BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MMAR_4355
         (332 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,275,203 sequences; 3,846,993,858 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|B2HT41|B2HT41_MYCMM Tax_Id=216594 (ispH)SubName: Full=4-hydro...   592   e-167
sp|A0PKQ3|ISPH_MYCUA Tax_Id=362242 (ispH)RecName: Full=4-hydroxy...   585   e-165
sp|Q73WH6|ISPH_MYCPA Tax_Id=1770 (ispH)RecName: Full=4-hydroxy-3...   531   e-149
sp|P0A5I0|ISPH1_MYCTU Tax_Id=1773 (ispH1)RecName: Full=4-hydroxy...   530   e-149
sp|P0A5I1|ISPH1_MYCBO Tax_Id=1765 (ispH1)RecName: Full=4-hydroxy...   530   e-149
tr|C6DV51|C6DV51_MYCTK Tax_Id=478434 SubName: Full=LytB-related ...   530   e-149
tr|C1AMA4|C1AMA4_MYCBT Tax_Id=561275 (lytB)SubName: Full=4-hydro...   530   e-149
tr|A5U1F7|A5U1F7_MYCTA Tax_Id=419947 (lytB2)SubName: Full=4-hydr...   530   e-149
tr|A1KHQ0|A1KHQ0_MYCBP Tax_Id=410289 (lytB2)SubName: Full=Probab...   530   e-149
tr|A5WLD6|A5WLD6_MYCTF Tax_Id=336982 SubName: Full=LytB-related ...   530   e-149
tr|A4KG41|A4KG41_MYCTU Tax_Id=395095 SubName: Full=LytB-related ...   530   e-149
tr|A2VH26|A2VH26_MYCTU Tax_Id=348776 SubName: Full=LytB-related ...   530   e-149
sp|Q1B4H4|ISPH_MYCSS Tax_Id=164756 (ispH)RecName: Full=4-hydroxy...   499   e-139
sp|A1UKL5|ISPH_MYCSK Tax_Id=189918 (ispH)RecName: Full=4-hydroxy...   499   e-139
sp|A3Q4N0|ISPH_MYCSJ Tax_Id=164757 (ispH)RecName: Full=4-hydroxy...   499   e-139
sp|A4T986|ISPH_MYCGI Tax_Id=350054 (ispH)RecName: Full=4-hydroxy...   496   e-138
sp|A1TE06|ISPH_MYCVP Tax_Id=350058 (ispH)RecName: Full=4-hydroxy...   495   e-138
sp|Q9X781|ISPH_MYCLE Tax_Id=1769 (ispH)RecName: Full=4-hydroxy-3...   495   e-138
tr|B8ZSG0|B8ZSG0_MYCLB Tax_Id=561304 (lytB2)SubName: Full=LytB h...   495   e-138
tr|A0R2T2|A0R2T2_MYCS2 Tax_Id=246196 (ispH)SubName: Full=4-hydro...   481   e-134
tr|B1MKQ3|B1MKQ3_MYCA9 Tax_Id=561007 SubName: Full=Probable 4-hy...   479   e-133
tr|A0QC38|A0QC38_MYCA1 Tax_Id=243243 (ispH)SubName: Full=4-hydro...   471   e-131
sp|C1A2V7|ISPH_RHOE4 Tax_Id=234621 (ispH)RecName: Full=4-hydroxy...   454   e-126
tr|C3JU01|C3JU01_RHOER Tax_Id=596309 (ispH)SubName: Full=4-hydro...   454   e-126
sp|Q5YQ94|ISPH_NOCFA Tax_Id=37329 (ispH)RecName: Full=4-hydroxy-...   453   e-125
sp|C1AYI4|ISPH_RHOOB Tax_Id=632772 (ispH)RecName: Full=4-hydroxy...   452   e-125
sp|Q0S489|ISPH_RHOSR Tax_Id=101510 (ispH)RecName: Full=4-hydroxy...   451   e-125
tr|D0L7T7|D0L7T7_GORB4 Tax_Id=526226 SubName: Full=Hydroxymethyl...   438   e-121
tr|C2AV51|C2AV51_TSUPA Tax_Id=521096 SubName: Full=4-hydroxy-3-m...   438   e-121
tr|C7MYN2|C7MYN2_SACVD Tax_Id=471857 SubName: Full=4-hydroxy-3-m...   407   e-112
tr|C6WKT7|C6WKT7_ACTMD Tax_Id=446462 SubName: Full=Hydroxymethyl...   407   e-111
tr|A3TGX7|A3TGX7_9MICO Tax_Id=313589 SubName: Full=4-hydroxy-3-m...   403   e-110
tr|C1WEF1|C1WEF1_9ACTO Tax_Id=479435 SubName: Full=4-hydroxy-3-m...   399   e-109
tr|D1BKR9|D1BKR9_9MICO Tax_Id=446469 SubName: Full=4-hydroxy-3-m...   398   e-109
tr|C7R1U2|C7R1U2_JONDD Tax_Id=471856 SubName: Full=Hydroxymethyl...   398   e-109
tr|C0U3C2|C0U3C2_9ACTO Tax_Id=526225 SubName: Full=4-hydroxy-3-m...   397   e-109
tr|A4F898|A4F898_SACEN Tax_Id=405948 SubName: Full=4-hydroxy-3-m...   393   e-107
tr|C5C0V8|C5C0V8_BEUC1 Tax_Id=471853 SubName: Full=Hydroxymethyl...   392   e-107
tr|C9ND23|C9ND23_9ACTO Tax_Id=591167 SubName: Full=Hydroxymethyl...   390   e-106
tr|C0XPW6|C0XPW6_9CORY Tax_Id=525263 (ispH)SubName: Full=4-hydro...   390   e-106
tr|C0E7L6|C0E7L6_9CORY Tax_Id=566549 SubName: Full=Putative unch...   389   e-106
sp|B1W2D7|ISPH_STRGG Tax_Id=455632 (ispH)RecName: Full=4-hydroxy...   388   e-106
tr|C5VBB7|C5VBB7_9CORY Tax_Id=553207 (ispH)SubName: Full=4-hydro...   388   e-106
tr|C1RMZ8|C1RMZ8_9CELL Tax_Id=446466 SubName: Full=4-hydroxy-3-m...   387   e-106
tr|D1A8I1|D1A8I1_THECU Tax_Id=471852 SubName: Full=Hydroxymethyl...   387   e-105
tr|D0WPZ0|D0WPZ0_9ACTO Tax_Id=649743 SubName: Full=4-hydroxy-3-m...   386   e-105
tr|C4RPS1|C4RPS1_9ACTO Tax_Id=219305 SubName: Full=Hydroxymethyl...   385   e-105
tr|C7NKU3|C7NKU3_KYTSD Tax_Id=478801 SubName: Full=4-hydroxy-3-m...   384   e-105
tr|A0JYU2|A0JYU2_ARTS2 Tax_Id=290399 SubName: Full=4-hydroxy-3-m...   384   e-105
tr|C4DTW7|C4DTW7_9ACTO Tax_Id=446470 SubName: Full=4-hydroxy-3-m...   383   e-104

>tr|B2HT41|B2HT41_MYCMM Tax_Id=216594 (ispH)SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
           IspH;[Mycobacterium marinum]
          Length = 332

 Score =  592 bits (1527), Expect = e-167
 Identities = 303/332 (91%), Positives = 303/332 (91%)

Query: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60
           MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE
Sbjct: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60

Query: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120
           IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL
Sbjct: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120

Query: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180
           VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV
Sbjct: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180

Query: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXX 240
           VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECD      
Sbjct: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDLVLVVG 240

Query: 241 XXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLE 300
                        ALGAGAQAAYLVDWADDIDQSWLQ          ASVPEVLVRGVLE
Sbjct: 241 SRNSSNSVRLVEVALGAGAQAAYLVDWADDIDQSWLQGVTTVGVTSGASVPEVLVRGVLE 300

Query: 301 RLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           RLAESGYDMVQPVTTANETLVFALPREIRPAR
Sbjct: 301 RLAESGYDMVQPVTTANETLVFALPREIRPAR 332


>sp|A0PKQ3|ISPH_MYCUA Tax_Id=362242 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium ulcerans]
          Length = 332

 Score =  585 bits (1509), Expect = e-165
 Identities = 299/332 (90%), Positives = 301/332 (90%)

Query: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60
           MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE
Sbjct: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60

Query: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120
           IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL
Sbjct: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120

Query: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180
           VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDG ERVTIRDE+KV
Sbjct: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGVERVTIRDEDKV 180

Query: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXX 240
           VWLSQTTLSVDETMEIVARLRQRF KLQDPPSDDICYATQNRQVAVKAMAPECD      
Sbjct: 181 VWLSQTTLSVDETMEIVARLRQRFAKLQDPPSDDICYATQNRQVAVKAMAPECDLVLVVG 240

Query: 241 XXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLE 300
                        ALGAGA+AAYLVDWADDIDQSWLQ          ASVPEVLVRGVLE
Sbjct: 241 SRNSSNSVRLVEVALGAGAEAAYLVDWADDIDQSWLQGVTTVGVTSGASVPEVLVRGVLE 300

Query: 301 RLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           RLAESGYDMVQPVTTANETLVFALPREIRPAR
Sbjct: 301 RLAESGYDMVQPVTTANETLVFALPREIRPAR 332


>sp|Q73WH6|ISPH_MYCPA Tax_Id=1770 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium paratuberculosis]
          Length = 332

 Score =  531 bits (1369), Expect = e-149
 Identities = 270/332 (81%), Positives = 285/332 (85%)

Query: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60
           M PT+DMGIPGASSSVA  PTR+RVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE
Sbjct: 1   MPPTVDMGIPGASSSVAVNPTRKRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60

Query: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120
           IVHNRHVV TL KAGAVFVEETD+VPEGAIVVFSAHGVAPTV+AAAAERNL TIDATCPL
Sbjct: 61  IVHNRHVVSTLEKAGAVFVEETDEVPEGAIVVFSAHGVAPTVHAAAAERNLHTIDATCPL 120

Query: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180
           VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+   + V +RDE+KV
Sbjct: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVAAVDNVRVRDEDKV 180

Query: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXX 240
           VWLSQTTLSVDETMEIV RLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECD      
Sbjct: 181 VWLSQTTLSVDETMEIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVG 240

Query: 241 XXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLE 300
                        ALG GA AA+LVDWADDID +WL+          ASVPEVLV+GVLE
Sbjct: 241 SRNSSNSVRLVEVALGGGAGAAHLVDWADDIDPAWLEGVTTVGVTSGASVPEVLVQGVLE 300

Query: 301 RLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           RLAE G+D+VQPVTTA ETLVFALPREIR AR
Sbjct: 301 RLAECGFDVVQPVTTAQETLVFALPREIRSAR 332


>sp|P0A5I0|ISPH1_MYCTU Tax_Id=1773 (ispH1)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
           1; EC=1.17.1.2;[Mycobacterium tuberculosis]
          Length = 335

 Score =  530 bits (1366), Expect = e-149
 Identities = 268/335 (80%), Positives = 289/335 (86%), Gaps = 3/335 (0%)

Query: 1   MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
           MVPT+DMGIPGAS    SVA  P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct: 1   MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60

Query: 58  RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
           RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct: 61  RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120

Query: 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
           CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D  ++VT+RDE
Sbjct: 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180

Query: 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXX 237
           +KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+   
Sbjct: 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240

Query: 238 XXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRG 297
                           ALGAGA+AA+LVDWADDID +WL           ASVPEVLVRG
Sbjct: 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300

Query: 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           VLERLAE GYD+VQPVTTANETLVFALPRE+R  R
Sbjct: 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335


>sp|P0A5I1|ISPH1_MYCBO Tax_Id=1765 (ispH1)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
           1; EC=1.17.1.2;[Mycobacterium bovis]
          Length = 335

 Score =  530 bits (1366), Expect = e-149
 Identities = 268/335 (80%), Positives = 289/335 (86%), Gaps = 3/335 (0%)

Query: 1   MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
           MVPT+DMGIPGAS    SVA  P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct: 1   MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60

Query: 58  RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
           RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct: 61  RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120

Query: 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
           CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D  ++VT+RDE
Sbjct: 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180

Query: 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXX 237
           +KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+   
Sbjct: 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240

Query: 238 XXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRG 297
                           ALGAGA+AA+LVDWADDID +WL           ASVPEVLVRG
Sbjct: 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300

Query: 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           VLERLAE GYD+VQPVTTANETLVFALPRE+R  R
Sbjct: 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335


>tr|C6DV51|C6DV51_MYCTK Tax_Id=478434 SubName: Full=LytB-related
           protein lytB2;[Mycobacterium tuberculosis]
          Length = 335

 Score =  530 bits (1366), Expect = e-149
 Identities = 268/335 (80%), Positives = 289/335 (86%), Gaps = 3/335 (0%)

Query: 1   MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
           MVPT+DMGIPGAS    SVA  P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct: 1   MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60

Query: 58  RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
           RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct: 61  RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120

Query: 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
           CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D  ++VT+RDE
Sbjct: 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180

Query: 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXX 237
           +KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+   
Sbjct: 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240

Query: 238 XXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRG 297
                           ALGAGA+AA+LVDWADDID +WL           ASVPEVLVRG
Sbjct: 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300

Query: 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           VLERLAE GYD+VQPVTTANETLVFALPRE+R  R
Sbjct: 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335


>tr|C1AMA4|C1AMA4_MYCBT Tax_Id=561275 (lytB)SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium bovis]
          Length = 335

 Score =  530 bits (1366), Expect = e-149
 Identities = 268/335 (80%), Positives = 289/335 (86%), Gaps = 3/335 (0%)

Query: 1   MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
           MVPT+DMGIPGAS    SVA  P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct: 1   MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60

Query: 58  RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
           RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct: 61  RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120

Query: 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
           CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D  ++VT+RDE
Sbjct: 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180

Query: 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXX 237
           +KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+   
Sbjct: 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240

Query: 238 XXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRG 297
                           ALGAGA+AA+LVDWADDID +WL           ASVPEVLVRG
Sbjct: 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300

Query: 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           VLERLAE GYD+VQPVTTANETLVFALPRE+R  R
Sbjct: 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335


>tr|A5U1F7|A5U1F7_MYCTA Tax_Id=419947 (lytB2)SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate
           reductase;[Mycobacterium tuberculosis]
          Length = 335

 Score =  530 bits (1366), Expect = e-149
 Identities = 268/335 (80%), Positives = 289/335 (86%), Gaps = 3/335 (0%)

Query: 1   MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
           MVPT+DMGIPGAS    SVA  P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct: 1   MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60

Query: 58  RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
           RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct: 61  RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120

Query: 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
           CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D  ++VT+RDE
Sbjct: 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180

Query: 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXX 237
           +KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+   
Sbjct: 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240

Query: 238 XXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRG 297
                           ALGAGA+AA+LVDWADDID +WL           ASVPEVLVRG
Sbjct: 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300

Query: 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           VLERLAE GYD+VQPVTTANETLVFALPRE+R  R
Sbjct: 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335


>tr|A1KHQ0|A1KHQ0_MYCBP Tax_Id=410289 (lytB2)SubName: Full=Probable
           lytB-related protein lytB2;[Mycobacterium bovis]
          Length = 335

 Score =  530 bits (1366), Expect = e-149
 Identities = 268/335 (80%), Positives = 289/335 (86%), Gaps = 3/335 (0%)

Query: 1   MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
           MVPT+DMGIPGAS    SVA  P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct: 1   MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60

Query: 58  RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
           RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct: 61  RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120

Query: 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
           CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D  ++VT+RDE
Sbjct: 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180

Query: 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXX 237
           +KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+   
Sbjct: 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240

Query: 238 XXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRG 297
                           ALGAGA+AA+LVDWADDID +WL           ASVPEVLVRG
Sbjct: 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300

Query: 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           VLERLAE GYD+VQPVTTANETLVFALPRE+R  R
Sbjct: 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335


>tr|A5WLD6|A5WLD6_MYCTF Tax_Id=336982 SubName: Full=LytB-related
           protein lytB2;[Mycobacterium tuberculosis]
          Length = 335

 Score =  530 bits (1366), Expect = e-149
 Identities = 268/335 (80%), Positives = 289/335 (86%), Gaps = 3/335 (0%)

Query: 1   MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
           MVPT+DMGIPGAS    SVA  P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct: 1   MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60

Query: 58  RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
           RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct: 61  RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120

Query: 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
           CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D  ++VT+RDE
Sbjct: 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180

Query: 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXX 237
           +KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+   
Sbjct: 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240

Query: 238 XXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRG 297
                           ALGAGA+AA+LVDWADDID +WL           ASVPEVLVRG
Sbjct: 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300

Query: 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           VLERLAE GYD+VQPVTTANETLVFALPRE+R  R
Sbjct: 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335


>tr|A4KG41|A4KG41_MYCTU Tax_Id=395095 SubName: Full=LytB-related
           protein lytB2;[Mycobacterium tuberculosis str. Haarlem]
          Length = 335

 Score =  530 bits (1366), Expect = e-149
 Identities = 268/335 (80%), Positives = 289/335 (86%), Gaps = 3/335 (0%)

Query: 1   MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
           MVPT+DMGIPGAS    SVA  P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct: 1   MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60

Query: 58  RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
           RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct: 61  RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120

Query: 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
           CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D  ++VT+RDE
Sbjct: 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180

Query: 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXX 237
           +KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+   
Sbjct: 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240

Query: 238 XXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRG 297
                           ALGAGA+AA+LVDWADDID +WL           ASVPEVLVRG
Sbjct: 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300

Query: 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           VLERLAE GYD+VQPVTTANETLVFALPRE+R  R
Sbjct: 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335


>tr|A2VH26|A2VH26_MYCTU Tax_Id=348776 SubName: Full=LytB-related
           protein lytB2;[Mycobacterium tuberculosis C]
          Length = 335

 Score =  530 bits (1366), Expect = e-149
 Identities = 268/335 (80%), Positives = 289/335 (86%), Gaps = 3/335 (0%)

Query: 1   MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
           MVPT+DMGIPGAS    SVA  P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct: 1   MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60

Query: 58  RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
           RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct: 61  RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120

Query: 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
           CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D  ++VT+RDE
Sbjct: 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180

Query: 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXX 237
           +KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+   
Sbjct: 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240

Query: 238 XXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRG 297
                           ALGAGA+AA+LVDWADDID +WL           ASVPEVLVRG
Sbjct: 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300

Query: 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           VLERLAE GYD+VQPVTTANETLVFALPRE+R  R
Sbjct: 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335


>sp|Q1B4H4|ISPH_MYCSS Tax_Id=164756 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium sp.]
          Length = 333

 Score =  499 bits (1285), Expect = e-139
 Identities = 252/332 (75%), Positives = 279/332 (84%)

Query: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60
           M PTI+MGIPGASSSV    + +RVLLAEPRGYCAGVDRAVETVERALEKHG PVYVRHE
Sbjct: 1   MPPTINMGIPGASSSVTGGVSGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRHE 60

Query: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120
           IVHNR+VVDTLAKAGAVFVE+TD+VPEGAIVVFSAHGVAPTV+  AA RNL+TIDATCPL
Sbjct: 61  IVHNRYVVDTLAKAGAVFVEQTDEVPEGAIVVFSAHGVAPTVHVEAAARNLKTIDATCPL 120

Query: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180
           VTKVHNEA+RFAR+DYDILL+GHEGHEEVVGTAGEAP+HVQ+VD  D  ++VT+RD +KV
Sbjct: 121 VTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDKVTVRDPDKV 180

Query: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXX 240
           +WLSQTTLSVDETME V RLR++FP LQDPPSDDICYATQNRQVAVKAMAPEC+      
Sbjct: 181 IWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELVIVVG 240

Query: 241 XXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLE 300
                        ALGAG+ AA+LVD+A+DID +WL           ASVPEVLVRGVL+
Sbjct: 241 SKNSSNSVRLVEVALGAGSDAAHLVDYAEDIDPTWLNGVTTVGVTSGASVPEVLVRGVLD 300

Query: 301 RLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           RLAE GY  VQPVTTANETLVFALPREIRPAR
Sbjct: 301 RLAEYGYGTVQPVTTANETLVFALPREIRPAR 332


>sp|A1UKL5|ISPH_MYCSK Tax_Id=189918 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium sp.]
          Length = 333

 Score =  499 bits (1285), Expect = e-139
 Identities = 252/332 (75%), Positives = 279/332 (84%)

Query: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60
           M PTI+MGIPGASSSV    + +RVLLAEPRGYCAGVDRAVETVERALEKHG PVYVRHE
Sbjct: 1   MPPTINMGIPGASSSVTGGVSGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRHE 60

Query: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120
           IVHNR+VVDTLAKAGAVFVE+TD+VPEGAIVVFSAHGVAPTV+  AA RNL+TIDATCPL
Sbjct: 61  IVHNRYVVDTLAKAGAVFVEQTDEVPEGAIVVFSAHGVAPTVHVEAAARNLKTIDATCPL 120

Query: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180
           VTKVHNEA+RFAR+DYDILL+GHEGHEEVVGTAGEAP+HVQ+VD  D  ++VT+RD +KV
Sbjct: 121 VTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDKVTVRDPDKV 180

Query: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXX 240
           +WLSQTTLSVDETME V RLR++FP LQDPPSDDICYATQNRQVAVKAMAPEC+      
Sbjct: 181 IWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELVIVVG 240

Query: 241 XXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLE 300
                        ALGAG+ AA+LVD+A+DID +WL           ASVPEVLVRGVL+
Sbjct: 241 SKNSSNSVRLVEVALGAGSDAAHLVDYAEDIDPTWLNGVTTVGVTSGASVPEVLVRGVLD 300

Query: 301 RLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           RLAE GY  VQPVTTANETLVFALPREIRPAR
Sbjct: 301 RLAEYGYGTVQPVTTANETLVFALPREIRPAR 332


>sp|A3Q4N0|ISPH_MYCSJ Tax_Id=164757 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium sp.]
          Length = 333

 Score =  499 bits (1285), Expect = e-139
 Identities = 252/332 (75%), Positives = 279/332 (84%)

Query: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60
           M PTI+MGIPGASSSV    + +RVLLAEPRGYCAGVDRAVETVERALEKHG PVYVRHE
Sbjct: 1   MPPTINMGIPGASSSVTGGVSGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRHE 60

Query: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120
           IVHNR+VVDTLAKAGAVFVE+TD+VPEGAIVVFSAHGVAPTV+  AA RNL+TIDATCPL
Sbjct: 61  IVHNRYVVDTLAKAGAVFVEQTDEVPEGAIVVFSAHGVAPTVHVEAAARNLKTIDATCPL 120

Query: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180
           VTKVHNEA+RFAR+DYDILL+GHEGHEEVVGTAGEAP+HVQ+VD  D  ++VT+RD +KV
Sbjct: 121 VTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDKVTVRDPDKV 180

Query: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXX 240
           +WLSQTTLSVDETME V RLR++FP LQDPPSDDICYATQNRQVAVKAMAPEC+      
Sbjct: 181 IWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELVIVVG 240

Query: 241 XXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLE 300
                        ALGAG+ AA+LVD+A+DID +WL           ASVPEVLVRGVL+
Sbjct: 241 SKNSSNSVRLVEVALGAGSDAAHLVDYAEDIDPTWLDGVTTVGVTSGASVPEVLVRGVLD 300

Query: 301 RLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           RLAE GY  VQPVTTANETLVFALPREIRPAR
Sbjct: 301 RLAEYGYGTVQPVTTANETLVFALPREIRPAR 332


>sp|A4T986|ISPH_MYCGI Tax_Id=350054 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium gilvum]
          Length = 333

 Score =  496 bits (1276), Expect = e-138
 Identities = 246/332 (74%), Positives = 277/332 (83%)

Query: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60
           M PT++MGIPGA+SSV      +RVLLAEPRGYCAGVDRAVETVERALEKHG P+YVRHE
Sbjct: 1   MPPTVNMGIPGAASSVVERTAGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPIYVRHE 60

Query: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120
           IVHNR+VVDTLAKAGA+FVE+TD+VPEGAIVVFSAHGVAPTV+  AA RNL+TIDATCPL
Sbjct: 61  IVHNRYVVDTLAKAGAIFVEQTDEVPEGAIVVFSAHGVAPTVHVEAAARNLKTIDATCPL 120

Query: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180
           VTKVHNEA+RFAR+DYDILL+GHEGHEEVVGTAGEAP+HVQ+VD  D  + V +RD  KV
Sbjct: 121 VTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDNVVVRDPNKV 180

Query: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXX 240
           +WLSQTTLSVDETME V RLR++FP LQDPPSDDICYATQNRQVAVKAMAPEC+      
Sbjct: 181 IWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELVIVVG 240

Query: 241 XXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLE 300
                        ALGAG++AA+LVD+A+DID +WL           ASVPE+LVRGVL+
Sbjct: 241 SKNSSNSVRLVEVALGAGSRAAHLVDYAEDIDPAWLDGVTTVGVTSGASVPEILVRGVLD 300

Query: 301 RLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           RLAE G+D VQPVTTANETLVFALPREIRPAR
Sbjct: 301 RLAEHGFDTVQPVTTANETLVFALPREIRPAR 332


>sp|A1TE06|ISPH_MYCVP Tax_Id=350058 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium vanbaalenii]
          Length = 337

 Score =  495 bits (1275), Expect = e-138
 Identities = 250/336 (74%), Positives = 279/336 (83%), Gaps = 4/336 (1%)

Query: 1   MVPTIDMGIPGAS----SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVY 56
           M PT++MGIPGAS     SVA   T +RVLLAEPRGYCAGVDRAVETVERALEKHG P+Y
Sbjct: 1   MPPTVNMGIPGASRTALGSVAGDVTGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPIY 60

Query: 57  VRHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDA 116
           VRHEIVHNR+VVDTLAKAGA+FVE+TD+VPEGAIVVFSAHGVAPTV+  AA R+L+TIDA
Sbjct: 61  VRHEIVHNRYVVDTLAKAGAIFVEQTDEVPEGAIVVFSAHGVAPTVHEEAAARHLRTIDA 120

Query: 117 TCPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRD 176
           TCPLVTKVHNEA+RFAR+DYDILL+GHEGHEEVVGTAGEAP+HVQ+VD  D  ++VT+RD
Sbjct: 121 TCPLVTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDKVTVRD 180

Query: 177 EEKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXX 236
             KV+WLSQTTLSVDETME V RLR++FP LQDPPSDDICYATQNRQVAVKAMAPEC+  
Sbjct: 181 PNKVIWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELV 240

Query: 237 XXXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVR 296
                            ALGAGA AA+LVD+ADDID +W            ASVPE+LVR
Sbjct: 241 IVVGSKNSSNSVRLVEVALGAGASAAHLVDYADDIDPAWFDGVTTVGVTSGASVPEILVR 300

Query: 297 GVLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           GVL+RLAE GYD+VQPVTTANETLVFALPREIRPAR
Sbjct: 301 GVLDRLAEHGYDVVQPVTTANETLVFALPREIRPAR 336


>sp|Q9X781|ISPH_MYCLE Tax_Id=1769 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium leprae]
          Length = 332

 Score =  495 bits (1275), Expect = e-138
 Identities = 249/331 (75%), Positives = 273/331 (82%)

Query: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60
           M PT++MGIPGAS S+     R+RVLLAEPRGYCAGVDRAVETVER+L K+GPPVYVRHE
Sbjct: 1   MPPTVNMGIPGASRSIVENLKRKRVLLAEPRGYCAGVDRAVETVERSLRKYGPPVYVRHE 60

Query: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120
           IVHNRHVV+TL +AGAVFVEETD VPEGAIV+FSAHGVAPTVYAAAAERNL+TIDATCPL
Sbjct: 61  IVHNRHVVETLERAGAVFVEETDYVPEGAIVIFSAHGVAPTVYAAAAERNLRTIDATCPL 120

Query: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180
           VTKVHNE +RFARNDYDILLIGHEGHEEV+ TAGEAP HVQLVDGL   ++V +RDE KV
Sbjct: 121 VTKVHNEVKRFARNDYDILLIGHEGHEEVIATAGEAPTHVQLVDGLAAVQQVVVRDENKV 180

Query: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXX 240
           VWLSQTTLSVDETM IV RLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPEC+      
Sbjct: 181 VWLSQTTLSVDETMRIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVG 240

Query: 241 XXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLE 300
                        A+G+GA AAYLVDWA DID +WL           ASVP++LV+GVL+
Sbjct: 241 SRNSSNSVRLVEVAMGSGAGAAYLVDWAKDIDPAWLAGVTTVGVTSGASVPDILVQGVLK 300

Query: 301 RLAESGYDMVQPVTTANETLVFALPREIRPA 331
            LAE GYD+VQ VTTANE LVFALPREIR A
Sbjct: 301 WLAERGYDVVQSVTTANEALVFALPREIRSA 331


>tr|B8ZSG0|B8ZSG0_MYCLB Tax_Id=561304 (lytB2)SubName: Full=LytB
           homolog;[Mycobacterium leprae]
          Length = 335

 Score =  495 bits (1275), Expect = e-138
 Identities = 249/331 (75%), Positives = 273/331 (82%)

Query: 1   MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHE 60
           M PT++MGIPGAS S+     R+RVLLAEPRGYCAGVDRAVETVER+L K+GPPVYVRHE
Sbjct: 4   MPPTVNMGIPGASRSIVENLKRKRVLLAEPRGYCAGVDRAVETVERSLRKYGPPVYVRHE 63

Query: 61  IVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPL 120
           IVHNRHVV+TL +AGAVFVEETD VPEGAIV+FSAHGVAPTVYAAAAERNL+TIDATCPL
Sbjct: 64  IVHNRHVVETLERAGAVFVEETDYVPEGAIVIFSAHGVAPTVYAAAAERNLRTIDATCPL 123

Query: 121 VTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKV 180
           VTKVHNE +RFARNDYDILLIGHEGHEEV+ TAGEAP HVQLVDGL   ++V +RDE KV
Sbjct: 124 VTKVHNEVKRFARNDYDILLIGHEGHEEVIATAGEAPTHVQLVDGLAAVQQVVVRDENKV 183

Query: 181 VWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXX 240
           VWLSQTTLSVDETM IV RLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPEC+      
Sbjct: 184 VWLSQTTLSVDETMRIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVG 243

Query: 241 XXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLE 300
                        A+G+GA AAYLVDWA DID +WL           ASVP++LV+GVL+
Sbjct: 244 SRNSSNSVRLVEVAMGSGAGAAYLVDWAKDIDPAWLAGVTTVGVTSGASVPDILVQGVLK 303

Query: 301 RLAESGYDMVQPVTTANETLVFALPREIRPA 331
            LAE GYD+VQ VTTANE LVFALPREIR A
Sbjct: 304 WLAERGYDVVQSVTTANEALVFALPREIRSA 334


>tr|A0R2T2|A0R2T2_MYCS2 Tax_Id=246196 (ispH)SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium smegmatis]
          Length = 314

 Score =  481 bits (1238), Expect = e-134
 Identities = 240/310 (77%), Positives = 263/310 (84%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           +RVLLAEPRGYCAGVDRAVETVERALEKHG PVYVRHEIVHNRHVV+TLAKAGA+FV+ET
Sbjct: 4   KRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRHEIVHNRHVVETLAKAGAIFVDET 63

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           D+VPEGAIVVFSAHGVAPTV+ +AAERNL+ IDATCPLVTKVHNEA+RFAR+DYDILLIG
Sbjct: 64  DEVPEGAIVVFSAHGVAPTVHQSAAERNLKVIDATCPLVTKVHNEAKRFARDDYDILLIG 123

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           HEGHEEVVGTAGEAP+HVQLVDG +  + VT+RDE KV+WLSQTTLSVDETME V RLR+
Sbjct: 124 HEGHEEVVGTAGEAPDHVQLVDGPESVDAVTVRDESKVIWLSQTTLSVDETMETVRRLRE 183

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           +FP LQDPPSDDICYATQNRQVAVKAMAPEC+                   AL AG+ AA
Sbjct: 184 KFPTLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALNAGSDAA 243

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           +LVD+ADDID +WL           ASVPE+LVRGVLERLAE GYD VQPVTTANETLVF
Sbjct: 244 HLVDYADDIDPAWLDGVTTIGVTSGASVPEILVRGVLERLAEHGYDTVQPVTTANETLVF 303

Query: 323 ALPREIRPAR 332
           ALPREIRP R
Sbjct: 304 ALPREIRPPR 313


>tr|B1MKQ3|B1MKQ3_MYCA9 Tax_Id=561007 SubName: Full=Probable
           4-hydroxy-3-methylbut-2-enyl diphosphate
           reductase;[Mycobacterium abscessus]
          Length = 337

 Score =  479 bits (1233), Expect = e-133
 Identities = 242/331 (73%), Positives = 271/331 (81%), Gaps = 3/331 (0%)

Query: 5   IDMGIPGASSSVAHV---PTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEI 61
           +DMG PG  S+          +RVLLAEPRGYCAGVDRAVETVERALEKHG PVYVRHEI
Sbjct: 4   VDMGTPGMVSTAMRTVGPAISKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRHEI 63

Query: 62  VHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLV 121
           VHNR+VVDTLAKAGA+FV+ETD+VPEGAIVVFSAHGVAPTV+  AAERNL+TIDATCPLV
Sbjct: 64  VHNRYVVDTLAKAGAIFVDETDEVPEGAIVVFSAHGVAPTVHEKAAERNLKTIDATCPLV 123

Query: 122 TKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVV 181
           TKVH EA+RFAR+D+DILLIGHEGHEEV+GTAGEAP+HVQLVDG +  + VT+RDE KV+
Sbjct: 124 TKVHQEAKRFARDDFDILLIGHEGHEEVIGTAGEAPDHVQLVDGPNAVDNVTVRDENKVI 183

Query: 182 WLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXX 241
           WLSQTTLSVDETME V RLR+RFP LQDPPSDDICYATQNRQVAVKAMAPEC+       
Sbjct: 184 WLSQTTLSVDETMETVQRLRERFPTLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGS 243

Query: 242 XXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLER 301
                       AL AG++A+YLVD+A+DID +WL+          ASVPEVLVRGVLER
Sbjct: 244 RNSSNSVRLVEVALNAGSRASYLVDYAEDIDPAWLEGVTTVGVTSGASVPEVLVRGVLER 303

Query: 302 LAESGYDMVQPVTTANETLVFALPREIRPAR 332
           LAE GY  VQPVTTANETLVFALPRE+R +R
Sbjct: 304 LAEHGYGEVQPVTTANETLVFALPRELRASR 334


>tr|A0QC38|A0QC38_MYCA1 Tax_Id=243243 (ispH)SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Mycobacterium avium]
          Length = 296

 Score =  471 bits (1213), Expect = e-131
 Identities = 239/296 (80%), Positives = 253/296 (85%)

Query: 37  VDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAH 96
           +DRAVETVERALEKHGPPVYVRHEIVHNRHVV TL KAGAVFVEETD+VPEGAIVVFSAH
Sbjct: 1   MDRAVETVERALEKHGPPVYVRHEIVHNRHVVSTLEKAGAVFVEETDEVPEGAIVVFSAH 60

Query: 97  GVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEA 156
           GVAPTV+AAAAERNL TIDATCPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEA
Sbjct: 61  GVAPTVHAAAAERNLHTIDATCPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEA 120

Query: 157 PEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDIC 216
           P+HVQLVDG+   + VT+RDE+KVVWLSQTTLSVDETMEIV RLRQRFPKLQDPPSDDIC
Sbjct: 121 PDHVQLVDGVAAVDNVTVRDEDKVVWLSQTTLSVDETMEIVERLRQRFPKLQDPPSDDIC 180

Query: 217 YATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWL 276
           YATQNRQVAVKAMAPECD                   ALG GA AA+LVDWADDID +WL
Sbjct: 181 YATQNRQVAVKAMAPECDLVIVVGSRNSSNSVRLVEVALGGGAGAAHLVDWADDIDPAWL 240

Query: 277 QXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           +          ASVPEVLV+GVLERLAE G+D+VQPVTTA ETLVFALPREIR AR
Sbjct: 241 EGVTTVGVTSGASVPEVLVQGVLERLAECGFDVVQPVTTAQETLVFALPREIRSAR 296


>sp|C1A2V7|ISPH_RHOE4 Tax_Id=234621 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Rhodococcus erythropolis]
          Length = 337

 Score =  454 bits (1168), Expect = e-126
 Identities = 228/329 (69%), Positives = 264/329 (80%), Gaps = 1/329 (0%)

Query: 5   IDMGIP-GASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVH 63
           +++GI   A S      + +RVLLAEPRGYCAGVDRAVETVE+ALEKHG P+YVR EIVH
Sbjct: 7   LNLGIAHSADSPSTRKGSAKRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEIVH 66

Query: 64  NRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTK 123
           NRHVV+TL   G +FV+ETD+VPEG+++VFSAHGV+P V+ +AAERNL+TIDATCPLVTK
Sbjct: 67  NRHVVETLEDQGVIFVDETDEVPEGSLLVFSAHGVSPAVHDSAAERNLRTIDATCPLVTK 126

Query: 124 VHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWL 183
           VH EA+RFAR+DYDILLIGHEGHEEV GTAGEAP+HV +VDG D  + VT+RDE KV+WL
Sbjct: 127 VHQEAKRFARDDYDILLIGHEGHEEVEGTAGEAPDHVTIVDGPDSVDAVTVRDESKVIWL 186

Query: 184 SQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXX 243
           SQTTLSVDETM+ VARLR+RFP LQDPPSDDICYATQNRQVAVKAMAPECD         
Sbjct: 187 SQTTLSVDETMQTVARLRERFPNLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRN 246

Query: 244 XXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLA 303
                     ALGAGA A+YLVD+A ++D +WL+          ASVPEVLVRGV+E LA
Sbjct: 247 SSNSVRLVEVALGAGAAASYLVDYAREVDLAWLEGVQTVGITSGASVPEVLVRGVIELLA 306

Query: 304 ESGYDMVQPVTTANETLVFALPREIRPAR 332
           E GY+ VQPVTTANETLVFALPRE+R AR
Sbjct: 307 EHGYNDVQPVTTANETLVFALPRELRAAR 335


>tr|C3JU01|C3JU01_RHOER Tax_Id=596309 (ispH)SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Rhodococcus erythropolis SK121]
          Length = 337

 Score =  454 bits (1168), Expect = e-126
 Identities = 228/329 (69%), Positives = 264/329 (80%), Gaps = 1/329 (0%)

Query: 5   IDMGIP-GASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVH 63
           +++GI   A S      + +RVLLAEPRGYCAGVDRAVETVE+ALEKHG P+YVR EIVH
Sbjct: 7   LNLGIAHSADSPSTRKGSAKRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEIVH 66

Query: 64  NRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTK 123
           NRHVV+TL   G +FV+ETD+VPEG+++VFSAHGV+P V+ +AAERNL+TIDATCPLVTK
Sbjct: 67  NRHVVETLEDQGVIFVDETDEVPEGSLLVFSAHGVSPAVHDSAAERNLRTIDATCPLVTK 126

Query: 124 VHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWL 183
           VH EA+RFAR+DYDILLIGHEGHEEV GTAGEAP+HV +VDG D  + VT+RDE KV+WL
Sbjct: 127 VHQEAKRFARDDYDILLIGHEGHEEVEGTAGEAPDHVTIVDGPDSVDAVTVRDESKVIWL 186

Query: 184 SQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXX 243
           SQTTLSVDETM+ VARLR+RFP LQDPPSDDICYATQNRQVAVKAMAPECD         
Sbjct: 187 SQTTLSVDETMQTVARLRERFPNLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRN 246

Query: 244 XXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLA 303
                     ALGAGA A+YLVD+A ++D +WL+          ASVPEVLVRGV+E LA
Sbjct: 247 SSNSVRLVEVALGAGAAASYLVDYAREVDLAWLEGVQTVGITSGASVPEVLVRGVIELLA 306

Query: 304 ESGYDMVQPVTTANETLVFALPREIRPAR 332
           E GY+ VQPVTTANETLVFALPRE+R AR
Sbjct: 307 EHGYNDVQPVTTANETLVFALPRELRAAR 335


>sp|Q5YQ94|ISPH_NOCFA Tax_Id=37329 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Nocardia farcinica]
          Length = 336

 Score =  453 bits (1166), Expect = e-125
 Identities = 229/329 (69%), Positives = 261/329 (79%), Gaps = 1/329 (0%)

Query: 5   IDMGIP-GASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVH 63
           +++GI   A ++     T +RVLLAEPRGYCAGVDRAVETVE+ALEKHG P+YVR EIVH
Sbjct: 7   LNVGIARSAGTATVDADTAKRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEIVH 66

Query: 64  NRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTK 123
           NRHVV+TL + G VFV++T +VPEGA+VVFSAHGV+P V+ AAA RNL TIDATCPLVTK
Sbjct: 67  NRHVVETLRERGVVFVDDTAEVPEGAVVVFSAHGVSPAVHEAAAARNLHTIDATCPLVTK 126

Query: 124 VHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWL 183
           VH EA+RFAR+DYDILLIGHEGHEEV GTAGEAPEHVQLVDG D  +RV +RDE KV+WL
Sbjct: 127 VHQEAKRFARDDYDILLIGHEGHEEVEGTAGEAPEHVQLVDGPDAVDRVRVRDENKVIWL 186

Query: 184 SQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXX 243
           SQTTLSVDETME V RLR+RFP LQDPPSDDICYATQNRQVAVKAMAPECD         
Sbjct: 187 SQTTLSVDETMETVQRLRERFPSLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRN 246

Query: 244 XXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLA 303
                     AL AGA+AA+LVD+A ++D +WL+          ASVPE+LVRGVL+ LA
Sbjct: 247 SSNSVRLVEVALNAGAKAAHLVDYAREVDPAWLEGVRTIGITSGASVPEILVRGVLDMLA 306

Query: 304 ESGYDMVQPVTTANETLVFALPREIRPAR 332
           E GY  VQPVTTANETLVFALPRE+R  R
Sbjct: 307 EHGYADVQPVTTANETLVFALPRELRTTR 335


>sp|C1AYI4|ISPH_RHOOB Tax_Id=632772 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Rhodococcus opacus]
          Length = 336

 Score =  452 bits (1162), Expect = e-125
 Identities = 226/329 (68%), Positives = 263/329 (79%), Gaps = 1/329 (0%)

Query: 5   IDMGIP-GASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVH 63
           +++GI   A S  +     +RVLLAEPRGYCAGVDRAVETVE+ALEKHG P+YVR EIVH
Sbjct: 7   LNVGITRSADSGASRADGEKRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEIVH 66

Query: 64  NRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTK 123
           NRHVV+TL+  G VFV+ETD+VPEGA++VFSAHGV+P V+ +AA RNL+TIDATCPLVTK
Sbjct: 67  NRHVVETLSDQGVVFVDETDEVPEGALLVFSAHGVSPAVHESAAARNLRTIDATCPLVTK 126

Query: 124 VHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWL 183
           VH EA+RFAR+D+DILLIGHEGHEEV GTAGEAP+HVQLVDG D  + VT+RDE KV+WL
Sbjct: 127 VHQEAKRFARDDFDILLIGHEGHEEVEGTAGEAPDHVQLVDGPDSVDAVTVRDESKVIWL 186

Query: 184 SQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXX 243
           SQTTLSVDETM+ VARLR+RFP LQDPPSDDICYATQNRQVAVKAMAPECD         
Sbjct: 187 SQTTLSVDETMQTVARLRERFPSLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRN 246

Query: 244 XXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLA 303
                     ALGAGA+A+YLVD+A ++D +WL           ASVPE+LVRGV++ L 
Sbjct: 247 SSNSVRLVEVALGAGAKASYLVDYAREVDPAWLDGVRTVGITSGASVPEILVRGVIDLLD 306

Query: 304 ESGYDMVQPVTTANETLVFALPREIRPAR 332
           E G+  VQPVTTANETLVFALPRE+R AR
Sbjct: 307 EHGFHDVQPVTTANETLVFALPRELRAAR 335


>sp|Q0S489|ISPH_RHOSR Tax_Id=101510 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Rhodococcus sp.]
          Length = 336

 Score =  451 bits (1159), Expect = e-125
 Identities = 226/329 (68%), Positives = 261/329 (79%), Gaps = 1/329 (0%)

Query: 5   IDMGIP-GASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVH 63
           +++GI   A S  +     +RVLLAEPRGYCAGVDRAVETVE+ALEKHG P+YVR EIVH
Sbjct: 7   LNVGITRSADSGASRADGEKRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEIVH 66

Query: 64  NRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTK 123
           NRHVVDTL   G VFV+ETD+VPEGA++VFSAHGV+P V+ +AA RNL+TIDATCPLVTK
Sbjct: 67  NRHVVDTLTDQGVVFVDETDEVPEGALLVFSAHGVSPAVHESAAARNLRTIDATCPLVTK 126

Query: 124 VHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWL 183
           VH EA+RFAR+D+DILLIGHEGHEEV GTAGEAP+HVQLVDG D  + VT+RDE KV+WL
Sbjct: 127 VHQEAKRFARDDFDILLIGHEGHEEVEGTAGEAPDHVQLVDGPDSVDAVTVRDESKVIWL 186

Query: 184 SQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXX 243
           SQTTLSVDETM+ VARLR+RFP LQDPPSDDICYATQNRQVAVKAMAPECD         
Sbjct: 187 SQTTLSVDETMQTVARLRERFPNLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRN 246

Query: 244 XXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLA 303
                     AL AGA+A+YLVD+A ++D +WL           ASVPE+LVRGV++ L 
Sbjct: 247 SSNSVRLVEVALNAGAKASYLVDYAREVDPAWLDGVRTVGITSGASVPEILVRGVIDLLD 306

Query: 304 ESGYDMVQPVTTANETLVFALPREIRPAR 332
           E G+  VQPVTTANETLVFALPRE+R AR
Sbjct: 307 EHGFHDVQPVTTANETLVFALPRELRAAR 335


>tr|D0L7T7|D0L7T7_GORB4 Tax_Id=526226 SubName:
           Full=Hydroxymethylbutenyl pyrophosphate reductase;
           EC=1.17.1.2;[Gordonia bronchialis]
          Length = 317

 Score =  438 bits (1127), Expect = e-121
 Identities = 220/310 (70%), Positives = 249/310 (80%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           +RVLLAEPRGYCAGVDRAVETVERAL+KHG PVYVR EIVHNRHVV+TL+  GAVFV ET
Sbjct: 5   KRVLLAEPRGYCAGVDRAVETVERALDKHGAPVYVRKEIVHNRHVVETLSDRGAVFVGET 64

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           D+VPEGAIVVFSAHGV+P V+  AA R+L+TIDATCPLVTKVH EA+RFAR+DYDILLIG
Sbjct: 65  DEVPEGAIVVFSAHGVSPEVHRTAAARSLKTIDATCPLVTKVHQEAKRFARDDYDILLIG 124

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           HEGHEEV GTAGEAPEH+QLVDG D  ++V++RDE KV+WLSQTTLSVDETME V RLR+
Sbjct: 125 HEGHEEVEGTAGEAPEHIQLVDGPDSVDKVSVRDESKVIWLSQTTLSVDETMETVKRLRE 184

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           +FP+L DPPSDDICYATQNRQVAVKAMAP CD                   A+  GA A 
Sbjct: 185 KFPQLADPPSDDICYATQNRQVAVKAMAPHCDLVIVVGSTNSSNSVRLVEVAVQNGASAG 244

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           +LVD+A +ID +WL+          ASVPEVLVRGVL+ LAE GYD V+ V TA ETL F
Sbjct: 245 HLVDYAREIDPAWLEGVNTVGVTSGASVPEVLVRGVLDYLAERGYDSVETVNTAEETLTF 304

Query: 323 ALPREIRPAR 332
           ALPRE+RPAR
Sbjct: 305 ALPRELRPAR 314


>tr|C2AV51|C2AV51_TSUPA Tax_Id=521096 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Tsukamurella paurometabola DSM 20162]
          Length = 316

 Score =  438 bits (1126), Expect = e-121
 Identities = 217/308 (70%), Positives = 251/308 (81%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           +RVLLAEPRGYCAGVDRAVETVE+ALEKHG PVYVR EIVHNRHVV+TL   G +FV+ET
Sbjct: 5   KRVLLAEPRGYCAGVDRAVETVEKALEKHGAPVYVRKEIVHNRHVVETLQDKGVIFVDET 64

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           D+VPEG+++VFSAHGV+P V+A A +R+L+TIDATCPLVTKVH EA+RFAR+D+DILLIG
Sbjct: 65  DEVPEGSLLVFSAHGVSPAVHAGAEQRSLRTIDATCPLVTKVHQEAKRFARDDFDILLIG 124

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           HEGHEEV GTAGEAPEHVQLVDG D  + V +RDEEK+VWLSQTTLSVDETME V RLR+
Sbjct: 125 HEGHEEVEGTAGEAPEHVQLVDGPDAVDAVQVRDEEKIVWLSQTTLSVDETMETVRRLRE 184

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           +FPKLQDPPSDDICYATQNRQVAVKAMAPECD                   AL AGA+AA
Sbjct: 185 KFPKLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRNSSNSVRLVEVALQAGARAA 244

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           +L+D+A +ID +WL           ASVPE+LV+GV+E L   G+  V+PVTTANETLVF
Sbjct: 245 HLIDFAREIDPAWLDGVQTVGITSGASVPEILVKGVVEYLDGEGFHDVKPVTTANETLVF 304

Query: 323 ALPREIRP 330
           ALPRE+RP
Sbjct: 305 ALPRELRP 312


>tr|C7MYN2|C7MYN2_SACVD Tax_Id=471857 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Saccharomonospora viridis]
          Length = 327

 Score =  407 bits (1047), Expect = e-112
 Identities = 203/316 (64%), Positives = 245/316 (77%)

Query: 14  SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAK 73
           S+ +     +RVLLA+PRGYCAGVDRAV TVE+ALEK+GPP+YVR EIVHN++VVDTL K
Sbjct: 2   STASPTSNGKRVLLAKPRGYCAGVDRAVVTVEKALEKYGPPIYVRKEIVHNKYVVDTLRK 61

Query: 74  AGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFAR 133
            G +FV+ET +VPEG++VVFSAHGV+P V+A AAERNL+TIDATCPLVTKVH E  RFAR
Sbjct: 62  RGVIFVDETSEVPEGSLVVFSAHGVSPAVHAEAAERNLRTIDATCPLVTKVHREVVRFAR 121

Query: 134 NDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDET 193
           +DYDILLIGHEGHEEV GTAGEAP+ VQLVD  +   +VT+RD  KVVW+SQTTLSVDET
Sbjct: 122 DDYDILLIGHEGHEEVEGTAGEAPDRVQLVDTPEDVHKVTVRDPSKVVWVSQTTLSVDET 181

Query: 194 MEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXX 253
           ME V +L++RFP+L DPPS+DICYAT NRQ AVKAMAPECD                   
Sbjct: 182 MERVNQLKERFPELADPPSEDICYATSNRQTAVKAMAPECDLVLVVGSQNSSNSKRLVEV 241

Query: 254 ALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPV 313
           AL AGA+ A+L+D+A ++D+ WL+          ASVP+VLV  +LE+LAE G+D VQ V
Sbjct: 242 ALQAGARDAHLIDYAHEVDEKWLEGVETIGVTSGASVPDVLVMELLEKLAERGWDDVQEV 301

Query: 314 TTANETLVFALPREIR 329
           TTANE + FALPRE+R
Sbjct: 302 TTANEKITFALPRELR 317


>tr|C6WKT7|C6WKT7_ACTMD Tax_Id=446462 SubName:
           Full=Hydroxymethylbutenyl pyrophosphate reductase;
           EC=1.17.1.2;[Actinosynnema mirum]
          Length = 314

 Score =  407 bits (1045), Expect = e-111
 Identities = 198/307 (64%), Positives = 242/307 (78%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           +RVLLA PRGYCAGVDRAV TVE+ALEK+G PVYVR EIVHN+HVV+TL+K GA+FV ET
Sbjct: 3   KRVLLANPRGYCAGVDRAVVTVEKALEKYGAPVYVRKEIVHNKHVVETLSKRGAIFVNET 62

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           D+VPEGA+VVFSAHGV+P V+  AA+R+L+TIDATCPLVTKVH EA+RFAR DYDILLIG
Sbjct: 63  DEVPEGALVVFSAHGVSPKVHEEAADRSLRTIDATCPLVTKVHKEAQRFAREDYDILLIG 122

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           HEGHEEV GTAGEAP+H+QLVD  +   +V +RD  KV+WLSQTTLSVDETM  V +L++
Sbjct: 123 HEGHEEVEGTAGEAPDHIQLVDTAEDVAKVEVRDPSKVIWLSQTTLSVDETMVRVRQLKE 182

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           RFP LQ+PPSDDICYAT NRQVAVK MAPECD                   AL AGA+A+
Sbjct: 183 RFPDLQEPPSDDICYATSNRQVAVKTMAPECDLVLVVGSKNSSNSVRLVEVALQAGAKAS 242

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           YL+D+A+++D++WL+          ASVP++LV  +L+ LAE GY  V+ +TTANE + F
Sbjct: 243 YLIDYAEEVDEAWLEGVGTVGVTSGASVPDILVMDLLKHLAERGYGDVEEITTANEKIAF 302

Query: 323 ALPREIR 329
           +LPRE+R
Sbjct: 303 SLPRELR 309


>tr|A3TGX7|A3TGX7_9MICO Tax_Id=313589 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Janibacter sp. HTCC2649]
          Length = 341

 Score =  403 bits (1036), Expect = e-110
 Identities = 203/307 (66%), Positives = 237/307 (77%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           +RVLLA PRGYCAGVDRAV TVE+AL+ +G PVYVR EIVHN+HVV TL K GA+FVEET
Sbjct: 10  KRVLLAAPRGYCAGVDRAVVTVEKALDLYGAPVYVRKEIVHNKHVVTTLEKRGAIFVEET 69

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           D+VPEG+ V+FSAHGVAP V+  A    L+TIDATCPLVTKVH EA RFA +D+DILLIG
Sbjct: 70  DEVPEGSTVIFSAHGVAPVVHEEAKALGLKTIDATCPLVTKVHREAVRFASDDFDILLIG 129

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           HEGHEEVVGTAGEAPEH+ LV+G D  + V +RD +KVVWLSQTTLSVDETME V RLRQ
Sbjct: 130 HEGHEEVVGTAGEAPEHITLVEGPDSVDGVEVRDPDKVVWLSQTTLSVDETMETVRRLRQ 189

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           +FP +QDPPSDDICYATQNRQ+AVK MAP+CD                   AL  G++A 
Sbjct: 190 KFPLMQDPPSDDICYATQNRQLAVKHMAPDCDLMIVVGSRNSSNSVRLVEVALEHGSKAG 249

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           YLVD+AD+I++SWL           ASVPE+LVRGVL+ LAE GY+ V+PV  A E+LVF
Sbjct: 250 YLVDYADEIEESWLDGVGTVGVTSGASVPELLVRGVLDYLAERGYEDVRPVRAAEESLVF 309

Query: 323 ALPREIR 329
           +LP EIR
Sbjct: 310 SLPNEIR 316


>tr|C1WEF1|C1WEF1_9ACTO Tax_Id=479435 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Kribbella flavida DSM 17836]
          Length = 340

 Score =  399 bits (1026), Expect = e-109
 Identities = 201/307 (65%), Positives = 232/307 (75%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           +RVLLA PRGYCAGVDRAV  VE+AL+ +GPPVYVR EIVHN+HVV TL   GA+FV+ET
Sbjct: 17  KRVLLAAPRGYCAGVDRAVVAVEKALDLYGPPVYVRKEIVHNKHVVQTLQARGAIFVDET 76

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           D+VPEG  V+FSAHGVAP V+  AA R L+TIDATCPLVTKVH+EA+RFA  DYDILLIG
Sbjct: 77  DEVPEGETVIFSAHGVAPVVHQEAAARQLKTIDATCPLVTKVHHEAKRFAATDYDILLIG 136

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           HEGHEEV+GT+GEAPEH+ LVDG      V +RD EKVVWLSQTTLSVDETME V RLR+
Sbjct: 137 HEGHEEVIGTSGEAPEHIHLVDGPGDVPNVEVRDPEKVVWLSQTTLSVDETMETVRRLRE 196

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           RFP LQDPPSDDICYATQNRQ AVK +A + D                   A+  GA+A 
Sbjct: 197 RFPHLQDPPSDDICYATQNRQAAVKKLAADADLMIVVGSRNSSNSVRLVEVAVEHGAKAG 256

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           YLVD+AD+ID++WL+          ASVPE+LVR VL+ LA  GY  VQ VTTA E+L F
Sbjct: 257 YLVDYADEIDEAWLEGVDSVGVTSGASVPEILVRDVLDWLAARGYGEVQEVTTAEESLTF 316

Query: 323 ALPREIR 329
           ALPRE+R
Sbjct: 317 ALPRELR 323


>tr|D1BKR9|D1BKR9_9MICO Tax_Id=446469 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Sanguibacter keddieii DSM 10542]
          Length = 353

 Score =  398 bits (1023), Expect = e-109
 Identities = 199/306 (65%), Positives = 235/306 (76%)

Query: 24  RVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETD 83
           RVLLA PRGYCAGVDRAV  VE+AL  HG P+YVR EIVHN++VV+TL+  GA+FV+ETD
Sbjct: 22  RVLLAAPRGYCAGVDRAVIAVEKALALHGAPIYVRKEIVHNKYVVETLSDRGAIFVDETD 81

Query: 84  QVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIGH 143
           +VPEGA VVFSAHGV+P V AAA ER+LQTIDATCPLVTKVH EA RFA  DYDILLIGH
Sbjct: 82  EVPEGARVVFSAHGVSPAVVAAAEERSLQTIDATCPLVTKVHKEAVRFASEDYDILLIGH 141

Query: 144 EGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQR 203
           +GHEEV GTAGEAP+H+Q+V+  D  ++V +RD +KV+W+SQTTLSVDETME V RLR+R
Sbjct: 142 DGHEEVEGTAGEAPDHIQIVNSPDEVDKVVVRDPDKVIWISQTTLSVDETMETVRRLRER 201

Query: 204 FPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAAY 263
           FP LQDPPSDDICYATQNRQVAVK +APECD                   AL AGA+++Y
Sbjct: 202 FPTLQDPPSDDICYATQNRQVAVKKLAPECDLVIVVGSTNSSNSVRLVEVALNAGARSSY 261

Query: 264 LVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVFA 323
           LVD+A +ID+SW +          ASVPE+LV  VL  LAE GY  V+ V TA E L+F+
Sbjct: 262 LVDYAKEIDESWFEGVRTVGVTSGASVPEILVDEVLAYLAERGYGQVEEVRTATEDLMFS 321

Query: 324 LPREIR 329
           LPRE+R
Sbjct: 322 LPRELR 327


>tr|C7R1U2|C7R1U2_JONDD Tax_Id=471856 SubName:
           Full=Hydroxymethylbutenyl pyrophosphate reductase;
           EC=1.17.1.2;[Jonesia denitrificans]
          Length = 368

 Score =  398 bits (1022), Expect = e-109
 Identities = 200/309 (64%), Positives = 237/309 (76%)

Query: 21  TRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVE 80
           T +RVLLA PRGYCAGVDRAV  VE+ALE HG PVYVR EIVHN+ VV+TL   GA+FV 
Sbjct: 34  TGKRVLLAAPRGYCAGVDRAVIAVEKALEVHGAPVYVRKEIVHNKFVVETLTDRGAIFVN 93

Query: 81  ETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILL 140
           ETD+VPEGA VVFSAHGV+P V A+A +RNLQTIDATCPLVTKVH EA RFA +DYDILL
Sbjct: 94  ETDEVPEGARVVFSAHGVSPAVVASAQQRNLQTIDATCPLVTKVHKEAVRFASDDYDILL 153

Query: 141 IGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARL 200
           IGH+GHEEV GTAGEAP+H+Q+V+  D  ++V +RD +KVVW+SQTTLSVDETME V RL
Sbjct: 154 IGHDGHEEVEGTAGEAPDHIQVVNSPDEVDKVVVRDPDKVVWISQTTLSVDETMETVRRL 213

Query: 201 RQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQ 260
           R+RFP LQDPPSDDICYATQNRQVA+K +AP CD                   AL AGA+
Sbjct: 214 RERFPTLQDPPSDDICYATQNRQVAMKKLAPHCDLVLVVGSTNSSNSVRLTEVALDAGAR 273

Query: 261 AAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETL 320
           A+YL+D+A +ID++WL           ASVPE+LV+ VL+ LA+ GY  VQ V TA E L
Sbjct: 274 ASYLIDYAKEIDETWLDGVETVGLSSGASVPEILVQDVLKFLADRGYADVQEVRTATEDL 333

Query: 321 VFALPREIR 329
           +F+LPRE+R
Sbjct: 334 LFSLPRELR 342


>tr|C0U3C2|C0U3C2_9ACTO Tax_Id=526225 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Geodermatophilus obscurus DSM 43160]
          Length = 324

 Score =  397 bits (1021), Expect = e-109
 Identities = 204/311 (65%), Positives = 235/311 (75%)

Query: 22  RRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEE 81
           R RVLLA+PRGYCAGVDRAV  VERALE HG PVYVR +IVHN+HVV TL + GAVFV+E
Sbjct: 5   RGRVLLADPRGYCAGVDRAVVAVERALEIHGAPVYVRKQIVHNKHVVATLERRGAVFVDE 64

Query: 82  TDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLI 141
           TD+VPEG++VVFSAHGV+PTV+A AA R L+TIDATCPLVTKVH EA+RFAR+DYDILLI
Sbjct: 65  TDEVPEGSVVVFSAHGVSPTVHAEAAARQLRTIDATCPLVTKVHQEAKRFARDDYDILLI 124

Query: 142 GHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLR 201
           GH GHEEV GT+GEAP+H+QLVDG +    V +RD EKVVWLSQTTLSVDET+  V +L+
Sbjct: 125 GHRGHEEVEGTSGEAPDHIQLVDGAEDVADVQVRDPEKVVWLSQTTLSVDETLATVDQLK 184

Query: 202 QRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQA 261
            RFP LQ PPSDDICYATQNRQ AVK MA ECD                   AL AGA+A
Sbjct: 185 TRFPGLQSPPSDDICYATQNRQQAVKQMAAECDLVIVVGSTNSSNSVRLVEVALEAGARA 244

Query: 262 AYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLV 321
           +YLVD+A +ID +WL+          ASVPEVLV  VL+ LAE G+  V+ V  A E LV
Sbjct: 245 SYLVDFASEIDPAWLEGVGTVGVTSGASVPEVLVGEVLDWLAERGFPDVETVKAAEERLV 304

Query: 322 FALPREIRPAR 332
           FALP E+RP R
Sbjct: 305 FALPHELRPRR 315


>tr|A4F898|A4F898_SACEN Tax_Id=405948 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Saccharopolyspora erythraea]
          Length = 342

 Score =  393 bits (1010), Expect = e-107
 Identities = 204/324 (62%), Positives = 240/324 (74%), Gaps = 7/324 (2%)

Query: 6   DMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNR 65
           D   PGA+S+       +RVLLA+PRGYCAGVDRAV TVE+ALE +GPPVYVR EIVHN+
Sbjct: 12  DQDRPGAASN-------KRVLLAKPRGYCAGVDRAVITVEKALETYGPPVYVRKEIVHNK 64

Query: 66  HVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVH 125
           HVV+TL + G +FVEETD+VPEGA+VVFSAHGV+P V+  A  R+L+TIDATCPLVTKVH
Sbjct: 65  HVVETLRERGVIFVEETDEVPEGALVVFSAHGVSPAVHEEAERRSLRTIDATCPLVTKVH 124

Query: 126 NEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQ 185
            E  RFAR DYDILLIGHEGHEEV GT+GEAP+ VQLVD  +  ++VT+RD  KVVWLSQ
Sbjct: 125 KEVNRFAREDYDILLIGHEGHEEVEGTSGEAPDRVQLVDKPEDVDKVTVRDPSKVVWLSQ 184

Query: 186 TTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXX 245
           TTLSVDETME V +L+ RFP LQ PPSDDICYAT NRQVAVKAMA ECD           
Sbjct: 185 TTLSVDETMERVDQLKGRFPDLQAPPSDDICYATSNRQVAVKAMASECDLVLVVGSQNSS 244

Query: 246 XXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAES 305
                   AL AGA  ++L+D+A+ ID+SWL           ASVP+VLV  VL+ LAE 
Sbjct: 245 NSKRLVEVALQAGATDSHLIDYAEQIDESWLDGVTTVGVTSGASVPDVLVMQVLDFLAER 304

Query: 306 GYDMVQPVTTANETLVFALPREIR 329
           G+  V+ VTTANE + FALP E+R
Sbjct: 305 GWGDVEEVTTANEKIAFALPPELR 328


>tr|C5C0V8|C5C0V8_BEUC1 Tax_Id=471853 SubName:
           Full=Hydroxymethylbutenyl pyrophosphate reductase;
           EC=1.17.1.2;[Beutenbergia cavernae]
          Length = 331

 Score =  392 bits (1006), Expect = e-107
 Identities = 197/305 (64%), Positives = 231/305 (75%)

Query: 25  VLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETDQ 84
           +LLA PRGYCAGVDRAVE VERALE +G PVYVR EIVHN++VV+TL   GAVFVEETDQ
Sbjct: 1   MLLAAPRGYCAGVDRAVEAVERALEHYGAPVYVRKEIVHNKYVVETLTARGAVFVEETDQ 60

Query: 85  VPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIGHE 144
           VPEG  V+FSAHGV+P V+A AA R+LQTIDATCPLVTKVH EA RFAR D+DILLIGH+
Sbjct: 61  VPEGERVIFSAHGVSPAVHAQAAARSLQTIDATCPLVTKVHKEAVRFAREDFDILLIGHD 120

Query: 145 GHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQRF 204
           GHEEV GTAGEAP+HVQLV+G D  + V++RD E+VVWLSQTTLSVDETM+ V RLR+RF
Sbjct: 121 GHEEVEGTAGEAPDHVQLVNGPDAVDAVSVRDPERVVWLSQTTLSVDETMDTVRRLRERF 180

Query: 205 PKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAAYL 264
           P +QDPPSDDICYATQNRQVAVK +AP+CD                   AL AGA+++Y 
Sbjct: 181 PAMQDPPSDDICYATQNRQVAVKKLAPDCDLVIVVGSANSSNSVRLVEVALDAGARSSYR 240

Query: 265 VDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVFAL 324
           +D A ++   W            ASVPE+LVR VL+ LA  GY  V+ V TA E L+F+L
Sbjct: 241 IDQASELRDEWFDGVTTVGLTSGASVPEILVRDVLDALATRGYGEVEEVRTATEDLMFSL 300

Query: 325 PREIR 329
           PRE+R
Sbjct: 301 PRELR 305


>tr|C9ND23|C9ND23_9ACTO Tax_Id=591167 SubName:
           Full=Hydroxymethylbutenyl pyrophosphate reductase;
           EC=1.17.1.2;[Streptomyces flavogriseus ATCC 33331]
          Length = 346

 Score =  390 bits (1002), Expect = e-106
 Identities = 198/318 (62%), Positives = 236/318 (74%)

Query: 12  ASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTL 71
           AS   +     RRVLLA PRGYCAGVDRAV  VE+ALE++G P+YVRHEIVHN++VV TL
Sbjct: 16  ASGDASRSSGDRRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVRHEIVHNKYVVQTL 75

Query: 72  AKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRF 131
            K GA+FV+ T +VPEG+IV+FSAHGVAPTV+A AAER L TIDATCPLVTKVH EA R+
Sbjct: 76  EKKGAIFVDVTAEVPEGSIVMFSAHGVAPTVHAEAAERKLATIDATCPLVTKVHKEAVRY 135

Query: 132 ARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVD 191
           A+ DYDILLIGHEGHEEV+GT+GEAP+H+ LVDG D    V +RDE KVVWLSQTTLSVD
Sbjct: 136 AKEDYDILLIGHEGHEEVIGTSGEAPDHITLVDGPDDVANVEVRDESKVVWLSQTTLSVD 195

Query: 192 ETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXX 251
           ETME V  L+ +FP L  PPSDDICYATQNRQVAVK +A + D                 
Sbjct: 196 ETMETVGALKNKFPNLLSPPSDDICYATQNRQVAVKKLAEDADLVIVVGSKNSSNSIRMV 255

Query: 252 XXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQ 311
             AL AGA AA+LVD+A +ID++WL+          ASVP+VLV GVLE L E GY  V+
Sbjct: 256 EVALDAGAPAAHLVDFASEIDEAWLEGVTTVGLTSGASVPDVLVDGVLEWLGERGYADVE 315

Query: 312 PVTTANETLVFALPREIR 329
            V TA+E++ F+LP+E+R
Sbjct: 316 TVKTADESITFSLPKELR 333


>tr|C0XPW6|C0XPW6_9CORY Tax_Id=525263 (ispH)SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Corynebacterium lipophiloflavum DSM 44291]
          Length = 317

 Score =  390 bits (1001), Expect = e-106
 Identities = 196/311 (63%), Positives = 239/311 (76%), Gaps = 1/311 (0%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           + VLLA PRGYCAGVDRAVETVE+ALEK+G PVYVR +IVHN++VV+TL + G +FVEET
Sbjct: 6   KNVLLAAPRGYCAGVDRAVETVEKALEKYGAPVYVRKQIVHNKYVVETLEERGVIFVEET 65

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           D+VPEGA +VFSAHG++P V  +A +RNL T+DATCPLVTKVHNEA+RFAR+ Y ILL+G
Sbjct: 66  DEVPEGAHLVFSAHGISPAVRESAIQRNLLTLDATCPLVTKVHNEAKRFARDGYQILLVG 125

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDG-AERVTIRDEEKVVWLSQTTLSVDETMEIVARLR 201
           HEGHEEV GTAGEAPE   LVDGLDG A       ++K+VWLSQTTLSVDETMEIV +L 
Sbjct: 126 HEGHEEVEGTAGEAPEVTHLVDGLDGVASLPDFGPDQKLVWLSQTTLSVDETMEIVNKLF 185

Query: 202 QRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQA 261
           +RFP L++PPSDDICYATQNRQVAVKA+AP+CD                   AL AGA+A
Sbjct: 186 ERFPHLENPPSDDICYATQNRQVAVKAIAPKCDLVIVVGSQNSSNSKRLVEVALEAGAKA 245

Query: 262 AYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLV 321
           +YLVD+A +ID+SWL+          ASVPE+LVR VLE L + GY  ++  TT  ET+ 
Sbjct: 246 SYLVDFAREIDESWLEGVMTVGVTSGASVPEILVREVLEYLDDRGYSDIEQATTTTETIT 305

Query: 322 FALPREIRPAR 332
           F+LPR++RP+R
Sbjct: 306 FSLPRDLRPSR 316


>tr|C0E7L6|C0E7L6_9CORY Tax_Id=566549 SubName: Full=Putative
           uncharacterized protein;[Corynebacterium matruchotii
           ATCC 33806]
          Length = 343

 Score =  389 bits (998), Expect = e-106
 Identities = 200/333 (60%), Positives = 242/333 (72%), Gaps = 2/333 (0%)

Query: 2   VPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEI 61
           V   D+    A+ + A +   ++VL+A PRGYCAGVDRAVETVERALEK+G PVYVR EI
Sbjct: 8   VSATDVDATDAADAPATITKTKKVLVAAPRGYCAGVDRAVETVERALEKYGAPVYVRKEI 67

Query: 62  VHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLV 121
           VHNR+VV+TL + GA+FV+ETD+VPEGA V+FSAHGV+P V+A AA+ +L+T+DATCPLV
Sbjct: 68  VHNRYVVETLTERGAIFVQETDEVPEGAHVIFSAHGVSPAVHAEAAKLSLKTLDATCPLV 127

Query: 122 TKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVT--IRDEEK 179
           TKVHNEA+RFA++ Y ILL+GHEGHEEV GTAGEAPE   LVDG+ G  ++   + + E 
Sbjct: 128 TKVHNEAKRFAKHGYHILLVGHEGHEEVEGTAGEAPEVTHLVDGVAGVAKLPEFLHEVEN 187

Query: 180 VVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXX 239
           +VWLSQTTLSVDETMEIV  L  RFP+LQDPPSDDICYATQNRQ AVK ++   D     
Sbjct: 188 LVWLSQTTLSVDETMEIVTELHNRFPQLQDPPSDDICYATQNRQGAVKVISENADLVIVV 247

Query: 240 XXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVL 299
                         AL AGA+ +YLVD+A  ID+SWL           ASVPE+LV GVL
Sbjct: 248 GSRNSSNSKRLVEVALQAGAKRSYLVDYAHQIDESWLDGVSTIGVTSGASVPEILVNGVL 307

Query: 300 ERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           E LAE G+  V+ VTT  E  VFALPRE+RP R
Sbjct: 308 EWLAERGFTSVEEVTTVTEKTVFALPRELRPPR 340


>sp|B1W2D7|ISPH_STRGG Tax_Id=455632 (ispH)RecName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Streptomyces griseus subsp. griseus]
          Length = 329

 Score =  388 bits (996), Expect = e-106
 Identities = 194/307 (63%), Positives = 235/307 (76%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           RRVLLA PRGYCAGVDRAV  VE+ALE++G P+YVRHEIVHN++VV TL K GA+FV+ T
Sbjct: 10  RRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVRHEIVHNKYVVQTLEKKGAIFVDVT 69

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
            +VPEG+IV+FSAHGVAPTV+A AAER L TIDATCPLVTKVH EA R+A++DYDILLIG
Sbjct: 70  AEVPEGSIVMFSAHGVAPTVHAEAAERKLATIDATCPLVTKVHKEAVRYAKDDYDILLIG 129

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           HEGHEEV+GT+GEAP+H+QLVDG +    V +RDE KVVWLSQTTLSVDETME V  L+ 
Sbjct: 130 HEGHEEVIGTSGEAPDHIQLVDGPEDVANVEVRDESKVVWLSQTTLSVDETMETVDALKS 189

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           +FP L  PPSDDICYATQNRQ+AVK +A + +                   AL AGA AA
Sbjct: 190 KFPNLLSPPSDDICYATQNRQIAVKKLAEDAELVIVVGSKNSSNSIRMVEVALDAGAPAA 249

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           +LVD+A +ID++WL+          ASVP+VLV GVLE L E GY  V+ V TA+E++ F
Sbjct: 250 HLVDFASEIDEAWLEGVTTVGLTSGASVPDVLVDGVLEWLGERGYADVETVKTADESITF 309

Query: 323 ALPREIR 329
           +LP+E+R
Sbjct: 310 SLPKELR 316


>tr|C5VBB7|C5VBB7_9CORY Tax_Id=553207 (ispH)SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Corynebacterium matruchotii ATCC 14266]
          Length = 343

 Score =  388 bits (996), Expect = e-106
 Identities = 200/333 (60%), Positives = 242/333 (72%), Gaps = 2/333 (0%)

Query: 2   VPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEI 61
           V   D+    A+ + A +   ++VL+A PRGYCAGVDRAVETVERALEK+G PVYVR EI
Sbjct: 8   VSATDVDATDAADAPATMTKTKKVLVAAPRGYCAGVDRAVETVERALEKYGAPVYVRKEI 67

Query: 62  VHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLV 121
           VHNR+VV+TL + GA+FV+ETD+VPEGA V+FSAHGV+P V+A AA+ +L+T+DATCPLV
Sbjct: 68  VHNRYVVETLTERGAIFVQETDEVPEGAHVIFSAHGVSPAVHAEAAKLSLKTLDATCPLV 127

Query: 122 TKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVT--IRDEEK 179
           TKVHNEA+RFA++ Y ILL+GHEGHEEV GTAGEAPE   LVDG+ G  ++   + + E 
Sbjct: 128 TKVHNEAKRFAKHGYHILLVGHEGHEEVEGTAGEAPEVTHLVDGVAGVAKLPEFLHEVEN 187

Query: 180 VVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXX 239
           +VWLSQTTLSVDETMEIV  L  RFP+LQDPPSDDICYATQNRQ AVK ++   D     
Sbjct: 188 LVWLSQTTLSVDETMEIVTELHNRFPQLQDPPSDDICYATQNRQGAVKVISENADLVIVV 247

Query: 240 XXXXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVL 299
                         AL AGA+ +YLVD+A  ID+SWL           ASVPE+LV GVL
Sbjct: 248 GSRNSSNSKRLVEVALQAGAKRSYLVDYAHQIDESWLDGVSTIGVTSGASVPEILVNGVL 307

Query: 300 ERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
           E LAE G+  V+ VTT  E  VFALPRE+RP R
Sbjct: 308 EWLAERGFTSVEEVTTVTEKTVFALPRELRPPR 340


>tr|C1RMZ8|C1RMZ8_9CELL Tax_Id=446466 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Cellulomonas flavigena DSM 20109]
          Length = 351

 Score =  387 bits (995), Expect = e-106
 Identities = 201/308 (65%), Positives = 229/308 (74%)

Query: 22  RRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEE 81
           R+RVLLA PRGYCAGVDRAV  VE+ALE +G PVYVR EIVHNRHVVDTLA  GAVFV+E
Sbjct: 18  RKRVLLAAPRGYCAGVDRAVIAVEKALEHYGAPVYVRKEIVHNRHVVDTLAARGAVFVDE 77

Query: 82  TDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLI 141
           TD+VPEGA VVFSAHGV+P V A+AA RNLQTIDATCPLVTKVH EA RFA +D+DILLI
Sbjct: 78  TDEVPEGARVVFSAHGVSPAVKASAAARNLQTIDATCPLVTKVHKEAVRFAADDFDILLI 137

Query: 142 GHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLR 201
           GH GHEEV GT G APEH+Q+V+  D A+ V +RD E+V+W+SQTTLSVDETME V RLR
Sbjct: 138 GHTGHEEVEGTQGHAPEHIQVVNSPDDADHVEVRDPERVMWISQTTLSVDETMETVRRLR 197

Query: 202 QRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQA 261
            +FP LQDPPSDDICYATQNRQVAVK +AP CD                   AL AGA  
Sbjct: 198 VKFPHLQDPPSDDICYATQNRQVAVKKLAPSCDVVITVGSANSSNSVRLVEVALDAGAGV 257

Query: 262 AYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLV 321
           +Y VD A +ID +WL           ASVPE+LV  VL  LAE G+  V+ V TA E L+
Sbjct: 258 SYRVDKAAEIDPAWLVGATTVGVTSGASVPEILVSDVLAFLAEHGFGEVEEVRTATEDLM 317

Query: 322 FALPREIR 329
           F+LPRE+R
Sbjct: 318 FSLPRELR 325


>tr|D1A8I1|D1A8I1_THECU Tax_Id=471852 SubName:
           Full=Hydroxymethylbutenyl pyrophosphate reductase;
           EC=1.17.1.2;[Thermomonospora curvata DSM 43183]
          Length = 320

 Score =  387 bits (993), Expect = e-105
 Identities = 194/307 (63%), Positives = 232/307 (75%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           RRVLLA+PRGYCAGVDRAV TVE ALEK+G P+YVR +IVHN HVV TL + GA+FV+ET
Sbjct: 7   RRVLLAKPRGYCAGVDRAVRTVEIALEKYGAPIYVRKQIVHNVHVVKTLEERGAIFVDET 66

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           ++VPEGAIV+FSAHGVAP V+  A  RNL+TIDATCPLVTKVH EA RFA +DYDILLIG
Sbjct: 67  EEVPEGAIVIFSAHGVAPAVHEEARARNLRTIDATCPLVTKVHKEAVRFAADDYDILLIG 126

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           HEGHEEV+GT+GEAP+H++LVDG D    V +RD +KV WLSQTTLSVDETM  VA LR+
Sbjct: 127 HEGHEEVIGTSGEAPDHIRLVDGPDDVANVQVRDPDKVAWLSQTTLSVDETMATVAALRE 186

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           RFP L DPPSDDICYATQNRQ AVK +A + +                   A   GA+AA
Sbjct: 187 RFPNLVDPPSDDICYATQNRQTAVKQIAAQAELVIVVGSQNSSNSVRLVEVAKEYGAKAA 246

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           +LVD+AD ID +WL+          ASVPE+LVRGVL+ LAE GYD V+ + +  E++ F
Sbjct: 247 HLVDYADQIDPAWLEGVSTVGVTSGASVPEILVRGVLDWLAERGYDRVEEIESVPESMRF 306

Query: 323 ALPREIR 329
           ALP+E+R
Sbjct: 307 ALPKELR 313


>tr|D0WPZ0|D0WPZ0_9ACTO Tax_Id=649743 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate
           reductase;[Actinomyces sp. oral taxon 848 str. F0332]
          Length = 385

 Score =  386 bits (992), Expect = e-105
 Identities = 195/328 (59%), Positives = 243/328 (74%), Gaps = 5/328 (1%)

Query: 7   MGIPGASSSVAHVPT-----RRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEI 61
           + + GAS+    +P+      RR+L+A PRGYCAGVDRAV+ VE+ALE +G PVYVR EI
Sbjct: 24  VSLAGASAFPDRIPSVPGRDGRRILIATPRGYCAGVDRAVDAVEKALELYGAPVYVRKEI 83

Query: 62  VHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLV 121
           VHN++VV+TL++ GA+FV ET++VPEGA VVFSAHGV+P V+A AA R+LQTIDATCPLV
Sbjct: 84  VHNKYVVETLSRRGAIFVSETEEVPEGARVVFSAHGVSPAVHAEAAARSLQTIDATCPLV 143

Query: 122 TKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVV 181
           TKVH +A RFA++DYDILLIGH GHEEV GT GEAPEH+Q+V+G +  + + +RD +KVV
Sbjct: 144 TKVHKQAVRFAKDDYDILLIGHTGHEEVEGTQGEAPEHIQVVNGPEEVDGIEVRDPDKVV 203

Query: 182 WLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXX 241
           W+SQTTLSVDET++ V RLR+RFP L DPPSDDICYATQNRQ AVKAMAPECD       
Sbjct: 204 WISQTTLSVDETLKTVRRLRERFPNLVDPPSDDICYATQNRQGAVKAMAPECDAVIVVGS 263

Query: 242 XXXXXXXXXXXXALGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLER 301
                       AL AGA  AY VD A+++   WL+          ASVPE+LVR V+ER
Sbjct: 264 ANSSNSVRLVEVALEAGAGKAYRVDRAEEVRDEWLEGVQTVGLTSGASVPEILVRDVVER 323

Query: 302 LAESGYDMVQPVTTANETLVFALPREIR 329
           LAE G+  V PV TA+E + F+LP+ +R
Sbjct: 324 LAEIGFTQVDPVQTASEDIRFSLPKNLR 351


>tr|C4RPS1|C4RPS1_9ACTO Tax_Id=219305 SubName:
           Full=Hydroxymethylbutenyl pyrophosphate
           reductase;[Micromonospora sp. ATCC 39149]
          Length = 329

 Score =  385 bits (988), Expect = e-105
 Identities = 194/309 (62%), Positives = 228/309 (73%)

Query: 21  TRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVE 80
           T +RVLLA+PRGYCAGVDRAV+TVE AL  +G P+YVR +IVHN+HVV TL   GAVFVE
Sbjct: 10  TGKRVLLAKPRGYCAGVDRAVQTVEEALRLYGAPIYVRKQIVHNKHVVRTLEAKGAVFVE 69

Query: 81  ETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILL 140
           E ++VPEGA V+FSAHGVAP VY  A  R+L+ IDATCPLVTKVH EA+RFA  DYDILL
Sbjct: 70  ENEEVPEGATVIFSAHGVAPEVYEQARARSLKAIDATCPLVTKVHQEAKRFAAEDYDILL 129

Query: 141 IGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARL 200
           IGHEGHEEV+GTAGEAP H+QLVDG D A++VT+RD  KVVWLSQTTLSVDET+E VARL
Sbjct: 130 IGHEGHEEVIGTAGEAPAHIQLVDGPDDADKVTVRDPSKVVWLSQTTLSVDETLETVARL 189

Query: 201 RQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQ 260
           + R P LQ PPSDDICYAT NRQ  VK +APECD                   AL AGA+
Sbjct: 190 KSRLPLLQSPPSDDICYATSNRQHVVKEIAPECDVVLVVGSRNSSNSVRLVEVALDAGAR 249

Query: 261 AAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETL 320
           A +LVD+A +ID +WL+          ASVP+ LV+ VL  LA  G+  V  V TANE L
Sbjct: 250 AGHLVDFAHEIDDAWLEGAGTVGLTSGASVPDELVQDVLAHLAARGFTDVDEVVTANERL 309

Query: 321 VFALPREIR 329
            F+LP+E++
Sbjct: 310 TFSLPQELK 318


>tr|C7NKU3|C7NKU3_KYTSD Tax_Id=478801 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Kytococcus sedentarius]
          Length = 339

 Score =  384 bits (986), Expect = e-105
 Identities = 199/307 (64%), Positives = 227/307 (73%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           +RVLLA PRGYCAGVDRAV TVE+ALE +G PVYVR EIVHN+HVVDTL + GAVFVEET
Sbjct: 10  KRVLLAAPRGYCAGVDRAVVTVEKALELYGAPVYVRKEIVHNKHVVDTLRRRGAVFVEET 69

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           D+VPEGA V+FSAHGVAP V+  A  R+L++IDATCPLVTKVH EA RFA +DYDILLIG
Sbjct: 70  DEVPEGATVIFSAHGVAPIVHEEAKARSLKSIDATCPLVTKVHREAVRFADDDYDILLIG 129

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           HEGHEEVVGTAGEAPEHV LVDG +G + V +RD EKVVWLSQTTLSVDETME V  LR+
Sbjct: 130 HEGHEEVVGTAGEAPEHVILVDGPEGVKDVEVRDPEKVVWLSQTTLSVDETMETVRLLRE 189

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           +FP LQDPPSDDICYATQNRQ+AVK MAPE D                   AL  GA+  
Sbjct: 190 KFPSLQDPPSDDICYATQNRQLAVKQMAPELDLMLVVGSRNSSNSVRLVEVALEHGARDG 249

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           YLVD+A ++   W +          ASVPE+LVR VL+ LA  GY  V   T A E ++F
Sbjct: 250 YLVDYAAELQDEWFEGVETVGVSSGASVPEILVRDVLDDLAARGYLDVDVFTAAEEKMLF 309

Query: 323 ALPREIR 329
            LP E+R
Sbjct: 310 QLPGELR 316


>tr|A0JYU2|A0JYU2_ARTS2 Tax_Id=290399 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Arthrobacter sp.]
          Length = 359

 Score =  384 bits (986), Expect = e-105
 Identities = 188/315 (59%), Positives = 239/315 (75%)

Query: 15  SVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKA 74
           + A VP  ++VLLA PRGYCAGVDRAV  VE+ALE +GPPVYVR +IVHN HVV +L + 
Sbjct: 25  AAAPVPGPKKVLLAAPRGYCAGVDRAVIAVEKALEHYGPPVYVRKQIVHNVHVVSSLEEK 84

Query: 75  GAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARN 134
           GA+FV+ETD+VPEGA+V+FSAHGV+P V  +A +R L+TIDATCPLVTKVH EA RFA++
Sbjct: 85  GAIFVDETDEVPEGALVIFSAHGVSPAVVQSAEDRGLRTIDATCPLVTKVHREAVRFAKD 144

Query: 135 DYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETM 194
           D+DILLIGH+GHEEV GTAGEAPEH+Q+++G    ++VT+RD EKV+WLSQTTLSVDETM
Sbjct: 145 DFDILLIGHDGHEEVEGTAGEAPEHIQIINGPHEVDKVTVRDPEKVIWLSQTTLSVDETM 204

Query: 195 EIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXA 254
           E V  L++RFP LQDPPSDDICYAT NRQVA+K ++P+ D                   A
Sbjct: 205 ETVRLLKERFPTLQDPPSDDICYATTNRQVAIKKISPQADLVIVVGSANSSNSVRLVEVA 264

Query: 255 LGAGAQAAYLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVT 314
           L  GA+A+Y VD+A+++D++W +          ASVPEVLV+ VL  LA+ GY  V+ V 
Sbjct: 265 LEYGAKASYRVDFANEVDEAWFEGVATVGVTSGASVPEVLVKDVLRLLADYGYGTVEEVV 324

Query: 315 TANETLVFALPREIR 329
           TA E L+F+LP+E+R
Sbjct: 325 TAEEDLLFSLPKELR 339


>tr|C4DTW7|C4DTW7_9ACTO Tax_Id=446470 SubName:
           Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
           EC=1.17.1.2;[Stackebrandtia nassauensis DSM 44728]
          Length = 325

 Score =  383 bits (984), Expect = e-104
 Identities = 194/306 (63%), Positives = 230/306 (75%)

Query: 23  RRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 82
           +RVLLA+PRGYCAGVDRAVETVE+ALE +GPPVYVR +IVHN+HVV TL +AGA+FVEE 
Sbjct: 6   KRVLLAKPRGYCAGVDRAVETVEKALELYGPPVYVRKQIVHNKHVVATLEEAGAIFVEEN 65

Query: 83  DQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIG 142
           D+VP G+IVVFSAHGVAP V+  A +R+L+ IDATCPLVTKVH+EARRFA  DYDILLIG
Sbjct: 66  DEVPPGSIVVFSAHGVAPEVHEQAKQRDLKAIDATCPLVTKVHSEARRFAAQDYDILLIG 125

Query: 143 HEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQ 202
           H+GHEEV+GT GEAPE++ LVDG +  + V +RDE KVVWLSQTTLSVDETM+ V  LRQ
Sbjct: 126 HDGHEEVIGTTGEAPENITLVDGPEDVKNVKVRDENKVVWLSQTTLSVDETMDTVDGLRQ 185

Query: 203 RFPKLQDPPSDDICYATQNRQVAVKAMAPECDXXXXXXXXXXXXXXXXXXXALGAGAQAA 262
           RFP LQ PPSDDICYATQNRQ  VK +A +CD                   AL AG++A 
Sbjct: 186 RFPLLQSPPSDDICYATQNRQQVVKEIADDCDVMLVVGSTNSSNSVRLVEVALQAGSRAG 245

Query: 263 YLVDWADDIDQSWLQXXXXXXXXXXASVPEVLVRGVLERLAESGYDMVQPVTTANETLVF 322
           YLVD+A +I +SWL+          ASVP+ LV GVLE LAE G+  V  V +  E L F
Sbjct: 246 YLVDYAHEIQESWLEGATTVGVTSGASVPDDLVTGVLEFLAERGFTDVAEVESVKEKLTF 305

Query: 323 ALPREI 328
           +LPRE+
Sbjct: 306 SLPREL 311


  Database: Amellifera_nr
    Posted date:  Feb 5, 2010  5:10 AM
  Number of letters in database: 3,846,993,858
  Number of sequences in database:  11,275,203
  
Lambda     K      H
   0.318    0.133    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11275203
Number of Hits to DB: 2,224,799,550
Number of extensions: 83050459
Number of successful extensions: 218995
Number of sequences better than 10.0: 1630
Number of HSP's gapped: 217303
Number of HSP's successfully gapped: 1638
Length of query: 332
Length of database: 3,846,993,858
Length adjustment: 138
Effective length of query: 194
Effective length of database: 2,291,015,844
Effective search space: 444457073736
Effective search space used: 444457073736
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 80 (35.4 bits)