovis]
          Length = 494

 Score =  822 bits (2124), Expect = 0.0
 Identities = 417/482 (86%), Positives = 435/482 (90%), Gaps = 3/482 (0%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR
Sbjct: 1   MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA  TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W  GR+ LAE A R
Sbjct: 61  AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFAAF G
Sbjct: 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL+AEDQALVAGFVVNKFRGD DLLAPGLRDLE VTGR+V+GTLPWH DLWLDSEDA
Sbjct: 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDL GRRAA TGA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG
Sbjct: 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357
           TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP   V E 
Sbjct: 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417
           +GLGLLDVET F   KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG
Sbjct: 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420

Query: 418 TMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477
           TMWHGSLEGDALREAFLRETLGL  SG+ F AARERRLDLLGDLVERHLDVDALL LARH
Sbjct: 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480

Query: 478 GC 479
           GC
Sbjct: 481 GC 482


>sp|A1KF76|COBQ_MYCBP Tax_Id=410289 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium bovis]
          Length = 494

 Score =  822 bits (2124), Expect = 0.0
 Identities = 417/482 (86%), Positives = 435/482 (90%), Gaps = 3/482 (0%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR
Sbjct: 1   MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA  TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W  GR+ LAE A R
Sbjct: 61  AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFAAF G
Sbjct: 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL+AEDQALVAGFVVNKFRGD DLLAPGLRDLE VTGR+V+GTLPWH DLWLDSEDA
Sbjct: 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDL GRRAA TGA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG
Sbjct: 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357
           TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP   V E 
Sbjct: 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417
           +GLGLLDVET F   KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG
Sbjct: 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420

Query: 418 TMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477
           TMWHGSLEGDALREAFLRETLGL  SG+ F AARERRLDLLGDLVERHLDVDALL LARH
Sbjct: 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480

Query: 478 GC 479
           GC
Sbjct: 481 GC 482


>sp|P0A533|COBQ_MYCBO Tax_Id=1765 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium bovis]
          Length = 494

 Score =  822 bits (2124), Expect = 0.0
 Identities = 417/482 (86%), Positives = 435/482 (90%), Gaps = 3/482 (0%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR
Sbjct: 1   MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA  TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W  GR+ LAE A R
Sbjct: 61  AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFAAF G
Sbjct: 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL+AEDQALVAGFVVNKFRGD DLLAPGLRDLE VTGR+V+GTLPWH DLWLDSEDA
Sbjct: 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDL GRRAA TGA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG
Sbjct: 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357
           TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP   V E 
Sbjct: 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417
           +GLGLLDVET F   KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG
Sbjct: 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420

Query: 418 TMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477
           TMWHGSLEGDALREAFLRETLGL  SG+ F AARERRLDLLGDLVERHLDVDALL LARH
Sbjct: 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480

Query: 478 GC 479
           GC
Sbjct: 481 GC 482


>tr|C6DRR2|C6DRR2_MYCTK Tax_Id=478434 SubName: Full=Cobyric acid
           synthase cobQ1;[Mycobacterium tuberculosis]
          Length = 494

 Score =  822 bits (2124), Expect = 0.0
 Identities = 417/482 (86%), Positives = 435/482 (90%), Gaps = 3/482 (0%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR
Sbjct: 1   MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA  TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W  GR+ LAE A R
Sbjct: 61  AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFAAF G
Sbjct: 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL+AEDQALVAGFVVNKFRGD DLLAPGLRDLE VTGR+V+GTLPWH DLWLDSEDA
Sbjct: 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDL GRRAA TGA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG
Sbjct: 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357
           TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP   V E 
Sbjct: 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417
           +GLGLLDVET F   KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG
Sbjct: 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420

Query: 418 TMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477
           TMWHGSLEGDALREAFLRETLGL  SG+ F AARERRLDLLGDLVERHLDVDALL LARH
Sbjct: 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480

Query: 478 GC 479
           GC
Sbjct: 481 GC 482


>tr|A5WIW2|A5WIW2_MYCTF Tax_Id=336982 SubName: Full=Cobyric acid
           synthase cobQ1;[Mycobacterium tuberculosis]
          Length = 494

 Score =  822 bits (2124), Expect = 0.0
 Identities = 417/482 (86%), Positives = 435/482 (90%), Gaps = 3/482 (0%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR
Sbjct: 1   MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA  TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W  GR+ LAE A R
Sbjct: 61  AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFAAF G
Sbjct: 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL+AEDQALVAGFVVNKFRGD DLLAPGLRDLE VTGR+V+GTLPWH DLWLDSEDA
Sbjct: 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDL GRRAA TGA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG
Sbjct: 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357
           TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP   V E 
Sbjct: 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417
           +GLGLLDVET F   KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG
Sbjct: 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420

Query: 418 TMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477
           TMWHGSLEGDALREAFLRETLGL  SG+ F AARERRLDLLGDLVERHLDVDALL LARH
Sbjct: 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480

Query: 478 GC 479
           GC
Sbjct: 481 GC 482


>tr|A2VNH0|A2VNH0_MYCTU Tax_Id=348776 SubName: Full=Cobyric acid
           synthase cobQ1;[Mycobacterium tuberculosis C]
          Length = 494

 Score =  822 bits (2124), Expect = 0.0
 Identities = 417/482 (86%), Positives = 435/482 (90%), Gaps = 3/482 (0%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR
Sbjct: 1   MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA  TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W  GR+ LAE A R
Sbjct: 61  AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFAAF G
Sbjct: 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL+AEDQALVAGFVVNKFRGD DLLAPGLRDLE VTGR+V+GTLPWH DLWLDSEDA
Sbjct: 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDL GRRAA TGA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG
Sbjct: 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357
           TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP   V E 
Sbjct: 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417
           +GLGLLDVET F   KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG
Sbjct: 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420

Query: 418 TMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477
           TMWHGSLEGDALREAFLRETLGL  SG+ F AARERRLDLLGDLVERHLDVDALL LARH
Sbjct: 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480

Query: 478 GC 479
           GC
Sbjct: 481 GC 482


>sp|A4T0R6|COBQ_MYCGI Tax_Id=350054 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium gilvum]
          Length = 491

 Score =  768 bits (1982), Expect = 0.0
 Identities = 379/478 (79%), Positives = 418/478 (87%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGK+ +T GLCRA ARRGV+VAP+KAQNMSNNSMVC    GAG EIGR
Sbjct: 1   MTGLLVAGTTSDAGKTAVTTGLCRALARRGVKVAPYKAQNMSNNSMVCTSVDGAGAEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA ATPE AMNPVLLKPGSD RSHVVLMGR WG+++SS+W EGR+ LA  AH 
Sbjct: 61  AQWVQALAARATPEPAMNPVLLKPGSDRRSHVVLMGRPWGQVSSSDWLEGRRALATAAHE 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFD+LA+RY+VVVAEGAGSP EINLRAGDYVN+GLA HA LPT+VVGDIDRGGVFAAFFG
Sbjct: 121 AFDELASRYEVVVAEGAGSPTEINLRAGDYVNLGLARHAGLPTVVVGDIDRGGVFAAFFG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALLS +DQAL+AGFVVNKFRGD+DLLAPGLRDLE +TGR+V+GTLPWH D+WLDSEDA
Sbjct: 181 TVALLSPQDQALIAGFVVNKFRGDVDLLAPGLRDLERLTGRRVYGTLPWHPDIWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           L+L GRR+A +GA RVAV+RLPRISNFTDVDALGLEPDLDVVFAS P  L DADL+V+PG
Sbjct: 241 LELAGRRSAQSGARRVAVIRLPRISNFTDVDALGLEPDLDVVFASHPGSLADADLVVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGL 360
           TRATIADLAWLR+RGLD AL  HVAAG+P+LGICGGFQMLGRVIRDP GVEGPVA  DGL
Sbjct: 301 TRATIADLAWLRSRGLDSALRRHVAAGRPVLGICGGFQMLGRVIRDPHGVEGPVAGVDGL 360

Query: 361 GLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMW 420
           GLLDVETTFG +KVLRLP G+  G  A+GYEIHHGRIT GD   +FL GAR GQVFGTMW
Sbjct: 361 GLLDVETTFGPDKVLRLPSGRWFGAPATGYEIHHGRITRGDGVDEFLDGARCGQVFGTMW 420

Query: 421 HGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARHG 478
           HG+LEGD LR  FL+E LG+  SG SF AARE RLDLLGDLVERHLDVDALL LA+ G
Sbjct: 421 HGALEGDELRSRFLQEALGVAPSGVSFPAAREARLDLLGDLVERHLDVDALLDLAKTG 478


>sp|A1T225|COBQ_MYCVP Tax_Id=350058 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium vanbaalenii]
          Length = 490

 Score =  746 bits (1927), Expect = 0.0
 Identities = 371/477 (77%), Positives = 408/477 (85%), Gaps = 1/477 (0%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLL+AGTTSDAGK+ +T GLCRA ARRG++VAP+KAQNMSNNSMVC G  G GVEIGR
Sbjct: 1   MTGLLIAGTTSDAGKTAVTTGLCRALARRGLKVAPYKAQNMSNNSMVCAGDDG-GVEIGR 59

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA ATPEAAMNPVLLKPGSD RSHVVLMGR WG ++SS+W EGR+ LA  AH 
Sbjct: 60  AQWVQALAARATPEAAMNPVLLKPGSDRRSHVVLMGRPWGHVSSSDWLEGRRALAAAAHA 119

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           A+DDLA RYDV+VAEGAGSP EINLRAGDYVN+GLA HA LPT+VVGDIDRGGVFAAFFG
Sbjct: 120 AYDDLAGRYDVIVAEGAGSPTEINLRAGDYVNLGLARHAGLPTVVVGDIDRGGVFAAFFG 179

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALLS EDQAL+AGFVVNKFRGD  LLAPGLRDLE +TGR+V+GTLPWH DLWLDSEDA
Sbjct: 180 TVALLSPEDQALIAGFVVNKFRGDPALLAPGLRDLERLTGRRVYGTLPWHPDLWLDSEDA 239

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           L+L GRR+A  GA RVAVVRLPRISNFTDVDA GLEPDLDVVFAS P  L DADL+V+PG
Sbjct: 240 LELQGRRSARPGARRVAVVRLPRISNFTDVDAFGLEPDLDVVFASHPSALADADLVVLPG 299

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGL 360
           TR+TIADLAWLR+RGLDRA++AH AAG+P+LGICGGFQMLGRVIRDP GVEG  +EADGL
Sbjct: 300 TRSTIADLAWLRSRGLDRAVLAHAAAGRPVLGICGGFQMLGRVIRDPHGVEGGTSEADGL 359

Query: 361 GLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMW 420
           GLLD+ET F A+K LRLP GQ    +ASGYEIHHGRIT G    +F GG R G VFGTMW
Sbjct: 360 GLLDIETDFVADKALRLPEGQWEATSASGYEIHHGRITPGPGGDEFPGGVRCGPVFGTMW 419

Query: 421 HGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477
           HG+ EGDALR  FL ETLG+  SG SF  ARE R+DLLGDLVE HLDVDALL LA H
Sbjct: 420 HGAFEGDALRARFLTETLGVPASGASFPKAREDRIDLLGDLVEEHLDVDALLRLAEH 476


>tr|C1YJM9|C1YJM9_NOCDA Tax_Id=446468 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Nocardiopsis dassonvillei subsp.
           dassonvillei DSM 43111]
          Length = 527

 Score =  696 bits (1796), Expect = 0.0
 Identities = 351/477 (73%), Positives = 385/477 (80%), Gaps = 1/477 (0%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGTTSDAGKS +T  LCRAFARRG RVAP+KAQNMSNNSMVC GP G   EIGRAQ
Sbjct: 23  GLLVAGTTSDAGKSVVTTALCRAFARRGARVAPYKAQNMSNNSMVCHGPDGRPAEIGRAQ 82

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAF 122
           WVQALAA A PE AMNPVLLKPG+D RSH VL+G   G+++S++W  GR+ LAE AH A+
Sbjct: 83  WVQALAARAVPEPAMNPVLLKPGTDRRSHAVLLGHPAGDVSSADWEAGRRHLAEAAHAAY 142

Query: 123 DDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTI 182
           DDLA+R+DVVVAEGAGSPAEINLRAGDYVNMGLA HA LP +VVGDIDRGGVFAA +GT+
Sbjct: 143 DDLASRHDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPVVVVGDIDRGGVFAAMYGTV 202

Query: 183 ALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALD 242
            LL   DQ LVAGFVVNKFRGD  LL PGL DLE +TGR+V+GTLPW   LWLDSEDALD
Sbjct: 203 GLLEPADQELVAGFVVNKFRGDPGLLRPGLEDLERLTGRRVYGTLPWDPGLWLDSEDALD 262

Query: 243 LTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPGTR 302
           L GRR       RVAVVRLPRISNFTDVDALGLEP LDVVFAS PR + DADL+V+PGTR
Sbjct: 263 LEGRRTRGGAGLRVAVVRLPRISNFTDVDALGLEPGLDVVFASGPRDVADADLVVLPGTR 322

Query: 303 ATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEG-PVAEADGLG 361
           +T+ADLAWLR+RGLDRA++ H   G+PLLGICGGFQMLGR + D DGVE  P A ADGLG
Sbjct: 323 STLADLAWLRSRGLDRAIVEHARRGRPLLGICGGFQMLGRTVTDADGVEAEPGARADGLG 382

Query: 362 LLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMWH 421
           LLD  T F A+K LRLP G+ LG  A GYEIHHGR+T G  A+ F GGAR G VFGTMWH
Sbjct: 383 LLDARTDFTADKTLRLPSGEALGAPAHGYEIHHGRVTVGGGAEGFPGGARAGNVFGTMWH 442

Query: 422 GSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARHG 478
           GSLEGDA R AFL E LG   SG  F+AARERRLDLL DL E HLDVDALLALAR G
Sbjct: 443 GSLEGDAFRAAFLAEALGCAPSGVRFAAARERRLDLLADLAEEHLDVDALLALAREG 499


>tr|A1SJM8|A1SJM8_NOCSJ Tax_Id=196162 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Nocardioides sp.]
          Length = 495

 Score =  668 bits (1723), Expect = 0.0
 Identities = 344/485 (70%), Positives = 389/485 (80%), Gaps = 11/485 (2%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M G+LVAGT+SDAGKS +T GLCR+ AR GV VAPFKAQNMSNNSMVC      G EIGR
Sbjct: 1   MSGILVAGTSSDAGKSVVTTGLCRSLARAGVHVAPFKAQNMSNNSMVCAD----GAEIGR 56

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQA+AANA PEAAMNPVLLKPGSD RSHVV+MGR  G L + ++ EGR+ LA  A+ 
Sbjct: 57  AQWVQAVAANAEPEAAMNPVLLKPGSDLRSHVVVMGRPGGTLGADDFAEGREPLAAAAYA 116

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFDDLA+RYDVVVAEGAGSPAEINLR+GD+VNMGLA HA LPT+VVGDIDRGG+ AA FG
Sbjct: 117 AFDDLASRYDVVVAEGAGSPAEINLRSGDFVNMGLARHAGLPTVVVGDIDRGGLLAAMFG 176

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL   DQ L+AGFVVNKFRGDLDLL PGL ++  +TGR V+G LPWH DLW+DSED 
Sbjct: 177 TVALLEPADQRLLAGFVVNKFRGDLDLLRPGLEEVARLTGRPVYGVLPWHPDLWMDSEDT 236

Query: 241 LDLTGRRAA-STGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVP 299
           L + GR+A     A +VAVVRLPRISN TDVDALG+EP LDVVFA+DPR L DADL+V+P
Sbjct: 237 LAVAGRQARDGRAALKVAVVRLPRISNVTDVDALGIEPSLDVVFATDPRALSDADLVVLP 296

Query: 300 GTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEG-PVAEAD 358
           GTRATIADLAWLR RGLDRA+ AH AAG+P+LGICGGFQMLGR + DP GVEG P AE +
Sbjct: 297 GTRATIADLAWLRERGLDRAVHAHAAAGRPVLGICGGFQMLGRSVSDPGGVEGQPGAEVE 356

Query: 359 GLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGT 418
           GL LLDV T F A KVLRL RG  LG + +GYEIHHGR+T G  A++FLGGAR+G V GT
Sbjct: 357 GLALLDVRTDFSAVKVLRLSRGLALGASTAGYEIHHGRVTRGAGAEEFLGGAREGHVLGT 416

Query: 419 MWHGSLEGDALREAFLRETLGLTG-----SGTSFSAARERRLDLLGDLVERHLDVDALLA 473
           MWHGSLEGDA R AFL E   LTG     SG SF+AARE R++LL DLVE HLDV A+ A
Sbjct: 417 MWHGSLEGDAFRTAFLTEVARLTGHVWEPSGVSFAAAREGRMELLADLVEEHLDVAAIAA 476

Query: 474 LARHG 478
           LA  G
Sbjct: 477 LASEG 481


>tr|A1SKP7|A1SKP7_NOCSJ Tax_Id=196162 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Nocardioides sp.]
          Length = 476

 Score =  652 bits (1681), Expect = 0.0
 Identities = 344/479 (71%), Positives = 382/479 (79%), Gaps = 18/479 (3%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M GLLVAGTTSDAGKS +T GLCRAFARRGVRVAP+KAQNMSNNSMVC GP     EIGR
Sbjct: 1   MSGLLVAGTTSDAGKSVVTTGLCRAFARRGVRVAPYKAQNMSNNSMVCAGPDERLAEIGR 60

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQWVQALAA ATPE AMNPVLLKPGSD RSHVVL+GR  GE++S++W EGR+ LAE AH 
Sbjct: 61  AQWVQALAARATPEPAMNPVLLKPGSDRRSHVVLLGRPAGEVSSASWEEGRRHLAEAAHE 120

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           AFDDLA+RYDV+VAEGAGSPAEINLRAGDYVNMGLA HA LPT+VVGDIDRGGVFAA  G
Sbjct: 121 AFDDLASRYDVIVAEGAGSPAEINLRAGDYVNMGLARHAALPTVVVGDIDRGGVFAALHG 180

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL+ +DQALVAGFV+NKFRGDL LL+PGL  L   TGR  +G LPW   LWLDSEDA
Sbjct: 181 TVALLAPDDQALVAGFVMNKFRGDLSLLSPGLEMLRLATGRPTYGVLPWDPSLWLDSEDA 240

Query: 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LDL GRR+A +GA RVAVVRLPRISNFTD+DALGLEPDLDVVFAS  R L DADL+V+PG
Sbjct: 241 LDLDGRRSAGSGAKRVAVVRLPRISNFTDLDALGLEPDLDVVFASSARDLADADLVVLPG 300

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEG-PVAEADG 359
           TRAT+ADLAW+RARGLD A++AH  AG+ +LGICGG QMLGR I DP G+EG P     G
Sbjct: 301 TRATVADLAWMRARGLDGAIIAHADAGRAVLGICGGCQMLGRTITDPAGIEGDPGTVVAG 360

Query: 360 LGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTM 419
           LGLL   TTFGA+KVLR+          +GYEIHHGRI          G   DG V GTM
Sbjct: 361 LGLLPHTTTFGADKVLRVHE-------PAGYEIHHGRIA---------GRTEDGLVSGTM 404

Query: 420 WHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARHG 478
            HGSLE DA R A+L+  LG+T S  SF AAR+ R+DLLGDLVE+HLDVDALLALA  G
Sbjct: 405 VHGSLEDDAHRAAYLQRVLGVT-SRASFPAARDARIDLLGDLVEQHLDVDALLALAVSG 462


>tr|C7MTR3|C7MTR3_SACVD Tax_Id=471857 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);[Saccharomonospora
           viridis]
          Length = 498

 Score =  645 bits (1664), Expect = 0.0
 Identities = 333/482 (69%), Positives = 383/482 (79%), Gaps = 12/482 (2%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGK+ +  GLCRAFARRG++VAPFKAQNMSNNSMVC      G EIGRAQW
Sbjct: 11  LLVAGTTSDAGKTLVATGLCRAFARRGLKVAPFKAQNMSNNSMVCAD----GAEIGRAQW 66

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           VQALAA   PEAAMNPVLLKPG D RSHVV++GR  GEL S+ + EGR  LA+ A+ A+ 
Sbjct: 67  VQALAAGVEPEAAMNPVLLKPGGDRRSHVVVLGRPAGELGSAEFPEGRAHLADAAYAAYR 126

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
           DL++R+D+VV EGAGSPAEINLRAGDYVNMGLA H ++PT++VGDIDRGGVFAAF+GT+A
Sbjct: 127 DLSSRFDLVVCEGAGSPAEINLRAGDYVNMGLARHDDIPTVLVGDIDRGGVFAAFYGTVA 186

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           LL   DQAL+AGFVVNKFRGD  LLAPGLR LE +TGR+V+GT+PW  D+WLDSED L L
Sbjct: 187 LLEPADQALIAGFVVNKFRGDDTLLAPGLRRLEELTGRRVYGTVPWSPDVWLDSEDTLGL 246

Query: 244 TGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPGTRA 303
            GR  A  GA RV V+RLPRISN TD+DALGLEP ++VVF +DP  L DADL+V+PGTRA
Sbjct: 247 AGRSPAEEGALRVVVIRLPRISNVTDLDALGLEPGVEVVFTADPYDLADADLVVLPGTRA 306

Query: 304 TIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVE--GPVAEADGLG 361
           T+ADLAWLR+RGLDRA++ H  AG+ +LGICGGFQMLGR + DP+GVE  GPV+   GLG
Sbjct: 307 TVADLAWLRSRGLDRAVVRHAEAGRAVLGICGGFQMLGRHVHDPEGVEASGPVS-VPGLG 365

Query: 362 LLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMWH 421
           LL VETTF  +K LR  RG   GV A GYEIHHGRIT     ++FLGGAR G+V GTMWH
Sbjct: 366 LLPVETTFSPDKTLRRSRGTAFGVEAFGYEIHHGRITRDVGVEEFLGGARVGRVLGTMWH 425

Query: 422 GSLEGDALREA---FLRETLG--LTGSGTSFSAARERRLDLLGDLVERHLDVDALLALAR 476
           GSLE DALR A   F  E  G     SG  F+ +RE RLDLLGDLVERHLDVDALLALA+
Sbjct: 426 GSLESDALRTAVLNFAAEARGRSFAASGVDFARSREARLDLLGDLVERHLDVDALLALAQ 485

Query: 477 HG 478
           HG
Sbjct: 486 HG 487


>tr|C1WP45|C1WP45_9ACTO Tax_Id=479435 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Kribbella flavida DSM 17836]
          Length = 486

 Score =  561 bits (1445), Expect = e-158
 Identities = 299/484 (61%), Positives = 344/484 (71%), Gaps = 18/484 (3%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M  LL+AGTTSDAGK+T+  GLCR  AR+GVRVAPFKAQNMSNNSMVC      G EIGR
Sbjct: 1   MNSLLIAGTTSDAGKTTVVTGLCRWLARQGVRVAPFKAQNMSNNSMVCAD----GAEIGR 56

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQW+QA+AA A PEAAMNPVLLKPGSD RSHVVLMG  WGEL +  +   R  LA+ A  
Sbjct: 57  AQWIQAVAAGAAPEAAMNPVLLKPGSDRRSHVVLMGEPWGELTARGFLTERAELAKAAFA 116

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           A+DDLA+RYDVVV+EGAGSP EINLR  DYVNMGLA HA+ P +VVGDIDRGGVFA+ FG
Sbjct: 117 AYDDLASRYDVVVSEGAGSPTEINLRQSDYVNMGLARHAQAPVVVVGDIDRGGVFASMFG 176

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALLS +DQ LV+GFVVNKFRGD+ LL PG+  L GVTGR  +G LPW  DLWLDSEDA
Sbjct: 177 TVALLSTDDQRLVSGFVVNKFRGDVSLLRPGIDMLTGVTGRPTYGVLPWLPDLWLDSEDA 236

Query: 241 LDLTGRRAASTG-AHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVP 299
           LDL  RR ++ G    +AVVR PRISNFTD+DAL +EP   V F + P  + DADL+V+P
Sbjct: 237 LDLPARRTSTDGDVLTIAVVRFPRISNFTDLDALAVEPTTSVFFTAGPAEVRDADLVVLP 296

Query: 300 GTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADG 359
           G+RAT ADLAWLR  GL  A+ A VAAG+P+LGICGG+QMLG +I DP GVE       G
Sbjct: 297 GSRATTADLAWLREHGLADAVQARVAAGRPVLGICGGYQMLGGMIDDPYGVESG-GRHTG 355

Query: 360 LGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTM 419
           LGLL V T F A KVL  P         + YEIHHG +     A  F GG R G V+GT+
Sbjct: 356 LGLLPVATEFAAAKVLARP-------ARTAYEIHHGVVAQTAEADDFPGGCRSGVVWGTI 408

Query: 420 WHGSLEGDALREAFLRETLGLTG----SGT-SFSAARERRLDLLGDLVERHLDVDALLAL 474
           WHG L+ DA R  FL E   LTG     GT SF+  RERRLD L D ++ HLD  AL+ L
Sbjct: 409 WHGLLDDDAARHRFLGEIAALTGKPAPDGTVSFAGLRERRLDRLADAIDEHLDTAALMTL 468

Query: 475 ARHG 478
              G
Sbjct: 469 IEKG 472


>tr|Q47T70|Q47T70_THEFY Tax_Id=269800 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Thermobifida fusca]
          Length = 501

 Score =  534 bits (1376), Expect = e-150
 Identities = 289/485 (59%), Positives = 336/485 (69%), Gaps = 10/485 (2%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGT+SDAGKS +T+ LCRA AR G++VAPFKAQNMSNNSMV  GP G G EI RAQ
Sbjct: 6   GLLVAGTSSDAGKSLVTSALCRALARHGIKVAPFKAQNMSNNSMVVPGPDGTGAEISRAQ 65

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAF 122
           WVQALAA A PE AMNPVLLKP SD  SHVVL GR +G LA+  +   R VLAE A+ A 
Sbjct: 66  WVQALAARAEPETAMNPVLLKPSSDRGSHVVLRGRPFGRLAAGEFAGTRAVLAEAAYAAL 125

Query: 123 DDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTI 182
            +L +RYDVVV EGAG  AEINLRA DY+NMGLA  A+LP IV+GDI+RGGVFA+ +G++
Sbjct: 126 AELRSRYDVVVCEGAGGVAEINLRAHDYINMGLARAADLPVIVIGDINRGGVFASLYGSL 185

Query: 183 ALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALD 242
           ALL   DQALVAGFV+NKFRGD  LL P L+ LE +TGR V G LPW  +LWL+SED+L 
Sbjct: 186 ALLDPADQALVAGFVINKFRGDPSLLDPALKTLEDLTGRPVLGVLPWQQNLWLESEDSLA 245

Query: 243 LTGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300
           LT R   S G    RVAVVRLPRI N TDVDALG+EP L V F + PR L  AD++V+P 
Sbjct: 246 LTAREDGSAGTPVLRVAVVRLPRIGNTTDVDALGVEPGLRVDFVTSPRLLASADIVVLPD 305

Query: 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE-ADG 359
           TRA + DL WLR+RGL  A+  H   G  +LGI GGFQMLGR I D +GVEGP      G
Sbjct: 306 TRAVLTDLEWLRSRGLADAIANHARHGGTVLGIGGGFQMLGRTIVDAEGVEGPAGRTVAG 365

Query: 360 LGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTM 419
           L LLD+ET F   + L    G   G+   GY+ H+ RI  GD  + F GG R+G VFGTM
Sbjct: 366 LSLLDLETVFTRNQTLNYSSGTWQGIPVGGYQSHYSRIQTGD-GEAFPGGLRNGSVFGTM 424

Query: 420 WHGSLEGDALREAFL---RETLGLTGS---GTSFSAARERRLDLLGDLVERHLDVDALLA 473
           WHGSLE DA R A+L    E  G  GS      F+  R+  LD LGDL E HLD+DA+L 
Sbjct: 425 WHGSLEHDAFRGAWLAAAAENAGYDGSEYGQVCFAEVRDAYLDRLGDLAEEHLDMDAVLR 484

Query: 474 LARHG 478
           L   G
Sbjct: 485 LITEG 489


>tr|C4RPI9|C4RPI9_9ACTO Tax_Id=219305 SubName: Full=Cobyric acid
           synthase cobQ;[Micromonospora sp. ATCC 39149]
          Length = 514

 Score =  517 bits (1331), Expect = e-144
 Identities = 293/499 (58%), Positives = 331/499 (66%), Gaps = 25/499 (5%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGTTSDAGKS LTAG+CR   RRGV+VAPFKAQNMSNNS V  GP G G EIGRAQ
Sbjct: 4   GLLVAGTTSDAGKSVLTAGICRWLRRRGVKVAPFKAQNMSNNSAVVVGPDGRGGEIGRAQ 63

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAF 122
            +QA A     +   NPVLLKPGSD  S VVL+G +   + + N+   R  LAE A  + 
Sbjct: 64  AMQAAACGVAADLRFNPVLLKPGSDRSSQVVLLGEAVDTVTAGNYHALRPRLAEAAFASL 123

Query: 123 DDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTI 182
            +L   Y+VVV EGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFA+ FGT+
Sbjct: 124 AELREAYEVVVCEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFASMFGTV 183

Query: 183 ALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDAL- 241
           ALL   DQALVAGFV+NKFRGD  LL PGL  L  VTGR  +G LPWH DLWLD+ED+L 
Sbjct: 184 ALLDPADQALVAGFVINKFRGDRGLLQPGLDMLTRVTGRPTYGVLPWHLDLWLDAEDSLA 243

Query: 242 --DLTGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIV 297
              + GR AA  G     VAVVRLPRISN TDV+AL  EP + V    +P  L  AD++V
Sbjct: 244 YGRVLGRPAAPHGTDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAADIVV 303

Query: 298 VPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEA 357
           +PG+++T+ADLAWLR  GL  A+ AH AAGKPLLGICGGFQMLGR + DP  VE      
Sbjct: 304 LPGSKSTVADLAWLRRTGLADAVAAHAAAGKPLLGICGGFQMLGRAVHDP--VESRAGSV 361

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQG---LGVTASGYEIHHGRITAGDAAQQFL------- 407
            GLGLL VE TF A K +R   G      GV   GYEIHHG +++ D A   L       
Sbjct: 362 AGLGLLPVEVTFAARKTVRQAAGTAAADAGVPVRGYEIHHGYVSSADPALPPLLSYDDGT 421

Query: 408 -GGARDGQVFGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLLG 459
             GA  G V GT WHG+ E DA R  FL +   L G         TSF+AARER LDLLG
Sbjct: 422 GEGAVLGAVCGTHWHGAFESDAFRRRFLTDAARLAGRTGFRVAPDTSFAAARERSLDLLG 481

Query: 460 DLVERHLDVDALLALARHG 478
           DLVE HLD  AL  L   G
Sbjct: 482 DLVEEHLDTAALWRLIECG 500


>tr|A4XAN6|A4XAN6_SALTO Tax_Id=369723 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Salinispora tropica]
          Length = 521

 Score =  513 bits (1322), Expect = e-143
 Identities = 291/497 (58%), Positives = 330/497 (66%), Gaps = 23/497 (4%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLV GTTSDAGKS LTAG+CR   R+GVRVAPFKAQNMSNNS V  GP G G EIGRAQ
Sbjct: 4   GLLVTGTTSDAGKSVLTAGICRWLHRQGVRVAPFKAQNMSNNSAVVVGPDGHGGEIGRAQ 63

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAF 122
            +QA A    P+   NPVLLKPGSD  S VVL+G +   L +  + + R  LAETA+ A 
Sbjct: 64  AMQAAACGLAPDLRFNPVLLKPGSDRSSQVVLLGEAVDTLTTDTFRQLRPRLAETAYAAL 123

Query: 123 DDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTI 182
            +L   YDVV+ EGAGSP EINLRAGDYVNMGLA HA+LP IVVGDIDRGGVFA+ FGT+
Sbjct: 124 AELRTSYDVVICEGAGSPTEINLRAGDYVNMGLARHADLPAIVVGDIDRGGVFASMFGTV 183

Query: 183 ALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDAL- 241
           ALL   DQALVAGFV+NKFRGD  LLAPGL  L  VTGR  +G LPW  DLWLD+ED+L 
Sbjct: 184 ALLEPADQALVAGFVINKFRGDRGLLAPGLDMLRQVTGRPTYGVLPWALDLWLDAEDSLA 243

Query: 242 --DLTGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIV 297
              + GR AA  G+    VAVVRLPRISN TDV+AL  EP + V    +P  L  ADL+V
Sbjct: 244 YGRVLGRPAAPRGSDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAADLVV 303

Query: 298 VPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEA 357
           +PG+++T+ADLAWLR  GL  A++AH AAG+PLLGICGGFQMLGR I DP  VE      
Sbjct: 304 LPGSKSTVADLAWLRQNGLADAVLAHAAAGRPLLGICGGFQMLGRRIHDP--VESGQGSV 361

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGL-GVTASGYEIHHGRITAG--DAAQQFL------G 408
            GLGLL VE TF   K +R   G G  GV   GYEIHHG ++A   D A  F        
Sbjct: 362 PGLGLLPVEVTFKPSKTVRQSAGTGWDGVPVRGYEIHHGYVSAAAPDLAPLFTYADGTGE 421

Query: 409 GARDGQVFGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLLGDL 461
           G   G V+GT WHG+ E D  R  FL E     G         TSF+ ARER LDLLGDL
Sbjct: 422 GVAAGAVYGTHWHGAFESDGFRRRFLTEVARQAGRPGFRAAPDTSFAGARERSLDLLGDL 481

Query: 462 VERHLDVDALLALARHG 478
           VE HLD   L  L   G
Sbjct: 482 VEEHLDTAVLWRLIDTG 498


>tr|A8M1Q8|A8M1Q8_SALAI Tax_Id=391037 SubName: Full=Cobyric acid
           synthase CobQ;[Salinispora arenicola]
          Length = 575

 Score =  510 bits (1314), Expect = e-142
 Identities = 292/499 (58%), Positives = 333/499 (66%), Gaps = 27/499 (5%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGTTSDAGKS LTAG+CR   RRGVRVAPFKAQNMSNNS V  GP G G EIGRAQ
Sbjct: 4   GLLVAGTTSDAGKSVLTAGICRWLHRRGVRVAPFKAQNMSNNSAVVVGPDGRGGEIGRAQ 63

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAF 122
            +QA A    P+   NPVLLKPGSD  S VVL+G +   L +  + + R  LA+TA+ A 
Sbjct: 64  AMQAAACGLAPDLRFNPVLLKPGSDRTSQVVLLGEAVDTLTTGTFRQLRPRLADTAYAAL 123

Query: 123 DDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTI 182
            DL A +DVV+ EGAGSPAEINLRAGDYVNMGLA HA LP IVVGDIDRGGVFA+ FGT+
Sbjct: 124 ADLRATHDVVICEGAGSPAEINLRAGDYVNMGLARHAGLPAIVVGDIDRGGVFASMFGTV 183

Query: 183 ALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDAL- 241
           ALL   DQALVAGFV+NKFRGD  LLAPGL  L  VTGR  +G LPW  DLWLD+ED+L 
Sbjct: 184 ALLEPADQALVAGFVINKFRGDPSLLAPGLDMLRQVTGRPTYGVLPWALDLWLDAEDSLA 243

Query: 242 --DLTGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIV 297
              + GR AA  G+    VAVVRLPRISN TDV+AL  EP + V    +P  L  ADL+V
Sbjct: 244 YGRVLGRPAAPRGSDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAADLVV 303

Query: 298 VPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEA 357
           +PG+++T+ADL WLR  GL  A++AH AAG+PLLG+CGGFQMLGR+I DP  VE      
Sbjct: 304 LPGSKSTVADLDWLRQSGLADAVLAHAAAGRPLLGVCGGFQMLGRLIHDP--VESRRGSV 361

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTA---SGYEIHHGRITAG--DAAQQFL----- 407
            GLGLL VE TF   K +R  R  G+G  A    GYEIHHG ++A   D A  F      
Sbjct: 362 PGLGLLPVEVTFDPCKTVR--RSAGIGWDAEPVGGYEIHHGYVSAAAPDLAPLFAYHDGT 419

Query: 408 -GGARDGQVFGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLLG 459
             GA  G V+GT WHG+ E D  R  FL       G         TSF+ ARER LDLLG
Sbjct: 420 GEGAVAGSVYGTHWHGAFESDGFRRRFLARVARQAGRHGFQVAPDTSFAGARERSLDLLG 479

Query: 460 DLVERHLDVDALLALARHG 478
           DLVE HLD   L  L   G
Sbjct: 480 DLVEEHLDTAGLWRLIESG 498


>tr|C8XIY4|C8XIY4_NAKMY Tax_Id=479431 SubName: Full=Cobyric acid
           synthase CobQ;[Nakamurella multipartita]
          Length = 486

 Score =  504 bits (1298), Expect = e-140
 Identities = 272/484 (56%), Positives = 322/484 (66%), Gaps = 17/484 (3%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLL+AGT+SDAGKS +TAG+CR  AR+G+RVAPFKAQNMSNNSMVC      G EIGRAQ
Sbjct: 10  GLLIAGTSSDAGKSLVTAGICRFLARQGLRVAPFKAQNMSNNSMVCAD----GSEIGRAQ 65

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAF 122
           ++QA AA A PE+AMNPVLLKPGSD RS VV+ GR  G L S  +  GR+ LA+ A  A+
Sbjct: 66  YLQAQAAGAVPESAMNPVLLKPGSDRRSFVVVRGRPAGTLESGEFASGRRHLAQAAFAAY 125

Query: 123 DDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTI 182
            +LA RYDV+V EGAGSP EINLRAGDYVNMGLA    LP +VVGDIDRGGVFA+ +GT+
Sbjct: 126 RELAGRYDVIVCEGAGSPTEINLRAGDYVNMGLAQEFSLPVVVVGDIDRGGVFASLYGTV 185

Query: 183 ALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALD 242
           ALL A DQAL+ G ++NKFRGD+DLL PGL  +  +TG  V G LPW  ++WLD ED L 
Sbjct: 186 ALLDAADQALIRGLIINKFRGDVDLLRPGLDRIAQLTGVPVLGVLPWLTEVWLDGEDTLQ 245

Query: 243 LTGRRAASTGAH----RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVV 298
           + GR  A  G      RVA +R PR+SN TD+DAL  EP ++V   +DP  +  ADL+V+
Sbjct: 246 V-GRWGAPIGGPEPRLRVAALRFPRLSNVTDLDALACEPGVEVTMTADPGTIRAADLVVL 304

Query: 299 PGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEAD 358
           PG+RAT+ADL WL A GL  A+      G P+LGICGGFQML R I DP  VE       
Sbjct: 305 PGSRATVADLTWLHASGLADAVRQAAGRGTPVLGICGGFQMLARTIDDP--VESGAGPVS 362

Query: 359 GLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHG--RITAGDAAQQFLGGARDGQVF 416
           GLGLL V+  F  +K L  P G   G    GYEIHHG   +  G   + FLGG R G V+
Sbjct: 363 GLGLLPVDVAFAPDKRLGTPAGDWQGHQVRGYEIHHGVATVAPGGGDESFLGGVRVGSVW 422

Query: 417 GTMWHGSLEGDALREAFLRET----LGLTGSGTSFSAARERRLDLLGDLVERHLDVDALL 472
           GTMWHG+ E D  R A+LR           +   F A RE  LD L D V  HLD DALL
Sbjct: 423 GTMWHGAFENDDFRRAWLRTATEGRFHADAAAPGFGARREAMLDRLADAVAEHLDTDALL 482

Query: 473 ALAR 476
           AL R
Sbjct: 483 ALTR 486


>tr|C0UBE6|C0UBE6_9ACTO Tax_Id=526225 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Geodermatophilus obscurus DSM 43160]
          Length = 511

 Score =  498 bits (1281), Expect = e-139
 Identities = 272/486 (55%), Positives = 321/486 (66%), Gaps = 17/486 (3%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS +TAG+CR   R+GV VAPFKAQNMSNNSMV   P GA  EIGRAQ 
Sbjct: 15  LLVAGTTSDAGKSVVTAGICRWLVRQGVSVAPFKAQNMSNNSMVT--PDGA--EIGRAQV 70

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA AA   PEAAMNPVLLKPG +  S VV++G +  ++ + ++   +  L E    + +
Sbjct: 71  MQAAAARVEPEAAMNPVLLKPGGEDSSQVVVLGHAVADVTALSYRPMKAALMEQVLASLE 130

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
           DL +R+DVVV EGAGSP EINLRA D  NMGLA  A LP +VVGDIDRGGVF A +GT+A
Sbjct: 131 DLRSRFDVVVCEGAGSPTEINLRADDIANMGLATAAGLPVVVVGDIDRGGVFPALYGTVA 190

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           L+   DQ LVAGF+VNKFRGD+ LL PGL  L  +TGR   G LPW     +D ED+L +
Sbjct: 191 LMPPADQRLVAGFLVNKFRGDVRLLGPGLEQLTALTGRPTLGVLPWLPGAAVDVEDSLGV 250

Query: 244 TGRRAASTGAH-----RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVV 298
               + +   H     RVAV RLPR+SNFTD+DAL  EP + V +A+ P  LGDADL+V+
Sbjct: 251 PTGASPTGPPHGEEVLRVAVARLPRLSNFTDLDALAAEPGVLVRYATSPEELGDADLVVL 310

Query: 299 PGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEAD 358
           PGTRAT+ADL WLRA GL  A+  H AAG+P+LG+CGG QML R I   D VE       
Sbjct: 311 PGTRATVADLGWLRATGLADAVARHAAAGRPVLGVCGGSQMLARTI--TDDVESRAGTVP 368

Query: 359 GLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGT 418
           GLGLL  +  F  EK L  P G   G    GYEIHHG +   DAA++FL GAR G VFGT
Sbjct: 369 GLGLLPADVRFAPEKTLGRPVGTAFGQEVRGYEIHHGVVIVDDAAERFLDGARAGSVFGT 428

Query: 419 MWHGSLEGDALREAFLRETLGLTG------SGTSFSAARERRLDLLGDLVERHLDVDALL 472
            WHG+LEGD  R AFL E   + G        T F+A RERRLD LGDLV  H D DAL 
Sbjct: 429 TWHGALEGDGFRRAFLTEVARVAGRRFVAAPDTDFAAVRERRLDALGDLVAEHADTDALW 488

Query: 473 ALARHG 478
            L   G
Sbjct: 489 RLVEDG 494


>tr|D1A9H5|D1A9H5_THECU Tax_Id=471852 SubName: Full=Cobyric acid
           synthase CobQ;[Thermomonospora curvata DSM 43183]
          Length = 501

 Score =  493 bits (1269), Expect = e-137
 Identities = 279/486 (57%), Positives = 313/486 (64%), Gaps = 17/486 (3%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS LTAGLCR   R+GV+VAPFKAQNMS NSMV       G EIGRAQ 
Sbjct: 5   LLVAGTTSDAGKSVLTAGLCRWLVRQGVKVAPFKAQNMSLNSMVTAD----GAEIGRAQA 60

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA AA   P A MNP+LLKPG D RS VVL+GR   E+ +  +   R  L   A  +  
Sbjct: 61  MQAQAARIEPTAHMNPILLKPGGDRRSQVVLLGRPVAEVDALGYGAHRDRLRRAALESLA 120

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L A YDVV+ EGAGSPAEINLRAGD  NMGLA  A LP +VVGDIDRGGVFAA +GT+ 
Sbjct: 121 HLRAEYDVVICEGAGSPAEINLRAGDIANMGLARAAGLPVLVVGDIDRGGVFAALYGTVG 180

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           LL   DQAL+AGFV+NKFRG  +LL PGLR L  +TGR V+G LPW   L LD ED+L L
Sbjct: 181 LLEPADQALIAGFVINKFRGAPELLEPGLRMLRDLTGRPVYGVLPWLDGLRLDVEDSLGL 240

Query: 244 TGRRAASTGAH-----RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVV 298
            G  AA+   H     RVAVVRLPRISNFTDVDAL  EP + V +A+ P  L DADL+V+
Sbjct: 241 DGPPAAAGPPHGAETLRVAVVRLPRISNFTDVDALACEPGVTVRYATAPGELADADLVVL 300

Query: 299 PGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEAD 358
           PG+RAT+ADLAWLR RGL   + A    G+P+LGICGG+QML   I   D VE       
Sbjct: 301 PGSRATVADLAWLRERGLADQIAARARRGRPVLGICGGYQMLAEEI--VDEVESGAGSVP 358

Query: 359 GLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGT 418
           GLGLL V   F   K LR P G   G     YEIHHG  T    A+ FL G R G V+GT
Sbjct: 359 GLGLLPVRVEFARHKTLRRPVGTAYGHPVRAYEIHHGAATVTGPAEPFLDGCRVGAVWGT 418

Query: 419 MWHGSLEGDALREAFLRETLGLTG------SGTSFSAARERRLDLLGDLVERHLDVDALL 472
            WHG+LE D  R  FLR      G       G SF A RE RLD LGDLVERHLD  AL 
Sbjct: 419 TWHGALESDGFRREFLRRVAEAAGRDFTPAPGVSFGALREARLDALGDLVERHLDTAALW 478

Query: 473 ALARHG 478
            L   G
Sbjct: 479 RLIERG 484


>tr|C7QGK0|C7QGK0_CATAD Tax_Id=479433 SubName: Full=Cobyric acid
           synthase CobQ;[Catenulispora acidiphila]
          Length = 529

 Score =  493 bits (1268), Expect = e-137
 Identities = 277/508 (54%), Positives = 335/508 (65%), Gaps = 35/508 (6%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPG----------- 52
           LLVAGTTSDAGKS +TAG+CR  AR+GVRVAPFKAQNMSNNSMV    G           
Sbjct: 11  LLVAGTTSDAGKSLITAGICRWLARQGVRVAPFKAQNMSNNSMVVGVAGAANAAHGATGA 70

Query: 53  --GAGVEIGRAQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEG 110
             G G EIGRAQ +QA AA   PE AMNPVLLKPGSD  S VVL+G+ + E +++++ E 
Sbjct: 71  TPGVGAEIGRAQVMQAQAAGVEPEVAMNPVLLKPGSDRTSQVVLLGQVFAEASATSYQEL 130

Query: 111 RQVLAETAHRAFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDID 170
           +  L E    ++ DL +R+DVV+ EGAGSP EINLR GD VNMGLA    +P +VVGDID
Sbjct: 131 KPRLREAVLASYQDLKSRFDVVICEGAGSPTEINLRDGDLVNMGLAQPLGMPVVVVGDID 190

Query: 171 RGGVFAAFFGTIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWH 230
           RGGVFAAF GT+ALL A DQ LV+GF++NKFRGD  LL PGLR +E  TGR VFG +PW 
Sbjct: 191 RGGVFAAFHGTVALLDAADQKLVSGFIINKFRGDPSLLTPGLRQIEDFTGRPVFGVVPWL 250

Query: 231 ADLWLDSEDALDL----TGRR--AASTGAH-RVAVVRLPRISNFTDVDALGLEPDLDVVF 283
             + LD+EDAL +     G R  A   GA  RVAVVR PR+SNFTDVDAL +EP +DV F
Sbjct: 251 PGIRLDAEDALPIEAYAAGARDGALDGGARLRVAVVRFPRVSNFTDVDALAIEPGVDVEF 310

Query: 284 ASDPRGLGDADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRV 343
            +    +  ADL+V+PGT++T+ADLAWLR RGL+ AL    A G+P+LGICGG+QMLG V
Sbjct: 311 TASAAAVESADLVVLPGTKSTVADLAWLRERGLEPALAKRAAEGRPILGICGGYQMLGTV 370

Query: 344 IRDPDGVEGPVAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHG--RITAG- 400
           I D   VE       GLGLL V T F   K L  P G GLG    GYEIH+G  R+  G 
Sbjct: 371 IEDE--VESRRGTVAGLGLLPVRTVFDPVKTLTRPTGFGLGEPVGGYEIHNGQVRVEGGE 428

Query: 401 ----DAAQQFLGGARDGQVFGTMWHGSLEGDALREAFLRETLGLTG------SGTSFSAA 450
               DA+   L G +DG V+GT+WHG+LE D  R A+L E   + G         SF+A 
Sbjct: 429 SLFTDASGAALEGCQDGAVWGTIWHGALESDGFRRAYLAEVARVCGLRFEPDPDVSFAAE 488

Query: 451 RERRLDLLGDLVERHLDVDALLALARHG 478
           RE++LD LGD VE ++D + L  L   G
Sbjct: 489 REKQLDRLGDAVEEYVDTERLWRLIEDG 516


>tr|C4DVK9|C4DVK9_9ACTO Tax_Id=446470 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Stackebrandtia nassauensis DSM 44728]
          Length = 512

 Score =  487 bits (1253), Expect = e-135
 Identities = 276/496 (55%), Positives = 325/496 (65%), Gaps = 27/496 (5%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLV GT SD+GKST+ AGLCR  ARRGVRVAPFKAQNMSNNS V    G    EIGRAQ 
Sbjct: 10  LLVTGTCSDSGKSTVVAGLCRYLARRGVRVAPFKAQNMSNNSAVTADGG----EIGRAQA 65

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
            QA AA   P+ A NPVLLKPGSD+ S +V+ G+ WG + ++NW   R+ L+     +  
Sbjct: 66  KQAAAAGLEPDVAFNPVLLKPGSDYTSQIVVRGKPWGTIDAANWPRLRRELSGVVAESLT 125

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
           +L +RYDVV+ EGAGSPAEINLRA D VN+GLA  A++PTIVVGDIDRGGVFA+ +GT+A
Sbjct: 126 ELRSRYDVVICEGAGSPAEINLRAHDIVNLGLARTADIPTIVVGDIDRGGVFASLYGTLA 185

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           LL   DQ L+AGFVVNKFRGD+ LL PGL  L  +TGR V+G LPW  DLWLD+ED+L L
Sbjct: 186 LLEPADQRLIAGFVVNKFRGDVGLLRPGLDSLTELTGRPVYGVLPWLVDLWLDAEDSLAL 245

Query: 244 -----TGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
                 GR     G    RVAVVRLPRISN TDV+AL  EP + V   S    L +ADLI
Sbjct: 246 DAGGVLGRPRPPRGEQWLRVAVVRLPRISNATDVEALAAEPGVRVRITSGAADLAEADLI 305

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PG+++T+ DL WLR  GLD A+ AH  AGKPLLGICGG+QMLGRVIR  D VE     
Sbjct: 306 VIPGSKSTVDDLEWLRDNGLDTAIRAHAEAGKPLLGICGGYQMLGRVIR--DDVESKRGS 363

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGR--ITAGDAAQQFLG-----G 409
             GLGLL  E  F A+K L  P+G    +  SGYEIH+GR  + AG A+   L      G
Sbjct: 364 VPGLGLLPAEFDFAADKTLTHPKGHYGDIPVSGYEIHYGRDTVDAGAASMFRLADGTGEG 423

Query: 410 ARDGQVFGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLLGDLV 462
           AR G V GT WHG+   DA R AFL     L G           F+A RE  LD L DLV
Sbjct: 424 ARLGSVSGTHWHGAFGCDAFRRAFLTGAAALAGRDRFAVDDTVDFAALRESELDALADLV 483

Query: 463 ERHLDVDALLALARHG 478
             HLD+ A+ +L R G
Sbjct: 484 GDHLDMAAITSLIRDG 499


>tr|C4E3Z2|C4E3Z2_STRRS Tax_Id=479432 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Streptosporangium roseum DSM 43021]
          Length = 509

 Score =  486 bits (1250), Expect = e-135
 Identities = 270/487 (55%), Positives = 321/487 (65%), Gaps = 24/487 (4%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS +TAG+CR  AR+GV+VAP+KAQNMS NS V       G EIGRAQ 
Sbjct: 5   LLVAGTTSDAGKSVVTAGICRWLARQGVKVAPYKAQNMSLNSFVTAD----GAEIGRAQA 60

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA A    P A MNP+LLKPGSD RS VV+MGR   ++ +  +++ +  L + A  A +
Sbjct: 61  MQAAACGLEPSADMNPILLKPGSDRRSQVVVMGRPLADVDAMEYWDVKDRLRQVAVDALE 120

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L   YDVVV EGAGSPAEINLR GD  NMGLA  A LP IVVGDIDRGGVFA+ +GT+A
Sbjct: 121 RLRDTYDVVVCEGAGSPAEINLRRGDIANMGLARAASLPVIVVGDIDRGGVFASLYGTVA 180

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           LL   DQAL+AGFV+NKFRG  +LL PGL  +  +TGR+V+G LPW   LWLD ED+L L
Sbjct: 181 LLEPADQALIAGFVINKFRGARELLEPGLDMIRDLTGREVYGVLPWLDGLWLDVEDSLAL 240

Query: 244 TGRRAASTGAH------RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIV 297
             R A            RVAVVRLPRISNFTDVDAL  EP + V F + P  L DADL+V
Sbjct: 241 DNRPAIGARTPYGRQTLRVAVVRLPRISNFTDVDALASEPGVVVRFVTSPAELDDADLVV 300

Query: 298 VPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEA 357
           +PG+RAT++DLAWLRA GL  AL      G+ +LGICGG+QML R I   DGVE      
Sbjct: 301 LPGSRATVSDLAWLRATGLADAL-----RGRVVLGICGGYQMLARTIH--DGVESGAGRV 353

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417
           +GLGLL     F AEK L  P G+  G   + YEIHHG +TA +    FL G R G V+G
Sbjct: 354 EGLGLLPATVEFAAEKTLGRPVGEAYGCRVAAYEIHHGVVTA-EGGDPFLDGCRSGSVWG 412

Query: 418 TMWHGSLEGDALREAFLRETLGLTG------SGTSFSAARERRLDLLGDLVERHLDVDAL 471
           T WHG+LE D  R AFL +   ++G         SF+A RE RLD LGDL+E H+D  AL
Sbjct: 413 TTWHGALENDDFRRAFLADVAAVSGRDFTPAPDVSFAALREERLDALGDLIEHHVDTAAL 472

Query: 472 LALARHG 478
           L L   G
Sbjct: 473 LRLLEGG 479


>sp|Q829J5|COBQ_STRAW Tax_Id=33903 (cobQ)RecName: Full=Cobyric acid
           synthase;[Streptomyces avermitilis]
          Length = 502

 Score =  483 bits (1244), Expect = e-134
 Identities = 274/494 (55%), Positives = 318/494 (64%), Gaps = 27/494 (5%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLL+AGTTSDAGKS +TAG+CR   R+GV+VAPFKAQNMS NS V +     G EIGRAQ
Sbjct: 4   GLLIAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTR----EGAEIGRAQ 59

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQ-VLAETAHRA 121
            +QA AA   P A MNPVLLKPGSD  S VVLMGR  GE+++  +  GRQ  L  T    
Sbjct: 60  AMQAQAARVEPTALMNPVLLKPGSDRSSQVVLMGRPVGEMSARGYHGGRQEALLGTVLDC 119

Query: 122 FDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGT 181
             +L   YD V+ EGAGSPAEINLR  D VNMG+A +A LP +VVGDIDRGGVFA+FFGT
Sbjct: 120 LAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARNARLPVLVVGDIDRGGVFASFFGT 179

Query: 182 IALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDAL 241
           +ALLS EDQ LVAGF+VNKFRGD+ LL PGL  L  +TGR  +G LP+   L +D ED L
Sbjct: 180 VALLSREDQELVAGFLVNKFRGDVSLLEPGLDMLRNLTGRPSYGVLPFQHGLGIDEEDGL 239

Query: 242 DLTGRRAASTGA---------HRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGD 292
            ++ R +    A          RVAV  +P +SNFTDVDAL  EP + V F   P  L D
Sbjct: 240 RVSLRGSVRESAVSSPVGEDILRVAVCAIPLMSNFTDVDALAAEPGVVVRFVDRPEELAD 299

Query: 293 ADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEG 352
           ADL+V+PGTR T+  L WLR RGL  AL    AAG+P+LGICGGFQ+LG  I   D VE 
Sbjct: 300 ADLVVIPGTRGTVKALEWLRERGLAEALRRRAAAGRPVLGICGGFQVLGEHIE--DDVES 357

Query: 353 PVAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHG--RITAGDAAQQFLGGA 410
                +GLGLL V   F  EK L  P G+ LG    GYEIHHG   +T GD    FL G 
Sbjct: 358 RRGHVEGLGLLPVRVRFAREKTLTRPVGEALGEHVEGYEIHHGVADVTGGD---PFLDGC 414

Query: 411 RDGQVFGTMWHGSLEGDALREAFLRETLGLTG------SGTSFSAARERRLDLLGDLVER 464
           R G V+GT WHGSLE D  R AFLRE     G      +GTSF+  RE +LD LGDL+E 
Sbjct: 415 RVGAVWGTHWHGSLESDGFRRAFLREVAAAAGRRFVPAAGTSFAGLREEQLDRLGDLIEE 474

Query: 465 HLDVDALLALARHG 478
           H D DAL  L   G
Sbjct: 475 HADTDALWRLIESG 488


>tr|C9NHQ4|C9NHQ4_9ACTO Tax_Id=591167 SubName: Full=Cobyric acid
           synthase CobQ;[Streptomyces flavogriseus ATCC 33331]
          Length = 538

 Score =  479 bits (1234), Expect = e-133
 Identities = 273/492 (55%), Positives = 313/492 (63%), Gaps = 23/492 (4%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGTTSDAGKS +TAG+CR   RRGV+VAPFKAQNMS NS V +     G EIGRAQ
Sbjct: 4   GLLVAGTTSDAGKSVVTAGICRWLVRRGVKVAPFKAQNMSLNSFVTR----EGAEIGRAQ 59

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQ-VLAETAHRA 121
            +QA AA   P A MNPVLLKPG D  S VVLMGR  GE+++  +  GRQ  L  T    
Sbjct: 60  AMQAQAARVEPSALMNPVLLKPGGDRSSQVVLMGRPVGEMSARGYHGGRQEALLGTVTDC 119

Query: 122 FDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGT 181
            + L   YD V+ EGAGSPAEINLR  D VNMG+A  A  P +VVGDIDRGGVFA+FFGT
Sbjct: 120 LEQLRGTYDAVICEGAGSPAEINLRRTDIVNMGIARAARFPVLVVGDIDRGGVFASFFGT 179

Query: 182 IALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDAL 241
            ALLS EDQ+LVAG++VNKFRGD+ LL PGL  L G+TGR+ FG LP+   L +D ED L
Sbjct: 180 TALLSPEDQSLVAGYLVNKFRGDVSLLEPGLDMLLGLTGRRTFGVLPYAHGLGIDEEDGL 239

Query: 242 DLTGRRAA---------STGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGD 292
            ++ R A               RVAV  +P +SNFTDVDAL  EP + V F      L D
Sbjct: 240 RVSMRGAVRESVVAPPHGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRAEELVD 299

Query: 293 ADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEG 352
           ADL++VPGTR T+  LAWLR RGL  AL+   A G+P+LGICGGFQ+LG   R  D VE 
Sbjct: 300 ADLVIVPGTRGTVKALAWLRERGLADALLRRAAEGRPVLGICGGFQVLGE--RIEDDVES 357

Query: 353 PVAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARD 412
                +GLGLL V   FG EKVL  P G  LG    GYEIHHG +      + FL G R 
Sbjct: 358 RAGRVEGLGLLPVRVRFGREKVLARPVGTALGEPVEGYEIHHG-VAEVSGGEPFLDGCRV 416

Query: 413 GQVFGTMWHGSLEGDALREAFLRETLGLTG------SGTSFSAARERRLDLLGDLVERHL 466
           G V+GT WHGSLE DA R AFL E     G        TSF A RE +LD LGDL+E H 
Sbjct: 417 GSVWGTHWHGSLESDAFRRAFLTEVARAAGRRFAAAPDTSFGALREEQLDRLGDLIEEHA 476

Query: 467 DVDALLALARHG 478
           D DAL  L   G
Sbjct: 477 DTDALWRLIETG 488


>tr|A8LG25|A8LG25_FRASN Tax_Id=298653 SubName: Full=Cobyric acid
           synthase CobQ; Flags: Precursor;[Frankia sp.]
          Length = 508

 Score =  476 bits (1224), Expect = e-132
 Identities = 272/492 (55%), Positives = 316/492 (64%), Gaps = 23/492 (4%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGT SDAGKS LTAGLCR  AR GVRVAPFKAQNM+ NS+V       G EIGRAQ 
Sbjct: 10  LLVAGTASDAGKSVLTAGLCRWLAREGVRVAPFKAQNMALNSVVTAD----GAEIGRAQA 65

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA AA   PEAAMNPVLLKPGSD  S +V++GR   E+ +  +   ++ L         
Sbjct: 66  MQAAAAGVEPEAAMNPVLLKPGSDRHSQLVVLGRPVAEVDALGYRPHKERLLGIVLDCLA 125

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
           DL  R+D V+ EGAGSPAEINLRA D  NMGLA  A LP +VVGDIDRGGVFAA FGT+A
Sbjct: 126 DLRGRFDAVICEGAGSPAEINLRATDIANMGLARAANLPVLVVGDIDRGGVFAALFGTLA 185

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           LL   DQ  +AG+V+N+FRGD  LL PGLR LEG+TGR V G LPW   LWLD ED+LDL
Sbjct: 186 LLDRADQTHIAGWVINRFRGDARLLEPGLRQLEGLTGRPVLGVLPWLPGLWLDVEDSLDL 245

Query: 244 --------TGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDA 293
                    G  AA TG    RVAVVR PR+SN TD+DAL  EP + V  A+ P  + D 
Sbjct: 246 RSHPDPEADGSGAADTGPDRLRVAVVRFPRLSNITDLDALRAEPGVSVRLATTPDEIADV 305

Query: 294 DLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP 353
           DL+V+PGTRAT++DLAWLR RGL  AL A   AG P+LGICGG+QMLG  +R  D +E  
Sbjct: 306 DLVVLPGTRATVSDLAWLRRRGLAGALAARATAGLPILGICGGYQMLG--VRIEDEIESG 363

Query: 354 VAEADGLGLLDVETTFGAEKVLRLPRGQGL-GVTASGYEIHHGRITAGDAAQQF-LGGAR 411
             E  GLGLL + T F A+KVL    G    G   +GYEI HGR  A D+ + F + G R
Sbjct: 364 AGEVPGLGLLPLVTRFAADKVLGRRHGVSADGHPVTGYEIRHGRPAADDSLEPFAVDGVR 423

Query: 412 DGQVFGTMWHGSLEGDALREAFLRETLGLTGSG-----TSFSAARERRLDLLGDLVERHL 466
            G V+GT WHG LE D  R AFL       G       T F+  R RRLD LGDLV  HL
Sbjct: 424 RGGVYGTSWHGLLENDEFRRAFLTGVAATAGRSFRPAVTCFADVRARRLDALGDLVADHL 483

Query: 467 DVDALLALARHG 478
           D+  + AL   G
Sbjct: 484 DIATVRALLDRG 495


>sp|Q2J9S7|COBQ_FRASC Tax_Id=106370 (cobQ)RecName: Full=Cobyric acid
           synthase;[Frankia sp.]
          Length = 520

 Score =  474 bits (1220), Expect = e-131
 Identities = 275/510 (53%), Positives = 321/510 (62%), Gaps = 40/510 (7%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGT SDAGKS LTAG+CR  AR GVRVAPFKAQNM+ NS V       G EIGRAQ
Sbjct: 4   GLLVAGTASDAGKSVLTAGICRWLAREGVRVAPFKAQNMALNSAVTAD----GAEIGRAQ 59

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAF 122
            +QA AA   PEAAMNPVLLKPG    S +V++GR   E+ +  +   ++ LA       
Sbjct: 60  AMQAAAAGVEPEAAMNPVLLKPGGQRHSQLVVLGRPVAEVDALGYRPYKERLAAIVLECL 119

Query: 123 DDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTI 182
           DDL  R+D V+ EGAGSPAEINLR+ D  NMGLA  A LP IVVGDID+GGVFAA FGT+
Sbjct: 120 DDLRGRFDAVICEGAGSPAEINLRSTDIANMGLARAANLPVIVVGDIDKGGVFAALFGTL 179

Query: 183 ALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALD 242
           ALL A DQALVAG+V+N+FRGD  LL PGLR +E +TGR V G +PW A LWLD ED+LD
Sbjct: 180 ALLDAADQALVAGWVINRFRGDARLLEPGLRQIERLTGRPVHGVVPWKAGLWLDVEDSLD 239

Query: 243 LTG---------------------RRAASTGAH----RVAVVRLPRISNFTDVDALGLEP 277
           L                        R AS G      RVAV+RLPR+SN TD+DAL +EP
Sbjct: 240 LAAFPDAEPCPDAEPCPDAEPCPEARPASHGGRREVLRVAVIRLPRLSNVTDIDALRVEP 299

Query: 278 DLDVVFASDPRGLGDADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGF 337
            + V  A+ P  L DADL+++PGTR+T+ DL WLR RGL  AL    AA +P+LGICGG+
Sbjct: 300 GVAVRLATRPDELADADLVILPGTRSTVEDLRWLRRRGLAAALAERAAAARPVLGICGGY 359

Query: 338 QMLGRVIRDPDGVEGPVAEADGLGLLDVETTFGAEKVL-RLPRGQGLGVTASGYEIHHGR 396
           Q+LGR IR  D VE    E DGLGLL V TTF   K+L R       G   +GYEI HGR
Sbjct: 360 QILGRRIR--DDVESGAGEVDGLGLLPVITTFDPVKLLGRRAATDAAGRPLTGYEIRHGR 417

Query: 397 ITA---GDAAQQFLGGARDGQVFGTMWHGSLEGDALREAFLRETLGLTGSG-----TSFS 448
           +T     D+A     G R G V GT WHG LE DA R A+L +     G       T F+
Sbjct: 418 LTVEEHPDSAPFAADGVRVGAVAGTSWHGVLENDAFRRAYLADVATAAGRSFVPAFTCFA 477

Query: 449 AARERRLDLLGDLVERHLDVDALLALARHG 478
            AR+RRLD LGDLV  HLD  AL  L   G
Sbjct: 478 DARQRRLDALGDLVADHLDTGALRRLLAEG 507


>tr|C2ANV9|C2ANV9_TSUPA Tax_Id=521096 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Tsukamurella paurometabola DSM 20162]
          Length = 507

 Score =  473 bits (1216), Expect = e-131
 Identities = 255/483 (52%), Positives = 314/483 (65%), Gaps = 13/483 (2%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LL+AG TSDAGKST+TAGLCR  ARRGVRVAPFKAQNMSNNS+      G   EIGRAQ 
Sbjct: 5   LLIAGATSDAGKSTITAGLCRLLARRGVRVAPFKAQNMSNNSVATVETDGTSGEIGRAQA 64

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
            QALA    P    NPVLLKPGSD RS ++L GR  G++ + ++   RQ L +       
Sbjct: 65  TQALACGLAPSTRFNPVLLKPGSDRRSQLILHGRPVGDVGARDYITRRQWLLDEVTTTLQ 124

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L   +DVV+ EGAGSPAEINLRA D  NMGLA  A LPT+VVGDIDRGGV A   GT+A
Sbjct: 125 RLRDEFDVVLCEGAGSPAEINLRATDIANMGLARAAGLPTVVVGDIDRGGVLAHLAGTVA 184

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDAL-- 241
           +L  +DQ  +  F++N+FRGD+ LL PGL  LE +T R   G LP+  DLWLD+ED+L  
Sbjct: 185 VLDPDDQRHIYAFLINRFRGDVSLLTPGLEQLEDITRRPTVGVLPYLTDLWLDAEDSLAA 244

Query: 242 ---DLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVV 298
              DL G  +      RVA + LPR+SN TDV+AL  EP L V + + P  +  ADL+V+
Sbjct: 245 LGSDLVGPGSRRPDPLRVAAIALPRVSNTTDVEALACEPGLTVRWTTRPADVAAADLVVL 304

Query: 299 PGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPV-AEA 357
           PGT+AT+ADLAWLR RGL  AL+A  A G+P++G+CGG+QMLGR I DP G+E PV +  
Sbjct: 305 PGTKATVADLAWLRERGLADALVARAAGGRPIIGVCGGYQMLGRSIGDPHGIEAPVGSRV 364

Query: 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLG-----GARD 412
           DGLGLLD++  F A+K +R   G GLGV A+GYEIHHG +     +    G     GA  
Sbjct: 365 DGLGLLDLDIEFAADKCVRNVAGTGLGVRATGYEIHHGTVVRSTESHLLDGPDGAEGALA 424

Query: 413 GQVFGTMWHGSLEGDALREAFLRETL-GL-TGSGTSFSAARERRLDLLGDLVERHLDVDA 470
           G V GT WHG L  D  R A+L     G   G  TS+  AR  +LD + D +E H DVDA
Sbjct: 425 GPVLGTHWHGLLGSDEFRRAYLHRAFPGFDPGPVTSYDGARIAQLDRIADAIEEHCDVDA 484

Query: 471 LLA 473
           ++A
Sbjct: 485 IVA 487


>tr|Q0RLS3|Q0RLS3_FRAAA Tax_Id=326424 (bioD)SubName:
           Full=Dethiobiotin synthetase (Cobyric acid synthase);
           EC=6.3.3.3;[Frankia alni]
          Length = 531

 Score =  472 bits (1214), Expect = e-131
 Identities = 275/510 (53%), Positives = 323/510 (63%), Gaps = 40/510 (7%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGT SDAGKS LTAG+CR  AR GVRVAPFKAQNM+ NS V       G EIGRAQ
Sbjct: 15  GLLVAGTASDAGKSVLTAGICRWLAREGVRVAPFKAQNMALNSTVTAD----GAEIGRAQ 70

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAF 122
            +QA AA   PEAAMNPVLLKPG D  S ++++GR   E+ +  +   ++ LA+      
Sbjct: 71  AMQAAAAGVEPEAAMNPVLLKPGGDRHSQLIVLGRPVAEVDALGYRPHKERLAKIVLECL 130

Query: 123 DDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTI 182
           DDL  R+D V+ EGAGSPAEINLR+ D  NMGLA  A LP IVVGDID+GGVFAA FGT+
Sbjct: 131 DDLRGRFDAVICEGAGSPAEINLRSTDIANMGLARAANLPVIVVGDIDKGGVFAALFGTL 190

Query: 183 ALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALD 242
           ALL   DQALVAG+V+N+FRGD  LL PGLR +E +TGR V G +P+ + LWLD ED+LD
Sbjct: 191 ALLDRADQALVAGWVINRFRGDARLLEPGLRQIEALTGRPVHGVVPFRSGLWLDVEDSLD 250

Query: 243 LT-------------------GRRAASTG------AHRVAVVRLPRISNFTDVDALGLEP 277
           LT                       AS G      + RVAVVRLPR+SN TD+DAL  EP
Sbjct: 251 LTSYPDAEPDTDSGLAGEDASAGEGASAGDGVRRESLRVAVVRLPRLSNVTDLDALRAEP 310

Query: 278 DLDVVFASDPRGLGDADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGF 337
            + V   + P  L DADL+V+PGTR+T+ DL WLR RGL  A+ A VAAG+P+LGICGG+
Sbjct: 311 GVVVRLVTGPDELADADLVVLPGTRSTVEDLRWLRRRGLADAVAARVAAGRPVLGICGGY 370

Query: 338 QMLGRVIRDPDGVEGPVAEADGLGLLDVETTFGAEKVL-RLPRGQGLGVTASGYEIHHGR 396
           QMLGR I   D VE    E  GLGLL V TTF A K+L R       G   +GYEI HGR
Sbjct: 371 QMLGRRIH--DDVESGAGEVAGLGLLPVTTTFEASKLLGRRAATDAAGRPVTGYEIRHGR 428

Query: 397 ITAGD--AAQQFLG-GARDGQVFGTMWHGSLEGDALREAFLRETLGLTG-----SGTSFS 448
           +   D  AA+ F   G R G V GT WHG LE D  R A+L E     G     + T F+
Sbjct: 429 LAIADHPAAEPFAADGVRVGAVAGTSWHGLLENDEFRRAYLTEVARAAGRAFVPARTRFA 488

Query: 449 AARERRLDLLGDLVERHLDVDALLALARHG 478
             R RRLD+LGDLV  HLD  AL  L   G
Sbjct: 489 DVRRRRLDVLGDLVAEHLDTAALRRLLDEG 518


>tr|C9YZR0|C9YZR0_STRSW Tax_Id=680198 (cobQ)SubName: Full=Cobyric
           acid synthase;[Streptomyces scabies]
          Length = 508

 Score =  470 bits (1209), Expect = e-130
 Identities = 268/492 (54%), Positives = 313/492 (63%), Gaps = 23/492 (4%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGTTSDAGKS +TAG+CR   R+GV+VAPFKAQNMS NS V +     G EIGRAQ
Sbjct: 4   GLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTK----EGAEIGRAQ 59

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQV-LAETAHRA 121
            +QA A    P A MNPVLLKPG +  S VVL+GR  GE+++  +  GRQ  L  T    
Sbjct: 60  AMQAQACRVEPTALMNPVLLKPGGERSSQVVLLGRPVGEMSARGYHGGRQQRLLGTVLDC 119

Query: 122 FDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGT 181
             +L   YD V+ EGAGSPAEINLR  D VNMG+A +A LP +VVGDIDRGGVFA+FFGT
Sbjct: 120 LAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARNAGLPVLVVGDIDRGGVFASFFGT 179

Query: 182 IALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDAL 241
           +ALLS EDQALVAGF+VNKFRGD+ LL PGL  L G+TGR+ +G LP+   L +D ED L
Sbjct: 180 VALLSPEDQALVAGFLVNKFRGDVSLLEPGLDMLHGLTGRRTYGVLPFRHGLGIDEEDGL 239

Query: 242 --DLTGRRAASTGAH-------RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGD 292
              L G    S  A        RVAV  +P +SNFTDVDAL  EP + V F      L D
Sbjct: 240 RVSLRGTVRESNVAPPVGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRAEELAD 299

Query: 293 ADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEG 352
           ADL+VVPGTR T+  L WLR RGL  AL+   A G+P+LGICGGFQ+LG  I   D VE 
Sbjct: 300 ADLVVVPGTRGTVRALEWLRERGLAEALLRRAAEGRPVLGICGGFQLLGEHIE--DDVES 357

Query: 353 PVAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARD 412
                  LG+L V   F  +K L  P G+ LG    GYEIHHG +      + FL G R 
Sbjct: 358 RQGHVPALGVLPVRVRFAEDKTLTRPAGEALGERVEGYEIHHG-VAEVLGGEPFLDGCRV 416

Query: 413 GQVFGTMWHGSLEGDALREAFLRETLGLTG------SGTSFSAARERRLDLLGDLVERHL 466
           GQ +GT WHGSLE D  R AFLRE    +G        TSF+A RE +LD LGDL+E H 
Sbjct: 417 GQTWGTHWHGSLESDGFRRAFLREVAAASGRRFVPAPDTSFAALREEQLDRLGDLIEEHA 476

Query: 467 DVDALLALARHG 478
           D DAL  L   G
Sbjct: 477 DTDALWRLIESG 488


>tr|B1W1S6|B1W1S6_STRGG Tax_Id=455632 SubName: Full=Putative cobyric
           acid synthase;[Streptomyces griseus subsp. griseus]
          Length = 554

 Score =  469 bits (1206), Expect = e-130
 Identities = 267/492 (54%), Positives = 311/492 (63%), Gaps = 23/492 (4%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGTTSDAGKS +TAG+CR   RRGV+VAPFKAQNMS NS V +     G EIGRAQ
Sbjct: 4   GLLVAGTTSDAGKSVVTAGICRWLVRRGVKVAPFKAQNMSLNSFVTR----QGAEIGRAQ 59

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQ-VLAETAHRA 121
            +QA AA   P A MNPVLLKPGSD  S VVLMG+  GE+++  +  GRQ  L  T    
Sbjct: 60  AMQAQAARVEPTALMNPVLLKPGSDRSSQVVLMGKPVGEMSARGYHGGRQEALLGTVTEC 119

Query: 122 FDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGT 181
            + L + YD V+ EGAGSPAEINLR  D VNMG+A  A  P +VVGDIDRGGVFA+FFGT
Sbjct: 120 LEQLRSEYDAVICEGAGSPAEINLRRTDIVNMGIARAARFPVLVVGDIDRGGVFASFFGT 179

Query: 182 IALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDAL 241
            ALL  EDQ+LVAG++VNKFRGD+ LL PGL  L G+TGR+ +G LP+   L +D ED L
Sbjct: 180 TALLGPEDQSLVAGYLVNKFRGDVSLLEPGLDMLYGLTGRRTYGVLPYAHGLGIDEEDGL 239

Query: 242 DLTGRRAA---------STGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGD 292
            ++ R A               RVAV  +P +SNFTDVDAL  EP + V F      L D
Sbjct: 240 RVSLRGAVRESVVAPPHGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRAEELAD 299

Query: 293 ADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEG 352
           ADL++VPGTR T+  LAWLR RGL +AL+   A G+P+LGICGGFQ+LG  I D   VE 
Sbjct: 300 ADLVIVPGTRGTVKALAWLRERGLAQALVRRAAEGRPVLGICGGFQVLGERIEDE--VES 357

Query: 353 PVAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARD 412
                DGLG+L V   F  +K L  P G  LG    GYEIHHG +      + FL G R 
Sbjct: 358 RAGVVDGLGVLPVRIRFDRDKTLARPVGSALGEPVEGYEIHHG-VADVRGGEPFLDGCRV 416

Query: 413 GQVFGTMWHGSLEGDALREAFLRETLGLTG------SGTSFSAARERRLDLLGDLVERHL 466
           G V+GT WHGSLE DA R  FL E     G        TSF   RE +LD LGDLVE H 
Sbjct: 417 GAVWGTHWHGSLESDAFRRRFLVEVARAAGRRFVPAPDTSFGELREEQLDRLGDLVEEHA 476

Query: 467 DVDALLALARHG 478
           D DAL  L   G
Sbjct: 477 DTDALWRLIEGG 488


>sp|A4FM88|COBQ_SACEN Tax_Id=405948 (cobQ)RecName: Full=Cobyric acid
           synthase;[Saccharopolyspora erythraea]
          Length = 519

 Score =  468 bits (1205), Expect = e-130
 Identities = 269/500 (53%), Positives = 312/500 (62%), Gaps = 28/500 (5%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M  LL+AGTTSDAGKS + AG+CR  AR G RVAPFKAQNMSNNS+V    G    EIGR
Sbjct: 1   MNALLIAGTTSDAGKSVVAAGVCRWLARTGARVAPFKAQNMSNNSVVTPDGG----EIGR 56

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQ VQA A    P    NPVLLKPGSD RS VV++G   GE+ + ++ E +  L +T   
Sbjct: 57  AQAVQAAACGLEPSVRFNPVLLKPGSDRRSQVVVLGHVSGEVTAMSYRERKAALLDTVVS 116

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
             D L A +D V+ EGAGSPAEINLRA D  NMGLA  A LP +VVGDIDRGGVFA  FG
Sbjct: 117 TLDGLRAEHDHVICEGAGSPAEINLRATDIANMGLARAAGLPVLVVGDIDRGGVFAQLFG 176

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T+ALL A DQALV GFV+NKFRGD  LL  GL  L  +TGR V G LPW  DLWLD+ED+
Sbjct: 177 TLALLDAADQALVGGFVINKFRGDPALLDSGLDRLRALTGRPVHGVLPWAEDLWLDAEDS 236

Query: 241 LD-----LTGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDA 293
           L      + GR A   G+   RVAV RLPRISN TDV+AL  EP + V F ++P  L DA
Sbjct: 237 LSYVADGVVGRPAPPRGSQWLRVAVPRLPRISNATDVEALAAEPGVAVRFVTEPSRLTDA 296

Query: 294 DLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP 353
           DL+V+PG+++T+ADL WL   GL  A+ AH  AG P++GICGGFQML R  R  D VE  
Sbjct: 297 DLVVLPGSKSTVADLGWLHDTGLADAIRAHAGAGLPVVGICGGFQMLTR--RITDQVESG 354

Query: 354 VAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHG-RITAGDAAQQFL----- 407
           V   DGLG+LD+E  F   K LR P G   G    GYEIHHG  +  GD     +     
Sbjct: 355 VGAVDGLGMLDLEIEFEEAKTLRRPSGTAFGEPVDGYEIHHGVPVRRGDDLAGLVRLPGG 414

Query: 408 --GGARDGQVFGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLL 458
              G   G V GT WHG  E DA R  FL    G  G         TSF+  R  +LDLL
Sbjct: 415 TAEGGLSGSVAGTHWHGLFENDAFRRRFLTWAAGCAGRDGFVAAGDTSFAEVRAGQLDLL 474

Query: 459 GDLVERHLDVDALLALARHG 478
           GDLVE+HLD DA+  L   G
Sbjct: 475 GDLVEKHLDTDAIRRLLEGG 494


>tr|C6WER7|C6WER7_ACTMD Tax_Id=446462 SubName: Full=Cobyric acid
           synthase CobQ;[Actinosynnema mirum]
          Length = 509

 Score =  468 bits (1204), Expect = e-130
 Identities = 273/497 (54%), Positives = 315/497 (63%), Gaps = 31/497 (6%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           +LVAGTTSDAGKS L AGLCR  AR GVRVAPFKAQNMSNNS V    G    EIGRAQ 
Sbjct: 5   VLVAGTTSDAGKSVLVAGLCRWLAREGVRVAPFKAQNMSNNSAVTPDGG----EIGRAQA 60

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           VQA A    P    NPVLLKPG D  S VV++G+  GE+++ ++ E +  L         
Sbjct: 61  VQAAACGLEPSVRFNPVLLKPGGDRSSQVVVLGKVAGEVSAMSYRERKAELMTVVLDTLA 120

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L A ++ VV EGAGSPAEINLRA D  NMGLA  A LP +VVGDIDRGGV A  FGT+A
Sbjct: 121 GLRADHEAVVCEGAGSPAEINLRATDIANMGLARAAGLPVLVVGDIDRGGVLAHLFGTLA 180

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALD- 242
           LL   DQALVAGFVVNKFRGD  LL PGLR L  +TGR V G LPW  +LWLD+ED+L  
Sbjct: 181 LLDPADQALVAGFVVNKFRGDPALLEPGLRQLRELTGRPVHGVLPWREELWLDAEDSLSY 240

Query: 243 ----LTGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
               + GR  A  G    RVAVVRLPRISN TDV+AL  EP + V F ++P  L DADL+
Sbjct: 241 AADGVIGRPQAPVGRQWLRVAVVRLPRISNATDVEALACEPGVSVRFVTEPSRLADADLV 300

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PG++AT++DLAWLR  GL  A+ AH     P+LG+CGG+QML R I DP  VE     
Sbjct: 301 VLPGSKATVSDLAWLRRTGLADAIAAH---DGPVLGVCGGYQMLARSIDDP--VESGAGP 355

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRIT--AGDAAQQF------LG 408
             GLGLLDV+  F  EK L  P G  LG   +GYEIHHGR+   A D           + 
Sbjct: 356 VPGLGLLDVDVVFEPEKALHRPTGVALGEPVTGYEIHHGRVARRADDLPGLVELPGGEVE 415

Query: 409 GARDGQVFGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLLGDL 461
           GA  G+V GT WHG LE +  R AFLR   GL G         T F+A RE +LDLLGDL
Sbjct: 416 GAVRGRVVGTHWHGLLENNGFRRAFLRHVAGLAGRDGFEVAPDTDFAARREAQLDLLGDL 475

Query: 462 VERHLDVDALLALARHG 478
           V  HLD  A+ AL   G
Sbjct: 476 VVDHLDTGAVRALLERG 492


>sp|Q6AAP6|COBQ_PROAC Tax_Id=1747 (cobQ)RecName: Full=Cobyric acid
           synthase;[Propionibacterium acnes]
          Length = 484

 Score =  467 bits (1202), Expect = e-129
 Identities = 253/488 (51%), Positives = 317/488 (64%), Gaps = 16/488 (3%)

Query: 1   MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60
           M G+LVAGT+SDAGKS +   LCR   RRGV V PFKAQNMSNNSMVC      G EIGR
Sbjct: 1   MTGILVAGTSSDAGKSLVVTALCRVARRRGVDVVPFKAQNMSNNSMVCAD----GSEIGR 56

Query: 61  AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120
           AQ++QA AA  TP +AMNPVLLKPG+D RS VVL G+  G L +  +  GR+ LAE A  
Sbjct: 57  AQYLQATAAGVTPTSAMNPVLLKPGTDRRSFVVLRGKPGGVLEAGEYTTGRRYLAEAAWA 116

Query: 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180
           A+D+LAA +D+V+ EGAGSPAEINLR GDY NMGLA    LP ++VGDIDRGGV A+ FG
Sbjct: 117 AYDELAASHDMVICEGAGSPAEINLRRGDYTNMGLARAKNLPVVLVGDIDRGGVLASLFG 176

Query: 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240
           T ALL  +D+AL+AG++VNKFRGD  +LAPGL ++   TG   FG LPW   +WLD EDA
Sbjct: 177 TWALLDDDDRALLAGYIVNKFRGDDAILAPGLEEITDRTGMPSFGVLPWVPGVWLDGEDA 236

Query: 241 LDLTGRR----AASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
           L++   R    A    + RVAVVR PRISN TDVDA+  E  +DV   ++P     AD++
Sbjct: 237 LEVGRWRHEGDAVDPSSLRVAVVRFPRISNATDVDAMAGETGVDVQVTTNPDTCQAADVL 296

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVE-GPVA 355
           V+PG+R+T++DL WLR  G+   +      G+ ++GICGG+QML R I DPDG E  P +
Sbjct: 297 VLPGSRSTVSDLEWLRRSGIADVVARRAEQGRTVVGICGGYQMLCRTILDPDGQETTPGS 356

Query: 356 EADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQV 415
             +GLGLL VE  F A K L L  G   G+   GYEIHHG   + + A+ FL G   G V
Sbjct: 357 VVEGLGLLPVEVDFAATKTLALSHGTWRGIEVGGYEIHHGVCRSLEDAEAFLDGVHVGPV 416

Query: 416 FGTMWHGSLEGDALREAFLRETLGLTGSG-------TSFSAARERRLDLLGDLVERHLDV 468
           +GTMWHG+ E D  R  +L +     GS          + A RE  ++ L D +E H+DV
Sbjct: 417 WGTMWHGAFEHDEFRRTWLADAARHAGSSWRPHSDELGYQARREAMIETLADALEAHVDV 476

Query: 469 DALLALAR 476
           D +L L R
Sbjct: 477 DRILHLVR 484


>sp|Q9RJ20|COBQ_STRCO Tax_Id=1902 (cobQ)RecName: Full=Cobyric acid
           synthase;[Streptomyces coelicolor]
          Length = 502

 Score =  466 bits (1198), Expect = e-129
 Identities = 268/494 (54%), Positives = 313/494 (63%), Gaps = 27/494 (5%)

Query: 3   GLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQ 62
           GLLVAGTTSDAGKS +TAG+CR   R+GV+VAPFKAQNMS NS V +     G EIGRAQ
Sbjct: 4   GLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTRD----GAEIGRAQ 59

Query: 63  WVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQV-LAETAHRA 121
            +QA A    P A MNPVLLKPG +  S VVL+GR  GE+++  +  GRQ  L  T   +
Sbjct: 60  AMQAQACRVEPTAHMNPVLLKPGGERSSQVVLLGRPVGEMSARGYHGGRQERLLGTVLDS 119

Query: 122 FDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGT 181
             +L   YD V+ EGAGSPAEINLR  D VNMG+A  A LP +VVGDIDRGGVFA+FFGT
Sbjct: 120 LAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARGAGLPVLVVGDIDRGGVFASFFGT 179

Query: 182 IALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDAL 241
           +ALL+ EDQALVAGF+VNKFRGD+ LL PGL  L G+TGR+ +G LP+   L +D ED L
Sbjct: 180 VALLAPEDQALVAGFLVNKFRGDVSLLEPGLDMLHGLTGRRTYGVLPFRHGLGIDEEDGL 239

Query: 242 --DLTGRRAASTGAH-------RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGD 292
              L G    S  A        RVAV  +P +SNFTDVDAL  EP + V F   P  L D
Sbjct: 240 RVSLRGTVRESVVAPPVGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRPEELAD 299

Query: 293 ADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEG 352
           ADL++VPGTR T+  L WLR RGL  A+    A  +P+LGICGG+Q+LG  I D   VE 
Sbjct: 300 ADLVIVPGTRGTVRALEWLRERGLADAIARRAAERRPVLGICGGYQLLGEHIEDE--VES 357

Query: 353 PVAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHG--RITAGDAAQQFLGGA 410
                DGLGLL V   F  EK L    G+ LG    GYEIHHG   +T G     FL G 
Sbjct: 358 RAGHVDGLGLLPVRVRFDREKTLTRAVGEALGEPVEGYEIHHGVAEVTGG---APFLDGC 414

Query: 411 RDGQVFGTMWHGSLEGDALREAFLRETLGLTG------SGTSFSAARERRLDLLGDLVER 464
           R G+ +GT WHGSLE D  R AFLRE     G        TSF+A RE +LD LGDL+E 
Sbjct: 415 RVGRTWGTHWHGSLESDGFRRAFLREVAAAAGRRFVPAPDTSFAALREEQLDRLGDLIEH 474

Query: 465 HLDVDALLALARHG 478
           H D DAL  L   G
Sbjct: 475 HADTDALWRLIESG 488


>sp|Q5YSA4|COBQ_NOCFA Tax_Id=37329 (cobQ)RecName: Full=Cobyric acid
           synthase;[Nocardia farcinica]
          Length = 520

 Score =  461 bits (1186), Expect = e-127
 Identities = 267/509 (52%), Positives = 317/509 (62%), Gaps = 40/509 (7%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS + AGLCR  ARRGVRVAPFKAQNMSNNS+V    G    EIGRAQ 
Sbjct: 5   LLVAGTTSDAGKSVVVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGG----EIGRAQA 60

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA A    P    NPVLLKPGSD RS +V+ G++   + ++++F  R  L E       
Sbjct: 61  LQARACGLEPSVRFNPVLLKPGSDRRSQLVVRGQAVDTVGAADYFRHRTALREVVAAELA 120

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L A +DVV+ EGAGSPAEINLRA D  NMGLA  A+LP +VVGDIDRGGV A  FGT+A
Sbjct: 121 SLRAEFDVVLCEGAGSPAEINLRATDLANMGLARAADLPVLVVGDIDRGGVLAHLFGTVA 180

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           +L  +DQ L+AGFVVNKFRGD+DLL PGL  L  +TGR   G LP+  +LWLD+ED+L  
Sbjct: 181 VLEPDDQRLIAGFVVNKFRGDVDLLRPGLDRLAELTGRPTLGVLPFAEELWLDAEDSLGT 240

Query: 244 -----TGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
                 GR     G     VA VRLPRISN TDV+AL  EP + V + S+P  L DADL+
Sbjct: 241 VADAPVGRPRPPVGTEWLTVAAVRLPRISNSTDVEALACEPGVAVRWVSEPSRLADADLV 300

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           VVPG+++T++DLAWLR  GL  AL A V AG+P+L ICGG+QMLGR  R  D VE    E
Sbjct: 301 VVPGSKSTVSDLAWLRRTGLGEALRARVTAGRPVLAICGGYQMLGR--RIVDEVESGAGE 358

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAG---------DAAQQFL 407
             GLG+ D+ET F A KVLR   G G G    GYEIHHGR+            DA +  +
Sbjct: 359 VAGLGVFDLETEFAAPKVLRRVTGMGAGNPVRGYEIHHGRVRRSGDAPWLGLVDAPEAAV 418

Query: 408 GGARD-----------GQVFGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSA 449
            G  D           G  +GT  HG LE D  R A+LRE     G         TS +A
Sbjct: 419 DGGEDAVPLTPEGSVTGGAWGTHVHGLLESDGFRRAWLREVAARAGRHGFQVAPDTSVAA 478

Query: 450 ARERRLDLLGDLVERHLDVDALLALARHG 478
            R  +LDLL DLVE+HLD DAL  +   G
Sbjct: 479 VRAGQLDLLADLVEKHLDQDALERILTDG 507


>sp|C1B2W9|COBQ_RHOOB Tax_Id=632772 (cobQ)RecName: Full=Cobyric acid
           synthase;[Rhodococcus opacus]
          Length = 512

 Score =  458 bits (1179), Expect = e-127
 Identities = 266/495 (53%), Positives = 317/495 (64%), Gaps = 26/495 (5%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS L AGLCR  ARRGVRVAPFKAQNMSNNS+V    G    EIGRAQ 
Sbjct: 10  LLVAGTTSDAGKSVLVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGG----EIGRAQA 65

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA A    P    NPVLLKPGSD  S +V+ GR+   + + ++ E R  L         
Sbjct: 66  LQAAACGLEPSVRFNPVLLKPGSDRTSQLVVRGRAVTTVGARDYIEHRGHLRTVVAEELQ 125

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L A YDVV+ EGAGSPAEINLRA D  NMGLA  A+LP +VVGDIDRGGV A  FGT+A
Sbjct: 126 SLRADYDVVLCEGAGSPAEINLRATDLANMGLARAADLPVLVVGDIDRGGVLAHLFGTVA 185

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           +L+ EDQAL+AGFV+NKFRGD+ LLAPGL  L  +TGR   G +P+  DLWLD+ED+L +
Sbjct: 186 VLAPEDQALIAGFVINKFRGDVSLLAPGLGQLTAMTGRPTLGVIPFAEDLWLDAEDSLGV 245

Query: 244 -----TGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
                 GR A   G    RVA +RLPRISN TDV+AL  EP + V + +DP  L DADL+
Sbjct: 246 VGDAPVGRPAPPVGDDWLRVAAIRLPRISNSTDVEALACEPGVSVRWVTDPSRLEDADLV 305

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PG+++T++DL WLR  G+  A+  H   G P+LG+CGG+QMLG VI   D VE     
Sbjct: 306 VLPGSKSTVSDLEWLRRNGIADAIAVHAKRGGPVLGVCGGYQMLGSVI--VDDVESGRGA 363

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITA-GD-AAQQFLGGARDGQ 414
             GLGLLD+E  F  +KVL   RG   GV  SGYEIHHGR+   GD       GGA +G 
Sbjct: 364 VPGLGLLDLEVEFAPDKVLAQVRGDAHGVPVSGYEIHHGRVRRNGDPPLLHARGGAAEGS 423

Query: 415 ----VFGTMWHGSLEGDALREAFL---RETLGLTG----SGTSFSAARERRLDLLGDLVE 463
               V+GT WHG LE D  R   L    E  G TG      T  +A R  +LDLL DLVE
Sbjct: 424 IRGAVYGTHWHGLLETDRFRRILLDDVAEHAGRTGFVTAPDTDVAAIRTAQLDLLADLVE 483

Query: 464 RHLDVDALLALARHG 478
           ++LD+ AL AL   G
Sbjct: 484 QNLDLPALQALLGAG 498


>sp|Q0S258|COBQ_RHOSR Tax_Id=101510 (cobQ)RecName: Full=Cobyric acid
           synthase;[Rhodococcus sp.]
          Length = 512

 Score =  456 bits (1174), Expect = e-126
 Identities = 264/488 (54%), Positives = 312/488 (63%), Gaps = 26/488 (5%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS L AGLCR  ARRGVRVAPFKAQNMSNNS+V    G    EIGRAQ 
Sbjct: 10  LLVAGTTSDAGKSVLVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGG----EIGRAQA 65

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA A    P    NPVLLKPGSD  S +V+ GR+   + + ++ E RQ L         
Sbjct: 66  LQAAACGLEPSVRFNPVLLKPGSDRTSQLVVRGRAVTSVGARDYIEHRQHLRAVVAEELA 125

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L A YDVV+ EGAGSPAEINLRA D  NMGLA  A LP IVVGDIDRGGV A  FGT+A
Sbjct: 126 SLRADYDVVICEGAGSPAEINLRATDLANMGLARAAGLPVIVVGDIDRGGVLAHLFGTVA 185

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           +L  +DQAL+AGFV+NKFRGD+ LL PGL  L  VTGR   G +P+  DLWLD+ED+L +
Sbjct: 186 VLGPDDQALIAGFVINKFRGDVSLLGPGLEQLTAVTGRPTLGVIPFAEDLWLDAEDSLGV 245

Query: 244 -----TGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
                 GR A   G    RVA +RLPRISN TDV+AL  EP + V + +DP  L D DLI
Sbjct: 246 VGDAPVGRPAPPIGDDWLRVAAIRLPRISNSTDVEALACEPGVSVRWITDPSRLQDTDLI 305

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PG+++T++DL WLR  G+  A+ AH   G P+LG+CGG+QMLG VI   D VE     
Sbjct: 306 VLPGSKSTVSDLEWLRRNGIADAIAAHAKRGGPVLGVCGGYQMLGSVI--VDDVESGRGA 363

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITA-GD-----AAQQFLGGA 410
             GLGLLD+E  F  +KVL   RG   GV  SGYEIHHGR+   GD     A+     G+
Sbjct: 364 VPGLGLLDLEVEFAPDKVLAQVRGNAHGVPVSGYEIHHGRVRRNGDQPLLHASSGAAEGS 423

Query: 411 RDGQVFGTMWHGSLEGDALREAFL---RETLGLTG----SGTSFSAARERRLDLLGDLVE 463
             G V+GT WHG LE D  R   L    E  G TG      T  +A R  +LDLL DLVE
Sbjct: 424 IRGAVYGTHWHGLLETDRFRRLLLDDVAEHAGRTGFVTAPDTDVAAIRTAQLDLLADLVE 483

Query: 464 RHLDVDAL 471
           ++LD+ AL
Sbjct: 484 QNLDLRAL 491


>sp|Q1BAC5|COBQ_MYCSS Tax_Id=164756 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium sp.]
          Length = 495

 Score =  455 bits (1170), Expect = e-126
 Identities = 256/490 (52%), Positives = 312/490 (63%), Gaps = 27/490 (5%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS + AGLCR  AR+GVRVAPFKAQNMSNNS V    G    EIGRAQ 
Sbjct: 6   LLVAGTTSDAGKSMVVAGLCRLLARKGVRVAPFKAQNMSNNSAVTVDGG----EIGRAQA 61

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA AA   P    NPVLLKPGSD  S +V+ GR  G ++++++   R  LA+       
Sbjct: 62  MQARAAGLDPSVRFNPVLLKPGSDRTSQLVVRGRVTGTVSATDYITHRDRLADVVADELA 121

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L A +DVV+ EGAGSPAEINLR  D  NMGLA  A LP IVVGDIDRGGV A  FGT+A
Sbjct: 122 SLRAEFDVVLCEGAGSPAEINLRRTDLANMGLARRAHLPVIVVGDIDRGGVLAHLFGTVA 181

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           +L  +DQAL+AGFVVNKFRGD  LLAPGL  L  +TGR  +G +P+  +LW+D+ED++ +
Sbjct: 182 VLHPDDQALIAGFVVNKFRGDPTLLAPGLDQLHDLTGRPTYGVIPYSDELWMDTEDSVSV 241

Query: 244 T-----GRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
                 GR     GA   RVA VRLPRISN TD++AL  EP + V + +DP  + DAD++
Sbjct: 242 VAGRTIGRPTPPRGADGLRVAAVRLPRISNSTDIEALACEPGVTVRWVTDPADVADADVV 301

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PGT+AT+ADL WLR  GL   + AH  AG+PLLGICGGFQML R I   D VE     
Sbjct: 302 VLPGTKATVADLQWLRTAGLAEPIAAHAGAGRPLLGICGGFQMLCRHI--DDAVESRAGR 359

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLG-GARDGQV 415
            DGLGLLD +  F AEK LR            GYEIHHG++T   AA  + G G R   V
Sbjct: 360 VDGLGLLDADIAFAAEKTLR-----HRTTPLQGYEIHHGQVTR-CAADDWAGIGVRRDAV 413

Query: 416 FGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLLGDLVERHLDV 468
           +GT WHG  + D  R A+L +     G            SA R+ +LD++ DL++ HLD+
Sbjct: 414 YGTHWHGLFDNDGFRRAWLADAAAAAGRSGFVVADDIDVSARRDAQLDVMADLLQNHLDL 473

Query: 469 DALLALARHG 478
           DA L L   G
Sbjct: 474 DAALGLVDAG 483


>sp|A1UEN7|COBQ_MYCSK Tax_Id=189918 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium sp.]
          Length = 495

 Score =  455 bits (1170), Expect = e-126
 Identities = 256/490 (52%), Positives = 312/490 (63%), Gaps = 27/490 (5%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS + AGLCR  AR+GVRVAPFKAQNMSNNS V    G    EIGRAQ 
Sbjct: 6   LLVAGTTSDAGKSMVVAGLCRLLARKGVRVAPFKAQNMSNNSAVTVDGG----EIGRAQA 61

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA AA   P    NPVLLKPGSD  S +V+ GR  G ++++++   R  LA+       
Sbjct: 62  MQARAAGLDPSVRFNPVLLKPGSDRTSQLVVRGRVTGTVSATDYITHRDRLADVVADELA 121

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L A +DVV+ EGAGSPAEINLR  D  NMGLA  A LP IVVGDIDRGGV A  FGT+A
Sbjct: 122 SLRAEFDVVLCEGAGSPAEINLRRTDLANMGLARRAHLPVIVVGDIDRGGVLAHLFGTVA 181

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           +L  +DQAL+AGFVVNKFRGD  LLAPGL  L  +TGR  +G +P+  +LW+D+ED++ +
Sbjct: 182 VLHPDDQALIAGFVVNKFRGDPTLLAPGLDQLHDLTGRPTYGVIPYSDELWMDTEDSVSV 241

Query: 244 T-----GRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
                 GR     GA   RVA VRLPRISN TD++AL  EP + V + +DP  + DAD++
Sbjct: 242 VAGRTIGRPTPPRGADGLRVAAVRLPRISNSTDIEALACEPGVTVRWVTDPADVADADVV 301

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PGT+AT+ADL WLR  GL   + AH  AG+PLLGICGGFQML R I   D VE     
Sbjct: 302 VLPGTKATVADLQWLRTAGLAEPIAAHAGAGRPLLGICGGFQMLCRHI--DDAVESRAGR 359

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLG-GARDGQV 415
            DGLGLLD +  F AEK LR            GYEIHHG++T   AA  + G G R   V
Sbjct: 360 VDGLGLLDADIAFAAEKTLR-----HRTTPLQGYEIHHGQVTR-CAADDWAGIGVRRDAV 413

Query: 416 FGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLLGDLVERHLDV 468
           +GT WHG  + D  R A+L +     G            SA R+ +LD++ DL++ HLD+
Sbjct: 414 YGTHWHGLFDNDGFRRAWLADAAAAAGRSGFVVADDIDVSARRDAQLDVMADLLQNHLDL 473

Query: 469 DALLALARHG 478
           DA L L   G
Sbjct: 474 DAALGLVDAG 483


>sp|A3PY44|COBQ_MYCSJ Tax_Id=164757 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium sp.]
          Length = 495

 Score =  455 bits (1170), Expect = e-126
 Identities = 256/490 (52%), Positives = 312/490 (63%), Gaps = 27/490 (5%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS + AGLCR  AR+GVRVAPFKAQNMSNNS V    G    EIGRAQ 
Sbjct: 6   LLVAGTTSDAGKSMVVAGLCRLLARKGVRVAPFKAQNMSNNSAVTVDGG----EIGRAQA 61

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA AA   P    NPVLLKPGSD  S +V+ GR  G ++++++   R  LA+       
Sbjct: 62  MQARAAGLDPSVRFNPVLLKPGSDRTSQLVVRGRVTGTVSATDYITHRDRLADVVADELA 121

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L A +DVV+ EGAGSPAEINLR  D  NMGLA  A LP IVVGDIDRGGV A  FGT+A
Sbjct: 122 SLRAEFDVVLCEGAGSPAEINLRRTDLANMGLARRAHLPVIVVGDIDRGGVLAHLFGTVA 181

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           +L  +DQAL+AGFVVNKFRGD  LLAPGL  L  +TGR  +G +P+  +LW+D+ED++ +
Sbjct: 182 VLHPDDQALIAGFVVNKFRGDPTLLAPGLDQLHDLTGRPTYGVIPYSDELWMDTEDSVSV 241

Query: 244 T-----GRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
                 GR     GA   RVA VRLPRISN TD++AL  EP + V + +DP  + DAD++
Sbjct: 242 VAGRTIGRPTPPRGADGLRVAAVRLPRISNSTDIEALACEPGVTVRWVTDPADVADADVV 301

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PGT+AT+ADL WLR  GL   + AH  AG+PLLGICGGFQML R I   D VE     
Sbjct: 302 VLPGTKATVADLQWLRTAGLAEPIAAHAGAGRPLLGICGGFQMLCRHI--DDAVESRAGR 359

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLG-GARDGQV 415
            DGLGLLD +  F AEK LR            GYEIHHG++T   AA  + G G R   V
Sbjct: 360 VDGLGLLDADIAFAAEKTLR-----HRTTPLQGYEIHHGQVTR-CAADDWAGIGVRRDAV 413

Query: 416 FGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLLGDLVERHLDV 468
           +GT WHG  + D  R A+L +     G            SA R+ +LD++ DL++ HLD+
Sbjct: 414 YGTHWHGLFDNDGFRRAWLADAAAAAGRSGFVVADDIDVSARRDAQLDVMADLLQNHLDL 473

Query: 469 DALLALARHG 478
           DA L L   G
Sbjct: 474 DAALGLVDAG 483


>tr|C0ZY63|C0ZY63_RHOE4 Tax_Id=234621 (cobQ)SubName: Full=Cobyric
           acid synthase; EC=6.3.5.10;[Rhodococcus erythropolis]
          Length = 503

 Score =  452 bits (1163), Expect = e-125
 Identities = 255/491 (51%), Positives = 319/491 (64%), Gaps = 22/491 (4%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS L AGLCR  ARRGVRVAPFKAQNMSNNS+V    G    EIGRAQ 
Sbjct: 5   LLVAGTTSDAGKSVLVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGG----EIGRAQA 60

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA A    P    NPVLLKPGSD  S +V+ G++   + + ++ + RQ L        +
Sbjct: 61  LQARACGLEPSVRFNPVLLKPGSDRTSQLVVRGKAMTTVGARDYMQHRQWLRAVVAEDLE 120

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L + +DVV+ EGAGSPAEINLRA D  NMGLA  A++P +VVGDIDRGGV A  FGT+A
Sbjct: 121 SLRSEFDVVICEGAGSPAEINLRATDLANMGLAEAAQIPVVVVGDIDRGGVLAHLFGTVA 180

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           +LS  DQAL+AGFV+NKFRGD+ LL PGL  L  +TGR   G +P+  DLWLD+ED+L +
Sbjct: 181 VLSPSDQALIAGFVINKFRGDVALLEPGLDQLRSLTGRPTLGVIPFADDLWLDAEDSLGV 240

Query: 244 T-----GRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
           T     GR     G+    VA VRLPRISN TDV+AL  EP + V + +DP  + DADL+
Sbjct: 241 TGNAPVGRPGPPVGSAWLTVAAVRLPRISNSTDVEALACEPGVAVSWVTDPSRIRDADLV 300

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PG+++T++DL WLR+ GL   ++A V  G+ +LG+CGG+QMLG  I   D VE     
Sbjct: 301 VIPGSKSTVSDLEWLRSTGLADEIIARVGRGQAVLGVCGGYQMLGNSI--VDEVESGSGI 358

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRIT-AGDA-----AQQFLGGA 410
             GLGLLD++  F ++KVL    G   G++ SGYEIHHGR+   GD      +   L G+
Sbjct: 359 TAGLGLLDLDIEFASDKVLAQVTGSADGISVSGYEIHHGRVVHNGDRPLLADSGGVLEGS 418

Query: 411 RDGQVFGTMWHGSLEGDALREAFLRETL---GLTGSGTSFSAARERRLDLLGDLVERHLD 467
             G V GT WHG LE D  R + LRE      +    TS +A RE++LDLL DLVE+HLD
Sbjct: 419 VRGSVRGTHWHGLLESDDFRRSLLREIAVPGFVAAPDTSVAAVREQQLDLLADLVEQHLD 478

Query: 468 VDALLALARHG 478
            D L  L   G
Sbjct: 479 QDLLEKLINGG 489


>tr|C3JM17|C3JM17_RHOER Tax_Id=596309 (cobQ)SubName: Full=Cobyric
           acid synthase CobQ; EC=6.3.5.10;[Rhodococcus
           erythropolis SK121]
          Length = 503

 Score =  449 bits (1156), Expect = e-124
 Identities = 255/493 (51%), Positives = 317/493 (64%), Gaps = 26/493 (5%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS L AGLCR  ARRGVRVAPFKAQNMSNNS+V    G    EIGRAQ 
Sbjct: 5   LLVAGTTSDAGKSVLVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGG----EIGRAQA 60

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA A    P    NPVLLKPGSD  S +V+ G++   + + ++ + RQ L        +
Sbjct: 61  LQARACGLEPSVRFNPVLLKPGSDRTSQLVVRGKAMTTVGARDYMQHRQWLRAVVAEDLE 120

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L + +DVV+ EGAGSPAEINLRA D  NMGLA  A +P +VVGDIDRGGV A  FGT+A
Sbjct: 121 SLRSEFDVVICEGAGSPAEINLRATDLANMGLAEAARIPVVVVGDIDRGGVLAHLFGTVA 180

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           +LS  DQAL+AGFV+NKFRGD+ LL PGL  L  +TGR   G +P+  DLWLD+ED+L +
Sbjct: 181 VLSPSDQALIAGFVINKFRGDVALLEPGLEQLRSLTGRPTLGVIPFADDLWLDAEDSLGV 240

Query: 244 T-----GRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
           T     GR     G+    VA VRLPRISN TDV+AL  EP + V + +DP  + DADL+
Sbjct: 241 TGNAPVGRPGPPVGSAWLTVAAVRLPRISNSTDVEALACEPGVAVSWVTDPSRIRDADLV 300

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PG+++T++DL WLR+ GL   ++A    G+ +LGICGG+QMLG  I   D VE     
Sbjct: 301 VIPGSKSTVSDLEWLRSTGLADEIVARAGRGQAVLGICGGYQMLGNSI--VDDVESGSGT 358

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRIT-------AGDAAQQFLGG 409
             GLGLLD++  F  +KVL    G   G++ SGYEIHHGR+          D++    G 
Sbjct: 359 TAGLGLLDLDVEFAPDKVLAQMTGTADGISVSGYEIHHGRVVRNGDHPLLADSSGMPEGS 418

Query: 410 ARDGQVFGTMWHGSLEGDALREAFLRETLGLTG----SGTSFSAARERRLDLLGDLVERH 465
            R G V GT WHG LE D  R + LRE L + G      T+ +A RE++LDLL DLVE+H
Sbjct: 419 VR-GPVRGTHWHGLLESDDFRRSLLRE-LAVPGFVAAPDTAVAAVREQQLDLLADLVEQH 476

Query: 466 LDVDALLALARHG 478
           LD D L  L   G
Sbjct: 477 LDQDLLEKLINGG 489


>tr|Q1AYC4|Q1AYC4_RUBXD Tax_Id=266117 SubName: Full=Adenosylcobyric
           acid synthase (Glutamine-hydrolysing);
           EC=6.3.5.10;[Rubrobacter xylanophilus]
          Length = 499

 Score =  444 bits (1143), Expect = e-123
 Identities = 262/487 (53%), Positives = 308/487 (63%), Gaps = 22/487 (4%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLV GT SDAGKS + AG+CR  AR GVRVAPFKAQNM+ NS V +     G EIGRAQ 
Sbjct: 5   LLVCGTHSDAGKSVVVAGICRWLAREGVRVAPFKAQNMALNSFVTR----EGAEIGRAQA 60

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
            QA AA   PEAAMNPVLLKP +  R+ VV++GR +   +++++ + +  L      A +
Sbjct: 61  AQAAAARVEPEAAMNPVLLKPSAGERTQVVVLGRPYATASAASYQDMKPELLPVVLGALE 120

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L  R++ VV EGAGSPAEINLR  D  NMGLA  A LP ++VGDIDRGG+FA+ +GT+A
Sbjct: 121 GLRRRFEAVVCEGAGSPAEINLRESDLANMGLAQAAGLPVVLVGDIDRGGLFASLYGTLA 180

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           LLS  D+ LV GFVVNKFRGD  +LAPGL +L   TGR   GTLP+   + LD ED+L L
Sbjct: 181 LLSPRDRELVRGFVVNKFRGDAAILAPGLAELSRRTGRPFLGTLPFAPGIGLDGEDSLAL 240

Query: 244 --TGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPGT 301
              G  A      RVAVVRL R+SNFTD+D L  EP + V F      + DADL VVPGT
Sbjct: 241 REAGEGAPGGDVLRVAVVRLGRMSNFTDLDPLLFEPGVAVRFTRSAAEVLDADLAVVPGT 300

Query: 302 RATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGLG 361
           +AT+ DL  LRA GLDRAL A    G P LG+CGG+QMLGR  R  DGVEG V EA+GLG
Sbjct: 301 KATVEDLGGLRAAGLDRALAARARRGLPTLGLCGGYQMLGR--RIVDGVEGEVPEAEGLG 358

Query: 362 LLDVETTFGAEKVLRLPRGQGL---GVTASGYEIHHGRITAGDAAQQFL------GGARD 412
           LL VET F  EKVL  P G+         SGYEIHHGR         F+       G R 
Sbjct: 359 LLPVETVFEPEKVLARPSGRAPLFGDEEVSGYEIHHGRTARLGGEPLFVTREGGGEGCRV 418

Query: 413 GQVFGTMWHGSLEGDALREAFLRETLGLTGSG-----TSFSAARERRLDLLGDLVERHLD 467
           G V GT WHG LE D  R A L    G+ G G      SF+A RE RL+ LGDLV  HLD
Sbjct: 419 GAVLGTSWHGVLECDGFRRALLGWVAGVRGLGWEPGDFSFAALREERLERLGDLVAEHLD 478

Query: 468 VDALLAL 474
            DALL +
Sbjct: 479 RDALLGI 485


>sp|A0QVI7|COBQ_MYCS2 Tax_Id=246196 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium smegmatis]
          Length = 496

 Score =  440 bits (1132), Expect = e-121
 Identities = 250/490 (51%), Positives = 305/490 (62%), Gaps = 27/490 (5%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGTTSDAGKS L  GLCR   R+G+ VAPFKAQNMSNNS V    G    EIGRAQ 
Sbjct: 6   LLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGG----EIGRAQA 61

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA AA   P    NP+LLKPG D  S +V+ G+  G +A++++   R  LA        
Sbjct: 62  MQARAAGLAPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELS 121

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L   +D V+ EGAGSPAEINLRA D  NMGLA  A LP IVVGDIDRGG+ A   GT+A
Sbjct: 122 SLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVA 181

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALD- 242
           +L   DQALV+GFVVNKFRGD  LLAPGLR L  +TGR  +G +P+H ++WLD+ED++  
Sbjct: 182 VLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSV 241

Query: 243 ----LTGRRAASTGAH--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
               L G      G     VA +RLPRISN TD++AL  EP + V + +D   L  ADL+
Sbjct: 242 RPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLV 301

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PG++AT+ DL WLR RGL   + AH AAG+ +LG+CGGFQML   I DP  VE     
Sbjct: 302 VIPGSKATVTDLRWLRERGLAAGIAAHAAAGRAVLGVCGGFQMLCSRIDDP--VESREGR 359

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLG-GARDGQV 415
            DGLGLLD +  F A+K LR            GYEIHHG++ A  A   +LG G R G V
Sbjct: 360 VDGLGLLDADIEFAAQKTLR-----HWETPLHGYEIHHGQV-ARSAETDWLGIGLRRGAV 413

Query: 416 FGTMWHGSLEGDALREAFLRETLGLTG-------SGTSFSAARERRLDLLGDLVERHLDV 468
           +GT WHG L+ DALR  +L E     G            SA R+ +LDL+ DL+E HLDV
Sbjct: 414 YGTHWHGLLDNDALRRDWLTEVAAAAGRDGFVVADDVDVSARRDAQLDLMADLIENHLDV 473

Query: 469 DALLALARHG 478
            A+L L  HG
Sbjct: 474 GAILDLLEHG 483


>sp|Q73VS8|COBQ_MYCPA Tax_Id=1770 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium paratuberculosis]
          Length = 497

 Score =  438 bits (1126), Expect = e-121
 Identities = 255/491 (51%), Positives = 308/491 (62%), Gaps = 34/491 (6%)

Query: 4   LLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQW 63
           LLVAGT+SDAGKS + AGLCR  ARRGVRVAPFKAQNMSNNS V    G    EIGRAQ 
Sbjct: 5   LLVAGTSSDAGKSVVVAGLCRLLARRGVRVAPFKAQNMSNNSAVTVEGG----EIGRAQA 60

Query: 64  VQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFD 123
           +QA AA   P    NP+LLKPGSD  S +V+ G+    + ++++ + R  LA        
Sbjct: 61  IQARAAGLEPSVRFNPILLKPGSDRTSQLVIKGQVAESVTATSYVQHRDRLAALVLNELT 120

Query: 124 DLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIA 183
            L   +D V+ EGAGSPAEINLRA D  NMGLA  A+L  I+VGDIDRGG+ A  FGT+A
Sbjct: 121 CLRDEFDAVICEGAGSPAEINLRATDLANMGLARAADLAVILVGDIDRGGLLAHLFGTVA 180

Query: 184 LLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDL 243
           +L  +DQAL+AGFVVNKFRGD  LL PGLR L  +TGR  +G LP+   LWLD+ED+L +
Sbjct: 181 VLDPQDQALIAGFVVNKFRGDPALLQPGLRRLHDITGRPTYGVLPYADRLWLDAEDSLSV 240

Query: 244 TGRRAASTGAH-------RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLI 296
              R              RVA VRLPRISN TDV+AL  EP + V + S+P  + DADL+
Sbjct: 241 LAHRVVGAPDPPLGDDWLRVAAVRLPRISNSTDVEALACEPGVLVRWVSEPSDVADADLV 300

Query: 297 VVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAE 356
           V+PG++AT+ADL+WLR RGL  A+ AH AAG+P+LGICGGFQML R  R  D VE    E
Sbjct: 301 VIPGSKATVADLSWLRERGLAAAITAHAAAGRPVLGICGGFQMLCR--RIDDRVESGAGE 358

Query: 357 ADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITA--------GDAAQQFLG 408
             GLGLLD +  F   K LR  R Q      +GYEIHHGR++          DA  Q   
Sbjct: 359 VAGLGLLDADIAFHPAKTLR--RWQR---PLAGYEIHHGRVSRCAEHSWFDSDAEPQ--- 410

Query: 409 GARDGQVFGTMWHGSLEGDALREAFLRETLGLTG-----SGTSFSAARERRLDLLGDLVE 463
           G   G VFGT WHG L+ D  R A+L       G       T  +A R+ +LDL  DL+ 
Sbjct: 411 GLVRGAVFGTHWHGLLDNDDFRRAWLVRVADAAGRRFVPGDTDVAARRDAQLDLAADLLA 470

Query: 464 RHLDVDALLAL 474
            HLDVDA+L L
Sbjct: 471 AHLDVDAVLGL 481


  Database: Amellifera_nr
    Posted date:  Feb 5, 2010  5:10 AM
  Number of letters in database: 3,846,993,858
  Number of sequences in database:  11,275,203
  
Lambda     K      H
   0.321    0.138    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11275203
Number of Hits to DB: 3,758,598,320
Number of extensions: 168295117
Number of successful extensions: 420104
Number of sequences better than 10.0: 3128
Number of HSP's gapped: 418823
Number of HSP's successfully gapped: 3246
Length of query: 491
Length of database: 3,846,993,858
Length adjustment: 142
Effective length of query: 349
Effective length of database: 2,245,915,032
Effective search space: 783824346168
Effective search space used: 783824346168
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 82 (36.2 bits)