BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MMAR_5081
         (165 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,275,203 sequences; 3,846,993,858 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|B2HJ22|ISPF_MYCMM Tax_Id=216594 (ispF)RecName: Full=2-C-methy...   293   5e-78
tr|A0PV28|A0PV28_MYCUA Tax_Id=362242 (ispF)RecName: Full=2-C-met...   280   3e-74
sp|P65183|ISPF_MYCTU Tax_Id=1773 (ispF)RecName: Full=2-C-methyl-...   258   1e-67
sp|A5U8Q6|ISPF_MYCTA Tax_Id=419947 (ispF)RecName: Full=2-C-methy...   258   1e-67
sp|C1AI40|ISPF_MYCBT Tax_Id=561275 (ispF)RecName: Full=2-C-methy...   258   1e-67
sp|A1KPR7|ISPF_MYCBP Tax_Id=410289 (ispF)RecName: Full=2-C-methy...   258   1e-67
sp|P65184|ISPF_MYCBO Tax_Id=1765 (ispF)RecName: Full=2-C-methyl-...   258   1e-67
tr|C6DMN3|C6DMN3_MYCTK Tax_Id=478434 RecName: Full=2-C-methyl-D-...   258   1e-67
tr|A5WTF0|A5WTF0_MYCTF Tax_Id=336982 RecName: Full=2-C-methyl-D-...   258   1e-67
tr|A4KM66|A4KM66_MYCTU Tax_Id=395095 RecName: Full=2-C-methyl-D-...   258   1e-67
tr|A2VPY9|A2VPY9_MYCTU Tax_Id=348776 RecName: Full=2-C-methyl-D-...   258   1e-67
sp|Q743W4|ISPF_MYCPA Tax_Id=1770 (ispF)RecName: Full=2-C-methyl-...   217   3e-55
sp|A0QAB4|ISPF_MYCA1 Tax_Id=243243 (ispF)RecName: Full=2-C-methy...   217   3e-55
sp|Q9CCW5|ISPF_MYCLE Tax_Id=1769 (ispF)RecName: Full=2-C-methyl-...   216   6e-55
sp|B8ZUA8|ISPF_MYCLB Tax_Id=561304 (ispF)RecName: Full=2-C-methy...   216   6e-55
tr|A3Q6W1|A3Q6W1_MYCSJ Tax_Id=164757 RecName: Full=2-C-methyl-D-...   207   2e-52
tr|Q1B2P2|Q1B2P2_MYCSS Tax_Id=164756 RecName: Full=2-C-methyl-D-...   206   9e-52
tr|A1UMF6|A1UMF6_MYCSK Tax_Id=189918 RecName: Full=2-C-methyl-D-...   206   9e-52
sp|A1TG10|ISPF_MYCVP Tax_Id=350058 (ispF)RecName: Full=2-C-methy...   204   3e-51
sp|B1MGY4|ISPF_MYCA9 Tax_Id=561007 (ispF)RecName: Full=2-C-methy...   201   2e-50
tr|A4T5L7|A4T5L7_MYCGI Tax_Id=350054 RecName: Full=2-C-methyl-D-...   196   7e-49
tr|C3JUN0|C3JUN0_RHOER Tax_Id=596309 (ispF)RecName: Full=2-C-met...   193   5e-48
sp|C0ZPR8|ISPF_RHOE4 Tax_Id=234621 (ispF)RecName: Full=2-C-methy...   192   8e-48
tr|A0R559|A0R559_MYCS2 Tax_Id=246196 (ispF)RecName: Full=2-C-met...   191   3e-47
sp|C1BAC3|ISPF_RHOOB Tax_Id=632772 (ispF)RecName: Full=2-C-methy...   188   2e-46
sp|Q5Z2R2|ISPF_NOCFA Tax_Id=37329 (ispF)RecName: Full=2-C-methyl...   187   2e-46
tr|C7MQ49|C7MQ49_SACVD Tax_Id=471857 RecName: Full=2-C-methyl-D-...   187   3e-46
sp|Q0S889|ISPF_RHOSR Tax_Id=101510 (ispF)RecName: Full=2-C-methy...   187   4e-46
tr|A4F6W4|A4F6W4_SACEN Tax_Id=405948 (ispF)RecName: Full=2-C-met...   186   9e-46
tr|C0U9Y4|C0U9Y4_9ACTO Tax_Id=526225 RecName: Full=2-C-methyl-D-...   184   4e-45
tr|C6WGL5|C6WGL5_ACTMD Tax_Id=446462 RecName: Full=2-C-methyl-D-...   183   6e-45
tr|C8XAB3|C8XAB3_NAKMY Tax_Id=479431 SubName: Full=2-C-methyl-D-...   181   2e-44
tr|D0L459|D0L459_GORB4 Tax_Id=526226 SubName: Full=2C-methyl-D-e...   175   1e-42
tr|D1A5D7|D1A5D7_THECU Tax_Id=471852 SubName: Full=2C-methyl-D-e...   171   2e-41
tr|C4RE02|C4RE02_9ACTO Tax_Id=219305 RecName: Full=2-C-methyl-D-...   166   1e-39
sp|A8M7S7|ISPF_SALAI Tax_Id=391037 (ispF)RecName: Full=2-C-methy...   164   2e-39
sp|A6W6E9|ISPF_KINRD Tax_Id=266940 (ispF)RecName: Full=2-C-methy...   164   2e-39
sp|A8LF85|ISPF_FRASN Tax_Id=298653 (ispF)RecName: Full=2-C-methy...   164   2e-39
sp|A4XCN1|ISPF_SALTO Tax_Id=369723 (ispF)RecName: Full=2-C-methy...   164   3e-39
tr|C3PJB9|C3PJB9_CORA7 Tax_Id=548476 (ispF)RecName: Full=2-C-met...   162   1e-38
sp|Q8NMB9|ISPF_CORGL Tax_Id=1718 (ispF)RecName: Full=2-C-methyl-...   161   2e-38
tr|C0WGV4|C0WGV4_9CORY Tax_Id=525260 (ispF)RecName: Full=2-C-met...   160   6e-38
sp|Q6NFC2|ISPF_CORDI Tax_Id=1717 (ispF)RecName: Full=2-C-methyl-...   159   7e-38
tr|C2CS56|C2CS56_CORST Tax_Id=525268 (ispF)RecName: Full=2-C-met...   159   1e-37
tr|C6RCC8|C6RCC8_9CORY Tax_Id=553206 (ispF)RecName: Full=2-C-met...   158   2e-37
sp|B1VIQ0|ISPF_CORU7 Tax_Id=504474 (ispF)RecName: Full=2-C-methy...   157   3e-37
tr|C2BMC6|C2BMC6_9CORY Tax_Id=525264 (ispF)RecName: Full=2-C-met...   157   3e-37
tr|B5GP17|B5GP17_STRCL Tax_Id=443255 RecName: Full=2-C-methyl-D-...   157   4e-37
sp|Q4JXJ6|ISPF_CORJK Tax_Id=306537 (ispF)RecName: Full=2-C-methy...   156   8e-37
sp|Q0RBN8|ISPF_FRAAA Tax_Id=326424 (ispF)RecName: Full=2-C-methy...   155   1e-36

>sp|B2HJ22|ISPF_MYCMM Tax_Id=216594 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium marinum]
          Length = 165

 Score =  293 bits (749), Expect = 5e-78
 Identities = 146/165 (88%), Positives = 147/165 (89%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +NGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD
Sbjct: 1   MNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL
Sbjct: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLRDPLGSQ 165
           SRLLNAPVSVS                  IATALVVSLRDPLGSQ
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLRDPLGSQ 165


>tr|A0PV28|A0PV28_MYCUA Tax_Id=362242 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium ulcerans]
          Length = 159

 Score =  280 bits (717), Expect = 3e-74
 Identities = 140/159 (88%), Positives = 141/159 (88%)

Query: 7   VGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVFG 66
           +GLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVFG
Sbjct: 1   MGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVFG 60

Query: 67  VGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLNA 126
           VGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLNA
Sbjct: 61  VGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLNA 120

Query: 127 PVSVSXXXXXXXXXXXXXXXXXXIATALVVSLRDPLGSQ 165
           PVSVS                  IATALVVSLRDPLGSQ
Sbjct: 121 PVSVSATTTDGLGLTGRGEGLAAIATALVVSLRDPLGSQ 159


>sp|P65183|ISPF_MYCTU Tax_Id=1773 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  258 bits (659), Expect = 1e-67
 Identities = 129/159 (81%), Positives = 133/159 (83%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVGLG DVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVA HALCDAVLSAAGLGD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IG+VFGV DPRW+GVSGA MLRHVV LITQHGYRVGNA VQV+GNRPKIGWRR EAQAVL
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLR 159
           SRLLNAPVSVS                  IATALVVSLR
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR 159


>sp|A5U8Q6|ISPF_MYCTA Tax_Id=419947 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  258 bits (659), Expect = 1e-67
 Identities = 129/159 (81%), Positives = 133/159 (83%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVGLG DVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVA HALCDAVLSAAGLGD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IG+VFGV DPRW+GVSGA MLRHVV LITQHGYRVGNA VQV+GNRPKIGWRR EAQAVL
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLR 159
           SRLLNAPVSVS                  IATALVVSLR
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR 159


>sp|C1AI40|ISPF_MYCBT Tax_Id=561275 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium bovis]
          Length = 159

 Score =  258 bits (659), Expect = 1e-67
 Identities = 129/159 (81%), Positives = 133/159 (83%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVGLG DVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVA HALCDAVLSAAGLGD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IG+VFGV DPRW+GVSGA MLRHVV LITQHGYRVGNA VQV+GNRPKIGWRR EAQAVL
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLR 159
           SRLLNAPVSVS                  IATALVVSLR
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR 159


>sp|A1KPR7|ISPF_MYCBP Tax_Id=410289 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium bovis]
          Length = 159

 Score =  258 bits (659), Expect = 1e-67
 Identities = 129/159 (81%), Positives = 133/159 (83%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVGLG DVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVA HALCDAVLSAAGLGD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IG+VFGV DPRW+GVSGA MLRHVV LITQHGYRVGNA VQV+GNRPKIGWRR EAQAVL
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLR 159
           SRLLNAPVSVS                  IATALVVSLR
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR 159


>sp|P65184|ISPF_MYCBO Tax_Id=1765 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium bovis]
          Length = 159

 Score =  258 bits (659), Expect = 1e-67
 Identities = 129/159 (81%), Positives = 133/159 (83%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVGLG DVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVA HALCDAVLSAAGLGD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IG+VFGV DPRW+GVSGA MLRHVV LITQHGYRVGNA VQV+GNRPKIGWRR EAQAVL
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLR 159
           SRLLNAPVSVS                  IATALVVSLR
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR 159


>tr|C6DMN3|C6DMN3_MYCTK Tax_Id=478434 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  258 bits (659), Expect = 1e-67
 Identities = 129/159 (81%), Positives = 133/159 (83%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVGLG DVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVA HALCDAVLSAAGLGD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IG+VFGV DPRW+GVSGA MLRHVV LITQHGYRVGNA VQV+GNRPKIGWRR EAQAVL
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLR 159
           SRLLNAPVSVS                  IATALVVSLR
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR 159


>tr|A5WTF0|A5WTF0_MYCTF Tax_Id=336982 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  258 bits (659), Expect = 1e-67
 Identities = 129/159 (81%), Positives = 133/159 (83%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVGLG DVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVA HALCDAVLSAAGLGD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IG+VFGV DPRW+GVSGA MLRHVV LITQHGYRVGNA VQV+GNRPKIGWRR EAQAVL
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLR 159
           SRLLNAPVSVS                  IATALVVSLR
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR 159


>tr|A4KM66|A4KM66_MYCTU Tax_Id=395095 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium tuberculosis str.
           Haarlem]
          Length = 159

 Score =  258 bits (659), Expect = 1e-67
 Identities = 129/159 (81%), Positives = 133/159 (83%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVGLG DVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVA HALCDAVLSAAGLGD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IG+VFGV DPRW+GVSGA MLRHVV LITQHGYRVGNA VQV+GNRPKIGWRR EAQAVL
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLR 159
           SRLLNAPVSVS                  IATALVVSLR
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR 159


>tr|A2VPY9|A2VPY9_MYCTU Tax_Id=348776 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium tuberculosis C]
          Length = 159

 Score =  258 bits (659), Expect = 1e-67
 Identities = 129/159 (81%), Positives = 133/159 (83%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVGLG DVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVA HALCDAVLSAAGLGD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           IG+VFGV DPRW+GVSGA MLRHVV LITQHGYRVGNA VQV+GNRPKIGWRR EAQAVL
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLR 159
           SRLLNAPVSVS                  IATALVVSLR
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR 159


>sp|Q743W4|ISPF_MYCPA Tax_Id=1770 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium paratuberculosis]
          Length = 159

 Score =  217 bits (553), Expect = 3e-55
 Identities = 108/156 (69%), Positives = 120/156 (76%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N  PR+GLGVDVHPI+PGRPC L+GLLF  ADGCAGHSDGDV AHALCDAVLSAAGLGD
Sbjct: 1   MNTTPRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           +G VFGV DPRW GVSGA MLRHV +L  +HG+RVGNA+VQV+GNRPK+G RR EAQ VL
Sbjct: 61  VGAVFGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           S LL APVSV+                  IATALVV
Sbjct: 121 SELLGAPVSVAATTTDGLGLTGRGEGLAAIATALVV 156


>sp|A0QAB4|ISPF_MYCA1 Tax_Id=243243 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium avium]
          Length = 159

 Score =  217 bits (553), Expect = 3e-55
 Identities = 108/156 (69%), Positives = 120/156 (76%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N  PR+GLGVDVHPI+PGRPC L+GLLF  ADGCAGHSDGDV AHALCDAVLSAAGLGD
Sbjct: 1   MNTTPRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           +G VFGV DPRW GVSGA MLRHV +L  +HG+RVGNA+VQV+GNRPK+G RR EAQ VL
Sbjct: 61  VGAVFGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           S LL APVSV+                  IATALVV
Sbjct: 121 SELLGAPVSVAATTTDGLGLTGRGEGLAAIATALVV 156


>sp|Q9CCW5|ISPF_MYCLE Tax_Id=1769 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium leprae]
          Length = 158

 Score =  216 bits (550), Expect = 6e-55
 Identities = 110/155 (70%), Positives = 117/155 (75%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVA HALCDAVLSAAG GDIG 
Sbjct: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           +F VGDPRWE VSGA MLRHVVEL+ +HGY V NASVQV+GNRPKIG RR EAQ +LS L
Sbjct: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSL 158
           L APVSV+                  IATALVV +
Sbjct: 124 LRAPVSVAATTTEGLGLTGRGEGLSAIATALVVQV 158


>sp|B8ZUA8|ISPF_MYCLB Tax_Id=561304 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium leprae]
          Length = 158

 Score =  216 bits (550), Expect = 6e-55
 Identities = 110/155 (70%), Positives = 117/155 (75%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVA HALCDAVLSAAG GDIG 
Sbjct: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           +F VGDPRWE VSGA MLRHVVEL+ +HGY V NASVQV+GNRPKIG RR EAQ +LS L
Sbjct: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSL 158
           L APVSV+                  IATALVV +
Sbjct: 124 LRAPVSVAATTTEGLGLTGRGEGLSAIATALVVQV 158


>tr|A3Q6W1|A3Q6W1_MYCSJ Tax_Id=164757 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium sp.]
          Length = 158

 Score =  207 bits (528), Expect = 2e-52
 Identities = 106/153 (69%), Positives = 116/153 (75%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LPRVGLG DVHPIEPGRPC L+GL F  ADGCAGHSDGDVAAHALCDA+LSAAGLGD+G 
Sbjct: 3   LPRVGLGTDVHPIEPGRPCRLLGLHFDGADGCAGHSDGDVAAHALCDALLSAAGLGDLGG 62

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           VFG G P WEGVSGA MLRHV  L+ + G+RVGNA+VQV+GNRPKIG RR EAQ +LS L
Sbjct: 63  VFGTGRPEWEGVSGADMLRHVRGLLQEAGFRVGNATVQVIGNRPKIGPRRAEAQELLSEL 122

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           + APVSVS                  IATALVV
Sbjct: 123 IGAPVSVSATTTDGLGLTGRGEGLAAIATALVV 155


>tr|Q1B2P2|Q1B2P2_MYCSS Tax_Id=164756 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium sp.]
          Length = 158

 Score =  206 bits (523), Expect = 9e-52
 Identities = 105/153 (68%), Positives = 115/153 (75%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LPRVGLG DVHPIEPGRPC L+GL F   DGCAGHSDGDVAAHALCDA+LSAAGLGD+G 
Sbjct: 3   LPRVGLGTDVHPIEPGRPCRLLGLHFDGEDGCAGHSDGDVAAHALCDALLSAAGLGDLGG 62

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           VFG G P WEGVSGA MLRHV  L+ + G+RVGNA+VQV+GNRPKIG RR EAQ +LS L
Sbjct: 63  VFGTGRPEWEGVSGADMLRHVRGLLQEAGFRVGNATVQVIGNRPKIGPRRAEAQELLSEL 122

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           + APVSVS                  IATALVV
Sbjct: 123 IGAPVSVSATTTDGLGLTGRGEGLAAIATALVV 155


>tr|A1UMF6|A1UMF6_MYCSK Tax_Id=189918 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium sp.]
          Length = 158

 Score =  206 bits (523), Expect = 9e-52
 Identities = 105/153 (68%), Positives = 115/153 (75%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LPRVGLG DVHPIEPGRPC L+GL F   DGCAGHSDGDVAAHALCDA+LSAAGLGD+G 
Sbjct: 3   LPRVGLGTDVHPIEPGRPCRLLGLHFDGEDGCAGHSDGDVAAHALCDALLSAAGLGDLGG 62

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           VFG G P WEGVSGA MLRHV  L+ + G+RVGNA+VQV+GNRPKIG RR EAQ +LS L
Sbjct: 63  VFGTGRPEWEGVSGADMLRHVRGLLQEAGFRVGNATVQVIGNRPKIGPRRAEAQELLSEL 122

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           + APVSVS                  IATALVV
Sbjct: 123 IGAPVSVSATTTDGLGLTGRGEGLAAIATALVV 155


>sp|A1TG10|ISPF_MYCVP Tax_Id=350058 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium vanbaalenii]
          Length = 162

 Score =  204 bits (519), Expect = 3e-51
 Identities = 104/151 (68%), Positives = 114/151 (75%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVGLG DVHPIE GRPCWL+ LLF  ADGCAGHSDGDVAAHALCDA+LSAAG+GDIG+VF
Sbjct: 6   RVGLGTDVHPIEAGRPCWLLCLLFDDADGCAGHSDGDVAAHALCDALLSAAGMGDIGEVF 65

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G G P+W GVSGA MLRHV  ++T  G RVGNA+VQV+GNRPKIG RR EAQ VLS +L 
Sbjct: 66  GTGLPQWRGVSGADMLRHVHSMMTAEGLRVGNAAVQVIGNRPKIGPRRAEAQRVLSGILG 125

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           APVSVS                  IATALVV
Sbjct: 126 APVSVSATTTDGLGLTGRGEGLAAIATALVV 156


>sp|B1MGY4|ISPF_MYCA9 Tax_Id=561007 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium abscessus]
          Length = 158

 Score =  201 bits (512), Expect = 2e-50
 Identities = 97/158 (61%), Positives = 117/158 (74%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGD 60
           +N LPRVG+G DVHPIE G+PCWL+GLLF   +GC GHSDGDVAAHALCDA+LSAAGLGD
Sbjct: 1   MNALPRVGIGTDVHPIEEGKPCWLLGLLFSDENGCEGHSDGDVAAHALCDALLSAAGLGD 60

Query: 61  IGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVL 120
           +G VFG G P W GVSGA ML HV +L+  +G+++GNA+VQV+GNRPK+G RR EAQ +L
Sbjct: 61  VGAVFGTGRPEWTGVSGAKMLSHVRDLLHDNGFQIGNAAVQVIGNRPKVGPRRAEAQELL 120

Query: 121 SRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSL 158
           S L+ APVSVS                  +ATALV +L
Sbjct: 121 SGLIGAPVSVSATTTDGLGLTGRGEGLAAVATALVTAL 158


>tr|A4T5L7|A4T5L7_MYCGI Tax_Id=350054 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium gilvum]
          Length = 160

 Score =  196 bits (498), Expect = 7e-49
 Identities = 100/155 (64%), Positives = 115/155 (74%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVGLG DVHPIE GRPC L+ LLF   DGCAGHSDGDVAAHALCDA+LSAAG+GDIG+VF
Sbjct: 5   RVGLGTDVHPIEAGRPCRLLCLLFDDGDGCAGHSDGDVAAHALCDALLSAAGMGDIGEVF 64

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G G P+W  VSGA MLRHV  L+ + G++VGNA+VQV+GNRPKIG RR EAQ +LS LL+
Sbjct: 65  GTGLPQWRDVSGADMLRHVHTLLVEQGFQVGNAAVQVIGNRPKIGPRRAEAQRILSELLD 124

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALVVSLRD 160
           APVSVS                  IATALV++  D
Sbjct: 125 APVSVSATTTDGLGLTGRGEGLAAIATALVLAPAD 159


>tr|C3JUN0|C3JUN0_RHOER Tax_Id=596309 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Rhodococcus erythropolis SK121]
          Length = 158

 Score =  193 bits (491), Expect = 5e-48
 Identities = 96/152 (63%), Positives = 111/152 (73%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVGLG DVHPIE GRPCW+ GLLF  ADGC+GHSDGDVA HALCDA+LSAAGLGD+G VF
Sbjct: 2   RVGLGTDVHPIEVGRPCWMAGLLFEEADGCSGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G G P W+GVSGA ML  V  L+ ++ + VGNA+VQV+GNRPKIG RR EAQ VLS +L 
Sbjct: 62  GTGRPEWDGVSGARMLAEVRRLLEENQFAVGNAAVQVIGNRPKIGPRRDEAQKVLSEILG 121

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALVVS 157
           APVSVS                  +ATALV++
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAMATALVMT 153


>sp|C0ZPR8|ISPF_RHOE4 Tax_Id=234621 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Rhodococcus erythropolis]
          Length = 158

 Score =  192 bits (489), Expect = 8e-48
 Identities = 96/152 (63%), Positives = 111/152 (73%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVGLG DVHPIE GRPCW+ GLLF  ADGC+GHSDGDVA HALCDA+LSAAGLGD+G VF
Sbjct: 2   RVGLGTDVHPIEVGRPCWMAGLLFEEADGCSGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G G P W+GVSGA ML  V  L+ ++ + VGNA+VQV+GNRPKIG RR EAQ VLS +L 
Sbjct: 62  GTGRPEWDGVSGARMLAEVRRLLEENQFTVGNAAVQVIGNRPKIGPRRGEAQKVLSDILG 121

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALVVS 157
           APVSVS                  +ATALV++
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAMATALVMT 153


>tr|A0R559|A0R559_MYCS2 Tax_Id=246196 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium smegmatis]
          Length = 163

 Score =  191 bits (484), Expect = 3e-47
 Identities = 98/160 (61%), Positives = 114/160 (71%), Gaps = 2/160 (1%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LPRVGLG DVHPIE GRPC L+ L F  ADGCAGHSDGDVAAHALCDA+LSAAGLGD+G 
Sbjct: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHALCDALLSAAGLGDLGT 62

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           +FG   P+W G SGA M+RHV  L+   G+ +GNA+VQV+GNRPK+G RR EAQ VLS L
Sbjct: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLRDPLG 163
           + APVSVS                  IATALV +  +P+G
Sbjct: 123 VGAPVSVSATTTDGLGLTGRGEGLAAIATALVAA--EPVG 160


>sp|C1BAC3|ISPF_RHOOB Tax_Id=632772 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Rhodococcus opacus]
          Length = 158

 Score =  188 bits (477), Expect = 2e-46
 Identities = 94/151 (62%), Positives = 106/151 (70%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVG+G DVHPIE GRPCW+ GLLF   +GCAGHSDGDVA HALCDA+LSAAGLGD+G VF
Sbjct: 2   RVGIGTDVHPIEQGRPCWMAGLLFEDENGCAGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G G P W GVSGA ML  V  L+ Q  + V NA+VQV+GNRPKIG RR EAQ VLS +L 
Sbjct: 62  GTGRPEWSGVSGAAMLAEVRRLLEQDDFGVANAAVQVIGNRPKIGPRRNEAQKVLSDILG 121

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           APVSVS                  +ATALV+
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAMATALVI 152


>sp|Q5Z2R2|ISPF_NOCFA Tax_Id=37329 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Nocardia farcinica]
          Length = 155

 Score =  187 bits (476), Expect = 2e-46
 Identities = 94/150 (62%), Positives = 107/150 (71%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVG+G DVHPIEPGRPCW+ GLLF   DGC+GHSDGDVAAHALCDA+LSAAGLGD+G VF
Sbjct: 2   RVGIGSDVHPIEPGRPCWMAGLLFEGEDGCSGHSDGDVAAHALCDALLSAAGLGDVGAVF 61

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G G P W  VSGA ML  V  L+ + G+ V NA+VQV+GNRPKIG RR EAQ VL  LL+
Sbjct: 62  GTGRPEWADVSGAAMLTEVRRLLGEAGFEVVNAAVQVIGNRPKIGPRRAEAQRVLGDLLD 121

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           APVSVS                  +ATAL+
Sbjct: 122 APVSVSGTTTDGLGLTGRGEGIAAVATALL 151


>tr|C7MQ49|C7MQ49_SACVD Tax_Id=471857 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Saccharomonospora viridis]
          Length = 157

 Score =  187 bits (475), Expect = 3e-46
 Identities = 94/155 (60%), Positives = 108/155 (69%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           R+G GVDVHPIEPGR CWL GL +P ADGC+GHSDGDVA+HALCDA+LSAAGLGD+G VF
Sbjct: 2   RIGQGVDVHPIEPGRECWLAGLHWPDADGCSGHSDGDVASHALCDALLSAAGLGDLGAVF 61

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G G  +W G  G  +L  V   +T+ GYRVGNA VQV+GNRPKIG RR EAQ VLS  + 
Sbjct: 62  GTGQNQWAGAHGVELLAEVRTRVTEAGYRVGNAVVQVIGNRPKIGRRREEAQRVLSEAVG 121

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALVVSLRD 160
           APVSVS                  IATAL+V L +
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAIATALLVPLAE 156


>sp|Q0S889|ISPF_RHOSR Tax_Id=101510 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Rhodococcus sp.]
          Length = 158

 Score =  187 bits (474), Expect = 4e-46
 Identities = 93/151 (61%), Positives = 106/151 (70%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVG+G DVHPIE GRPCW+ GLLF   +GCAGHSDGDVA HALCDA+LSAAGLGD+G VF
Sbjct: 2   RVGIGTDVHPIEQGRPCWMAGLLFEDENGCAGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G G P W GVSGA ML  V  L+ +  + V NA+VQV+GNRPKIG RR EAQ VLS +L 
Sbjct: 62  GTGRPEWSGVSGAAMLAEVRRLLEEDDFDVANAAVQVIGNRPKIGPRRNEAQKVLSDILG 121

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           APVSVS                  +ATALV+
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAMATALVI 152


>tr|A4F6W4|A4F6W4_SACEN Tax_Id=405948 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Saccharopolyspora erythraea]
          Length = 158

 Score =  186 bits (471), Expect = 9e-46
 Identities = 90/152 (59%), Positives = 107/152 (70%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PR+G GVDVHP+E GR CW+ GLL+P  DGCAGHSDGDVA+HALCDA+LSAAGLGD+G 
Sbjct: 2   IPRIGQGVDVHPVEAGRECWVAGLLWPGEDGCAGHSDGDVASHALCDALLSAAGLGDLGA 61

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           VFG GD RW G  GA +L      +T+ G+ +GNA VQVVGNRP+IG RR EAQ VLS +
Sbjct: 62  VFGTGDDRWAGAHGAELLTEARRRVTEAGFGIGNAVVQVVGNRPRIGKRREEAQRVLSEV 121

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           + APVSVS                  +ATALV
Sbjct: 122 VGAPVSVSGTTTDGLGLTGRGEGIAAVATALV 153


>tr|C0U9Y4|C0U9Y4_9ACTO Tax_Id=526225 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Geodermatophilus obscurus DSM
           43160]
          Length = 167

 Score =  184 bits (466), Expect = 4e-45
 Identities = 92/153 (60%), Positives = 107/153 (69%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LPRVG+GVDVHP+  GR CWL GL +P  DGCAGHSDGDV AHAL DAVLSAAGLGDIG 
Sbjct: 5   LPRVGVGVDVHPVAAGRTCWLAGLQWPGVDGCAGHSDGDVVAHALTDAVLSAAGLGDIGG 64

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           + G  DPRW G  GA +L HV E++   G++VGNA+VQ+VGN PK+G RR EA+ VLSR 
Sbjct: 65  LLGTDDPRWAGARGAAVLAHVREVLETAGWQVGNAAVQLVGNTPKVGPRRAEAEQVLSRA 124

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           L APVSV+                  +ATALVV
Sbjct: 125 LGAPVSVTATTTDGLGLTGRGEGRAAMATALVV 157


>tr|C6WGL5|C6WGL5_ACTMD Tax_Id=446462 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Actinosynnema mirum]
          Length = 155

 Score =  183 bits (464), Expect = 6e-45
 Identities = 88/151 (58%), Positives = 104/151 (68%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVG+G DVHP+EPGR CW+VGLL+  ADGCAGHSDGDVAAHALCDA+LSAAGLGD+G VF
Sbjct: 2   RVGIGTDVHPVEPGRDCWMVGLLWEGADGCAGHSDGDVAAHALCDALLSAAGLGDLGAVF 61

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G  DPRW G  G   L     L+   G+ VGNA+VQV+GN P++G RR EAQ VLS +L 
Sbjct: 62  GTSDPRWSGAHGVEFLAEARRLVEAEGFVVGNAAVQVIGNAPRVGKRRAEAQKVLSEVLG 121

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
            PVSVS                  +ATAL++
Sbjct: 122 GPVSVSGTTTDGLGLTGRGEGVAAVATALLL 152


>tr|C8XAB3|C8XAB3_NAKMY Tax_Id=479431 SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Nakamurella multipartita]
          Length = 381

 Score =  181 bits (459), Expect = 2e-44
 Identities = 86/126 (68%), Positives = 98/126 (77%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVG G+DVHPIEPGR CW+ GLLF  ADGCAGHSDGDVAAHALCDA+LSAAGLGD+G VF
Sbjct: 229 RVGSGIDVHPIEPGRDCWVAGLLFEDADGCAGHSDGDVAAHALCDALLSAAGLGDLGAVF 288

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G  DPRW G SGAT+L  VV  +   GY+V NASVQV+ N PK+  RR EAQ  LS ++ 
Sbjct: 289 GTSDPRWSGASGATLLAEVVARVKAAGYQVINASVQVIANTPKLSPRRVEAQQALSAVVG 348

Query: 126 APVSVS 131
            PVSV+
Sbjct: 349 GPVSVA 354


>tr|D0L459|D0L459_GORB4 Tax_Id=526226 SubName:
           Full=2C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Gordonia bronchialis]
          Length = 152

 Score =  175 bits (444), Expect = 1e-42
 Identities = 87/150 (58%), Positives = 98/150 (65%)

Query: 6   RVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           RVG+G D H ++    CW+VGL FP   GCAGHSDGDV AHALCDAVLSAAGLGD+G VF
Sbjct: 2   RVGIGTDAHRVDENCDCWMVGLHFPDTPGCAGHSDGDVGAHALCDAVLSAAGLGDVGSVF 61

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLN 125
           G G P W GVSG  ML HV  L+   G+ V N +VQV+GNRPKIG RR EAQ VLS  L 
Sbjct: 62  GTGRPEWAGVSGVAMLAHVATLVADAGFTVVNGAVQVIGNRPKIGPRRDEAQQVLSEALG 121

Query: 126 APVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           APVSVS                  +ATAL+
Sbjct: 122 APVSVSATTTDGLGMTGRGEGVAAVATALI 151


>tr|D1A5D7|D1A5D7_THECU Tax_Id=471852 SubName:
           Full=2C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Thermomonospora curvata DSM
           43183]
          Length = 156

 Score =  171 bits (434), Expect = 2e-41
 Identities = 87/152 (57%), Positives = 102/152 (67%), Gaps = 2/152 (1%)

Query: 7   VGLGVDVHPIEPGRPCWLVGLLFPS-ADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVF 65
           +G+G DVHP   GRP W+ GLL+P   DG  GHSDGDVAAHA CDA+LSAAGLGD+G VF
Sbjct: 1   MGVGTDVHPFGSGRPLWVAGLLWPDEGDGLTGHSDGDVAAHAACDALLSAAGLGDLGAVF 60

Query: 66  GVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLL- 124
           G  DPRW G SG  +L  V  L+T+HGY +GN ++QV+GNRPKIG RR EA+ VLS  L 
Sbjct: 61  GTADPRWRGASGTELLAEVARLLTEHGYAIGNVAIQVIGNRPKIGRRRAEAEKVLSEALG 120

Query: 125 NAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
            APVS+S                  IATALVV
Sbjct: 121 GAPVSLSATTTDGLGLTGRGEGLAAIATALVV 152


>tr|C4RE02|C4RE02_9ACTO Tax_Id=219305 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12; Flags: Fragment;[Micromonospora
           sp. ATCC 39149]
          Length = 220

 Score =  166 bits (419), Expect = 1e-39
 Identities = 82/152 (53%), Positives = 96/152 (63%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRV +G DVH  E GRPCWL GLL+P  DG AGHSD DV AHA C+A+LSAAGLGD+G 
Sbjct: 63  VPRVAIGTDVHAFEVGRPCWLAGLLWPGQDGLAGHSDADVVAHAACNALLSAAGLGDLGS 122

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
            FGV +P W G  G  +L      +   G+ +GN SVQVVGNRPKIG RR EA+AVLS  
Sbjct: 123 NFGVAEPEWAGAPGVALLAETARRVRAAGFEIGNVSVQVVGNRPKIGPRRAEAEAVLSEA 182

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           + APV+VS                  IA ALV
Sbjct: 183 VGAPVAVSAATTDGLGFTGRGEGLAGIAVALV 214


>sp|A8M7S7|ISPF_SALAI Tax_Id=391037 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Salinispora arenicola]
          Length = 161

 Score =  164 bits (416), Expect = 2e-39
 Identities = 83/157 (52%), Positives = 96/157 (61%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRV +GVD H  E GRPCW+ GL +P  DG AGHSD DVAAHA C+A+LSAA LGD+G 
Sbjct: 4   VPRVAIGVDTHAFESGRPCWVAGLHWPGQDGLAGHSDADVAAHAACNALLSAADLGDLGA 63

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
            FGVG P W G SG  +L      +   GY +GN SVQV+GNRPKIG RR EAQ VLS  
Sbjct: 64  NFGVGQPEWSGASGVALLTESASRVRAAGYAIGNVSVQVIGNRPKIGSRRAEAQRVLSGA 123

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVVSLRD 160
           + APVS+S                  IA ALV    D
Sbjct: 124 VGAPVSISAATTDGLGFPGRGEGLTGIAVALVYEAPD 160


>sp|A6W6E9|ISPF_KINRD Tax_Id=266940 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Kineococcus radiotolerans]
          Length = 159

 Score =  164 bits (416), Expect = 2e-39
 Identities = 86/157 (54%), Positives = 102/157 (64%), Gaps = 1/157 (0%)

Query: 1   VNGLPRVGLGVDVHPIEPGRPCWLVGLLFPS-ADGCAGHSDGDVAAHALCDAVLSAAGLG 59
           ++GLPRVG GVDVH +  GRPCW+ GLL+   A G  GHSDGDVAAHA CDA+ +AAGLG
Sbjct: 1   MSGLPRVGTGVDVHQLVAGRPCWVAGLLWEGEAAGPEGHSDGDVAAHACCDALFAAAGLG 60

Query: 60  DIGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAV 119
           D+G  FG   P + G SGA +L     L+ + G+ +GN SVQVVGNRPK+G RR EAQA 
Sbjct: 61  DLGAHFGTARPEFAGASGARLLAEAARLVREAGFEIGNVSVQVVGNRPKVGRRRAEAQAA 120

Query: 120 LSRLLNAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           LSR   APVSV+                  IATALVV
Sbjct: 121 LSRACGAPVSVAGTTTDALGLTGRGEGIAAIATALVV 157


>sp|A8LF85|ISPF_FRASN Tax_Id=298653 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Frankia sp.]
          Length = 160

 Score =  164 bits (416), Expect = 2e-39
 Identities = 80/152 (52%), Positives = 99/152 (65%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LPRVG GVDVHP E GR CW+  LL+P   G AGHSDGDVA+HA CDA+L+A+G+GD+G 
Sbjct: 6   LPRVGTGVDVHPFEQGRECWVACLLWPGETGLAGHSDGDVASHAACDALLTASGIGDLGA 65

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           VFG G P W G SGA +L     L+ + G+ +GN +VQVVGNRP++  RR EAQ  +S  
Sbjct: 66  VFGTGRPEWSGASGAALLGETARLLAEGGWLIGNVAVQVVGNRPRMAARRVEAQEAMSAA 125

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           L APV++S                  IATALV
Sbjct: 126 LGAPVNLSATTTDGLGLTGRGEGLAAIATALV 157


>sp|A4XCN1|ISPF_SALTO Tax_Id=369723 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Salinispora tropica]
          Length = 161

 Score =  164 bits (415), Expect = 3e-39
 Identities = 83/152 (54%), Positives = 96/152 (63%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRV +GVD+H  E GRPCW+ GL +P  DG AGHSD DVAAHA C+A+LSAA LGD+G 
Sbjct: 4   VPRVAIGVDMHAFESGRPCWVAGLHWPGQDGLAGHSDADVAAHAACNALLSAAELGDLGA 63

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
            FGVG P W G SG  +L      +   GY +GN SVQV+GNRPKIG RR EAQ VLS  
Sbjct: 64  NFGVGQPEWSGASGVALLSESARRVRTAGYTIGNVSVQVIGNRPKIGPRRAEAQQVLSAA 123

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           + APVSVS                  IA ALV
Sbjct: 124 VGAPVSVSAATTDGLGFPGRDEGLTGIAVALV 155


>tr|C3PJB9|C3PJB9_CORA7 Tax_Id=548476 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Corynebacterium aurimucosum]
          Length = 152

 Score =  162 bits (409), Expect = 1e-38
 Identities = 78/149 (52%), Positives = 100/149 (67%)

Query: 7   VGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVFG 66
           +G+  D H IEPG+PCW+ GLLF   DGC GHSDGDV +HAL DA+LSA+ LGD+G   G
Sbjct: 1   MGIATDAHQIEPGKPCWIAGLLFEDVDGCEGHSDGDVVSHALVDALLSASNLGDLGSFVG 60

Query: 67  VGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLNA 126
           VG P ++GVSGA +LR   EL+ + G+ +GNA+ Q+VG  PK+G RR EA+AVLS +L A
Sbjct: 61  VGRPEYDGVSGAQLLRECRELLEKEGFIIGNAAAQLVGQSPKMGPRRKEAEAVLSEILGA 120

Query: 127 PVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           PVSVS                  +ATA+V
Sbjct: 121 PVSVSATTTDHLGFTGRKEGRAAVATAVV 149


>sp|Q8NMB9|ISPF_CORGL Tax_Id=1718 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Corynebacterium glutamicum]
          Length = 160

 Score =  161 bits (407), Expect = 2e-38
 Identities = 76/152 (50%), Positives = 99/152 (65%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRVG+  D H IE G+PCW+  LLF   DGC GHSDGDV AHA+ DA+LSA+GLGD+G 
Sbjct: 6   IPRVGIATDAHQIEAGKPCWIACLLFEGVDGCEGHSDGDVVAHAIVDALLSASGLGDLGS 65

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
             GVG P ++GVSG  +L+ V EL++ HGY +GN + Q+VG  PK G RR EAQ V+S +
Sbjct: 66  FVGVGRPEYDGVSGTQLLKEVRELLSAHGYVIGNVAAQLVGQTPKFGPRREEAQQVISEI 125

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           + AP S+S                  +ATA+V
Sbjct: 126 IGAPCSLSATTTDHMGFTGRSEGRASVATAVV 157


>tr|C0WGV4|C0WGV4_9CORY Tax_Id=525260 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Corynebacterium accolens ATCC
           49725]
          Length = 162

 Score =  160 bits (404), Expect = 6e-38
 Identities = 78/152 (51%), Positives = 100/152 (65%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRVG+  D H IE G+PCW+ GLLF  A GC GHSDGDV AHAL DA+LSA+ LGD+G 
Sbjct: 6   IPRVGIATDAHQIEAGKPCWIAGLLFDDAPGCEGHSDGDVVAHALVDALLSASHLGDLGS 65

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
             GVG P ++GVSGA +LR   EL+   G+ +GNA+ Q++G  PK+G RR EA+AVLS +
Sbjct: 66  FVGVGRPEYDGVSGAQLLRECRELLEAEGFIIGNAAAQLIGQTPKMGPRREEAEAVLSEI 125

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           L A VS+S                  +ATA+V
Sbjct: 126 LGADVSISATTTDHLGFTGRKEGRAAVATAVV 157


>sp|Q6NFC2|ISPF_CORDI Tax_Id=1717 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Corynebacterium diphtheriae]
          Length = 160

 Score =  159 bits (403), Expect = 7e-38
 Identities = 78/152 (51%), Positives = 98/152 (64%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRVG+  D H IE G+PCW+  LLF  ADGC GHSDGDV AHAL DA+LSAA LGD+G 
Sbjct: 7   IPRVGIATDAHQIEAGKPCWIACLLFSGADGCEGHSDGDVVAHALVDALLSAANLGDLGS 66

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
             GVG   ++GVSG  +L    EL+  HG+ +GN +VQ+VG  PK+G RR EA+ V+S +
Sbjct: 67  FVGVGRKEYDGVSGTQLLTECRELLESHGFTIGNGAVQLVGQSPKMGPRREEAERVMSEI 126

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           L APVSVS                  +ATA+V
Sbjct: 127 LGAPVSVSATTTDHLGFTGRSEGRAAVATAVV 158


>tr|C2CS56|C2CS56_CORST Tax_Id=525268 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Corynebacterium striatum ATCC
           6940]
          Length = 160

 Score =  159 bits (401), Expect = 1e-37
 Identities = 77/152 (50%), Positives = 98/152 (64%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRVG+  D H IE G+PCW+ GLLF   DGC GHSDGDV +HAL DA+LSA+ LGD+G 
Sbjct: 6   IPRVGIATDAHQIEEGKPCWIAGLLFEGVDGCEGHSDGDVVSHALVDALLSASNLGDLGS 65

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
             GVG   ++ VSG  +LR   EL+  HG+ +GNA+ Q+VG  PK+G RR EA+ VLS +
Sbjct: 66  FVGVGRKEYDNVSGERLLRECRELLESHGFVIGNAAAQLVGQSPKMGPRREEAERVLSEI 125

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           L APVSVS                  +ATA+V
Sbjct: 126 LGAPVSVSATTTDHMGFTGRSEGRAAVATAVV 157


>tr|C6RCC8|C6RCC8_9CORY Tax_Id=553206 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Corynebacterium
           tuberculostearicum SK141]
          Length = 160

 Score =  158 bits (399), Expect = 2e-37
 Identities = 78/152 (51%), Positives = 99/152 (65%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRVG+  D H IE G+ CW+ GLLF    GC GHSDGDV AHAL DA+LSA+ LGD+G 
Sbjct: 6   IPRVGIATDAHQIEAGKDCWIAGLLFEGDAGCEGHSDGDVVAHALVDALLSASHLGDLGS 65

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
             GVG P ++GVSGA +LR   EL+   G+ +GNA+ Q++G  PK+G RR EA+AVLS +
Sbjct: 66  FVGVGRPEYDGVSGAKLLRECRELLESEGFIIGNAAAQLIGQTPKMGPRREEAEAVLSEI 125

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           L APVSVS                  +ATA+V
Sbjct: 126 LGAPVSVSATTTDHMGFTGRKEGRAAVATAVV 157


>sp|B1VIQ0|ISPF_CORU7 Tax_Id=504474 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Corynebacterium urealyticum]
          Length = 162

 Score =  157 bits (398), Expect = 3e-37
 Identities = 72/152 (47%), Positives = 101/152 (66%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRVG+  D H +EPG+PCW+ GLLF  ADGC GHSDGDV +H + DA+LSA+GLGD+G 
Sbjct: 6   IPRVGIASDAHQVEPGKPCWMAGLLFEDADGCEGHSDGDVVSHVIVDALLSASGLGDLGS 65

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
             GVG   ++GVSG  ++    +L+ ++G+ +GN + Q++GNRPK+G RR EA+  L+ L
Sbjct: 66  FVGVGRKEYDGVSGERLITECRQLLAENGFTIGNVAAQMIGNRPKMGPRREEAERRLTEL 125

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           + APVSVS                  +ATA+V
Sbjct: 126 VGAPVSVSATTTDKMGFTGRGEGVAALATAVV 157


>tr|C2BMC6|C2BMC6_9CORY Tax_Id=525264 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Corynebacterium pseudogenitalium
           ATCC 33035]
          Length = 160

 Score =  157 bits (398), Expect = 3e-37
 Identities = 78/152 (51%), Positives = 99/152 (65%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRVG+  D H IE G+ CW+ GLLF    GC GHSDGDV AHAL DA+LSA+ LGD+G 
Sbjct: 6   VPRVGIATDAHQIEAGKECWIAGLLFEGDAGCEGHSDGDVVAHALVDALLSASHLGDLGS 65

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
             GVG P ++GVSGA +LR   EL+   G+ +GNA+ Q++G  PK+G RR EA+AVLS +
Sbjct: 66  FVGVGRPEYDGVSGAKLLRECRELLESEGFIIGNAAAQLIGQTPKMGPRRAEAEAVLSEI 125

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           L APVSVS                  +ATA+V
Sbjct: 126 LGAPVSVSATTTDHMGFTGRKEGRAAVATAVV 157


>tr|B5GP17|B5GP17_STRCL Tax_Id=443255 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Streptomyces clavuligerus ATCC
           27064]
          Length = 173

 Score =  157 bits (397), Expect = 4e-37
 Identities = 78/153 (50%), Positives = 94/153 (61%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LP +G+G DVH  E GR  W  GL +P  DG AGHSDGDVAAHA CDA+ SAAG+GD+G 
Sbjct: 17  LPLIGIGTDVHAFEAGRELWCAGLHWPGEDGLAGHSDGDVAAHAACDALFSAAGVGDLGA 76

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
            FG   P W G SG T+L     ++   G+ +GN ++QV+G RPKIG RR EAQ VLS  
Sbjct: 77  HFGTSRPEWSGASGITLLAEAARIVRAEGFAIGNVAIQVIGVRPKIGKRRDEAQKVLSEA 136

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           + APVSVS                  IATAL+V
Sbjct: 137 VGAPVSVSGTTTDGLGLTGRAEGLAAIATALLV 169


>sp|Q4JXJ6|ISPF_CORJK Tax_Id=306537 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Corynebacterium jeikeium]
          Length = 163

 Score =  156 bits (394), Expect = 8e-37
 Identities = 75/152 (49%), Positives = 99/152 (65%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           +PRVG+  D H ++PG+ CW+  LL+   DGC GHSDGDV AHA+ DA+LSAAGLGD+G 
Sbjct: 7   IPRVGIATDAHQVQPGKDCWMACLLWEDQDGCEGHSDGDVVAHAVVDALLSAAGLGDLGS 66

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
             GVG   ++ VSG  +LR   EL+   G+ +GNA+VQ+VGNRPK+G RR EA+ V+  L
Sbjct: 67  FVGVGRQEYDNVSGERLLRECRELLESKGFVIGNAAVQMVGNRPKMGTRREEAEKVMGEL 126

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALV 155
           + APVSVS                  +ATA+V
Sbjct: 127 IGAPVSVSATTTDHMGFTGRGEGVAAVATAVV 158


>sp|Q0RBN8|ISPF_FRAAA Tax_Id=326424 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Frankia alni]
          Length = 160

 Score =  155 bits (392), Expect = 1e-36
 Identities = 79/153 (51%), Positives = 97/153 (63%)

Query: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63
           LPRVG+GVDVHP   GRPCW+  L +P   G AGHSDGDVAAHA CDA+L+A+ LGD+G 
Sbjct: 6   LPRVGIGVDVHPFAAGRPCWVACLEWPGETGLAGHSDGDVAAHATCDALLTASCLGDLGK 65

Query: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123
           VFG   P + G SGA +L     L+   G+ +GN SVQV+GNRP++  RR +AQA +S  
Sbjct: 66  VFGTDRPEYAGASGAVLLAETARLLAVGGWVIGNVSVQVIGNRPRMAARREQAQAAMSAA 125

Query: 124 LNAPVSVSXXXXXXXXXXXXXXXXXXIATALVV 156
           L A VS+S                  IATALVV
Sbjct: 126 LGASVSLSATTTDGLGLTGRGEGLAAIATALVV 158


  Database: Amellifera_nr
    Posted date:  Feb 5, 2010  5:10 AM
  Number of letters in database: 3,846,993,858
  Number of sequences in database:  11,275,203
  
Lambda     K      H
   0.320    0.140    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11275203
Number of Hits to DB: 1,160,167,169
Number of extensions: 44607855
Number of successful extensions: 93727
Number of sequences better than 10.0: 1528
Number of HSP's gapped: 94396
Number of HSP's successfully gapped: 1528
Length of query: 165
Length of database: 3,846,993,858
Length adjustment: 126
Effective length of query: 39
Effective length of database: 2,426,318,280
Effective search space: 94626412920
Effective search space used: 94626412920
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 75 (33.5 bits)