BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_5021 (347 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|B2HI25|HOA2_MYCMM Tax_Id=216594 RecName: Full=4-hydroxy-2-oxo... 658 0.0 sp|A0PUX2|HOA2_MYCUA Tax_Id=362242 RecName: Full=4-hydroxy-2-oxo... 653 0.0 sp|P71867|HOA_MYCTU Tax_Id=1773 RecName: Full=4-hydroxy-2-oxoval... 619 e-175 sp|A5U8K8|HOA_MYCTA Tax_Id=419947 (bphI)RecName: Full=4-hydroxy-... 619 e-175 sp|C1AHZ2|HOA_MYCBT Tax_Id=561275 RecName: Full=4-hydroxy-2-oxov... 619 e-175 sp|A1KPL9|HOA_MYCBP Tax_Id=410289 RecName: Full=4-hydroxy-2-oxov... 619 e-175 sp|Q7TW97|HOA_MYCBO Tax_Id=1765 RecName: Full=4-hydroxy-2-oxoval... 619 e-175 tr|C6DM51|C6DM51_MYCTK Tax_Id=478434 SubName: Full=4-hydroxy-2-o... 619 e-175 tr|A5WTA3|A5WTA3_MYCTF Tax_Id=336982 SubName: Full=Hypothetical ... 619 e-175 tr|A2VPU6|A2VPU6_MYCTU Tax_Id=348776 SubName: Full=Putative unch... 619 e-175 sp|Q743Q8|HOA_MYCPA Tax_Id=1770 RecName: Full=4-hydroxy-2-oxoval... 618 e-175 sp|Q1B2X1|HOA1_MYCSS Tax_Id=164756 RecName: Full=4-hydroxy-2-oxo... 617 e-175 sp|A1UM80|HOA1_MYCSK Tax_Id=189918 RecName: Full=4-hydroxy-2-oxo... 617 e-175 tr|A4KM21|A4KM21_MYCTU Tax_Id=395095 SubName: Full=Hypothetical ... 617 e-175 sp|A0QAG9|HOA_MYCA1 Tax_Id=243243 RecName: Full=4-hydroxy-2-oxov... 617 e-175 sp|A3Q6M9|HOA2_MYCSJ Tax_Id=164757 RecName: Full=4-hydroxy-2-oxo... 617 e-175 sp|A4T7U4|HOA_MYCGI Tax_Id=350054 RecName: Full=4-hydroxy-2-oxov... 614 e-174 sp|A3Q4B9|HOA1_MYCSJ Tax_Id=164757 RecName: Full=4-hydroxy-2-oxo... 613 e-173 sp|A1TFQ5|HOA3_MYCVP Tax_Id=350058 RecName: Full=4-hydroxy-2-oxo... 612 e-173 sp|A0R4S6|HOA2_MYCS2 Tax_Id=246196 RecName: Full=4-hydroxy-2-oxo... 607 e-172 sp|B1MH40|HOA1_MYCA9 Tax_Id=561007 RecName: Full=4-hydroxy-2-oxo... 592 e-167 tr|C6GCU5|C6GCU5_9NOCA Tax_Id=1830 (hsaF)SubName: Full=HsaF;[Rho... 551 e-155 sp|Q0S815|HOA3_RHOSR Tax_Id=101510 (hsaF)RecName: Full=4-hydroxy... 545 e-153 sp|C0ZPX1|HOA1_RHOE4 Tax_Id=234621 RecName: Full=4-hydroxy-2-oxo... 543 e-152 sp|C1BAJ4|HOA3_RHOOB Tax_Id=632772 RecName: Full=4-hydroxy-2-oxo... 542 e-152 tr|C3JUT2|C3JUT2_RHOER Tax_Id=596309 (dmpG)SubName: Full=4-hydro... 540 e-152 sp|Q5Z2N2|HOA1_NOCFA Tax_Id=37329 RecName: Full=4-hydroxy-2-oxov... 537 e-151 tr|C5II23|C5II23_9NOCA Tax_Id=646677 SubName: Full=4-hydroxy-2-o... 528 e-148 tr|D0L3M4|D0L3M4_GORB4 Tax_Id=526226 SubName: Full=4-hydroxy-2-o... 517 e-145 tr|D1AB65|D1AB65_THECU Tax_Id=471852 SubName: Full=4-hydroxy-2-o... 504 e-141 sp|C1AYB4|HOA5_RHOOB Tax_Id=632772 RecName: Full=4-hydroxy-2-oxo... 488 e-136 sp|Q0S4F8|HOA4_RHOSR Tax_Id=101510 RecName: Full=4-hydroxy-2-oxo... 487 e-135 tr|C2AK53|C2AK53_TSUPA Tax_Id=521096 SubName: Full=4-hydroxy-2-o... 422 e-116 tr|D1A3K8|D1A3K8_THECU Tax_Id=471852 SubName: Full=4-hydroxy-2-o... 410 e-112 tr|C8XHR8|C8XHR8_NAKMY Tax_Id=479431 SubName: Full=4-hydroxy-2-o... 396 e-108 sp|Q0RXC3|HOA6_RHOSR Tax_Id=101510 RecName: Full=4-hydroxy-2-oxo... 387 e-106 sp|B9LCM1|HOA_CHLSY Tax_Id=480224 RecName: Full=4-hydroxy-2-oxov... 361 6e-98 sp|A9W9U3|HOA_CHLAA Tax_Id=324602 RecName: Full=4-hydroxy-2-oxov... 361 6e-98 sp|B9L2J0|HOA_THERP Tax_Id=309801 RecName: Full=4-hydroxy-2-oxov... 360 1e-97 sp|B8GBV5|HOA_CHLAD Tax_Id=326427 RecName: Full=4-hydroxy-2-oxov... 358 4e-97 tr|C6KWI8|C6KWI8_9BACT Tax_Id=77133 SubName: Full=4-hydroxy 2-ox... 349 3e-94 sp|A5UWE6|HOA_ROSS1 Tax_Id=357808 RecName: Full=4-hydroxy-2-oxov... 345 4e-93 tr|C6L0Y8|C6L0Y8_9BACT Tax_Id=77133 SubName: Full=4-hydroxy-2-ox... 345 5e-93 sp|B0VXM7|HOA_BACST Tax_Id=1422 (pheE)RecName: Full=4-hydroxy-2-... 343 1e-92 sp|Q9ZI56|HOA_PSEST Tax_Id=316 (nahM)RecName: Full=4-hydroxy-2-o... 343 2e-92 tr|Q49KG7|Q49KG7_PSEPU Tax_Id=303 (nahM)SubName: Full=NahM;[Pseu... 343 2e-92 sp|Q764S0|HOA_BACPJ Tax_Id=209076 (nahM)RecName: Full=4-hydroxy-... 343 2e-92 tr|Q6WE18|Q6WE18_PSEPU Tax_Id=303 (nahM)SubName: Full=2-oxo-4-hy... 342 3e-92 tr|C8CEC4|C8CEC4_PSEAE Tax_Id=287 (nahM)SubName: Full=2-oxo-4-hy... 342 3e-92 tr|Q84I97|Q84I97_9PSED Tax_Id=115714 (xylK)SubName: Full=2-oxo-4... 342 4e-92 >sp|B2HI25|HOA2_MYCMM Tax_Id=216594 RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;[Mycobacterium marinum] Length = 347 Score = 658 bits (1698), Expect = 0.0 Identities = 337/347 (97%), Positives = 337/347 (97%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL Sbjct: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVASRR 347 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVASRR Sbjct: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVASRR 347 >sp|A0PUX2|HOA2_MYCUA Tax_Id=362242 RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;[Mycobacterium ulcerans] Length = 347 Score = 653 bits (1684), Expect = 0.0 Identities = 335/347 (96%), Positives = 335/347 (96%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKT EQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS Sbjct: 61 GFSKTSEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQH GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHLGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL Sbjct: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVASRR 347 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVASRR Sbjct: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVASRR 347 >sp|P71867|HOA_MYCTU Tax_Id=1773 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium tuberculosis] Length = 346 Score = 619 bits (1595), Expect = e-175 Identities = 315/341 (92%), Positives = 323/341 (94%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL Sbjct: 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+ Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG Sbjct: 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341 >sp|A5U8K8|HOA_MYCTA Tax_Id=419947 (bphI)RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium tuberculosis] Length = 346 Score = 619 bits (1595), Expect = e-175 Identities = 315/341 (92%), Positives = 323/341 (94%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL Sbjct: 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+ Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG Sbjct: 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341 >sp|C1AHZ2|HOA_MYCBT Tax_Id=561275 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium bovis] Length = 346 Score = 619 bits (1595), Expect = e-175 Identities = 315/341 (92%), Positives = 323/341 (94%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL Sbjct: 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+ Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG Sbjct: 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341 >sp|A1KPL9|HOA_MYCBP Tax_Id=410289 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium bovis] Length = 346 Score = 619 bits (1595), Expect = e-175 Identities = 315/341 (92%), Positives = 323/341 (94%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL Sbjct: 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+ Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG Sbjct: 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341 >sp|Q7TW97|HOA_MYCBO Tax_Id=1765 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium bovis] Length = 346 Score = 619 bits (1595), Expect = e-175 Identities = 315/341 (92%), Positives = 323/341 (94%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL Sbjct: 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+ Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG Sbjct: 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341 >tr|C6DM51|C6DM51_MYCTK Tax_Id=478434 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis] Length = 346 Score = 619 bits (1595), Expect = e-175 Identities = 315/341 (92%), Positives = 323/341 (94%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL Sbjct: 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+ Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG Sbjct: 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341 >tr|A5WTA3|A5WTA3_MYCTF Tax_Id=336982 SubName: Full=Hypothetical 4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis] Length = 346 Score = 619 bits (1595), Expect = e-175 Identities = 315/341 (92%), Positives = 323/341 (94%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL Sbjct: 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+ Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG Sbjct: 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341 >tr|A2VPU6|A2VPU6_MYCTU Tax_Id=348776 SubName: Full=Putative uncharacterized protein;[Mycobacterium tuberculosis C] Length = 346 Score = 619 bits (1595), Expect = e-175 Identities = 315/341 (92%), Positives = 323/341 (94%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL Sbjct: 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+ Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG Sbjct: 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341 >sp|Q743Q8|HOA_MYCPA Tax_Id=1770 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium paratuberculosis] Length = 352 Score = 618 bits (1594), Expect = e-175 Identities = 313/343 (91%), Positives = 324/343 (94%) Query: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 IWDVR+TDTSLRDGSHHKRHQF K+EV AIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 10 IWDVRLTDTSLRDGSHHKRHQFTKDEVQAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 69 Query: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 KTPEQELIKLAA+TAK+AKIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 70 KTPEQELIKLAAETAKDAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 129 Query: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRVA Sbjct: 130 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 189 Query: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 ALVAELG+DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 190 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 249 Query: 244 FDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 FDKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 250 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 309 Query: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVASR 346 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG A+R Sbjct: 310 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGAAAAR 352 >sp|Q1B2X1|HOA1_MYCSS Tax_Id=164756 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Mycobacterium sp.] Length = 353 Score = 617 bits (1592), Expect = e-175 Identities = 312/342 (91%), Positives = 323/342 (94%) Query: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 IWDVR+TDTSLRDGSHHKRHQF K+EVGAIVAALD AGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 11 IWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFS 70 Query: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 KTPEQELIKLAA+TAKEAKIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 71 KTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 130 Query: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRVA Sbjct: 131 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 190 Query: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 ALVAELG+DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 191 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250 Query: 244 FDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 FDKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310 Query: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVAS 345 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ+SG A+ Sbjct: 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGATAA 352 >sp|A1UM80|HOA1_MYCSK Tax_Id=189918 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Mycobacterium sp.] Length = 353 Score = 617 bits (1592), Expect = e-175 Identities = 312/342 (91%), Positives = 323/342 (94%) Query: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 IWDVR+TDTSLRDGSHHKRHQF K+EVGAIVAALD AGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 11 IWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFS 70 Query: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 KTPEQELIKLAA+TAKEAKIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 71 KTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 130 Query: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRVA Sbjct: 131 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 190 Query: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 ALVAELG+DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 191 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250 Query: 244 FDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 FDKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310 Query: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVAS 345 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ+SG A+ Sbjct: 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGATAA 352 >tr|A4KM21|A4KM21_MYCTU Tax_Id=395095 SubName: Full=Hypothetical 4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis str. Haarlem] Length = 346 Score = 617 bits (1592), Expect = e-175 Identities = 314/341 (92%), Positives = 323/341 (94%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS Sbjct: 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLARELGLETVGFLMMAHTIAP+KLAAQARIMADAGCQCVYVVDSAGALVLDGVAD Sbjct: 121 IQHFGLARELGLETVGFLMMAHTIAPDKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL Sbjct: 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 IGVFDKIGVKTG EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+ Sbjct: 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG Sbjct: 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341 >sp|A0QAG9|HOA_MYCA1 Tax_Id=243243 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium avium] Length = 352 Score = 617 bits (1590), Expect = e-175 Identities = 312/343 (90%), Positives = 323/343 (94%) Query: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 +WDVR+TDTSLRDGSHHKRHQF K+EV AIVAALD AGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 10 MWDVRLTDTSLRDGSHHKRHQFTKDEVQAIVAALDVAGVPVIEVTHGDGLGGSSFNYGFS 69 Query: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 KTPEQELIKLAA+TAKEAKIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 70 KTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 129 Query: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRVA Sbjct: 130 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 189 Query: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 ALVAELG+DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 190 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 249 Query: 244 FDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 FDKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 250 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 309 Query: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVASR 346 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG A+R Sbjct: 310 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGAAAAR 352 >sp|A3Q6M9|HOA2_MYCSJ Tax_Id=164757 RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;[Mycobacterium sp.] Length = 353 Score = 617 bits (1590), Expect = e-175 Identities = 312/342 (91%), Positives = 322/342 (94%) Query: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 IWDVR+TDTSLRDGSHHKRHQF K+EVGAIVAALD AGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 11 IWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFS 70 Query: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 KTPEQELIKLAA+TAKEAKIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 71 KTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 130 Query: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRVA Sbjct: 131 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 190 Query: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 191 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250 Query: 244 FDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 FDKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310 Query: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVAS 345 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ+SG A+ Sbjct: 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGATAA 352 >sp|A4T7U4|HOA_MYCGI Tax_Id=350054 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium gilvum] Length = 352 Score = 614 bits (1583), Expect = e-174 Identities = 308/337 (91%), Positives = 323/337 (95%) Query: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 IWDVR+TDTSLRDGSHHKRHQF K+EVG+IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 11 IWDVRMTDTSLRDGSHHKRHQFTKDEVGSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 70 Query: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 KTPEQELIKLAA+TAKE+KIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 71 KTPEQELIKLAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 130 Query: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 FGLARELGLETVGFLMM+HTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GVADRV+ Sbjct: 131 FGLARELGLETVGFLMMSHTISPEKLAKQARIMADAGCQCVYVVDSAGALVLEGVADRVS 190 Query: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 ALVAELG+DAQVGFHGHENLGLGVANS+EAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 191 ALVAELGDDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250 Query: 244 FDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 FDKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310 Query: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQES 340 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE+ Sbjct: 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEA 347 >sp|A3Q4B9|HOA1_MYCSJ Tax_Id=164757 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Mycobacterium sp.] Length = 363 Score = 613 bits (1580), Expect = e-173 Identities = 310/337 (91%), Positives = 319/337 (94%) Query: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 IWDVR+TDTSLRDGSHHKRHQF K+EVGAIVAALD AGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 10 IWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFS 69 Query: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 KTPEQELIKLAA+TAKEAKIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 70 KTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 129 Query: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRVA Sbjct: 130 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 189 Query: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 ALVAELG+DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 190 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 249 Query: 244 FDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 FDKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 250 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 309 Query: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQES 340 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKRE ES Sbjct: 310 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREMES 346 >sp|A1TFQ5|HOA3_MYCVP Tax_Id=350058 RecName: Full=4-hydroxy-2-oxovalerate aldolase 3; Short=HOA 3; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 3; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 3;[Mycobacterium vanbaalenii] Length = 350 Score = 612 bits (1577), Expect = e-173 Identities = 309/339 (91%), Positives = 320/339 (94%) Query: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 IWDVR+TDTSLRDGSHHKRHQF K+EV AIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 11 IWDVRMTDTSLRDGSHHKRHQFTKDEVQAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 70 Query: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 KTPEQELIKLAA+TAKE+KIAFLMLPGVGTKEDIKEAQ NGGSICRIATHCTEADVSIQH Sbjct: 71 KTPEQELIKLAAETAKESKIAFLMLPGVGTKEDIKEAQSNGGSICRIATHCTEADVSIQH 130 Query: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GVADRVA Sbjct: 131 FGLARELGLETVGFLMMSHTIPPEKLAKQARIMADAGCQCVYVVDSAGALVLEGVADRVA 190 Query: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 ALVAELG DAQVGFHGHENLGLGVANS+EAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 191 ALVAELGSDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250 Query: 244 FDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 FDKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310 Query: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQ 342 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE+ + Sbjct: 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQETAK 349 >sp|A0R4S6|HOA2_MYCS2 Tax_Id=246196 RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;[Mycobacterium smegmatis] Length = 349 Score = 607 bits (1564), Expect = e-172 Identities = 307/337 (91%), Positives = 318/337 (94%) Query: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 IWDVR+TDTSLRDGSHHKRHQF EEV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 Query: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 KTPEQELIK+AA+TAKE+KIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 Query: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 Query: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 Query: 244 FDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 FDKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 249 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 Query: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQES 340 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE+ Sbjct: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEA 345 >sp|B1MH40|HOA1_MYCA9 Tax_Id=561007 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Mycobacterium abscessus] Length = 359 Score = 592 bits (1526), Expect = e-167 Identities = 299/333 (89%), Positives = 309/333 (92%) Query: 5 WDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64 WDVR+TDTSLRDGSHHKRHQF +EV AIVAALD AGVPVIEVTHGDGLGGSSFNYGFSK Sbjct: 21 WDVRVTDTSLRDGSHHKRHQFTADEVRAIVAALDGAGVPVIEVTHGDGLGGSSFNYGFSK 80 Query: 65 TPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHF 124 TPEQELIKLAAQTA AKIAFLMLPGVGTKEDI EAQ NGGSICRIATHCTEADVSIQHF Sbjct: 81 TPEQELIKLAAQTATNAKIAFLMLPGVGTKEDIIEAQGNGGSICRIATHCTEADVSIQHF 140 Query: 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAA 184 GLARE GLETVGFLMM+HTI+PEKLA QARIMADAGCQCVYVVDSAGALVLDGVADRVAA Sbjct: 141 GLARERGLETVGFLMMSHTISPEKLAKQARIMADAGCQCVYVVDSAGALVLDGVADRVAA 200 Query: 185 LVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVF 244 +VAELG DAQVGFHGHENLGLGVANS+EAVRAGAKQIDGS RRFGAGAGNAPVEALIGVF Sbjct: 201 VVAELGSDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSTRRFGAGAGNAPVEALIGVF 260 Query: 245 DKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYG 304 DKIGVKTG E+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ ERYG Sbjct: 261 DKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQGERYG 320 Query: 305 VPAHQLLHRAGQRKLIGGQEDQLIDIALEIKRE 337 VPAHQLLHRAG+RKLIGGQEDQLIDIALEI+RE Sbjct: 321 VPAHQLLHRAGERKLIGGQEDQLIDIALEIQRE 353 >tr|C6GCU5|C6GCU5_9NOCA Tax_Id=1830 (hsaF)SubName: Full=HsaF;[Rhodococcus ruber] Length = 352 Score = 551 bits (1419), Expect = e-155 Identities = 273/336 (81%), Positives = 298/336 (88%) Query: 5 WDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64 WD+R+TDTSLRDGSHHKRHQF +EEV A+VAALD +GVPVIEVTHGDGLGGSSFNYGFSK Sbjct: 16 WDIRVTDTSLRDGSHHKRHQFDREEVRAVVAALDLSGVPVIEVTHGDGLGGSSFNYGFSK 75 Query: 65 TPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHF 124 PEQELIK+A TA+ AKIAFLMLPGVG KEDI EAQDNG SICRIATHCTEADVS+QHF Sbjct: 76 VPEQELIKIAVDTAQHAKIAFLMLPGVGIKEDIVEAQDNGASICRIATHCTEADVSVQHF 135 Query: 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAA 184 GLARE GLETVGFLMMAHT+ PEKLA QARIMADAGCQCVYVVDSAGALVL+ V +RV A Sbjct: 136 GLARERGLETVGFLMMAHTVTPEKLAEQARIMADAGCQCVYVVDSAGALVLEQVTERVEA 195 Query: 185 LVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVF 244 LVAELG DAQVGFHGHENLGLGVANS+ AVRAGA+QIDGS RRFGAGAGN PVEA +GV Sbjct: 196 LVAELGSDAQVGFHGHENLGLGVANSIAAVRAGARQIDGSARRFGAGAGNTPVEAFVGVC 255 Query: 245 DKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYG 304 DK+G+KTG EDVVRP MPAECLLDR AL+MGY+GVYSSFL+HA RQ+ERYG Sbjct: 256 DKVGIKTGIDFFAIADAAEDVVRPVMPAECLLDRQALMMGYAGVYSSFLRHAERQAERYG 315 Query: 305 VPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQES 340 V A +LL RAG+RKLIGGQEDQLIDIALE++REQ+S Sbjct: 316 VSAAELLVRAGKRKLIGGQEDQLIDIALELQREQQS 351 >sp|Q0S815|HOA3_RHOSR Tax_Id=101510 (hsaF)RecName: Full=4-hydroxy-2-oxovalerate aldolase 3; Short=HOA 3; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 3; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 3;[Rhodococcus sp.] Length = 339 Score = 545 bits (1404), Expect = e-153 Identities = 275/338 (81%), Positives = 296/338 (87%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 M WD+R+TDTSLRDGSHHKRHQF EEV AIV ALD AGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MRSSWDIRVTDTSLRDGSHHKRHQFTGEEVRAIVGALDHAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSK PEQELI +A TAK AKIAFLMLPG+G K+DI AQDNG SICRIATHCTEADVS Sbjct: 61 GFSKVPEQELISIAVDTAKNAKIAFLMLPGLGIKDDIIVAQDNGASICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLAR+ GLETVGFLMMAH+IAPEKLA QARIMADAGCQCVYVVDSAGALVL+ V+D Sbjct: 121 IQHFGLARDRGLETVGFLMMAHSIAPEKLAKQARIMADAGCQCVYVVDSAGALVLEQVSD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV ALV ELG DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVEA Sbjct: 181 RVEALVQELGSDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAF 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 +GV DKIGVKTG EDVVRPAMPAECLLDR AL+MGY+GVYSSFLKHA RQ+ Sbjct: 241 VGVCDKIGVKTGIDFFAIADAAEDVVRPAMPAECLLDRQALMMGYAGVYSSFLKHAERQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ 338 ERYGV + +LL RAG+RKL+GGQEDQLIDIALE++RE+ Sbjct: 301 ERYGVSSAELLVRAGKRKLVGGQEDQLIDIALELQRER 338 >sp|C0ZPX1|HOA1_RHOE4 Tax_Id=234621 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Rhodococcus erythropolis] Length = 347 Score = 543 bits (1399), Expect = e-152 Identities = 274/333 (82%), Positives = 293/333 (87%) Query: 5 WDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64 WD+R+TDTSLRDGSHHKRHQF EEV AIV ALD AGVPVIEVTHGDGLGGSSFNYGFSK Sbjct: 11 WDIRVTDTSLRDGSHHKRHQFTVEEVRAIVGALDGAGVPVIEVTHGDGLGGSSFNYGFSK 70 Query: 65 TPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHF 124 TPEQELIK A +TA AKIAFLMLPG+G K+DI AQDNG SICRIATHCTEADVSIQHF Sbjct: 71 TPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHCTEADVSIQHF 130 Query: 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAA 184 GLARE GLETVGFLMMAH+I PEKLA QARIMADAGCQCVYVVDSAGALVL+ V+DRV A Sbjct: 131 GLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALVLEQVSDRVEA 190 Query: 185 LVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVF 244 LV ELG DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVEA +GV Sbjct: 191 LVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAFVGVC 250 Query: 245 DKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYG 304 DKIGVKTG EDVVRPAMP ECLLDR AL+MGY+GVYSSFLKHA RQ+ERYG Sbjct: 251 DKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLKHAERQAERYG 310 Query: 305 VPAHQLLHRAGQRKLIGGQEDQLIDIALEIKRE 337 V + +LL RAG+RKL+GGQEDQLIDIALE++RE Sbjct: 311 VSSAELLVRAGKRKLVGGQEDQLIDIALELQRE 343 >sp|C1BAJ4|HOA3_RHOOB Tax_Id=632772 RecName: Full=4-hydroxy-2-oxovalerate aldolase 3; Short=HOA 3; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 3; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 3;[Rhodococcus opacus] Length = 339 Score = 542 bits (1396), Expect = e-152 Identities = 272/337 (80%), Positives = 296/337 (87%) Query: 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60 M+ WD+R+TDTSLRDGSHHKRHQF +EV AIV ALD+AGVPVIEVTHGDGLGGSSFNY Sbjct: 1 MSSSWDIRVTDTSLRDGSHHKRHQFTGDEVRAIVGALDSAGVPVIEVTHGDGLGGSSFNY 60 Query: 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120 GFSK PEQELI +A TA+ AKIAFLMLPG+G K+DI AQDNG SICRIATHCTEADVS Sbjct: 61 GFSKVPEQELISIAVDTARNAKIAFLMLPGLGIKDDIIVAQDNGASICRIATHCTEADVS 120 Query: 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180 IQHFGLAR+ GLETVGFLMMAH+I PEKLA QARIMADAGCQCVYVVDSAGALVL+ V+D Sbjct: 121 IQHFGLARDRGLETVGFLMMAHSIPPEKLARQARIMADAGCQCVYVVDSAGALVLEQVSD 180 Query: 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240 RV ALV ELG DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVEA Sbjct: 181 RVEALVQELGADAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAF 240 Query: 241 IGVFDKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300 +GV DKIGVKTG EDVVRPAMPAECLLDR AL+MGY+GVYSSFLKHA RQ+ Sbjct: 241 VGVCDKIGVKTGIDFFAIADAAEDVVRPAMPAECLLDRQALMMGYAGVYSSFLKHAERQA 300 Query: 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKRE 337 ERYGV + +LL RAG+RKL+GGQEDQLIDIALE++RE Sbjct: 301 ERYGVSSAELLVRAGKRKLVGGQEDQLIDIALELQRE 337 >tr|C3JUT2|C3JUT2_RHOER Tax_Id=596309 (dmpG)SubName: Full=4-hydroxy-2-oxovalerate aldolase; EC=4.1.3.-;[Rhodococcus erythropolis SK121] Length = 344 Score = 540 bits (1392), Expect = e-152 Identities = 273/333 (81%), Positives = 292/333 (87%) Query: 5 WDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64 WD+R+TDTSLRDGSHHKRHQF EV AIV ALD AGVPVIEVTHGDGLGGSSFNYGFSK Sbjct: 8 WDIRVTDTSLRDGSHHKRHQFTVVEVRAIVGALDGAGVPVIEVTHGDGLGGSSFNYGFSK 67 Query: 65 TPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHF 124 TPEQELIK A +TA AKIAFLMLPG+G K+DI AQDNG SICRIATHCTEADVSIQHF Sbjct: 68 TPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHCTEADVSIQHF 127 Query: 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAA 184 GLARE GLETVGFLMMAH+I PEKLA QARIMADAGCQCVYVVDSAGALVL+ V+DRV A Sbjct: 128 GLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALVLEQVSDRVEA 187 Query: 185 LVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVF 244 LV ELG DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVEA +GV Sbjct: 188 LVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAFVGVC 247 Query: 245 DKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYG 304 DKIGVKTG EDVVRPAMP ECLLDR AL+MGY+GVYSSFLKHA RQ+ERYG Sbjct: 248 DKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLKHAERQAERYG 307 Query: 305 VPAHQLLHRAGQRKLIGGQEDQLIDIALEIKRE 337 V + +LL RAG+RKL+GGQEDQLIDIALE++RE Sbjct: 308 VSSAELLVRAGKRKLVGGQEDQLIDIALELQRE 340 >sp|Q5Z2N2|HOA1_NOCFA Tax_Id=37329 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Nocardia farcinica] Length = 345 Score = 537 bits (1383), Expect = e-151 Identities = 268/338 (79%), Positives = 297/338 (87%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 D+R+TDTSLRDGSHHKRHQF EV IVAALD AGVPVIEVTHGDGLGGSSFNYGFSKT Sbjct: 8 DIRVTDTSLRDGSHHKRHQFTATEVRDIVAALDGAGVPVIEVTHGDGLGGSSFNYGFSKT 67 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 PEQEL+ +AAQTAK+AKIA LMLPGVG KEDIK +QDNG SICRIATHCTEADVSIQHFG Sbjct: 68 PEQELVTIAAQTAKQAKIAVLMLPGVGVKEDIKVSQDNGASICRIATHCTEADVSIQHFG 127 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 LARELGLETVGFLMM+HT PE LA QARIMADAGCQCVY+VDSAGALVL+ V+DRVAA+ Sbjct: 128 LARELGLETVGFLMMSHTQPPEVLAKQARIMADAGCQCVYIVDSAGALVLEQVSDRVAAV 187 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 VAELG+DAQVGFHGHENL L VANS+ A+RAGA QIDGS RRFGAGAGN PVEAL+GV D Sbjct: 188 VAELGDDAQVGFHGHENLDLAVANSIYAIRAGATQIDGSARRFGAGAGNTPVEALVGVCD 247 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 K+G++TG EDVVRPAMP ECLLDR AL+MGY+GVYSSFLKHA RQ+ERYGV Sbjct: 248 KLGIRTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLKHAERQAERYGV 307 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQV 343 A ++L RAG+RKL+GGQEDQLIDIALE++REQ++ V Sbjct: 308 SAAEMLVRAGRRKLVGGQEDQLIDIALELQREQQTATV 345 >tr|C5II23|C5II23_9NOCA Tax_Id=646677 SubName: Full=4-hydroxy-2-oxovalerate aldolase; Flags: Fragment;[Rhodococcus sp. CECT 3014] Length = 333 Score = 528 bits (1359), Expect = e-148 Identities = 266/323 (82%), Positives = 283/323 (87%) Query: 5 WDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64 WD+R+TDTSLRDGSHHKRHQF EEV AIV ALD AGVPVIEVTHGDGLGGSSFNYGFSK Sbjct: 11 WDIRVTDTSLRDGSHHKRHQFTVEEVRAIVGALDGAGVPVIEVTHGDGLGGSSFNYGFSK 70 Query: 65 TPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHF 124 TPEQELIK A +TA AKIAFLMLPG+G K+DI AQDNG SICRIATHCTEADVSIQHF Sbjct: 71 TPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHCTEADVSIQHF 130 Query: 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAA 184 GLARE GLETVGFLMMAH+I PEKLA QARIMADAGCQCVYVVDSAGALVL+ V+DRV A Sbjct: 131 GLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALVLEQVSDRVEA 190 Query: 185 LVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVF 244 LV ELG DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVEA +GV Sbjct: 191 LVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAFVGVC 250 Query: 245 DKIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYG 304 DKIGVKTG EDVVRPAMP ECLLDR AL+MGY+GVYSSFLKHA RQ+ERYG Sbjct: 251 DKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLKHAERQAERYG 310 Query: 305 VPAHQLLHRAGQRKLIGGQEDQL 327 V + +LL RAG+RKL+GGQEDQL Sbjct: 311 VSSAELLVRAGKRKLVGGQEDQL 333 >tr|D0L3M4|D0L3M4_GORB4 Tax_Id=526226 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Gordonia bronchialis] Length = 358 Score = 517 bits (1332), Expect = e-145 Identities = 253/335 (75%), Positives = 293/335 (87%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 D+RITD+SLRDGSHHKRHQF ++EV +IV ALD AGVPVIEVTHGDGLGGSSFNYGFSKT Sbjct: 20 DIRITDSSLRDGSHHKRHQFTEDEVRSIVGALDEAGVPVIEVTHGDGLGGSSFNYGFSKT 79 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 PEQ+LIK AA+TAK+AKIAFLMLPG+GTK+DI+ AQDNGG ICRIATHCTEADVSIQHFG Sbjct: 80 PEQQLIKAAAETAKQAKIAFLMLPGLGTKDDIRAAQDNGGQICRIATHCTEADVSIQHFG 139 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 LAR+LGLETVGFLMM+H+ PE LAAQARIMADAGCQCVYVVDSAGALVL+ V RV AL Sbjct: 140 LARDLGLETVGFLMMSHSQPPEVLAAQARIMADAGCQCVYVVDSAGALVLEDVTVRVQAL 199 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 VAELG+DAQVGFHGHENL + VANS+ A+RAGA+QIDGS+RRFGAGAGN P EA +GV D Sbjct: 200 VAELGDDAQVGFHGHENLDIAVANSINAIRAGAQQIDGSIRRFGAGAGNTPTEAFVGVCD 259 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 K+G+ TG +DVVRPAMP+ECL+DR+A++MGY+G YSSFLKHA +ERYGV Sbjct: 260 KLGITTGVDFMKIADAAQDVVRPAMPSECLVDRSAMMMGYAGCYSSFLKHAEGHAERYGV 319 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQES 340 A ++L AG RKL+GGQEDQLIDIALE+K++ ++ Sbjct: 320 SAAEILIEAGNRKLVGGQEDQLIDIALELKKKADA 354 >tr|D1AB65|D1AB65_THECU Tax_Id=471852 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Thermomonospora curvata DSM 43183] Length = 344 Score = 504 bits (1298), Expect = e-141 Identities = 250/333 (75%), Positives = 283/333 (84%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 D+R+TD+SLRDGSH KRHQF + V ++VAALD AGVPVIEV HGDGLGGSSF YGFSKT Sbjct: 9 DIRVTDSSLRDGSHAKRHQFTVDHVTSVVAALDEAGVPVIEVAHGDGLGGSSFTYGFSKT 68 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 PEQELIK A +TA AKIAFLMLPGVG K+DI+EA DNG ICRIATHCTEADVS+QHFG Sbjct: 69 PEQELIKAAVKTATRAKIAFLMLPGVGVKDDIREAADNGAQICRIATHCTEADVSVQHFG 128 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 LAR+LGLETVGFLMMAH+ PE LA QARIMADAGCQCVYVVDSAGAL+L+ +DR+AAL Sbjct: 129 LARDLGLETVGFLMMAHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILEETSDRIAAL 188 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 VAELG+DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGSVRR GAGAGN P+EA I V D Sbjct: 189 VAELGDDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSVRRLGAGAGNTPLEAFIAVCD 248 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 K+G++TG EDVVRP M +ECLL R ++MGY+GVYSSFLKHA R +ERYGV Sbjct: 249 KLGIRTGVDVFKIVDAAEDVVRPVMDSECLLGRMEIMMGYAGVYSSFLKHADRLAERYGV 308 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ 338 Q+L RAG+RKL+GGQEDQLIDIA+E+ +EQ Sbjct: 309 SGAQILVRAGERKLVGGQEDQLIDIAIELAKEQ 341 >sp|C1AYB4|HOA5_RHOOB Tax_Id=632772 RecName: Full=4-hydroxy-2-oxovalerate aldolase 5; Short=HOA 5; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 5; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 5;[Rhodococcus opacus] Length = 352 Score = 488 bits (1257), Expect = e-136 Identities = 245/339 (72%), Positives = 283/339 (83%), Gaps = 1/339 (0%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 D+R+TD+SLRDGSH KRHQF E V +IV ALDAAGVPVIEVTHGDGLGGSSFNYGFS T Sbjct: 8 DIRVTDSSLRDGSHAKRHQFTVEHVRSIVGALDAAGVPVIEVTHGDGLGGSSFNYGFSHT 67 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 PEQELIK A +TA++AKIAFLMLPG+G + DI+EA DNG SICRIATHCTEAD+S+QHFG Sbjct: 68 PEQELIKAAVETAEQAKIAFLMLPGLGVRSDIREAADNGASICRIATHCTEADISVQHFG 127 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 LAR+LGLETVGFLMM+H+ PE LA QARIMADAGCQCVYVVDSAGAL+L+ V+DRV+AL Sbjct: 128 LARDLGLETVGFLMMSHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILNAVSDRVSAL 187 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 VAELG+DAQVGFHGHENLGLGVANSV AV AGA QIDGS RRFGAGAGN PVEA V + Sbjct: 188 VAELGDDAQVGFHGHENLGLGVANSVLAVEAGALQIDGSTRRFGAGAGNTPVEAFAAVTE 247 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 K+G++TG EDVVRP M +CLLDR +L MGY+GVYSSFLKHA + RYGV Sbjct: 248 KLGIRTGIDTLKIIDAAEDVVRPIMDGDCLLDRLSLTMGYAGVYSSFLKHADSHASRYGV 307 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVA 344 ++L AG+RKL+GGQEDQLI+IAL + +++S + A Sbjct: 308 SGAEILIEAGRRKLVGGQEDQLIEIALGL-ADRKSAETA 345 >sp|Q0S4F8|HOA4_RHOSR Tax_Id=101510 RecName: Full=4-hydroxy-2-oxovalerate aldolase 4; Short=HOA 4; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 4; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 4;[Rhodococcus sp.] Length = 352 Score = 487 bits (1253), Expect = e-135 Identities = 243/342 (71%), Positives = 280/342 (81%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 D+R+TD+SLRDGSH KRHQF E V +IV ALDAAGVPVIEVTHGDGLGGSSFNYGFS T Sbjct: 8 DIRVTDSSLRDGSHAKRHQFTVEHVRSIVGALDAAGVPVIEVTHGDGLGGSSFNYGFSHT 67 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 PEQELIK A +TA+ A+IAFLMLPG+G + DI+EA DNG SICRIATHCTEAD+S+QHFG Sbjct: 68 PEQELIKAAVETAERARIAFLMLPGLGVQSDIREAADNGASICRIATHCTEADISVQHFG 127 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 LARELGLETVGFLMM+H+ PE LA QARIMADAGCQCVYVVDSAGAL+L+ V+DRV+AL Sbjct: 128 LARELGLETVGFLMMSHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILNAVSDRVSAL 187 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 VAELG+DAQVGFHGHENLGLGVANSV AV AGA QIDGS RRFGAGAGN PVEA V + Sbjct: 188 VAELGDDAQVGFHGHENLGLGVANSVLAVEAGALQIDGSTRRFGAGAGNTPVEAFAAVTE 247 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 K+G++TG EDVVRP M +C LDR +L+MGY+GVYSSFLKHA + RYGV Sbjct: 248 KLGIRTGIDTLKIIDAAEDVVRPIMDGDCQLDRLSLMMGYAGVYSSFLKHADSHARRYGV 307 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVASRR 347 ++L AG+RKL+GGQEDQLI+IAL + +G + + Sbjct: 308 SGAEILIEAGRRKLVGGQEDQLIEIALGLADRGPAGSAVAEK 349 >tr|C2AK53|C2AK53_TSUPA Tax_Id=521096 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Tsukamurella paurometabola DSM 20162] Length = 349 Score = 422 bits (1086), Expect = e-116 Identities = 214/333 (64%), Positives = 254/333 (76%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 DVRI DTSLRDGSH HQF ++ V V ALD AGV +IEVTHGDGLGGS+FNYGFS Sbjct: 15 DVRIVDTSLRDGSHAMAHQFTEQNVRDTVRALDDAGVSLIEVTHGDGLGGSTFNYGFSLV 74 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 E++LI A A++AKIA LMLPG+GT EDI+ A D G RIATHCTEADVSIQHFG Sbjct: 75 DERKLIAAAVDEAQQAKIAVLMLPGLGTVEDIRVAADLGAGALRIATHCTEADVSIQHFG 134 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 ARELGLETVGFLM++H APE LA QARIMADAGCQCVYVVDSAGAL+L+ ADRVAAL Sbjct: 135 AARELGLETVGFLMLSHMSAPEALAKQARIMADAGCQCVYVVDSAGALILEDAADRVAAL 194 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 VAELG DA VG+HGH+NL GVANSV A RAGAKQIDGS+ GAGAGN+P E L F+ Sbjct: 195 VAELGADAHVGYHGHQNLSFGVANSVLAYRAGAKQIDGSLLALGAGAGNSPTEVLAATFE 254 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 ++GV+TG EDVV+P + ++DR++++ GY+GVYSSFL HA R + RYGV Sbjct: 255 RLGVRTGTDKDALMAAAEDVVKPYITRLPVMDRSSIVQGYAGVYSSFLLHAERAAARYGV 314 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ 338 PAH++L+ G+R +GGQED +I IA+E+ Q Sbjct: 315 PAHEILYECGRRGYVGGQEDMIIAIAVEMSAAQ 347 >tr|D1A3K8|D1A3K8_THECU Tax_Id=471852 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Thermomonospora curvata DSM 43183] Length = 355 Score = 410 bits (1053), Expect = e-112 Identities = 207/332 (62%), Positives = 248/332 (74%) Query: 7 VRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTP 66 VRITD++LRDGSH HQF +E+V A V ALDAAGV VIEV+HGDGLGGSSFNYGFS Sbjct: 13 VRITDSTLRDGSHAMAHQFTEEQVRATVHALDAAGVEVIEVSHGDGLGGSSFNYGFSAVD 72 Query: 67 EQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGL 126 E +L+ A A AKIA L+LPGVGT D+K A D G S+ RIATHCTEADVS QHF Sbjct: 73 EIDLVAAAVDEAVNAKIAVLLLPGVGTVRDLKRAHDAGASVARIATHCTEADVSCQHFAA 132 Query: 127 ARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALV 186 ARELG+ETVGFLM+AH I PE+LA QARIM DAG QCVYVVDSAGALVL V RV ALV Sbjct: 133 ARELGMETVGFLMLAHRIGPEELARQARIMVDAGAQCVYVVDSAGALVLSDVQARVQALV 192 Query: 187 AELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDK 246 E+G +AQVGFHGH+NL LGVANSV A + GA+QIDG++ GAGAGN+P E L F++ Sbjct: 193 REIGHEAQVGFHGHQNLSLGVANSVLAYQNGARQIDGALCALGAGAGNSPTEILAATFER 252 Query: 247 IGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVP 306 + ++TG E+VVRP +P DR A++ GY+GVYSSFL HA R +ERYGVP Sbjct: 253 LNIETGVNVQAALAAAEEVVRPYLPRLPWADRAAIVQGYAGVYSSFLLHAERAAERYGVP 312 Query: 307 AHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ 338 AH++L R G+ +GGQED +IDIA+++ E+ Sbjct: 313 AHEILQRVGEAGYVGGQEDMIIDIAVQLAEER 344 >tr|C8XHR8|C8XHR8_NAKMY Tax_Id=479431 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Nakamurella multipartita] Length = 352 Score = 396 bits (1018), Expect = e-108 Identities = 196/332 (59%), Positives = 246/332 (74%) Query: 7 VRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTP 66 VR+TD++LRDGSH RHQF + V +V ALDAAGV VIEVTHGDGL GSSFNYGF K Sbjct: 19 VRLTDSTLRDGSHAVRHQFTTDNVTDVVTALDAAGVSVIEVTHGDGLAGSSFNYGFGKHT 78 Query: 67 EQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGL 126 + EL+ A + A AKIA L+LPG+GT D+K+ G I R+ATHCTEADVS++HF Sbjct: 79 DAELVAAAVRAATRAKIAVLVLPGLGTVHDLKQVHSAGAQIARVATHCTEADVSVEHFTA 138 Query: 127 ARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALV 186 ARELG+ETVGFLM++H I PE+LA QARIMADAGCQCVYVVDSAGAL+ D V DRV ALV Sbjct: 139 ARELGMETVGFLMLSHRIGPEQLAKQARIMADAGCQCVYVVDSAGALLPDMVRDRVQALV 198 Query: 187 AELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDK 246 AELG+DAQVGFHGH+NL LGVANS+ A GA+QIDG++ GAGAGN+P E L VFD Sbjct: 199 AELGDDAQVGFHGHQNLSLGVANSIVAYENGARQIDGTLCALGAGAGNSPTEILATVFDV 258 Query: 247 IGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVP 306 +GV TG ED+V+P + + DR +++ G GVY+SFL HA R ++RYGV Sbjct: 259 MGVPTGVDAAKVLDAAEDIVKPMITRMPVADRASIVQGRYGVYNSFLLHAERAADRYGVS 318 Query: 307 AHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ 338 +H++L + G+ +GGQED +ID+A+ + ++ Sbjct: 319 SHEILRKVGEAGYVGGQEDMIIDVAIGLAAQR 350 >sp|Q0RXC3|HOA6_RHOSR Tax_Id=101510 RecName: Full=4-hydroxy-2-oxovalerate aldolase 6; Short=HOA 6; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 6; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 6;[Rhodococcus sp.] Length = 354 Score = 387 bits (995), Expect = e-106 Identities = 186/331 (56%), Positives = 243/331 (73%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 DVRI DT+LRDGSH + HQF + +V V ALD AGV VIEVTHGDGLGGS+FNYGFS+ Sbjct: 9 DVRIVDTTLRDGSHAQSHQFTESQVRDTVRALDGAGVEVIEVTHGDGLGGSTFNYGFSRI 68 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 + EL+++AA TA++AKIA L++PG+GT +D+++A D G + RIATHCTEADVS+QHF Sbjct: 69 SDLELVQVAADTAEQAKIAVLLVPGIGTADDLRKAADRGAEVVRIATHCTEADVSLQHFE 128 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 +AR+LG++T GFLMMAH PE+LA QAR+M DAGCQ YV DSAGAL++ DR AL Sbjct: 129 IARDLGMQTCGFLMMAHRTTPEELARQARLMVDAGCQVPYVTDSAGALLMHEAKDRFDAL 188 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 + E+G+DA VG+HGH+N+ LGVANSV A AG + IDGS+ GAGAGN+P E L +FD Sbjct: 189 ITEVGDDAWVGYHGHQNMSLGVANSVIAYEAGVRYIDGSLCALGAGAGNSPTELLAAIFD 248 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 ++ + TG E VVRP + +DRNA++ G+ GVYSSFL HA RYGV Sbjct: 249 RMNIATGLDVMATLDAAETVVRPYLNRWPKIDRNAIVQGWVGVYSSFLLHAETAGARYGV 308 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKR 336 P H++L R G+ +GGQED +ID+A+++ + Sbjct: 309 PVHEILRRCGELGYVGGQEDMIIDVAIQLAK 339 >sp|B9LCM1|HOA_CHLSY Tax_Id=480224 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Chloroflexus aurantiacus] Length = 343 Score = 361 bits (927), Expect = 6e-98 Identities = 186/333 (55%), Positives = 233/333 (69%), Gaps = 2/333 (0%) Query: 8 RITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPE 67 R+TDT+LRDGSH RHQF +++V IV ALD AGVPVIEV+HGDGL GSS YGFS T E Sbjct: 5 RLTDTTLRDGSHPMRHQFTRQQVATIVQALDRAGVPVIEVSHGDGLAGSSLQYGFSHTSE 64 Query: 68 QELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGLA 127 +LI+ A Q A+ AKIA LMLPG+GT++++KEA G + RIAT CTEAD+S QHFGLA Sbjct: 65 FDLIETARQHAERAKIAALMLPGIGTRQELKEAVARGVQVVRIATQCTEADISEQHFGLA 124 Query: 128 RELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALVA 187 +ELGLETVGFLMMAH PE+LA QA++M G CVY+VDSAGA++ A RV AL Sbjct: 125 KELGLETVGFLMMAHMRPPEELARQAKLMESYGADCVYIVDSAGAMLPQDAAARVQALKD 184 Query: 188 ELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDKI 247 L QVGFH H NLGLG+AN++ A+ AGA QIDG +R GAGAGNA E L V D++ Sbjct: 185 TL--SVQVGFHAHNNLGLGIANTLAALEAGADQIDGCLRGLGAGAGNAATELLAAVLDRL 242 Query: 248 GVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVPA 307 G+ G E VV P MP + DR+A+ +GY+GVYS+FL HA R +Y V Sbjct: 243 GLNPGLDVFSLMDAAEYVVAPIMPFQPFPDRDAITIGYAGVYSTFLLHAKRAGAQYNVDP 302 Query: 308 HQLLHRAGQRKLIGGQEDQLIDIALEIKREQES 340 ++L G+R+ + GQED +ID+ALE+ R +S Sbjct: 303 REILVELGRRQAVAGQEDWIIDVALELSRRHQS 335 >sp|A9W9U3|HOA_CHLAA Tax_Id=324602 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Chloroflexus aurantiacus] Length = 343 Score = 361 bits (927), Expect = 6e-98 Identities = 186/333 (55%), Positives = 233/333 (69%), Gaps = 2/333 (0%) Query: 8 RITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPE 67 R+TDT+LRDGSH RHQF +++V IV ALD AGVPVIEV+HGDGL GSS YGFS T E Sbjct: 5 RLTDTTLRDGSHPMRHQFTRQQVATIVQALDRAGVPVIEVSHGDGLAGSSLQYGFSHTSE 64 Query: 68 QELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGLA 127 +LI+ A Q A+ AKIA LMLPG+GT++++KEA G + RIAT CTEAD+S QHFGLA Sbjct: 65 FDLIETARQHAERAKIAALMLPGIGTRQELKEAVARGVQVVRIATQCTEADISEQHFGLA 124 Query: 128 RELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALVA 187 +ELGLETVGFLMMAH PE+LA QA++M G CVY+VDSAGA++ A RV AL Sbjct: 125 KELGLETVGFLMMAHMRPPEELARQAKLMESYGADCVYIVDSAGAMLPQDAAARVQALKD 184 Query: 188 ELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDKI 247 L QVGFH H NLGLG+AN++ A+ AGA QIDG +R GAGAGNA E L V D++ Sbjct: 185 TL--SVQVGFHAHNNLGLGIANTLAALEAGADQIDGCLRGLGAGAGNAATELLAAVLDRL 242 Query: 248 GVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVPA 307 G+ G E VV P MP + DR+A+ +GY+GVYS+FL HA R +Y V Sbjct: 243 GLNPGLDVFSLMDAAEYVVAPIMPFQPFPDRDAITIGYAGVYSTFLLHAKRAGAQYNVDP 302 Query: 308 HQLLHRAGQRKLIGGQEDQLIDIALEIKREQES 340 ++L G+R+ + GQED +ID+ALE+ R +S Sbjct: 303 REILVELGRRQAVAGQEDWIIDVALELSRRHQS 335 >sp|B9L2J0|HOA_THERP Tax_Id=309801 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Thermomicrobium roseum] Length = 356 Score = 360 bits (925), Expect = 1e-97 Identities = 183/337 (54%), Positives = 236/337 (70%), Gaps = 2/337 (0%) Query: 8 RITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPE 67 R+TDT+LRDGSH RHQF +E+V AIVAALD AGVPVIEVTHGDGL GSS YGFS T E Sbjct: 8 RVTDTTLRDGSHAMRHQFTREQVRAIVAALDEAGVPVIEVTHGDGLAGSSIQYGFSATSE 67 Query: 68 QELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGLA 127 ELI+ AA+TAK AKIA L+LPG+GT+ ++ A + G + RIAT CTEAD+S QHFG+A Sbjct: 68 LELIEEAAKTAKRAKIAALLLPGIGTRRELSAAIERGIKVVRIATQCTEADISEQHFGMA 127 Query: 128 RELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALVA 187 +E+GLETVGFLMMAH PE LA QA +M G CVY+VDSAGA++ D V RVAAL Sbjct: 128 KEMGLETVGFLMMAHMRPPEFLAEQAALMESYGADCVYIVDSAGAMLPDDVRRRVAALKE 187 Query: 188 ELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDKI 247 L QVGFH H NLGL + N++ A+ GA Q+DG +R GAGAGNAP E + V DK+ Sbjct: 188 RL--SIQVGFHAHNNLGLAIGNTLAAIEEGADQVDGCLRGLGAGAGNAPTELIAAVLDKL 245 Query: 248 GVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVPA 307 G+ G E +V P MP + + DR+A+ +GY+GVYS+FL HA + +G+ Sbjct: 246 GINPGLDVFKLMDAAEYIVAPIMPYQPIPDRDAITIGYAGVYSTFLLHARHIAAEFGLDP 305 Query: 308 HQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVA 344 ++L G+R+ + GQED ++D+AL+I R + + + A Sbjct: 306 REILVELGRRQAVAGQEDWILDVALDILRRKRAAEGA 342 >sp|B8GBV5|HOA_CHLAD Tax_Id=326427 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Chloroflexus aggregans] Length = 343 Score = 358 bits (920), Expect = 4e-97 Identities = 183/334 (54%), Positives = 232/334 (69%), Gaps = 2/334 (0%) Query: 8 RITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPE 67 R+TDT+LRDGSH RHQF +E+V IV ALD AGVPVIEV+HGDGL GSS YGFS T E Sbjct: 5 RLTDTTLRDGSHPMRHQFTREQVAKIVQALDRAGVPVIEVSHGDGLAGSSLQYGFSHTSE 64 Query: 68 QELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGLA 127 +LI+ A A+ AKIA LMLPG+GT++++KEA G + RIAT CTEAD+S QHFGLA Sbjct: 65 FDLIETARSYAERAKIAALMLPGIGTRQELKEAVARGIQVVRIATQCTEADISEQHFGLA 124 Query: 128 RELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALVA 187 +ELGLETVGFLMMAH PE L QA++M G CVY+VDSAGA++ A RV AL Sbjct: 125 KELGLETVGFLMMAHMRPPEALVEQAKLMESYGADCVYIVDSAGAMLPHDAAARVRALKE 184 Query: 188 ELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDKI 247 L QVGFH H NLGLG+ N++ A+ AGA QIDG +R GAGAGNA E L V D++ Sbjct: 185 AL--SVQVGFHAHNNLGLGIGNTLAALEAGADQIDGCLRGLGAGAGNAATELLAAVLDRL 242 Query: 248 GVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVPA 307 G+ G E +V P MP + DR+A+ +GY+GVYS+FL HA R E+YG+ Sbjct: 243 GLNPGLDVFGLMDAAEYIVAPIMPFQPFPDRDAITIGYAGVYSTFLLHAKRAGEQYGIDP 302 Query: 308 HQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341 ++L G+R+ + GQED +ID+AL++ R + +G Sbjct: 303 REILVELGRRQAVAGQEDWIIDVALDLSRRRGAG 336 >tr|C6KWI8|C6KWI8_9BACT Tax_Id=77133 SubName: Full=4-hydroxy 2-oxovalerate aldolase;[uncultured bacterium] Length = 344 Score = 349 bits (895), Expect = 3e-94 Identities = 173/326 (53%), Positives = 227/326 (69%) Query: 9 ITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPEQ 68 I D SLRDG H RHQ ++V A+ ALDAAGV IEVTHGDGL GSSFNYGF + Sbjct: 11 IQDVSLRDGMHALRHQATPDQVAAVAGALDAAGVDAIEVTHGDGLSGSSFNYGFGSHSDL 70 Query: 69 ELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGLAR 128 E I+ AA A+I L++PG+G +D++ A+ G S RIATHCTEADVS+QH +AR Sbjct: 71 EWIEAAASVVNRARITVLLVPGIGLADDLRAARQAGASSVRIATHCTEADVSLQHIKVAR 130 Query: 129 ELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALVAE 188 +LG +T FLMMAH PE L QA++M +AG +CVYVVDS+GA++ + + RV AL Sbjct: 131 DLGYDTACFLMMAHMTTPEALLDQAKLMENAGAECVYVVDSSGAMLPEDITARVTALRGG 190 Query: 189 LGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDKIG 248 L + +VG H HENL GVANSV VRAGA ++DGS+ GAGAGNAP+EALI VFD++G Sbjct: 191 LRPETEVGIHTHENLHHGVANSVAGVRAGAVRVDGSLAGLGAGAGNAPIEALIAVFDRLG 250 Query: 249 VKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVPAH 308 TG +++VRP M +DR +L++GY+GVYSSFL+HA + ++ YGVPA Sbjct: 251 FATGCDFTRLSAAADELVRPMMDRPVRVDRESLMLGYAGVYSSFLRHAEKAAKDYGVPAS 310 Query: 309 QLLHRAGQRKLIGGQEDQLIDIALEI 334 +L G+RK+IGGQED ++D+AL++ Sbjct: 311 DILVELGKRKMIGGQEDMIVDVALDL 336 >sp|A5UWE6|HOA_ROSS1 Tax_Id=357808 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Roseiflexus sp.] Length = 338 Score = 345 bits (886), Expect = 4e-93 Identities = 177/336 (52%), Positives = 232/336 (69%), Gaps = 2/336 (0%) Query: 8 RITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPE 67 R+TDT+LRDGSH H F +++V IV ALD AGVPVIEVTHGDGL GSS YGFS+ P+ Sbjct: 5 RLTDTTLRDGSHALAHTFTRQQVRDIVRALDRAGVPVIEVTHGDGLAGSSLQYGFSRVPD 64 Query: 68 QELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGLA 127 +LI A +TA+ A+IA L+LPG+GT+ +++ A + G + RIAT CTEAD+S +HF +A Sbjct: 65 LDLIAEARETAERARIAALLLPGIGTRRELRAAVERGVQVLRIATQCTEADISEEHFKMA 124 Query: 128 RELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALVA 187 +++GLETVGFLMM+H PE LA QAR+M G CVYVVDSAGA++ A RV AL A Sbjct: 125 KDMGLETVGFLMMSHMRPPEFLAEQARLMESYGADCVYVVDSAGAMLPHDAAARVQALKA 184 Query: 188 ELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDKI 247 L QVGFH H NLGLG+ N++ A+ AGA QIDG +R GAGAGNA E L V D++ Sbjct: 185 AL--TVQVGFHAHNNLGLGIGNTLAALEAGADQIDGCLRGLGAGAGNAATEVLAAVLDRL 242 Query: 248 GVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVPA 307 G+ G E VV P MP + DR+A+ +GY+GVYS+FL HA R E+ GV Sbjct: 243 GINPGLDVLALMDAAEYVVAPIMPFQPFPDRDAITIGYAGVYSTFLLHARRIGEQLGVDP 302 Query: 308 HQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQV 343 +L G+R+ + GQED ++D+ALE+ R+Q++ V Sbjct: 303 RAILIELGRRQTVAGQEDWILDVALELVRQQQTTPV 338 >tr|C6L0Y8|C6L0Y8_9BACT Tax_Id=77133 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[uncultured bacterium] Length = 352 Score = 345 bits (885), Expect = 5e-93 Identities = 167/333 (50%), Positives = 227/333 (68%) Query: 7 VRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTP 66 V++ D SLRDG H KRHQF ++ + LD AGVP+IEVTHGDGL G+S NYGF Sbjct: 8 VKLHDMSLRDGMHAKRHQFTTADMVRVAKGLDEAGVPLIEVTHGDGLAGASVNYGFPAHT 67 Query: 67 EQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGL 126 ++E ++ K K++ L+LPG+GT ED+K QD G + R+ATHCTEADVS QH Sbjct: 68 DEEYLRAVVPEMKNTKVSALLLPGIGTVEDLKMVQDCGVATIRVATHCTEADVSEQHISY 127 Query: 127 ARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALV 186 A ++G++TVGFLMM+H + PEK+ QAR+M G CVY+ DSAG ++ D V R+ L Sbjct: 128 AAKMGMDTVGFLMMSHMVGPEKILEQARLMVGYGANCVYMTDSAGYMLPDDVTARIGLLR 187 Query: 187 AELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDK 246 AE+ + ++GFHGH NL +GVANS+ AV AGA +IDGSV GAGAGN P+E V D+ Sbjct: 188 AEIPPEVEIGFHGHHNLAMGVANSLAAVDAGATRIDGSVAGMGAGAGNTPLEVFAAVLDR 247 Query: 247 IGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVP 306 +GV+TG ED++ P M + +DR++LI+GY+GVYSSFL HA R +RYG+ Sbjct: 248 MGVETGINTFKIMDVAEDLMVPLMDHQVRVDRDSLILGYAGVYSSFLLHAKRAEQRYGIN 307 Query: 307 AHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE 339 A +L + G+R +IGGQED + D+ALE+ R ++ Sbjct: 308 ARDVLVKLGERGMIGGQEDMIEDVALELARARD 340 >sp|B0VXM7|HOA_BACST Tax_Id=1422 (pheE)RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Bacillus stearothermophilus] Length = 342 Score = 343 bits (881), Expect = 1e-92 Identities = 175/338 (51%), Positives = 230/338 (68%), Gaps = 2/338 (0%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 DV IT+ +LRDGSH HQ+ E+V I ALD A VP IEV HGDGL GSS YG S+T Sbjct: 6 DVWITEVALRDGSHAVAHQYTVEQVVKIAKALDEANVPYIEVAHGDGLAGSSLQYGLSRT 65 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 E ELI+ A K++KIA L+LPG+GT +D+++ G + RIATH TEADVS QH G Sbjct: 66 NELELIEAAVSVCKQSKIAVLLLPGIGTMKDLQQVAGLGAKMARIATHVTEADVSAQHIG 125 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 LA+ELG+ETVGFLMMAH EKL QA++M G VYVVDSAGAL+ V DR+ AL Sbjct: 126 LAKELGMETVGFLMMAHMAPVEKLVEQAKLMESYGADAVYVVDSAGALLPHEVRDRIRAL 185 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 +G ++GFHGH NL L +ANS+ A+ GA +IDGSVR GAGAGN E L+ V D Sbjct: 186 KQHVG--VEIGFHGHNNLSLAMANSLVAIEEGATRIDGSVRCLGAGAGNTQTEVLVAVLD 243 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 ++GVKTG E++V P +PA + R++L++GY+GVYSSFL HA R +E+ G+ Sbjct: 244 RLGVKTGIDLYKMMDLAEEIVAPMLPAPQEITRDSLVLGYAGVYSSFLLHARRIAEKLGM 303 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQV 343 A +L G+RK++GGQED ++D+A+E+ +++ V Sbjct: 304 DARDILVELGKRKVVGGQEDMIVDVAVEMAKKRAESLV 341 >sp|Q9ZI56|HOA_PSEST Tax_Id=316 (nahM)RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Pseudomonas stutzeri] Length = 346 Score = 343 bits (880), Expect = 2e-92 Identities = 166/340 (48%), Positives = 233/340 (68%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 +V + D SLRDG H KRHQ E++ A+ LDAAG+P+IE+THGDGLGG S NYGF Sbjct: 7 NVTLHDMSLRDGMHAKRHQISLEQMIAVATGLDAAGMPLIEITHGDGLGGRSINYGFPAH 66 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 ++E ++ K+AK++ L+LPG+GT + +K A D G S R+ATHCTEADVS QH G Sbjct: 67 SDEEYLRAVIPRLKQAKVSALLLPGIGTVDHLKMALDCGVSTIRVATHCTEADVSEQHIG 126 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 ++R+LG +TVGFLMMAH I+ EK+ QAR+M G C+Y DSAG ++ D V++++ L Sbjct: 127 MSRKLGADTVGFLMMAHMISAEKVLEQARLMESYGANCIYCTDSAGYMLPDEVSEKIGLL 186 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 AEL ++GFHGH N+G+ +ANS+ A+ AGA +IDGSV GAGAGN P+E + V Sbjct: 187 RAELNPATEIGFHGHHNMGMAIANSLAAIEAGASRIDGSVAGLGAGAGNTPLEVFVAVCK 246 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 ++GV+TG ED+V P M +DR+AL +GY+GVYSSFL A R ++YGV Sbjct: 247 RMGVETGIDLYKIMDVAEDIVVPMMDQPIRVDRDALTLGYAGVYSSFLLFAQRAEKKYGV 306 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVAS 345 PA +L G+R +GGQED + D+AL++ R +++ +V++ Sbjct: 307 PARDILVELGRRGTVGGQEDMIEDLALDMSRARQNQKVSA 346 >tr|Q49KG7|Q49KG7_PSEPU Tax_Id=303 (nahM)SubName: Full=NahM;[Pseudomonas putida] Length = 346 Score = 343 bits (880), Expect = 2e-92 Identities = 166/340 (48%), Positives = 233/340 (68%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 +V + D SLRDG H KRHQ E++ A+ LDAAG+P+IE+THGDGLGG S NYGF Sbjct: 7 NVTLHDMSLRDGMHAKRHQISLEQMIAVATGLDAAGMPLIEITHGDGLGGRSINYGFPAH 66 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 ++E ++ K+AK++ L+LPG+GT + +K A D G S R+ATHCTEADVS QH G Sbjct: 67 SDEEYLRAVIPRLKQAKVSALLLPGIGTVDHLKMALDCGVSTIRVATHCTEADVSEQHIG 126 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 ++R+LG +TVGFLMMAH I+ EK+ QAR+M G C+Y DSAG ++ D V++++ L Sbjct: 127 MSRKLGADTVGFLMMAHMISAEKVLEQARLMESYGANCIYCTDSAGYMLPDEVSEKIGLL 186 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 AEL ++GFHGH N+G+ +ANS+ A+ AGA +IDGSV GAGAGN P+E + V Sbjct: 187 RAELNPATEIGFHGHHNMGMAIANSLAAIEAGASRIDGSVAGLGAGAGNTPLEVFVAVCK 246 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 ++GV+TG ED+V P M +DR+AL +GY+GVYSSFL A R ++YGV Sbjct: 247 RMGVETGIDLYKIMDVAEDIVVPMMDQPIRVDRDALTLGYAGVYSSFLLFAQRAEKKYGV 306 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVAS 345 PA +L G+R +GGQED + D+AL++ R +++ +V++ Sbjct: 307 PARDILVELGRRGTVGGQEDMIEDLALDMSRARQNQKVSA 346 >sp|Q764S0|HOA_BACPJ Tax_Id=209076 (nahM)RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Bacillus sp.] Length = 337 Score = 343 bits (879), Expect = 2e-92 Identities = 172/328 (52%), Positives = 233/328 (71%), Gaps = 2/328 (0%) Query: 7 VRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTP 66 +RI DT+LRDGSH RH+F KE V IV ALD AGVPVIEV+HGDGLGGSS YG S Sbjct: 6 IRIMDTTLRDGSHAIRHRFTKENVRQIVQALDEAGVPVIEVSHGDGLGGSSLQYGMSLVE 65 Query: 67 EQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFGL 126 E ELI+ AA+T++ AKIA L+LPG+GTK+++++A+D G + RIAT C+EADVS QHFGL Sbjct: 66 EMELIEEAAKTSRRAKIAALLLPGIGTKKELQQAKDCGIQMVRIATQCSEADVSEQHFGL 125 Query: 127 ARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAALV 186 A+ELGLETVGFLMMAH ++PE+LA QA++M G VY+VDSAG ++ V DRV AL Sbjct: 126 AKELGLETVGFLMMAHMLSPEELAQQAKLMESYGADIVYIVDSAGTMLPQDVIDRVIALK 185 Query: 187 AELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFDK 246 L + +GFH H NLGL + NS+ A++AGA ID S R GAG+GN E L+ V + Sbjct: 186 KVL--NVPIGFHAHNNLGLAIGNSLAAIQAGATNIDASTRGLGAGSGNTQTEVLVAVLSR 243 Query: 247 IGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGVP 306 +G++TG E +V P M + +++R+AL +G++GVYS+FL HA + E++GV Sbjct: 244 MGIETGIDLFQIMDAAEYIVDPLMDSPMIVNRDALTIGFTGVYSTFLWHAKQAGEKFGVD 303 Query: 307 AHQLLHRAGQRKLIGGQEDQLIDIALEI 334 ++L G+RK + GQED ++D+A ++ Sbjct: 304 PREILIELGRRKAVAGQEDWILDVASDL 331 >tr|Q6WE18|Q6WE18_PSEPU Tax_Id=303 (nahM)SubName: Full=2-oxo-4-hydroxypentanoate aldolase;[Pseudomonas putida] Length = 346 Score = 342 bits (878), Expect = 3e-92 Identities = 166/340 (48%), Positives = 233/340 (68%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 +V + D SLRDG H KRHQ E++ A+ LDAAG+P+IE+THGDGLGG S NYGF Sbjct: 7 NVTLHDMSLRDGMHAKRHQISLEQMIAVATGLDAAGMPLIEITHGDGLGGRSINYGFPAH 66 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 ++E ++ K+AK++ L+LPG+GT + +K A D G S R+ATHCTEADVS QH G Sbjct: 67 SDEEYLRAVIPRLKQAKVSALLLPGIGTVDHLKMALDCGVSTIRVATHCTEADVSEQHIG 126 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 ++R+LG +TVGFLMMAH I+ EK+ QAR+M G C+Y DSAG ++ D V++++ L Sbjct: 127 MSRKLGADTVGFLMMAHMISAEKVLEQARLMESYGANCIYCTDSAGYMLPDEVSEKIGLL 186 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 AEL ++GFHGH N+G+ +ANS+ A+ AGA +IDGSV GAGAGN P+E + V Sbjct: 187 RAELNPATEIGFHGHHNMGMAIANSLAAIEAGASRIDGSVAGLGAGAGNTPLEVFVAVCK 246 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 ++GV+TG ED+V P M +DR+AL +GY+GVYSSFL A R ++YGV Sbjct: 247 RMGVETGIDLYKIMDVAEDLVVPMMDQPIRVDRDALTLGYAGVYSSFLLFAQRAEKKYGV 306 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVAS 345 PA +L G+R +GGQED + D+AL++ R +++ +V++ Sbjct: 307 PARDILVELGRRGTVGGQEDMIEDLALDMSRARQNQKVSA 346 >tr|C8CEC4|C8CEC4_PSEAE Tax_Id=287 (nahM)SubName: Full=2-oxo-4-hydroxypentanoate aldolase;[Pseudomonas aeruginosa] Length = 346 Score = 342 bits (878), Expect = 3e-92 Identities = 166/340 (48%), Positives = 233/340 (68%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 +V + D SLRDG H KRHQ E++ A+ LDAAG+P+IE+THGDGLGG S NYGF Sbjct: 7 NVTLHDMSLRDGMHAKRHQISLEQMIAVATGLDAAGMPLIEITHGDGLGGRSINYGFPAH 66 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 ++E ++ K+AK++ L+LPG+GT + +K A D G S R+ATHCTEADVS QH G Sbjct: 67 SDEEYLRAVIPRLKQAKVSALLLPGIGTVDHLKMALDCGVSTIRVATHCTEADVSEQHIG 126 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 ++R+LG +TVGFLMMAH I+ EK+ QAR+M G C+Y DSAG ++ D V++++ L Sbjct: 127 MSRKLGADTVGFLMMAHMISAEKVLEQARLMESYGANCIYCTDSAGYMLPDEVSEKIGLL 186 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 AEL ++GFHGH N+G+ +ANS+ A+ AGA +IDGSV GAGAGN P+E + V Sbjct: 187 RAELNPATEIGFHGHHNMGMAIANSLAAIEAGASRIDGSVAGLGAGAGNTPLEVFVAVCK 246 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 ++GV+TG ED+V P M +DR+AL +GY+GVYSSFL A R ++YGV Sbjct: 247 RMGVETGIDLYKIMDVAEDLVVPMMDQPIRVDRDALTLGYAGVYSSFLLFAQRAEKKYGV 306 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVAS 345 PA +L G+R +GGQED + D+AL++ R +++ +V++ Sbjct: 307 PARDILVELGRRGTVGGQEDMIEDLALDMSRARQNQKVSA 346 >tr|Q84I97|Q84I97_9PSED Tax_Id=115714 (xylK)SubName: Full=2-oxo-4-hydroxy pentanoate aldolase;[Pseudomonas sp. S-47] Length = 346 Score = 342 bits (877), Expect = 4e-92 Identities = 165/340 (48%), Positives = 233/340 (68%) Query: 6 DVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65 +V + D SLRDG H KRHQ E++ A+ LDAAG+P+IE+THGDGLGG S NYGF Sbjct: 7 NVTLHDMSLRDGMHAKRHQISLEQMIAVATGLDAAGMPLIEITHGDGLGGRSINYGFPAH 66 Query: 66 PEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQHFG 125 ++E ++ K+AK++ L+LPG+GT + +K A D G S R+ATHCTEADVS QH G Sbjct: 67 SDEEYLRAVIPRLKQAKVSALLLPGIGTVDHLKMALDCGVSTIRVATHCTEADVSEQHIG 126 Query: 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVAAL 185 ++R+LG +TVGFLMMAH I+ EK+ QAR+M G C+Y DSAG ++ D V++++ L Sbjct: 127 MSRKLGADTVGFLMMAHMISAEKVLEQARLMESYGANCIYCTDSAGYMLPDEVSEKIGLL 186 Query: 186 VAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGVFD 245 AEL ++GFHGH N+G+ +ANS+ A+ AGA +IDGSV GAGAGN P+E + V Sbjct: 187 RAELNPATEIGFHGHHNMGMAIANSLAAIEAGASRIDGSVAGLGAGAGNTPLEVFVAVCK 246 Query: 246 KIGVKTGXXXXXXXXXXEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERYGV 305 ++GV+TG ED+V P M +DR+AL +GY+GVYSSFL A R ++YG+ Sbjct: 247 RMGVETGIDLYKIMDVAEDLVVPMMDQPIRVDRDALTLGYAGVYSSFLLFAQRAEKKYGI 306 Query: 306 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGQVAS 345 PA +L G+R +GGQED + D+AL++ R +++ +V++ Sbjct: 307 PARDILVELGRRGTVGGQEDMIEDLALDMSRARQNQKVSA 346 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.319 0.135 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 2,422,835,336 Number of extensions: 97330718 Number of successful extensions: 277236 Number of sequences better than 10.0: 3726 Number of HSP's gapped: 278021 Number of HSP's successfully gapped: 3730 Length of query: 347 Length of database: 3,846,993,858 Length adjustment: 138 Effective length of query: 209 Effective length of database: 2,291,015,844 Effective search space: 478822311396 Effective search space used: 478822311396 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 81 (35.8 bits)