BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_4784 (304 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HG76|B2HG76_MYCMM Tax_Id=216594 SubName: Full=Dehydrogenase... 576 e-162 tr|O53855|O53855_MYCTU Tax_Id=1773 SubName: Full=Dehydrogenase E... 249 2e-64 tr|C6DWQ2|C6DWQ2_MYCTK Tax_Id=478434 SubName: Full=Dehydrogenase... 249 2e-64 tr|C1ALH7|C1ALH7_MYCBT Tax_Id=561275 SubName: Full=Putative dehy... 249 2e-64 tr|A5U0N1|A5U0N1_MYCTA Tax_Id=419947 SubName: Full=Dehydrogenase... 249 2e-64 tr|A1KGX5|A1KGX5_MYCBP Tax_Id=410289 SubName: Full=Probable dehy... 249 2e-64 tr|A5WKL4|A5WKL4_MYCTF Tax_Id=336982 SubName: Full=Hypothetical ... 249 2e-64 tr|A4KFF3|A4KFF3_MYCTU Tax_Id=395095 SubName: Full=Hypothetical ... 249 2e-64 tr|A2VGE1|A2VGE1_MYCTU Tax_Id=348776 SubName: Full=Putative unch... 249 2e-64 tr|Q7U150|Q7U150_MYCBO Tax_Id=1765 SubName: Full=PROBABLE DEHYDR... 249 3e-64 tr|A0QB51|A0QB51_MYCA1 Tax_Id=243243 SubName: Full=Dehydrogenase... 169 3e-40 tr|Q742Z7|Q742Z7_MYCPA Tax_Id=1770 SubName: Full=Putative unchar... 169 5e-40 tr|A5V557|A5V557_SPHWW Tax_Id=392499 SubName: Full=Pyruvate dehy... 121 1e-25 tr|C8XE57|C8XE57_NAKMY Tax_Id=479431 SubName: Full=Pyruvate dehy... 109 3e-22 tr|B9LC81|B9LC81_CHLSY Tax_Id=480224 SubName: Full=Pyruvate dehy... 105 7e-21 tr|A9W9S7|A9W9S7_CHLAA Tax_Id=324602 SubName: Full=Pyruvate dehy... 105 7e-21 tr|B5HWC3|B5HWC3_9ACTO Tax_Id=463191 SubName: Full=Pyruvate dehy... 102 6e-20 tr|Q28MR4|Q28MR4_JANSC Tax_Id=290400 SubName: Full=Dehydrogenase... 101 9e-20 tr|A4AFX0|A4AFX0_9ACTN Tax_Id=312284 SubName: Full=Acetoin dehyd... 100 3e-19 tr|C5NUE3|C5NUE3_9BACL Tax_Id=546270 (acoA)SubName: Full=TPP-dep... 100 4e-19 tr|Q46RB0|Q46RB0_RALEJ Tax_Id=264198 SubName: Full=Pyruvate dehy... 99 5e-19 tr|D1C9N9|D1C9N9_9CHLR Tax_Id=479434 SubName: Full=Pyruvate dehy... 99 8e-19 tr|A9HDU8|A9HDU8_9RHOB Tax_Id=391595 SubName: Full=Acetoin dehyd... 98 1e-18 tr|Q1ARM0|Q1ARM0_RUBXD Tax_Id=266117 SubName: Full=Pyruvate dehy... 97 2e-18 tr|Q74AD3|Q74AD3_GEOSL Tax_Id=35554 SubName: Full=Dehydrogenase ... 97 3e-18 sp|O31404|ACOA_BACSU Tax_Id=1423 (acoA)RecName: Full=Acetoin:2,6... 96 4e-18 tr|A1SN84|A1SN84_NOCSJ Tax_Id=196162 SubName: Full=Pyruvate dehy... 96 4e-18 tr|Q8YTK9|Q8YTK9_ANASP Tax_Id=103690 SubName: Full=Pyruvate dehy... 96 7e-18 tr|Q8RD61|Q8RD61_THETN Tax_Id=119072 (AcoA)SubName: Full=Thiamin... 96 7e-18 tr|Q3M561|Q3M561_ANAVT Tax_Id=240292 SubName: Full=Dehydrogenase... 96 7e-18 tr|A3U0V2|A3U0V2_9RHOB Tax_Id=252305 SubName: Full=Acetoin dehyd... 96 7e-18 tr|Q2JWW4|Q2JWW4_SYNJA Tax_Id=321327 SubName: Full=Dehydrogenase... 95 9e-18 tr|C2W8P8|C2W8P8_BACCE Tax_Id=526986 SubName: Full=Pyruvate dehy... 94 2e-17 tr|C1A6D2|C1A6D2_GEMAT Tax_Id=379066 (pdhA)SubName: Full=Pyruvat... 94 2e-17 tr|C5PMC1|C5PMC1_9SPHI Tax_Id=525373 (pdhA)SubName: Full=Pyruvat... 94 2e-17 tr|C2G077|C2G077_9SPHI Tax_Id=525372 (pdhA)SubName: Full=Pyruvat... 94 2e-17 tr|A4YG22|A4YG22_METS5 Tax_Id=399549 SubName: Full=Pyruvate dehy... 94 2e-17 tr|Q2JPJ0|Q2JPJ0_SYNJB Tax_Id=321332 SubName: Full=Dehydrogenase... 94 3e-17 tr|A0ZHY4|A0ZHY4_NODSP Tax_Id=313624 SubName: Full=Dehydrogenase... 93 3e-17 tr|Q0MX87|Q0MX87_9BACT Tax_Id=397422 SubName: Full=Acetoin dehyd... 93 4e-17 tr|B7R8L3|B7R8L3_9THEO Tax_Id=391606 (pdhA_2)SubName: Full=Pyruv... 93 4e-17 tr|A4AIF8|A4AIF8_9ACTN Tax_Id=312284 SubName: Full=Acetoin dehyd... 93 4e-17 tr|B9LFA5|B9LFA5_CHLSY Tax_Id=480224 SubName: Full=Pyruvate dehy... 92 8e-17 tr|B0SQK8|B0SQK8_LEPBP Tax_Id=456481 (acoA)SubName: Full=Pyruvat... 92 8e-17 tr|A9WB62|A9WB62_CHLAA Tax_Id=324602 SubName: Full=Pyruvate dehy... 92 8e-17 tr|C4WR55|C4WR55_9RHIZ Tax_Id=641118 SubName: Full=Pyruvate dehy... 92 8e-17 tr|A8TJR3|A8TJR3_9PROT Tax_Id=331869 SubName: Full=Thiamine pyro... 92 8e-17 tr|Q5N030|Q5N030_SYNP6 Tax_Id=269084 (pdhA)SubName: Full=Pyruvat... 92 1e-16 tr|Q31LU5|Q31LU5_SYNE7 Tax_Id=1140 SubName: Full=Pyruvate dehydr... 92 1e-16 tr|Q0APT0|Q0APT0_MARMM Tax_Id=394221 SubName: Full=Dehydrogenase... 92 1e-16 >tr|B2HG76|B2HG76_MYCMM Tax_Id=216594 SubName: Full=Dehydrogenase;[Mycobacterium marinum] Length = 304 Score = 576 bits (1485), Expect = e-162 Identities = 289/304 (95%), Positives = 289/304 (95%) Query: 1 MTHASARPAALLPDHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATA 60 MTHASARPAALLPDHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATA Sbjct: 1 MTHASARPAALLPDHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATA 60 Query: 61 ALTEGDLVLASRRAHALHVGVDLPLGPMIAELIGQDSTCDHADQLNSPERSGAADQCPLL 120 ALTEGDLVLASRRAHALHVGVDLPLGPMIAELIGQDSTCDHADQLNSPERSGAADQCPLL Sbjct: 61 ALTEGDLVLASRRAHALHVGVDLPLGPMIAELIGQDSTCDHADQLNSPERSGAADQCPLL 120 Query: 121 AVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXR 180 AVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLP R Sbjct: 121 AVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPVVIVVESVPGVGVAGR 180 Query: 181 LRGAPGHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPS 240 LRGAPGHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPS Sbjct: 181 LRGAPGHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPS 240 Query: 241 FDGDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKSGTCPGH 300 FDGDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKSGTCPGH Sbjct: 241 FDGDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKSGTCPGH 300 Query: 301 DGRS 304 DGRS Sbjct: 301 DGRS 304 >tr|O53855|O53855_MYCTU Tax_Id=1773 SubName: Full=Dehydrogenase E1 component; SubName: Full=PROBABLE DEHYDROGENASE; EC=1.-.-.-;[Mycobacterium tuberculosis] Length = 334 Score = 249 bits (637), Expect = 2e-64 Identities = 151/326 (46%), Positives = 195/326 (59%), Gaps = 33/326 (10%) Query: 1 MTHASARPAALLPDHLE-MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGAT 59 MT S AA + D LE +YRRMWVLRLLDMALE++R +GL+ P+ GQEAVS+GA Sbjct: 1 MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAA 60 Query: 60 AALTEGDLVLASRRAHALHVGVDLPLGPMIAELI--------GQDSTCDHAD-QLNSPER 110 AAL EGD+++ + R HA HVG D PLGP+IA+++ G D AD + P Sbjct: 61 AALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAA 120 Query: 111 SGAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXX 170 Q PLLA+GHAY+ WL ++ RVTLC+T DV++ AF +AA++A +W LP Sbjct: 121 IRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLP------ 174 Query: 171 XXXXXXXXXRLRGAPG-------HGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQR 218 +RGA H +R +P V+VDG+DV+AVR CVA AV R Sbjct: 175 ---VVILVENIRGALSVHLDRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVR 231 Query: 219 ARAGAGPTVVRAITYRSSDFPSFD--GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCD 276 ARAG GPT+V+AITYR++DF D G D A +E FLDPL+F RL A G +L + Sbjct: 232 ARAGGGPTLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDE 291 Query: 277 VERTARKLVADAVALAKSGTCPGHDG 302 ER A + VADAVA AK+ P G Sbjct: 292 QERAACQQVADAVAFAKARARPNGGG 317 >tr|C6DWQ2|C6DWQ2_MYCTK Tax_Id=478434 SubName: Full=Dehydrogenase;[Mycobacterium tuberculosis] Length = 334 Score = 249 bits (637), Expect = 2e-64 Identities = 151/326 (46%), Positives = 195/326 (59%), Gaps = 33/326 (10%) Query: 1 MTHASARPAALLPDHLE-MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGAT 59 MT S AA + D LE +YRRMWVLRLLDMALE++R +GL+ P+ GQEAVS+GA Sbjct: 1 MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAA 60 Query: 60 AALTEGDLVLASRRAHALHVGVDLPLGPMIAELI--------GQDSTCDHAD-QLNSPER 110 AAL EGD+++ + R HA HVG D PLGP+IA+++ G D AD + P Sbjct: 61 AALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAA 120 Query: 111 SGAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXX 170 Q PLLA+GHAY+ WL ++ RVTLC+T DV++ AF +AA++A +W LP Sbjct: 121 IRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLP------ 174 Query: 171 XXXXXXXXXRLRGAPG-------HGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQR 218 +RGA H +R +P V+VDG+DV+AVR CVA AV R Sbjct: 175 ---VVILVENIRGALSVHLDRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVR 231 Query: 219 ARAGAGPTVVRAITYRSSDFPSFD--GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCD 276 ARAG GPT+V+AITYR++DF D G D A +E FLDPL+F RL A G +L + Sbjct: 232 ARAGGGPTLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDE 291 Query: 277 VERTARKLVADAVALAKSGTCPGHDG 302 ER A + VADAVA AK+ P G Sbjct: 292 QERAACQQVADAVAFAKARARPNGGG 317 >tr|C1ALH7|C1ALH7_MYCBT Tax_Id=561275 SubName: Full=Putative dehydrogenase;[Mycobacterium bovis] Length = 334 Score = 249 bits (637), Expect = 2e-64 Identities = 149/319 (46%), Positives = 192/319 (60%), Gaps = 19/319 (5%) Query: 1 MTHASARPAALLPDHLE-MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGAT 59 MT S AA + D LE +YRRMWVLRLLDMALE++R +GL+ P+ GQEAVS+GA Sbjct: 1 MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAA 60 Query: 60 AALTEGDLVLASRRAHALHVGVDLPLGPMIAELI--------GQDSTCDHAD-QLNSPER 110 AAL EGD+++ + R HA HVG D PLGP+IA+++ G D AD + P Sbjct: 61 AALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAA 120 Query: 111 SGAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXX 170 Q PLLA+GHAY+ WL ++ RVTLC+T DV++ AF +AA++A +W LP Sbjct: 121 IRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLPVVILVE 180 Query: 171 XXXXXXXXXRLRGAPGHGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQRARAGAGP 225 G H +R +P V+VDG+DV+AVR CVA AV RARAG GP Sbjct: 181 NIRGALSVH--LGRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVRARAGGGP 238 Query: 226 TVVRAITYRSSDFPSFD--GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARK 283 T+V+AITYR++DF D G D A +E FLDPL+F RL A G +L + ER A + Sbjct: 239 TLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDEQERAACQ 298 Query: 284 LVADAVALAKSGTCPGHDG 302 VADAVA AK+ P G Sbjct: 299 QVADAVAFAKARARPNGGG 317 >tr|A5U0N1|A5U0N1_MYCTA Tax_Id=419947 SubName: Full=Dehydrogenase E1 component;[Mycobacterium tuberculosis] Length = 334 Score = 249 bits (637), Expect = 2e-64 Identities = 151/326 (46%), Positives = 195/326 (59%), Gaps = 33/326 (10%) Query: 1 MTHASARPAALLPDHLE-MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGAT 59 MT S AA + D LE +YRRMWVLRLLDMALE++R +GL+ P+ GQEAVS+GA Sbjct: 1 MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAA 60 Query: 60 AALTEGDLVLASRRAHALHVGVDLPLGPMIAELI--------GQDSTCDHAD-QLNSPER 110 AAL EGD+++ + R HA HVG D PLGP+IA+++ G D AD + P Sbjct: 61 AALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAA 120 Query: 111 SGAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXX 170 Q PLLA+GHAY+ WL ++ RVTLC+T DV++ AF +AA++A +W LP Sbjct: 121 IRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLP------ 174 Query: 171 XXXXXXXXXRLRGAPG-------HGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQR 218 +RGA H +R +P V+VDG+DV+AVR CVA AV R Sbjct: 175 ---VVILVENIRGALSVHLDRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVR 231 Query: 219 ARAGAGPTVVRAITYRSSDFPSFD--GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCD 276 ARAG GPT+V+AITYR++DF D G D A +E FLDPL+F RL A G +L + Sbjct: 232 ARAGGGPTLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDE 291 Query: 277 VERTARKLVADAVALAKSGTCPGHDG 302 ER A + VADAVA AK+ P G Sbjct: 292 QERAACQQVADAVAFAKARARPNGGG 317 >tr|A1KGX5|A1KGX5_MYCBP Tax_Id=410289 SubName: Full=Probable dehydrogenase; EC=1.-.-.-;[Mycobacterium bovis] Length = 334 Score = 249 bits (637), Expect = 2e-64 Identities = 149/319 (46%), Positives = 192/319 (60%), Gaps = 19/319 (5%) Query: 1 MTHASARPAALLPDHLE-MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGAT 59 MT S AA + D LE +YRRMWVLRLLDMALE++R +GL+ P+ GQEAVS+GA Sbjct: 1 MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAA 60 Query: 60 AALTEGDLVLASRRAHALHVGVDLPLGPMIAELI--------GQDSTCDHAD-QLNSPER 110 AAL EGD+++ + R HA HVG D PLGP+IA+++ G D AD + P Sbjct: 61 AALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAA 120 Query: 111 SGAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXX 170 Q PLLA+GHAY+ WL ++ RVTLC+T DV++ AF +AA++A +W LP Sbjct: 121 IRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLPVVILVE 180 Query: 171 XXXXXXXXXRLRGAPGHGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQRARAGAGP 225 G H +R +P V+VDG+DV+AVR CVA AV RARAG GP Sbjct: 181 NIRGALSVH--LGRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVRARAGGGP 238 Query: 226 TVVRAITYRSSDFPSFD--GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARK 283 T+V+AITYR++DF D G D A +E FLDPL+F RL A G +L + ER A + Sbjct: 239 TLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDEQERAACQ 298 Query: 284 LVADAVALAKSGTCPGHDG 302 VADAVA AK+ P G Sbjct: 299 QVADAVAFAKARARPNGGG 317 >tr|A5WKL4|A5WKL4_MYCTF Tax_Id=336982 SubName: Full=Hypothetical dehydrogenase;[Mycobacterium tuberculosis] Length = 334 Score = 249 bits (637), Expect = 2e-64 Identities = 151/326 (46%), Positives = 195/326 (59%), Gaps = 33/326 (10%) Query: 1 MTHASARPAALLPDHLE-MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGAT 59 MT S AA + D LE +YRRMWVLRLLDMALE++R +GL+ P+ GQEAVS+GA Sbjct: 1 MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAA 60 Query: 60 AALTEGDLVLASRRAHALHVGVDLPLGPMIAELI--------GQDSTCDHAD-QLNSPER 110 AAL EGD+++ + R HA HVG D PLGP+IA+++ G D AD + P Sbjct: 61 AALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAA 120 Query: 111 SGAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXX 170 Q PLLA+GHAY+ WL ++ RVTLC+T DV++ AF +AA++A +W LP Sbjct: 121 IRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLP------ 174 Query: 171 XXXXXXXXXRLRGAPG-------HGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQR 218 +RGA H +R +P V+VDG+DV+AVR CVA AV R Sbjct: 175 ---VVILVENIRGALSVHLDRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVR 231 Query: 219 ARAGAGPTVVRAITYRSSDFPSFD--GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCD 276 ARAG GPT+V+AITYR++DF D G D A +E FLDPL+F RL A G +L + Sbjct: 232 ARAGGGPTLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDE 291 Query: 277 VERTARKLVADAVALAKSGTCPGHDG 302 ER A + VADAVA AK+ P G Sbjct: 292 QERAACQQVADAVAFAKARARPNGGG 317 >tr|A4KFF3|A4KFF3_MYCTU Tax_Id=395095 SubName: Full=Hypothetical dehydrogenase;[Mycobacterium tuberculosis str. Haarlem] Length = 334 Score = 249 bits (637), Expect = 2e-64 Identities = 151/326 (46%), Positives = 195/326 (59%), Gaps = 33/326 (10%) Query: 1 MTHASARPAALLPDHLE-MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGAT 59 MT S AA + D LE +YRRMWVLRLLDMALE++R +GL+ P+ GQEAVS+GA Sbjct: 1 MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAA 60 Query: 60 AALTEGDLVLASRRAHALHVGVDLPLGPMIAELI--------GQDSTCDHAD-QLNSPER 110 AAL EGD+++ + R HA HVG D PLGP+IA+++ G D AD + P Sbjct: 61 AALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAA 120 Query: 111 SGAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXX 170 Q PLLA+GHAY+ WL ++ RVTLC+T DV++ AF +AA++A +W LP Sbjct: 121 IRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLP------ 174 Query: 171 XXXXXXXXXRLRGAPG-------HGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQR 218 +RGA H +R +P V+VDG+DV+AVR CVA AV R Sbjct: 175 ---VVILVENIRGALSVHLDRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVR 231 Query: 219 ARAGAGPTVVRAITYRSSDFPSFD--GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCD 276 ARAG GPT+V+AITYR++DF D G D A +E FLDPL+F RL A G +L + Sbjct: 232 ARAGGGPTLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDE 291 Query: 277 VERTARKLVADAVALAKSGTCPGHDG 302 ER A + VADAVA AK+ P G Sbjct: 292 QERAACQQVADAVAFAKARARPNGGG 317 >tr|A2VGE1|A2VGE1_MYCTU Tax_Id=348776 SubName: Full=Putative uncharacterized protein;[Mycobacterium tuberculosis C] Length = 334 Score = 249 bits (637), Expect = 2e-64 Identities = 151/326 (46%), Positives = 195/326 (59%), Gaps = 33/326 (10%) Query: 1 MTHASARPAALLPDHLE-MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGAT 59 MT S AA + D LE +YRRMWVLRLLDMALE++R +GL+ P+ GQEAVS+GA Sbjct: 1 MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAA 60 Query: 60 AALTEGDLVLASRRAHALHVGVDLPLGPMIAELI--------GQDSTCDHAD-QLNSPER 110 AAL EGD+++ + R HA HVG D PLGP+IA+++ G D AD + P Sbjct: 61 AALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAA 120 Query: 111 SGAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXX 170 Q PLLA+GHAY+ WL ++ RVTLC+T DV++ AF +AA++A +W LP Sbjct: 121 IRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLP------ 174 Query: 171 XXXXXXXXXRLRGAPG-------HGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQR 218 +RGA H +R +P V+VDG+DV+AVR CVA AV R Sbjct: 175 ---VVILVENIRGALSVHLDRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVR 231 Query: 219 ARAGAGPTVVRAITYRSSDFPSFD--GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCD 276 ARAG GPT+V+AITYR++DF D G D A +E FLDPL+F RL A G +L + Sbjct: 232 ARAGGGPTLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDE 291 Query: 277 VERTARKLVADAVALAKSGTCPGHDG 302 ER A + VADAVA AK+ P G Sbjct: 292 QERAACQQVADAVAFAKARARPNGGG 317 >tr|Q7U150|Q7U150_MYCBO Tax_Id=1765 SubName: Full=PROBABLE DEHYDROGENASE; EC=1.-.-.-;[Mycobacterium bovis] Length = 334 Score = 249 bits (636), Expect = 3e-64 Identities = 149/319 (46%), Positives = 191/319 (59%), Gaps = 19/319 (5%) Query: 1 MTHASARPAALLPDHLE-MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGAT 59 MT S AA + D LE +YRRMWVLRLLDMALE++R +GL+ P+ GQEAVS+GA Sbjct: 1 MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAA 60 Query: 60 AALTEGDLVLASRRAHALHVGVDLPLGPMIAELI--------GQDSTCDHAD-QLNSPER 110 AAL EGD+++ + R HA HVG D PLGP+IA+++ G D AD + P Sbjct: 61 AALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAA 120 Query: 111 SGAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXX 170 Q PLLA+GHAY+ WL ++ RVTLC+T DV++ AF +AA++A +W LP Sbjct: 121 IRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLPVVILVE 180 Query: 171 XXXXXXXXXRLRGAPGHGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQRARAGAGP 225 G H +R +P V+VDG+DV+AVR CVA AV RARAG GP Sbjct: 181 NIRGALSVH--LGRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVRARAGGGP 238 Query: 226 TVVRAITYRSSDFPSFD--GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARK 283 T+V+AITYR++DF D G D A +E FLDPL+F RL A G +L + ER A + Sbjct: 239 TLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDEQERAACQ 298 Query: 284 LVADAVALAKSGTCPGHDG 302 VADAVA AK P G Sbjct: 299 QVADAVAFAKDRARPNGGG 317 >tr|A0QB51|A0QB51_MYCA1 Tax_Id=243243 SubName: Full=Dehydrogenase E1 component superfamily protein;[Mycobacterium avium] Length = 297 Score = 169 bits (429), Expect = 3e-40 Identities = 118/292 (40%), Positives = 147/292 (50%), Gaps = 33/292 (11%) Query: 14 DHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLAS-- 71 D LE YRRMWVLRLLDMAL+E ++ GQEAV++GA AAL GDLV A+ Sbjct: 8 DRLEPYRRMWVLRLLDMALDESAVGAAIDDDAPVDFGQEAVAVGAVAALRPGDLVNATTP 67 Query: 72 RRAHALHVGVDLPLGPMIAELIGQ-------DSTCDHADQLNSPERSGAADQCPLLAVGH 124 R HA +G+ LPLGP IAEL+G AD + A Q L A+G Sbjct: 68 RFRHAQQIGLGLPLGPAIAELLGTTRGGAGGSRKSGAADWKQALANESALGQSTLFALGD 127 Query: 125 AYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGA 184 A +Q + RVTLC D +S F AA +A W LP +RG Sbjct: 128 ANAQRMAGDGRVTLCAIAGSDTHSVEFATAAKIAASWRLP---------VVFVVQNVRGG 178 Query: 185 PGHGGDA--CQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFD 242 P A + +P VDG DV AV V AV+ A AG GP++V AITYR++ Sbjct: 179 PDARRCAYRSETMPMALVDGRDVVAVGDSVGQAVRHASAGDGPSLVEAITYRTNH----- 233 Query: 243 GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKS 294 +DPLV RL A G D +L +VER AR LVA+A+A AK+ Sbjct: 234 --------PVAIDPLVLARRRLMADGVDPDRLVEVERGARHLVAEAMACAKA 277 >tr|Q742Z7|Q742Z7_MYCPA Tax_Id=1770 SubName: Full=Putative uncharacterized protein;[Mycobacterium paratuberculosis] Length = 297 Score = 169 bits (427), Expect = 5e-40 Identities = 118/292 (40%), Positives = 147/292 (50%), Gaps = 33/292 (11%) Query: 14 DHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLAS-- 71 D LE YRRMWVLRLLDMAL+E ++ GQEAV++GA AAL GDLV A+ Sbjct: 8 DRLEPYRRMWVLRLLDMALDESGVGAAIDDDAPVDFGQEAVAVGAVAALRPGDLVNATTP 67 Query: 72 RRAHALHVGVDLPLGPMIAELIGQ-------DSTCDHADQLNSPERSGAADQCPLLAVGH 124 R HA +G+ LPLGP IAEL+G AD + A Q L A+G Sbjct: 68 RFRHAQQIGLGLPLGPAIAELLGTTRGGAGGSRKSGAADWKQALANESALGQSTLFALGD 127 Query: 125 AYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGA 184 A +Q + RVTLC D +S F AA +A W LP +RG Sbjct: 128 ANAQRMAGDGRVTLCAIAGSDTHSVEFATAAKIAASWRLP---------VVFVVQNVRGG 178 Query: 185 PGHGGDA--CQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFD 242 P A + +P VD DV AV V AV+RA AG GP++V AITYR++ Sbjct: 179 PDARRCAYRSETMPMALVDDRDVVAVGDSVGQAVRRASAGGGPSLVEAITYRTNH----- 233 Query: 243 GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKS 294 +DPLV RL A G D +L +VER AR LVA+A+A AK+ Sbjct: 234 --------PVAIDPLVLARRRLMADGIDPDRLVEVERGARHLVAEAMACAKA 277 >tr|A5V557|A5V557_SPHWW Tax_Id=392499 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring); EC=1.2.4.1;[Sphingomonas wittichii] Length = 331 Score = 121 bits (303), Expect = 1e-25 Identities = 100/303 (33%), Positives = 131/303 (43%), Gaps = 23/303 (7%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAH 75 LE YRRM +R + E + A G + + T GQEA +GA AL + D ++ + R+H Sbjct: 10 LEKYRRMQRIRQFEDLAEAIHAQGEIPGSLHTYAGQEASGVGACMALDDTDYMVGTHRSH 69 Query: 76 ALHVGVDLPLGPMIAELIGQ-DSTCD------HADQL---NSPERSGAADQCPLLAVGHA 125 + L P++AEL+G+ C H + E S P +A G A Sbjct: 70 GHPIAKGAKLRPLMAELLGKATGICKGKGGSMHLSDFSVGSLGETSIVGSGVP-VAAGAA 128 Query: 126 YSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAP 185 L + RV LC G N GAF + N+A +W LP P Sbjct: 129 LGSKLQGNGRVALCFFGDGATNEGAFHEGMNLAAVWALPAIFVCENNGYAVSTPASATVP 188 Query: 186 GHGGDACQR-----IPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPS 240 D +R +PS+ VDG DV AV VA AV RAR G GPT+V TYR +D Sbjct: 189 VK--DVAERARAYGMPSIIVDGQDVDAVEAAVAEAVGRARTGGGPTLVETKTYRYADHAV 246 Query: 241 FDG----DYDAAATE-PFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKSG 295 G D E DPL +L AGG AA L +ER VADA+ A+ Sbjct: 247 NMGRVLLDRGGEVDEWRKRDPLALYRAKLIAGGTAAALLDAIEREVADEVADALQFARDS 306 Query: 296 TCP 298 P Sbjct: 307 AWP 309 >tr|C8XE57|C8XE57_NAKMY Tax_Id=479431 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring); EC=1.2.4.1;[Nakamurella multipartita] Length = 339 Score = 109 bits (273), Expect = 3e-22 Identities = 85/261 (32%), Positives = 120/261 (45%), Gaps = 22/261 (8%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAH 75 +EM RRM +R D +M G + V T++GQEA +GAT AL E D + + R+H Sbjct: 11 VEMQRRMLRIRRFDERASKMVKRGAIPGTVHTSIGQEAQVVGATMALGEHDYMTGNHRSH 70 Query: 76 ALHVGVDLPLGPMIAELIGQ-DSTCD------HADQLN--SPERSGAADQCPLLAVGHAY 126 +G PLGP++AEL+G+ C H N S SG +A G A Sbjct: 71 GHPIGKGSPLGPLMAELVGKAGGVCGGKGGSLHLADFNVGSLGESGIVGSSIPIATGAAL 130 Query: 127 SQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAPG 186 S + + +V+L G N G ++ N+A +W LP G Sbjct: 131 SSKVLGNGKVSLAFFGDGAANQGCLYESLNIAGVWKLPVIFLCENNQYALSTQAWTVTSG 190 Query: 187 HGGD--ACQRIPSVTVD-GHDVQAVRRCVATAVQRARAGAGPTVVRAITYR--------- 234 D A IP V V+ G D+ AV V+TAV RARAG GPT+V +TYR Sbjct: 191 VIADRAAGFGIPGVRVENGQDIMAVYDAVSTAVDRARAGEGPTLVEVVTYRYNEHSEGLR 250 Query: 235 -SSDFPSFDGDYDAAATEPFL 254 ++D+ + D D A +P + Sbjct: 251 LATDYRNADEKADWLARDPIV 271 >tr|B9LC81|B9LC81_CHLSY Tax_Id=480224 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring); EC=1.2.4.1;[Chloroflexus aurantiacus] Length = 334 Score = 105 bits (262), Expect = 7e-21 Identities = 92/303 (30%), Positives = 138/303 (45%), Gaps = 23/303 (7%) Query: 17 EMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHA 76 E RM ++R + EE+ A GL+ + ++GQEAV+IGA+AA+ GD +L R H Sbjct: 29 EWVLRMQIIRAFEEKAEELFARGLVHGTMHLSIGQEAVAIGASAAMKPGDYLLNHHRGHG 88 Query: 77 --LHVGVDLPLGPMIAELIGQDSTCDHAD---------QLNSPERSGAADQCPLLAVGHA 125 L G D+ L M+AE +G+++ ++N+ +G ++VG Sbjct: 89 HCLAWGSDVRL--MMAEFLGKETGYCRGRGGSMHIANVEMNNLGANGIVGGGIPISVGVG 146 Query: 126 YSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAP 185 S S +V L I G VN+GAF ++ NMA +W+LP + Sbjct: 147 LSIKKRRSSQVCLTIFGDGAVNTGAFHESLNMASIWNLPVVYLCENNQYAMSMPIQKACR 206 Query: 186 -GHGGD--ACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFD 242 H A I +TVDG+D AV V AV RAR+G GPT+V AITYR D Sbjct: 207 LNHLSQRAAAYAIAGITVDGNDALAVYEAVRQAVARARSGYGPTLVEAITYRWKGHSKSD 266 Query: 243 ----GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKSGTCP 298 D DP++ ++ A+ + D AR ++ +AV A++ P Sbjct: 267 RQAYRSRDEVKDWQSRDPIMRLARLIQMSDAEFKAIVD---QARTMIEEAVEFAQASPEP 323 Query: 299 GHD 301 D Sbjct: 324 DPD 326 >tr|A9W9S7|A9W9S7_CHLAA Tax_Id=324602 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring); EC=1.2.4.1;[Chloroflexus aurantiacus] Length = 334 Score = 105 bits (262), Expect = 7e-21 Identities = 92/303 (30%), Positives = 138/303 (45%), Gaps = 23/303 (7%) Query: 17 EMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHA 76 E RM ++R + EE+ A GL+ + ++GQEAV+IGA+AA+ GD +L R H Sbjct: 29 EWVLRMQIIRAFEEKAEELFARGLVHGTMHLSIGQEAVAIGASAAMKPGDYLLNHHRGHG 88 Query: 77 --LHVGVDLPLGPMIAELIGQDSTCDHAD---------QLNSPERSGAADQCPLLAVGHA 125 L G D+ L M+AE +G+++ ++N+ +G ++VG Sbjct: 89 HCLAWGSDVRL--MMAEFLGKETGYCRGRGGSMHIANVEMNNLGANGIVGGGIPISVGVG 146 Query: 126 YSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAP 185 S S +V L I G VN+GAF ++ NMA +W+LP + Sbjct: 147 LSIKKRRSSQVCLTIFGDGAVNTGAFHESLNMASIWNLPVVYLCENNQYAMSMPIQKACR 206 Query: 186 -GHGGD--ACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFD 242 H A I +TVDG+D AV V AV RAR+G GPT+V AITYR D Sbjct: 207 LNHLSQRAAAYAIAGITVDGNDALAVYEAVRQAVARARSGYGPTLVEAITYRWKGHSKSD 266 Query: 243 ----GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKSGTCP 298 D DP++ ++ A+ + D AR ++ +AV A++ P Sbjct: 267 RQAYRSRDEVKDWQSRDPIMRLARLIQMSDAEFKAIVD---QARTMIEEAVEFAQASPEP 323 Query: 299 GHD 301 D Sbjct: 324 DPD 326 >tr|B5HWC3|B5HWC3_9ACTO Tax_Id=463191 SubName: Full=Pyruvate dehydrogenase;[Streptomyces sviceus ATCC 29083] Length = 325 Score = 102 bits (254), Expect = 6e-20 Identities = 90/303 (29%), Positives = 135/303 (44%), Gaps = 23/303 (7%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAH 75 L +Y +M ++R + A ++ GL++ A G EA+++GA+AAL + D V A+ R H Sbjct: 7 LALYEQMVLIRRTEKAAHDLFLQGLVKGTTHLAAGHEAIAVGASAALRDDDYVFATYRGH 66 Query: 76 ALHVGVDLPLGPMIAELIGQDS------------TCDHADQLNSPERSGAADQCPLLAVG 123 + +AEL+ + + T + L S GA P +AVG Sbjct: 67 HHAMARGATPEECLAELMSRATGLCGAKGGSMHLTKAATNMLGSYAIVGA--HLP-MAVG 123 Query: 124 HAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLP--XXXXXXXXXXXXXXXRL 181 A+S L + ++ + G N GAF +A N+A +W LP + Sbjct: 124 AAWSAKLRGTGQLAVAFFGDGATNIGAFHEALNLAAVWKLPVLFVCENNLYMEYTPIADV 183 Query: 182 RGAPGHGGDACQR--IPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFP 239 P D IP VDG+DV +V+ VA +RARAG GP ++ A TYR Sbjct: 184 TAVPRPAADRAPAYGIPGEVVDGNDVVSVQETVARLARRARAGDGPALLEAETYRHFGHS 243 Query: 240 SFD-GDY-DAAATEPFL--DPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKSG 295 D Y A E +L DPL GRL G ++ + + AR +V +AV AK+ Sbjct: 244 RTDPATYRPAEEVERWLKHDPLDIARGRLVEAGVPEERVAEADERARTVVQEAVEAAKNA 303 Query: 296 TCP 298 P Sbjct: 304 PPP 306 >tr|Q28MR4|Q28MR4_JANSC Tax_Id=290400 SubName: Full=Dehydrogenase E1 component;[Jannaschia sp.] Length = 675 Score = 101 bits (252), Expect = 9e-20 Identities = 87/316 (27%), Positives = 135/316 (42%), Gaps = 27/316 (8%) Query: 6 ARPAALLPDHLEMYRRMWV-LRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTE 64 A P L P L +M + +R + +E+ G+++ +++GQEA++ GA A L Sbjct: 13 ATPNGLAPKDLRAALKMMLRIRRFETRAKELFLQGVIKGTAHSSVGQEAIAAGACAVLEP 72 Query: 65 GDLVLASRRAHALHVGVDLPLGPMIAELIGQDSTCDHADQLNSPERSGAADQCPL----- 119 D +L R H + LG M AEL+G+++ + L D+ L Sbjct: 73 ADFILTHHRGHGHTIAKGADLGRMFAELMGRET--GYCAGLGGSMHIADFDRGILGANGI 130 Query: 120 ------LAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXX 173 L G A ++ LD + + + G N G F +A N+A +W LP Sbjct: 131 VGAGIGLGTGAALAEQLDATGAIGISFFGDGAANEGIFHEAMNLAAIWKLPLIFFCENNQ 190 Query: 174 XXXXXXRLRGAPGHG----GDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVR 229 G GDA +P+ +DG+D+ AV V+ A RARAG GPT++ Sbjct: 191 YGLTTPTTAVTAGPSIAARGDA-YGVPNEQIDGNDLPAVHMAVSRAALRARAGDGPTLIE 249 Query: 230 AITYRSSD------FPSFDGDYDAAATEPFLDPLV-FTGGRLKAGGADAAQLCDVERTAR 282 A+TYR D P++ + + A + DP+V K G DAA + A Sbjct: 250 ALTYRWDDHSMRANLPAYRSEAEEEAWKS-QDPIVRLEADMSKLGELDAASYAALNDEAE 308 Query: 283 KLVADAVALAKSGTCP 298 V A+ A+S P Sbjct: 309 ADVEAAIEWARSQAEP 324 >tr|A4AFX0|A4AFX0_9ACTN Tax_Id=312284 SubName: Full=Acetoin dehydrogenase (TPP-dependent) alpha chain;[marine actinobacterium PHSC20C1] Length = 327 Score = 100 bits (248), Expect = 3e-19 Identities = 94/312 (30%), Positives = 133/312 (42%), Gaps = 22/312 (7%) Query: 1 MTHASARPAALLP---DHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIG 57 MT+ P P D LE+ R M+ +R + + + + L+ GQEAV++G Sbjct: 1 MTYHPVNPTLADPLPADALELLRSMYEIRFFEDEIMGLFSQNLVRGSTHLCQGQEAVTVG 60 Query: 58 ATAALTEGDLVLASRRAHALHVGVDLPLGPMIAELIGQ--------DSTCDHADQLNSPE 109 +AL+ GD + + R H + + PL E++G+ + AD Sbjct: 61 VCSALSPGDTMTCTYRGHGAVLAMGAPLDRAFGEILGRAGGLCGGKGGSMHLADVSVGAL 120 Query: 110 RSGAADQCPL-LAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXX 168 S A L VG A + + V++ G N GAF ++ N+A +W LP Sbjct: 121 GSNAIVGGHLPTTVGAALAASYRGTSEVSVAFFGDGSTNIGAFHESLNLASIWKLPAIFV 180 Query: 169 XXXXXXXXXXXRLRGAPGH---GGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGP 225 P A +P V VDG+DV A+R TAV+RARAG GP Sbjct: 181 IENNQYGEYSTLASTTPIERLSDRAASYGMPGVFVDGNDVIAMRSATKTAVERARAGEGP 240 Query: 226 TVVRAITYRSSDFPSFDGDYDAAATEP----FLDPLVFTGGRLKA-GGADAAQLCDVERT 280 T++ A TYR S D E DP+V ++A GGADAA +VERT Sbjct: 241 TLIEADTYRHSGHSRSDPAKYRPEEEVKSWFARDPIVQLRNAIEASGGADAA--AEVERT 298 Query: 281 ARKLVADAVALA 292 A V A LA Sbjct: 299 AHTDVDAARDLA 310 >tr|C5NUE3|C5NUE3_9BACL Tax_Id=546270 (acoA)SubName: Full=TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit; EC=1.1.1.-;[Gemella haemolysans ATCC 10379] Length = 326 Score = 99.8 bits (247), Expect = 4e-19 Identities = 81/307 (26%), Positives = 136/307 (44%), Gaps = 36/307 (11%) Query: 14 DHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRR 73 +HLEMY M ++R DM L ++ + GL+ ++G+EA ++GA L + DL+ ++ R Sbjct: 12 EHLEMYELMQLIRDFDMELSKLYSRGLVHGMTHYSVGEEAANVGAIYPLRKEDLMFSNHR 71 Query: 74 AHALHVGVDLPLGPMIAELIGQDS-TCD------HADQLNSPER--SGAADQCPLLAVGH 124 H + + + M+AE++G+++ C H L +G L+ G Sbjct: 72 GHGQTIAKGIEIDRMMAEILGKETGQCKGRGGSMHIYDLEHGNMGCNGIVGGGHGLSTGA 131 Query: 125 AYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGA 184 A +Q + + + +C G N G+F + NMA W LP + R Sbjct: 132 ALAQKMKKTGNIVICCMGDGATNEGSFHECLNMASNWDLPLIFYVINNKYGISMAQER-- 189 Query: 185 PGHGGDACQRIPSVT-------------VDGHDVQAVRRCVATAVQRARAGAGPTVVRAI 231 C R+ +T DG+DV AV + A++ R+G GP +V A+ Sbjct: 190 -------CMRVKEITERAASYRIKGIHVPDGNDVLAVYDAMQEAIEHTRSGKGPVLVEAV 242 Query: 232 TYRSSDFPSFD-GDY---DAAATEPFLDPLV-FTGGRLKAGGADAAQLCDVERTARKLVA 286 +YR + D G Y + A DP V + L+ G A +L ++E ++ + Sbjct: 243 SYRWFGHSASDAGKYRSREEVAEWKLKDPNVKYKNYLLENGIATEEELKEIEDRSKATID 302 Query: 287 DAVALAK 293 DAV AK Sbjct: 303 DAVEFAK 309 >tr|Q46RB0|Q46RB0_RALEJ Tax_Id=264198 SubName: Full=Pyruvate dehydrogenase (Lipoamide); EC=1.2.4.1;[Ralstonia eutropha] Length = 366 Score = 99.4 bits (246), Expect = 5e-19 Identities = 86/291 (29%), Positives = 124/291 (42%), Gaps = 14/291 (4%) Query: 8 PAALLPDHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDL 67 P ALLP +YR M + R D+ M+ G + + ++ALGQEAV +G +A+ D+ Sbjct: 35 PDALLP----LYRAMVLTRQFDLKAIAMQRTGKIGT-FASALGQEAVGVGVASAMRPEDI 89 Query: 68 VLASRRAHALHVGVDLPLGPMIAELIGQDSTCDHADQLNSPERSGAADQCPLLAVGHAYS 127 ++ S R HA + + + G + A + + A G AY+ Sbjct: 90 LVPSYRDHAAQFVRGVTMTESLLYWGGDERGSGFAAAPHDFGNNVPIGTQVCHAAGVAYA 149 Query: 128 QWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAPGH 187 L RV +C+ G + G F + NMA WH P R R H Sbjct: 150 VQLRGEPRVAVCMLGDGGTSKGDFYEGMNMAGAWHAPLVIVVNNNQWAISMPRSRQTAAH 209 Query: 188 G---GDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFDG- 243 IP +DG+DV AVR V A++RARAG GP+++ AITYR D + D Sbjct: 210 TLAQKAIAAGIPGEQIDGNDVVAVRHRVGEAIERARAGEGPSLIEAITYRLGDHTTADDA 269 Query: 244 ----DYDAAATEPFLDPLVFTGGRL-KAGGADAAQLCDVERTARKLVADAV 289 D +PL+ L K G DA + + R + VA AV Sbjct: 270 SRYRDESTVKAHWQAEPLLRLREHLVKLGAWDAGREEALVRECSQQVAQAV 320 >tr|D1C9N9|D1C9N9_9CHLR Tax_Id=479434 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring); EC=1.2.4.1;[Sphaerobacter thermophilus DSM 20745] Length = 345 Score = 98.6 bits (244), Expect = 8e-19 Identities = 90/313 (28%), Positives = 134/313 (42%), Gaps = 34/313 (10%) Query: 16 LEMYRRMWVLRLLDMALEEM----------RADGLMESPVSTALGQEAVSIGATAALTEG 65 L YR+M ++R + + E A G + + A+GQEAV++G + LT+ Sbjct: 26 LAQYRQMCLIRDFEELIAERYAIGKTPNFNMAAGPIRGEMHLAVGQEAVAVGVCSLLTDA 85 Query: 66 DLVLASRRAH--ALHVGVDLPLGPMIAELIGQDSTC-----DHADQLNSPER---SGAAD 115 D V+++ R H AL G+D G + AE+ G+++ H ++ + SG Sbjct: 86 DAVVSTHRPHHHALAKGIDP--GRLAAEIFGKNTGLCRGKGGHMHLFDAEKNFSCSGIVG 143 Query: 116 QCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXX 175 A G A+S V + +G N G F + A LW LP Sbjct: 144 ASYPQAAGAAFSFRAQGQPNVAVAFSGEGAANHGTFSETLTAAALWQLPLVIVIEDNLYA 203 Query: 176 XXXXRLRG-APGHGGDACQ--RIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAIT 232 + A H Q +P+ VDG DV V A++RARAG GPTV+ A+ Sbjct: 204 DSTPKWAALASTHQSHRAQAYNVPAYLVDGMDVIDVYAAAKRAIERARAGHGPTVIEAVC 263 Query: 233 YRSSDFPSFDGDYDAAATEP------FLDPLVFTGGRL-KAGGADAAQLCDVERTARKLV 285 YR F+GD + T LDP+ G RL + G AD A L ++ A + Sbjct: 264 YRYRG--HFEGDGEDYRTREEVELWRTLDPIERLGKRLIRLGWADDATLAELREEAARDA 321 Query: 286 ADAVALAKSGTCP 298 A A+A A+ P Sbjct: 322 AQAIAFAEESPLP 334 >tr|A9HDU8|A9HDU8_9RHOB Tax_Id=391595 SubName: Full=Acetoin dehydrogenase (TPP-dependent) alpha chain;[Roseobacter litoralis Och 149] Length = 335 Score = 98.2 bits (243), Expect = 1e-18 Identities = 72/227 (31%), Positives = 107/227 (47%), Gaps = 12/227 (5%) Query: 20 RRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHALHV 79 R+M+++R + E+ GL+ + ++GQEA ++G+ +L++ D + ++ R H V Sbjct: 24 RKMFLIRKFEEGAEDSYTRGLIHGTMHLSIGQEASAVGSCMSLSDDDKITSTHRGHGHCV 83 Query: 80 GVDLPLGPMIAELIG-QDSTCD------HADQLNSPE--RSGAADQCPLLAVGHAYSQWL 130 LG M AE G +D C H + +G +AVG A S Sbjct: 84 AKGADLGRMFAEFFGKEDGYCRGRGGSMHIADVAKGNLGANGIVGGGLPIAVGAALSAKR 143 Query: 131 DNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRG-APGHGG 189 + VT+C G N GAF +A NMA +W LP + A H Sbjct: 144 LGTGAVTVCFFGDGANNEGAFHEALNMAAIWKLPVVFVCENNRYGMSTSTEKSTAVKHIA 203 Query: 190 D--ACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR 234 + A +P VTVDG+D AV V +AV RARAG GP++V +TYR Sbjct: 204 ERAAAYNMPGVTVDGNDFSAVTEAVDSAVARARAGDGPSLVENLTYR 250 >tr|Q1ARM0|Q1ARM0_RUBXD Tax_Id=266117 SubName: Full=Pyruvate dehydrogenase (Lipoamide); EC=1.2.4.1;[Rubrobacter xylanophilus] Length = 332 Score = 97.1 bits (240), Expect = 2e-18 Identities = 86/302 (28%), Positives = 130/302 (43%), Gaps = 23/302 (7%) Query: 18 MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHAL 77 M R M +R + L E+ G + V +G+EAV++GA +AL E D + ++ R H Sbjct: 10 MLRLMLRIRRFEEKLAELFKRGKLPGFVHLYIGEEAVAVGACSALREDDRITSTHRGHGH 69 Query: 78 HVGVDLPLGPMIAELIGQDS-----------TCDHADQLNSPERSGAADQCPLLAVGHAY 126 + + M+AEL+G+++ T D + L +G +AVG A+ Sbjct: 70 VIAKGADVSRMMAELLGKEAGYCRGKGGSMHTVDFS--LGIMGTNGIVGGGIPIAVGSAW 127 Query: 127 SQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAPG 186 D VT+ G N G F + N+A +W LP + G Sbjct: 128 GDRQLGRDTVTVSFFGDGASNQGVFFEGMNLAAIWKLPVIFLCENNGYTEWTPTEKLTAG 187 Query: 187 HGGDACQR--IPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR----SSDFPS 240 D IPSV VDG+DV +V V+ AV RARAG GP+++ A TYR + + Sbjct: 188 RISDRGVPFGIPSVQVDGNDVISVHEAVSEAVGRARAGEGPSLIEARTYRWHGHNEGEEA 247 Query: 241 FDGDY---DAAATEPFLDPLVFTGGRLKAGGADAAQLCD-VERTARKLVADAVALAKSGT 296 F G Y + DP+ RL G A + + V+ ++ + DAV A Sbjct: 248 FSGPYRPEEEIEEWKGKDPITTFAARLVEQGVFAREEIERVDAEEKERIEDAVRFAVESA 307 Query: 297 CP 298 P Sbjct: 308 YP 309 >tr|Q74AD3|Q74AD3_GEOSL Tax_Id=35554 SubName: Full=Dehydrogenase complex, E1 component, alpha subunit;[Geobacter sulfurreducens] Length = 325 Score = 96.7 bits (239), Expect = 3e-18 Identities = 96/312 (30%), Positives = 136/312 (43%), Gaps = 21/312 (6%) Query: 10 ALLPDH--LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDL 67 A+LPD L+M+ +M + R + + E G + + GQEAV++GATAAL + D Sbjct: 7 AILPDSELLKMHEQMVLSREFEESCAEQYTKGHITGFLHLYSGQEAVAVGATAALRKDDY 66 Query: 68 VLASRRAHALHVGVDLPLGPMIAELIGQ-DSTCD------HADQLNSPERSGAA---DQC 117 +L++ R HA + ++AEL G+ C H + G A Q Sbjct: 67 ILSAYREHAQAIVRGAEPRRVMAELFGKATGMCKGKGGSMHLFDPSLAFMGGYAIVGGQF 126 Query: 118 PLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXX 177 P +AVG A++ R++ C G VN G F ++ N A LW LP Sbjct: 127 P-IAVGLAFASKYRKEGRISACFFGDGAVNQGTFHESLNWARLWELPVLFICENNFYGIG 185 Query: 178 XXRLRG---APGHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR 234 R + H IPSV VDG DV AV V + R + P ++ A+TYR Sbjct: 186 TAVSRASALSDIHKRTCGYDIPSVRVDGMDVMAVHEAVKWGAEWVREHSRPYLIEAMTYR 245 Query: 235 SSDFPSFD-GDYDAAATEPF---LDPLV-FTGGRLKAGGADAAQLCDVERTARKLVADAV 289 D G Y +AA DP+ F ++ G A A+L V R +VADAV Sbjct: 246 FRGHSMADPGKYRSAAEVELWKSRDPIPNFEKRLVEEGIATEAELAAVLEKCRGVVADAV 305 Query: 290 ALAKSGTCPGHD 301 A A+ P D Sbjct: 306 AFAEESPWPEDD 317 >sp|O31404|ACOA_BACSU Tax_Id=1423 (acoA)RecName: Full=Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; Short=Acetoin:DCPIP oxidoreductase-alpha; Short=Ao:DCPIP OR; EC=1.1.1.-; AltName: Full=TPP-dependent acetoin dehydrogenase E1 subunit alpha;[Bacillus subtilis] Length = 333 Score = 96.3 bits (238), Expect = 4e-18 Identities = 85/312 (27%), Positives = 134/312 (42%), Gaps = 42/312 (13%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAH 75 L MY++M +R + + E+ A G++ V G+EAV++G A L +GD + ++ R H Sbjct: 17 LWMYQKMLEIRGFEDKVHELFAQGVLPGFVHLYAGEEAVAVGVCAHLHDGDSITSTHRGH 76 Query: 76 ALHVGVDLPLGPMIAELIGQDS-TCD------HADQLNSPE--RSGAADQCPLLAVGHAY 126 + L M+AE+ G+ + C H L+ +G LA G A Sbjct: 77 GHCIAKGCDLDGMMAEIFGKATGLCKGKGGSMHIADLDKGMLGANGIVGGGFTLACGSAL 136 Query: 127 SQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAPG 186 + + V++C G N G F + N+A +W+LP P Sbjct: 137 TAKYKQTKNVSVCFFGDGANNQGTFHEGLNLAAVWNLPVVFVAENNGYG------EATPF 190 Query: 187 HGGDACQRI---------PSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSD 237 AC I P VTVDG D+ AV + A++RAR G GP+++ +TYR + Sbjct: 191 EYASACDSIADRAAAYNMPGVTVDGKDILAVYQAAEEAIERARNGGGPSLIECMTYR--N 248 Query: 238 FPSFDGDYDAAATEPFLDPLV-----------FTGGRLKAGGADAAQLCDVERTARKLVA 286 + F+GD A T D V F LK DA +L D+E+ + + Sbjct: 249 YGHFEGD---AQTYKTKDERVEHLEEKDAIQGFKNYLLKE--TDANKLSDIEQRVSESIE 303 Query: 287 DAVALAKSGTCP 298 AV+ ++ P Sbjct: 304 KAVSFSEDSPYP 315 >tr|A1SN84|A1SN84_NOCSJ Tax_Id=196162 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring); EC=1.2.4.1;[Nocardioides sp.] Length = 344 Score = 96.3 bits (238), Expect = 4e-18 Identities = 88/309 (28%), Positives = 130/309 (42%), Gaps = 28/309 (9%) Query: 16 LEMYRRMWVLRLLDMA-LEEMRAD---------GLMESPVSTALGQEAVSIGATAALTEG 65 L++Y M + R + A L E AD GL+ + + GQE V+ G A LT Sbjct: 27 LDLYETMVLSRTYEEAILREYHADKGPGFDIGKGLIPGEMHLSAGQEPVAAGVCAHLTTD 86 Query: 66 DLVLASRRAHALHVGVDLPLGPMIAELIGQDSTCDHAD----QLNSPER----SGAADQC 117 D V A+ R H V + L M AE+ G++ L P+ SG + Sbjct: 87 DAVTATHRPHHFAVAHGVDLRRMTAEIFGREDGLGRGRGGHMHLFDPDTHFSCSGIIAEG 146 Query: 118 PLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXX 177 A+G A++ +DR+ + +TG N GAF ++ N+A W LP Sbjct: 147 YPPALGQAFAFHRQGTDRIAVAVTGEGAANQGAFHESLNLAARWSLPVVFVVEDNDWGIS 206 Query: 178 XXRLRG---APGHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR 234 R A A IP ++G+DV+ V AV RARAG GP+++ T R Sbjct: 207 VPRTASTSVASNADRAAAYGIPGERIEGNDVEGVYDAARRAVARARAGEGPSLIEVHTLR 266 Query: 235 SSDFPSFDGDYDAAATE----PFLDPLVFTGGRLK-AGGADAAQLCDVERTARKLVADAV 289 + F+GD + P DP+ RL+ AG D + + A + DA+ Sbjct: 267 L--WGHFEGDAQGYRLDLEDAPSHDPIPRYETRLREAGVLDDETVTRIRSAASERTEDAI 324 Query: 290 ALAKSGTCP 298 A AK+ P Sbjct: 325 AFAKNSPVP 333 >tr|Q8YTK9|Q8YTK9_ANASP Tax_Id=103690 SubName: Full=Pyruvate dehydrogenase E1 component, alpha subunit;[Anabaena sp.] Length = 344 Score = 95.5 bits (236), Expect = 7e-18 Identities = 92/308 (29%), Positives = 129/308 (41%), Gaps = 25/308 (8%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEG-DLVLASRRA 74 L +Y M + R + EM G M V GQEAVS G A+ G D V ++ R Sbjct: 23 LLLYEDMTLGRFFEDKCAEMYYRGKMFGFVHLYNGQEAVSTGVIQAMRPGEDFVSSTYRD 82 Query: 75 HALHVGVDLPLGPMIAELIGQDSTCDHAD----QLNSPER------SGAADQCPLLAVGH 124 H + +P ++AEL G+ + C + S E + A+ P+ A Sbjct: 83 HVHALSAGVPAREVMAELFGKATGCSKGRGGSMHMFSAEHGLLGGYAFVAEGIPVAAGAA 142 Query: 125 AYSQWL------DNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXX 178 S++ N+D+VT C G N+G F + NMA LW LP Sbjct: 143 FQSKYRREVLGDPNADQVTACFFGDGAANNGQFFETLNMAALWKLPIIFVVENNKWAIGM 202 Query: 179 XRLRGAPG---HGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRS 235 R + + + V VDG DV AVR AV RARAG GPT++ A+TYR Sbjct: 203 AHDRATSDPEIYKKASVFNMVGVEVDGMDVLAVRAVAQEAVARARAGEGPTLIEALTYRF 262 Query: 236 SDFPSFDGDYDAAATEPFL----DPLVFTGGRL-KAGGADAAQLCDVERTARKLVADAVA 290 D D + E DP+ L + AD A+L +ER + ++ DAV Sbjct: 263 RGHSLADPDEMRSKAEKEFWFSRDPIKKLAAYLIEQNLADEAELKAIERKIQDVIDDAVK 322 Query: 291 LAKSGTCP 298 A+S P Sbjct: 323 FAESSPEP 330 >tr|Q8RD61|Q8RD61_THETN Tax_Id=119072 (AcoA)SubName: Full=Thiamine pyrophosphate-dependent dehydrogenases, E1 component alpha subunit;[Thermoanaerobacter tengcongensis] Length = 333 Score = 95.5 bits (236), Expect = 7e-18 Identities = 72/237 (30%), Positives = 108/237 (45%), Gaps = 24/237 (10%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAH 75 L MY++M +R ++ +E+ ++ +G+EA ++GA AAL D + ++ R H Sbjct: 19 LWMYKKMVQIRQFELKTDELYKKNMIWGTYHLYVGEEAAAVGACAALEPTDYITSTHRGH 78 Query: 76 ALHVGVDLPLGPMIAELIGQDS--------TCDHADQLNSP-ERSGAADQCPLLAVGHAY 126 + L M+AEL+G+++ + AD +G +A G A Sbjct: 79 GHTIAKGADLKRMMAELLGKETGHCKGRGGSMHIADIFTGHLGANGIVAGGIPIATGAAL 138 Query: 127 SQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAPG 186 + L RVTLC G N+GAF ++ NMA +W LP AP Sbjct: 139 ASKLRGDKRVTLCFFGDGAANTGAFNESLNMAAIWQLPVVYFCENNQY------AMSAPV 192 Query: 187 HGGDACQRI---------PSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR 234 + A + I P V VDG+DV V + V AV RAR G GPT++ A TYR Sbjct: 193 NKFTAVKNIADRAASYNMPGVIVDGNDVLEVYKAVKEAVDRARKGEGPTLIEAKTYR 249 >tr|Q3M561|Q3M561_ANAVT Tax_Id=240292 SubName: Full=Dehydrogenase, E1 component; EC=1.2.4.1;[Anabaena variabilis] Length = 344 Score = 95.5 bits (236), Expect = 7e-18 Identities = 92/308 (29%), Positives = 129/308 (41%), Gaps = 25/308 (8%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEG-DLVLASRRA 74 L +Y M + R + EM G M V GQEAVS G A+ G D V ++ R Sbjct: 23 LLLYEDMTLGRFFEDKCAEMYYRGKMFGFVHLYNGQEAVSTGVIQAMRPGEDFVSSTYRD 82 Query: 75 HALHVGVDLPLGPMIAELIGQDSTCDHAD----QLNSPER------SGAADQCPLLAVGH 124 H + +P ++AEL G+ + C + S E + A+ P+ A Sbjct: 83 HVHALSAGVPAREVMAELFGKATGCSKGRGGSMHMFSAEHGLLGGYAFVAEGIPVAAGAA 142 Query: 125 AYSQWL------DNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXX 178 S++ N+D+VT C G N+G F + NMA LW LP Sbjct: 143 FQSKYRREVLGDPNADQVTACFFGDGAANNGQFFETLNMAALWKLPIIFVVENNKWAIGM 202 Query: 179 XRLRGAPG---HGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRS 235 R + + + V VDG DV AVR AV RARAG GPT++ A+TYR Sbjct: 203 AHDRATSDPEIYKKASVFNMVGVEVDGMDVLAVRAVAQEAVARARAGEGPTLIEALTYRF 262 Query: 236 SDFPSFDGDYDAAATEPFL----DPLVFTGGRL-KAGGADAAQLCDVERTARKLVADAVA 290 D D + E DP+ L + AD A+L +ER + ++ DAV Sbjct: 263 RGHSLADPDEMRSKAEKEFWFSRDPIKKLAAYLIEQNLADEAELKAIERKIQDVIDDAVK 322 Query: 291 LAKSGTCP 298 A+S P Sbjct: 323 FAESSPEP 330 >tr|A3U0V2|A3U0V2_9RHOB Tax_Id=252305 SubName: Full=Acetoin dehydrogenase (TPP-dependent) alpha chain;[Oceanicola batsensis HTCC2597] Length = 339 Score = 95.5 bits (236), Expect = 7e-18 Identities = 86/295 (29%), Positives = 131/295 (44%), Gaps = 20/295 (6%) Query: 22 MWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRR--AHALHV 79 MW +RL + E + +GL+ + ++GQEAV+ G L + DL+L++ R H L Sbjct: 27 MWKIRLFEETAIEAQREGLVLGAIHPSIGQEAVAAGICPNLRQADLLLSTHRGHGHTLAK 86 Query: 80 GVDLPLGPMIAELIGQ-DSTCDH-------AD-QLNSPERSGAADQCPLLAVGHAYSQWL 130 G D PL M+ EL G+ + TC AD + +G + VG A++ + Sbjct: 87 GAD-PLA-MMMELFGRAEGTCGGKGGSMHIADFGVGMLGANGVVGANITIGVGAAHALKM 144 Query: 131 DNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLP--XXXXXXXXXXXXXXXRLRGAPGHG 188 SD + +CI G +N G F++ N A ++ LP L G PG Sbjct: 145 RRSDDIAVCIFGDGAINRGPFLEGLNWARVYDLPVLFVCEDNGFSATTRTRTLTGGPGAV 204 Query: 189 GDA-CQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFD-GDY- 245 A +P+ VDG+DV V TA+ R G GP ++ TYR + + D Y Sbjct: 205 ARAESLGLPAEEVDGNDVLGVDAAARTAIDAIRQGGGPRFLQCRTYRMTGHTAVDPATYR 264 Query: 246 DAAATEPFLD--PLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKSGTCP 298 DAA E + P+ G L+ G D A++ A + + D A A+ P Sbjct: 265 DAAEVEEWRAHCPIARLEGALRLAGVDEARMQQQRTEAEQYMQDVYARARDAEWP 319 >tr|Q2JWW4|Q2JWW4_SYNJA Tax_Id=321327 SubName: Full=Dehydrogenase E1 component, alpha subunit;[Synechococcus sp.] Length = 333 Score = 95.1 bits (235), Expect = 9e-18 Identities = 82/250 (32%), Positives = 108/250 (43%), Gaps = 28/250 (11%) Query: 4 ASARPAALLPDHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALT 63 ASAR +A + +Y M + RL + EM G M V GQEAVS G AL Sbjct: 10 ASARISA--EEARMLYEDMVLGRLFEDKCAEMYYKGKMFGFVHLYNGQEAVSTGVIKALK 67 Query: 64 EGDLVLASRRAHALHVGVDLPLGPMIAELIGQDSTCDHAD----QLNSPERSG------A 113 D V ++ R H + +P ++AEL G+ + C L S E + Sbjct: 68 PTDYVCSTYRDHVHALSTGIPPRAVMAELFGKATGCSKGRGGSMHLFSAEHNFLGGYAFV 127 Query: 114 ADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXX 173 A+ P+ A G A+S +D+VT+C G N+G F + NMA LW LP Sbjct: 128 AEGIPV-ATGAAFSAKYRGTDQVTVCFFGDGACNNGQFYECLNMAALWKLPIVYVVENNF 186 Query: 174 XXXXXXRLRGA---------PGHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAG 224 R P G +P VDG DV AVR A+ RARAG G Sbjct: 187 WAIGMAHKRATSVTDIYLKGPAFG------MPGYQVDGMDVLAVREAAQQAIARARAGEG 240 Query: 225 PTVVRAITYR 234 PT++ ITYR Sbjct: 241 PTLLECITYR 250 >tr|C2W8P8|C2W8P8_BACCE Tax_Id=526986 SubName: Full=Pyruvate dehydrogenase, TPP-dependent E1 component alpha-subunit;[Bacillus cereus Rock3-44] Length = 332 Score = 94.4 bits (233), Expect = 2e-17 Identities = 83/310 (26%), Positives = 131/310 (42%), Gaps = 34/310 (10%) Query: 18 MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHAL 77 MY +M +R + + E+ A G++ V G+EAV++G A LT+ D + ++ R H Sbjct: 20 MYEKMLEIRKFEDKVHELFAQGVLPGFVHLYAGEEAVAVGVCAHLTDSDSITSTHRGHGH 79 Query: 78 HVGVDLPLGPMIAELIGQ-DSTCD------HADQLNSP--ERSGAADQCPLLAVGHAYSQ 128 + L M+AEL G+ C H L+ +G LA G A + Sbjct: 80 CIAKGCELDGMMAELFGKATGLCKGKGGSMHIADLDKGMLGANGIVGGGFPLACGSALTA 139 Query: 129 WLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAPGHG 188 + V++C G N G F + N+A +W LP P Sbjct: 140 KYKGTKDVSVCFFGDGANNEGTFHEGVNLAAIWKLPVIFVAENNGYG------EATPFEY 193 Query: 189 GDACQ---------RIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFP 239 +C+ IP V VDG D+ AV + A AV+RAR G GPT++ +TYR ++ Sbjct: 194 ASSCKSIADRAKAYNIPGVRVDGKDLLAVYKAAAEAVERARNGEGPTLIECMTYR--NYG 251 Query: 240 SFDGDYDAAAT----EPFL---DPLV-FTGGRLKAGGADAAQLCDVERTARKLVADAVAL 291 F+G+ T E L D +V F + G +L ++ER + V A+ Sbjct: 252 HFEGEAQTYKTAEEKEEHLNEKDAIVNFRKHLINKGLLTETELVNMERAVDEAVQKAIEF 311 Query: 292 AKSGTCPGHD 301 ++ P + Sbjct: 312 SEKSPYPADE 321 >tr|C1A6D2|C1A6D2_GEMAT Tax_Id=379066 (pdhA)SubName: Full=Pyruvate dehydrogenase E1 component alpha subunit; EC=1.2.4.1;[Gemmatimonas aurantiaca] Length = 347 Score = 94.0 bits (232), Expect = 2e-17 Identities = 82/299 (27%), Positives = 125/299 (41%), Gaps = 19/299 (6%) Query: 15 HLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRA 74 H E+ M + R + EM A G + +GQEAVS G A L D ++ + R Sbjct: 30 HRELLYSMLLQRRFEERCAEMYAIGRIGGFCHLYIGQEAVSTGVIAQLRSDDYIITTYRD 89 Query: 75 HALHVGVDLPLGPMIAELIGQDSTCDHAD---------QLNSPERSGAADQCPLLAVGHA 125 H + + +++EL G+ C QL G +A G Sbjct: 90 HGQALARGMTPRAVMSELFGRQDGCAKGKGGSMHMFDKQLGFLGGHGIVGGHVPMAAGVG 149 Query: 126 YSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAP 185 ++ D+V C G VN+GAF +A NMA LW LP R + Sbjct: 150 FAIKYRGGDQVIACFMGESVVNTGAFHEALNMAALWKLPCVFIIENNRYGMGTALERASS 209 Query: 186 GHG---GDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFD 242 H A +P VDG DV AVR+ +A +++RAR + PT++ TYR D Sbjct: 210 IHDIYKRGASYDMPRDVVDGQDVLAVRKAMAESIERARKESMPTLLEIRTYRFMGHSMSD 269 Query: 243 GDYDAAATEPFL------DPLVFTGGRLK-AGGADAAQLCDVERTARKLVADAVALAKS 294 T+ L DP+V R++ AG A ++ ++ +KLV D++ A++ Sbjct: 270 AVSGTYRTKEELEQYLKRDPIVLHRQRMEDAGEITADEITAMDEEIKKLVQDSIDFAEA 328 >tr|C5PMC1|C5PMC1_9SPHI Tax_Id=525373 (pdhA)SubName: Full=Pyruvate dehydrogenase; EC=1.2.4.1;[Sphingobacterium spiritivorum ATCC 33861] Length = 331 Score = 94.0 bits (232), Expect = 2e-17 Identities = 88/306 (28%), Positives = 127/306 (41%), Gaps = 27/306 (8%) Query: 15 HLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRA 74 +LE Y+ M ++R + ++ + +GQEAV G + + D ++ + R Sbjct: 11 YLEWYKSMLLMRKFEEKAGQLYGQQKIRGFCHLYIGQEAVVAGTMSVIGPEDSLITAYRD 70 Query: 75 HALHVGVDLPLGPMIAELIGQDSTCD-------HADQLNSPERSG---AADQCPLLAVGH 124 HA + + +AEL G+ + C H G Q PL A G Sbjct: 71 HAHALAKGVSADACMAELYGKATGCSKGKGGSMHFFSKEHKFMGGHGIVGGQIPLGA-GI 129 Query: 125 AYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGA 184 A+++ + + V +C G V GAF + NMA+LW LP R Sbjct: 130 AFAEMYNGTKNVNVCYMGDGAVRQGAFNETLNMAMLWKLPVIFVCENNGYAMGTSVQRTT 189 Query: 185 P-------GHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR--- 234 GHG D +PS VDG DV AV + AVQRARAG GPT + TYR Sbjct: 190 NMIDIYKMGHGFD----MPSAAVDGMDVVAVHNAMDEAVQRARAGEGPTFLEIRTYRYKG 245 Query: 235 -SSDFPSFDGDYDAAATEPFLDPLVFT-GGRLKAGGADAAQLCDVERTARKLVADAVALA 292 S P+ + DPL+ T L+ AD A +VE +K+V D+V A Sbjct: 246 HSMSDPAKYRTKEELEEYKGRDPLLSTKHAILENKYADDAWFAEVEADVKKVVEDSVKFA 305 Query: 293 KSGTCP 298 + P Sbjct: 306 EESPYP 311 >tr|C2G077|C2G077_9SPHI Tax_Id=525372 (pdhA)SubName: Full=Pyruvate dehydrogenase; EC=1.2.4.1;[Sphingobacterium spiritivorum ATCC 33300] Length = 331 Score = 94.0 bits (232), Expect = 2e-17 Identities = 88/306 (28%), Positives = 127/306 (41%), Gaps = 27/306 (8%) Query: 15 HLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRA 74 +LE Y+ M ++R + ++ + +GQEAV G + + D ++ + R Sbjct: 11 YLEWYKSMLLMRKFEEKAGQLYGQQKIRGFCHLYIGQEAVVAGTMSVIGPEDSLITAYRD 70 Query: 75 HALHVGVDLPLGPMIAELIGQDSTCD-------HADQLNSPERSG---AADQCPLLAVGH 124 HA + + +AEL G+ + C H G Q PL A G Sbjct: 71 HAHALAKGVSADACMAELYGKATGCSKGKGGSMHFFSKEHKFMGGHGIVGGQIPLGA-GI 129 Query: 125 AYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGA 184 A+++ + + V +C G V GAF + NMA+LW LP R Sbjct: 130 AFAEMYNGTKNVNVCYMGDGAVRQGAFNETLNMAMLWKLPVIFVCENNGYAMGTSVQRTT 189 Query: 185 P-------GHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR--- 234 GHG D +PS VDG DV AV + AVQRARAG GPT + TYR Sbjct: 190 NMIDIYKMGHGFD----MPSAAVDGMDVVAVHNAMDEAVQRARAGEGPTFLEIRTYRYKG 245 Query: 235 -SSDFPSFDGDYDAAATEPFLDPLVFT-GGRLKAGGADAAQLCDVERTARKLVADAVALA 292 S P+ + DPL+ T L+ AD A +VE +K+V D+V A Sbjct: 246 HSMSDPAKYRTKEELEEYKGRDPLLSTKHAILENKYADDAWFAEVEADVKKVVEDSVKFA 305 Query: 293 KSGTCP 298 + P Sbjct: 306 EESPYP 311 >tr|A4YG22|A4YG22_METS5 Tax_Id=399549 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring); EC=1.2.4.1;[Metallosphaera sedula] Length = 344 Score = 94.0 bits (232), Expect = 2e-17 Identities = 83/307 (27%), Positives = 125/307 (40%), Gaps = 24/307 (7%) Query: 16 LEMYRRMWVLRLLDMALEEM---------RADGLMESPVSTALGQEAVSIGATAALTEGD 66 L MY +M ++R + A+ A G + + + GQEAV++G L + D Sbjct: 27 LNMYYQMNLIREFEEAIGAKYYEGKNPFNMASGPIRGEMHLSSGQEAVAVGVGGNLRKED 86 Query: 67 LVLASRRAHALHVGVDLPLGPMIAELIGQDSTC-----DHADQLNSPER---SGAADQCP 118 +V+++ R H + + + AE+ G+ + H + R SG Sbjct: 87 VVVSTHRPHHHAIAKGTDIRKLAAEIFGKSTGLCGGKGGHMHLFDKEVRFSCSGIVGASF 146 Query: 119 LLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXX 178 A G A++ D V + G N G F + N A LW LP Sbjct: 147 PQAAGAAFAFKYRGEDNVAVAFAGEGAANHGTFYETLNAASLWELPLIVVIEDNMYADST 206 Query: 179 XR--LRGAPGHGGDACQ-RIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRS 235 + P H A +PS VDG DV V AVQRAR+G GP+++ A+TYR Sbjct: 207 PKSVALATPHHFQRAMSLNVPSFLVDGMDVIDVYLATRKAVQRARSGGGPSLIEAVTYRF 266 Query: 236 SDFPSFDG----DYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVAL 291 DG + D +DP+ G RL G + +L + R AR+ V DA+ Sbjct: 267 RGHFEGDGQEYRERDEVELWRVMDPITRLGNRLTKLGVEKERLENERRKARERVEDALKF 326 Query: 292 AKSGTCP 298 A+ P Sbjct: 327 AEESPYP 333 >tr|Q2JPJ0|Q2JPJ0_SYNJB Tax_Id=321332 SubName: Full=Dehydrogenase E1 component, alpha subunit;[Synechococcus sp.] Length = 333 Score = 93.6 bits (231), Expect = 3e-17 Identities = 75/230 (32%), Positives = 99/230 (43%), Gaps = 14/230 (6%) Query: 18 MYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHAL 77 +Y M + RL + EM G M V GQEAVS G AL D V ++ R H Sbjct: 22 LYEDMVLGRLFEDKCAEMYYKGKMFGFVHLYNGQEAVSTGVIKALKPTDYVCSTYRDHVH 81 Query: 78 HVGVDLPLGPMIAELIGQDSTCDHAD----QLNSPERSG------AADQCPLLAVGHAYS 127 + +P ++AEL G+ + C L S E + A+ P+ A G A+S Sbjct: 82 ALSTGIPPRAVMAELFGKATGCSKGRGGSMHLFSAEHNFLGGYAFVAEGIPV-ATGAAFS 140 Query: 128 QWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAPG- 186 +D+VT C G N+G F + NMA LW LP R Sbjct: 141 AKYRGTDQVTACFFGDGACNNGQFYECLNMAALWKLPIIYVVENNFWAIGMAHERATSDT 200 Query: 187 --HGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR 234 + +P VDG DV AVR A+ RARAG GPT++ ITYR Sbjct: 201 DIYRKGPAFGMPGYQVDGMDVLAVREAAQQAIARARAGEGPTLLECITYR 250 >tr|A0ZHY4|A0ZHY4_NODSP Tax_Id=313624 SubName: Full=Dehydrogenase, E1 component;[Nodularia spumigena CCY9414] Length = 344 Score = 93.2 bits (230), Expect = 3e-17 Identities = 90/308 (29%), Positives = 130/308 (42%), Gaps = 25/308 (8%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEG-DLVLASRRA 74 L +Y M + R + EM G M V GQEAVS G A+ G D V ++ R Sbjct: 23 LRLYEDMVLGRSFEDKCAEMYYRGKMFGFVHLYNGQEAVSTGVIQAMRPGEDFVSSTYRD 82 Query: 75 HALHVGVDLPLGPMIAELIGQDSTCDHAD----QLNSPER------SGAADQCPLLAVGH 124 H + +P ++AEL G+ + C + S E + A+ P+ A Sbjct: 83 HVHALSAGVPAREVMAELFGKATGCSKGRGGSMHMFSAEHGLLGGYAFVAEGIPVAAGAA 142 Query: 125 AYSQWL------DNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXX 178 S++ N+D+VT C G N+G F + NMA LW LP Sbjct: 143 FQSKYRREVLKDQNADQVTACFFGDGAANNGQFFETLNMASLWKLPIIFVVENNKWAIGM 202 Query: 179 XRLRGAPG---HGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRS 235 R + + + V VDG DV AVR AV RARAG GPT++ A+TYR Sbjct: 203 SHERATSQPEIYKKASVFNMVGVEVDGMDVLAVRAVAQEAVARARAGEGPTLIEALTYRF 262 Query: 236 SDFPSFDGDYDAAATEPFL----DPL-VFTGGRLKAGGADAAQLCDVERTARKLVADAVA 290 D D + E DP+ L+ AD A+L ++R ++++ +AV Sbjct: 263 RGHSLADPDEMRSKAEKEFWFSRDPIKKLAAYLLEQNLADDAELKAIDRKIQEVIDEAVK 322 Query: 291 LAKSGTCP 298 A+S P Sbjct: 323 FAESSPEP 330 >tr|Q0MX87|Q0MX87_9BACT Tax_Id=397422 SubName: Full=Acetoin dehydrogenase alpha-subunit;[consortium cosmid clone pGZ1] Length = 344 Score = 92.8 bits (229), Expect = 4e-17 Identities = 89/314 (28%), Positives = 129/314 (41%), Gaps = 34/314 (10%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGL------------MESPVSTALGQEAVSIGATAALT 63 L++YR M +R + A E G+ + P+ + GQEAV+ G + L Sbjct: 15 LDLYRTMCRIRAFEDAALEASRGGVTAFGQSAGTRAQVRGPLHLSTGQEAVATGVCSQLR 74 Query: 64 EGDLVLASRRAHALHVGVDLPLGPMIAELIGQDS--------TCDHAD-QLNSPERSGAA 114 D + ++ R H + L M+ EL G+ S + AD + +G Sbjct: 75 ADDWLTSTHRGHGHTIAKGADLRRMMHELFGRASGFCGGKGGSMHIADFSVGMLGANGVV 134 Query: 115 DQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXX 174 +AVG A S + D + +C G +N G F + N A + LP Sbjct: 135 AAGIPIAVGAAQSMRVQGRDSIAVCFFGDGALNRGPFGEGLNWAAAFRLPMLFVCEDNQW 194 Query: 175 XXXXXRLRGAPGHGGDACQR---IPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAI 231 + G G A R +P++ VDG DV AV R AV RAG GP ++ A Sbjct: 195 SATTRTAEMSAGDGAAARARGFGVPALEVDGMDVVAVWRAARDAVASVRAGEGPRLLHAK 254 Query: 232 TYRSSDFPSFD-------GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKL 284 TYR + S D G+ AA + DPL+ RL+A G + R AR+ Sbjct: 255 TYRFTGHVSVDPAAYRDPGELAAAMED---DPLLVARVRLQASGVAGDAVEAAMRAAREE 311 Query: 285 VADAVALAKSGTCP 298 VA AVA A + P Sbjct: 312 VAAAVASADAAEWP 325 >tr|B7R8L3|B7R8L3_9THEO Tax_Id=391606 (pdhA_2)SubName: Full=Pyruvate dehydrogenase E1 component, alpha subunit; EC=1.2.4.1;[Carboxydibrachium pacificum DSM 12653] Length = 328 Score = 92.8 bits (229), Expect = 4e-17 Identities = 91/308 (29%), Positives = 133/308 (43%), Gaps = 33/308 (10%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAH 75 L+MY RM +R + + E+ A G + V +G+EAV++G L E D + ++ R H Sbjct: 9 LDMYTRMVKIRKFEERVAELFAQGKVLGFVHLYIGEEAVAVGVCENLKEEDYITSTHRGH 68 Query: 76 ALHVGVDLPLGPMIAELIGQDS--------TCDHADQLNSP-ERSGAADQCPLLAVGHAY 126 + L M+AEL G+++ + AD +G +A G A Sbjct: 69 GHLIAKGGDLKYMMAELFGKETGYCKGKGGSMHIADATKGILGANGIVGGGFPIAAGAAL 128 Query: 127 SQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRG--- 183 S + +D+V +C G N F +A N+A +W LP + R Sbjct: 129 SAKMRGTDQVAVCFFGDGASNQATFHEALNIASIWKLPVVFVCENNLYGISMRQDRHQAI 188 Query: 184 ------APGHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSD 237 A G+G IP VTVDG+DV AV A+ RAR GAGPT+V TYR Sbjct: 189 KDIADRAVGYG------IPGVTVDGNDVLAVYEVAKEAINRARNGAGPTLVECKTYRYRG 242 Query: 238 FPSFDGD----YDAAATEPFL--DPLV-FTGGRLKAGGADAAQLCDVERTARKLVADAVA 290 F+GD E +L DP++ T L A +L D+E + V +AV Sbjct: 243 --HFEGDPTVYRPKEEVEEWLAKDPILRLTRYILDNDIASEKELKDIEAKIIEEVEEAVK 300 Query: 291 LAKSGTCP 298 A+ P Sbjct: 301 FAEESPYP 308 >tr|A4AIF8|A4AIF8_9ACTN Tax_Id=312284 SubName: Full=Acetoin dehydrogenase (TPP-dependent) alpha chain;[marine actinobacterium PHSC20C1] Length = 327 Score = 92.8 bits (229), Expect = 4e-17 Identities = 83/296 (28%), Positives = 123/296 (41%), Gaps = 29/296 (9%) Query: 22 MWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHALHVGV 81 MW +R + A+E++ GLM + ++GQEAV GA AL D + ++ R H + Sbjct: 22 MWKIRRFEEAVEDLYGRGLMHGTMHLSIGQEAVPTGACLALNRDDYITSTHRGHGHCIAK 81 Query: 82 DLPLGPMIAELI--------GQDSTCDHAD-QLNSPERSGAADQCPLLAVGHAYSQWLDN 132 + M+AEL+ G+ + AD + + +G +A G A S + Sbjct: 82 GADMERMMAELLAKETGYCRGRGGSMHIADTETGNLGANGIVAGGVPIATGAALSAKMRG 141 Query: 133 SDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRG--------- 183 + +V + G + GA+ + +A +W LP + Sbjct: 142 TKQVAVSFHGDGAMGEGAWHEGVVLAAMWQLPVVFLCENNLYGMSMSSEKAFNLEKLSDR 201 Query: 184 APGHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFDG 243 A G+G IP VTVDG+DVQAV AV RAR G GPT + A TYR D Sbjct: 202 ARGYG------IPGVTVDGNDVQAVYDATQEAVDRARNGGGPTFIEAKTYRWRGHSKSDK 255 Query: 244 DYDAAATE----PFLDPL-VFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKS 294 + E DP+ +F L AGG A + V R + AV A + Sbjct: 256 NLYRTRDEIDEWRGKDPIPLFEAQALAAGGLTQADIDAVRDKVRTELRSAVQRANA 311 >tr|B9LFA5|B9LFA5_CHLSY Tax_Id=480224 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring); EC=1.2.4.1;[Chloroflexus aurantiacus] Length = 338 Score = 92.0 bits (227), Expect = 8e-17 Identities = 86/299 (28%), Positives = 125/299 (41%), Gaps = 21/299 (7%) Query: 19 YRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHALH 78 Y RM ++R + L A G + V G+EAV++G A L + D + ++ R H Sbjct: 12 YERMRLIREFEDRLHTDFAAGKIPGFVHLYAGEEAVAVGLCAHLRDDDFITSTHRGHGHC 71 Query: 79 VGVDLPLGPMIAELIGQDS-TCD------HADQLNSPE--RSGAADQCPLLAVGHAYSQW 129 + + L M+AE+ G+ + C H ++ +G P LA G + Sbjct: 72 IAKGVDLRAMMAEIYGKATGACKGKGGSMHIADVDKGMLGANGIVGGGPPLACGAGLTAK 131 Query: 130 LDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAPGHGG 189 + +D+VT+C G N G + N+A +W LP G Sbjct: 132 IKGTDQVTVCFFGDGASNQGTTFEGLNLAGIWKLPVVFVCENNGYAETTSPRYSVSGQDI 191 Query: 190 DACQR---IPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFDGD-- 244 A R +PS+ +DG D AV AV RAR G GPT + A TYR + F+GD Sbjct: 192 AARARGFGMPSIAIDGLDFFAVYEAAGEAVARARRGEGPTFIEAQTYRY--YGHFEGDSI 249 Query: 245 ----YDAAATEPFLDPLVFTGGRLKAGG-ADAAQLCDVERTARKLVADAVALAKSGTCP 298 D A LD L + A G AA+L +++ AR V DAV A P Sbjct: 250 RYRTRDEEAHYRSLDCLHRFRQTVTAQGLLTAAELDEIDARARAAVEDAVRFAAESPLP 308 >tr|B0SQK8|B0SQK8_LEPBP Tax_Id=456481 (acoA)SubName: Full=Pyruvate dehydrogenase E1 alpha subunit; EC=1.2.4.1;[Leptospira biflexa serovar Patoc] Length = 322 Score = 92.0 bits (227), Expect = 8e-17 Identities = 79/300 (26%), Positives = 126/300 (42%), Gaps = 26/300 (8%) Query: 17 EMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHA 76 E YR+M ++R + A + + G + + +GQEAV +G+ AALT D ++++ R H Sbjct: 17 EFYRQMVLIRKFEEAAAKAYSVGKIGGFLHLYIGQEAVGVGSIAALTPHDYIVSTYRDHG 76 Query: 77 LHVGVDLPLGPMIAELIGQDSTCD-------HADQLNSPERSGAADQCPLLAVGHAYSQW 129 + L P++AEL G+ + H N+ G LA G A++ Sbjct: 77 HALARGLHPNPLMAELFGKATGISKGNGGSMHFFDKNAHFMGGHIS----LAAGIAFASK 132 Query: 130 LDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAP---- 185 D VT+C G N G+F + N+A +W LP R Sbjct: 133 YKKEDSVTICFFGEGAANIGSFHEGLNLAAIWKLPVVFICENNHYAMGTPEYRALAVKDV 192 Query: 186 ---GHGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR----SSDF 238 H D + ++G +V+ VR V AV+RAR G GPT++ TYR S Sbjct: 193 SIRAHAYDMARD----HIEGDEVRKVRDHVKVAVERARRGEGPTLIEVSTYRFRGHSMSD 248 Query: 239 PSFDGDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTARKLVADAVALAKSGTCP 298 P+ + DPL+ L+ GG +L +E + + +A A++ P Sbjct: 249 PAKYRTKEELEAYKKKDPLMRARHELELGGIKPNELDKLETDIQTQIDEAYQFAETSPEP 308 >tr|A9WB62|A9WB62_CHLAA Tax_Id=324602 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring); EC=1.2.4.1;[Chloroflexus aurantiacus] Length = 338 Score = 92.0 bits (227), Expect = 8e-17 Identities = 86/299 (28%), Positives = 125/299 (41%), Gaps = 21/299 (7%) Query: 19 YRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAHALH 78 Y RM ++R + L A G + V G+EAV++G A L + D + ++ R H Sbjct: 12 YERMRLIREFEDRLHTDFAAGKIPGFVHLYAGEEAVAVGLCAHLRDDDFITSTHRGHGHC 71 Query: 79 VGVDLPLGPMIAELIGQDS-TCD------HADQLNSPE--RSGAADQCPLLAVGHAYSQW 129 + + L M+AE+ G+ + C H ++ +G P LA G + Sbjct: 72 IAKGVDLRAMMAEIYGKATGACKGKGGSMHIADVDKGMLGANGIVGGGPPLACGAGLTAK 131 Query: 130 LDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLRGAPGHGG 189 + +D+VT+C G N G + N+A +W LP G Sbjct: 132 IKGTDQVTVCFFGDGASNQGTTFEGLNLAGIWKLPVVFVCENNGYAETTSPRYSVSGQDI 191 Query: 190 DACQR---IPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRSSDFPSFDGD-- 244 A R +PS+ +DG D AV AV RAR G GPT + A TYR + F+GD Sbjct: 192 AARARGFGMPSIAIDGLDFFAVYEAAGEAVARARRGEGPTFIEAQTYRY--YGHFEGDSI 249 Query: 245 ----YDAAATEPFLDPLVFTGGRLKAGG-ADAAQLCDVERTARKLVADAVALAKSGTCP 298 D A LD L + A G AA+L +++ AR V DAV A P Sbjct: 250 RYRTRDEEAHYRSLDCLHRFRQTVTAQGLLTAAELDEIDARARAAVEDAVRFAAESPLP 308 >tr|C4WR55|C4WR55_9RHIZ Tax_Id=641118 SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring);[Ochrobactrum intermedium LMG 3301] Length = 345 Score = 92.0 bits (227), Expect = 8e-17 Identities = 80/305 (26%), Positives = 133/305 (43%), Gaps = 19/305 (6%) Query: 13 PDHL-EMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLAS 71 PD L E +M+++R + EE GL+ + ++GQEA ++G+ L + D++ ++ Sbjct: 27 PDQLKEALHKMYLIRRFEEGAEESYTRGLIHGTMHLSIGQEASAMGSCLPLNDDDMITST 86 Query: 72 RRAHALHVGVDLPLGPMIAELIGQDS--------TCDHAD-QLNSPERSGAADQCPLLAV 122 R H + + M AE G+++ + AD + +G +AV Sbjct: 87 HRGHGHCIAKGADVKRMFAEFFGKETGYCKGRGGSMHIADVSKGNLGANGIVGGGIPIAV 146 Query: 123 GHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXXXRLR 182 G A S + +V + G N GAF +A NMA +W LP R Sbjct: 147 GAALSAKKQKNGKVVVSFFGDGANNEGAFHEALNMASVWKLPVVFVCENNGYGMSTSTRR 206 Query: 183 G-APGHGGD--ACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYR----- 234 A + D + +P V VDG+++ V V+ A +RAR G GPT++ TYR Sbjct: 207 STAVANVADRASAYNMPGVIVDGNNLSEVAEAVSEATERARRGDGPTLIENKTYRIRGHS 266 Query: 235 SSDFPSFDGDYDAAATEPFLDPLVFTGGRLKA-GGADAAQLCDVERTARKLVADAVALAK 293 SD + + + DP+ LKA G + A++ + K +A+A+ AK Sbjct: 267 KSDRNRYRTKEEIEHWQNDRDPIAHFEADLKAYGFINDAEIEAIRAEVEKEIAEAIEFAK 326 Query: 294 SGTCP 298 + P Sbjct: 327 NSPAP 331 >tr|A8TJR3|A8TJR3_9PROT Tax_Id=331869 SubName: Full=Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit;[alpha proteobacterium BAL199] Length = 334 Score = 92.0 bits (227), Expect = 8e-17 Identities = 79/316 (25%), Positives = 130/316 (41%), Gaps = 28/316 (8%) Query: 8 PAALLPDHLEM------YRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAA 61 PA +P +L++ +R MW +R + A + + L+ + ++GQE +++G + Sbjct: 2 PATSVPRNLDVDRLLSHHRLMWRIRAFEEAALQANTEKLVLGAIHPSIGQEGIAVGVCSN 61 Query: 62 LTEGDLVLASRRAHALHVGVDLPLGPMIAELIGQDSTCDHAD---------QLNSPERSG 112 L D++ ++ R H + G M+ EL+G++ H + +G Sbjct: 62 LNRDDILSSTHRGHGHTLAKGADAGAMMRELLGREGGTSHGKGGSMHIADFTVGMLGANG 121 Query: 113 AADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLP--XXXXXX 170 + G A++ L +RV I G +N G F++ N A ++ LP Sbjct: 122 VVAANIHITAGAAHAIKLRGENRVACSIFGDGAINRGPFLEGLNWAKVFELPALFVCEDN 181 Query: 171 XXXXXXXXXRLRGAPGHGGDA-CQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVR 229 + G PG A +P+V VDG+DV AV AV RAG GP + Sbjct: 182 GFASTTRTAAMTGGPGPAARAEALGVPAVEVDGNDVLAVDEATREAVVAIRAGGGPRFIV 241 Query: 230 AITYRSSDFPSFD-------GDYDAAATEPFLDPLVFTGGRLKAGGADAAQLCDVERTAR 282 A TYR + + D + DAA + DP+ L G L + ER A+ Sbjct: 242 AKTYRLTGHTASDPAAYRPKDEVDAAWRD---DPIARLAQTLADAGVKGMTLAENERVAK 298 Query: 283 KLVADAVALAKSGTCP 298 + A AK+ P Sbjct: 299 DEMDGVYADAKAAPWP 314 >tr|Q5N030|Q5N030_SYNP6 Tax_Id=269084 (pdhA)SubName: Full=Pyruvate dehydrogenase E1 component alpha subunit;[Synechococcus sp.] Length = 342 Score = 91.7 bits (226), Expect = 1e-16 Identities = 89/308 (28%), Positives = 127/308 (41%), Gaps = 26/308 (8%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAH 75 L +Y M + R + EM G M V GQEAV+ G A+ D V ++ R H Sbjct: 23 LRIYEDMVLGRTFEDKCAEMYYRGKMFGFVHLYNGQEAVASGIIKAMRSDDYVCSTYRDH 82 Query: 76 ALHVGVDLPLGPMIAELIGQDSTCDHAD----QLNSPERS------GAADQCPLLAVGHA 125 + +P ++AEL G+++ C L S E + A+ P+ A G A Sbjct: 83 VHALSAGVPARQVMAELFGKETGCSRGRGGSMHLFSAEHNLLGGFAFVAEGIPV-ATGAA 141 Query: 126 YSQWL-------DNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXX 178 ++ ++D+VT C G N+G F + NMA LW LP Sbjct: 142 FTTAYRRNALGDTSADQVTACFFGDGAANNGQFFECLNMATLWKLPILFVVENNKWAIGM 201 Query: 179 XRLRGAPG---HGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRS 235 R + +P V VDG DV AVR A+ RARAG GPT++ A+TYR Sbjct: 202 SHERATSDPEIYKKGPAFGMPGVEVDGMDVLAVRAVAQEAIARARAGEGPTLIEALTYRF 261 Query: 236 SDFPSFDGDYDAAATEPFL----DPLV-FTGGRLKAGGADAAQLCDVERTARKLVADAVA 290 D D + E DP+ F + A +L +++ LVA+AV Sbjct: 262 RGHSLADPDELRSKEEKEFWLARDPIKRFAAHLTEFNLATHEELKAIDKKIEALVAEAVE 321 Query: 291 LAKSGTCP 298 A S P Sbjct: 322 FAISSPEP 329 >tr|Q31LU5|Q31LU5_SYNE7 Tax_Id=1140 SubName: Full=Pyruvate dehydrogenase (Lipoamide); EC=1.2.4.1;[Synechococcus elongatus] Length = 342 Score = 91.7 bits (226), Expect = 1e-16 Identities = 89/308 (28%), Positives = 127/308 (41%), Gaps = 26/308 (8%) Query: 16 LEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIGATAALTEGDLVLASRRAH 75 L +Y M + R + EM G M V GQEAV+ G A+ D V ++ R H Sbjct: 23 LRIYEDMVLGRTFEDKCAEMYYRGKMFGFVHLYNGQEAVASGIIKAMRSDDYVCSTYRDH 82 Query: 76 ALHVGVDLPLGPMIAELIGQDSTCDHAD----QLNSPERS------GAADQCPLLAVGHA 125 + +P ++AEL G+++ C L S E + A+ P+ A G A Sbjct: 83 VHALSAGVPARQVMAELFGKETGCSRGRGGSMHLFSAEHNLLGGFAFVAEGIPV-ATGAA 141 Query: 126 YSQWL-------DNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXXXXXXXXXXXXXX 178 ++ ++D+VT C G N+G F + NMA LW LP Sbjct: 142 FTTAYRRNALGDTSADQVTACFFGDGAANNGQFFECLNMATLWKLPILFVVENNKWAIGM 201 Query: 179 XRLRGAPG---HGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGAGPTVVRAITYRS 235 R + +P V VDG DV AVR A+ RARAG GPT++ A+TYR Sbjct: 202 SHERATSDPEIYKKGPAFGMPGVEVDGMDVLAVRAVAQEAIARARAGEGPTLIEALTYRF 261 Query: 236 SDFPSFDGDYDAAATEPFL----DPLV-FTGGRLKAGGADAAQLCDVERTARKLVADAVA 290 D D + E DP+ F + A +L +++ LVA+AV Sbjct: 262 RGHSLADPDELRSKEEKEFWLARDPIKRFAAHLTEFNLATHEELKAIDKKIEALVAEAVE 321 Query: 291 LAKSGTCP 298 A S P Sbjct: 322 FAISSPEP 329 >tr|Q0APT0|Q0APT0_MARMM Tax_Id=394221 SubName: Full=Dehydrogenase, E1 component;[Maricaulis maris] Length = 346 Score = 91.7 bits (226), Expect = 1e-16 Identities = 89/321 (27%), Positives = 133/321 (41%), Gaps = 28/321 (8%) Query: 4 ASARPAALLP------DHLEMYRRMWVLRLLDMALEEMRADGLMESPVSTALGQEAVSIG 57 A+ +P + P + L+ YR M ++R + ++ GL+ +GQEAV G Sbjct: 15 AAKKPTTVAPGTAGKDELLQYYRDMLMMRRFEEKAGQLYGMGLIAGFCHLYIGQEAVVTG 74 Query: 58 ATAALTEGDLVLASRR--AHALHVGVDLPLGPMIAELIGQDSTCDHAD----QLNSPERS 111 AAL EGD V+ R AH L G+D P G M AEL G++ + S E+ Sbjct: 75 IQAALEEGDQVITGYRDHAHMLACGMD-PKGVM-AELTGREGGYSRGKGGSMHMFSREKQ 132 Query: 112 -----GAADQCPLLAVGHAYSQWLDNSDRVTLCITGPDDVNSGAFVQAANMAVLWHLPXX 166 G L G ++ W + ++++ G N G ++ NMA LW+LP Sbjct: 133 FYGGHGIVGAQVALGTGLGFADWYKGNGKLSVAYFGDGAANQGQVYESFNMAKLWNLPVI 192 Query: 167 XXXXXXXXXXXXXRLRGAPG---HGGDACQRIPSVTVDGHDVQAVRRCVATAVQRARAGA 223 R + H IP VDG DV+AV+R AV+ AR G Sbjct: 193 YVIENNQYAMGTSVKRASSETALHKRGISFGIPGEEVDGMDVEAVKRAAEKAVKHARGGN 252 Query: 224 GPTVVRAITYR-----SSDFPSFDGDYDAAATEPFLDPLVFTGGRLKAGG-ADAAQLCDV 277 GP ++ TYR SD + + DP+ RL GG A +L + Sbjct: 253 GPYILEMKTYRYRGHSMSDPAKYRTREEVDDIRSHHDPIDLIKKRLVEGGHATEDELKAL 312 Query: 278 ERTARKLVADAVALAKSGTCP 298 ++ + +V +A AK P Sbjct: 313 DKDVKAIVNEAAQFAKDSPEP 333 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.319 0.133 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 2,218,177,715 Number of extensions: 85668765 Number of successful extensions: 199285 Number of sequences better than 10.0: 2266 Number of HSP's gapped: 197989 Number of HSP's successfully gapped: 2614 Length of query: 304 Length of database: 3,846,993,858 Length adjustment: 137 Effective length of query: 167 Effective length of database: 2,302,291,047 Effective search space: 384482604849 Effective search space used: 384482604849 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 80 (35.4 bits)