BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_5215 (429 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HKC3|B2HKC3_MYCMM Tax_Id=216594 (gshA)SubName: Full=Glutama... 766 0.0 tr|Q744N5|Q744N5_MYCPA Tax_Id=1770 (gshA)SubName: Full=GshA;[Myc... 572 e-161 tr|A0Q9U6|A0Q9U6_MYCA1 Tax_Id=243243 SubName: Full=Putative glut... 571 e-161 tr|Q7TVW1|Q7TVW1_MYCBO Tax_Id=1765 (gshA)SubName: Full=GLUTAMATE... 558 e-157 tr|O69672|O69672_MYCTU Tax_Id=1773 (gshA)SubName: Full=GLUTAMATE... 558 e-157 tr|C6DNE3|C6DNE3_MYCTK Tax_Id=478434 SubName: Full=Glutamate-cys... 558 e-157 tr|C1AIF7|C1AIF7_MYCBT Tax_Id=561275 (gshA)SubName: Full=Glutama... 558 e-157 tr|A5U929|A5U929_MYCTA Tax_Id=419947 (gshA)SubName: Full=Putativ... 558 e-157 tr|A1KQ35|A1KQ35_MYCBP Tax_Id=410289 (gshA)SubName: Full=Glutama... 558 e-157 tr|A4KMH1|A4KMH1_MYCTU Tax_Id=395095 SubName: Full=Glutamate-cys... 558 e-157 tr|A2VM86|A2VM86_MYCTU Tax_Id=348776 SubName: Full=Glutamate-cys... 558 e-157 tr|A5WTS1|A5WTS1_MYCTF Tax_Id=336982 SubName: Full=Glutamate-cys... 557 e-156 tr|Q1B298|Q1B298_MYCSS Tax_Id=164756 SubName: Full=Glutamate--cy... 518 e-145 tr|A3Q786|A3Q786_MYCSJ Tax_Id=164757 SubName: Full=Glutamate--cy... 518 e-145 tr|A1UMV2|A1UMV2_MYCSK Tax_Id=189918 SubName: Full=Glutamate--cy... 518 e-145 tr|A1TGF5|A1TGF5_MYCVP Tax_Id=350058 SubName: Full=Glutamate--cy... 514 e-144 tr|A0R5N1|A0R5N1_MYCS2 Tax_Id=246196 SubName: Full=Glutamate--cy... 511 e-143 tr|A4T5Z6|A4T5Z6_MYCGI Tax_Id=350054 SubName: Full=Glutamate--cy... 506 e-141 tr|C0U1D6|C0U1D6_9ACTO Tax_Id=526225 SubName: Full=Glutamate--cy... 369 e-100 tr|B1MFR8|B1MFR8_MYCA9 Tax_Id=561007 SubName: Full=Glutamate--cy... 364 1e-98 tr|D1ACB6|D1ACB6_THECU Tax_Id=471852 SubName: Full=Glutamate/cys... 246 4e-63 tr|Q0RAS7|Q0RAS7_FRAAA Tax_Id=326424 (gshA)SubName: Full=Glutama... 235 9e-60 tr|Q2J4D5|Q2J4D5_FRASC Tax_Id=106370 SubName: Full=Glutamate--cy... 232 8e-59 tr|A8L8S2|A8L8S2_FRASN Tax_Id=298653 SubName: Full=Glutamate--cy... 229 5e-58 tr|C1YNM4|C1YNM4_NOCDA Tax_Id=446468 SubName: Full=Glutamate--cy... 224 1e-56 tr|C8XBM8|C8XBM8_NAKMY Tax_Id=479431 SubName: Full=Glutamate/cys... 223 4e-56 tr|C6WGZ9|C6WGZ9_ACTMD Tax_Id=446462 SubName: Full=Glutamate--cy... 216 5e-54 tr|B5I149|B5I149_9ACTO Tax_Id=463191 SubName: Full=Putative unch... 213 3e-53 tr|C4E2X6|C4E2X6_STRRS Tax_Id=479432 SubName: Full=Glutamate--cy... 209 4e-52 tr|A0ADU7|A0ADU7_STRAM Tax_Id=278992 SubName: Full=Putative glut... 208 9e-52 tr|C9NJF2|C9NJF2_9ACTO Tax_Id=591167 SubName: Full=Glutamate/cys... 205 1e-50 tr|Q8GPN7|Q8GPN7_STRAW Tax_Id=33903 SubName: Full=Putative uncha... 199 7e-49 tr|Q825V6|Q825V6_STRAW Tax_Id=33903 (gshA)SubName: Full=Putative... 197 2e-48 tr|B1VRV6|B1VRV6_STRGG Tax_Id=455632 SubName: Full=Putative glut... 196 6e-48 tr|B4V5Z6|B4V5Z6_9ACTO Tax_Id=465541 SubName: Full=Glutamate-cys... 195 8e-48 tr|C1WR11|C1WR11_9ACTO Tax_Id=479435 SubName: Full=Gamma-glutamy... 194 1e-47 tr|Q9RD01|Q9RD01_STRCO Tax_Id=1902 SubName: Full=Putative unchar... 190 3e-46 tr|C9Z4Y5|C9Z4Y5_STRSW Tax_Id=680198 SubName: Full=Putative unch... 190 3e-46 tr|C7MXH6|C7MXH6_SACVD Tax_Id=471857 SubName: Full=Gamma-glutamy... 187 2e-45 tr|C1AY21|C1AY21_RHOOB Tax_Id=632772 (gshA)SubName: Full=Putativ... 170 4e-40 tr|A4FGC2|A4FGC2_SACEN Tax_Id=405948 (gshA)SubName: Full=Glutama... 170 4e-40 tr|Q0S4Q7|Q0S4Q7_RHOSR Tax_Id=101510 SubName: Full=Probable glut... 166 4e-39 tr|A4X6R4|A4X6R4_SALTO Tax_Id=369723 SubName: Full=Glutamate--cy... 165 9e-39 tr|C7QH01|C7QH01_CATAD Tax_Id=479433 SubName: Full=Glutamate--cy... 159 5e-37 tr|Q5YQ02|Q5YQ02_NOCFA Tax_Id=37329 (gshA)SubName: Full=Putative... 158 1e-36 tr|A8M1F4|A8M1F4_SALAI Tax_Id=391037 SubName: Full=Glutamate--cy... 158 1e-36 tr|C3JX20|C3JX20_RHOER Tax_Id=596309 SubName: Full=Glutamate--cy... 158 1e-36 tr|C1A343|C1A343_RHOE4 Tax_Id=234621 (gshA)SubName: Full=Putativ... 157 3e-36 tr|C4RDQ5|C4RDQ5_9ACTO Tax_Id=219305 SubName: Full=Glutamate-cys... 149 5e-34 tr|C4DSG7|C4DSG7_9ACTO Tax_Id=446470 SubName: Full=Gamma-glutamy... 140 3e-31 >tr|B2HKC3|B2HKC3_MYCMM Tax_Id=216594 (gshA)SubName: Full=Glutamate--cysteine ligase GshA;[Mycobacterium marinum] Length = 429 Score = 766 bits (1977), Expect = 0.0 Identities = 379/429 (88%), Positives = 379/429 (88%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MTFAPSPAATSQL QYIANGCLVDGPIGRVGLEIEAHCYDPADP Sbjct: 1 MTFAPSPAATSQLDSSRAADADIAGSAVAAQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA Sbjct: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFF IQVNLDA Sbjct: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFTASQSGMAGAAMMTSTASIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS Sbjct: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAVAVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTT 300 ADDPATDWAHYALKAPVMLVHNPDAVAVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTT Sbjct: 241 ADDPATDWAHYALKAPVMLVHNPDAVAVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTT 300 Query: 301 LFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAAR 360 LFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAAR Sbjct: 301 LFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAAR 360 Query: 361 AGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGVAPA 420 AGLGDPRLHAAASRCV QSLLAYVQRGRCPGDDFGDQVTEHGVAPA Sbjct: 361 AGLGDPRLHAAASRCVAIAAERAPAELADALQSLLAYVQRGRCPGDDFGDQVTEHGVAPA 420 Query: 421 IARLARGEQ 429 IARLARGEQ Sbjct: 421 IARLARGEQ 429 >tr|Q744N5|Q744N5_MYCPA Tax_Id=1770 (gshA)SubName: Full=GshA;[Mycobacterium paratuberculosis] Length = 436 Score = 572 bits (1473), Expect = e-161 Identities = 286/433 (66%), Positives = 319/433 (73%), Gaps = 4/433 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXX----QYIANGCLVDGPIGRVGLEIEAHCYD 56 MTFAPS AA S+ QYIA GCL D P+GRVGLE+EAHC+D Sbjct: 1 MTFAPSTAAASRPAGGDPAAELRIAELTDSAAVAQYIARGCLADAPLGRVGLEVEAHCHD 60 Query: 57 PADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAV 116 P DP RRP W+EI VL+ L PGGS VTVEPGGAVELSGPP DG+LAAIDAM RDQAV Sbjct: 61 PQDPCRRPGWDEIAAVLDALPALPGGSRVTVEPGGAVELSGPPADGVLAAIDAMRRDQAV 120 Query: 117 LRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQV 176 LR AFA AGLGLV LGADP+RP RINPGARY+AME+FF IQV Sbjct: 121 LRPAFAGAGLGLVFLGADPLRPPQRINPGARYRAMERFFATSRSGEAGAAMMTSTASIQV 180 Query: 177 NLDAGPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPI 236 N+DAGP+ GWA+RVRLAHALGPTMIA+ ANSPML G+F+GW S+RQRVWG+MD RCGP+ Sbjct: 181 NVDAGPREGWAARVRLAHALGPTMIAMTANSPMLDGDFTGWVSSRQRVWGRMDSARCGPV 240 Query: 237 LGASADDPATDWAHYALKAPVMLVHNPDAVAVTHHVPFADWVDGRVLLGDRRPTYADLDY 296 LGAS DDP TDWA YALKAPVMLVH PDA AVT VPFADWVDGRVLLG RRPT ADL+Y Sbjct: 241 LGASGDDPGTDWARYALKAPVMLVHTPDAEAVTRWVPFADWVDGRVLLGGRRPTVADLEY 300 Query: 297 HLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWD 356 HLTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLV LLDDP AA LA AV+PVAT WD Sbjct: 301 HLTTLFPPVRPRQWLEIRYLDSVPDTLWPAVVFTLVALLDDPVAAGLAARAVEPVATAWD 360 Query: 357 TAARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHG 416 AAR GL D RL+AAA+ C+ + L+ V++GRCPGDDF DQV EHG Sbjct: 361 VAARVGLRDRRLYAAANACLAIAAERAPAELAEPMRRLVRLVEQGRCPGDDFADQVIEHG 420 Query: 417 VAPAIARLARGEQ 429 +A +++R ARG Q Sbjct: 421 IAASVSRAARGPQ 433 >tr|A0Q9U6|A0Q9U6_MYCA1 Tax_Id=243243 SubName: Full=Putative glutamate--cysteine ligase; EC=6.3.2.2;[Mycobacterium avium] Length = 436 Score = 571 bits (1472), Expect = e-161 Identities = 286/433 (66%), Positives = 319/433 (73%), Gaps = 4/433 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXX----QYIANGCLVDGPIGRVGLEIEAHCYD 56 MTFAPS AA S+ YIA GCL D P+GRVGLE+EAHC+D Sbjct: 1 MTFAPSTAAASRPAGGDPAAELRIAELTDSAAVAHYIARGCLADAPLGRVGLEVEAHCHD 60 Query: 57 PADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAV 116 P DP RRP W+EI VL+ L PGGS VTVEPGGAVELSGPP DG+LAAIDAM RDQAV Sbjct: 61 PQDPCRRPGWDEIAAVLDALPALPGGSRVTVEPGGAVELSGPPADGVLAAIDAMRRDQAV 120 Query: 117 LRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQV 176 LR AFA+AGLGLV LGADP+RP RINPGARY+AME+FF IQV Sbjct: 121 LRPAFAEAGLGLVFLGADPLRPPQRINPGARYRAMERFFATSRSGEAGAAMMTSTASIQV 180 Query: 177 NLDAGPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPI 236 N+DAGP+ GWA+RVRLAHALGPTMIA+ ANSPML G+F+GW S+RQRVWG+MD RCGPI Sbjct: 181 NVDAGPREGWAARVRLAHALGPTMIAMTANSPMLDGDFTGWVSSRQRVWGRMDSARCGPI 240 Query: 237 LGASADDPATDWAHYALKAPVMLVHNPDAVAVTHHVPFADWVDGRVLLGDRRPTYADLDY 296 LGAS DDP TDWA YALKAPVMLVH PDA AVT VPFADWVDGRVLLG RRPT ADL+Y Sbjct: 241 LGASGDDPGTDWARYALKAPVMLVHTPDAEAVTRWVPFADWVDGRVLLGGRRPTVADLEY 300 Query: 297 HLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWD 356 HLTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLV LLDDP AA LA AV+PVAT WD Sbjct: 301 HLTTLFPPVRPRQWLEIRYLDSVPDTLWPAVVFTLVALLDDPVAAGLAARAVEPVATAWD 360 Query: 357 TAARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHG 416 AAR GL D RL+AAA+ C+ + L+ V++GRCPGDDF DQV EHG Sbjct: 361 VAARVGLRDRRLYAAANACLAIAAERAPAELAEPMRRLVRLVEQGRCPGDDFADQVIEHG 420 Query: 417 VAPAIARLARGEQ 429 +A +++R ARG Q Sbjct: 421 IAASVSRAARGPQ 433 >tr|Q7TVW1|Q7TVW1_MYCBO Tax_Id=1765 (gshA)SubName: Full=GLUTAMATE--CYSTEINE LIGASE GSHA (GAMMA-GLUTAMYLCYSTEINE SYNTHETASE) (GAMMA-ECS) (GCS) (GAMMA-GLUTAMYL-L-CYSTEINE SYNTHETASE); EC=6.3.2.2;[Mycobacterium bovis] Length = 432 Score = 558 bits (1437), Expect = e-157 Identities = 284/430 (66%), Positives = 314/430 (73%), Gaps = 3/430 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MT A AA SQL +YIA+GCLVDGP+GRVGLE+EAHC+DPADP Sbjct: 1 MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 RRPSWEEI +VLE L PGGS V+VEPGGAVELSGPP DG+LAAI AM RDQAVLRSA Sbjct: 61 FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 A+AGLGLV LGADP+R +R+NPGARY+AMEQFF IQVNLDA Sbjct: 121 LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQ GWA RVRLAHALGPTMIAIAANSPMLGG FSGW+STRQRVWGQMD RCGPILGAS Sbjct: 181 GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAV---AVTHHVPFADWVDGRVLLGDRRPTYADLDYH 297 D P DWA YALKAPVM+V +PD AVT +VPF DWVDGRVLL RR T ADL YH Sbjct: 241 GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH 300 Query: 298 LTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDT 357 LTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLVTLLDDP AA+LA +AV+PVAT WDT Sbjct: 301 LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT 360 Query: 358 AARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGV 417 AAR GL D RL+ AA+RC+ Q L+ +V RG CP DDF D+V G+ Sbjct: 361 AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI 420 Query: 418 APAIARLARG 427 A A+ + G Sbjct: 421 ASAVTGMMHG 430 >tr|O69672|O69672_MYCTU Tax_Id=1773 (gshA)SubName: Full=GLUTAMATE--CYSTEINE LIGASE GSHA (GAMMA-GLUTAMYLCYSTEINE SYNTHETASE) (GAMMA-ECS) (GCS) (GAMMA-GLUTAMYL-L-CYSTEINE SYNTHETASE); EC=6.3.2.2; SubName: Full=Glutamate--cysteine ligase, putative;[Mycobacterium tuberculosis] Length = 432 Score = 558 bits (1437), Expect = e-157 Identities = 284/430 (66%), Positives = 314/430 (73%), Gaps = 3/430 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MT A AA SQL +YIA+GCLVDGP+GRVGLE+EAHC+DPADP Sbjct: 1 MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 RRPSWEEI +VLE L PGGS V+VEPGGAVELSGPP DG+LAAI AM RDQAVLRSA Sbjct: 61 FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 A+AGLGLV LGADP+R +R+NPGARY+AMEQFF IQVNLDA Sbjct: 121 LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQ GWA RVRLAHALGPTMIAIAANSPMLGG FSGW+STRQRVWGQMD RCGPILGAS Sbjct: 181 GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAV---AVTHHVPFADWVDGRVLLGDRRPTYADLDYH 297 D P DWA YALKAPVM+V +PD AVT +VPF DWVDGRVLL RR T ADL YH Sbjct: 241 GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH 300 Query: 298 LTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDT 357 LTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLVTLLDDP AA+LA +AV+PVAT WDT Sbjct: 301 LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT 360 Query: 358 AARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGV 417 AAR GL D RL+ AA+RC+ Q L+ +V RG CP DDF D+V G+ Sbjct: 361 AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI 420 Query: 418 APAIARLARG 427 A A+ + G Sbjct: 421 ASAVTGMMHG 430 >tr|C6DNE3|C6DNE3_MYCTK Tax_Id=478434 SubName: Full=Glutamate-cysteine ligase gshA;[Mycobacterium tuberculosis] Length = 432 Score = 558 bits (1437), Expect = e-157 Identities = 284/430 (66%), Positives = 314/430 (73%), Gaps = 3/430 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MT A AA SQL +YIA+GCLVDGP+GRVGLE+EAHC+DPADP Sbjct: 1 MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 RRPSWEEI +VLE L PGGS V+VEPGGAVELSGPP DG+LAAI AM RDQAVLRSA Sbjct: 61 FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 A+AGLGLV LGADP+R +R+NPGARY+AMEQFF IQVNLDA Sbjct: 121 LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQ GWA RVRLAHALGPTMIAIAANSPMLGG FSGW+STRQRVWGQMD RCGPILGAS Sbjct: 181 GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAV---AVTHHVPFADWVDGRVLLGDRRPTYADLDYH 297 D P DWA YALKAPVM+V +PD AVT +VPF DWVDGRVLL RR T ADL YH Sbjct: 241 GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH 300 Query: 298 LTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDT 357 LTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLVTLLDDP AA+LA +AV+PVAT WDT Sbjct: 301 LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT 360 Query: 358 AARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGV 417 AAR GL D RL+ AA+RC+ Q L+ +V RG CP DDF D+V G+ Sbjct: 361 AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI 420 Query: 418 APAIARLARG 427 A A+ + G Sbjct: 421 ASAVTGMMHG 430 >tr|C1AIF7|C1AIF7_MYCBT Tax_Id=561275 (gshA)SubName: Full=Glutamate--cysteine ligase GshA; EC=6.3.2.2;[Mycobacterium bovis] Length = 432 Score = 558 bits (1437), Expect = e-157 Identities = 284/430 (66%), Positives = 314/430 (73%), Gaps = 3/430 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MT A AA SQL +YIA+GCLVDGP+GRVGLE+EAHC+DPADP Sbjct: 1 MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 RRPSWEEI +VLE L PGGS V+VEPGGAVELSGPP DG+LAAI AM RDQAVLRSA Sbjct: 61 FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 A+AGLGLV LGADP+R +R+NPGARY+AMEQFF IQVNLDA Sbjct: 121 LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQ GWA RVRLAHALGPTMIAIAANSPMLGG FSGW+STRQRVWGQMD RCGPILGAS Sbjct: 181 GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAV---AVTHHVPFADWVDGRVLLGDRRPTYADLDYH 297 D P DWA YALKAPVM+V +PD AVT +VPF DWVDGRVLL RR T ADL YH Sbjct: 241 GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH 300 Query: 298 LTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDT 357 LTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLVTLLDDP AA+LA +AV+PVAT WDT Sbjct: 301 LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT 360 Query: 358 AARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGV 417 AAR GL D RL+ AA+RC+ Q L+ +V RG CP DDF D+V G+ Sbjct: 361 AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI 420 Query: 418 APAIARLARG 427 A A+ + G Sbjct: 421 ASAVTGMMHG 430 >tr|A5U929|A5U929_MYCTA Tax_Id=419947 (gshA)SubName: Full=Putative glutamate--cysteine ligase;[Mycobacterium tuberculosis] Length = 432 Score = 558 bits (1437), Expect = e-157 Identities = 284/430 (66%), Positives = 314/430 (73%), Gaps = 3/430 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MT A AA SQL +YIA+GCLVDGP+GRVGLE+EAHC+DPADP Sbjct: 1 MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 RRPSWEEI +VLE L PGGS V+VEPGGAVELSGPP DG+LAAI AM RDQAVLRSA Sbjct: 61 FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 A+AGLGLV LGADP+R +R+NPGARY+AMEQFF IQVNLDA Sbjct: 121 LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQ GWA RVRLAHALGPTMIAIAANSPMLGG FSGW+STRQRVWGQMD RCGPILGAS Sbjct: 181 GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAV---AVTHHVPFADWVDGRVLLGDRRPTYADLDYH 297 D P DWA YALKAPVM+V +PD AVT +VPF DWVDGRVLL RR T ADL YH Sbjct: 241 GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH 300 Query: 298 LTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDT 357 LTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLVTLLDDP AA+LA +AV+PVAT WDT Sbjct: 301 LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT 360 Query: 358 AARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGV 417 AAR GL D RL+ AA+RC+ Q L+ +V RG CP DDF D+V G+ Sbjct: 361 AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI 420 Query: 418 APAIARLARG 427 A A+ + G Sbjct: 421 ASAVTGMMHG 430 >tr|A1KQ35|A1KQ35_MYCBP Tax_Id=410289 (gshA)SubName: Full=Glutamate--cysteine ligase gshA (GAMMA-GLUTAMYLCYSTEINE SYNTHETASE) (GAMMA-ECS) (GCS) (GAMMA-GLUTAMYL-L-CYSTEINE SYNTHETASE); EC=6.3.2.2;[Mycobacterium bovis] Length = 432 Score = 558 bits (1437), Expect = e-157 Identities = 284/430 (66%), Positives = 314/430 (73%), Gaps = 3/430 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MT A AA SQL +YIA+GCLVDGP+GRVGLE+EAHC+DPADP Sbjct: 1 MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 RRPSWEEI +VLE L PGGS V+VEPGGAVELSGPP DG+LAAI AM RDQAVLRSA Sbjct: 61 FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 A+AGLGLV LGADP+R +R+NPGARY+AMEQFF IQVNLDA Sbjct: 121 LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQ GWA RVRLAHALGPTMIAIAANSPMLGG FSGW+STRQRVWGQMD RCGPILGAS Sbjct: 181 GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAV---AVTHHVPFADWVDGRVLLGDRRPTYADLDYH 297 D P DWA YALKAPVM+V +PD AVT +VPF DWVDGRVLL RR T ADL YH Sbjct: 241 GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH 300 Query: 298 LTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDT 357 LTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLVTLLDDP AA+LA +AV+PVAT WDT Sbjct: 301 LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT 360 Query: 358 AARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGV 417 AAR GL D RL+ AA+RC+ Q L+ +V RG CP DDF D+V G+ Sbjct: 361 AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI 420 Query: 418 APAIARLARG 427 A A+ + G Sbjct: 421 ASAVTGMMHG 430 >tr|A4KMH1|A4KMH1_MYCTU Tax_Id=395095 SubName: Full=Glutamate-cysteine ligase gshA;[Mycobacterium tuberculosis str. Haarlem] Length = 432 Score = 558 bits (1437), Expect = e-157 Identities = 284/430 (66%), Positives = 314/430 (73%), Gaps = 3/430 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MT A AA SQL +YIA+GCLVDGP+GRVGLE+EAHC+DPADP Sbjct: 1 MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 RRPSWEEI +VLE L PGGS V+VEPGGAVELSGPP DG+LAAI AM RDQAVLRSA Sbjct: 61 FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 A+AGLGLV LGADP+R +R+NPGARY+AMEQFF IQVNLDA Sbjct: 121 LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQ GWA RVRLAHALGPTMIAIAANSPMLGG FSGW+STRQRVWGQMD RCGPILGAS Sbjct: 181 GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAV---AVTHHVPFADWVDGRVLLGDRRPTYADLDYH 297 D P DWA YALKAPVM+V +PD AVT +VPF DWVDGRVLL RR T ADL YH Sbjct: 241 GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH 300 Query: 298 LTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDT 357 LTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLVTLLDDP AA+LA +AV+PVAT WDT Sbjct: 301 LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT 360 Query: 358 AARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGV 417 AAR GL D RL+ AA+RC+ Q L+ +V RG CP DDF D+V G+ Sbjct: 361 AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI 420 Query: 418 APAIARLARG 427 A A+ + G Sbjct: 421 ASAVTGMMHG 430 >tr|A2VM86|A2VM86_MYCTU Tax_Id=348776 SubName: Full=Glutamate-cysteine ligase gshA;[Mycobacterium tuberculosis C] Length = 432 Score = 558 bits (1437), Expect = e-157 Identities = 284/430 (66%), Positives = 314/430 (73%), Gaps = 3/430 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MT A AA SQL +YIA+GCLVDGP+GRVGLE+EAHC+DPADP Sbjct: 1 MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 RRPSWEEI +VLE L PGGS V+VEPGGAVELSGPP DG+LAAI AM RDQAVLRSA Sbjct: 61 FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 A+AGLGLV LGADP+R +R+NPGARY+AMEQFF IQVNLDA Sbjct: 121 LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQ GWA RVRLAHALGPTMIAIAANSPMLGG FSGW+STRQRVWGQMD RCGPILGAS Sbjct: 181 GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAV---AVTHHVPFADWVDGRVLLGDRRPTYADLDYH 297 D P DWA YALKAPVM+V +PD AVT +VPF DWVDGRVLL RR T ADL YH Sbjct: 241 GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH 300 Query: 298 LTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDT 357 LTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLVTLLDDP AA+LA +AV+PVAT WDT Sbjct: 301 LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT 360 Query: 358 AARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGV 417 AAR GL D RL+ AA+RC+ Q L+ +V RG CP DDF D+V G+ Sbjct: 361 AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI 420 Query: 418 APAIARLARG 427 A A+ + G Sbjct: 421 ASAVTGMMHG 430 >tr|A5WTS1|A5WTS1_MYCTF Tax_Id=336982 SubName: Full=Glutamate-cysteine ligase gshA;[Mycobacterium tuberculosis] Length = 432 Score = 557 bits (1435), Expect = e-156 Identities = 284/430 (66%), Positives = 314/430 (73%), Gaps = 3/430 (0%) Query: 1 MTFAPSPAATSQLXXXXXXXXXXXXXXXXXQYIANGCLVDGPIGRVGLEIEAHCYDPADP 60 MT A AA SQL +YIA+GCLVDGP+GRVGLE+EAHC+DPADP Sbjct: 1 MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP 60 Query: 61 HRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSA 120 RRPSWEEI +VLE L PGGS V+VEPGGAVELSGPP DG+LAAI AM RDQAVLRSA Sbjct: 61 FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA 120 Query: 121 FADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDA 180 A+AGLGLV LGADP+R +R+NPGARY+AMEQFF IQVNLDA Sbjct: 121 LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA 180 Query: 181 GPQSGWASRVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS 240 GPQ GWA RVRLAHALGPTMIAIAANSPMLGG FSGW+STRQRVWGQMD RCGPILGAS Sbjct: 181 GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSTRCGPILGAS 240 Query: 241 ADDPATDWAHYALKAPVMLVHNPDAV---AVTHHVPFADWVDGRVLLGDRRPTYADLDYH 297 D P DWA YALKAPVM+V +PD AVT +VPF DWVDGRVLL RR T ADL YH Sbjct: 241 GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH 300 Query: 298 LTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDT 357 LTTLFPPVRPRQWLEIRYLDS+ D WPAVVFTLVTLLDDP AA+LA +AV+PVAT WDT Sbjct: 301 LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT 360 Query: 358 AARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGV 417 AAR GL D RL+ AA+RC+ Q L+ +V RG CP DDF D+V G+ Sbjct: 361 AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI 420 Query: 418 APAIARLARG 427 A A+ + G Sbjct: 421 ASAVTGMMHG 430 >tr|Q1B298|Q1B298_MYCSS Tax_Id=164756 SubName: Full=Glutamate--cysteine ligase, GCS2;[Mycobacterium sp.] Length = 424 Score = 518 bits (1334), Expect = e-145 Identities = 247/398 (62%), Positives = 293/398 (73%) Query: 31 QYIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPG 90 ++I CL DGP+G+VGLE+EAH +D ADP RRP W E+ D + G+G PGGS +TVEPG Sbjct: 26 EHITEHCLHDGPVGQVGLEVEAHSFDLADPRRRPDWGEVTDAIAGVGALPGGSRITVEPG 85 Query: 91 GAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQA 150 GAVELSGPP DG +AAI AM D+AVLR+AFA GLGLV +GADP+R R+NPG RY A Sbjct: 86 GAVELSGPPADGSVAAIAAMTSDRAVLRTAFAQRGLGLVLVGADPLRRPRRVNPGGRYSA 145 Query: 151 MEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMIAIAANSPML 210 ME FF IQ+NLDAGP+ GWA RVRLAHALGPTMIA ANSP+L Sbjct: 146 MEAFFTASGTGAAGAFMMTSTASIQLNLDAGPRRGWADRVRLAHALGPTMIAATANSPLL 205 Query: 211 GGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNPDAVAVTH 270 G FSGW+S+RQ VWG++D+ RCGP+LGAS DDPA+DWA YAL+APVMLVHNP+ V VT Sbjct: 206 AGRFSGWQSSRQWVWGELDEARCGPVLGASGDDPASDWARYALRAPVMLVHNPEPVPVTD 265 Query: 271 HVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFT 330 VPFA+W DG+ LLG RRPT +DL+YHLTTLFPPVRPR+WLEIRYLD++SD WPAV FT Sbjct: 266 WVPFAEWADGQTLLGGRRPTRSDLEYHLTTLFPPVRPRRWLEIRYLDAVSDALWPAVAFT 325 Query: 331 LVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXXXX 390 L TLLDDP AA++A EA + VAT WD AAR GLGD RLHAAA RCV Sbjct: 326 LTTLLDDPAAADIAAEATESVATAWDRAARIGLGDRRLHAAALRCVETAAERAPAAVMES 385 Query: 391 XQSLLAYVQRGRCPGDDFGDQVTEHGVAPAIARLARGE 428 Q L+ V+ GR P DDF D+ +G+ PA+ +LA+GE Sbjct: 386 MQQLVRSVEEGRSPADDFADRAVAYGIGPAVRQLAKGE 423 >tr|A3Q786|A3Q786_MYCSJ Tax_Id=164757 SubName: Full=Glutamate--cysteine ligase, GCS2;[Mycobacterium sp.] Length = 424 Score = 518 bits (1334), Expect = e-145 Identities = 247/398 (62%), Positives = 293/398 (73%) Query: 31 QYIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPG 90 ++I CL DGP+G+VGLE+EAH +D ADP RRP W E+ D + G+G PGGS +TVEPG Sbjct: 26 EHITEHCLHDGPVGQVGLEVEAHSFDLADPRRRPDWGEVTDAIAGVGALPGGSRITVEPG 85 Query: 91 GAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQA 150 GAVELSGPP DG +AAI AM D+AVLR+AFA GLGLV +GADP+R R+NPG RY A Sbjct: 86 GAVELSGPPADGSVAAIAAMTSDRAVLRTAFAQRGLGLVLVGADPLRRPRRVNPGGRYSA 145 Query: 151 MEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMIAIAANSPML 210 ME FF IQ+NLDAGP+ GWA RVRLAHALGPTMIA ANSP+L Sbjct: 146 MEAFFTASGTGAAGAFMMTSTASIQLNLDAGPRRGWADRVRLAHALGPTMIAATANSPLL 205 Query: 211 GGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNPDAVAVTH 270 G FSGW+S+RQ VWG++D+ RCGP+LGAS DDPA+DWA YAL+APVMLVHNP+ V VT Sbjct: 206 AGRFSGWQSSRQWVWGELDEARCGPVLGASGDDPASDWARYALRAPVMLVHNPEPVPVTD 265 Query: 271 HVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFT 330 VPFA+W DG+ LLG RRPT +DL+YHLTTLFPPVRPR+WLEIRYLD++SD WPAV FT Sbjct: 266 WVPFAEWADGQTLLGGRRPTRSDLEYHLTTLFPPVRPRRWLEIRYLDAVSDALWPAVAFT 325 Query: 331 LVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXXXX 390 L TLLDDP AA++A EA + VAT WD AAR GLGD RLHAAA RCV Sbjct: 326 LTTLLDDPAAADIAAEATESVATAWDRAARIGLGDRRLHAAALRCVETAAERAPAAVMES 385 Query: 391 XQSLLAYVQRGRCPGDDFGDQVTEHGVAPAIARLARGE 428 Q L+ V+ GR P DDF D+ +G+ PA+ +LA+GE Sbjct: 386 MQQLVRSVEEGRSPADDFADRAVAYGIGPAVRQLAKGE 423 >tr|A1UMV2|A1UMV2_MYCSK Tax_Id=189918 SubName: Full=Glutamate--cysteine ligase, GCS2;[Mycobacterium sp.] Length = 424 Score = 518 bits (1334), Expect = e-145 Identities = 247/398 (62%), Positives = 293/398 (73%) Query: 31 QYIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPG 90 ++I CL DGP+G+VGLE+EAH +D ADP RRP W E+ D + G+G PGGS +TVEPG Sbjct: 26 EHITEHCLHDGPVGQVGLEVEAHSFDLADPRRRPDWGEVTDAIAGVGALPGGSRITVEPG 85 Query: 91 GAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQA 150 GAVELSGPP DG +AAI AM D+AVLR+AFA GLGLV +GADP+R R+NPG RY A Sbjct: 86 GAVELSGPPADGSVAAIAAMTSDRAVLRTAFAQRGLGLVLVGADPLRRPRRVNPGGRYSA 145 Query: 151 MEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMIAIAANSPML 210 ME FF IQ+NLDAGP+ GWA RVRLAHALGPTMIA ANSP+L Sbjct: 146 MEAFFTASGTGAAGAFMMTSTASIQLNLDAGPRRGWADRVRLAHALGPTMIAATANSPLL 205 Query: 211 GGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNPDAVAVTH 270 G FSGW+S+RQ VWG++D+ RCGP+LGAS DDPA+DWA YAL+APVMLVHNP+ V VT Sbjct: 206 AGRFSGWQSSRQWVWGELDEARCGPVLGASGDDPASDWARYALRAPVMLVHNPEPVPVTD 265 Query: 271 HVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFT 330 VPFA+W DG+ LLG RRPT +DL+YHLTTLFPPVRPR+WLEIRYLD++SD WPAV FT Sbjct: 266 WVPFAEWADGQTLLGGRRPTRSDLEYHLTTLFPPVRPRRWLEIRYLDAVSDALWPAVAFT 325 Query: 331 LVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXXXX 390 L TLLDDP AA++A EA + VAT WD AAR GLGD RLHAAA RCV Sbjct: 326 LTTLLDDPAAADIAAEATESVATAWDRAARIGLGDRRLHAAALRCVETAAERAPAAVMES 385 Query: 391 XQSLLAYVQRGRCPGDDFGDQVTEHGVAPAIARLARGE 428 Q L+ V+ GR P DDF D+ +G+ PA+ +LA+GE Sbjct: 386 MQQLVRSVEEGRSPADDFADRAVAYGIGPAVRQLAKGE 423 >tr|A1TGF5|A1TGF5_MYCVP Tax_Id=350058 SubName: Full=Glutamate--cysteine ligase, GCS2;[Mycobacterium vanbaalenii] Length = 424 Score = 514 bits (1324), Expect = e-144 Identities = 249/398 (62%), Positives = 293/398 (73%) Query: 31 QYIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPG 90 Q+I +GCL+DGP+G+VGLE+EAHC+D DP RRP W+E+ + L PGGS VTVEPG Sbjct: 26 QHIVDGCLIDGPVGQVGLEVEAHCFDLTDPSRRPGWDELTATITALPPLPGGSVVTVEPG 85 Query: 91 GAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQA 150 GAVELSGPP +AI AM D VLR+AFA AGLGLV +GADP+RP R+NPG RYQA Sbjct: 86 GAVELSGPPLAEPASAISAMAADHTVLRAAFARAGLGLVLVGADPLRPAARVNPGPRYQA 145 Query: 151 MEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMIAIAANSPML 210 ME FF +QVNL+AGP++GWA RVRLAHALGPTMIAIAANSP+L Sbjct: 146 MEAFFRASDSGDAGAAMMTSTASVQVNLEAGPRAGWADRVRLAHALGPTMIAIAANSPVL 205 Query: 211 GGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNPDAVAVTH 270 GG+F+GW+STRQ VW ++D RCGPILGAS DDPA+DWA YAL+APVMLVH+PD VT Sbjct: 206 GGDFTGWQSTRQLVWSRLDSARCGPILGASGDDPASDWARYALRAPVMLVHSPDPTPVTQ 265 Query: 271 HVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFT 330 VPFADW DGRVLL DR PT ADLDYHLTTLFPPVRPR +LE+RYLDS+ D WPAVV+T Sbjct: 266 WVPFADWADGRVLLDDRPPTLADLDYHLTTLFPPVRPRGFLEVRYLDSVPDATWPAVVYT 325 Query: 331 LVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXXXX 390 L TLLDDP AA++A EA + VAT WD AA+ GL D RLHAAA+RCV Sbjct: 326 LATLLDDPAAADVAAEATEEVATAWDRAAQLGLRDRRLHAAATRCVQAAADRAPRALEES 385 Query: 391 XQSLLAYVQRGRCPGDDFGDQVTEHGVAPAIARLARGE 428 L+ V++GR P DDF D+V HG+A A+ LA+GE Sbjct: 386 MGHLVRSVEQGRSPADDFADRVVAHGIADAVTELAQGE 423 >tr|A0R5N1|A0R5N1_MYCS2 Tax_Id=246196 SubName: Full=Glutamate--cysteine ligase; EC=6.3.2.2;[Mycobacterium smegmatis] Length = 423 Score = 511 bits (1316), Expect = e-143 Identities = 251/397 (63%), Positives = 288/397 (72%) Query: 32 YIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGG 91 +I L DGPIGRVGLEIEAHC+D ++P RRPSW+E+ V+ + PGGS +TVEPGG Sbjct: 26 HIGANSLQDGPIGRVGLEIEAHCFDLSNPTRRPSWDELSAVIADVPPLPGGSRITVEPGG 85 Query: 92 AVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAM 151 AVELSGPP DG LAA+ A+ D+AVLR+ FA LGLV LG DP+RPT R+NPGARY AM Sbjct: 86 AVELSGPPYDGPLAAVAALQADRAVLRAEFARRNLGLVLLGTDPLRPTRRVNPGARYSAM 145 Query: 152 EQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMIAIAANSPMLG 211 EQFF +QVNLDAGP+ GWA RVRLAHALGPTMIAI ANSPMLG Sbjct: 146 EQFFTASGTAEAGAAMMTATASVQVNLDAGPRDGWAERVRLAHALGPTMIAITANSPMLG 205 Query: 212 GEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNPDAVAVTHH 271 G+F+GW STRQRVWGQ+D RCGP+LG DDPA++WA YAL+APVMLV++PDAV VT+ Sbjct: 206 GQFTGWCSTRQRVWGQLDSARCGPVLGVDGDDPASEWARYALRAPVMLVNSPDAVPVTNW 265 Query: 272 VPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTL 331 VPFADW DGR +LG RRPT ADLDYHLTTLFPPVRPR+WLEIRYLDS+ D WPA VFTL Sbjct: 266 VPFADWADGRAVLGGRRPTEADLDYHLTTLFPPVRPRRWLEIRYLDSVPDALWPAAVFTL 325 Query: 332 VTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXX 391 TLLDDP AAE A EA +PVAT WD AAR GL D LH AA CV Sbjct: 326 TTLLDDPVAAESAAEATRPVATAWDRAARMGLTDRHLHTAALTCVRLAAERAPAELEESM 385 Query: 392 QSLLAYVQRGRCPGDDFGDQVTEHGVAPAIARLARGE 428 L+ VQ+ R P DDF D+V G+A A+ LA+GE Sbjct: 386 TLLMRSVQQRRSPADDFSDRVVARGIAAAVRELAKGE 422 >tr|A4T5Z6|A4T5Z6_MYCGI Tax_Id=350054 SubName: Full=Glutamate--cysteine ligase, GCS2;[Mycobacterium gilvum] Length = 448 Score = 506 bits (1304), Expect = e-141 Identities = 250/398 (62%), Positives = 289/398 (72%) Query: 31 QYIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPG 90 Q+I + CL D P G VGLEIEAHCYD +DP RRP W+E+ V+ L + PGGS VTVEPG Sbjct: 50 QHIVDTCLKDVPPGPVGLEIEAHCYDLSDPFRRPGWDELTAVIADLPRLPGGSLVTVEPG 109 Query: 91 GAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQA 150 GAVELSGPP G A+ AM D+AVLR FA AGLGLV LGADP+RP R+NPG+RY A Sbjct: 110 GAVELSGPPATGTADAVSAMVTDRAVLRDVFAGAGLGLVLLGADPLRPAGRVNPGSRYAA 169 Query: 151 MEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMIAIAANSPML 210 ME+FF +QVNL+AG ++GWA RVRLAHALGPTMIAIAANSP+L Sbjct: 170 MERFFAESGTPEAGAAMMTSTASVQVNLEAGHRAGWADRVRLAHALGPTMIAIAANSPVL 229 Query: 211 GGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNPDAVAVTH 270 G+F+GW STRQ VW Q+D RCGPILG DDPA+DWA YAL+APVMLVH P+AV VT Sbjct: 230 AGKFTGWHSTRQLVWSQLDSARCGPILGVDGDDPASDWARYALRAPVMLVHTPEAVPVTQ 289 Query: 271 HVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFT 330 VPFADW DGRVLL DRRPT ADLDYHLTTLFPPVRPR +LE+RYLDS+ D WPAVVFT Sbjct: 290 WVPFADWADGRVLLDDRRPTLADLDYHLTTLFPPVRPRGFLEVRYLDSVPDAVWPAVVFT 349 Query: 331 LVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXXXX 390 L TLLDDP AA++A EA +PVAT WD AA+ GL D RLH AA RCV Sbjct: 350 LSTLLDDPVAADVAAEATEPVATSWDRAAQLGLDDRRLHTAAVRCVYAAADRAPAALVES 409 Query: 391 XQSLLAYVQRGRCPGDDFGDQVTEHGVAPAIARLARGE 428 + L V++GR PGDDF D+V G+A A+ RLA+G+ Sbjct: 410 MELLTRSVEQGRSPGDDFADRVVNDGIAAAVTRLAQGD 447 >tr|C0U1D6|C0U1D6_9ACTO Tax_Id=526225 SubName: Full=Glutamate--cysteine ligase family protein;[Geodermatophilus obscurus DSM 43160] Length = 418 Score = 369 bits (947), Expect = e-100 Identities = 195/393 (49%), Positives = 236/393 (60%), Gaps = 5/393 (1%) Query: 32 YIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGG 91 ++A L GP+G VGLE+EAH D A P R W+ I +++ L PGGS VT+EPGG Sbjct: 20 HVAGAALRAGPVGSVGLELEAHLVDLAAPATRVPWQRITGIVDALPALPGGSRVTLEPGG 79 Query: 92 AVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAM 151 VELSGPP + AA+ A+ D+ VL +A L + +GADP+RP R+ P RY AM Sbjct: 80 QVELSGPPYPDVAAAVAALRADRDVLAAALVAERLAVAPVGADPLRPPARVCPAPRYAAM 139 Query: 152 EQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMIAIAANSPMLG 211 E+ F +QVNLDAGP +GW+ RV LAH LGPT++A+AA SP+ G Sbjct: 140 EEHFAAVGCAEAGTAMMAGTAALQVNLDAGPCAGWSERVSLAHQLGPTLVAVAACSPLAG 199 Query: 212 GEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNPD---AVAV 268 G +GW S RQRVW +D RCGP+LG + DPA +WA YAL APVMLV +PD A V Sbjct: 200 GRPTGWVSQRQRVWSDLDQARCGPLLGGA--DPAGEWAAYALAAPVMLVSDPDGGGAAPV 257 Query: 269 THHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVV 328 V FADWV G V LG R PT ADLDYHLTTLFPPVRPR +LEIRYLD+ + +WPA+ Sbjct: 258 RERVRFADWVTGAVPLGGRAPTAADLDYHLTTLFPPVRPRGYLEIRYLDAAPEPWWPALA 317 Query: 329 FTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXX 388 LLDDP AA A A PVA WD AAR GL DP LH AA C+ Sbjct: 318 AVTAVLLDDPVAAGHAAAATAPVAGAWDRAARVGLADPALHTAARTCLAAACAAVPVALR 377 Query: 389 XXXQSLLAYVQRGRCPGDDFGDQVTEHGVAPAI 421 ++L V RGRCPGD D G A+ Sbjct: 378 PEVEALADLVDRGRCPGDALLDTARAGGPTAAL 410 >tr|B1MFR8|B1MFR8_MYCA9 Tax_Id=561007 SubName: Full=Glutamate--cysteine ligase GshA;[Mycobacterium abscessus] Length = 416 Score = 364 bits (935), Expect = 1e-98 Identities = 187/394 (47%), Positives = 237/394 (60%), Gaps = 5/394 (1%) Query: 31 QYIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPG 90 ++IA D +G VGLE+E+H + PHRR +W + +V + + PG SA+T EPG Sbjct: 22 EHIARQAFADAQVGAVGLELESHTVELTAPHRRITWNRLREVGDSVPDLPGSSAITFEPG 81 Query: 91 GAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQA 150 GAVELSGPPC + +AI +M D +L + + AG+ L LG DP+R R+NPGARY A Sbjct: 82 GAVELSGPPCSDVWSAISSMRADHEILTAVYRGAGIALASLGTDPLRRPERVNPGARYVA 141 Query: 151 MEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMIAIAANSPML 210 ME+ F +QVN+ +G W R LA +GPTM A++A+SPML Sbjct: 142 MERHFGAAGYGETALQMMTCTASLQVNVQSGTPRQWRDRFVLAQRIGPTMAALSASSPML 201 Query: 211 GGEFSGWRSTRQRVWGQMDDGRCGPI-LGASADDPATDWAHYALKAPVMLVHNPD-AVAV 268 G +G R+TRQ +W +D RC P+ +G DP W YAL+APVMLV N D A AV Sbjct: 202 TGRPTGRRNTRQWIWDNLDPRRCAPVEIGV---DPTESWVEYALRAPVMLVRNKDGADAV 258 Query: 269 THHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVV 328 VPF WVDG + L R PT DLDYHLTTLFPPVRPR+WLE+RYLD+ D +WPA+ Sbjct: 259 VTRVPFQSWVDGTMPLAGRAPTTEDLDYHLTTLFPPVRPRRWLELRYLDAAPDWWWPALA 318 Query: 329 FTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXX 388 FT V LDDP A++A E +PV W AAR GL DP LHAAA R V Sbjct: 319 FTAVAALDDPQVADIAAEIAEPVGNAWGVAARIGLEDPALHAAAHRLVSAACAVAPPELA 378 Query: 389 XXXQSLLAYVQRGRCPGDDFGDQVTEHGVAPAIA 422 + LL V++GRCP DDF D VTE+GV A + Sbjct: 379 TDMEFLLERVEQGRCPADDFIDNVTEYGVEKAFS 412 >tr|D1ACB6|D1ACB6_THECU Tax_Id=471852 SubName: Full=Glutamate/cysteine ligase family protein;[Thermomonospora curvata DSM 43183] Length = 399 Score = 246 bits (628), Expect = 4e-63 Identities = 152/386 (39%), Positives = 187/386 (48%), Gaps = 18/386 (4%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP G+VG E E DPADP E + E G PG S +T EPGG +ELS Sbjct: 17 CFKTGPPGKVGAETEWLVIDPADPAAHVPLERVRAAAEAGGPLPGRSVITYEPGGQLELS 76 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 CDG+ +A+ +D A +R+ A GL LV G DP+R RY+ M +F Sbjct: 77 SRVCDGLADLHEALSQDLASVRARLAADGLDLVGRGVDPLRRPRLQAAHPRYRCMYDYFA 136 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQSGWA-SRVRLAHALGPTMIAIAANSPMLGGEFS 215 +QV LD G A R RLAHALGP ++A ANSP+ G + Sbjct: 137 GGGYRETGATMMCSTASVQVCLDIGADPADALRRWRLAHALGPVLVAAFANSPLRAGRRT 196 Query: 216 GWRSTRQRVWGQMDDGRCGPIL--GASADDPATDWAHYALKAPVMLVH----NPDAVAVT 269 G RSTRQ +W +D R P+L G DP W YA+ APVML D Sbjct: 197 GLRSTRQAIWAALDPCRTRPVLEAGTGPADPCRAWTRYAIDAPVMLTRPRPGTSDGWTGA 256 Query: 270 HHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVF 329 + F +W+D P D YHL+TLFPPVRPR WLE+R +D+L +WP V Sbjct: 257 PGMTFGEWMD------KGEPCLDDFAYHLSTLFPPVRPRGWLELRMIDALPLRYWPVPVA 310 Query: 330 TLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXXX 389 LLDDP A +A +A +PVA W AAR L DP L AA RC Sbjct: 311 VATALLDDPQAGRIAEDAARPVAGRWGAAARHALTDPALALAARRCFAAALQALPRLGAA 370 Query: 390 XXQSLLA-----YVQRGRCPGDDFGD 410 L+A YV+RGRCP DD D Sbjct: 371 ELVPLVADYARRYVERGRCPADDPAD 396 >tr|Q0RAS7|Q0RAS7_FRAAA Tax_Id=326424 (gshA)SubName: Full=Glutamate--cysteine ligase GSHA (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS); EC=6.3.2.2;[Frankia alni] Length = 523 Score = 235 bits (599), Expect = 9e-60 Identities = 156/408 (38%), Positives = 199/408 (48%), Gaps = 45/408 (11%) Query: 46 VGLEIEAHCYD------PADPHR-RPSWEEIGDVLEGLGKP--PGGSAVTVEPGGAVELS 96 VG+E E D P P R R + I ++ G P PGGS +T EPGG +ELS Sbjct: 98 VGIETEWFVVDTRVVHQPVPPERTRRALGRISGLITGAAGPVLPGGSRLTFEPGGQLELS 157 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 GPP G+ AA+ + D ++R+A A+ GL +V +G DP+R +R +RY AME+ F Sbjct: 158 GPPA-GLAAAVQSTAADLHLVRAALAEDGLAIVGMGVDPLRAGVRQTTASRYAAMEEHFR 216 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQSGWAS-RVRLAHALGPTMIAIAANSPMLGGEFS 215 +QVNLD G A+ R RLAHA+GP + A+ A SP L G + Sbjct: 217 TGGGTSGEVMMRSTAS-VQVNLDLGTTPAQAAERFRLAHAVGPVLTAMFAASPALAGRRT 275 Query: 216 GWRSTRQRVWGQMDDGRCGPIL-----------------GASADDPATDWAHYALKAPVM 258 GWRSTRQ VW +D GR G +L A + D A WA Y L A +M Sbjct: 276 GWRSTRQAVWSGIDAGRTGSVLDLPAQPAAGGDAGPGAAAARSGDLADRWARYLLAAKLM 335 Query: 259 LVHNPDA----------VAVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPR 308 ++ +P VA T F DWV GR + +R PT DL YH TTLFPPVRPR Sbjct: 336 MIGDPLGDVGPGEDRRFVAATGGHTFGDWVAGRGPV-ERAPTLDDLSYHATTLFPPVRPR 394 Query: 309 QWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRL 368 W E+RYLD+ W V LLDDP AA A + PVA W AA G+ D L Sbjct: 395 GWWELRYLDAQPAEGWRVAVAVATALLDDPVAAAAAAQVCAPVARRWPAAAMLGMADEPL 454 Query: 369 HAAASRCVXXXXXXXXXXXXXXXQSLL-----AYVQRGRCPGDDFGDQ 411 AA RC+ + Y QRGRCP D+ ++ Sbjct: 455 RLAAVRCLELAAAALRRAGCADLADAVELFSERYPQRGRCPADELSER 502 >tr|Q2J4D5|Q2J4D5_FRASC Tax_Id=106370 SubName: Full=Glutamate--cysteine ligase, GCS2; Flags: Precursor;[Frankia sp.] Length = 502 Score = 232 bits (591), Expect = 8e-59 Identities = 163/412 (39%), Positives = 199/412 (48%), Gaps = 40/412 (9%) Query: 42 PIGRVGLEIE--------AHCYDPADPHRR-PSWEEIGDVLEGLGKP--PGGSAVTVEPG 90 P G VG+E E HC P P R S I G G P PGGS +T EPG Sbjct: 82 PGGCVGIETEWLIVDTQAVHCLIP--PARTLASLARIPGTTPGPGGPVLPGGSRITFEPG 139 Query: 91 GAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQA 150 G +ELSGPP + + AA+ A D ++RSA A GL LV +G DP+R MR +RY A Sbjct: 140 GQLELSGPPAE-LTAAVRASSADLNLVRSALAVDGLALVGMGVDPLRVGMRQTTASRYAA 198 Query: 151 MEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASR-VRLAHALGPTMIAIAANSPM 209 ME+ F +QVNLD G A+R +L HALGP + A+ A SP Sbjct: 199 MEEHFRTGGGASGTVMMYSTAS-VQVNLDLGGSPAEAARRFQLVHALGPVLTALFAASPA 257 Query: 210 LGGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATD--------WAHYALKAPVMLVH 261 G +GWRSTRQ VW +D R P+ A + D WA Y L A +M+V Sbjct: 258 YAGRRTGWRSTRQAVWDGIDASRTRPVAAALTAPGSGDTEPDLVDLWARYLLDAKLMMVE 317 Query: 262 NPDAVAVT----HHVP------FADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWL 311 NP H VP F DW+ GR + R PT DL YH TT+FPPVRPR W Sbjct: 318 NPARAGNPEDDHHFVPVRDDSTFGDWLAGRGPV-TRPPTREDLSYHATTVFPPVRPRGWW 376 Query: 312 EIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAA 371 E+RYLD+ W A V LLDDP AA+ AFEA VA W AA G+ D L A Sbjct: 377 ELRYLDAQPGDGWQAAVAMPTVLLDDPVAADGAFEACLAVAHRWPAAAMLGMADEPLRRA 436 Query: 372 ASRCVXXXXXXXXXXXXXXXQSLL-----AYVQRGRCPGDDFGDQVTEHGVA 418 A RCV + Y+ RGRCP D+ +++ G A Sbjct: 437 AVRCVDLAVSALRRGGATDLAETVESFAGRYLDRGRCPADELTERLLAIGPA 488 >tr|A8L8S2|A8L8S2_FRASN Tax_Id=298653 SubName: Full=Glutamate--cysteine ligase GCS2;[Frankia sp.] Length = 472 Score = 229 bits (584), Expect = 5e-58 Identities = 162/444 (36%), Positives = 197/444 (44%), Gaps = 73/444 (16%) Query: 45 RVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKP------------------------- 79 RVG+E E D A+P R +E LE + P Sbjct: 18 RVGIETEWFVVDVANPRRPVPADETAAALESVLAPGDQGRQPDRGRENRGRENGQARDGG 77 Query: 80 ----------PGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLV 129 PGGS +T EPGG +ELSGPP D + AA+DAM D A++R A A LGLV Sbjct: 78 PPGTDSALRLPGGSRLTFEPGGQLELSGPPLD-LTAAVDAMRADLALVRGALARRRLGLV 136 Query: 130 CLGADPIRPTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWA-S 188 +G DP+R +R +RY AMEQ F +QVNLD G + A Sbjct: 137 GMGVDPLRTPVRHTTASRYVAMEQHF-LARDCDDGRTMMCSTASVQVNLDIGTDTAQAVE 195 Query: 189 RVRLAHALGPTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPIL----------- 237 R RLAHAL P +IA+ A SP+ G W+S RQ VW +D R GP+L Sbjct: 196 RFRLAHALEPVLIAMFAASPLAHGRQISWQSGRQAVWAGIDASRTGPVLPDPAAPATAWL 255 Query: 238 -----GASADDPATD----------WAHYALKAPVMLVHNPDA--VAVTHHVPFADWVDG 280 G D P WA Y A +M+V PD V + F DW+ G Sbjct: 256 AQAGPGGRGDAPGAPPTGDAQLAWLWARYLHDADLMMVGEPDGRYQPVRNRTTFGDWMAG 315 Query: 281 RVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGA 340 + R PT DL +H TTLFPPVRPR WLE+RYLD+ WP V LLD+P A Sbjct: 316 AGPVA-RPPTAQDLGWHATTLFPPVRPRGWLELRYLDAQPSDLWPVAVAVPAVLLDEPAA 374 Query: 341 AELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCVXXXXXXXXXXXXXXXQSLLA---- 396 A A A PVA + AA+ GL DP LH AA RCV Sbjct: 375 ARAALAACLPVARQGRLAAQLGLRDPALHRAAVRCVDLALDTLARTGADPGLRAAVEAFA 434 Query: 397 --YVQRGRCPGDDFGDQVTEHGVA 418 Y +RGR P DD + G A Sbjct: 435 NRYTRRGRSPADDLNARFEARGPA 458 >tr|C1YNM4|C1YNM4_NOCDA Tax_Id=446468 SubName: Full=Glutamate--cysteine ligase family protein;[Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length = 428 Score = 224 bits (572), Expect = 1e-56 Identities = 155/416 (37%), Positives = 198/416 (47%), Gaps = 31/416 (7%) Query: 31 QYIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPG 90 +YI C GP G+VG E E D ADP + + ++E G PP GS VT EPG Sbjct: 12 EYINGVCFKTGPPGKVGAETEWLVADSADPTAPVPVDRLAALVESCGPPPSGSGVTFEPG 71 Query: 91 GAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQA 150 G +ELS P G A A+ D + A A+AGL LV DP RP R ARY A Sbjct: 72 GQLELSSPALPGPARAHAALSADLDHVGKALAEAGLHLVETALDPARPPRRQLREARYTA 131 Query: 151 MEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSG-WASRVRLAHALGPTMIAIAANSPM 209 ME+FF +QV LD G + R L H LGP ++A ANS + Sbjct: 132 MERFF-AHHRQPSGYTMMCSTASLQVCLDTGEDAADVRDRWELVHRLGPVLVAAFANSAV 190 Query: 210 LGGEFSGWRSTRQRVWGQMDDGRCGPILGA-SADDPATDWAHYALKAPVMLVHNPDAV-A 267 G +GW+STR +W D R P+L A S DPAT WA YAL A VM V + Sbjct: 191 WRGRPTGWKSTRWAIWAATDATRTRPVLDAGSPADPATAWAEYALAARVMAVPGGEGPWT 250 Query: 268 VTHHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAV 327 V F+ W+DG+ G R T ADL++HL+TLFPPVRPR W E+R +D+L +WP Sbjct: 251 PDPGVTFSQWLDGQ---GPRPATRADLEFHLSTLFPPVRPRGWWELRMIDALPVRWWPVP 307 Query: 328 VFTLVTLLDDPGAAELAFEAVQ-------PVATEWDTAARAGLGDPRLHAAASRCVXXXX 380 V L+DDP A A EA + P W +AR G+ DP + A C Sbjct: 308 VALAAALVDDPRARAAAEEATEELCGGRSPDRHLWLRSARLGMADPDVARCARACFDAAI 367 Query: 381 XXXXXXXXXXXQSLLAYVQRGRCPGDDFGDQVTEHGVAPA-------IARLARGEQ 429 +L+ DD+ D T G++PA + R ARGE+ Sbjct: 368 EALPRMGAASLAALV----------DDYADHHTRRGLSPADTRPTVPVPRPARGER 413 >tr|C8XBM8|C8XBM8_NAKMY Tax_Id=479431 SubName: Full=Glutamate/cysteine ligase family protein;[Nakamurella multipartita] Length = 445 Score = 223 bits (568), Expect = 4e-56 Identities = 145/349 (41%), Positives = 187/349 (53%), Gaps = 18/349 (5%) Query: 40 DGPIGRVGLEIEAHCYDPAD-------PHRRPSWEEIGDVLEGL-GKPPGGSA---VTVE 88 +GP RVGLE+E D PH + I +++G PPGG VTVE Sbjct: 38 NGPPHRVGLELEFLVAGTGDDALATHYPHEQYP-HLIDRLIDGPPDSPPGGGLDGRVTVE 96 Query: 89 PGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARY 148 PGG VELS P D + A +D +H D A LR G LV LG DPIRP RI RY Sbjct: 97 PGGQVELSSRPGDSLAATVDTVHHDLARLRRRARGRGARLVGLGVDPIRPPRRITDQPRY 156 Query: 149 QAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAG-PQSGWASRVRLAHALGPTMIAIAANS 207 +AME++F +QVN++A P R L HA+GPT++A ANS Sbjct: 157 RAMERYFRPWGATGPAMMCSTAS--VQVNVEAATPAVDLHRRWELLHAIGPTLVAAFANS 214 Query: 208 PMLGGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNP-DAV 266 P G +G++STRQ +W ++D R G A +DPAT + ++L APVML+ D Sbjct: 215 PRRLGRATGFQSTRQAIWQELDPARTGAPPRAPGEDPATAFTRWSLDAPVMLIRREHDDW 274 Query: 267 AVTHHVPFADWV-DGRVLLGDR-RPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFW 324 + + W+ GR + DR PT DL YHL+TLFPPVRPR LEIRYLD+L +W Sbjct: 275 SAPPELSMRSWIRHGRRAVPDRPAPTVDDLAYHLSTLFPPVRPRGHLEIRYLDALPGCWW 334 Query: 325 PAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAAS 373 + LLDDP AA+ A +PV W TAAR+G+ DP L AA+ Sbjct: 335 IVPAAVIAALLDDPAAADQARATCEPVQEHWRTAARSGVRDPALGRAAT 383 >tr|C6WGZ9|C6WGZ9_ACTMD Tax_Id=446462 SubName: Full=Glutamate--cysteine ligase GCS2;[Actinosynnema mirum] Length = 408 Score = 216 bits (550), Expect = 5e-54 Identities = 144/357 (40%), Positives = 177/357 (49%), Gaps = 19/357 (5%) Query: 32 YIANGCLVDGPIGRVGLEIE---AHCYDPADPHRRPSWEE-IGDVLEGLGKP-------P 80 Y+A+ C GP +G+EIE H DP+ P + +GD P P Sbjct: 27 YVASVCFKHGPPRLIGVEIEWTVHHLGDPSLPVDAALFSAALGDHAPPTLVPDSPQRTLP 86 Query: 81 GGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTM 140 G+ +TVEPGG VE+S PP D + + + D L AG L GADP RP Sbjct: 87 SGTPLTVEPGGQVEISTPPRDSLTELLKTVASDVDHLAGLLEPAGFTLGDRGADPFRPPR 146 Query: 141 RINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTM 200 R+ RY+AM+ F +QV LDAG A+R AHALGP + Sbjct: 147 RLLDVPRYRAMQHAFDALGPDGLTMMCSTAG--LQVCLDAGEGPDVATRWAAAHALGPAL 204 Query: 201 IAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLV 260 +A+ ANSP +GG W S R R D RC P GA DDPA+ WA L APV++V Sbjct: 205 MALFANSPGVGGRRPDWASARMRTLYGTDPVRCRP--GAVCDDPASAWARRVLDAPVIVV 262 Query: 261 HNPDAVAVT-HHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL 319 P + H + FADWVDG + DRRPT DLDYHLT FPPVRPR +LEIRYLD+ Sbjct: 263 RRPGPDWIPPHRLTFADWVDGAL---DRRPTTEDLDYHLTLQFPPVRPRGYLEIRYLDTP 319 Query: 320 SDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRCV 376 W V L L P + EA P W TAAR GL DP L A++ V Sbjct: 320 GPGGWIPPVVLLAALFSHPSVVDSVLEATGPSVRRWLTAARHGLDDPVLARVAAQVV 376 >tr|B5I149|B5I149_9ACTO Tax_Id=463191 SubName: Full=Putative uncharacterized protein;[Streptomyces sviceus ATCC 29083] Length = 434 Score = 213 bits (543), Expect = 3e-53 Identities = 148/404 (36%), Positives = 192/404 (47%), Gaps = 34/404 (8%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP R+G+E+E ++ +P + E++ L P SA+TVEPGG +ELS Sbjct: 33 CFKTGPPRRIGVEVEWLVHELRNPRLPVTSEQLAAAYAALRAVPLKSALTVEPGGQLELS 92 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 P D ++ I + D A +R+A A+ GLGLV LG DP P R RY AME Sbjct: 93 SQPADSLMECIGTVSADLAAVRAALAEHGLGLVGLGHDPWHPPRRYLREPRYDAMEA--C 150 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQS----GWASRVRLAHALGPTMIAIAANSPMLGG 212 +QV +DAG + G R LAH LGP ++A ANSP+ G Sbjct: 151 LDRTGPAGRAMMCTSASVQVCVDAGHEEPGPLGLGRRWSLAHQLGPVLVAAFANSPLAGS 210 Query: 213 EFSGWRSTRQRVWGQMDDGRCGPILGASAD-DPATDWAHYALKAPVMLVHNPDAV-AVTH 270 E +GW STRQ W ++ GR G G S D DP + W + L APVM + + Sbjct: 211 EPTGWLSTRQLRWTEIGKGRAG---GPSLDTDPRSAWTRHVLDAPVMCIRRDSGPWDIPE 267 Query: 271 HVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL-SDVFWPAVVF 329 + F +W V R PT DLDYH++TLFPPVRPR LE+R +D+ + W + Sbjct: 268 GLSFREWARSGV---PRPPTREDLDYHVSTLFPPVRPRGHLELRMIDAQPGEDGWIVPLA 324 Query: 330 TLVTLLDDPGAAELAFEAVQPVATE-----------WDTAARAGLGDPRLHAAASRCVXX 378 L DDP AAE A+ V+P+A W AAR GL DP L AA C Sbjct: 325 VTAALFDDPQAAETAYRVVKPLAERTLSMPAPHNPLWIDAARHGLADPELCEAAIACFAA 384 Query: 379 XXXXXXXXXXXXXQS------LLAYVQRGRCPGDDFGDQVTEHG 416 + L YV RGRCP DD D+ HG Sbjct: 385 ALEALPRLGATTEVTDAVGAYLHRYVIRGRCPADDLLDRT--HG 426 >tr|C4E2X6|C4E2X6_STRRS Tax_Id=479432 SubName: Full=Glutamate--cysteine ligase family protein;[Streptosporangium roseum DSM 43021] Length = 408 Score = 209 bits (533), Expect = 4e-52 Identities = 144/345 (41%), Positives = 169/345 (48%), Gaps = 20/345 (5%) Query: 34 ANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAV 93 A C +VG+E+E +D P + L L PGGS VT EPGG + Sbjct: 21 ARNCFHGSAGDQVGVELEFLVFDRTSPDCHVPLARVAGALPPL---PGGSRVTFEPGGQL 77 Query: 94 ELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQ 153 ELSGP + AI + D R+A +AGL L +G DPIRP R RY+AM + Sbjct: 78 ELSGP-AGPLPEAIARLAADVDAARAALREAGLVLAGVGLDPIRPARRQLRLPRYEAMAE 136 Query: 154 FFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMIAIAANSPMLGGE 213 F IQVNLD G + A R AH LGP + A ANSP+ GG Sbjct: 137 FLGTPYGSLMMCSTAS----IQVNLDLGDRP--AVRWERAHLLGPVLTAAFANSPLSGGR 190 Query: 214 FSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVH-NPDAV-AVTHH 271 GW S RQ VW +D R P+ + DPA WA Y L A +MLV N D V Sbjct: 191 PCGWMSGRQAVWENLDRTRTAPV--PATGDPAAAWAEYLLDARLMLVRENGDRCRTVRDG 248 Query: 272 VPFADWVDGRVLLGDRRP-TYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDVFWPAVVFT 330 F DW L RP T ADL YH TT+FPPVRPR WLEIRYLD+ WP V Sbjct: 249 STFRDW-----LAAPARPLTLADLAYHATTIFPPVRPRGWLEIRYLDAQRPADWPVCVAV 303 Query: 331 LVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRC 375 L+ D AAE A A +P A W AAR GL +PRL AA C Sbjct: 304 THALVMDDRAAETAIAAAEPYAGMWPGAARHGLAEPRLRKAAETC 348 >tr|A0ADU7|A0ADU7_STRAM Tax_Id=278992 SubName: Full=Putative glutamate-cysteine ligase;[Streptomyces ambofaciens ATCC 23877] Length = 433 Score = 208 bits (530), Expect = 9e-52 Identities = 148/399 (37%), Positives = 187/399 (46%), Gaps = 34/399 (8%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP R+G+E+E ++ +P S E + V L P SA+TVEPGG +ELS Sbjct: 28 CFKTGPPTRLGVEVEWLVHELREPRLPVSPERLDAVYTALRAVPLRSALTVEPGGQLELS 87 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 P + +D + D A +R+ + GLGLV LG DP + R RY AME Sbjct: 88 SLPAASLTECVDTVSADLAAVRAVLREDGLGLVGLGHDPWQVPRRFLRQPRYDAMEA--C 145 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQS----GWASRVRLAHALGPTMIAIAANSPMLGG 212 +QV LDAG + G R LAH LG ++A ANSP+ GG Sbjct: 146 LDRGGPAGRYMMCTSASVQVCLDAGHEEPGPLGHVRRWWLAHQLGAVLLAAFANSPLAGG 205 Query: 213 EFSGWRSTRQRVWGQMDDGRCGPILGASAD-DPATDWAHYALKAPVMLVHNPDAV-AVTH 270 +GWRSTRQ W Q+ GR G G + D DP W + L APVM V V Sbjct: 206 RLTGWRSTRQLRWAQIGPGRAG---GPALDTDPRGTWTRHVLDAPVMCVRRDGGPWDVPE 262 Query: 271 HVPFADWV-DGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL-SDVFWPAVV 328 + F +W+ GR R PT DLDYHLTTLFPPVRPR LE+R +D+ D W + Sbjct: 263 GLTFREWIRSGR----PRPPTLEDLDYHLTTLFPPVRPRGHLELRMIDAQPGDDGWRVPL 318 Query: 329 FTLVTLLDDPGAAELAFEAVQPVATE-----------WDTAARAGLGDPRLHAAASRCVX 377 L DDP A E A+ AV+P+ ++ AAR L DP L AA C Sbjct: 319 AVTAALFDDPEATETAYRAVKPLTERTLGRPAPHNPLYEDAARDALTDPELREAAVTCFE 378 Query: 378 XXXXXXXXXXXXXXQS------LLAYVQRGRCPGDDFGD 410 + L YV+RGRCP DD D Sbjct: 379 AALAALPRLGATTEVTDAVAGHLERYVRRGRCPADDLLD 417 >tr|C9NJF2|C9NJF2_9ACTO Tax_Id=591167 SubName: Full=Glutamate/cysteine ligase family protein;[Streptomyces flavogriseus ATCC 33331] Length = 432 Score = 205 bits (521), Expect = 1e-50 Identities = 142/404 (35%), Positives = 185/404 (45%), Gaps = 31/404 (7%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP VG+E+E +D P + + + + P +A+T EPGG +ELS Sbjct: 31 CFKTGPPRTVGVELEWLVHDREHPEALVPEDRLRAAADAVRATPLDAALTFEPGGQLELS 90 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 P ++ +DA D A +R +GL L +G DP P R+ RY AME Sbjct: 91 SQPKGSLMECVDATAADLAAVRDTLGRSGLTLAGIGVDPWNPPRRLLREPRYDAMEA--A 148 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQS----GWASRVRLAHALGPTMIAIAANSPMLGG 212 +QV LDAG + G+ R +L H LG ++A A+SP G Sbjct: 149 LDRSGSAGRAMMCTSASVQVCLDAGEEEPGPLGYGRRWQLGHLLGAVLVAAFAHSPFRQG 208 Query: 213 EFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNPDAV-AVTHH 271 +GW+STRQ +W +D R + DP WA + L PVM V N + V Sbjct: 209 RRTGWQSTRQALWADLDPAR--TLAPQGRLDPRDAWAAHVLATPVMCVRNTEGPWDVPEA 266 Query: 272 VPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDV-FWPAVVFT 330 + F DW+ G G R P ADLDYHLTTLFPPVRPR LE+R +D+ S W + Sbjct: 267 LTFRDWIRGG---GPRPPVRADLDYHLTTLFPPVRPRGHLELRMIDAQSGTDGWLVPLAV 323 Query: 331 LVTLLDDPGAAELAFEAVQPVATE-----------WDTAARAGLGDPRLHAAASRC--VX 377 L DDP AAE + V+P+A W AAR GL DP L AAA+ C Sbjct: 324 TTALFDDPEAAETVYRTVKPLAETAGLPPAPRNPLWTAAARDGLRDPELAAAAAACFTTA 383 Query: 378 XXXXXXXXXXXXXXQSLLA----YVQRGRCPGDDFGDQVTE-HG 416 ++ A YV RGRCP DD D E HG Sbjct: 384 LEALPRMGASGHVLGTVAAFHERYVARGRCPADDLPDPAQEPHG 427 >tr|Q8GPN7|Q8GPN7_STRAW Tax_Id=33903 SubName: Full=Putative uncharacterized protein;[Streptomyces avermitilis] Length = 432 Score = 199 bits (505), Expect = 7e-49 Identities = 141/396 (35%), Positives = 184/396 (46%), Gaps = 36/396 (9%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP +G+E+E ++ P + E + L P SA+TVEPGG +ELS Sbjct: 36 CFKTGPPRTLGVELEWIVHELRRPQLPVAPERLDAAYAALRTVPLRSALTVEPGGQLELS 95 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 P ++ I ++ D +R+ +AGLGL G DP P R RY AME + Sbjct: 96 SAPAASLMECIGSVSADLDAVRALLREAGLGLRGYGHDPWSPPTRYLHEPRYDAMESYL- 154 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQS----GWASRVRLAHALGPTMIAIAANSPMLGG 212 +QV LDAG + G R LAH LG ++A A+SPM G Sbjct: 155 -DRAGPEGRAMMCSSASVQVCLDAGHEEPGPLGHGRRWWLAHHLGAVLVAAFAHSPMAHG 213 Query: 213 EFSGWRSTRQRVWGQMDDGRCG--PILGASADDPATDWAHYALKAPVMLVH-NPDAVAVT 269 +GWRSTRQ +W MD GR P+ G DP WA + L APVM + + V Sbjct: 214 RATGWRSTRQYLWAAMDPGRSSAPPLDG----DPRRTWARHVLDAPVMCIRADSGPWQVP 269 Query: 270 HHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL-SDVFWPAVV 328 + F +W P DLDYH++TLFPPVRPR +LE+R +D+ D W + Sbjct: 270 EAMSFREWT-----RSGTPPDRGDLDYHVSTLFPPVRPRGYLELRMIDAQPGDDGWIVPL 324 Query: 329 FTLVTLLDDPGAAELAFEAVQPVATE-----------WDTAARAGLGDPRLHAAASRC-V 376 L DDP AAE+A+ V+P+A W AAR GL DP LH AA C Sbjct: 325 AVTAALFDDPEAAEIAYRTVKPLAEHGRSLPAPCNPLWIEAARQGLADPELHEAAVICFA 384 Query: 377 XXXXXXXXXXXXXXXQSLLA-----YVQRGRCPGDD 407 Q+ +A YV RGRCP DD Sbjct: 385 AAAEALPRLGATAEVQNAVAEFTDRYVARGRCPADD 420 >tr|Q825V6|Q825V6_STRAW Tax_Id=33903 (gshA)SubName: Full=Putative glutamate-cysteine ligase;[Streptomyces avermitilis] Length = 424 Score = 197 bits (502), Expect = 2e-48 Identities = 141/396 (35%), Positives = 183/396 (46%), Gaps = 36/396 (9%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP +G+E+E ++ P + E + L P SA+TVEPGG +ELS Sbjct: 28 CFKTGPPRTLGVELEWIVHELRRPQLPVAPERLDAAYAALRTVPLRSALTVEPGGQLELS 87 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 P ++ I ++ D +R+ +AGLGL G DP P R RY AME + Sbjct: 88 SAPAASLMECIGSVSADLDAVRALLREAGLGLRGYGHDPWSPPTRYLHEPRYDAMESYL- 146 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQS----GWASRVRLAHALGPTMIAIAANSPMLGG 212 +QV LDAG + G R LAH LG ++A A+SPM G Sbjct: 147 -DRAGPEGRAMMCSSASVQVCLDAGHEEPGPLGHGRRWWLAHQLGAVLVAAFAHSPMAHG 205 Query: 213 EFSGWRSTRQRVWGQMDDGRCG--PILGASADDPATDWAHYALKAPVMLVH-NPDAVAVT 269 +GWRSTRQ +W MD GR P+ G DP WA + L APVM + + V Sbjct: 206 RATGWRSTRQYLWAAMDPGRSSAPPLDG----DPRRTWARHVLDAPVMCIRADSGPWQVP 261 Query: 270 HHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL-SDVFWPAVV 328 + F +W P DLDYH++TLFPPVRPR LE+R +D+ D W + Sbjct: 262 EAMSFREWT-----RSGTPPDRGDLDYHVSTLFPPVRPRGHLELRMIDAQPGDDGWIVPL 316 Query: 329 FTLVTLLDDPGAAELAFEAVQPVATE-----------WDTAARAGLGDPRLHAAASRC-V 376 L DDP AAE+A+ V+P+A W AAR GL DP LH AA C Sbjct: 317 AVTAALFDDPEAAEIAYRTVKPLAEHGRSLPAPCNPLWIEAARQGLADPELHEAAVICFA 376 Query: 377 XXXXXXXXXXXXXXXQSLLA-----YVQRGRCPGDD 407 Q+ +A YV RGRCP DD Sbjct: 377 AAAEALPRLGATAEVQNAVAEFTDRYVARGRCPADD 412 >tr|B1VRV6|B1VRV6_STRGG Tax_Id=455632 SubName: Full=Putative glutamylcysteine synthetase;[Streptomyces griseus subsp. griseus] Length = 456 Score = 196 bits (497), Expect = 6e-48 Identities = 136/394 (34%), Positives = 181/394 (45%), Gaps = 30/394 (7%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP VG+E+E +D P E + +E + P +A+T EPGG +ELS Sbjct: 31 CFKTGPPRTVGVELEWLIHDRERPDLPVGQERLDRAVEAVRALPLSAALTFEPGGQLELS 90 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 P ++ +D D A +R+A AGL V LG DP + +R RY+AME Sbjct: 91 SQPAGSLMECVDTTAADLAAVRAALDTAGLAPVGLGVDPWQAPLRRLREPRYEAMEA--A 148 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQS----GWASRVRLAHALGPTMIAIAANSPMLGG 212 +QV LDAG + G+ R +LAH LG ++A ANSP G Sbjct: 149 LDRTGPAGRAMMCTSASVQVCLDAGEEEPGPLGYGRRWQLAHLLGAVLVAAFANSPFRQG 208 Query: 213 EFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLVHNPDAV-AVTHH 271 +GWRSTRQ +W +D R + S P WA + L V+ + + V Sbjct: 209 RRTGWRSTRQSLWADLDPVR--TLAPGSGRAPREAWAAHVLDTTVLCIRREEGPWEVPEG 266 Query: 272 VPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSDV-FWPAVVFT 330 + F +W+ R P ADLDYHLTTLFPPVRPR LE+R +D+ S W + Sbjct: 267 LTFREWIRTG---SPRPPVRADLDYHLTTLFPPVRPRGHLELRMIDAQSGPDGWLVPLAV 323 Query: 331 LVTLLDDPGAAELAFEAVQPVATE-----------WDTAARAGLGDPRLHAAASRC--VX 377 L DDP AAE + ++P+A W TAAR GL DP L AA+ C Sbjct: 324 ATALFDDPEAAETVYRTLKPLAEASDASAAPRNALWTTAAREGLADPELRGAATACFGAA 383 Query: 378 XXXXXXXXXXXXXXQSLLA----YVQRGRCPGDD 407 ++ A YV RGRCP DD Sbjct: 384 LPALERMGASGAVRDTVAAFTDRYVARGRCPADD 417 >tr|B4V5Z6|B4V5Z6_9ACTO Tax_Id=465541 SubName: Full=Glutamate-cysteine ligase;[Streptomyces sp. Mg1] Length = 458 Score = 195 bits (496), Expect = 8e-48 Identities = 133/362 (36%), Positives = 172/362 (47%), Gaps = 31/362 (8%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP +G E+E D P + E + E G P S +TVEPGG +ELS Sbjct: 52 CFKTGPPRILGAELEWLVLDAERPGLPLAPERLTAAHEAAGALPLHSRLTVEPGGQLELS 111 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 P D + A +D + D +R GL L LG DP RP R+ RY+AME++ Sbjct: 112 SAPADSLSACVDGLQADLTAVRGVLHAQGLVLRGLGQDPRRPYRRLLTDPRYEAMERYL- 170 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQS----GWASRVRLAHALGPTMIAIAANSPMLGG 212 +QV +DAG + G R RLAH LG ++A ANSP + G Sbjct: 171 -DRAGPAGRAMMCASASVQVCVDAGHEEPGPLGHGRRWRLAHLLGAVLVAAFANSPAVDG 229 Query: 213 EFSGWRSTRQRVWGQMDDGRCGPILGASAD-DPATDWAHYALKAPVMLVHNPDAV----- 266 ++GWR RQ VW +D GR L D +P W +AL VM V P+ Sbjct: 230 PYAGWRCARQGVWEDLDSGRS---LAPPLDIEPRAAWTRHALDTRVMCVRAPEGAPEDTP 286 Query: 267 -AVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL-SDVFW 324 V + F DW+ G R T DL+YHLTTLFPPVRPR LE+R +D+ D W Sbjct: 287 WTVPEGLTFRDWIRTG---GPRPATAGDLEYHLTTLFPPVRPRGHLELRMIDAQPGDDGW 343 Query: 325 PAVVFTLVTLLDDPGAAELAFEAVQPVATE-----------WDTAARAGLGDPRLHAAAS 373 V + L DDP AAE A+ + +A W +AARAGL DP L +AA+ Sbjct: 344 LVPVAVVHALFDDPEAAETAYRVSKALADSYGPHAAPRNPLWRSAARAGLADPELRSAAT 403 Query: 374 RC 375 C Sbjct: 404 AC 405 >tr|C1WR11|C1WR11_9ACTO Tax_Id=479435 SubName: Full=Gamma-glutamylcysteine synthetase;[Kribbella flavida DSM 17836] Length = 408 Score = 194 bits (494), Expect = 1e-47 Identities = 136/361 (37%), Positives = 170/361 (47%), Gaps = 27/361 (7%) Query: 32 YIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGK------------- 78 Y+A C GP G+E+E + DPHR + G + + LG Sbjct: 22 YVAMVCFKHGPPRLHGVELEWTVHHADDPHRPL---DAGQLSKALGAHAPATLVRGSPQL 78 Query: 79 PPG-GSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIR 137 P G G+ VTVEPGG VE+SGP + I+ D A L S A GL G D R Sbjct: 79 PLGRGALVTVEPGGQVEISGPASASVPGLIEDTAADAAQLTSLLAAGGLVPGDHGLDAFR 138 Query: 138 PTMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALG 197 P R+ RY AME+ +QV LDAG A+R R H +G Sbjct: 139 PPRRLLTVPRYAAMERALQQLGPHGPRMMCSTAG--LQVCLDAGEPGQTATRWRALHDIG 196 Query: 198 PTMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGASADD--PATDWAHYALKA 255 P M+A+ ANS G +GW S R + G C P D PA WA A++A Sbjct: 197 PAMVALFANSRQRAGANTGWASART----EATFGTCAPFTEPPTQDGDPAEAWARTAMEA 252 Query: 256 PVMLVHNPDAVAVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRY 315 PV+ + D+ + F W DG L GDR PTY DLDYHL+TLFPPVRPR +LE+RY Sbjct: 253 PVLCLRRGDSWDAPAGLSFGAWADG-ALPGDR-PTYDDLDYHLSTLFPPVRPRGYLEVRY 310 Query: 316 LDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAASRC 375 LD+ W L+ LL DP + A A P A W AAR GL D +H AA+ Sbjct: 311 LDAQRGDDWIPPTLLLIALLSDPAVTDQALAAAAPAAGRWFPAARHGLDDKLVHQAAAEL 370 Query: 376 V 376 V Sbjct: 371 V 371 >tr|Q9RD01|Q9RD01_STRCO Tax_Id=1902 SubName: Full=Putative uncharacterized protein SCO0910;[Streptomyces coelicolor] Length = 433 Score = 190 bits (483), Expect = 3e-46 Identities = 145/398 (36%), Positives = 183/398 (45%), Gaps = 32/398 (8%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP +G+E+E ++ P S E + V L P SA+TVEPGG +ELS Sbjct: 28 CFKTGPPRLLGVEVEWLVHELRAPRLPVSPERLQAVYTALRAVPLRSALTVEPGGQLELS 87 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 P + + ++ D +R+ + GL LV LG DP P R RY AME Sbjct: 88 SLPAASLTECVRSVSADLEAVRAVLREDGLALVGLGHDPWHPPRRYLRQPRYDAMES--C 145 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQS----GWASRVRLAHALGPTMIAIAANSPMLGG 212 +QV +DAG + G R LAH LG ++A ANSP+ GG Sbjct: 146 LDRTGPGGRFMMCASASVQVCVDAGHEEPGPLGHVRRWWLAHHLGAVLLAAFANSPLSGG 205 Query: 213 EFSGWRSTRQRVWGQMDDGRCGPILGASAD-DPATDWAHYALKAPVMLVHNPDAV-AVTH 270 +GWRSTRQ W Q+ GR G G D DP WA + L APVM V V Sbjct: 206 RPTGWRSTRQLRWTQIGAGRAG---GPPLDSDPRGTWARHVLDAPVMCVRRDGGPWDVPE 262 Query: 271 HVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL-SDVFWPAVVF 329 + +W R L+ R PT DLDYHLTTLFPPVRPR LE+R +D+ D W + Sbjct: 263 GLTLREW--SRELV-PRPPTREDLDYHLTTLFPPVRPRGHLELRMIDAQPGDDGWIVPLA 319 Query: 330 TLVTLLDDPGAAELAFEAVQPVATE-----------WDTAARAGLGDPRLHAAASRC--V 376 L DDP A E A+ AV+P+A ++ AAR L DP L AA C Sbjct: 320 VTAALFDDPEATETAYRAVKPLAERTLGLPAPHNPLYEDAARDALTDPELREAAVTCFTA 379 Query: 377 XXXXXXXXXXXXXXXQSLLA----YVQRGRCPGDDFGD 410 ++ A YV RGRCP DD D Sbjct: 380 ALAALPRLGASTEVTDAVAAYRERYVLRGRCPADDLLD 417 >tr|C9Z4Y5|C9Z4Y5_STRSW Tax_Id=680198 SubName: Full=Putative uncharacterized protein;[Streptomyces scabies] Length = 424 Score = 190 bits (483), Expect = 3e-46 Identities = 138/398 (34%), Positives = 182/398 (45%), Gaps = 34/398 (8%) Query: 37 CLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPGGAVELS 96 C GP +G+E+E H ++ DP + + L S +TVEPGG +ELS Sbjct: 28 CFKTGPPRTLGVELEWHVHELRDPRLPATPARLAAAYAALRTLTLNSPLTVEPGGQLELS 87 Query: 97 GPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQAMEQFFX 156 P + ID++ D A +R+ +A LG+ G +P P R RY AME + Sbjct: 88 SAPAASLTECIDSVSADLAAVRATLREADLGISGYGHEPWNPPTRYLHEPRYDAMEIYL- 146 Query: 157 XXXXXXXXXXXXXXXXXIQVNLDAGPQS----GWASRVRLAHALGPTMIAIAANSPMLGG 212 +QV LDAG + G R LAH LG ++A A+SP+ G Sbjct: 147 -RRFGPEGLAMMCSTASVQVCLDAGYEEPGPLGHRRRWWLAHQLGAVLVAAFAHSPLARG 205 Query: 213 EFSGWRSTRQRVWGQMDDGR-CGPILGASADDPATDWAHYALKAPVMLVHNPDAV-AVTH 270 +G RSTRQ +W MD GR P L DP WA L APVM V + V Sbjct: 206 RVTGLRSTRQALWAAMDPGRTTAPDLDG---DPREAWARLVLDAPVMCVRADEGPWGVPG 262 Query: 271 HVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL-SDVFWPAVVF 329 + F +W D P+ ADLDYHLTTLFPPVRPR LE+R +D+ + W + Sbjct: 263 AMTFREWTG-----TDNPPSRADLDYHLTTLFPPVRPRGHLELRMIDAQPGEDGWIVPLA 317 Query: 330 TLVTLLDDPGAAELAFEAVQPVATE-----------WDTAARAGLGDPRLHAAASRC--V 376 L +DP AAE+A+ V+P+A W+ A R GL DP L AA+ C Sbjct: 318 VTTALFEDPEAAEIAYRTVKPLAERAGSQPPPRNPLWEAATRDGLTDPDLREAAAVCFAA 377 Query: 377 XXXXXXXXXXXXXXXQSLLA----YVQRGRCPGDDFGD 410 ++ A YV RGRCP DD D Sbjct: 378 AAEALPRLGAGTEVLDAVAAYTDRYVARGRCPADDLLD 415 >tr|C7MXH6|C7MXH6_SACVD Tax_Id=471857 SubName: Full=Gamma-glutamylcysteine synthetase;[Saccharomonospora viridis] Length = 428 Score = 187 bits (475), Expect = 2e-45 Identities = 130/355 (36%), Positives = 162/355 (45%), Gaps = 19/355 (5%) Query: 32 YIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVL----------EGLGKP-P 80 Y+A+ C GP +G+E+E +D DP S + D L + +P P Sbjct: 41 YVASVCFKHGPPRLLGVELEYTVHDAVDPGLPLSRTRLADALGPYAPRTLVPDSPEQPLP 100 Query: 81 GGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTM 140 GS T+EPGG E+S P A +A D A + A GL L G DP RP Sbjct: 101 AGSTFTLEPGGQAEISTAPHSSFRALCEAADADLAYVADLLAATGLRLGSRGIDPFRPPK 160 Query: 141 RINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTM 200 R+ RY AME+ F +QV +D G R AHALGP + Sbjct: 161 RLLHTPRYAAMERRFAPAGTGGITMMCSTAA--LQVCVDTGQPHELPHRWAAAHALGPVL 218 Query: 201 IAIAANSPMLGGEFSGWRSTRQRVW-GQMDDGRCGPILGASADDPATDWAHYALKAPVML 259 +A+ ANS G +G S R W MD C + DPA WA L P++L Sbjct: 219 LALFANSRWHAGVDTGCASAR---WLAVMDTDTCRTAAQRTGGDPAEAWARRVLDTPLLL 275 Query: 260 VHNPDAV-AVTHHVPFADWVDGR-VLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLD 317 + D + FADW+DG RPT ADLDYHLTTLF PVRP +LE+RYLD Sbjct: 276 LRRDDGPWDAPSELTFADWIDGGGAATSLPRPTLADLDYHLTTLFTPVRPHGYLELRYLD 335 Query: 318 SLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAA 372 + W V L L E E +PVA W AAR GLGDPR+ AAA Sbjct: 336 AQPLESWEHPVALLAALFSRQSLVESVLEVCEPVADRWSEAARHGLGDPRIAAAA 390 >tr|C1AY21|C1AY21_RHOOB Tax_Id=632772 (gshA)SubName: Full=Putative glutamate--cysteine ligase; EC=6.3.2.2;[Rhodococcus opacus] Length = 404 Score = 170 bits (430), Expect = 4e-40 Identities = 127/355 (35%), Positives = 159/355 (44%), Gaps = 21/355 (5%) Query: 32 YIANGCLVDGPIGRVGLEIE---AHCYDPADPHRRPSWEEIGDVLEGLGKP-------PG 81 Y+ C GP +G E+E A + P E +G P PG Sbjct: 22 YLGGVCFKLGPPQLIGAELEWLTAQLPEYLRPDLAALAEALGPHTPRTIDPASPARLLPG 81 Query: 82 GSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMR 141 GSAVTVEPGG +ELS P D + DQAVL + + + AD RP R Sbjct: 82 GSAVTVEPGGQIELSSAPYHSARELCDYLAADQAVLAKLLSSRSILMSAEAADTRRPAQR 141 Query: 142 INPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMI 201 + RY AME F I V+ A P + +R L HA+GP +I Sbjct: 142 LLQSPRYCAMESRFTGIGPFGKLMMCNTAATQISVDAGADPVAV-ETRWHLLHAVGPALI 200 Query: 202 AIAANSPMLGGEFSG-WRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLV 260 A A SP L G G W S R R W ++D R + + D+A + L P++ + Sbjct: 201 AAFACSPRLYGVPDGQWASQRMRTWLELDSPR------TTGTPHSADYAAWVLDVPLLCI 254 Query: 261 HN--PDAVAVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDS 318 N PD A FADW +G + RPT ADLDYHLTTLFPPVR LE+RYLD+ Sbjct: 255 RNDGPDWTA-PDGATFADWAEGALDDMIGRPTSADLDYHLTTLFPPVRAAGHLEVRYLDA 313 Query: 319 LSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAAS 373 W + + LL PGA A A P A W AA GL D L AAA+ Sbjct: 314 QPGDQWRVPIAAIDALLSGPGAMAEALAAALPTAERWRDAAEFGLADLELRAAAT 368 >tr|A4FGC2|A4FGC2_SACEN Tax_Id=405948 (gshA)SubName: Full=Glutamate-cysteine ligase;[Saccharopolyspora erythraea] Length = 412 Score = 170 bits (430), Expect = 4e-40 Identities = 125/354 (35%), Positives = 159/354 (44%), Gaps = 21/354 (5%) Query: 32 YIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKP-----------P 80 Y+A C GP G+E+E + DP R E + L P P Sbjct: 27 YVATVCFKTGPPRLHGIELEWTVHHDDDPSRPLDPEVLISALGPHAPPSLVPGSPHRPLP 86 Query: 81 GGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTM 140 GS++TVEPGG VE+S P + + D + D LR +GL L G DP R Sbjct: 87 NGSSLTVEPGGQVEVSSLPSPSVRSLFDVVAADADHLRRLLRPSGLSLGEQGTDPWRHPR 146 Query: 141 RINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTM 200 R+ RY AME F +QV LDAG A R HALGP M Sbjct: 147 RVLQVPRYAAMESAFDRIGIDGRLMMCSTAG--VQVCLDAGEPHRIAPRWAALHALGPVM 204 Query: 201 IAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLV 260 +A ANSP L G +GW STR R + D R P G + DPAT WA L ++ + Sbjct: 205 LATFANSPKLFGHDTGWLSTRTRAVLRTDPPRTRP--GPVSPDPATGWARRMLDTALVCL 262 Query: 261 HNPDAV--AVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDS 318 D V V + FA+W+ G L G PT DLDYH++T+FPPVR R +LE+RYLD+ Sbjct: 263 RR-DGVDWTVPGGISFAEWISG-ALAGP--PTMDDLDYHMSTVFPPVRARGYLEVRYLDA 318 Query: 319 LSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAA 372 W L+ L + + W AAR GL DP L + A Sbjct: 319 QPGDDWMLPAAALIALFEAESTVDEVLRLTARTPGRWMHAARHGLADPVLASTA 372 >tr|Q0S4Q7|Q0S4Q7_RHOSR Tax_Id=101510 SubName: Full=Probable glutamate--cysteine ligase; EC=6.3.2.2;[Rhodococcus sp.] Length = 404 Score = 166 bits (421), Expect = 4e-39 Identities = 124/354 (35%), Positives = 155/354 (43%), Gaps = 19/354 (5%) Query: 32 YIANGCLVDGPIGRVGLEIE---AHCYDPADPHRRPSWEEIG-------DVLEGLGKPPG 81 Y+ C GP +G E+E A + P E +G D PG Sbjct: 22 YLGGVCFKLGPPQLIGAELEWLTAQLPEYVRPDLAALAEALGPHTPRTIDPTSPAQPLPG 81 Query: 82 GSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMR 141 GSAVTVEPGG +ELS P D + DQAVL + + + AD RP R Sbjct: 82 GSAVTVEPGGQIELSSAPYYSARELCDYLAADQAVLTDLLSSRSILMSSEAADTRRPAQR 141 Query: 142 INPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTMI 201 + RY AME F I V+ A P + R L HA+GP +I Sbjct: 142 LLQSPRYCAMESRFTGIGPFGKLMMCNTAATQISVDAGADPVAV-EKRWHLLHAIGPALI 200 Query: 202 AIAANSPMLGGEFSG-WRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLV 260 A A SP L G G W S R R W ++D R D+A + L P++ + Sbjct: 201 AAFACSPRLYGVPDGQWASQRMRTWLELDSPR------TIGTPHVADYAGWVLDVPLLCI 254 Query: 261 HNPDAV-AVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL 319 N FADWV+G + RPT ADLDYHLTTLFPPVR LE+RYLD+ Sbjct: 255 RNDGTDWTAPDGATFADWVEGALDDVIGRPTPADLDYHLTTLFPPVRAAGHLEVRYLDAQ 314 Query: 320 SDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAAS 373 W + + LL PGA A +A P A W AA GL + L AAA+ Sbjct: 315 PGDQWRVPIAAIDALLSGPGAMAEALDAALPTAERWRDAAEFGLAELELRAAAT 368 >tr|A4X6R4|A4X6R4_SALTO Tax_Id=369723 SubName: Full=Glutamate--cysteine ligase, GCS2;[Salinispora tropica] Length = 410 Score = 165 bits (418), Expect = 9e-39 Identities = 118/355 (33%), Positives = 156/355 (43%), Gaps = 18/355 (5%) Query: 32 YIANGCLVDGPIGRVGLEIEAHCYDPADPHRR-----------PSWEEIGDVLEGLGKPP 80 ++A C GP +G+E+E +D DP R P D Sbjct: 22 HLARICFKTGPPRWLGVELEWTVHDVDDPARPVGASRLRAALGPHSPRTLDTTSPAQPLR 81 Query: 81 GGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTM 140 G +VTVEPGG VE+S ++A + A + A L + AGL L G D R Sbjct: 82 HGGSVTVEPGGQVEISSATHTSVVALVTATEAEIAQLTALLGRAGLVLGAGGIDAHRSPR 141 Query: 141 RINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTM 200 + RY+AM + F +QV LD G A R AHA+GP + Sbjct: 142 PVFETPRYRAMRRVFDRRGPAGRRMMYSTAG--LQVCLDCGETDQLADRWATAHAIGPPL 199 Query: 201 IAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGAS--ADDPATDWAHYALKAPVM 258 +A A + G +GW S R W +D R + A DP W Y L AP++ Sbjct: 200 VAAFATAGRHAGRPTGWVSARMAAWLAIDPARTRAVWTPEQGAADPIASWTAYVLDAPLL 259 Query: 259 LVHNPDAVAVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDS 318 V + V FADW+ G + R PT DLDYH++TLFPPVRPR +LE+RYLD+ Sbjct: 260 CVRDGPDWTAPVGVTFADWLAGAL---PRPPTVDDLDYHVSTLFPPVRPRGYLELRYLDA 316 Query: 319 LSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAAS 373 + W V + LL +P A V A W AAR GL D L A A+ Sbjct: 317 QPEGNWSVPVAVVAALLSEPAVTRAARSLVGAQAQRWIAAARHGLHDNALAATAA 371 >tr|C7QH01|C7QH01_CATAD Tax_Id=479433 SubName: Full=Glutamate--cysteine ligase GCS2;[Catenulispora acidiphila] Length = 366 Score = 159 bits (403), Expect = 5e-37 Identities = 118/328 (35%), Positives = 150/328 (45%), Gaps = 25/328 (7%) Query: 31 QYIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPGGSAVTVEPG 90 +YI+ C GP RVG+E+E D P P + P +T+EPG Sbjct: 14 EYISGICFKTGPPSRVGVELEWFPRDARHPEHLPDRSRVLRAFADAADLPLSGTLTMEPG 73 Query: 91 GAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMRINPGARYQA 150 G ELS P D + I RD +LR + A+AGL LV +G + P R+ RY A Sbjct: 74 GQWELSSAPADSVRELIAVTDRDLTLLRRSAAEAGLELVGMGREHGHPPSRLVDHPRYVA 133 Query: 151 MEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQ----SGWASRVRLAHALGPTMIAIAAN 206 ME FF IQVNLDAG + + R RLAH L P + A+ Sbjct: 134 MEHFF--DRDNGSGRVMMCSTASIQVNLDAGTEHDGPEDFRRRWRLAHRLSPVLTAVFC- 190 Query: 207 SPMLGGEFSGWRSTRQRVWGQMDDGR-CGPILGASADDPATDWAHYALKAPVMLVHNPDA 265 RS R VW +D GR P L + DP + +A YAL A +M V D Sbjct: 191 -----------RSDRPAVWAAIDPGRTVAPPL--DSPDPRSAYAQYALDAKLMCVQRADD 237 Query: 266 VAVT--HHVPFADWVDGRVLL--GDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSLSD 321 T + F +W+ L DR PT DL YHLTTLFPPVRPR LE+R LD+L Sbjct: 238 GPWTAPAGLTFREWIKTGALEPGEDRAPTLEDLTYHLTTLFPPVRPRGHLELRVLDALPG 297 Query: 322 VFWPAVVFTLVTLLDDPGAAELAFEAVQ 349 W + L D AAE A+ A++ Sbjct: 298 DLWRVPTALVTALFHDAQAAEDAWAALE 325 >tr|Q5YQ02|Q5YQ02_NOCFA Tax_Id=37329 (gshA)SubName: Full=Putative glutamylcysteine synthetase;[Nocardia farcinica] Length = 438 Score = 158 bits (400), Expect = 1e-36 Identities = 113/310 (36%), Positives = 143/310 (46%), Gaps = 21/310 (6%) Query: 80 PGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPT 139 PGGS +TVEPGG +ELS P + D VLR A A + + L AD R Sbjct: 93 PGGSRITVEPGGQIELSSAPYAEAAELCARLREDAIVLREMLAAAAIRPLALAADADRRA 152 Query: 140 MRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWA-SRVRLAHALGP 198 R+ RY+AMEQ F QV++DAG +R + +GP Sbjct: 153 KRLLRSPRYRAMEQSFAGIGPFGKLMMCNTAAT--QVSVDAGTDPAEVRARWTALYTMGP 210 Query: 199 TMIAIAANSPMLGGEFSG-WRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPV 257 ++A A SP L G G W S R R W ++D R P + AD P T +A +AL P+ Sbjct: 211 ALVAAFACSPALRGAPPGRWASQRMRTWLRLDTLRTRPPVADWAD-PITGYARWALDVPL 269 Query: 258 MLVHNPDAVAVTHHVP-----------FADWVDGRVLLGD---RRPTYADLDYHLTTLFP 303 + V + D P FADW+ G L D RRP ADL YHLTTLFP Sbjct: 270 LCVRSVDGTTTCAGDPGENWTAPPGATFADWMAGA--LDDEIGRRPDPADLAYHLTTLFP 327 Query: 304 PVRPRQWLEIRYLDSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGL 363 PVRP LE+RYLD+ W + T LL P A P+A +W AAR GL Sbjct: 328 PVRPSGHLEVRYLDAQPGEDWTVPIHTFDALLAHPAVVAEATALAAPLADQWSQAARCGL 387 Query: 364 GDPRLHAAAS 373 D + A+ Sbjct: 388 ADGVVRTVAA 397 >tr|A8M1F4|A8M1F4_SALAI Tax_Id=391037 SubName: Full=Glutamate--cysteine ligase GCS2;[Salinispora arenicola] Length = 411 Score = 158 bits (400), Expect = 1e-36 Identities = 116/356 (32%), Positives = 155/356 (43%), Gaps = 19/356 (5%) Query: 32 YIANGCLVDGPIGRVGLEIEAHCYDPADPHRR-----------PSWEEIGDVLEGLGKPP 80 ++A C GP +G E+E +D DP R P D+ Sbjct: 22 HLARICFKTGPPRWLGTELEWIVHDAVDPARPVGASRLRAALGPHSPRTLDITSPAQPLR 81 Query: 81 GGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTM 140 GS+VTVEPGG VE+S + A + A + A L + AGL L G D R Sbjct: 82 YGSSVTVEPGGQVEVSTATHTSVAALVAATKAEIAQLTALLGRAGLVLGAGGIDAHRSPR 141 Query: 141 RINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTM 200 + RY+AM + F +Q+ LD G A R AHA+GP + Sbjct: 142 PMFETPRYRAMRRVFDRRGPAGRRMMYSTAG--LQICLDVGEADQLADRWATAHAIGPPL 199 Query: 201 IAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGASADD--PATDWAHYALKAPVM 258 +A A + G +GW S R W +D R + DD P W Y L AP++ Sbjct: 200 LAAFATAGRHAGRPTGWVSARMAAWLAIDPARTRAVWTPEQDDTDPIASWTEYVLAAPLL 259 Query: 259 LVHNPDAVAVTHH-VPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLD 317 + + T V FADW+ G + + PT DLDYH++TLFPPVRPR +LE+RYLD Sbjct: 260 CLRGGGSDWTTPDGVTFADWLAGAL---PQPPTIDDLDYHVSTLFPPVRPRGYLELRYLD 316 Query: 318 SLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAAS 373 + W V + LL +P A V A W AAR GL D L A+ Sbjct: 317 AQPGESWSVPVAVVAALLSEPAITRAARSLVGAQAQRWIAAARHGLRDDGLAVTAA 372 >tr|C3JX20|C3JX20_RHOER Tax_Id=596309 SubName: Full=Glutamate--cysteine ligase family protein;[Rhodococcus erythropolis SK121] Length = 407 Score = 158 bits (399), Expect = 1e-36 Identities = 122/357 (34%), Positives = 152/357 (42%), Gaps = 24/357 (6%) Query: 32 YIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKP------------ 79 Y+ C GP VG E+E RPS + L G P Sbjct: 23 YVGGVCFKQGPPRLVGAELE-WLTSQVPGGERPSAATLAKAL-GRHAPTSIDPDSPAVPL 80 Query: 80 PGGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPT 139 P GS VTVEPGG +ELS P D + D+ L + A + + AD RP Sbjct: 81 PRGSLVTVEPGGQIELSSAPRTSARELCDCLDEDRRTLETLLASYSIEISSAAADVARPP 140 Query: 140 MRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPT 199 RI RY AME F + V+ P+S A R RL +GP Sbjct: 141 SRILRLPRYCAMESRFAGIGPYGTLMMCNTAAVQVSVDAGGSPES-IAQRWRLLGDMGPA 199 Query: 200 MIAIAANSPMLGGEFSG-WRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVM 258 +IA A SP L G G W S R R W ++D R A D+A +AL P+M Sbjct: 200 LIAAFACSPRLQGVPRGDWASQRMRTWLELDSWR------TVAVPEVQDYAGWALDVPLM 253 Query: 259 LVHNP-DAVAVTHHVPFADWVDGRVLLG-DRRPTYADLDYHLTTLFPPVRPRQWLEIRYL 316 V N D F DW+DG + RRP +ADLDYHL+TLFPPVR LE+RY+ Sbjct: 254 CVRNEGDDWTAPRGATFGDWIDGALDAEIGRRPVWADLDYHLSTLFPPVRAVGHLEVRYI 313 Query: 317 DSLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAAS 373 D+ W V + LL P A +A A W AA GL D L +AA+ Sbjct: 314 DAQPGDLWRVPVAAIDALLSGPAVMREASDAAASTAGRWRDAAEYGLDDVELRSAAT 370 >tr|C1A343|C1A343_RHOE4 Tax_Id=234621 (gshA)SubName: Full=Putative glutamate--cysteine ligase; EC=6.3.2.2;[Rhodococcus erythropolis] Length = 407 Score = 157 bits (396), Expect = 3e-36 Identities = 122/356 (34%), Positives = 153/356 (42%), Gaps = 22/356 (6%) Query: 32 YIANGCLVDGPIGRVGLEIE---AHCYDPADPHRRPSWEEIG-------DVLEGLGKPPG 81 Y+ C GP VG E+E +H P +G D P Sbjct: 23 YVGGVCFKQGPPRLVGAELEWLTSHVPGGERPSAATLARALGRHAPTSIDPDSPAAPLPR 82 Query: 82 GSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTMR 141 GS VTVEPGG +ELS P D + D+ L + A + + AD RP R Sbjct: 83 GSLVTVEPGGQIELSSAPRTSARELCDCLDDDRRTLETLLAPYSIEISSAAADVARPPSR 142 Query: 142 INPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQ-SGWASRVRLAHALGPTM 200 I RY AME F +Q+++DAG A R RL +GP + Sbjct: 143 ILRLPRYCAMESRFAGIGPYGTLMMCNTAA--VQISVDAGGSLESIAQRWRLLGDMGPAL 200 Query: 201 IAIAANSPMLGGEFSG-WRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVML 259 IA A SP L G G W S R R W ++D R A D+A +AL P+M Sbjct: 201 IAAFACSPRLQGVPKGDWASQRMRTWLELDSWR------TVAVPEVQDYAGWALDVPLMC 254 Query: 260 VHNP-DAVAVTHHVPFADWVDGRVLLG-DRRPTYADLDYHLTTLFPPVRPRQWLEIRYLD 317 V N D F DW+DG V RRP +ADLDYHL+TLFPPVR LE+RY+D Sbjct: 255 VRNEGDDWTAPRGATFGDWIDGAVDAEIGRRPVWADLDYHLSTLFPPVRAVGHLEVRYID 314 Query: 318 SLSDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAAS 373 + W V + LL P A +A A W AA GL D L +AA+ Sbjct: 315 AQPGDLWRVPVAAIDALLSGPAVMREASDAAASTAGRWRDAAEYGLDDVELRSAAT 370 >tr|C4RDQ5|C4RDQ5_9ACTO Tax_Id=219305 SubName: Full=Glutamate-cysteine ligase GCS2;[Micromonospora sp. ATCC 39149] Length = 537 Score = 149 bits (377), Expect = 5e-34 Identities = 108/303 (35%), Positives = 141/303 (46%), Gaps = 21/303 (6%) Query: 31 QYIANGCLVDGPIGRVGLEIEAHCYDPADPHRRPSWEEIGDVLEGLGKPPG--------- 81 ++IA C GP R G+E+E +D ADP R E + L G P Sbjct: 9 RHIARICFKTGPPTRTGVELEWTVHDAADPARPVDRERLRAAL-GPHSPTTIDDSSPAAP 67 Query: 82 ---GSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRP 138 GS VTVEPGG +E+S P + A I+A + D A + AGL L G DP R Sbjct: 68 LRHGSTVTVEPGGQIEISTAPRSSVAALIEATNADIAQVTDLLRRAGLLLGRTGIDPWRL 127 Query: 139 TMRINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGP 198 RY+AM F +QV LDAG + A+R HA+GP Sbjct: 128 PRPTVDTPRYRAMRCVFDRGGPAGRTMMYSTAG--LQVCLDAGEPAHVAARWAAVHAVGP 185 Query: 199 TMIAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGASADD--PATDWAHYALKAP 256 ++A A + G +GW S R W +D R P+ D P W YAL AP Sbjct: 186 PLLAAFATADRHAGRRTGWASARMAAWLAIDPARTRPVWSPQQPDADPVAAWTAYALAAP 245 Query: 257 VMLVHNPDAV-AVTHHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRY 315 ++ + + A V F DW+ G + R PT DL+YHL+TLFP VRPR +LEIRY Sbjct: 246 LLCLRDDTADWTPPPGVTFGDWIAGAL---PRPPTTDDLEYHLSTLFPVVRPRGYLEIRY 302 Query: 316 LDS 318 LD+ Sbjct: 303 LDT 305 >tr|C4DSG7|C4DSG7_9ACTO Tax_Id=446470 SubName: Full=Gamma-glutamylcysteine synthetase;[Stackebrandtia nassauensis DSM 44728] Length = 410 Score = 140 bits (353), Expect = 3e-31 Identities = 111/354 (31%), Positives = 152/354 (42%), Gaps = 22/354 (6%) Query: 32 YIANGCLVDGPIGRVGLEIEAHCY---DPADP----HRRPSWEEIGDVLEGLGKP----P 80 Y+A C GP G+E+E + DPA+P R + + P P Sbjct: 28 YVARVCFKTGPPALTGVELEHTVHRLDDPAEPVGLTELRTALGPFAPITIDPRSPSRRLP 87 Query: 81 GGSAVTVEPGGAVELSGPPCDGILAAIDAMHRDQAVLRSAFADAGLGLVCLGADPIRPTM 140 GG +VTVEPGG VE+S P G A ++ D L LG+ G DP Sbjct: 88 GGGSVTVEPGGQVEISSLPHSGFPALHASVETDLRALEDLLRVHRLGIGDSGFDPRSRPG 147 Query: 141 RINPGARYQAMEQFFXXXXXXXXXXXXXXXXXXIQVNLDAGPQSGWASRVRLAHALGPTM 200 R+ RY AM + F +QV +D+G + SR HA+GP + Sbjct: 148 RLLRTPRYDAMARAFDQHGTPHGSSMMVATAG-LQVCVDSGRDTELPSRWAALHAMGPVL 206 Query: 201 IAIAANSPMLGGEFSGWRSTRQRVWGQMDDGRCGPILGASADDPATDWAHYALKAPVMLV 260 +A+ + S R R W M+ GR + DP + W Y L+APV+ V Sbjct: 207 LALFSTSRRPDAA-----CVRMRTWLGMEPGRTHAV-ATDTGDPVSAWVDYVLRAPVLCV 260 Query: 261 HNPDAVAVT-HHVPFADWVDGRVLLGDRRPTYADLDYHLTTLFPPVRPRQWLEIRYLDSL 319 T V F W+ G + P+ DL+ HL+ LFPPVRPR +LE+RYLD+ Sbjct: 261 RRDGRPWFTPRDVSFEAWLGGAL---PDPPSLDDLELHLSMLFPPVRPRGYLEVRYLDTQ 317 Query: 320 SDVFWPAVVFTLVTLLDDPGAAELAFEAVQPVATEWDTAARAGLGDPRLHAAAS 373 W A V + LL + + + PV W AA GL DP L AA+ Sbjct: 318 PRRQWFAPVAVIGALLASASSIDKVRDLCAPVEGRWLDAATRGLADPDLRQAAA 371 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.321 0.138 0.443 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 3,169,693,361 Number of extensions: 131764174 Number of successful extensions: 265387 Number of sequences better than 10.0: 372 Number of HSP's gapped: 265911 Number of HSP's successfully gapped: 372 Length of query: 429 Length of database: 3,846,993,858 Length adjustment: 140 Effective length of query: 289 Effective length of database: 2,268,465,438 Effective search space: 655586511582 Effective search space used: 655586511582 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 82 (36.2 bits)