AL450380.2	Mycobrowser_v2	CDS	1101355	1101940	.	+	0	Locus=ML0932;Name=ML0932;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0932, len: 586 bp. Possible pseudogene of M. tuberculosis orthologue Rv1815 (666 bp) (Best blastx scores: 237).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1066281	1067327	.	-	0	Locus=ML0900c;Name=idsA2;Function=;Product=Probable geranylgeranyl pyrophosphate synthase IdsA2 (pseudogene);Comments=ML0900c, len: 1047 bp. Possible pseudogene of M. tuberculosis orthologue idsA2|Rv2173 (1059 bp) (Best blastx scores: 561).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1055789	1056223	.	+	0	Locus=ML0889;Name=ML0889;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN TB16.3 HOMOLOG ;Comments=ML0889, len: 144 aa. Conserved hypothetical protein.  Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2185c|O53519|AL021957 (144 aa), fasta scores: E(): 1.2e-50,(84.722% identity  in 144 aa overlap). Previously sequenced as Mycobacterium leprae hypothetical protein O53519|AL021957 (144 aa), Fasta scores: E(): 0, 84.7% identity in 144 aa overlap.;UniProt_AC=O69575;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1122422	1123023	.	-	0	Locus=ML0954c;Name=ML0954c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0954c, len: 602 bp. Possible pseudogene of M. tuberculosis orthologue Rv1126c (606 bp) (Best blastx scores: 364). Note the N-terminal region of this putative pseudogene was previously published O05567.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1079143	1080222	.	+	0	Locus=ML0911;Name=murX;Function=;Product=Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX;Comments=ML0911, len: 359 aa. Probable murX, phospho-N-acetylmuramoyl-pentappeptidetransferase (EC 2.7.8.13). Identical to the previously sequenced Mycobacterium leprae phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) SW:MRAY_MYCLE (SW:O69555) (359 aa), Fasta scores: E(): 0, 100.0% identity in 359 aa overlap(SW:O69555). Also highly similar to phospho-N-acetylmuramoyl-pentapeptide-transferases from Mycobacterium tuberculosis Rv2156c SW:MRAY_MYCTU (SW:O06221) (359 aa), Fasta scores: E(): 0, 91.1% identity in 359 aa overlap(SW:O06221) and Escherichia coli SW:MRAY_ECOLI (SW:P15876) (360 aa), Fasta scores: E(): 6.2e-29, 35.9% identity in 343 aa overlap(SW:P15876). Contains multiple possible membrane spanning hydrophobic domains and a possible N-terminal signal sequence. Contains Pfam match to entry PF00953 Glycos_transf_4, Glycosyl transferase.;UniProt_AC=O69555;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1080224	1081696	.	+	0	Locus=ML0912;Name=murD;Function=;Product=Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD;Comments=ML0912, len: 490 aa. Probable murD, UDP-N-acetylmuramoylalanine-D-glutamate ligase. Identical to the previously sequenced Mycobacterium leprae UDP-N-acetylmuramoylalanine-D-glutamate ligase TR:O69554 (EMBL:AL022602) (490 aa), Fasta scores: E(): 0, 99.8% identity in 490 aa overlap. Also highly similar to orthologues from Mycobacterium tuberculosis SW:MURD_MYCTU (SW:O06222) (486 aa), Fasta scores: E(): 0, 75.9% identity in 493 aa overlap and Bacillus subtilis SW:MURD_BACSU (SW:Q03522) (451 aa), Fasta scores: E(): 7.1e-24, 28.4% identity in 493 aa overlap. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family. Belongs to the murCDEF family. ;UniProt_AC=P57995;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1102571	1103269	.	+	0	Locus=ML0933;Name=ML0933;Function=;Product=Possible transcriptional regulatory protein (pseudogene);Comments=ML0933, len: 699 bp. Possible pseudogene of M. tuberculosis orthologue Rv1816 (705 bp) (Best blastx scores: 526).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1103997	1105282	.	+	0	Locus=ML0934;Name=ML0934;Function=;Product=Possible flavoprotein (pseudogene);Comments=ML0934, len: 1286 bp. Possible pseudogene of M. tuberculosis orthologue Rv1817 (1464 bp) (Best blastx scores: 395).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1110642	1110824	.	+	0	Locus=ML0940;Name=ML0940;Function=;Product=Possible exported protein (pseudogene);Comments=ML0940, len: 183 bp. Possible pseudogene of M. tuberculosis orthologue Rv1115 (699 bp) (Best blastx scores: 139).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1111225	1111513	.	+	0	Locus=ML0941;Name=ML0941;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0941, len: 289 bp. Possible pseudogene of M. tuberculosis orthologue Rv1117 (324 bp) (Best blastx scores: 151);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1112748	1114128	.	+	0	Locus=ML0943;Name=zwf1;Function=;Product=Probable glucose-6-phosphate 1-dehydrogenase Zwf1 (pseudogene);Comments=ML0943, len: 1381 bp. Possible pseudogene of M. tuberculosis orthologue zwf1|Rv1121 (1401 bp) (Best blastx scores: 420).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1114163	1115172	.	+	0	Locus=ML0944;Name=gnd2;Function=;Product=Probable 6-phosphogluconate dehydrogenase, decarboxylating Gnd2 (pseudogene);Comments=ML0944, len: 1010 bp. Possible pseudogene of M. tuberculosis orthologue gnd2|Rv1122 (1023 bp) (Best blastx scores: 395).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1118092	1118540	.	+	0	Locus=ML0948;Name=ML0948;Function=;Product=Hypothetical protein (pseudogene).;Comments=ML0948, len: 449 bp. Possible pseudogene of a protein of unknown function from Streptomyces coelicolor Q9X7R8|AL049863.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1119352	1120284	.	+	0	Locus=ML0951;Name=ephC;Function=;Product=Probable epoxide hydrolase EphC (pseudogene);Comments=ML0951, len: 933 bp. Possible pseudogene of M. tuberculosis orthologue ephC|Rv1124 (951 bp) (Best blastx scores: 389).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1120292	1121496	.	+	0	Locus=ML0952;Name=ML0952;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0952, len: 1205 bp. Possible pseudogene of M. tuberculosis orthologue Rv1125 (1245 bp) (Best blastx scores: 383).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1096067	1096435	.	-	0	Locus=ML0926c;Name=ML0926c;Function=;Product=hypothetical protein;Comments=ML0926c, len: 122 aa. Hypothetical unknown protein, weakly similar in parts to Y940_MYCTU|P71569|Rv0940c from Mycobacterium tuberculosis (288 aa), Fasta scores: E(): 0.0071, (30.4% identity in 112 aa overlap).;UniProt_AC=Q9CCD7;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1096527	1096835	.	-	0	Locus=ML0927c;Name=ML0927c;Function=;Product=hypothetical protein;Comments=ML0927c, len: 102 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCD6;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1098056	1098340	.	+	0	Locus=ML0928;Name=ML0928;Function=;Product=hypothetical protein;Comments=ML0928, len: 94 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCD5;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1109895	1110191	.	+	0	Locus=ML0938;Name=ML0938;Function=;Product=hypothetical protein;Comments=ML0938, len: 98 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCD4;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1110188	1110430	.	+	0	Locus=ML0939;Name=ML0939;Function=;Product=hypothetical protein;Comments=ML0939, len: 80 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCD3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1106315	1106413	.	-	0	Locus=ML0935c;Name=ML0935c;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML0935c, len: 99 bp. Possible transposase remnant, similar to Q44454|Z18270 transposase from Agrobacterium tumefaciens (366 aa), (blastx scores: 90); and to Q9R9U9|AJ245436 transposase tnpa1 from Pseudomonas putida (355 aa), (blastx scores: 86). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1127280	1127739	.	+	0	Locus=ML0960;Name=ML0960;Function=;Product=Conserved membrane protein (pseudogene);Comments=ML0960, len: 460 bp. Possible pseudogene of M. tuberculosis orthologue Rv1132 (1731 bp) (Best blastx scores: 183).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1130785	1131104	.	-	0	Locus=ML0962c;Name=ML0962c;Function=;Product=Possible transposase (pseudogene);Comments=ML0962c, len: 320 bp. Possible pseudogene similar to several M. tuberculosis IS1557 transposases e.g. Rv1313c, Rv3798 and Rv0741 (Best blastx scores: 152).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1133796	1134788	.	-	0	Locus=ML0965c;Name=ML0965c;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML0965c, len: 993 bp. Possible pseudogene of M. tuberculosis orthologue Rv1138c (1017 bp) (Best blastx scores: 217).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1134799	1135292	.	-	0	Locus=ML0966c;Name=ML0966c;Function=;Product=Conserved hypothetical membrane protein (pseudogene);Comments=ML0966c, len: 494 bp. Possible pseudogene of M. tuberculosis orthologue Rv1139c (501 bp) (Best blastx scores: 225).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1135313	1136334	.	-	0	Locus=ML0967c;Name=ML0967c;Function=;Product=Possible chalcone synthase (pseudogene);Comments=ML0967c, len: 1022 bp. Possible pseudogene similar to M. tuberculosis pks11|Rv1665 or pks10|Rv1660 (Best blastx scores: 288).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1136840	1137338	.	+	0	Locus=ML0968;Name=ML0968;Function=;Product=Probable integral membrane protein (pseudogene);Comments=ML0968, len: 499 bp. Possible pseudogene of M. tuberculosis orthologue Rv1140 (849 bp) (Best blastx scores: 297).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1137508	1138601	.	+	0	Locus=ML0969;Name=mcr;Function=;Product=Probable alpha-methylacyl-CoA racemase Mcr (pseudogene);Comments=ML0969, len: 1094 bp. Possible pseudogene of M. tuberculosis orthologue mcr|Rv1143 (1083 bp) (Best blastx scores: 1092);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1138627	1139421	.	+	0	Locus=ML0970;Name=ML0970;Function=;Product=Probable short-chain type dehydrogenase/reductase (pseudogene);Comments=ML0970, len: 795 bp. Possible pseudogene of M. tuberculosis orthologue Rv1144 (Best blastx scores: 282). Also similar to ML1746c a possible pseudogene similar to M. tuberculosis Rv1144.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1140056	1140909	.	+	0	Locus=ML0971;Name=mmpL13a;Function=;Product=Probable conserved transmembrane transport protein MmpL13a (pseudogene);Comments=ML0971, len: 854 bp. Possible pseudogene of M. tuberculosis orthologue Rv1145|mmpL13a (912 bp) (Best blastx scores: 305).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1140950	1141217	.	+	0	Locus=ML0972;Name=mmpL13b;Function=;Product=Probable conserved transmembrane transport protein MmpL13b (pseudogene);Comments=ML0972, len: 268 bp. Possible pseudogene of M. tuberculosis orthologue Rv1146|mmpL13b (1413 bp) (Best blastx scores: 131).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1141226	1141420	.	+	0	Locus=ML0973;Name=ML0973;Function=;Product=Conserved hypothetical protein (pseudogene).;Comments=ML0973, len: 195 bp. Possible pseudogene of M. tuberculosis orthologue Rv1147 (651 bp) (Best blastx scores: 202).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1142462	1143289	.	-	0	Locus=ML0974c;Name=ML0974c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0974c, len: 828 bp. Possible pseudogene of M. tuberculosis orthologue Rv2751 (891 bp) (Best blastx scores: 348).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1143310	1144162	.	-	0	Locus=ML0975c;Name=ML0975c;Function=;Product=Probable dehydrogenase (pseudogene);Comments=ML0975c, len: 853 bp. Possible pseudogene of M. tuberculosis orthologue Rv2750 (819 bp) (Best blastx scores: 216).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1144203	1144445	.	-	0	Locus=ML0976c;Name=ML0976c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0976c, len: 243 bp. Possible pseudogene of M. tuberculosis orthologue Rv2749 (315 bp) (Best blastx scores: 131).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1119158	1119358	.	-	0	Locus=ML0950c;Name=ML0950c;Function=;Product=hypothetical protein;Comments=ML0950c, len: 66 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCD0;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1125857	1126231	.	-	0	Locus=ML0957c;Name=ML0957c;Function=;Product=hypothetical protein;Comments=ML0957c, len: 124 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCC7;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1126242	1126673	.	+	0	Locus=ML0958;Name=ML0958;Function=;Product=putative membrane protein;Comments=ML0958, len: 143 aa. Possible membrane protein containing a membrane spanning hydrophobic domain.;UniProt_AC=Q9CCC6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1126915	1127268	.	+	0	Locus=ML0959;Name=ML0959;Function=;Product=hypothetical protein;Comments=ML0959, len: 117 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCC5;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1148471	1148754	.	+	0	Locus=ML0980;Name=ML0980;Function=;Product=Possible transcriptional regulatory protein (pseudogene).;Comments=ML0980, len: 284 bp. Possible pseudogene of M. tuberculosis orthologue Rv2745c (339 bp) (Best blastx scores: 74).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1148894	1149722	.	+	0	Locus=ML0981;Name=35kd_ag;Function=;Product=Conserved 35 kDa ala-rich protein (pseudogene);Comments=ML0981, len: 829 bp. Possible pseudogene of M. tuberculosis orthologue 35kd_ag|Rv2744c (813 bp) (Best blastx scores: 624).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1149757	1150605	.	+	0	Locus=ML0982;Name=ML0982;Function=;Product=Possible conserved transmembrane alanine rich protein (pseudogene);Comments=ML0982, len: 849 bp. Possible pseudogene of M. tuberculosis orthologue Rv2743c (813 bp) (Best blastx scores: 792).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1150703	1150913	.	+	0	Locus=ML0983;Name=ML0983;Function=;Product=Conserved hypothetical arginine rich protein (pseudogene);Comments=ML0983, len: 211 bp. Possible pseudogene of M. tuberculosis orthologue Rv2742c (834 bp) (Best blastx scores: 144).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1159849	1160082	.	-	0	Locus=ML0992c;Name=ML0992c;Function=;Product=Probable transmembrane serine-threonine protein kinase (pseudogene);Comments=ML0992c, len: 234 bp. Possible pseudogene similar to M. tuberculosis pknE|Rv1743 (Best blastx scores: 104) also similar to pknH|Rv1266c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1160769	1162378	.	+	0	Locus=ML0993;Name=ML0993;Function=;Product=Probable conserved integral membrane alanine, valine and leucine rich protein (pseudogene);Comments=ML0993, len: 1610 bp. Possible pseudogene of M. tuberculosis orthologue Rv2729c (906 bp) (Best blastx scores: 226).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1420022	1420336	.	-	0	Locus=ML1203c;Name=glbN;Function=;Product=Probable hemoglobin GlbN (pseudogene);Comments=ML1203c, len: 315 bp. Possible pseudogene of M. tuberculosis orthologue glbN|Rv1542c (411 bp) (Best blastx scores: 104).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1131803	1132060	.	+	0	Locus=ML0964;Name=ML0964;Function=;Product=hypothetical protein;Comments=ML0964, len: 85 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCC3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1147169	1147711	.	-	0	Locus=ML0978c;Name=ML0978c;Function=;Product=possible acetyltransferase;Comments=ML0978c, len: 180 aa. Possible acetyltransferase (EC 2.-.-.-). Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O05559 (EMBL:Z94723) (180 aa), Fasta scores: E(): 0, 100.0% identity in 180 aa overlap. Also similar to several acetyltransferases including: Escherichia coli amino-acid acetyltransferase (EC 2.3.1.1) SW:ARGA_ECOLI (P08205) (443 aa), Fasta scores: E(): 0.0013, 26.8% identity in 123 aa overlap and Streptomyces coelicolor putative acetyltransferase TR:Q9X8N2 (EMBL:AL049628) (169 aa), Fasta scores: E(): 0, 59.8% identity in 164 aa overlap. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2747 TR:O33289 (EMBL:AL008967) (174 aa), Fasta scores: E(): 0, 86.2% identity in 174 aa overlap . Contains Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family.;UniProt_AC=O05559;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1151027	1151476	.	-	0	Locus=ML0984c;Name=ML0984c;Function=;Product=conserved hypothetical protein.;Comments=ML0984c, len: 149 aa. Conserved hypothetical protein. Almost identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49850 (EMBL:U00019) (178 aa), Fasta scores: E(): 0, 100.0% identity in 149 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2740 TR:O33283 (EMBL:AL008967) (149 aa), Fasta scores: E(): 3e-28, 52.0% identity in 150 aa overlap.;UniProt_AC=Q9CCC2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1197134	1197556	.	+	0	Locus=ML1032;Name=ML1032;Function=;Product=Probable conserved integral membrane alanine and leucine rich protein (pseudogene);Comments=ML1032, len: 423 bp. Possible pseudogene of M. tuberculosis orthologue Rv2693c (672 bp) (Best blastx scores: 118).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1166933	1168054	.	+	0	Locus=ML0998;Name=fadE20;Function=;Product=Probable acyl-CoA dehydrogenase FadE20 (pseudogene);Comments=ML0998, len: 1122 bp. Possible pseudogene of M. tuberculosis orthologue fadE20|Rv2724c (1161 bp) (Best blastx scores: 404).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1168383	1168736	.	-	0	Locus=ML0999c;Name=ML0999c;Function=;Product=Possible transposase (pseudogene);Comments=ML0999c, len: 354 bp. Possible pseudogene similar to several M. tuberculosis IS6110 transposases e.g. Rv2355, Rv1369c, Rv3326, Rv3187 etc  (Best blastx scores: 128).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1178460	1179494	.	-	0	Locus=ML1008c;Name=ML1008c;Function=;Product=Probable hydrolase (pseudogene);Comments=ML1008c, len: 1035 bp. Possible pseudogene of M. tuberculosis orthologue Rv2715 (1026 bp) (Best blastx scores: 361).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1420622	1421599	.	+	0	Locus=ML1204;Name=ML1204;Function=;Product=Possible fatty acyl CoA reductase (pseudogene);Comments=ML1204, len: 978 bp. Possible pseudogene of M. tuberculosis orthologue Rv1543 (1026 bp) (Best blastx scores: 277).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1165273	1166739	.	+	0	Locus=ML0997;Name=hflX;Function=;Product=PROBABLE GTP-BINDING PROTEIN HFLX;Comments=ML0997, len: 488 aa. Probable hflX, GTP-binding protein (EC 3.1.5.-). Identical to the previously sequenced Mycobacterium leprae HflX protein TR:Q49843 (EMBL:U00019) (518 aa), Fasta scores: E(): 0, 100.0% identity in 488 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2725c TR:O33230 (EMBLZ98209:) (495 aa), Fasta scores: E(): 0, 84.5% identity in 485 aa overlap and Escherichia coli GTP-binding protein HflX, located within the hflA (high frequency of lysogenization) locus governing lysis and lysogeny of bacteriophage lambda, SW:HFLX_ECOLI (P25519) (426 aa), Fasta scores: E(): 0, 38.3% identity in 428 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CCC0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1162623	1163321	.	+	0	Locus=ML0994;Name=ML0994;Function=;Product=CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN;Comments=ML0994, len: 232 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49835 (EMBL:U00019) (232 aa), Fasta scores: E(): 0, 99.6% identity in 232 aa overlap. Also highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv2728c TR:O33233 (EMBL:Z98209) (231 aa), Fasta scores: E(): 0, 68.5% identity in 232 aa overlap and Streptomyces coelicolor TR:O69964 (EMBL:AL022268) (237 aa), Fasta scores: E(): 1.3e-13, 32.9% identity in 243 aa overlap.;UniProt_AC=Q49835;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1181551	1182971	.	-	0	Locus=ML1012c;Name=sthA;Function=;Product=Probable soluble pyridine nucleotide transhydrogenase SthA (pseudogene);Comments=ML1012c, len: 1421 bp. Possible pseudogene of M. tuberculosis orthologue Rv2713|sthA (1407 bp) (Best blastx scores: 507).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1187884	1188092	.	+	0	Locus=ML1019;Name=ML1019;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1019, len: 209 bp. Possible pseudogene of M. tuberculosis orthologue Rv2706c (258 bp) (Best blastx scores: 69).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2251594	2252083	.	+	0	Locus=ML1872;Name=ML1872;Function=;Product=Probable transcriptional regulatory protein (TetR/AcrR family) (pseudogene);Comments=ML1872, len: 490 bp. Possible pseudogene of M. tuberculosis orthologue Rv0691c (597 bp) (Best blastx scores: 122).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1177173	1177658	.	+	0	Locus=ML1006;Name=ML1006;Function=;Product=conserved hypothetical protein;Comments=ML1006, len: 161 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49838 (EMBL:U00019) (138 aa), Fasta scores: E(): 0, 100.0% identity in 138 aa overlap. Note this CDS is 23 aa longer than the previously published sequence due to the assignment of the translational start site. Also highly similar to a number of other proteins of unknown function e.g. Mycobacterium tuberculosis Rv2717c TR:O07216 (EMBL:Z96072) (164 aa), Fasta scores: E(): 0, 73.8% identity in 164 aa overlap.;UniProt_AC=Q9CCB8;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2431237	2431879	.	-	0	Locus=ML2040c;Name=ML2040c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2040c, len: 643 bp. Possible pseudogene of M. tuberculosis orthologue Rv1874 (687 bp) (Best blastx scores: 169).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1198010	1198485	.	+	0	Locus=ML1034;Name=ML1034;Function=;Product=Probable antibiotic-transport integral membrane leucine and valine rich protein ABC transporter (pseudogene);Comments=ML1034, len: 476 bp. Possible pseudogene of M. tuberculosis orthologue Rv2687c (714 bp) (Best blastx scores: 207).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1198513	1199223	.	+	0	Locus=ML1035;Name=ML1035;Function=;Product=Probable antibiotic-transport integral membrane leucine, alanine and valine rich protein ABC transporter (pseudogene);Comments=ML1035, len: 711 bp. Possible pseudogene of M. tuberculosis orthologue Rv2686c (759 bp) (Best blastx scores: 229).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1203552	1205229	.	+	0	Locus=ML1039;Name=ML1039;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML1039, len: 1678 bp. Possible pseudogene similar to M. tuberculosis Rv3727 (1809 bp) (Best blastx scores: 386).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1207292	1208090	.	-	0	Locus=ML1042c;Name=echA15;Function=;Product=Probable enoyl-CoA hydratase EchA15 (pseudogene);Comments=ML1042c, len: 799 bp. Possible pseudogene of M. tuberculosis orthologue echA15|Rv2679 (831 bp) (Best blastx scores: 306).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2252264	2252744	.	+	0	Locus=ML1873;Name=ML1873;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1873, len: 481 bp. Possible pseudogene of M. tuberculosis orthologue Rv0690c (1050 bp) (Best blastx scores: 169).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2286658	2287540	.	+	0	Locus=ML1902;Name=mmaA3;Function=;Product=Methoxy mycolic acid synthase 3 MmaA3 (pseudogene);Comments=ML1902, len: 883 bp. Possible pseudogene of M. tuberculosis orthologue mmaA3|Rv0643c (882 bp) (Best blastx scores: 295).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1194838	1195659	.	+	0	Locus=ML1029;Name=ML1029;Function=;Product=conserved hypothetical protein;Comments=ML1029, len: 273 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49993 (EMBL:U15181) (273 aa), Fasta scores: E(): 0, 99.6% identity in 273 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2696c TR:O07198 (EMBL:Z96072) (259 aa), Fasta scores: E(): 0, 70.6% identity in 262 aa overlap.;UniProt_AC=Q49993;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1195704	1196402	.	-	0	Locus=ML1030c;Name=ML1030c;Function=;Product=conserved hypothetical protein;Comments=ML1030c, len: 232 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49994 (EMBL:U15181) (232 aa), Fasta scores: E(): 0, 99.6% identity in 232 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2695 TR:O07197 (EMBL:Z96072) (235 aa), Fasta scores: E(): 0, 76.5% identity in 230 aa overlap.;UniProt_AC=Q49994;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1284316	1285506	.	+	0	Locus=ML1110;Name=ML1110;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1110, len: 1191 bp. Possible pseudogene of M. tuberculosis orthologue Rv0074 (1236 bp) (Best blastx scores: 257).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1791960	1792501	.	-	0	Locus=ML1487c;Name=ML1487c;Function=;Product=Probable conserved integral membrane alanine, valine and leucine rich protein (pseudogene);Comments=ML1487c, len: 542 bp. Possible pseudogene similar to M. tuberculosis Rv2690c (1974 bp) (Best blastx scores: 112).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1214210	1215451	.	-	0	Locus=ML1048c;Name=ML1048c;Function=;Product=Possible transposase (pseudogene);Comments=ML1048c, len: 1242 bp. Possible pseudogene similar to several M. tuberculosis transposases e.g. Rv2885c, Rv2791, Rv0606, Rv3827 and Rv2978 (Best blastx scores: 388).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1215475	1216057	.	-	0	Locus=ML1049c;Name=ML1049c;Function=;Product=Possible resolvase (pseudogene);Comments=ML1049c, len: 583 bp. Possible pseudogene similar to several M. tuberculosis possible resolvases e.g. Rv2886, Rv0605, Rv3828, Rv2979 and Rv2792 (Best blastx scores: 329).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1216313	1217035	.	+	0	Locus=ML1050;Name=ML1050;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1050, len: 723 bp. Possible pseudogene of M. tuberculosis orthologue Rv1191 (915 bp) (Best blastx scores: 177).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1220733	1221370	.	+	0	Locus=ML1054;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML1054, len: 638 bp. Possible pseudogene of M. tuberculosis PPE18|Rv1196 (1176 bp) (Best blastx scores: 821). Also similar to ML1182c a possible orthologue of M. tuberculosis Rv1196.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1224796	1226256	.	-	0	Locus=ML1060c;Name=ML1060c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1060c, len: 1461 bp. Possible pseudogene of M. tuberculosis orthologue Rv1204c (1689 bp) (Best blastx scores: 256).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1227059	1228576	.	+	0	Locus=ML1062;Name=fadD6;Function=;Product=Probable fatty-acid-CoA ligase ligase FadD6 (pseudogene);Comments=ML1062, len: 1518 bp. Possible pseudogene of M. tuberculosis orthologue fadD6|Rv1206 (1794 bp) (Best blastx scores: 281).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1236833	1237671	.	-	0	Locus=ML1073c;Name=ML1073c;Function=;Product=Probable tetronasin-transport ATP-binding protein ABC transporter (pseudogene);Comments=ML1073c, len: 839 bp. Possible pseudogene of M. tuberculosis orthologue Rv1218c (936 bp) (Best blastx scores: 278).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1237771	1238312	.	-	0	Locus=ML1074c;Name=ML1074c;Function=;Product=Probable transcriptional regulatory protein (pseudogene);Comments=ML1074c, len: 542 bp. Possible pseudogene of M. tuberculosis orthologue Rv1219c (639 bp) (Best blastx scores: 232).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1221436	1221738	.	+	0	Locus=ML1055;Name=esxK1;Function=;Product=ESAT-6 LIKE PROTEIN ESXK1 (ESAT-6 LIKE PROTEIN 3);Comments=ML1055, len: 100 aa. Probable esxK1, esat-6 like protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49945 (EMBL:U15180) (100 aa), Fasta scores: E(): 0, 100.0% identity in 100 aa overlap. Also similar to several proteins of undefined function from Mycobacterium tuberculosis e.g. TR:O05299 (EMBL:Z93777) (98 aa), Fasta scores: E(): 1.7e-20, 58.3% identity in 96 aa overlap. Identical to ML1181c a possible paralogue of M. tuberculosis esxK.;UniProt_AC=Q49945;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1245009	1245563	.	-	0	Locus=ML1081c;Name=ML1081c;Function=;Product=Possible membrane protein (pseudogene);Comments=ML1081c, len: 555 bp. Possible pseudogene of M. tuberculosis orthologue Rv1230c (1236 bp) (Best blastx scores: 149).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1246854	1247468	.	-	0	Locus=ML1084c;Name=ML1084c;Function=;Product=Conserved hypothetical membrane protein (pseudogene);Comments=ML1084c, len: 615 bp. Possible pseudogene of M. tuberculosis orthologue Rv1233c (597 bp) (Best blastx scores: 522).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1247772	1248299	.	+	0	Locus=ML1085;Name=ML1085;Function=;Product=Probable transmembrane protein (pseudogene);Comments=ML1085, len: 528 bp. Possible pseudogene of M. tuberculosis orthologue Rv1234 (528 bp) (Best blastx scores: 132).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1238389	1239063	.	-	0	Locus=ML1075c;Name=ML1075c;Function=;Product=PROBABLE METHYLTRANSFERASE;Comments=ML1075c, len: 224 aa. Probable methyltransferase (EC 2.1.1.-). Previously sequenced Mycobacterium leprae TR:Q49969 (EMBL:U15180) (136 aa), Fasta scores: E(): 0, 100.0% identity in 136 aa overlap. Also highly similar to Mycobacterium tuberculosis possible methyltransferase Rv1220c TR:O33219 (EMBL:Z98260) (215 aa), Fasta scores: E(): 0, 85.5% identity in 214 aa overlap and Streptomyces mycarofaciens O-methyltransferase (EC 2.1.1.-) involved in the synthesis of the macrolide antibiotic midecamycin SW:MDMC_STRMY (Q00719) (221 aa), Fasta scores: E(): 2.3e-11, 30.5% identity in 223 aa overlap. Contains Pfam match to entry PF01596 Methyltransf_3, O-methyltransferase.;UniProt_AC=Q9CCA7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1265107	1266380	.	+	0	Locus=ML1097;Name=ML1097;Function=;Product=Probable drug-transport integral membrane protein (pseudogene);Comments=ML1097, len: 1274 bp. Possible pseudogene of M. tuberculosis orthologue Rv1250 (1740 bp) (Best blastx scores: 225).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1271266	1272635	.	+	0	Locus=ML1100;Name=deaD;Function=;Product=Probable cold-shock DEAD-box protein A homolog DeaD (pseudogene);Comments=ML1100, len: 1370 bp. Possible pseudogene of M. tuberculosis orthologue deaD|Rv1253 (1692 bp) (Best blastx scores: 769).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1275357	1276453	.	-	0	Locus=ML1102c;Name=cyp130;Function=;Product=Probable cytochrome P450 Cyp130 (pseudogene);Comments=ML1102c, len: 1097 bp. Possible pseudogene of M. tuberculosis orthologue cyp130|Rv1256c (1218 bp) (Best blastx scores: 356).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1277827	1278922	.	-	0	Locus=ML1104c;Name=ML1104c;Function=;Product=Probable conserved integral membrane transport protein (pseudogene);Comments=ML1104c, len: 1096 bp. Possible pseudogene of M. tuberculosis orthologue Rv1258c (1260 bp) (Best blastx scores: 234).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1280741	1281177	.	-	0	Locus=ML1107c;Name=ML1107c;Function=;Product=Hypothetical HIT-like protein (pseudogene);Comments=ML1107c, len: 437 bp. Possible pseudogene of M. tuberculosis orthologue Rv1262c (435 bp) (Best blastx scores: 270).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1282284	1283494	.	+	0	Locus=ML1109;Name=amiB2;Function=;Product=Probable amidase AmiB2 (pseudogene);Comments=ML1109, len: 1211 bp. Possible pseudogene of M. tuberculosis orthologue amiB2|Rv1263 (1389 bp) (Best blastx scores: 454).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2298478	2298822	.	+	0	Locus=ML1915;Name=ML1915;Function=;Product=hypothetical protein;Comments=ML1915, len: 114 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBJ3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1257732	1258589	.	+	0	Locus=ML1093;Name=lpqZ;Function=;Product=PROBABLE LIPOPROTEIN LPQZ;Comments=ML1093, len: 285 aa. Probable lpqZ lipoprotein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49982 (EMBL:U15180) (227 aa), Fasta scores: E(): 0, 100.0% identity in 227 aa overlap. Also highly similar to Mycobacterium tuberculosis lipoprotein Rv1244, TR:O50459 (EMBL:AL021006) (286 aa), Fasta scores: E(): 0, 73.5% identity in 287 aa overlap and weakly similar to several others e.g. Streptomyces coelicolor TR:Q9X832 (EMBL:AL049727) (320 aa), Fasta scores: E(): 2.9, 26.1% identity in 299 aa overlap putative secreted substrate-binding protein. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CC99;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1294766	1295917	.	+	0	Locus=ML1119;Name=ML1119;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML1119, len: 383 aa. Conserved hypothetical protein. Highly similar but shorter to Mycobacterium tuberculosis hypothetical protein Rv1277 TR:Q50699 (EMBL:Z77137) (417 aa), Fasta scores: E(): 0, 82.0% identity in 383 aa overlap.;UniProt_AC=Q9CC84;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1303219	1304118	.	-	0	Locus=ML1123c;Name=oppC;Function=;Product=PROBABLE OLIGOPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER OPPC;Comments=ML1123c, len: 299 aa. Probable oppC, oligopeptide-transport integral membrane protein ABC transporter. Highly similar to many membrane transport proteins e.g. Mycobacterium tuberculosis putative peptide transport permease Rv1282c SW:YC82_MYCTU (Q10623) (291 aa), Fasta scores: E(): 0, 82.6% identity in 287 aa overlap and Escherichia coli SW:OPPC_ECOLI (P77664) (302 aa), Fasta scores: E(): 0, 38.8% identity in 289 aa overlap oligopeptide transport system permease protein. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.;UniProt_AC=Q9CC80;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1610687	1611373	.	-	0	Locus=ML1350c;Name=ML1350c;Function=;Product=Probable conserved ATP-binding protein ABC transporter (pseudogene);Comments=ML1350c, len: 687 bp. Possible pseudogene of M. tuberculosis orthologue Rv1687c (768 bp) (Best blastx scores: 515).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1387518	1388409	.	-	0	Locus=ML1187c;Name=ML1187c;Function=;Product=Probable fatty-acid-CoA ligase (pseudogene);Comments=ML1187c, len: 892 bp. Possible pseudogene similar to several M. tuberculosis  fatty-acid-CoA synthetases e.g. fadD4|Rv0214, fadD8|Rv0551c, fadD12|Rv1427c etc (Best blastx scores: 98).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1408810	1410075	.	-	0	Locus=ML1194c;Name=ML1194c;Function=;Product=Probable conserved polyketide synthase associated protein (pseudogene);Comments=ML1194c, len: 1266 bp. Possible pseudogene similar to several M. tuberculosis probable polyketide synthases e.g. papA1|Rv3824c, papA3|Rv1182 and papA2|Rv3820c (Best blastx scores: 212).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1323334	1325166	.	+	0	Locus=ML1132;Name=rho;Function=;Product=PROBABLE TRANSCRIPTION TERMINATION FACTOR RHO HOMOLOG;Comments=ML1132, len: 610 aa. Probable transcription termination factor rho homolog. Identical to the previously sequenced Mycobacterium leprae transcription termination factor Rho SW:RHO_MYCLE (P45835) (610 aa), Fasta scores: E(): 0, 99.8% identity in 610 aa overlap. Also highly similar to many other transcriptional terminators including: Mycobacterium tuberculosis Rv1297 SW:RHO_MYCTU (Q10607) (602 aa), Fasta scores: E(): 0, 81.5% identity in 616 aa overlap and Micrococcus luteus SW:RHO_MICLU (P52154) (690 aa), Fasta scores: E(): 0, 66.0% identity in 467 aa overlap. Contains Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family.;UniProt_AC=P45835;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	rRNA	1342979	1346103	.	+	0	Locus=MLP000017;Name=rrl;Function=;Product=;Comments=23S ribosomal RNA gene as assigned by Liesack W.C et al., (1991) FEBS Lett. 281:114-118;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	1814658	1814990	.	-	0	Locus=ML1503c;Name=mutT2;Function=;Product=Probable mutator protein MutT (pseudogene);Comments=ML1503c, len: 333 bp. Possible pseudogene of M. tuberculosis orthologue mutT2|Rv1160 (426 bp) (Best blastx scores: 187).;UniProt_AC=Q9CBX1;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1438004	1438257	.	-	0	Locus=ML1215c;Name=ML1215c;Function=;Product=Probable hypothetical membrane protein (pseudogene);Comments=ML1215c, len: 254 bp. Possible pseudogene of M. tuberculosis orthologue Rv1567c (285 bp) (Best blastx scores: 76).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1432450	1434638	.	-	0	Locus=ML1212c;Name=treX;Function=;Product=Probable maltooligosyltrehalose synthase TreX (pseudogene);Comments=ML1212c, len: 2189 bp. Possible pseudogene of M. tuberculosis orthologue treX|Rv1564c (2166 bp) (Best blastx scores: 387).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1329965	1330426	.	+	0	Locus=ML1138;Name=ML1138;Function=;Product=possible integral membrane protein;Comments=ML1138, len: 153 aa. Possible integral membrane protein. Identical to the previously sequenced Mycobacterium leprae SW:YD03_MYCLE (P53431) (153 aa), Fasta scores: E(): 0, 99.3% identity in 153 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1303 SW:YD03_MYCTU (Q10619) (161 aa), Fasta scores: E(): 0, 69.8% identity in 149 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=P53431;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1355244	1357421	.	-	0	Locus=ML1160c;Name=glgB;Function=;Product=Probable 1,4-[alpha]-glucan branching enzyme GlgB (pseudogene);Comments=ML1160c, len: 2178 bp. Possible pseudogene of M. tuberculosis orthologue glgB|Rv1326c (2196 bp) (Best blastx scores: 959).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1357447	1359543	.	-	0	Locus=ML1161c;Name=glgE;Function=;Product=Probable glucanase GlgE (pseudogene);Comments=ML1161c, len: 2097 bp. Possible pseudogene of M. tuberculosis orthologue Rv1327c|glgE (2106 bp) (Best blastx scores: 650).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1360095	1362293	.	+	0	Locus=ML1162;Name=glgP;Function=;Product=Probable glycogen phosphorylase GlgP (pseudogene);Comments=ML1162, len: 2199 bp. Possible pseudogene of M. tuberculosis orthologue glgP|Rv1328 (2592 bp) (Best blastx scores: 579).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1363264	1364088	.	-	0	Locus=ML1163c;Name=ML1163c;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML1163c, len: 825 bp. Possible pseudogene similar to M. tuberculosis membrane proteins e.g. Rv3239c and Rv3728 (Best blastx scores: 223).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1364069	1364509	.	-	0	Locus=ML1164c;Name=ML1164c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1164c, len: 441 bp. Possible pseudogene of M. tuberculosis orthologue Rv1330c (1347 bp) (Best blastx scores: 280).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1367414	1368400	.	+	0	Locus=ML1170;Name=cysM;Function=;Product=Probable cysteine synthase B CysM (pseudogene);Comments=ML1170, len: 987 bp. Possible pseudogene of M. tuberculosis orthologue cysM|Rv1336 (Rv1336) (Best blastx scores: 302).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1351362	1352024	.	+	0	Locus=ML1155;Name=ML1155;Function=;Product=conserved hypothetical protein;Comments=ML1155, len: 220 aa. Conserved hypothetical protein. Previously sequenced Mycobacterium leprae hypothetical protein SW:YD21_MYCLE (P53524) (201 aa), Fasta scores: E(): 0, 99.5% identity in 193 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1321 SW:YD21_MYCTU (Q10634) (226 aa), Fasta scores: E(): 0, 88.2% identity in 220 aa overlap. Contains Pfam match to entry PF01939 DUF91, Protein of unknown function.;UniProt_AC=P53524;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1364615	1364941	.	+	0	Locus=ML1165;Name=ML1165;Function=;Product=conserved hypothetical protein;Comments=ML1165, len: 108 aa. Conserved hypothetical protein. Previously sequenced Mycobacterium leprae hypothetical protein SW:YD31_MYCLE (P53423) (94 aa), Fasta scores: E(): 0, 98.9% identity in 94 aa overlap. Also highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv1331 SW:YD31_MYCTU (Q10642) (101 aa), Fasta scores: E(): 0, 84.2% identity in 101 aa overlap and Streptomyces coelicolor TR:Q9S2G5 (EMBL:AL096852) (105 aa), Fasta scores: E(): 1.4e-20, 56.7% identity in 104 aa overlap.;UniProt_AC=P53423;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1868327	1870347	.	+	0	Locus=ML1545;Name=malQ;Function=;Product=Probable 4-alpha-glucanotransferase MalQ (pseudogene);Comments=ML1545, len: 2021 bp. Possible pseudogene of M. tuberculosis orthologue Rv1781c|malQ (2175 bp) (Best blastx scores: 285).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2264715	2265475	.	-	0	Locus=ML1886c;Name=ML1886c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1886c, len: 761 bp. Possible pseudogene of M. tuberculosis orthologue Rv0674 (723 bp) (Best blastx scores: 207).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1368495	1369211	.	+	0	Locus=ML1171;Name=ML1171;Function=;Product=PROBABLE INTEGRAL MEMBRANE PROTEIN;Comments=ML1171, len: 238 aa. Probable conserved integral membrane protein. Previously sequenced Mycobacterium leprae hypothetical protein SW:YD37_MYCLE (P53426) (251 aa), Fasta scores: E(): 0, 100.0% identity in 238 aa overlap. Also highly similar to other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1337 SW:YD37_MYCTU (Q10647) (240 aa), Fasta scores: E(): 0, 73.2% identity in 231 aa overlap. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01694 Rhomboid, Rhomboid family.;UniProt_AC=P53426;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1414681	1416057	.	+	0	Locus=ML1197;Name=dinX;Function=;Product=Probable DNA polymerase IV DinX (pseudogene);Comments=ML1197, len: 1377 bp. Possible pseudogene of M. tuberculosis orthologue dinX|Rv1537 (1392 bp) (Best blastx scores: 489).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1418702	1419340	.	-	0	Locus=ML1201c;Name=ML1201c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1201c, len: 639 bp. Possible pseudogene similar to M. tuberculosis Rv1597 (759 bp) (Best blastx scores: 186).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1419487	1419931	.	-	0	Locus=ML1202c;Name=lprI;Function=;Product=Possible lipoprotein LprI (pseudogene);Comments=ML1202c, len: 445 bp. Possible pseudogene of M. tuberculosis orthologue lprI|Rv1541c  (594 bp) (Best blastx scores: 128).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1386779	1387081	.	-	0	Locus=ML1186c;Name=ML1186c;Function=;Product=hypothetical protein;Comments=ML1186c, len: 100 aa. Hypothetical unknown protein.;UniProt_AC=Q9CC71;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1392496	1392879	.	-	0	Locus=ML1189c;Name=ML1189c;Function=;Product=hypothetical protein;Comments=ML1189c, len: 127 aa. Hypothetical unknown protein, identical to the previously sequenced Q9X7D8 Mycobacterium leprae hypothetical protein (127 aa).;UniProt_AC=Q9X7D8;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1390598	1390858	.	-	0	Locus=ML1188c;Name=ML1188c;Function=;Product=hypothetical protein;Comments=ML1188c, len: 86 aa. Hypothetical unknown protein. Similar in part to several putative GntR-family transcriptional regulators e.g. Q88DT5 Transcriptional regulator, GntR family from Pseudomonas putida (255 aa), fasta scores: E(): 0.061, (36.047% identity in 86 aa overlap).;UniProt_AC=Q9CC70;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1441748	1442260	.	+	0	Locus=ML1219;Name=ML1219;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1219, len: 513 bp. Possible pseudogene of M. tuberculosis orthologue Rv1571 (510 bp) (Best blastx scores: 374).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1875366	1875882	.	-	0	Locus=ML1551c;Name=ML1551c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1551c, len: 517 bp. Possible pseudogene of M. tuberculosis orthologue Rv2825c (648 bp) or Rv2828c (546 bp) (Best blastx scores: 313).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1444492	1445668	.	-	0	Locus=ML1223c;Name=ML1223c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1223c, len: 1177 bp. Possible pseudogene of M. tuberculosis orthologue Rv1592c (1341 bp) (Best blastx scores: 313).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1453268	1454046	.	+	0	Locus=ML1228;Name=ML1228;Function=;Product=Probable esterase (pseudogene);Comments=ML1228, len: 779 bp. Possible pseudogene similar to several M. tuberculosis esterases e.g. lipO|Rv1426c, lipM|Rv2284 and lipQ|Rv2485c etc (Best blastx scores: 158).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2994502	2995069	.	-	0	Locus=ML2514c;Name=ML2514c;Function=;Product=Probable integral membrane protein (pseudogene);Comments=ML2514c, len: 568 bp. Possible pseudogene similar to M. tuberculosis Rv3481c (690 bp) (Best blastx scores: 152);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1437013	1437651	.	-	0	Locus=ML1214c;Name=ML1214c;Function=;Product=Possible invasion protein (NLP/P60 family protein);Comments=ML1214c, len: 212 aa. Possible inv protein, probably exported as has QQAPV repeats at C-terminus. Previously sequenced Mycobacterium leprae TR:Q49634 (EMBL:U00010) (246 aa), Fasta scores: E(): 0, 100.0% identity in 206 aa overlap. This predicted product of this CDS is similar to several including a portion of Listeria monocytogenes SW:P60_LISMO (P21171) (484 aa), Fasta scores: E(): 0.0013, 29.7% identity in 148 aa overlap invasion-associated protein P60 and several other proteins of undefined function e.g. Mycobacterium tuberculosis Rv1566c TR:O06624 (EMBL:Z95586) (230 aa), Fasta scores: E(): 0, 69.4% identity in 209 aa overlap. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00877 NLPC_P60, NLP/P60 family.;UniProt_AC=Q9CC67;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1475276	1475717	.	-	0	Locus=ML1239c;Name=ML1239c;Function=;Product=Probable second part of macrolide-transport ATP-binding protein ABC transporter (pseudogene);Comments=ML1239c, len: 442 bp. Possible pseudogene of M. tuberculosis orthologue Rv1667c (654 bp) (Best blastx scores: 184).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1475429	1476053	.	-	0	Locus=ML1240c;Name=ML1240c;Function=;Product=Probable first part of macrolide-transport ATP-binding protein ABC transporter (pseudogene);Comments=ML1240c, len: 625 bp. Possible pseudogene of M. tuberculosis orthologue Rv1668c (1119 bp) (Best blastx scores: 93).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1478296	1480178	.	+	0	Locus=ML1242;Name=ML1242;Function=;Product=Probable transcriptional regulatory protein (LuxR/UhpA family) (pseudogene);Comments=ML1242, len: 1883 bp. Possible pseudogene similar to M. tuberculosis Rv0386 (3258 bp) (Best blastx scores: 259).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1480632	1480794	.	+	0	Locus=ML1242A;Name=ML1242A;Function=;Product=Probable transposase (pseudogene);Comments=ML1242A, len: 163 bp. Possible pseudogene similar to several M. tuberculosis transposases associated with IS6110 (Best blastx scores: 75) and identical to ML1291c, ML0599A, ML1820A, ML0568B from M. leprae.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1482136	1482597	.	+	0	Locus=ML1243;Name=lipQ;Function=;Product=PROBABLE CARBOXYLESTERASE LIPQ (PSEUDOGENE);Comments=ML1243, len: 153 aa.  Possible pseudogene similar to M. tuberculosis Rv2485c (Best blastx score 118).;UniProt_AC=Q9CC60;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1488722	1489018	.	+	0	Locus=ML1247;Name=ML1247;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1247, len: 297 bp. Possible pseudogene of M. tuberculosis orthologue Rv2478c (486 bp) (Best blastx scores: 155).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1495767	1496158	.	+	0	Locus=ML1250;Name=ML1250;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1250, len: 392 bp. Possible pseudogene of M. tuberculosis orthologue Rv2475c (417 bp) (Best blastx scores: 137).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1496183	1496718	.	+	0	Locus=ML1251;Name=ML1251;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1251, len: 536 bp. Possible pseudogene of M. tuberculosis orthologue Rv2474c (654 bp) (Best blastx scores: 207).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1496788	1498136	.	-	0	Locus=ML1252c;Name=aglA;Function=;Product=Probable maltase [alpha]-glucosidase AglA (pseudogene);Comments=ML1252c, len: 1349 bp. Possible pseudogene of M. tuberculosis orthologue Rv2471|aglA (1641 bp) (Best blastx scores: 408).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1501773	1502186	.	-	0	Locus=ML1256c;Name=ML1256c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1256c, len: 414 bp. Possible pseudogene of M. tuberculosis orthologue Rv1598c (411 bp) (Best blastx scores: 161).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2856452	2856783	.	+	0	Locus=ML2386;Name=ML2386;Function=;Product=Probable transmembrane protein (pseudogene);Comments=ML2386, len: 332 bp. Possible pseudogene of M. tuberculosis orthologue Rv0461 (525 bp) (Best blastx scores: 118).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1482820	1484295	.	+	0	Locus=ML1244;Name=ML1244;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML1244, len: 491 aa. Conserved hypothetical protein. Highly similar to a family of Mycobacterium tuberculosis proteins e.g. Rv2484c SW:YO84_MYCTU (O53209) (491 aa), Fasta scores: E(): 0, 75.2% identity in 483 aa overlap. ;UniProt_AC=Q9X7A8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1508362	1508709	.	+	0	Locus=ML1264;Name=hisI;Function=;Product=Probable phosphoribosyl-AMP 1,6 cyclohydrolase HisI;Comments=ML1264, len: 115 aa. Probable hisI, phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19). Highly similar to many phosphoribosyl-AMP cyclohydrolases involved in histidine biosynthesis including: Mycobacterium tuberculosis Rv1606 SW:HIS3_MYCTU (O53909) (115 aa), Fasta scores: E(): 0, 84.3% identity in 115 aa overlap and Bacillus subtilis SW:HIS2_BACSU (O34912) (209 aa), Fasta scores: E(): 6.3e-18, 50.0% identity in 98 aa overlap. Contains Pfam match to entry PF01502 PRA-CH, Phosphoribosyl-AMP cyclohydrolase.;UniProt_AC=Q9X7C3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2886194	2886538	.	+	0	Locus=ML2415;Name=ML2415;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2415, len: 345 bp. Possible pseudogene of M. tuberculosis orthologue Rv0523c (396 bp) (Best blastx scores: 205).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1499771	1500262	.	+	0	Locus=ML1255;Name=ML1255;Function=;Product=conserved hypothetical protein;Comments=ML1255, len: 163 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2468c TR:O53195 (EMBL:AL021246) (167 aa), Fasta scores: E(): 0, 81.2% identity in 165 aa overlap.;UniProt_AC=Q9CC58;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1679218	1680192	.	+	0	Locus=ML1399;Name=ML1399;Function=;Product=conserved hypothetical protein;Comments=ML1399, len: 324 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1647 TR:P94982 (EMBL:Z85982) (316 aa), Fasta scores: E(): 0, 74.0% identity in 312 aa overlap.;UniProt_AC=Q9CC18;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1498709	1499356	.	+	0	Locus=ML1254;Name=ML1254;Function=;Product=conserved hypothetical protein;Comments=ML1254, len: 215 aa. Conserved hypothetical protein. Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis Rv2469c TR:O53196 (EMBL:AL021246) (222 aa), Fasta scores: E(): 0, 77.9% identity in 222 aa overlap and Streptomyces coelicolor TR:CAB71830 (EMBL:AL138662) (178 aa), Fasta scores: E(): 0, 52.8% identity in 161 aa overlap. Contains Pfam match to entry PF01844 HNH, HNH endonuclease.;UniProt_AC=Q9X7B4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1526116	1527672	.	-	0	Locus=ML1282c;Name=cydD;Function=;Product=Probable 'component linked with the assembly of cytochrome' transmembrane ATP-binding protein ABC transporter CydD (pseudogene);Comments=ML1282c, len: 1557 bp. Possible pseudogene of M. tuberculosis orthologue Rv1621c|cydD (1584 bp) (Best blastx scores: 679).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1560503	1561560	.	-	0	Locus=ML1308c;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML1308c, len: 1058 bp. Possible pseudogene of M. tuberculosis orthologue PPE37|Rv2123 (1422 bp) (Best blastx scores: 241).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1571682	1572943	.	+	0	Locus=ML1319;Name=ML1319;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML1319, len: 1262 bp. Possible pseudogene similar to M. tuberculosis Rv3727 (1809 bp) (Best blastx scores: 380).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1776100	1776708	.	-	0	Locus=ML1474c;Name=mobA;Function=;Product=Probable molybdopterin-guanine dinucleotide biosynthesis protein A MobA (pseudogene);Comments=ML1474c, len: 609 bp. Possible pseudogene of M. tuberculosis orthologue Rv2453c|mobA (606 bp) (Best blastx scores: 269).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1807556	1808257	.	-	0	Locus=ML1499c;Name=narI;Function=;Product=Probable respiratory nitrate reductase (gamma chain) NarI (pseudogene);Comments=ML1499c, len: 702 bp. Possible pseudogene of M. tuberculosis orthologue narI|Rv1164 (741 bp) (Best blastx scores: 222).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1818586	1819133	.	-	0	Locus=ML1507c;Name=ML1507c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1507c, len: 548 bp. Possible pseudogene of M. tuberculosis orthologue Rv1156 (588 bp) (Best blastx scores: 351).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1819949	1820612	.	+	0	Locus=ML1509;Name=ML1509;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1509, len: 664 bp. Possible pseudogene of M. tuberculosis orthologue Rv1154c (642 bp) (Best blastx scores: 204).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1521269	1522162	.	+	0	Locus=ML1278;Name=tesB;Function=;Product=Probable acyl-CoA thioesterase II TesB;Comments=ML1278, len: 297 aa. Probable acyl-CoA thioesterase II (EC 3.1.2.-). Highly similar to many acyl CoA thioesterases including: Escherichia coli SW:TESB_ECOLI (P23911) (285 aa), Fasta scores: E(): 5.6e-26, 32.1% identity in 287 aa overlap and Mycobacterium tuberculosis Rv1618 TR:O06135 (EMBL:Z95554) (300 aa), Fasta scores: E(): 0, 85.1% identity in 288 aa overlap.;UniProt_AC=Q9CC48;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1828949	1829973	.	-	0	Locus=ML1515c;Name=hsdS;Function=;Product=Possible type I restriction/modification system specificity determinant HsdS (pseudogene);Comments=ML1515c, len: 1025 bp. Possible pseudogene of M. tuberculosis orthologue Rv2761c|hsdS (1095 bp) (Best blastx scores: 328).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1716928	1717254	.	+	0	Locus=ML1430;Name=ML1430;Function=;Product=Possible integral membrane protein;Comments=ML1430, len: 108 aa. Possible integral membrane protein. Similar to Q9KZZ3|AL353815 Putative integral membrane protein from Streptomyces coelicolor (136 aa), Fasta scores: E(): 9.5e-15, (52.4% identity in 105 aa overlap). Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CC06;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1330423	1331178	.	+	0	Locus=ML1139;Name=atpB;Function=;Product=PROBABLE ATP SYNTHASE A CHAIN ATPB (PROTEIN 6);Comments=ML1139, len: 251 aa. Probable atpB, ATP synthase A chain protein (EC 3.6.3.14). Identical to the previously sequenced Mycobacterium leprae ATP synthase A chain (EC 3.6.1.34) SW:ATP6_MYCLE (P45829) (251 aa), Fasta scores: E(): 0, 100.0% identity in 251 aa overlap. Also highly similar to many other Prokaryotic and Eukaryotic proposed ATPase A chain family proteins e.g. Mycobacterium tuberculosis Rv1304 SW:ATP6_MYCTU (Q10591) (250 aa), Fasta scores: E(): 0, 84.0% identity in 250 aa overlap and Nicotiana tabacum (Common tobacco) SW:ATPI_TOBAC (P06288) (247 aa), Fasta scores: E(): 3.3e-18, 32.5% identity in 246 aa overlap. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00119 ATP-synt_A, ATP synthase A chain. Contains PS00449 ATP synthase a subunit signature.;UniProt_AC=P45829;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1337568	1337933	.	+	0	Locus=ML1146;Name=atpC;Function=;Product=PROBABLE ATP SYNTHASE EPSILON CHAIN ATPC;Comments=ML1146, len: 121 aa. Probable atpC, ATP synthase [epsilon] chain (EC 3.6.3.14). Identical to the previously sequenced Mycobacterium leprae ATP synthase epsilon chain SW:ATPE_MYCLE (P45822) (124 aa), Fasta scores: E(): 0, 100.0% identity in 121 aa overlap. Also highly similar to many other proposed ATPase epsilon chain family proteins e.g. Mycobacterium tuberculosis Rv1311 SW:ATPE_MYCTU (Q10595) (121 aa), Fasta scores: E(): 0, 87.6% identity in 121 aa overlap and Bacillus firmus SW:ATPE_BACFI (P22480) (133 aa), Fasta scores: E(): 6.3e-09, 41.3% identity in 104 aa overlap. Contains Pfam match to entry PF00401 ATP-synt_DE, ATP synthase, Delta/Epsilon chain.;UniProt_AC=P45822;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1718073	1718622	.	-	0	Locus=ML1432c;Name=pncA;Function=;Product=Pyrazinamidase/nicotinamidase PncA (pseudogene);Comments=ML1432c, len: 550 bp. Possible pseudogene of M. tuberculosis orthologue pncA|Rv2043c (561 bp) (Best blastx scores: 195).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1753337	1753870	.	+	0	Locus=ML1459;Name=ML1459;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1459, len: 534 bp. Possible pseudogene similar to M. tuberculosis Rv0791c (1044 bp) (Best blastx scores: 114).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1753886	1755874	.	-	0	Locus=ML1460c;Name=ML1460c;Function=;Product=Probable cyclase (adenylyl- or guanylyl-cyclase) (pseudogene);Comments=ML1460c, len: 1989 bp. Possible pseudogene of M. tuberculosis orthologue Rv2435c (2193 bp) (Best blastx scores: 545).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2629352	2629934	.	+	0	Locus=ML2212;Name=ML2212;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2212, len: 583 bp. Possible pseudogene of M. tuberculosis orthologue Rv0802c (657 bp) (Best blastx scores: 180).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2674581	2675349	.	-	0	Locus=ML2251c;Name=ML2251c;Function=;Product=Possible enoyl-CoA hydratase (pseudogene);Comments=ML2251c, len: 769 bp. Possible pseudogene similar to M. tuberculosis echA13|Rv1935c (957 bp) (Best blastx scores: 169).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1758795	1759161	.	+	0	Locus=ML1462;Name=ML1462;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1462, len: 367 bp. Possible pseudogene of M. tuberculosis orthologue Rv2437 (420 bp) (Best blastx scores: 173).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1794949	1796947	.	+	0	Locus=ML1490;Name=fadH;Function=;Product=Probable NADPH-dependent 2,4-Dienoyl-CoA reductase FadH (pseudogene);Comments=ML1490, len: 1999 bp. Possible pseudogene of M. tuberculosis orthologue fadH|Rv1175c  (2025 bp) (Best blastx scores: 466).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2678870	2679429	.	+	0	Locus=ML2255;Name=ML2255;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2255, len: 560 bp. Possible pseudogene of M. tuberculosis orthologue Rv3491 (579 bp) (Best blastx scores: 304).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	986477	987766	.	+	0	Locus=ML0831;Name=dgt;Function=;Product=PROBABLE DEOXYGUANOSINE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DGT (DGTPASE) (DGTP TRIPHOSPHOHYDROLASE);Comments=ML0831, len: 429 aa. Probable dgt, deoxyguanosine triphosphate triphosphohydrolase (EC 3.1.5.1). Similar to Rv2344c|MTCY98.13c|DGTP_MYCTU|P95240 Mycobacterium tuberculosis deoxyguanosinetriphosphate triphosphohydrolase dgt(431 aa) fasta scores: E(): 0, 83.8% identity in 421 aa and to many hypothetical deoxyguanosine hydrolases. Contains Pfam match to entry PF01966 HD, HD domain. BELONGS TO THE DGTPASE FAMILY.;UniProt_AC=Q9CCG3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2675774	2676010	.	-	0	Locus=ML2252c;Name=ML2252c;Function=;Product=hypothetical protein;Comments=ML2252c, len: 78 aa. Hypothetical unknown protein.;UniProt_AC=Q50165;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1221790	1222077	.	+	0	Locus=ML1056;Name=esxL1;Function=;Product=Putative ESAT-6 like protein EsxL1 (ESAT-6 LIKE PROTEIN 4);Comments=ML1056, len: 95 aa. Probable esxL1, ESAT-6 like protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein Q49946|U15180 (95 aa), Fasta scores: E(): 0, (100.0% identity in 95 aa overlap). Also similar to several putative Esat-6 like proteins from M. tuberculosis e.g. O05300|ESXL_MYCTU ESAT-6 like protein esxL (94 aa), fasta scores: E(): 4.6e-24, (64.130% identity in 92 aa overlap). Identical to ML1180c a possible paralogue of M. tuberculosis esxL2. SEEMS TO BELONG TO THE ESAT6 FAMILY.;UniProt_AC=Q49946;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1940969	1941392	.	-	0	Locus=ML1619c;Name=ML1619c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1619c, len: 424 bp. Possible pseudogene of M. tuberculosis orthologue Rv2910c (444 bp) (Best blastx scores: 158).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1797213	1797468	.	+	0	Locus=ML1491;Name=ML1491;Function=;Product=Low molecular weight T-cell antigen TB8.4 homolog (pseudogene);Comments=ML1491, len: 256 bp. Possible pseudogene of M. tuberculosis orthologue Rv1174c|TB8.4 (333 bp) (Best blastx scores: 115).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1802958	1803563	.	+	0	Locus=ML1496;Name=ML1496;Function=;Product=Probable transcriptional regulatory protein (pseudogene);Comments=ML1496, len: 606 bp. Possible pseudogene of M. tuberculosis orthologue Rv1167c (606 bp) (Best blastx scores: 300).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1941439	1942675	.	-	0	Locus=ML1620c;Name=pknI;Function=;Product=Probable transmembrane serine-threonine protein kinase I PknI (pseudogene);Comments=ML1620c, len: 1237 bp. Possible pseudogene of M. tuberculosis orthologue pknI|Rv2914c (1758 bp) (Best blastx scores: 190).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1094379	1095815	.	+	0	Locus=ML0925;Name=glnA;Function=;Product=GLUTAMINE SYNTHETASE GLNA1 (GLUTAMINE SYNTHASE) (Glutamate--ammonia ligase 1) (GS-I);Comments=ML0925, len: 478 aa. Probable glnA, glutamine synthase class I (EC 6.3.1.2). Highly similar to many glutamine synthetases (EC 6.3.1.2) including examples from: Mycobacterium tuberculosis Rv2220 SW:GLN1_MYCTU (Q10377) (478 aa), Fasta scores: E(): 0, (91.8% identity in 478 aa overlap) and Salmonella typhimurium SW:GLNA_SALTY (P06201) (468 aa), Fasta scores: E(): 0, (51.5% identity in 474 aa overlap). Also similar to ML1631 from M. leprae. Contains Pfam match to entry PF00120 gln-synt, Glutamine synthetase. Contains PS00182 Glutamine synthetase class-I adenylation site. Contains PS00180 Glutamine synthetase signature 1. Contains PS00181 Glutamine synthetase putative ATP-binding region signature. Belongs to the glutamine synthetase family.;UniProt_AC=Q9CCD8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1942747	1943812	.	-	0	Locus=ML1621c;Name=ML1621c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1621c, len: 1066 bp. Possible pseudogene of M. tuberculosis orthologue Rv2915c (1113 bp) (Best blastx scores: 434).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1507580	1508365	.	+	0	Locus=ML1263;Name=hisF;Function=histidine biosynthesis pathway (fifth step). IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The hisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the hisH subunit [CATALYTIC ACTIVITY: 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + L-glutamine = imidazole-glycerol phosphate + 5-aminoimidazol-4-carboxamide ribonucleotide + L-glutamate + H2O]. ;Product=Imidazole glycerol phosphate synthase subunit HisF (IGP synthase cyclase subunit) (IGP synthase subunit hisF) (ImGP synthase subunit hisF);Comments=ML1263, len: 261 aa. Probable hisF, Imidazole glycerol phosphate synthase subunity. Highly similar to many cyclases involved in histidine biosynthesis including: Mycobacterium tuberculosis Rv1605 SW:HIS6_MYCTU (O53908) (267 aa), Fasta scores: E(): 0, 89.8% identity in 256 aa overlap and Bacillus subtilis SW:HIS6_BACSU (O34727) (252 aa), Fasta scores: E(): 0, 53.0% identity in 253 aa overlap. Contains Pfam match to entry PF00977 His_biosynth, Histidine biosynthesis protein. Belongs to the hisA / hisF family.;UniProt_AC=Q9X7C2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2003274	2003854	.	+	0	Locus=ML1662;Name=ML1662;Function=;Product=Probable integral membrane protein (pseudogene);Comments=ML1662,  len: 581 bp. Possible pseudogene of M. tuberculosis orthologue Rv2963 (Best blastx scores: 136).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1517444	1518436	.	+	0	Locus=ML1274;Name=lgt;Function=;Product=Possible prolipoprotein diacylglyceryl transferases Lgt;Comments=ML1274, len: 330 aa. Possible lgt, prolipoprotein diacylglyceryl transferase (EC 2.4.99.-). Similar to many prolipoprotein diacylglyceryl transferases constituting the first step in lipoprotein biosynthesis e.g. Staphylococcus aureus SW:LGT_STAAU (P52282) (279 aa), Fasta scores: E(): 3.3e-12, 30.6% identity in 258 aa overlap and Mycobacterium tuberculosis Rv1614 TR:O06131 (EMBL:Z95554) (468 aa), Fasta scores: E(): 0, 75.5% identity in 322 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01790 LGT, Prolipoprotein diacylglyceryl transferase.;UniProt_AC=Q9CC52;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1736403	1738010	.	-	0	Locus=ML1442c;Name=ML1442c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1442c, len: 1608 bp. Possible pseudogene of M. tuberculosis orthologue Rv2052c (1605 bp) (Best blastx scores: 832).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1719468	1719678	.	-	0	Locus=ML1433c;Name=ML1433c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1433c, len: 211 bp. Possible pseudogene of M. tuberculosis orthologue Rv2044c (318 bp) (Best blastx scores: 110).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	958885	960108	.	-	0	Locus=ML0810c;Name=ML0810c;Function=;Product=Possible secreted protein;Comments=ML0810c, len: 407 aa. Possible secreted protein. Similar to O05854|Z9512|Rv3212|MTCY07D11.14c Mycobacterium tuberculosis hypothetical 42.5 kDa protein (407 aa), fasta scores: E(): 0, 79.9% identity in 407 aa. Contains N-terminal hydrophobic region.;UniProt_AC=Q9CCH4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1706395	1706748	.	+	0	Locus=ML1420;Name=ML1420;Function=;Product=hypothetical protein;Comments=ML1420, len: 117 aa. Hypothetical unknown protein.;UniProt_AC=O32948;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1056244	1057491	.	+	0	Locus=ML0890;Name=ML0890;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML0890, len: 415 aa. Conserved hypothetical protein.  Highly similar, to Mycobacterium tuberculosis hypothetical protein TR:O53518 (EMBL:AL021957) (379 aa), Fasta scores: E(): 0, 79.4% identity in 378 aa overlap and weakly similar to many anion-transporting ATPases e.g. SW:ARA2_ECOLI (SW:P52145) (583 aa), Fasta scores: E(): 5.2e-07, 29.6% identity in 314 aa overlap. Previously sequenced as Mycobacterium leprae hypothetical protein TR:O69574 (EMBL:AL022602) (415 aa), Fasta scores: E(): 0, 99.8% identity in 415 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O69574;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1748923	1749217	.	+	0	Locus=ML1455;Name=ML1455;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1455, len: 295 bp. Possible pseudogene of M. tuberculosis orthologue Rv2422 (273 bp) (Best blastx scores: 96).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2248201	2248719	.	-	0	Locus=ML1868c;Name=ML1868c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1868c, len: 519 bp. Possible pseudogene of M. tuberculosis orthologue Rv0695 (756 bp) (Best blastx scores: 251).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1295914	1298535	.	+	0	Locus=ML1120;Name=ML1120;Function=;Product=conserved hypothetical protein;Comments=ML1120, len: 873 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1278 SW:YC78_MYCTU (Q11042) (875 aa), Fasta scores: E(): 0, 69.5% identity in 872 aa overlap. Contains multiple possible coiled-coils. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CC83;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1445950	1446669	.	-	0	Locus=ML1224c;Name=ML1224c;Function=;Product=conserved hypothetical protein;Comments=ML1224c, len: 239 aa. Conserved hypothetical protein. Previously sequenced Mycobacterium leprae hypothetical protein  TR:Q49628 (EMBL:U00010) (286 aa), Fasta scores: E(): 0, 100.0% identity in 233 aa overlap. Also highly similar toseveral other proteins of unproven function including: Mycobacterium tuberculosis hypothetical protein Rv1593c TR:O06597 (EMBL:Z95586) (236 aa), Fasta scores: E(): 0, 85.7% identity in 238 aa overlap and Streptomyces coelicolor TR:Q9S233 (EMBL:AL109848) (239 aa), Fasta scores: E(): 1.1e-19, 38.2% identity in 191 aa overlap putative DNA hydrolase.;UniProt_AC=Q9CC66;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1077593	1079146	.	+	0	Locus=ML0910;Name=murF;Function=;Product=ProbableUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF;Comments=ML0910, len: 517 aa. Probable murF, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase (EC 6.3.2.15). Identical to the previously sequenced Mycobacterium leprae hypothetical protein UDP-N-acetylmuramoylalanyl-D-glutamyl -2,6-diaminopimelate--D-alanyl-D-alanyl ligase TR:O69556 (EMBL:AL022602) (517 aa), Fasta scores: E(): 0, 100.0% identity in 517 aa overlap. Also highly similar to MurF orthologues from Mycobacterium tuberculosis Rv2157c SW:MURF_MYCTU (SW:O06220) (510 aa), Fasta scores: E(): 0, 75.5% identity in 531 aa overlap and Escherichia coli SW:MURF_ECOLI (SW:P11880) (452 aa), Fasta scores: E(): 1.7e-09, 31.0% identity in 519 aa overlap. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family.;UniProt_AC=O69556;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1774190	1775245	.	-	0	Locus=ML1473c;Name=ML1473c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1473c, len: 1056 bp. Possible pseudogene of M. tuberculosis orthologue Rv2449c (1260 bp) (Best blastx scores: 203).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1567074	1567367	.	-	0	Locus=ML1314c;Name=ML1314c;Function=;Product=conserved hypothetical protein;Comments=ML1314c, len: 97 aa. Conserved hypothetical protein. Highly similar to several proteins of unknown function e.g. Mycobacterium tuberculosis Rv2117 TR:O33252 (EMBL:Z97559) (97 aa), Fasta scores: E(): 0, 85.6% identity in 97 aa overlap.;UniProt_AC=Q49798;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1757789	1758499	.	+	0	Locus=ML1461;Name=rbsK;Function=;Product=Ribokinase RbsK (pseudogene);Comments=ML1461, len: 711 bp. Possible pseudogene of M. tuberculosis orthologue rbsK|Rv2436 (915 bp) (Best blastx scores: 102).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1697094	1697815	.	+	0	Locus=ML1415;Name=pks10;Function=;Product=Possible chalcone synthase Pks10 (pseudogene);Comments=ML1415, len: 722 bp. Possible pseudogene of M. tuberculosis orthologue pks10|Rv1660 (1062 bp) (Best blastx scores: 265).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1697969	1699251	.	+	0	Locus=ML1416;Name=pks7;Function=;Product=Probable polyketide synthase Pks7 (pseudogene);Comments=ML1416, len: 1283 bp. Possible pseudogene of M. tuberculosis orthologue pks7|Rv1661 (6381 bp) (Best blastx scores: 371).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1810607	1814267	.	-	0	Locus=ML1502c;Name=narG;Function=;Product=Probable respiratory nitrate reductase (alpha chain) NarG (pseudogene);Comments=ML1502c, len: 3661 bp. Possible pseudogene of M. tuberculosis orthologue narG|Rv1161 (3699 bp) (Best blastx scores: 864).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1837226	1837627	.	-	0	Locus=ML1522c;Name=ML1522c;Function=;Product=Probable short-chain dehydrogenase/reductase (pseudogene);Comments=ML1522c, len: 402 bp. Possible pseudogene of M. tuberculosis orthologue Rv2766c (783 bp) (Best blastx scores: 209).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1551423	1552168	.	+	0	Locus=ML1303;Name=ML1303;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML1303, len: 746 bp. Possible pseudogene of M. tuberculosis orthologue Rv2129c (882 bp) (Best blastx scores: 193).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1609370	1609928	.	-	0	Locus=ML1348c;Name=ML1348c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1348c, len: 559 bp. Possible pseudogene of M. tuberculosis orthologue Rv1685c (624 bp) (Best blastx scores: 335).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1577421	1577659	.	+	0	Locus=ML1324;Name=ML1324;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1324, len: 239 bp. Possible pseudogene of M. tuberculosis orthologue Rv2104c (255 bp) (Best blastx scores: 174).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1617920	1618105	.	+	0	Locus=ML1357;Name=ML1357;Function=;Product=conserved hypothetical protein;Comments=ML1357, len: 61 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis Rv1693 TR:O33195 (EMBL:Z98268) (58 aa), Fasta scores: E(): 9.7e-13, 73.8% identity in 61 aa overlap.;UniProt_AC=Q9CC31;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1609118	1609351	.	+	0	Locus=ML1347;Name=ML1347;Function=;Product=conserved hypothetical protein;Comments=ML1347, len: 77 aa. Conserved hypothetical protein. Highly similar to proteins of unknown function from Mycobacterium tuberculosis Rv1684 TR:O33186 (EMBL:Z98268) (74 aa), Fasta scores: E(): 6.9e-20, 70.1% identity in 77 aa overlap and Streptomyces coelicolor TR:CAB88911 (EMBL:AL353862) (56 aa), Fasta scores: E(): 0.0064, 48.2% identity in 56 aa overlap.;UniProt_AC=Q9CC33;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1540168	1540330	.	-	0	Locus=ML1291c;Name=ML1291c;Function=;Product=Probable transposase (pseudogene);Comments=ML1291c, len: 163 bp. Possible pseudogene similar to several M. tuberculosis transposases associated with IS6110 (Best blastx scores: 75) and identical to ML1820A, ML0599A, ML1820A, ML0568B from M. leprae.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1544613	1545659	.	-	0	Locus=ML1295c;Name=lppL;Function=;Product=Probable conserved lipoprotein LppL (pseudogene);Comments=ML1295c, len: 1047 bp. Possible pseudogene similar to M. tuberculosis orthologue lppL|Rv2138 (1077 bp) (Best blast scores: 1243).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1563417	1563705	.	+	0	Locus=ML1311;Name=ML1311;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML1311, len: 289 bp. Possible pseudogene of M. tuberculosis orthologue Rv2120c (483 bp) (Best blastx scores: 151).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1570099	1570395	.	-	0	Locus=ML1317c;Name=ML1317c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1317c, len: 297 bp. Possible pseudogene of M. tuberculosis orthologue Rv2114 (624 bp) (Best blastx scores: 169).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1588162	1589095	.	-	0	Locus=ML1335c;Name=ML1335c;Function=;Product=Probable 5'-3' exonuclease (pseudogene);Comments=ML1335c, len: 934 bp. Possible pseudogene of M. tuberculosis orthologue Rv2090 (1182 bp) (Best blastx scores: 363).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1609957	1610609	.	-	0	Locus=ML1349c;Name=ML1349c;Function=;Product=Probable conserved integral membrane protein ABC transporter (pseudogene);Comments=ML1349c, len: 653 bp. Possible pseudogene of M. tuberculosis orthologue Rv1686c (681 bp) (Best blastx scores: 406).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1636181	1636916	.	+	0	Locus=ML1375;Name=ML1375;Function=;Product=Probable transcriptional regulator (IclR family) (pseudogene);Comments=ML1375, len: 736 bp. Possible pseudogene of M. tuberculosis orthologue Rv1719 (780 bp) (Best blastx scores: 433).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1639504	1641271	.	+	0	Locus=ML1376;Name=ML1376;Function=;Product=Possible transferase (pseudogene);Comments=ML1376, len: 1768 bp. Possible pseudogene similar to M. tuberculosis Rv3225c (1425 bp) (Best blastx scores: 314).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1687137	1687463	.	-	0	Locus=ML1405c;Name=ML1405c;Function=;Product=transposase (pseudogene);Comments=ML1405c, len: 327 bp. Possible pseudogene similar to many transposases e.g. Q53053 from Rhodococcus, Q48344 (carried on IS6120) from Mycobacterium smegmatis and Q9ZA68 (carried on IS666) from Mycobacterium avium.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1577745	1578182	.	+	0	Locus=ML1325;Name=ML1325;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1325, len: 438 bp. Possible pseudogene of M. tuberculosis orthologue Rv2103c (435 bp) (Best blastx scores: 404).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1768622	1768993	.	-	0	Locus=ML1470c;Name=ML1470c;Function=;Product=PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN;Comments=ML1470c, len: 123 aa. Probable conserved integral membrane protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2446c TR:O53173 (EMBL:AL021246) (123 aa), Fasta scores: E(): 1.5e-22, 66.7% identity in 108 aa overlap.;UniProt_AC=Q9CBY9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1686378	1687126	.	-	0	Locus=ML1404c;Name=ML1404c;Function=;Product=transposase (pseudogene);Comments=ML1404c, len: 749 bp.  Possible pseudogene similar to many transposases e.g. Q53052 from Rhodococcus, TRA0_MYCSM|P35883 (carried on IS6120) from Mycobacterium smegmatis and Q9ZA68 (carried on IS666) from Mycobacterium avium. Also similar to several transposases from M. tuberculosis Rv3115, Rv3023c, Rv2512, Rv3431c etc.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1631209	1631880	.	+	0	Locus=ML1371;Name=cmk;Function=;Product=Probable Cytidylate kinase Cmk (CMP kinase) (Cytidine monophosphate kinase) (CK);Comments=ML1371, len: 223 aa. Probable cmk, Cytidylate kinase (EC 2.7.4.14).  Highly similar to several cytidylate kinases including: Bacillus subtilis SW:KCY_BACSU (P38493) (224 aa), Fasta scores: E(): 1.9e-28, 42.7% identity in 218 aa overlap and Mycobacterium tuberculosis Rv1712 TR:O33211 (EMBL:Z98268) (230 aa), Fasta scores: E(): 0, 74.8% identity in 222 aa overlap. Contains Pfam match to entry PF02224 Cytidylate_kin, Cytidylate kinase. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q49885;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1538218	1539644	.	+	0	Locus=ML1290;Name=ML1290;Function=;Product=Conserved 13E12 repeat family protein (pseudogene);Comments=ML1290, len: 1427 bp. Possible pseudogene similar to M. tuberculosis 13E12 repeat family e.g. Rv0336 or Rv0515 (Best blastx scores: 367), also similar to M. leprae ML1850 pseudogene.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1578225	1578728	.	-	0	Locus=ML1326c;Name=ML1326c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1326c, len: 504 bp. Possible pseudogene of M. tuberculosis orthologue Rv2102 (717 bp) (Best blastx scores: 126).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1578934	1579641	.	-	0	Locus=ML1327c;Name=ML1327c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1327c, len: 708 bp. Possible pseudogene of M. tuberculosis orthologue Rv2100 (1653 bp), member of M. tuberculosis REP13E12 repeat family (Best blastx scores: 212).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2248752	2249883	.	-	0	Locus=ML1869c;Name=lldD1;Function=;Product=Possible L-lactate dehydrogenase (cytochrome) LldD1 (pseudogene);Comments=ML1869c, len: 1132 bp. Possible pseudogene of M. tuberculosis orthologue lldD1|Rv0694 (1191 bp) (Best blastx scores: 506).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1540616	1540858	.	-	0	Locus=ML1292c;Name=ML1292c;Function=;Product=conserved hypothetical protein;Comments=ML1292c, len: 80 aa. Conserved hypothetical protein, identical to the other hypothetical CDS ML0568A and ML0599B from M. leprae.;UniProt_AC=O33140;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1544359	1544613	.	-	0	Locus=ML1294c;Name=ML1294c;Function=;Product=conserved hypothetical protein;Comments=ML1294c, len: 84 aa. Conserved hypothetical protein, similar to Q9AD94 Hypothetical protein SCO1673 from Streptomyces coelicolor (62 aa), fasta scores: E(): 0.00042, (44.000% identity  in 50 aa overlap).;UniProt_AC=Q9CC44;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1545744	1546079	.	+	0	Locus=ML1296;Name=ML1296;Function=;Product=conserved hypothetical protein;Comments=ML1296, len: 111 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv2137c TR:O06238 (EMBL:Z95388) (137 aa), Fasta scores: E(): 1.3e-28, 75.5% identity in 106 aa overlap.;UniProt_AC=Q9CC43;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1547795	1548385	.	+	0	Locus=ML1299;Name=ML1299;Function=;Product=conserved hypothetical protein;Comments=ML1299, len: 196 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2134c TR:O06241 (EMBL:Z95388) (195 aa), Fasta scores: E(): 0, 91.1% identity in 192 aa overlap.;UniProt_AC=Q49789;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1548396	1549184	.	+	0	Locus=ML1300;Name=ML1300;Function=;Product=conserved hypothetical protein;Comments=ML1300, len: 262 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2133c TR:O06242 (EMBL:Z95388) (262 aa), Fasta scores: E(): 0, 79.4% identity in 262 aa overlap.;UniProt_AC=Q9CC40;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1570553	1571558	.	-	0	Locus=ML1318c;Name=ML1318c;Function=;Product=Probable integral membrane protein (pseudogene);Comments=ML1318c, len: 1006 bp. Possible pseudogene of M. tuberculosis orthologue Rv2113 (1194 bp) (Best blastx scores: 211).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1565157	1566041	.	-	0	Locus=ML1312c;Name=ML1312c;Function=;Product=conserved hypothetical protein;Comments=ML1312c, len: 294 aa. Conserved hypothetical protein. Highly similar to several proteins of unknown function e.g. Mycobacterium tuberculosis Rv2119 TR:O33254 (EMBL:Z97559) (278 aa), Fasta scores: E(): 0, 79.9% identity in 278 aa overlap.;UniProt_AC=Q9S377;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1733351	1733686	.	+	0	Locus=ML1439;Name=ML1439;Function=;Product=conserved hypothetical protein;Comments=ML1439, len: 111 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2050 TR:O53492 (EMBL:AL021899) (111 aa), Fasta scores: E(): 0, 97.3% identity in 111 aa overlap.;UniProt_AC=Q9CC05;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1645074	1645637	.	+	0	Locus=ML1380;Name=ML1380;Function=;Product=conserved hypothetical protein;Comments=ML1380, len: 187 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1780 TR:O53931 (EMBL:AL022021) (187 aa), Fasta scores: E(): 0, 82.4% identity in 187 aa overlap.;UniProt_AC=Q49881;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1561970	1562251	.	+	0	Locus=ML1309;Name=hisE;Function=;Product=Probable phosphoribosyl-AMP pyrophosphatase HisE;Comments=ML1309, len: 93 aa. Probable phosphoribosyl-AMP pyrophosphatase (EC 3.6.1.31). Highly similar to several phosphoribosyl-ATP pyrophosphatases involved in histidine biosynthesis, including: Sulfolobus solfataricus HisE SW:HIS2_SULSO (O33776) (94 aa), Fasta scores: E(): 0.00013, 32.5% identity in 83 aa overlap and Mycobacterium tuberculosis Rv2122c|HIS2_MYCTU (O33257) (93 aa), Fasta scores: E(): 2.5e-31, 86.0% identity in 93 aa overlap. Contains Pfam match to entry PF01503 PRA-PH, Phosphoribosyl-ATP pyrophosphohydrolase.;UniProt_AC=Q49786;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1589276	1590275	.	+	0	Locus=ML1336;Name=pepE;Function=;Product=Probable dipeptidase PepE (pseudogene);Comments=ML1336, len: 1000 bp. Possible pseudogene of M. tuberculosis orthologue pepE|Rv2089c (1128 bp) (Best blastx scores: 243).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1595006	1595367	.	-	0	Locus=ML1337c;Name=ML1337c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1337c, len: 362 bp. Possible pseudogene of M. tuberculosis orthologue Rv2674 (411 bp) (Best blastx scores: 159).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1738026	1738485	.	-	0	Locus=ML1443c;Name=ML1443c;Function=;Product=Probable transmembrane protein (pseudogene);Comments=ML1443c, len: 460 bp. Possible pseudogene of M. tuberculosis orthologue Rv2053c (528 bp) (Best blastx scores: 166).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1848860	1850743	.	-	0	Locus=ML1533c;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML1533c, len: 1883 bp. Possible pseudogene of M. tuberculosis orthologue PPE31|Rv1807 (1200 bp) (Best blastx scores: 229).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1599258	1600329	.	+	0	Locus=ML1341;Name=ML1341;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1341, len: 1072 bp. Possible pseudogene of M. tuberculosis orthologue Rv2670c (1110 bp) (Best blastx scores: 1011).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1600322	1600505	.	-	0	Locus=ML1342c;Name=ML1342c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1342c, len: 184 bp. Possible pseudogene of M. tuberculosis orthologue Rv2669 (471 bp) (Best blastx scores: 87).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1600581	1600662	.	-	0	Locus=ML1343c;Name=ML1343c;Function=;Product=Possible exported alanine and valine rich protein (pseudogene);Comments=ML1343c, len: 82 bp. Possible pseudogene of M. tuberculosis orthologue Rv2668 (522 bp) (Best blastx scores: 131).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1604188	1605805	.	+	0	Locus=ML1345;Name=ML1345;Function=;Product=Probable transcriptional regulatory protein (LuxR family) (pseudogene);Comments=ML1345, len: 1618 bp. Possible pseudogene similar to several M. tuberculosis transcriptional regulators e.g. Rv0890c and Rv1358 (Best blastx scores: 327).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1576557	1577354	.	+	0	Locus=ML1323;Name=prcA;Function=;Product=probable proteasome (alpha subunit) PrcA;Comments=ML1323, len: 265 aa. Probable prcA, proteasome (alpha subunit 0 (EC 3.4.25.1). Highly similar to many proposed 20S proteasome alpha subunits including: Rhodococcus sp. TR:Q53080 (EMBL:U26421) (259 aa), Fasta scores: E(): 0, 65.5% identity in 255 aa overlap and Mycobacterium tuberculosis Rv2109c TR:O33244 (EMBL:Z97559) (248 aa), Fasta scores: E(): 0, 91.8% identity in 244 aa overlap.;UniProt_AC=Q9S375;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1587326	1588144	.	+	0	Locus=ML1334;Name=ML1334;Function=;Product=possible conserved membrane protein;Comments=ML1334, len: 272 aa. Possible conserved membrane protein. Highly similar to several e.g. Mycobacterium tuberculosis hypothetical protein Rv2091c SW:YK91_MYCTU (Q10700) (244 aa), Fasta scores: E(): 0, 62.9% identity in 272 aa overlap. Note the product of this CDS contains a 7xPGQYG(P/S) repeat region similar to several bacterial protein calcium binding domains. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9ZBD7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1613461	1614911	.	-	0	Locus=ML1353c;Name=ML1353c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1353c, len: 1451 bp. Possible pseudogene of M. tuberculosis orthologue Rv1376 (1494 bp) (Best blastx scores: 348).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1615067	1615299	.	-	0	Locus=ML1354c;Name=ML1354c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1354c, len: 233 bp. Possible pseudogene of M. tuberculosis orthologue Rv1375 (1320 bp) (Best blastx scores: 110).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1616275	1616817	.	+	0	Locus=ML1355;Name=ML1355;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1355, len: 543 bp. Possible pseudogene of M. tuberculosis orthologue Rv1691 (753 bp) (Best blastx scores: 306).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1616893	1617920	.	+	0	Locus=ML1356;Name=ML1356;Function=;Product=Probable phosphatase (pseudogene);Comments=ML1356, len: 1028 bp. Possible pseudogene of M. tuberculosis orthologue Rv1692 (1062 bp) (Best blastx scores: 433).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1740515	1740793	.	-	0	Locus=ML1447c;Name=cobN;Function=;Product=Probable cobalamin biosynthesis protein CobN (pseudogene);Comments=ML1447c, len: 279 bp. Possible pseudogene of M. tuberculosis orthologue cobN|Rv2062c (3585 bp) (Best blastx scores: 284).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1625921	1626533	.	+	0	Locus=ML1364;Name=ML1364;Function=;Product=Nudix hydrolase (pseudogene);Comments=ML1364, len: 613 bp. Possible pseudogene of M. tuberculosis orthologue Rv1700 (624 bp) (Best blastx scores: 554).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1602986	1603246	.	-	0	Locus=ML1344c;Name=ML1344c;Function=;Product=Hypothetical unknown protein;Comments=ML1344c, len: 86 aa. Hypothetical unknown protein (doubtful CDS).;UniProt_AC=Q9CC35;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2012870	2013061	.	+	0	Locus=ML1668B;Name=ML1668B;Function=;Product=Conserved hypothetical protein;Comments=ML1668B, len: 63 aa. Conserved hypothetical protein. Highly similar to the N-terminal region of Rv2970a Conserved hypothetical protein (56 aa), fasta scores: E(): 8.2e-11, (68.421% identity in 38 aa overlap) and Mb2995 from M. bovis (56 aa).;UniProt_AC=;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1596795	1598372	.	-	0	Locus=ML1339c;Name=ML1339c;Function=;Product=POSSIBLE SECRETED PROTEASE;Comments=ML1339c, len: 525 aa. Possible secreted protease. Highly similar to several proteases including: Streptomyces lividans TR:Q54399 (EMBL:L42759) (513 aa), Fasta scores: E(): 2.7e-19, 25.7% identity in 548 aa overlap and Mycobacterium tuberculosis Rv2672 TR:P71969 (EMBL:Z80225) (528 aa), Fasta scores: E(): 0, 74.4% identity in 528 aa overlap. Contains a possible N-terminal signal sequence.;UniProt_AC=O05685;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1627537	1627728	.	-	0	Locus=ML1366c;Name=ML1366c;Function=;Product=Probable catechol-o-methyltransferase (pseudogene);Comments=ML1366c, len: 192 bp. Possible pseudogene of M. tuberculosis orthologue Rv1703c (591 bp) (Best blastx scores: 219).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1741637	1742219	.	-	0	Locus=ML1449c;Name=cobK;Function=;Product=Probable precorrin-6X reductase CobK (pseudogene);Comments=ML1449c, len: 583 bp. Possible pseudogene of M. tuberculosis orthologue cobK|Rv2070c (735 bp) (Best blastx scores: 178).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1742243	1742978	.	-	0	Locus=ML1450c;Name=cobM;Function=;Product=Probable precorrin-4 C11-methyltransferase CobM (pseudogene);Comments=ML1450c, len: 736 bp. Possible pseudogene of M. tuberculosis orthologue cobM|Rv2071c (756 bp) (Best blastx scores: 341).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1633391	1634438	.	-	0	Locus=ML1373c;Name=ML1373c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1373c, len: 1048 bp. Possible pseudogene similar to the M. tuberculosis degenerate repetitive element REP13E12 family e.g. Rv1702c (1365 bp) (Best blastx scores: 97).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1635167	1635838	.	+	0	Locus=ML1374;Name=ML1374;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1374, len: 672 bp. Possible pseudogene of M. tuberculosis orthologue Rv1716 (831 bp) (Best blastx scores: 261).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1641396	1641861	.	+	0	Locus=ML1377;Name=ML1377;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1377, len: 466 bp. Possible pseudogene of M. tuberculosis orthologue Rv1769 (1245 bp) (Best blastx scores: 218).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1641984	1643179	.	+	0	Locus=ML1378;Name=ML1378;Function=;Product=conserved hypothetical protein (pseudogene);Comments=ML1378, len: 1196 bp. Possible pseudogene of M. tuberculosis orthologue Rv1770 (1287 bp) (Best blastx scores: 305).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1643196	1644454	.	+	0	Locus=ML1379;Name=ML1379;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML1379, len: 1259 bp. Possible pseudogene of M. tuberculosis orthologue Rv1771 (1287 bp) (Best blastx scores: 462).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1618113	1618922	.	+	0	Locus=ML1358;Name=tlyA;Function=;Product=cytotoxin/hemolysin homologue TlyA;Comments=ML1358, len: 269 aa. Probable tlyA, cytotoxin/haemolysin homologue. Highly similar to several proposed hemolysins including: Mycobacterium ulcerans TlyA TR:CAB83047 (EMBL:AJ271681) (281 aa), Fasta scores: E(): 0, 81.0% identity in 268 aa overlap, Treponema hyodysenteriae hemolysin A SW:HLYA_TREHY (Q06803) (240 aa), Fasta scores: E(): 2.3e-23, 34.9% identity in 238 aa overlap and Mycobacterium tuberculosis Rv1694 TR:Q50760 (EMBL:X98295) (268 aa), Fasta scores: E(): 0, 78.4% identity in 268 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=O05676;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1656694	1659194	.	-	0	Locus=ML1385c;Name=ML1385c;Function=;Product=Probable conserved transmembrane ATP-binding protein ABC transporter (pseudogene);Comments=ML1385c, len: 2501 bp. Possible pseudogene of M. tuberculosis orthologue Rv1747 (2598 bp) (Best blastx scores: 280).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1659700	1660593	.	+	0	Locus=ML1386;Name=pknF;Function=;Product=Anchored membrane serine-threonine protein kinase PknF (pseudogene);Comments=ML1386, len: 894 bp. Possible pseudogene of M. tuberculosis orthologue pknF|Rv1746 (1431 bp) (Best blastx scores: 407). Also similar to ML1266c a possible pseudogene similar to M. tuberculosis pknF.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1663851	1665183	.	+	0	Locus=ML1388;Name=ML1388;Function=;Product=Possible drug efflux membrane protein (pseudogene);Comments=ML1388, len: 1333 bp. Possible pseudogene of M. tuberculosis orthologue Rv1634 (1416 bp) (Best blastx scores: 456).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1743125	1745194	.	+	0	Locus=ML1450A;Name=ML1450A;Function=;Product=Probable conserved transmembrane transport protein (pseudogene);Comments=ML1450A, len: 2070 bp. Possible pseudogene similar to several M. tuberculosis conserved transmembrane transport proteins e.g. Rv1557, Rv0676c, Rv2942, Rv2339 etc (Best blastx score: 277).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1678047	1679058	.	-	0	Locus=ML1398c;Name=ML1398c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1398c, len: 1012 bp. Possible pseudogene of M. tuberculosis orthologue Rv1645c (1056 bp) (Best blastx scores: 740).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1680236	1680659	.	+	0	Locus=ML1400;Name=ML1400;Function=;Product=Probable transmembrane protein (pseudogene);Comments=ML1400, len: 424 bp. Possible pseudogene of M. tuberculosis orthologue Rv1648 (807 bp) (Best blastx scores: 139).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2253010	2253826	.	-	0	Locus=ML1874c;Name=ML1874c;Function=;Product=Putative ferredoxin reductase (pseudogene);Comments=ML1874c, len: 817 bp. Possible pseudogene of M. tuberculosis orthologue Rv0688 (Best blastx scores: 266).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1656229	1656567	.	+	0	Locus=ML1384;Name=ML1384;Function=;Product=hypothetical protein;Comments=ML1384, len: 112 aa. Hypothetical unknown protein.;UniProt_AC=Q9CC28;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1745350	1746075	.	-	0	Locus=ML1451c;Name=ML1451c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1451c, len: 726 bp. Possible pseudogene of M. tuberculosis orthologue Rv2417c (843 bp) (Best blastx scores: 354).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1709621	1710382	.	-	0	Locus=ML1422c;Name=ML1422c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1422c, len: 762 bp. Possible pseudogene of M. tuberculosis orthologue Rv2033c (843 bp) (Best blastx scores: 279).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2772791	2773834	.	-	0	Locus=ML2338c;Name=ML2338c;Function=;Product=Probable lipase (pseudogene);Comments=ML2338c, len: 1044 bp. Possible pseudogene similar to M. tuberculosis lipD|Rv1923 (1341 bp) (Best blastx scores: 246).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2739770	2739877	.	-	0	Locus=ML2311c;Name=ML2311c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2311c, len: 108 bp. Possible pseudogene of M. tuberculosis orthologue Rv3688c (465 bp) (Best blastx scores: 125).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1694888	1696300	.	+	0	Locus=ML1413;Name=argH;Function=;Product=Probable Argininosuccinate lyase ArgH;Comments=ML1413, len: 470 aa. Probable argH, Argininosuccinate lyase (EC 4.3.2.1). Highly similar to many argininosuccinate lyases involved in arginine biosynthesis, including: Escherichia coli SW:ARLY_ECOLI (P11447) (172 aa), BlastP Expect 9.3 and Mycobacterium tuberculosis SW:ARLY_MYCTU (P94994) (470 aa), Fasta scores: E(): 0, 88.1% identity in 470 aa overlap. Contains Pfam match to entry PF00206 lyase_1, Lyase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00163 Fumarate lyases signature.;UniProt_AC=Q9CC09;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1720213	1721344	.	-	0	Locus=ML1434c;Name=lipT;Function=;Product=Probable carboxylesterase LipT (pseudogene);Comments=ML1434c, len: 1132 bp. Possible pseudogene of M. tuberculosis orthologue lipT|Rv2045c (1536 bp) (Best blastx scores: 360).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1721431	1722011	.	+	0	Locus=ML1435;Name=lppI;Function=;Product=Probable lipoprotein LppI (pseudogene);Comments=ML1435, len: 581 bp. Possible pseudogene of M. tuberculosis orthologue lppI|Rv2046 (657 bp) (Best blastx scores: 133).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1723812	1726138	.	-	0	Locus=ML1436c;Name=ML1436c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1436c, len: 2327 bp. Possible pseudogene of M. tuberculosis orthologue Rv2047c (2565 bp) (Best blastx scores: 1206).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1726368	1732457	.	-	0	Locus=ML1437c;Name=pks12;Function=;Product=Probable polyketide synthase Pks12 (pseudogene);Comments=ML1437c, len: 6090 bp. Possible pseudogene of M. tuberculosis orthologue pks12|Rv2048c (12456 bp) (Best blastx scores: 1700).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1732857	1733040	.	-	0	Locus=ML1438c;Name=ML1438c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1438c, len: 184 bp. Possible pseudogene of M. tuberculosis orthologue Rv2049c (225 bp) (Best blastx scores: 101).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2743453	2744139	.	+	0	Locus=ML2315;Name=ML2315;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2315, len: 687 bp. Possible pseudogene of M. tuberculosis orthologue Rv3698 (1530 bp) (Best blastx scores: 315).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1749447	1750789	.	-	0	Locus=ML1456c;Name=ML1456c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1456c, len: 1343 bp. Possible pseudogene of M. tuberculosis orthologue Rv2425c (1443 bp) (Best blastx scores: 490).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1750820	1751684	.	-	0	Locus=ML1457c;Name=ML1457c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1457c, len: 865 bp. Possible pseudogene of M. tuberculosis orthologue Rv2426c (876 bp) (Best blastx scores: 304).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1739655	1739879	.	-	0	Locus=ML1445c;Name=ML1445c;Function=;Product=hypothetical protein;Comments=ML1445c, len: 74 aa. Hypothetical unknown protein.;UniProt_AC=Q9CC03;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1738599	1739297	.	+	0	Locus=ML1444;Name=ML1444;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML1444, len: 232 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis Rv2054 TR:O86353 (EMBL:AL021899) Conserved hypothetical protein (237 aa), Fasta scores: E(): 0, 76.1% identity in 230 aa overlap. Weakly similar to several carboxymethylenebutenolidases (EC 3.1.1.45) involved in 3-chlorocatechol degradation e.g. Pseudomonas putida SW:CLCD_PSEPU (P11453) (236 aa), Fasta scores: E(): 7.6e-06, 28.6% identity in 234 aa overlap. Contains Pfam match to entry PF01738 DLH, Dienelactone hydrolase family.;UniProt_AC=Q9CC04;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1764507	1764818	.	-	0	Locus=ML1467c;Name=rplU;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L21 RPLU;Comments=ML1467c, len: 103 aa. Probable 50S ribosomal protein L21. Highly similar to many 50s ribosomal proteins (L21) including: Escherichia coli SW:RL21_ECOLI (P02422) (103 aa), Fasta scores: E(): 9.8e-11, 37.0% identity in 100 aa overlap and Mycobacterium tuberculosis Rv2442c SW:RL21_MYCTU (p71907) (104 aa), Fasta scores: E(): 0, 91.2% identity in 102 aa overlap. Contains Pfam match to entry PF00829 Ribosomal_L21p, Ribosomal prokaryotic L21 protein.;UniProt_AC=Q9CBZ2;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2876799	2877306	.	-	0	Locus=ML2405c;Name=pnp;Function=;Product=Probable 5'-methylthioadenosine phosphorylase Pnp (pseudogene);Comments=ML2405c, len: 508 bp. Possible pseudogene of M. tuberculosis orthologue pnp|Rv0535 (795 bp) (Best blastx scores: 196).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2878880	2880000	.	-	0	Locus=ML2408c;Name=ML2408c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2408c, len: 1121 bp. Possible pseudogene of M. tuberculosis orthologue Rv0530 (1218 bp) (Best blastx scores: 266).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1768162	1768572	.	-	0	Locus=ML1469c;Name=ndk;Function=;Product=PROBABLE NUCLEOSIDE DIPHOSPHATE KINASE NDK (NDK) (NDP KINASE) (NUCLEOSIDE-2-P KINASE);Comments=ML1469c, len: 136 aa. Probable nucleoside diphosphate kinases (EC 2.7.4.6). Highly similar to many nucleoside diphosphate kinases including: Bacillus subtilis SW:NDK_BACSU (P31103) (149 aa), Fasta scores: E(): 5e-27, 55.7% identity in 131 aa overlap and Mycobacterium tuberculosis Rv2445c SW:NDK_MYCTU (P71904) (136 aa), Fasta scores: E(): 0, 87.4% identity in 135 aa overlap. Contains Pfam match to entry PF00334 NDK, Nucleoside diphosphate kinases.;UniProt_AC=Q9CBZ0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1761568	1762671	.	-	0	Locus=ML1464c;Name=proB;Function=INVOLVED IN PROLINE BIOSYNTHESIS PATHWAY (AT THE FIRST STEP). CATALYZES THE TRANSFER OF A PHOSPHATE GROUP TO GLUTAMATE TO FORM GLUTAMATE 5-PHOSPHATE WHICH RAPIDLY CYCLIZES TO 5-OXOPROLINE [CATALYTIC ACTIVITY: ATP + L-GLUTAMATE = ADP + L-GLUTAMATE 5- PHOSPHATE].;Product=PROBABLE GLUTAMATE 5-KINASE PROTEIN PROB (GAMMA-GLUTAMYL KINASE) (GK);Comments=ML1464c, len: 367 aa.Probable proB, glutamate 5-kinase protein (GK) (EC 2.7.2.11). Highly similar to many glutamate 5-kinases involved in proline biosynthesis e.g. Escherichia coli SW:PROB_ECOLI (P07005) (367 aa), Fasta scores: E(): 0, 39.3% identity in 364 aa overlap and Mycobacterium tuberculosis Rv2439c SW:PROB_MYCTU (P71910) (376 aa), Fasta scores: E(): 0, 84.4% identity in 366 aa overlap. Contains Pfam match to entry PF00696 aakinase, Amino acid kinase family. Contains Pfam match to entry PF01472 PUA, PUA domain. Contains PS00902 Glutamate 5-kinase signature. BELONGS TO THE GLUTAMATE 5-KINASE FAMILY.;UniProt_AC=Q9CBZ5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1777926	1779439	.	-	0	Locus=ML1476c;Name=ML1476c;Function=;Product=Probable oxidoreductase alpha subunit (pseudogene);Comments=ML1476c, len: 1514 bp. Possible pseudogene of M. tuberculosis orthologue Rv2455c (1962 bp) (Best blastx scores: 483).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1785379	1786467	.	+	0	Locus=ML1482;Name=lipP;Function=;Product=Probable esterase/lipase LipP (pseudogene);Comments=ML1482, len: 1089 bp. Possible pseudogene of M. tuberculosis orthologue lipP|Rv2463 (1185 bp) (Best blastx scores: 423).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1786565	1787380	.	-	0	Locus=ML1483c;Name=ML1483c;Function=;Product=Possible DNA glycosylase (pseudogene);Comments=ML1483c, len: 816 bp. Possible pseudogene of M. tuberculosis orthologue Rv2464c (807 bp) (Best blastx scores: 234).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1792962	1794065	.	-	0	Locus=ML1488c;Name=ML1488c;Function=;Product=PROBABLE AMINOTRANSFERASE;Comments=ML1488c, len: 367 aa. Probable aminotransferase. Weakly similar to several putative aminotransferases including: Neisseria meningitidis TR:AAF41303 (EMBL:AE002441) (395 aa), Fasta scores: E(): 5.1e-13, 29.8% identity in 373 aa overlap and Mycobacterium tuberculosis Rv1178 TR:O50434 (EMBL:AL010186) (362 aa), Fasta scores: E(): 0, 83.4% identity in 361 aa overlap. Contains PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.;UniProt_AC=Q9CBX8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1808283	1808875	.	-	0	Locus=ML1500c;Name=narJ;Function=;Product=Probable respiratory nitrate reductase (delta chain) NarJ (pseudogene);Comments=ML1500c, len: 593 bp. Possible pseudogene of M. tuberculosis orthologue narJ|Rv1163 (606 bp) (Best blastx scores: 371).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1809062	1810604	.	-	0	Locus=ML1501c;Name=narH;Function=;Product=Probable respiratory nitrate reductase (beta chain) NarH (pseudogene);Comments=ML1501c, len: 1543 bp. Possible pseudogene of M. tuberculosis orthologue narH|Rv1162 (1677 bp) (Best blastx scores: 717).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1820852	1821192	.	-	0	Locus=ML1510c;Name=ML1510c;Function=;Product=Probable transcriptional regulatory protein (pseudogene);Comments=ML1510c, len: 341 bp. Possible pseudogene of M. tuberculosis orthologue Rv1152 (366 bp) (Best blastx scores: 173).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2888135	2889432	.	-	0	Locus=ML2416c;Name=gabP;Function=;Product=Probable 4-amino butyrate transporter GabP (pseudogene);Comments=ML2416c, len: 1298 bp. Possible pseudogene of M. tuberculosis orthologue gabP|Rv0522 (1305 bp) (Best blastx scores: 474).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1815095	1815379	.	+	0	Locus=ML1503A;Name=ML1503A;Function=;Product=conserved hypothetical protein;Comments=ML1503A, len: 94 aa. Conserved hypothetical protein,  orthologous to M. tuberculosis Rv1159A and similar to hypothetical proteins in Streptomyces coelicolor (SC5C7.25) and archaebacteria. FASTA scores: Rv1159A E(): 9e-33, 66/93 aa (70%) identical, and gp|AL03151 5AL031515|AL031515_25 Streptomyces coelicolor (101 aa) E(): 1.9e-06;  34.831% identity in 89 aa overlap;UniProt_AC=;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1887930	1889136	.	-	0	Locus=ML1563c;Name=cysG;Function=;Product=Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase, precorrin-2 oxidase and ferrochelatase (pseudogene);Comments=ML1563c, len: 1207 bp. Possible pseudogene of M. tuberculosis orthologue cysG|Rv2847c (1218 bp) (Best blastx scores: 286).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2744237	2744734	.	+	0	Locus=ML2316;Name=ML2316;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2316, len: 498 bp. Possible pseudogene of M. tuberculosis orthologue Rv3699 (702 bp) (Best blastx scores: 159).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1827781	1828791	.	-	0	Locus=ML1514A;Name=ML1514A;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1514A, len: 765 bp. Possible pseudogene similar to other hypothetical and efflux proteins e.g. Q82BT8 Hypothetical protein from Streptomyces avermitilis (Best blastx score: 229).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1829959	1831159	.	-	0	Locus=ML1516c;Name=hsdM;Function=;Product=Possible type I restriction/modification system DNA methylase HsdM (pseudogene);Comments=ML1516c, len: 1201 bp. Possible pseudogene of M. tuberculosis orthologue hsdM|Rv2756c (1623 bp) (Best blastx scores: 272).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1831358	1832332	.	-	0	Locus=ML1517c;Name=ML1517c;Function=;Product=hypothetical protein (pseudogene);Comments=ML1517c, len: 975 bp. Possible pseudogene, similar to several hypothetical proteins e.g. Q9HZZ9 Hypothetical protein PA2844 from Pseudomonas aeruginosa (402 aa) (Best blastx score: 161).;UniProt_AC=Q9CBW2;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1834922	1836705	.	-	0	Locus=ML1521c;Name=ML1521c;Function=;Product=Probable acyl-CoA dehydrogenase (pseudogene);Comments=ML1521c, len: 1784 bp. Possible pseudogene similar to several M. tuberculosis acyl-CoA dehydrogenases e.g fadE34|Rv3573c, fadE6|Rv0271, fadE33|Rv3564 etc (Best blastx scores: 108).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1838491	1839729	.	-	0	Locus=ML1524c;Name=ML1524c;Function=;Product=Probable fatty-acid-CoA synthetase (pseudogene);Comments=ML1524c, len: 1239 bp. Possible pseudogene similar to several M. tuberculosis fatty-acid-CoA ligases e.g fadD7|Rv0119, fadD35|Rv2505c, fadD13|Rv3089 etc (Best blastx scores: 127).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1837824	1838114	.	-	0	Locus=ML1523c;Name=ML1523c;Function=;Product=hypothetical protein;Comments=ML1523c, len: 96 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBV9;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1840015	1840470	.	-	0	Locus=ML1525c;Name=ML1525c;Function=;Product=conserved hypothetical protein;Comments=ML1525c, len: 151 aa. Conserved hypothetical protein. Similar to hypothetical proteins from Streptomyces coelicolor TR:Q9RD46 (EMBL:AL133424) (151 aa), Fasta scores: E(): 1.3e-28, 56.1% identity in 148 aa overlap and Mycobacterium tuberculosis Rv2771c TR:O33313 (EMBL:AL008967) (150 aa), Fasta scores: E(): 2.2e-26, 52.7% identity in 148 aa overlap.;UniProt_AC=Q9CBV8;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2829422	2831174	.	+	0	Locus=ML2364;Name=ML2364;Function=;Product=Possible hydrolase (pseudogene);Comments=ML2364, len: 1753 bp. Possible pseudogene of M. tuberculosis orthologue Rv3762c (1881 bp) (Best blastx scores: 368).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2833554	2834580	.	+	0	Locus=ML2365;Name=fadE36;Function=;Product=Possible acyl-CoA dehydrogenase FadE36 (pseudogene);Comments=ML2365, len: 1027 bp. Possible pseudogene of M. tuberculosis orthologue fadE36|Rv3761c (1056 bp) (Best blastx scores: 427).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1554169	1555686	.	-	0	Locus=ML1305c;Name=ansP2;Function=;Product=POSSIBLE L-ASPARAGINE PERMEASE ANSP2 (L-ASPARAGINE TRANSPORT PROTEIN);Comments=ML1305c, len: 505 aa. Probable ansP2, L-asparagine permease. Highly similar to many L-asparagine transport proteins including: Salmonella typhimurium AnsP SW:ANSP_SALTY (P40812) (497 aa), Fasta scores: E(): 0, 58.9% identity in 477 aa overlap and Mycobacterium tuberculosis Rv2127 SW:ANSP_MYCTU (O33261) (489 aa), Fasta scores: E(): 0, 83.7% identity in 485 aa overlap and O06297|Rv0346c Possible ansP2, L-asparagine permease (487 aa), fasta scores: E(): 1.8e-129, (69.76% identity in 473 aa overlap). Almost identical to the duplicated sequence ML1304. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00324 aa_permeases, Amino acid permease. Contains PS00218 Amino acid permeases signature.;UniProt_AC=Q9S379;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1874332	1875433	.	+	0	Locus=ML1550;Name=ML1550;Function=;Product=Possible hydrolase (pseudogene);Comments=ML1550, len: 1102 bp. Possible pseudogene of M. tuberculosis orthologue Rv2800 (1650 bp) (Best blastx scores: 259).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1878744	1879700	.	-	0	Locus=ML1554c;Name=ML1554c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1554c, len: 957 bp. Possible pseudogene of M. tuberculosis orthologue Rv2837c (1011 bp) (Best blastx scores: 178).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2835136	2835920	.	+	0	Locus=ML2367;Name=proX;Function=;Product=Possible osmoprotectant binding lipoprotein ProX (pseudogene);Comments=ML2367, len: 785 bp. Possible pseudogene of M. tuberculosis orthologue proX|Rv3759c (948 bp) (Best blastx scores: 216).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1654204	1655436	.	+	0	Locus=ML1383;Name=coaE;Function=;Product=Probable dephospho-CoA kinase CoaE (dephosphocoenzyme A kinase);Comments=ML1383, len: 410 aa. Probable coaE, dephospho-CoA kinase (EC 2.7.1.24). Highly similar to many  e.g. Mycobacterium tuberculosis Rv1631 SW:YG31_MYCTU (O06148) (407 aa), Fasta scores: E(): 0, 77.5% identity in 409 aa overlap and  Q9S2K7|COAE_STRCO Dephospho-CoA kinase from Streptomyces coelicolor  (200 aa), fasta scores: E(): 8e-32, (51.053% identity in 190 aa overlap). Contains Pfam match to entry PF01121 UPF0038, Uncharacterized protein family UPF0038. Contains PS01294 Uncharacterized protein family UPF0038 signature.;UniProt_AC=Q50178;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1549223	1550038	.	+	0	Locus=ML1301;Name=cysQ;Function=;Product=POSSIBLE MONOPHOSPHATASE CYSQ;Comments=ML1301, len: 271 aa. POssible cysQ, monophosphatase. Similar to several inositol monophosphatase family proteins including: Escherichia coli CysQ SW:CYSQ_ECOLI (P22255) (246 aa), Fasta scores: E(): 9.6e-07, 31.3% identity in 217 aa overlap and Mycobacterium tuberculosis CysQ protein homolog Rv2131c SW:CYSQ_MYCTU (O06244) (267 aa), Fasta scores: E(): 0, 76.0% identity in 271 aa overlap. Contains Pfam match to entry PF00459 inositol_P, Inositol monophosphatase family. Contains PS00629 Inositol monophosphatase family signature 1. Belongs to the inositol monophosphatase family.;UniProt_AC=P46726;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2842071	2842467	.	-	0	Locus=ML2374c;Name=ML2374c;Function=;Product=Possible integral membrane c-type cytochrome biogenesis protein (pseudogene);Comments=ML2374c, len: 397 bp. Possible pseudogene similar to M. tuberculosis Rv2874|dipZ (2088 bp) (Best blastx scores: 141).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1562248	1563117	.	+	0	Locus=ML1310;Name=hisG;Function=;Product=Probable ATP phosphoribosyltransferase HisG;Comments=ML1310, len: 289 aa. Probable hisG, ATP phosphoribosyltransferase (EC 2.4.2.17). Highly similar to many ATP phosphoribosyltransferases involved in histidine biosynthesis, including: Sulfolobus solfataricus HisG SW:HIS1_SULSO (O33771) (290 aa), Fasta scores: E(): 4e-20, 32.0% identity in 291 aa overlap and Mycobacterium tuberculosis Rv2121c SW:HIS1_MYCTU (O33256) (284 aa), Fasta scores: E(): 0, 87.8% identity in 287 aa overlap. Contains Pfam match to entry PF01503 PRA-PH, Phosphoribosyl-ATP pyrophosphohydrolase. Contains Pfam match to entry PF01634 HisG, ATP phosphoribosyltransferase. Contains PS01316 ATP phosphoribosyltransferase signature.;UniProt_AC=Q49776;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2530694	2530855	.	-	0	Locus=ML2129c;Name=ML2129c;Function=;Product=PE-family protein (pseudogene);Comments=ML2129c, len: 53 aa. Possible pseudogene similar to Mycobacterium tuberculosis PE-family protein O53690|AL021930 fasta scores: E(): 1.6e-05, 60.7% in 56 aa. most similar to PE29, PE5 and PE15;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2535359	2535797	.	+	0	Locus=ML2133;Name=ML2133;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2133, len: 439 bp. Possible pseudogene of M. tuberculosis orthologue Rv0887c (459 bp) (Best blastx scores: 221).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2836546	2836768	.	-	0	Locus=ML2368c;Name=ML2368c;Function=;Product=Probable transposase (pseudogene);Comments=ML2368c, len: 223 bp. Possible pseudogene similar to M. tuberculosis Rv3798 (1335 bp) (Best blastx scores: 52).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2842603	2844885	.	-	0	Locus=ML2375c;Name=ML2375c;Function=;Product=Probable conserved transmembrane transport protein (pseudogene);Comments=ML2375c, len: 2283 bp. Possible pseudogene similar to M. tuberculosis mmpL4|Rv0450c (2904 bp) (Best blastx scores: 1169), a orthologue of mmpL4 exist just upstream in M. leprae at ML2378.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1746891	1747565	.	-	0	Locus=ML1452c;Name=ML1452c;Function=;Product=PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE);Comments=ML1452c, len: 224 aa. Probable phosphoglycerate mutase (EC 5.4.2.1). Similar to several including: Mycobacterium tuberculosis Rv2419c TR:P71724 (EMBL:Z81368) (223 aa), Fasta scores: E(): 0, 80.4% identity in 224 aa overlap. Contains Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase family. Contains PS00175 Phosphoglycerate mutase family phosphohistidine signature. BELONGS TO THE PHOSPHOGLYCERATE MUTASE FAMILY.;UniProt_AC=Q9CC00;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1682090	1684600	.	+	0	Locus=ML1402;Name=pheT;Function=;Product=Probable phenylalanyl-tRNA synthetase, beta chain PheT;Comments=ML1402, len: 836 aa. Probable pheT, phenylalanyl-tRNA synthetase, beta chain (EC 6.1.1.20). Highly similar to many phenylalanyl-tRNA synthetase beta chains including: Escherichia coli SW:SYFB_ECOLI (P07395) (795 aa), Fasta scores: E(): 0, 31.0% identity in 851 aa overlap and Mycobacterium tuberculosis Rv1650|P94985|SYFB_MYCTU Phenylalanyl-tRNA synthetase beta (831 aa), fasta scores: E(): 0, (79.616% identity in 834 aa overlap). ;UniProt_AC=Q9CC16;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2928934	2929334	.	-	0	Locus=ML2455c;Name=ML2455c;Function=;Product=Probable transcriptional regulatory protein (pseudogene);Comments=ML2455c, len: 401 bp. Possible pseudogene of M. tuberculosis orthologue Rv0474 (423 bp) (Best blastx scores: 189).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1618919	1619854	.	+	0	Locus=ML1359;Name=ppnK;Function=;Product=Inorganic polyphosphate/ATP-NAD kinase PpnK (Poly(P)/ATP NAD kinase);Comments=ML1359, len: 311 aa. Probable ppnK, Inorganic polyphosphate/ATP-NAD kinase (EC 2.7.1.23). Similar to many others including: Streptomyces coelicolor TR:Q9S219 (EMBL:AL109848) (301 aa), Fasta scores: E(): 0, 54.5% identity in 303 aa overlap and Mycobacterium tuberculosis Rv1695 SW:YG95_MYCTU (O33196) (307 aa), Fasta scores: E(): 0, 87.9% identity in 305 aa overlap. Contains Pfam match to entry PF01513 DUF15, Domain of unknown function.;UniProt_AC=Q49897;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1532567	1533761	.	-	0	Locus=ML1287c;Name=ML1287c;Function=;Product=Probable nonspecific lipid-transfer protein (pseudogene);Comments=ML1287c, len: 1194 bp. Possible pseudogene of M. tuberculosis orthologue Rv1627c (1209 bp) (Best blastx scores: 235).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1843931	1844865	.	-	0	Locus=ML1529c;Name=ML1529c;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML1529c, len: 935 bp. Possible pseudogene of M. tuberculosis orthologue Rv2776c (930 bp) (Best blastx scores: 445). Also similar to ML1758c possible pseudogene similar to M. tuberculosis Rv2776c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1860616	1860789	.	-	0	Locus=ML1541c;Name=ML1541c;Function=;Product=Probable ferredoxin (pseudogene);Comments=ML1541c, len: 174 bp. Possible pseudogene of M. tuberculosis orthologue Rv1786 (204 bp0 (Best blastx scores: 147).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1861016	1862166	.	+	0	Locus=ML1542;Name=cyp143;Function=;Product=Probable cytochrome P450 Cyp143 (pseudogene);Comments=ML1542, len: 1151 bp. Possible pseudogene of M. tuberculosis orthologue Rv1785c|cyp143 (1182 bp) (Best blastx scores: 322).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1842581	1843888	.	+	0	Locus=ML1528;Name=ML1528;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1528, len: 1308 bp. Possible pseudogene similar to several M. tuberculosis proteins in REP13E12 repeats e.g. Rv1128, Rv1148 and Rv1945 (Best blastx scores: 194).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1845381	1846353	.	-	0	Locus=ML1530c;Name=ML1530c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1530c, len: 973 bp. Possible pseudogene of M. tuberculosis orthologue Rv2777c (1071 bp) (Best blastx scores: 581).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1846363	1846797	.	-	0	Locus=ML1531c;Name=ML1531c;Function=;Product=Possible transcriptional regulatory protein (Lrp/AsnC family) (pseudogene);Comments=ML1531c, len: 435 bp. Possible pseudogene of M. tuberculosis orthologue Rv2779c (540 bp) (Best blastx scores: 211).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1840963	1841694	.	-	0	Locus=ML1527c;Name=dapB;Function=;Product=Dihydrodipicolinate reductase DapB (pseudogene);Comments=ML1527c, len: 731 bp. Possible pseudogene of M. tuberculosis orthologue dapB|Rv2773c (738 bp) (Best blastx scores: 605).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1892390	1893863	.	-	0	Locus=ML1568c;Name=mqo;Function=;Product=Probable malate:quinone oxidoreductase Mqo (pseudogene);Comments=ML1568c, len: 1474 bp. Possible pseudogene of M. tuberculosis orthologue Rv2852c|mqo (1482 bp) (Best blastx scores: 535).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1894014	1894986	.	+	0	Locus=ML1569;Name=ML1569;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1569, len: 973 bp. Possible pseudogene of M. tuberculosis orthologue Rv2854 (1041 bp) (Best blastx scores: 330).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1895087	1896443	.	+	0	Locus=ML1570;Name=mtr;Function=;Product=NADPH-dependent mycothiol reductase Mtr (pseudogene);Comments=ML1570, len: 1357 bp. Possible pseudogene of M. tuberculosis orthologue mtr|Rv2855 (1380 bp) (Best blastx scores: 595) but previously described as glutathione reductase homolog (gene name: gorA).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1873756	1874284	.	+	0	Locus=ML1549;Name=ML1549;Function=;Product=Probable membrane protein (pseudogene);Comments=ML1549, len: 529 bp. Possible pseudogene of M. tuberculosis orthologue Rv2799 (630 bp) (Best blastx scores: 220).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1770444	1773104	.	-	0	Locus=ML1472c;Name=valS;Function=;Product=PROBABLE VALYL-tRNA SYNTHASE PROTEIN VALS (VALYL-tRNA SYNTHETASE) (VALINE--tRNA LIGASE) (VALINE TRANSLASE) ELONGS TO CLASS-I AMINOACYL-TRNA SYNTHETASE FAMILY.;Comments=ML1472c, len: 886 aa. Probable valS, valyl-tRNA synthase (EC 6.1.1.9). Highly similar to many valyl-tRNA synthetases including: Bacillus stearothermophilus SW:SYV_BACST (P11931) (880 aa), Fasta scores: E(): 0, 46.6% identity in 894 aa overlap and Mycobacterium tuberculosis Rv2448c SW:SYV_MYCTU (O53175) (876 aa), Fasta scores: E(): 0, 85.4% identity in 876 aa overlap. Contains Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature.;UniProt_AC=Q9CBY7;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1891169	1892064	.	-	0	Locus=ML1566c;Name=ML1566c;Function=;Product=Possible magnesium-chelatase (pseudogene);Comments=ML1566c, len: 896 bp. Possible pseudogene of M. tuberculosis orthologue Rv2850c (1890 bp) (Best blastx scores: 295).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1892069	1892381	.	-	0	Locus=ML1567c;Name=ML1567c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1567c, len: 313 bp. Possible pseudogene of M. tuberculosis orthologue Rv2851c (471 bp) (Best blastx scores: 221).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1890870	1891101	.	-	0	Locus=ML1565c;Name=cobO;Function=;Product=Probable cob(I)alamin adenosyltransferase CobO (pseudogene);Comments=ML1565c, len: 232 bp. Possible pseudogene of M. tuberculosis orthologue cobO|Rv2849c (624 bp) (Best blastx scores: 168).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1899803	1900060	.	-	0	Locus=ML1574c;Name=glnA4;Function=;Product=Proable glutamine synthetase GlnA4 (pseudogene);Comments=ML1574c, len: 258 bp. Possible pseudogene of M. tuberculosis orthologue glnA4|Rv2860c (1374 bp) (Best blastx scores: 129).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1920498	1920913	.	+	0	Locus=ML1595;Name=ML1595;Function=;Product=Probable transcriptional regulatory protein (pseudogene);Comments=ML1595, len: 416 bp. Possible pseudogene of M. tuberculosis orthologue Rv2887 (420 bp) (Best blastx scores: 208).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2031714	2032421	.	+	0	Locus=ML1686;Name=ML1686;Function=;Product=Probable transcriptional regulatory protein (IclR family) (pseudogene);Comments=ML1686, len: 708 bp. Possible pseudogene of M. tuberculosis orthologue Rv2989 (702 bp) (Best blastx scores: 788).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2062149	2062849	.	-	0	Locus=ML1709c;Name=ML1709c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1709c, len: 701 bp. Possible pseudogene of M. tuberculosis orthologue Rv3026c (915 bp) (Best blastx scores: 316).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1851131	1851441	.	+	0	Locus=ML1535;Name=ML1535;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1535, len: 311 bp. Possible pseudogene of M. tuberculosis orthologue Rv1805c (348 bp) (Best blastx scores: 106). Also similar to ML2668 a possible pseudogene similar to M. tuberculosis Rv1805c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1876266	1876993	.	+	0	Locus=ML1552;Name=echA16;Function=;Product=Probable enoyl-CoA hydratase EchA16 (pseudogene);Comments=ML1552, len: 728 bp. Possible pseudogene of M. tuberculosis orthologue echA16|Rv2831 (Best blastx scores: 202);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2696143	2697235	.	+	0	Locus=ML2272;Name=pimB;Function=;Product=Mannosyltransferase PimB (pseudogene);Comments=ML2272, len: 1093 bp. Possible pseudogene of M. tuberculosis orthologue Rv0557|pimB (1137 bp) (Best blastx scores: 351).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2113897	2114511	.	-	0	Locus=ML1749c;Name=ML1749c;Function=;Product=Putative transposase (pseudogene);Comments=ML1749c, len: 615 bp. Possible pseudogene similar to M. smegmatis putative IS1549 transposase (Best blastx scores: 144).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1883022	1883342	.	-	0	Locus=ML1557c;Name=ML1557c;Function=;Product=conserved hypothetical protein;Comments=ML1557c, len: 106 aa. Conserved hypothetical protein. Highly similar to several proteins of undefined function including: Mycobacterium tuberculosis Rv2840c TR:P71612 (EMBL:Z81331) (99 aa), Fasta scores: E(): 1.7e-30, 81.3% identity in 96 aa overlap.;UniProt_AC=Q9Z5J0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1858301	1859203	.	-	0	Locus=ML1540c;Name=ML1540c;Function=;Product=conserved hypothetical protein;Comments=ML1540c, len: 300 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1794 TR:O53943 (EMBL:AL022021) (300 aa), Fasta scores: E(): 0, 88.0% identity in 300 aa overlap.;UniProt_AC=Q9Z5I1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2433036	2433623	.	+	0	Locus=ML2042;Name=ahpC;Function=;Product=ALKYL HYDROPEROXIDE REDUCTASE C PROTEIN AHPC (ALKYL HYDROPEROXIDASE C);Comments=ML2042, len: 195 aa. Probable ahpC, alkyl hydroperoxide reductase (EC 1.-.-.-). Similar to several e.g. Mycobacterium avium TR:Q57413 (EMBL:U18263) fasta scores: E(): 0, 86.2% in 195 aa, and to Streptomyces viridosporus  TR:Q9X5V0 (EMBL:AF127576) fasta scores: E(): 0, 58.7% in 189 aa and Q57348 Rv2428 M. tuberculosis (195 aa), fasta scores: E(): 1.6e-75, (86.667% identity in 195 aa overlap). Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family.;UniProt_AC=Q9CBF5;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1884588	1885117	.	-	0	Locus=ML1559c;Name=ML1559c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1559c, len: 530 bp. Possible pseudogene of M. tuberculosis orthologue Rv2842c (552 bp) (Best blastx scores: 293).;UniProt_AC=Q9Z5J2;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1889194	1890521	.	-	0	Locus=ML1564c;Name=cobB;Function=;Product=Probable cobyrinic acid a,c-diamide synthase CobB (pseudogene);Comments=ML1564c, len: 1328 bp. Possible pseudogene of M. tuberculosis orthologue cobB|Rv2848c (Best blastx scores: 390).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1896813	1897745	.	+	0	Locus=ML1571;Name=nicT;Function=;Product=Probable nickel transport integral membrane protein NicT (pseudogene);Comments=ML1571, len: 933 bp. Possible pseudogene of M. tuberculosis orthologue nicT|Rv2856 (1119 bp) (Best blastx scores: 614).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1904954	1905684	.	-	0	Locus=ML1580c;Name=ML1580c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1580c, len: 731 bp. Possible pseudogene of M. tuberculosis orthologue Rv2867c (855 bp) (Best blastx scores: 382).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2201937	2202294	.	-	0	Locus=ML1819c;Name=ctpD;Function=;Product=Probable cation transporter P-type ATPase D CtpD (pseudogene);Comments=ML1819c, len: 358 bp. Possible pseudogene of M. tuberculosis orthologue Rv1469|ctpD (1974 bp) (Best blastx scores: 206).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1885245	1885781	.	+	0	Locus=ML1560;Name=ML1560;Function=;Product=conserved hypothetical protein;Comments=ML1560, len: 178 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2843 TR:O05816 (EMBL:Z95207) (181 aa), Fasta scores: E(): 2e-31, 70.2% identity in 168 aa overlap.;UniProt_AC=Q9Z5J3;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1898130	1898528	.	+	0	Locus=ML1572;Name=ML1572;Function=;Product=hypothetical protein;Comments=ML1572, len: 132 aa. Hypothetical unknown protein, some similarity to O50518 Hypothetical protein SCO5844 from Streptomyces coelicolor (397 aa), fasta scores: E(): 8.1e-07, (35.135% identity  in 111 aa overlap);UniProt_AC=Q9CBV0;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1900175	1900468	.	-	0	Locus=ML1575c;Name=ML1575c;Function=;Product=hypothetical protein;Comments=ML1575c, len: 97 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBU8;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1885778	1886275	.	+	0	Locus=ML1561;Name=ML1561;Function=;Product=conserved hypothetical protein;Comments=ML1561, len: 165 aa. Conserved hypothetical protein. Highly similar to proteins of unknown function from Streptomyces coelicolor TR:CAB91137 (EMBL:AL355913) (167 aa), Fasta scores: E(): 1.4e-07, 35.8% identity in 137 aa overlap and Mycobacterium tuberculosis Rv2844 SW:O05815 (162 aa), fasta scores: E(): 6.2e-46, (71.515% identity in 165 aa overlap).;UniProt_AC=Q9Z5J4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1911381	1912181	.	-	0	Locus=ML1585c;Name=ML1585c;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML1585c, len: 801 bp. Possible pseudogene of M. tuberculosis orthologue Rv2877c (864 bp) (Best blastx scores: 174).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1912800	1913349	.	-	0	Locus=ML1587c;Name=ML1587c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1587c, len: 550 bp. Possible pseudogene of M. tuberculosis orthologue Rv2879c (570 bp) (Best blastx scores: 272);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1932278	1932601	.	-	0	Locus=ML1606c;Name=ML1606c;Function=;Product=conserved hypothetical protein (pseudogene);Comments=ML1606c, len: 324 bp. Possible pseudogene of M. tuberculosis orthologue Rv2897c (1512 bp) (Best blastx scores: 361).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1933139	1933670	.	-	0	Locus=ML1608c;Name=fdhD;Function=;Product=Possible FdhD protein (pseudogene);Comments=ML1608c, len: 532 bp. Possible pseudogene of M. tuberculosis orthologue fdhD|Rv2899c (831 bp) (Best blastx scores: 188).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1952203	1953304	.	-	0	Locus=ML1627c;Name=amt;Function=;Product=Probable ammonium transport integral membrane protein Amt (pseudogene);Comments=ML1627c, len: 1102 bp. Possible pseudogene of M. tuberculosis orthologue amt|Rv2920c (Best blastx scores: 233);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1970380	1971820	.	+	0	Locus=ML1636;Name=ML1636;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1636, len: 1441 bp. Possible pseudogene of M. tuberculosis orthologue Rv2226 (1542 bp) (Best blastx scores: 294).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2128430	2128798	.	+	0	Locus=ML1754;Name=ML1754;Function=;Product=PPE-family protein (pseudogene);Comments=ML1754, len: 369 bp. Possible pseudogene similar to numerous M. tuberculosis PPE-family proteins e.g. PPE19|Rv1361c, PPE2|Rv0256c, PPE48|Rv3022c, PPE11|Rv0453 and PPE37|Rv2123 (Best blastx scores: 134).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2197988	2198544	.	+	0	Locus=ML1815;Name=ML1815;Function=;Product=Probable transcriptional regulatory protein (TetR/AcrR family) (pseudogene);Comments=ML1815, len: 557 bp. Possible pseudogene of M. tuberculosis orthologue Rv1474c (564 bp) (Best blastx scores: 442).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2301184	2301801	.	+	0	Locus=ML1917;Name=ML1917;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1917, len: 618 bp. Possible pseudogene of M. tuberculosis orthologue Rv3586 (1077 bp) (Best blastx scores: 150).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2395011	2395792	.	+	0	Locus=ML2002;Name=fadB5;Function=;Product=Possible oxidoreductase FadB5 (pseudogene);Comments=ML2002, len: 782 bp. Possible pseudogene of M. tuberculosis orthologue fadB5|Rv1912c (1005 bp) (Best blastx scores: 327).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1988391	1989203	.	-	0	Locus=ML1650c;Name=ML1650c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1650c, len: 813 bp. Possible pseudogene of M. tuberculosis orthologue Rv2240c (Best blastx scores: 203).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2873825	2875117	.	+	0	Locus=ML2403;Name=ML2403;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2403, len: 1293 bp. Possible pseudogene of M. tuberculosis orthologue Rv1069c (1764 bp) (Best blastx scores: 333).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1931213	1931413	.	+	0	Locus=ML1605;Name=ML1605;Function=;Product=hypothetical protein;Comments=ML1605, len: 66 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBT6;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2363941	2364348	.	-	0	Locus=ML1979c;Name=ML1979c;Function=;Product=hypothetical protein;Comments=ML1979c, len: 135 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBH3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1909596	1909850	.	+	0	Locus=ML1584;Name=ML1584;Function=;Product=POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML1584, len: 84 aa. Possible conserved transmembrane protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2876 SW:YS76_MYCTU (Q10802) (104 aa), Fasta scores: E(): 3.3e-26, 75.0% identity in 88 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CBU2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1949524	1951565	.	-	0	Locus=ML1625c;Name=glnD;Function=;Product=Probable uridylyltransferase GlnD (pseudogene);Comments=ML1625c, len: 2042 bp. Possible pseudogene of M. tuberculosis orthologue glnD|Rv2918c (2427 bp) (Best blastx scores: 428).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1951869	1952203	.	-	0	Locus=ML1626c;Name=glnB;Function=;Product=Probable nitrogen regulatory protein GlnB (pseudogene);Comments=ML1626c, len: 335 bp. Possible pseudogene of M. tuberculosis orthologue glnB|Rv2919c (339 bp) (Best blastx scores: 227).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2055050	2055748	.	+	0	Locus=ML1704;Name=ML1704;Function=;Product=conserved hypothetical protein;Comments=ML1704, len: 232 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv3013 TR:O53260 (EMBL:AL021287) (218 aa), Fasta scores: E(): 0, 84.3% identity in 216 aa overlap.;UniProt_AC=Q9CBR7;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1926761	1927126	.	-	0	Locus=ML1601c;Name=ML1601c;Function=;Product=hypothetical protein;Comments=ML1601c, len: 121 aa. Hypothetical unknown protein.;UniProt_AC=O33034;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2200636	2201457	.	-	0	Locus=ML1817c;Name=ML1817c;Function=;Product=Possible enoyl-CoA hydratase EchA12 (pseudogene);Comments=ML1817c, len: 822 bp. Possible pseudogene similar to M. tuberculosis echA12|Rv1472 (858 bp) (Best blastx scores: 581), also similar to ML1241 a possible orthologue of M. tuberculosis echA12 .;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2207111	2208633	.	-	0	Locus=ML1823c;Name=ML1823c;Function=;Product=Putative transposase (pseudogene);Comments=ML1823c, len: 1523 bp. Possible pseudogene similar to M. smegmatis putative IS1549 transposase (1509 bp) (Best blastx scores: 393).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2372747	2373198	.	-	0	Locus=ML1986c;Name=ML1986c;Function=;Product=Probable RNA polymerase sigma factor, ECF subfamily (pseudogene);Comments=ML1986c, len: 452 bp. Possible pseudogene similar to M. tuberculosis sigC|Rv2069 (558 bp) (Best blastx scores: 104). Also similar to ML1448 a possible orthologue of M. tuberculosis sigC.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2393663	2394285	.	-	0	Locus=ML2001c;Name=ML2001c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2001c, len: 623 bp. Possible pseudogene of M. tuberculosis orthologue Rv1913 (753 bp) (Best blastx scores: 204).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2430745	2431199	.	-	0	Locus=ML2039c;Name=ML2039c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2039c, len: 455 bp. Possible pseudogene of M. tuberculosis orthologue Rv1875 (444 bp) (Best blastx scores: 120).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2533963	2535008	.	+	0	Locus=ML2132;Name=citA;Function=;Product=Probable citrate synthase II CitA (pseudogene);Comments=ML2132, len: 1046 bp. Possible pseudogene of M. tuberculosis orthologue citA|Rv0889c (1122 bp) (Best blastx scores: 650).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2685660	2686473	.	-	0	Locus=ML2262c;Name=ML2262c;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML2262c, len: 814 bp. Possible pseudogene of M. tuberculosis orthologue Rv0547c (885 bp) (Best blastx scores: 587).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2745528	2745656	.	-	0	Locus=ML2318c;Name=ML2318c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2318c, len: 129 bp. Possible pseudogene of M. tuberculosis orthologue Rv3703c (1278 bp) (Best blastx scores: 169).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2756639	2757602	.	-	0	Locus=ML2325c;Name=dnaQ;Function=;Product=Probable DNA polymerase III (epsilon chain) DnaQ (pseudogene);Comments=ML2325c, len: 964 bp. Possible pseudogene of M. tuberculosis orthologue dnaQ|Rv3711c (990 bp) (Best blastx scores: 453).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2775372	2778525	.	+	0	Locus=ML2340;Name=ML2340;Function=;Product=Probable conserved two-domain membrane protein (pseudogene);Comments=ML2340, len: 3154 bp. Possible pseudogene of M. tuberculosis orthologue Rv3728 (3198 bp) (Best blastx scores: 386).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2841568	2842047	.	-	0	Locus=ML2373c;Name=ML2373c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2373c, len: 480 bp. Possible pseudogene of M. tuberculosis orthologue Rv0448c (666 bp) (Best blastx scores: 183).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2233459	2234455	.	-	0	Locus=ML1850c;Name=ML1850c;Function=;Product=Conserved 13E12 repeat family protein (pseudogene);Comments=ML1850c, len: 997 bp. Possible pseudogene similar to M. tuberculosis 13E12 repeat family e.g. Rv0336 or Rv0515 (Best blastx scores: 237), similar to M. leprae ML1290 pseudogene.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2309713	2310733	.	-	0	Locus=ML1924c;Name=ML1924c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1924c, len: 1021 bp. Possible pseudogene of M. tuberculosis orthologue Rv0433 (1131 bp) (Best blastx scores: 802).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2745752	2746966	.	-	0	Locus=ML2319c;Name=gshA;Function=;Product=Possible glutamate--cysteine ligase GshA (pseudogene);Comments=ML2319c, len: 1215 bp. Possible pseudogene of M. tuberculosis orthologue gshA|Rv3704c (1299 bp) (Best blastx scores: 360).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1933739	1934811	.	-	0	Locus=ML1609c;Name=fdhF;Function=;Product=Possible formate dehydrogenase FdhF (pseudogene);Comments=ML1609c, len: 1073 bp. Possible pseudogene of M. tuberculosis orthologue fdhF|Rv2900c (2340 bp) (Best blastx scores: 351).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2039929	2041173	.	+	0	Locus=ML1693;Name=ML1693;Function=;Product=Possible alanine rich dehydrogenase (pseudogene);Comments=ML1693, len: 1245 bp. Possible pseudogene of M. tuberculosis orthologue Rv2997 (1443 bp) (Best blastx scores: 314).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1967676	1968964	.	-	0	Locus=ML1634c;Name=ML1634c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1634c, len: 1289 bp. Possible pseudogene similar to several M. tuberculosis conserved hypothetical proteins e.g. Rv1760, Rv0895 and Rv1425 (Best blastx scores: 229).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2912936	2914369	.	+	0	Locus=ML2438;Name=ML2438;Function=;Product=Probable oxidoreductase GMC type (pseudogene);Comments=ML2438, len: 1434 bp. Possible pseudogene of M. tuberculosis orthologue Rv0492c (1890 bp) (Best blastx scores: 274).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3076868	3077081	.	-	0	Locus=ML2577c;Name=ML2577c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2577c, len: 214 bp. Possible pseudogene of M. tuberculosis orthologue Rv1103c (321 bp) (Best blastx scores: 91).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2070057	2071120	.	+	0	Locus=ML1716;Name=ML1716;Function=;Product=Probable membrane protein (pseudogene);Comments=ML1716, len: 1064 bp. Possible pseudogene similar to M. tuberculosis Rv1490 (1308 bp) (Best blastx scores: 164).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2071291	2071638	.	+	0	Locus=ML1717;Name=ML1717;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1717, len: 348 bp. Possible pseudogene similar to Q8VJ84 Hypothetical protein MT3117 from M. tuberculosis CDC1551 (387 bp) (best blastx score: 260).;UniProt_AC=Q9CBR2;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2081624	2082464	.	-	0	Locus=ML1725c;Name=ML1725c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1725c, len: 841 bp. Possible pseudogene of M. tuberculosis orthologue Rv3040c (867 bp) (Best blastx scores: 838).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2105023	2105675	.	-	0	Locus=ML1744c;Name=ML1744c;Function=;Product=Probable transcriptional regulatory protein (GntR family) (pseudogene);Comments=ML1744c, len: 653 bp. Possible pseudogene of M. tuberculosis orthologue Rv3060c (1473 bp) (Best blastx scores: 270).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2865047	2865796	.	-	0	Locus=ML2395c;Name=pra;Function=;Product=Probable Proline-rich antigen homolog Pra;Comments=ML2395c, len: 249 aa. Probable pra, Proline-rich antigen homolog. Previously characterised Mycobacterium leprae proline-rich antigen Ag36 SW:PRA_MYCLE (P41484) (249 aa) fasta scores: E(): 0, 99.2% identity in 249 aa. Note the N-terminus of this protein is extremely rich in the amino acid Pro and contains a 3xGGSYPPPPP repeats. Contains possible membrane spanning hydrophobic domains. Previously known as Ag36.;UniProt_AC=P41484;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1940003	1940245	.	-	0	Locus=ML1617c;Name=ML1617c;Function=;Product=conserved hypothetical protein;Comments=ML1617c, len: 80 aa. Conserved hypothetical protein. Highly similar to many proteins of undefined function e.g. Mycobacterium tuberculosis Rv2908c SW:YT08_MYCTU (Q10826) (80 aa), Fasta scores: E(): 6.5e-28, 93.8% identity in 80 aa overlap. Contains Pfam match to entry PF00013 KH-domain, KH domain.;UniProt_AC=O33015;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2296436	2297130	.	+	0	Locus=ML1913;Name=echA3;Function=;Product=Probable enoyl-CoA hydratase EchA3 (pseudogene);Comments=ML1913, len: 695 bp. Possible pseudogene of M. tuberculosis orthologue echA3|Rv0632c (696 bp) (Best blastx scores: 350).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2299923	2300397	.	+	0	Locus=ML1916;Name=ML1916;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1916, len: 475 bp. Possible pseudogene of M. tuberculosis orthologue Rv0580c (492 bp) (Best blastx scores: 335).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2368114	2369142	.	-	0	Locus=ML1984c;Name=ML1984c;Function=;Product=Possible monooxygenase (pseudogene);Comments=ML1984c, len: 1029 bp. Possible pseudogene similar to M. tuberculosis Rv3618 (1188 bp) (Best blastx scores: 108). Also similar to ML0220c a possible pseudogene similar to M. tuberculosis Rv3618.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2443630	2444722	.	-	0	Locus=ML2056c;Name=modC;Function=;Product=Probable molybdenum-transport ATP-binding protein ABC transporter ModC (pseudogene);Comments=ML2056c, len: 1093 bp. Possible pseudogene of M. tuberculosis orthologue modC|Rv1859 (1110 bp) (Best blastx scores: 272).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2493325	2494406	.	+	0	Locus=ML2097;Name=ML2097;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2097, len: 1082 bp. Possible pseudogene of M. tuberculosis orthologue Rv0926c (1077 bp) (Best blastx scores: 224).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2574012	2574275	.	-	0	Locus=ML2164c;Name=ML2164c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2164c, len: 264 bp. Possible pseudogene of M. tuberculosis orthologue Rv0857 (474 bp) (Best blastx scores: 152).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2140727	2141749	.	-	0	Locus=ML1766c;Name=ML1766c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1766c, len: 1023 bp. Possible pseudogene of M. tuberculosis orthologue Rv2314c (1374 bp) (Best blastx scores: 286).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2634538	2634781	.	-	0	Locus=ML2216c;Name=ML2216c;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML2216c, len: 244 bp. Possible pseudogene of M. tuberculosis orthologue Rv0794c (1500 bp) (Best blastx scores: 153).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2634761	2635293	.	+	0	Locus=ML2217;Name=ML2217;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2217, len: 533 bp. Possible pseudogene of M. tuberculosis orthologue Rv0790c (729 bp) (Best blastx scores: 295).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2635361	2635935	.	+	0	Locus=ML2218;Name=ML2218;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2218, len: 575 bp. Possible pseudogene of M. tuberculosis orthologue Rv0789c (600 bp) (Best blastx scores: 122).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2637059	2637296	.	-	0	Locus=ML2220c;Name=ML2220c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2220c, len: 238 bp. Possible pseudogene of M. tuberculosis orthologue Rv0787 (960 bp) (Best blastx scores: 111).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2705542	2706682	.	-	0	Locus=ML2281c;Name=ML2281c;Function=;Product=Probable monooxygenase (pseudogene);Comments=ML2281c, len: 1141 bp. Possible pseudogene of M. tuberculosis orthologue Rv0565c (1461 bp) (Best blastx scores: 482).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2825333	2825957	.	-	0	Locus=ML2360c;Name=ML2360c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2360c, len: 625 bp. Possible pseudogene of M. tuberculosis orthologue Rv3766 (690 bp) (Best blastx scores: 165).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2840038	2840641	.	-	0	Locus=ML2371c;Name=ML2371c;Function=;Product=Possible conserved transmembrane protein (pseudogene);Comments=ML2371c, len: 604 bp. Possible pseudogene of M. tuberculosis orthologue Rv0446c (771 bp) (Best blastx scores: 144).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2235755	2236036	.	-	0	Locus=ML1852c;Name=ML1852c;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML1852c, len: 282 bp. Possible pseudogene of M. tuberculosis orthologue Rv0713 (942 bp) (Best blastx scores: 194).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2712443	2712667	.	-	0	Locus=ML2288c;Name=ML2288c;Function=;Product=hypothetical protein;Comments=ML2288c, len: 74 aa. Hypothetical protein.;UniProt_AC=Q9CBA0;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2739928	2740518	.	+	0	Locus=ML2312;Name=ML2312;Function=;Product=POSSIBLE CONSERVED MEMBRANE PROTEIN;Comments=ML2312, len: 196 aa. Possible conserved membrane protein. Similar to the C-terminus of Mycobacterium tuberculosis hypothetical protein Rv3695 TR:O69663 (EMBL:AL022121) (310 aa) fasta scores: E(): 0, 71.1% identity in 190 aa and Streptomyces coelicolor putative integral membrane protein TR:CAB88905 (EMBL:AL353862) (318 aa) fasta scores: E(): 2e-15, 39.5% identity in 190 aa. Contains a possible membrane spanning hydrophobic domain;UniProt_AC=Q9CB83;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1924410	1924751	.	+	0	Locus=ML1599;Name=ML1599;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1599, len: 342 bp. Possible pseudogene of M. tuberculosis orthologue Rv2891 (750 bp) (Best blastx scores: 96).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1983846	1984139	.	-	0	Locus=ML1646c;Name=ML1646c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1646c, len: 294 bp. Possible pseudogene of M. tuberculosis orthologue Rv1045 (882 bp) (Best blastx scores: 116).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1984409	1984869	.	-	0	Locus=ML1647c;Name=ML1647c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1647c, len: 461 bp. Possible pseudogene of M. tuberculosis orthologue Rv1044 (624 bp) (Best blastx scores: 117).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1987392	1987836	.	-	0	Locus=ML1648c;Name=ahpE;Function=;Product=Probable peroxiredoxin AhpE (pseudogene);Comments=ML1648c, len: 445 bp. Possible pseudogene of M. tuberculosis orthologue ahpE|Rv2238c (462 bp) (Best blastx scores: 175).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2036005	2037307	.	+	0	Locus=ML1690;Name=ML1690;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML1690, len: 1303 bp. Possible pseudogene of M. tuberculosis orthologue Rv2994 (1338 bp) (Best blastx scores: 382).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2098940	2099948	.	+	0	Locus=ML1739;Name=dinP;Function=;Product=Probable DNA-damage-inducible protein DinP (pseudogene);Comments=ML1739, len: 1009 bp. Possible pseudogene of M. tuberculosis orthologue dinP|Rv3056 (1041 bp) (Best blastx scores: 362).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2100936	2101545	.	-	0	Locus=ML1741c;Name=ML1741c;Function=;Product=Possible transcriptional regulatory protein (pseudogene);Comments=ML1741c, len: 610 bp. Possible pseudogene of M. tuberculosis orthologue Rv3058c (651 bp) (Best blastx scores: 207).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2101770	2103145	.	+	0	Locus=ML1742;Name=cyp136;Function=;Product=Probable cytochrome P450 136 Cyp136 (pseudogene);Comments=ML1742, len: 1376 bp. Possible pseudogene of M. tuberculosis orthologue Rv3059|cyp136 (1479 bp) (Best blastx scores: 393).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2109665	2110134	.	+	0	Locus=ML1747;Name=ligB;Function=;Product=Probable ATP-dependent DNA ligase LigB (pseudogene);Comments=ML1747, len: 470 bp. Possible pseudogene of M. tuberculosis orthologue ligB|Rv3062 (1524 bp) (Best blastx scores: 120).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2216058	2216875	.	-	0	Locus=ML1830c;Name=ML1830c;Function=;Product=Probable histidinol-phosphate aminotransferase (pseudogene);Comments=ML1830c, len: 818 bp. Possible pseudogene similar to M. tuberculosis hisC2|Rv3772 (1062 bp) (Best blastx scores: 129) and other histidinol-phosphate aminotransferases. Also similar to ML0122c a possible pseudogene similar to M. tuberculosis hisC2.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2211844	2212480	.	-	0	Locus=ML1827c;Name=cobQ1;Function=;Product=Probable cobyric acid synthase CobQ1 (pseudogene);Comments=ML1827c, len: 637 bp. Possible pseudogene of M. tuberculosis orthologue cobQ1|Rv0255c (Best blastx scores: 336).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2163362	2163826	.	-	0	Locus=ML1788c;Name=ML1788c;Function=;Product=hypothetical protein;Comments=ML1788c, len: 154 aa. Hypothetical unknown protein (questionable CDS).;UniProt_AC=Q7AQ24;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2169020	2169325	.	+	0	Locus=ML1793;Name=ML1793;Function=;Product=hypothetical protein;Comments=ML1793, len: 101 aa. Hypothetical unknown protein. Some similarity to other hypothetical proteins e.g. Q9I5F1 Hypothetical protein PA0787 from Pseudomonas aeruginosa (387 aa), fasta scores:  E(): 2.1e-06, (41.237% identity in 97 aa overlap).;UniProt_AC=Q9CBN0;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2517659	2518643	.	-	0	Locus=ML2117c;Name=ML2117c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2117c, len: 291 bp. Possible pseudogene of M. tuberculosis orthologue Rv0906 (1119 bp) (Best blastx scores: 599).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2596788	2597130	.	+	0	Locus=ML2182;Name=ML2182;Function=;Product=Probable transcriptional regulatory protein (ArsR family) (pseudogene);Comments=ML2182, len: 343 bp. Possible pseudogene of M. tuberculosis orthologue Rv0827c (393 bp) (Best blastx scores: 201).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2597279	2598303	.	-	0	Locus=ML2183c;Name=ML2183c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2183c, len: 1025 bp. Possible pseudogene of M. tuberculosis orthologue Rv0826 (1056 bp) (Best blastx scores: 263).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2649027	2649792	.	+	0	Locus=ML2231;Name=ML2231;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2231, len: 766 bp. Possible pseudogene of M. tuberculosis orthologue Rv0776c (780 bp) (Best blastx scores: 364).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2704488	2705474	.	-	0	Locus=ML2280c;Name=gpdA1;Function=;Product=Probable glycerol-3-phosphate dehydrogenase GpdA1(pseudogene);Comments=ML2280c, len: 987 bp. Possible pseudogene of M. tuberculosis orthologue gpdA1|Rv0564c (1026 bp) (Best blastx scores: 338).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2739126	2739704	.	+	0	Locus=ML2310A;Name=ML2310A;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2310A, len: 579 bp. Possible pseudogene similar to Q9RJD3 Hypothetical protein SCO0759 from Streptomyces coelicolor (343 aa) (Best blastx score: 151).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2774276	2774823	.	+	0	Locus=ML2339;Name=cut5b;Function=;Product=Probable cutinase precursor Cut5b (pseudogene);Comments=ML2339, len: 548 bp. Possible pseudogene of M. tuberculosis orthologue Rv3724B|cut5b (564 bp) (Best blastx scores: 340).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2838511	2838831	.	-	0	Locus=ML2369B;Name=ML2369B;Function=;Product=Hypothetical protein;Comments=ML2369B, len: 107 aa. Hypothetical protein.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2852008	2854017	.	-	0	Locus=ML2382c;Name=ML2382c;Function=;Product=Probable peptidase (pseudogene);Comments=ML2382c, len: 2010 bp. Possible pseudogene of M. tuberculosis orthologue Rv0457c (2022 bp) (Best blastx scores: 580).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2854121	2855440	.	+	0	Locus=ML2383;Name=ML2383;Function=;Product=Probable aldehyde dehydrogenase (pseudogene);Comments=ML2383, len: 1320 bp. Possible pseudogene of M. tuberculosis orthologue Rv0458 (1524 bp) (Best blastx scores: 356).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2263947	2264707	.	-	0	Locus=ML1885c;Name=echA5;Function=;Product=Probable enoyl-CoA hydratase EchA5 (pseudogene);Comments=ML1885c, len: 761 bp. Possible pseudogene of M. tuberculosis orthologue echA5|Rv0675 (792 bp) (Best blastx scores: 338).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2667230	2667571	.	-	0	Locus=ML2244c;Name=ML2244c;Function=;Product=hypothetical protein;Comments=ML2244c, len: 113 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBC0;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2747159	2747806	.	-	0	Locus=ML2320c;Name=ML2320c;Function=;Product=conserved hypothetical protein;Comments=ML2320c, len: 215 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 22.4 kDa protein Rv3705c TR:O69673 (EMBL:AL022121) (214 aa) fasta scores: E(): 0, 79.4% identity in 214 aa.;UniProt_AC=Q9CB80;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2883438	2884106	.	-	0	Locus=ML2412c;Name=ML2412c;Function=;Product=POSSIBLE THIOREDOXIN PROTEIN (THIOL-DISULFIDE INTERCHANGE PROTEIN);Comments=ML2412c, len: 222 aa. Possible thioredoxin protein (thiol-disulfide interchange protein). Similar to Mycobacterium tuberculosis thioredoxin protein Rv0526 TR:O06392 (EMBL:Z95558) (216 aa) fasta scores: E(): 0, 78.5% identity in 214 aa.;UniProt_AC=Q9CB61;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2292375	2292815	.	-	0	Locus=ML1907c;Name=secE;Function=;Product=PROBABLE PREPROTEIN TRANSLOCASE SECE;Comments=ML1907c, len: 146 aa. Probable secE, preprotein translocase. Similar to M. tuberculosis preprotein translocase SecE subunit Rv0638 SW:SECE_MYCTU (P96929) (161 aa), Fasta scores: E(): 2.2e-19, 61.3% identity in 160 aa overlap, and to many others e.g. Streptomyces virginiae SW:SECE_STRvG (P36691) (93 aa), Fasta scores: E(): 7.9e-08, 41.0% identity in 78 aa overlap. Contains Pfam match to entry PF00584 SecE, SecE/Sec61-gamma subunits of protein translocation complex. Contains PS01067 Protein secE/sec61-gamma signature.;UniProt_AC=Q9CBJ9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2876297	2876749	.	-	0	Locus=ML2404c;Name=galE3;Function=;Product=Possible UDP-glucose 4-epimerase GalE3 (pseudogene);Comments=ML2404c, len: 453 bp. Possible pseudogene of M. tuberculosis orthologue galE3|Rv0536 (1041 bp) (Best blastx scores: 316).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1979765	1980683	.	-	0	Locus=ML1645c;Name=cobD;Function=;Product=Probable cobalamin biosynthesis transmembrane protein CobD (pseudogene);Comments=ML1645c, len: 919 bp. Possible pseudogene of M. tuberculosis orthologue cobD|Rv2236c (942 bp) (Best blastx scores: 204).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2046586	2046950	.	+	0	Locus=ML1697;Name=cfp6;Function=;Product=Low molecular weight protein antigen 6 Cfp6 (pseudogene);Comments=ML1697, len: 365 bp. Possible pseudogene of M. tuberculosis orthologue Rv3004|cfp6 (339 bp) (Best blastx scores: 93).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2063024	2063721	.	-	0	Locus=ML1710c;Name=ML1710c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1710c, len: 698 bp. Possible pseudogene of M. tuberculosis orthologue Rv3027c (741 bp) (Best blastx scores: 295).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2141845	2143220	.	-	0	Locus=ML1767c;Name=ML1767c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1767c, len: 1376 bp. Possible pseudogene of M. tuberculosis orthologue Rv2315c (1518 bp) (Best blastx scores: 309).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2297466	2297949	.	+	0	Locus=ML1914;Name=lpqN;Function=;Product=Probable conserved lipoprotein LpqN (pseudogene);Comments=ML1914, len: 484 bp. Possible pseudogene of M. tuberculosis orthologue lpqN|Rv0583c (687 bp) (Best blastx scores: 198).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2001614	2002267	.	-	0	Locus=ML1660c;Name=ML1660c;Function=;Product=conserved hypothetical protein;Comments=ML1660c, len: 217 aa. Conserved hypothetical protein. Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis Rv2926c TR:YT26_MYCTU (207 aa), fasta scores: E(): 6.5e-53, (67.188% identity in 192 aa overlap).;UniProt_AC=O69468;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2552018	2552428	.	-	0	Locus=ML2147c;Name=cspB;Function=;Product=PROBABLE COLD SHOCK-LIKE PROTEIN B CSPB;Comments=ML2147c, len: 136 aa. Probable cspB, cold shock-like protein. Similar to Mycobacterium tuberculosis cold shock protein b Rv0871 TR:O53883 (EMBL:AL022004) fasta scores: E(): 0, 86.0% in 136 aa, and to Bacillus cereus cold shock-like protein cspc SW:CSPC_BACCE (Q45098) fasta scores: E(): 5.2e-08, 54.4% in 57 aa. Also similar to ML0198 from M. leprae. Contains Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain.;UniProt_AC=O33052;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2329153	2329897	.	-	0	Locus=ML1943c;Name=ML1943c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1943c, len: 745 bp. Possible pseudogene similar to M. tuberculosis Rv3714c (891 bp) (Best blastx scores: 199). Identical to ML1047c and similar to ML2328c possible pseudogenes similar to M. tuberculosis Rv3714c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2366098	2366467	.	+	0	Locus=ML1981;Name=ML1981;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1981, len: 370 bp. Possible pseudogene of M. tuberculosis orthologue Rv1924c (381 bp) (Best blastx scores: 169).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2399865	2400347	.	+	0	Locus=ML2007;Name=ML2007;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2007, len: 483 bp. Possible pseudogene of M. tuberculosis orthologue Rv1907c (648 bp) (Best blastx scores: 281).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2514737	2516708	.	-	0	Locus=ML2115c;Name=ctpE;Function=;Product=Probable metal cation transport ATPase P-type CtpE (pseudogene);Comments=ML2115c, len: 1972 bp. Possible pseudogene of M. tuberculosis orthologue ctpE|Rv0908 (2394 bp) (Best blastx scores: 568).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2516705	2517567	.	-	0	Locus=ML2116c;Name=ML2116c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2116c, len: 863 bp. Possible pseudogene of M. tuberculosis orthologue Rv0907 (1599 bp) (Best blastx scores: 178).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2552602	2552952	.	+	0	Locus=ML2148;Name=ML2148;Function=;Product=Possible conserved integral membrane protein (pseudogene);Comments=ML2148, len: 351 bp. Possible pseudogene of M. tuberculosis orthologue Rv0870c (390 bp) (Best blastx scores: 300).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2553111	2554048	.	+	0	Locus=ML2149;Name=moaA2;Function=;Product=Probable molybdenum cofactor biosynthesis protein A MoaA2 (pseudogene);Comments=ML2149, len: 938 bp. Possible pseudogene of M. tuberculosis orthologue moaA2|Rv0869c (1083 bp) (Best blastx scores: 272).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2554068	2554321	.	+	0	Locus=ML2150;Name=moaD2;Function=;Product=Probable molybdenum cofactor biosynthesis protein MoaD2 (pseudogene);Comments=ML2150, len: 254 bp. Possible pseudogene of M. tuberculosis orthologue moaD2|Rv0868c (279 bp) (Best blastx scores: 134).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2605949	2606705	.	-	0	Locus=ML2191c;Name=ML2191c;Function=;Product=Phosphate-transport integral membrane ABC transporter (pseudogene);Comments=ML2191c, len: 757 bp. Possible pseudogene similar to M. tuberculosis pstC2|Rv0929 (975 bp) (Best blastx scores: 327), also similar to ML2094c a possible orthologue of M. tuberculosis pstC2.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2655609	2656363	.	+	0	Locus=ML2236;Name=ML2236;Function=;Product=REP13E12-family protein (pseudogene);Comments=ML2236, len: 755 bp. Possible pseudogene similar to several M. tuberculosis  conserved hypothetical proteins in REP13E12 degenerate repeate.g. Rv1148, Rv1702, Rv1945, Rv1148, Rv3467 (Best blastx scores: 229).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2759844	2760415	.	-	0	Locus=ML2328c;Name=ML2328c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2328c, len: 572 bp. Possible pseudogene similar to  M. tuberculosis orthologue Rv3714c (891 bp) (Best blastx scores: 159). Also similar to ML1047c and ML1943c possible pseudogenes similar to M. tuberculosis Rv3714c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2786397	2786814	.	+	0	Locus=ML2345;Name=ML2345;Function=;Product=Probable transcriptional regulatory protein (Crp/Fnr family) (pseudogene);Comments=ML2345, len: 418 bp. Possible pseudogene similar to M. tuberculosis Rv3676 (Best blastx scores: 204), also similar to ML2302 a possible orthologue of M. tuberculosis Rv3676.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2312438	2312575	.	-	0	Locus=ML1928c;Name=ML1928c;Function=;Product=hypothetical protein;Comments=ML1928c, len: 45 aa. Hypothetical protein (doutful CDS).;UniProt_AC=Q9CBI3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2336284	2336643	.	-	0	Locus=ML1949c;Name=ML1949c;Function=;Product=hypothetical protein;Comments=ML1949c, len: 119 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBH8;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2707739	2708053	.	+	0	Locus=ML2283;Name=ML2283;Function=;Product=hypothetical protein;Comments=ML2283, len: 104 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBA2;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2731470	2731820	.	-	0	Locus=ML2307c;Name=whiB4;Function=;Product=PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB4;Comments=ML2307c, len: 116 aa. Probable whiB4, WhiB-like regulatory protein. Similar in part to Mycobacterium tuberculosis putative regulatory protein Rv3681c TR:O69649 (EMBL:AL022121) (118 aa) fasta scores: E(): 3e-32, 89.7% identity in 78 aa.;UniProt_AC=Q9CB86;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2479505	2479644	.	+	0	Locus=ML2085;Name=ML2085;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML2085, len: 140 bp. Possible transposase remnant, some similarity to Q9RBZ3 transposase from Pseudomonas syringae (1071 bp), (blastx scores: 51) and to Q44454|Z18270 transposase from Agrobacterium tumefaciens (1098 bp), (blastx scores: 45). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2949487	2950378	.	-	0	Locus=ML2475c;Name=ML2475c;Function=;Product=Possible glycerolphosphodiesterase (pseudogene);Comments=ML2475c, len: 892 bp. Possible pseudogene similar to M. tuberculosis Rv2277c (906 bp) (Best blastx scores: 197).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2471165	2472091	.	-	0	Locus=ML2080c;Name=ML2080c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2080c, len: 927 bp. Possible pseudogene of M. tuberculosis orthologue Rv1823 (924 bp) (Best blastx scores: 305).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2513079	2513807	.	-	0	Locus=ML2112c;Name=ML2112c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2112c, len: 729 bp. Possible pseudogene of M. tuberculosis orthologue Rv0911 (774 bp) (Best blastx scores: 142).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1978482	1978965	.	+	0	Locus=ML1643;Name=ptpA;Function=;Product=Probable low molecular weight protein-tyrosine-phosphatase PtpA (pseudogene);Comments=ML1643, len: 484 bp. Possible pseudogene of M. tuberculosis orthologue ptpA|Rv2234 (492 bp) (Best blastx scores: 453).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1928853	1929242	.	-	0	Locus=ML1604c;Name=ML1604c;Function=;Product=hypothetical protein;Comments=ML1604c, len: 129 aa. Hypothetical unknown protein. Similar in part to Nikkomycin biosynthesis proteins e.g. Q9RCK6 Nikkomycin biosynthesis protein from Streptomyces tendae (471 aa), fasta scores: E(): 0.0019, (49.020% identity in 51 aa overlap).;UniProt_AC=Q9CBT7;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2518777	2519520	.	-	0	Locus=ML2118c;Name=echA6;Function=;Product=POSSIBLE ENOYL-CoA HYDRATASE ECHA6 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE);Comments=ML2118c, len: 247 aa. Possible echA6, enoyl-CoA hydratase (EC 4.2.1.17). Similar to Mycobacterium tuberculosis probable enoyl-coa hydratase echa6|Rv0905 SW:ECH6_MYCTU (Q10533) fasta scores: E(): 0, 85.8% in 247 aa, and to Escherichia coli probable enoyl-coa hydratase paaf SW:PAAF_ECOLI (P76082; P78288; O53014) fasta scores: E(): 3.1e-18, 32.1% in 252 aa. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.;UniProt_AC=Q50130;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2006198	2009582	.	-	0	Locus=ML1665c;Name=pca;Function=;Product=Probable pyruvate carboxylase Pca (pseudogene);Comments=ML1665c, len: 3385 bp. Possible pseudogene of M. tuberculosis orthologue pca|Rv2967c (3384 bp) (Best blastx scores: 873).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2032706	2032837	.	+	0	Locus=ML1687;Name=ML1687;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1687, len: 132 bp. Possible pseudogene of M. tuberculosis orthologue Rv2991 (492 bp) (Best blastx scores: 154).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2097654	2098166	.	-	0	Locus=ML1737c;Name=ML1737c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1737c, len: 513 bp. Possible pseudogene of M. tuberculosis orthologue Rv3054c (555 bp) (Best blastx scores: 267).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2098329	2098918	.	+	0	Locus=ML1738;Name=ML1738;Function=;Product=Possible transcriptional regulatory protein (probably tetR-family (pseudogene);Comments=ML1738, len: 590 bp. Possible pseudogene of M. tuberculosis orthologue Rv3055 (615 bp) (Best blastx scores: 428).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2131618	2132174	.	+	0	Locus=ML1757;Name=ML1757;Function=;Product=Probable transcriptional regulatory protein (deoR-family) (pseudogene);Comments=ML1757, len: 557 bp. Possible pseudogene of M. tuberculosis orthologue Rv3066 (609 bp) (Best blastx scores: 163).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2132593	2132936	.	-	0	Locus=ML1758c;Name=ML1758c;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML1758c, len: 344 bp. Possible pseudogene similar to M. tuberculosis Rv2776c (930 bp) (Best blastx scores: 219). Also similar to ML1529c a possible pseudogene similar to M. tuberculosis Rv2776c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2313265	2313670	.	+	0	Locus=ML1930;Name=ML1930;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1930, len: 406 bp. Possible pseudogene of M. tuberculosis orthologue Rv0428c (909 bp) (Best blastx scores: 239).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2330871	2331244	.	-	0	Locus=ML1944c;Name=ML1944c;Function=;Product=possible IS1081 transposase (pseudogene);Comments=ML1944c, len: 374 bp. Possible pseudogene similar to several IS1081 transposases (Best blastx scores: 63);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2348132	2348287	.	+	0	Locus=ML1963;Name=ML1963;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1963, len: 156 bp. Possible pseudogene of M. tuberculosis orthologue Rv3463 (858 bp) (Best blastx scores: 121).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2365106	2365902	.	-	0	Locus=ML1980c;Name=fadD31;Function=;Product=Probable acyl-CoA synthetase FadD31 (pseudogene);Comments=ML1980c, len: 797 bp. Possible pseudogene of M. tuberculosis orthologue fadD31|Rv1925 (1863 bp) (Best blastx scores: 214).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2540848	2541045	.	-	0	Locus=ML2138c;Name=ML2138c;Function=;Product=Probable transmembrane protein (pseudogene);Comments=ML2138c, len: 198 bp. Possible pseudogene of M. tuberculosis orthologue Rv0882 (285 bp) (Best blastx scores: 124).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2541157	2541956	.	-	0	Locus=ML2139c;Name=ML2139c;Function=;Product=Possible rRNA methyltransferase (pseudogene);Comments=ML2139c, len: 800 bp. Possible pseudogene of M. tuberculosis orthologue Rv0881 (867 bp) (Best blastx scores: 255).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2568750	2569069	.	+	0	Locus=ML2160;Name=ML2160;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML2160, len: 320 bp. Possible pseudogene similar to M. tuberculosis Rv1260 (1119 bp) (Best blastx scores: 80).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2577728	2578742	.	-	0	Locus=ML2168c;Name=fadD16;Function=;Product=Possible fatty-acid-CoA ligase FadD16 (pseudogene);Comments=ML2168c, len: 1015 bp. Possible pseudogene of M. tuberculosis orthologue fadD16|Rv0852 (837 bp) (Best blastx scores: 254).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2581288	2582685	.	+	0	Locus=ML2171;Name=ML2171;Function=;Product=Probable oxidase (pseudogene);Comments=ML2171, len: 1398 bp. Possible pseudogene of M. tuberculosis orthologue Rv0846c (1515 bp) (Best blastx scores: 209).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2602119	2603522	.	+	0	Locus=ML2187;Name=ML2187;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2187, len: 1404 bp. Possible pseudogene of M. tuberculosis orthologue Rv0822c (2055 bp) (Best blastx scores: 723).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2325746	2326363	.	+	0	Locus=ML1939;Name=ML1939;Function=;Product=conserved hypothetical protein;Comments=ML1939, len: 205 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetical protein Rv1109c.;UniProt_AC=Q9X782;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2784600	2785371	.	-	0	Locus=ML2344c;Name=ML2344c;Function=;Product=Probable conserved integral membrane transport protein (pseudogene);Comments=ML2344c, len: 772 bp. Possible pseudogene similar to M. tuberculosis Rv1200 (1278 bp) (Best blastx scores: 189).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2826438	2827088	.	+	0	Locus=ML2361;Name=tcrX;Function=;Product=Probable two-component transcriptional regulatory protein TcrX (pseudogene);Comments=ML2361, len: 651 bp. Possible pseudogene of M. tuberculosis orthologue Rv3765c|tcrX (705 bp) (Best blastx scores: 195).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2234751	2235617	.	-	0	Locus=ML1851c;Name=ML1851c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1851c, len: 867 bp. Possible pseudogene of M. tuberculosis orthologue Rv0712 (900 bp) (Best blastx scores: 304).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2849887	2850216	.	-	0	Locus=ML2379c;Name=ML2379c;Function=;Product=Conserved hypothetical protein;Comments=ML2379c, len: 109 aa. Conserved hypothetical protein, similar in part to Q8VKL1 Hypothetical protein MT0470 from M. tuberculosis CDC1551 (184 aa), fasta scores: E(): 7.2e-26, (58.879% identity  in 107 aa overlap).;UniProt_AC=Q9CB69;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1919061	1920363	.	-	0	Locus=ML1594c;Name=ML1594c;Function=;Product=Possible multidrug resistance integral membrane efflux protein (pseudogene);Comments=ML1594c, len: 1303 bp. Possible pseudogene similar to M. tuberculosis Rv0783c|emrB (1623 bp) (Best blastx scores: 335). Also similar to ML2224 a possible pseudogene similar to M. tuberculosis emrB.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2283641	2284555	.	+	0	Locus=ML1899;Name=lipG;Function=;Product=PROBABLE LIPASE/ESTERASE LIPG;Comments=ML1899, len: 304 aa. probable lipG, lipase/esterase (EC 3.1.-.-). Similar to M. tuberculosis putative hydrolase Rv0646c TR:P96935 (EMBL:Z92772) (301 aa), Fasta scores: E(): 0, 71.3% identity in 303 aa overlap, and to others e.g. Escherichia coli macrolide 2'-phosphotransferase II TR:P77026 (EMBL:D85892) (279 aa), Fasta scores: E(): 1.3e-15, 31.3% identity in 291 aa overlap, and Streptomyces peucetius 10-carbomethoxy-13-deoxycarminomycin esterase TR:Q54809 (EMBL:L40425) (298 aa), Fasta scores: E(): 1e-09, 28.6% identity in 301 aa overlap. Also similar to ML0862 from M. leprae. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.;UniProt_AC=Q9CBK5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2636683	2636922	.	-	0	Locus=ML2219A;Name=ML2219A;Function=;Product=conserved hypothetical protein;Comments=ML2219A, len: 79 aa. Conserved hypothetical protein. Similar to M. tuberculosis Rv0787A Conserved hypothetical protein (79 aa) fasta scores: E(): 4.7e-27, (84.810% identity in 79 aa overlap). Similar to various hypothetical proteins e.g. Streptomyces coelicolor hypothetical protein Q9RKK7 Hypothetical protein SCO4077 (90 aa), fasta scores: E(): 3.6e-18, (68.293% identity in 82 aa overlap).;UniProt_AC=;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2244678	2245156	.	-	0	Locus=ML1865c;Name=ML1865c;Function=;Product=PE-family protein (pseudogene);Comments=ML1865c, len: 479 bp. Possible pseudogene similar to M. tuberculosis PE-family proteins e.g. PE16|Rv1430, PE3|Rv0159c and PE4|Rv0160c (Best blastx scores: 125).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2281688	2281959	.	-	0	Locus=ML1897c;Name=ML1897c;Function=;Product=Possible sugar kinase (pseudogene);Comments=ML1897c, len: 272 bp. Possible pseudogene of M. tuberculosis orthologue Rv0650 (909 bp)(Best blastx scores: 139).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2285632	2286499	.	+	0	Locus=ML1901;Name=mmaA2;Function=;Product=Methoxy mycolic acid synthase 2 MmaA2 (pseudogene);Comments=ML1901, len: 868 bp. Possible pseudogene of M. tuberculosis orthologue mmaA2|Rv0644c (864 bp) (Best blastx scores: 452).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2415028	2416234	.	+	0	Locus=ML2024;Name=cyp125;Function=;Product=Probable cytochrome p450 125 Cyp125 (pseudogene);Comments=ML2024, len: 1207 bp. Possible pseudogene similar to M. tuberculosis Rv3545c|cyp125 (1302 bp) (Best blastx scores: 411);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2469901	2470592	.	-	0	Locus=ML2078c;Name=ML2078c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2078c, len: 692 bp. Possible pseudogene of M. tuberculosis orthologue Rv1825 (879 bp) (Best blastx scores: 286).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2548830	2550699	.	-	0	Locus=ML2146c;Name=fadE10;Function=;Product=Probable acyl-CoA dehydrogenase FadE10 (pseudogene);Comments=ML2146c, len: 1870 bp. Possible pseudogene of M. tuberculosis orthologue fadE10|Rv0873 (1953 bp) (Best blastx scores: 502).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2595838	2596418	.	-	0	Locus=ML2181c;Name=ML2181c;Function=;Product=conserved hypothetical protein (pseudogene);Comments=ML2181c, len: 581 bp. Possible pseudogene of M. tuberculosis orthologue Rv0830 (906 bp) (Best blastx scores: 192).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2616775	2617645	.	-	0	Locus=ML2202c;Name=ML2202c;Function=;Product=Probable amino acid aminotransferase (pseudogene);Comments=ML2202c, len: 871 bp. Possible pseudogene of M. tuberculosis orthologue Rv0812 (870 bp) (Best blastx scores: 299).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2622752	2623866	.	+	0	Locus=ML2208;Name=ML2208;Function=;Product=Mce-family protein (pseudogene);Comments=ML2208, len: 1115 bp. Possible pseudogene similar to several M. tuberculosis Mce proteins e.g. mce2A|Rv0589 and mce1A|Rv0169 (Best blastx scores: 226).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2646621	2647490	.	-	0	Locus=ML2229c;Name=cyp126;Function=;Product=Possible cytochrome P450 126 Cyp126 (pseudogene);Comments=ML2229c, len: 870 bp. Possible pseudogene of M. tuberculosis orthologue Rv0778|cyp126 (1245 bp) (Best blastx scores: 305).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2680331	2681328	.	-	0	Locus=ML2256c;Name=ML2256c;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML2256c, len: 998 bp. Possible pseudogene of M. tuberculosis orthologue Rv0541c (1350 bp) (Best blastx scores: 212).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2253886	2254576	.	-	0	Locus=ML1875c;Name=ML1875c;Function=;Product=Probable short-chain dehydrogenase/reductase (pseudogene);Comments=ML1875c, len: 691 bp. Possible pseudogene of M. tuberculosis orthologue Rv0687 (828 bp) (Best blastx scores: 122).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2254850	2255518	.	-	0	Locus=ML1876c;Name=ML1876c;Function=;Product=Probable membrane protein (pseudogene);Comments=ML1876c, len: 669 bp. Possible pseudogene of M. tuberculosis orthologue Rv0686 (798 bp) (Best blastx scores: 157).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2672727	2673044	.	-	0	Locus=ML2249c;Name=ML2249c;Function=;Product=hypothetical protein;Comments=ML2249c, len: 105 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBB9;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2735800	2736727	.	+	0	Locus=ML2310;Name=ML2310;Function=;Product=Probable lyase, cysteine metabolism (pseudogene);Comments=ML2310, len: 928 bp. Possible pseudogene of M. tuberculosis orthologue Rv3684 (1041 bp) (Best blastx scores: 298).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2781969	2782724	.	-	0	Locus=ML2342c;Name=ML2342c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2342c, len: 756 bp. Possible pseudogene of M. tuberculosis orthologue Rv3730c (1041 bp) (Best blastx scores: 278);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2851047	2851927	.	-	0	Locus=ML2381c;Name=echA2;Function=;Product=Enoyl-CoA hydratase EchA2 (pseudogene);Comments=ML2381c, len: 881 bp. Possible pseudogene of M. tuberculosis orthologue echA2|Rv0456c (915 bp) (Best blastx scores: 203).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2740952	2741554	.	+	0	Locus=ML2313;Name=ML2313;Function=;Product=conserved hypothetical protein;Comments=ML2313, len: 200 aa. Conserved hypothetical protein. Similar to several hypothetical proteins e.g. Q827D0 Hypothetical protein from Streptomyces avermitilis (217 aa), fasta scores: E(): 4.8e-28, (49.468% identity in 188 aa overlap);UniProt_AC=Q9CB82;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2862586	2863020	.	+	0	Locus=ML2392;Name=ML2392;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN;Comments=ML2392, len: 144 aa. Probable conserved membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv1081c TR:O53429 (EMBL:AL021897) (144 aa) fasta scores: E(): 0, 69.0% id in 142 aa. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9CB66;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2016967	2018398	.	-	0	Locus=ML1672c;Name=ML1672c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1672c, len: 1432 bp. Possible pseudogene of M. tuberculosis orthologue Rv2974c (1413 bp) (Best blastx scores: 719).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1913064	1913881	.	-	0	Locus=ML1588c;Name=ML1588c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1588c, len: 818 bp. Possible pseudogene of M. tuberculosis orthologue Rv2880c (828 BP) (Best blastx scores: 295).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1917195	1917871	.	+	0	Locus=ML1592;Name=ML1592;Function=;Product=Probable transcriptional regulatory protein (pseudogene);Comments=ML1592, len: 677 bp. Possible pseudogene of M. tuberculosis orthologue Rv2884 (759 bp) (Best blastx scores: 260).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1928383	1928643	.	-	0	Locus=ML1603c;Name=ML1603c;Function=;Product=hypothetical protein;Comments=ML1603c, len: 86 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBT8;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2295531	2296247	.	+	0	Locus=ML1912;Name=ML1912;Function=;Product=POSSIBLE GLYOXALASE II (HYDROXYACYLGLUTATHIONE HYDROLASE) (GLX II);Comments=ML1912, len: 238 aa. Possible glyoxylase II (EC 3.1.2.6). Similar to M. tuberculosis putative glyoxylase II Rv0634c, to hypothetical proteins belonging to the glyoxalase II family e.g. Escherichia coli SW:YCBL_ECOLI (P75849) (215 aa), Fasta scores: E(): 3.5e-12, 32.5% identity in 203 aa overlap. Also similar to ML0493, ML2303 and ML1391 from M. leprae. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily.;UniProt_AC=Q9CBJ4;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1937826	1938729	.	+	0	Locus=ML1614;Name=lppW;Function=;Product=Probable conserved alanine rich lipoprotein LppW (pseudogene);Comments=ML1614, len: 904 bp. Possible pseudogene of M. tuberculosis orthologue lppW|Rv2905 (945 bp) (Best blastx scores: 203).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1935027	1935332	.	-	0	Locus=ML1610c;Name=ML1610c;Function=;Product=conserved hypothetical protein;Comments=ML1610c, len: 101 aa. Conserved hypothetical protein. Similar to several proteins of unknown function from Mycobacterium tuberculosis e.g. Rv2901c SW:YT01_MYCTU (Q10822) (101 aa), Fasta scores: E(): 0, 99.0% identity in 101 aa overlap.;UniProt_AC=O33023;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2205037	2205312	.	-	0	Locus=ML1821A;Name=ML1821A;Function=;Product=conserved hypothetical protein;Comments=ML1821A, len: 92 aa. Conserved hypothetical protein. Similar to the N-terminal region of Q8GE87 Hypothetical protein from M. avium (186 aa), fasta scores: E(): 9.4e-13, (47.312% identity in 93 aa overlap). Homology to Q8GE87 continues upstream of this ORF in a different frame suggesting a possible frameshift. ;UniProt_AC=;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1932707	1932997	.	-	0	Locus=ML1607c;Name=ML1607c;Function=;Product=conserved hypothetical protein;Comments=ML1607c, len: 96 aa.  Conserved hypothetical protein. Similar to N terminus of Mycobacterium tuberculosis hypothetical protein Rv2898c SW:YS98_MYCTU (Q10819) (128 aa), Fasta scores: E(): 7.9e-19, 58.3% identity in 96 aa overlap. Contains Pfam match to entry PF02021 UPF0102, Uncharacterised protein family UPF0102.;UniProt_AC=O33024;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2361841	2362418	.	+	0	Locus=ML1977;Name=ML1977;Function=;Product=Possible conserved membrane protein (pseudogene);Comments=ML1977, len: 578 bp. Possible pseudogene similar to M. tuberculosis Rv2025c (999 bp) (Best blastx scores: 209).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1938746	1939462	.	-	0	Locus=ML1615c;Name=trmD;Function=;Product=PROBABLE TRNA (GUANINE-N1)-METHYLTRANSFERASE TRMD (M1G-METHYLTRANSFERASE) (TRNA [GM37] METHYLTRANSFERASE);Comments=ML1615c, len: 238 aa. Probable trmD, tRNA (guanine-N1)-methyltransferase (EC 2.1.1.31). Highly similar to many tRNA (guanine-N1) methyltransferases including: Escherichia coli SW:TRMD_ECOLI (P07020) (255 aa), Fasta scores: E(): 5.4e-33, 43.5% identity in 230 aa overlap and Mycobacterium tuberculosis Rv2906c SW:TRMD_MYCTU (Q10797) (230 aa), Fasta scores: E(): 0, 87.7% identity in 227 aa overlap. Contains Pfam match to entry PF01746 tRNA_m1G_MT, tRNA (Guanine-1)-methyltransferase.;UniProt_AC=O33017;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1947644	1949434	.	+	0	Locus=ML1624;Name=ML1624;Function=;Product=conserved hypothetical protein;Comments=ML1624, len: 596 aa. Conserved hypothetical protein. Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis Rv2917 SW:YT17_MYCTU (Q10966) (626 aa), Fasta scores: E(): 0, 79.8% identity in 584 aa overlap and Streptomyces coelicolor TR:Q9S3Y6 (EMBL:AF170560) (597 aa), Fasta scores: E(): 0, 55.5% identity in 566 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O33011;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1977066	1978059	.	-	0	Locus=ML1640c;Name=cobC;Function=;Product=Possible aminotransferase CobC (pseudogene);Comments=ML1640c, len: 994 bp. Possible pseudogene of M. tuberculosis orthologue cobC|Rv2231c (1095 bp) (Best blastx scores: 299).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1978112	1978453	.	+	0	Locus=ML1641;Name=ML1641;Function=;Product=conserved hypothetical protein (pseudogene);Comments=ML1641, len: 342 bp. Possible pseudogene of M. tuberculosis orthologue Rv2232 (876 bp) (Best blastx scores: 218).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1987836	1988258	.	-	0	Locus=ML1649c;Name=ML1649c;Function=;Product=conserved hypothetical protein;Comments=ML1649c, len: 140 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2239c SW:YM39_MYCTU (Q10521) (158 aa), Fasta scores: E(): 0, 86.4% identity in 140 aa overlap.;UniProt_AC=O69479;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1978968	1979780	.	+	0	Locus=ML1644;Name=ML1644;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML1644, len: 270 aa. Probable conserved transmembrane protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2235 SW:YM35_MYCTU (Q10517) (271 aa), Fasta scores: E(): 0, 74.2% identity in 271 aa overlap. Contains a possible N-terminal signal sequence and another possible membrane spanning hydrophobic domain.;UniProt_AC=O69480;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2011299	2012081	.	-	0	Locus=ML1668c;Name=lipN;Function=;Product=Probable lipase/esterase LipN (pseudogene);Comments=ML1668c, len: 783 bp. Possible pseudogene of M. tuberculosis orthologue lipN|Rv2970c (1131 bp) (Best blastx scores: 135).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2012255	2012911	.	+	0	Locus=ML1668A;Name=ML1668A;Function=;Product=Putative oxidoreductase (pseudogene);Comments=ML1668A, len: 657 bp. Possible pseudogene similar to several Putative oxidoreductases e.g. Q82M11 from Streptomyces avermitilis (278 aa) (Best blastx score: 173).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2002301	2003044	.	-	0	Locus=ML1661c;Name=ML1661c;Function=;Product=conserved hypothetical protein;Comments=ML1661c, len: 247 aa. Conserved hypothetical protein. Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis Rv2927c TR:YT27_MYCTU (245 aa), fasta scores: E(): 6.7e-80, (90.204% identity in 245 aa overlap).;UniProt_AC=Q9CBS6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2010261	2011055	.	-	0	Locus=ML1667c;Name=ML1667c;Function=;Product=POSSIBLE CONSERVED MEMBRANE OR SECRETED PROTEIN;Comments=ML1667c, len: 264 aa. Possible conserved membrane or secreted protein. Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis Rv2969c TR:O33272 (EMBL:Z83018) (255 aa), Fasta scores: E(): 0, 65.5% identity in 258 aa overlap. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9CBS4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2013982	2014639	.	-	0	Locus=ML1670c;Name=ML1670c;Function=;Product=Possible conserved membrane or exported protein (pseudogene);Comments=ML1670c, len: 658 bp. Possible pseudogene of M. tuberculosis orthologue Rv2972c (714 bp) (Best blastx scores: 445).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2018449	2018649	.	-	0	Locus=ML1673c;Name=ML1673c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1673c, len: 201 bp. Possible pseudogene of M. tuberculosis orthologue Rv2975c (255 bp) (Best blastx scores: 88.);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2018913	2019179	.	+	0	Locus=ML1674;Name=ML1674;Function=;Product=50S ribosomal protein L28 (pseudogene);Comments=ML1674, len: 267 bp. Possible pseudogene similar to the M. tuberculosis 50S ribosomal proteins rpmB2|Rv2058 and rpmB1|Rv0105c (Best blastx scores: 125).;UniProt_AC=P68998;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2156725	2157666	.	+	0	Locus=ML1780;Name=ML1780;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1780, len: 942 bp. Possible pseudogene of M. tuberculosis orthologue Rv2252 (930 bp) (Best blastx scores: 590).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2021242	2021817	.	+	0	Locus=ML1677;Name=ML1677;Function=;Product=POSSIBLE CONSERVED SECRETED PROTEIN;Comments=ML1677, len: 191 aa. Possible conserved secreted protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2980 TR:P95115 (EMBL:Z83018) (181 aa), Fasta scores: E(): 0, 67.2% identity in 177 aa overlap. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CBS1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2265611	2266563	.	-	0	Locus=ML1887c;Name=echA4;Function=;Product=Possible enoyl-CoA hydratase EchA4 (pseudogene);Comments=ML1887c, len: 953. Possible pseudogene of M. tuberculosis orthologue echA4|Rv0673 (939 bp) (Best blastx scores: 408).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2362448	2363083	.	+	0	Locus=ML1978;Name=ML1978;Function=;Product=Probable epoxide hydrolase (pseudogene);Comments=ML1978, len: 636 bp. Possible pseudogene similar to several M. tuberculosis probable epoxide hydrolases e.g. ephB|Rv1938, ephF|Rv0134, ephA|Rv3617, ephC|Rv1124 and ephE|Rv3670 (Best blastx scores: 132).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2214820	2215197	.	+	0	Locus=ML1829;Name=ML1829;Function=;Product=hypothetical protein;Comments=ML1829, len: 125 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBK9;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2157680	2158192	.	-	0	Locus=ML1781c;Name=ML1781c;Function=;Product=conserved hypothetical protein;Comments=ML1781c, len: 170. Conserved hypothetical protein. Similar to M. tuberculosis Rv2256c TR:O53530 (EMBL:AL021925) (177 aa), Fasta scores: E(): 0, 93.5% identity in 170 aa overlap, and to other hypothetical proteins e.g. TR:Q54209 (EMBL:L43074) unknown ORF downstream of Streptomyces glaucescens fabB (164 aa), Fasta scores: E(): 3.8e-27, 46.9% identity in 162 aa overlap.;UniProt_AC=Q9CBN5;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2073484	2073991	.	+	0	Locus=ML1718;Name=ML1718;Function=;Product=Probable 3-methyl-2-oxobutanoate hydroxymethyltransferase (pseudogene);Comments=ML1718, len: 508 bp. Possible pseudogene similar to M. tuberculosis panB|Rv2225 (846 bp) (Best blastx scores: 104), also similar to ML1635 a possible orthologue of M. tuberculosis panB.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2077989	2079654	.	-	0	Locus=ML1722c;Name=ML1722c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1722c, len: 1666 bp. Possible pseudogene of M. tuberculosis orthologue Rv3037c (1077 bp) (Best blastx scores: 298). Similarity to Rv3037 appears to have been intersected by the repeat element.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2077206	2077904	.	-	0	Locus=ML1721c;Name=ML1721c;Function=;Product=Probable conserved secreted protein TB22.2 homolog (pseudogene);Comments=ML1721c, len: 699 bp. Possible pseudogene of M. tuberculosis orthologue Rv3036c|TB22.2 (684 bp) (Best blastx scores: 382).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2266578	2268074	.	-	0	Locus=ML1888c;Name=fadE8;Function=;Product=Probable acyl-CoA dehydrogenase FadE8 (pseudogene);Comments=ML1888c, len: 1497 bp. Possible pseudogene of M. tuberculosis orthologue fadE8|Rv0672 (1629 bp) (Best blastx scores: 347).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2066115	2066957	.	+	0	Locus=ML1713;Name=ML1713;Function=;Product=conserved hypothetical protein;Comments=ML1713, len: 280 aa. Conserved hypothetical protein. Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis Rv3030 TR:O53277 (EMBL:AL021287) (274 aa), Fasta scores: E(): 0, 78.2% identity in 280 aa overlap.;UniProt_AC=O33094;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2356318	2356548	.	-	0	Locus=ML1972c;Name=ML1972c;Function=;Product=hypothetical protein;Comments=ML1972c, len: 76 aa.  Hypothetical unknown protein.;UniProt_AC=Q9CBH6;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2091760	2093242	.	-	0	Locus=ML1732c;Name=ML1732c;Function=;Product=Probable monooxygenase (pseudogene);Comments=ML1732c, len: 1483 bp. Possible pseudogene of M. tuberculosis orthologue Rv3049c (1575 bp) (Best blastx scores: 1312).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2076108	2077202	.	+	0	Locus=ML1720;Name=ML1720;Function=;Product=conserved hypothetical protein;Comments=ML1720, len: 364 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv3035 TR:O53282 (EMBL:AL021287) (360 aa), Fasta scores: E(): 0, 75.8% identity in 363 aa overlap.;UniProt_AC=Q9CBR0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2079782	2080765	.	-	0	Locus=ML1723c;Name=ML1723c;Function=;Product=conserved hypothetical protein;Comments=ML1723c, len: 327 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv3038c TR:O53285 (EMBL:AL021287) (327 aa), Fasta scores: E(): 0, 80.7% identity in 327 aa overlap.;UniProt_AC=Q9CBQ9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2355416	2355555	.	-	0	Locus=ML1971c;Name=ML1971c;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML1971c, len: 140 bp. Possible transposase remnant, some similarity to Q9RBZ3 transposase from Pseudomonas syringae (1071 bp), (blastx scores: 51) and to Q44454|Z18270 transposase from Agrobacterium tumefaciens (1098 bp), (blastx scores: 41). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2093457	2094284	.	-	0	Locus=ML1733c;Name=ML1733c;Function=;Product=Probable transcriptional regulatory protein tetR-family;Comments=ML1733c, len: 275 aa. Probable transcriptional regulatory protein tetR-family. Similar to Mycobacterium tuberculosis Rv3050c TR:O53295 (EMBL:AL021287) (246 aa), Fasta scores: E(): 0, 86.6% identity in 238 aa overlap. Contains a putative helix-turn-helix motif situated between residues 79..100 (+3.98 SD). Contains a probable helix-turn-helix motif at aa 79-100 (Score 1407, SD +3.98) Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family.;UniProt_AC=Q9CBQ1;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2106686	2108853	.	-	0	Locus=ML1745c;Name=fadE22;Function=;Product=Probable acyl-CoA dehydrogenase FadE22 (pseudogene);Comments=ML1745c, len: 2168 bp. Possible pseudogene of M. tuberculosis orthologue fadE22|Rv3061c (2166 bp) (Best blastx scores: 1078).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2109182	2109549	.	-	0	Locus=ML1746c;Name=ML1746c;Function=;Product=Probable short-chain dehydrogenase/reductase (pseudogene);Comments=ML1746c, len: 368 bp. Possible pseudogene similar to M. tuberculosis Rv1144 (753 bp) (Best blastx scores: 107). Also similar to ML0970 a possible pseudogene similar to M. tuberculosis Rv1144.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2110117	2111057	.	+	0	Locus=ML1748;Name=cstA;Function=;Product=Probable carbon starvation protein A homolog CstA (pseudogene);Comments=ML1748, len: 941 bp. Possible pseudogene of M. tuberculosis orthologue cstA|Rv3063 (2277 bp) (Best blastx scores: 200).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2357584	2358387	.	+	0	Locus=ML1973;Name=ML1973;Function=;Product=Possible beta-1,3-glucanase precursor (pseudogene);Comments=ML1973, len: 804 bp. Possible pseudogene similar to M. tuberculosis Rv0315 (885 bp) (Best blastx scores: 130). Also similar to ML2516c a possible pseudogene similar to M. tuberculosis Rv0315.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2096942	2097184	.	-	0	Locus=ML1736c;Name=nrdH;Function=;Product=PROBABLE GLUTAREDOXIN ELECTRON TRANSPORT COMPONENT OF NRDEF (GLUTAREDOXIN-LIKE PROTEIN) NRDH;Comments=ML1736c, len: 80 aa. Probable nrdH, glutaredoxin electron transport component of NrdE. Highly similar to many glutaredoxin-like proteins involved in electron transport for the ribonucleotide reductase system NrdEF, including: Escherichia coli SW:NRDH_ECOLI (Q47414) (81 aa), Fasta scores: E(): 1.1e-11, 44.0% identity in 75 aa overlap and Mycobacterium tuberculosis Rv3053c TR:P95106 (EMBL:Z83866) (79 aa), Fasta scores: E(): 7.7e-31, 91.1% identity in 79 aa overlap.;UniProt_AC=Q9CBP8;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2096497	2096913	.	-	0	Locus=ML1735c;Name=nrdI;Function=;Product=Probable NrdI-family protein;Comments=ML1735c, len: 138 aa. Probable NrdI-family protein. Highly similar to many NrdI-family proteins, the function of which are unknown but thought to be involved with ribonucleoside reductase functioning, including: Escherichia coli SW:NRDI_ECOLI (Q47415) (136 aa), Fasta scores: E(): 2.7e-31, 59.3% identity in 135 aa overlap and Mycobacterium tuberculosis Rv3052c SW:NRDI_MYCTU (P95107) (150 aa), Fasta scores: E(): 0, 79.7% identity in 138 aa overlap.;UniProt_AC=Q9CBP9;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2133997	2134969	.	-	0	Locus=ML1759c;Name=pgmA;Function=;Product=Probable phosphoglucomutase PgmA (pseudogene);Comments=ML1759c, len: 973 bp. Possible pseudogene of M. tuberculosis orthologue pgmA|Rv3068c (1644 bp) (Best blastx scores: 432).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2135609	2135852	.	-	0	Locus=ML1760c;Name=ML1760c;Function=;Product=Possible integrase (fragment) (pseudogene);Comments=ML1760c, len: 244 bp. Possible pseudogene of M. tuberculosis orthologue Rv2309c (Best blastx scores: 88);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2136886	2137949	.	-	0	Locus=ML1762c;Name=ML1762c;Function=;Product=Probable conserved integral membrane alanine, valine and leucine rich protein (pseudogene);Comments=ML1762c, len: 1064 bp. Possible pseudogene similar to M. tuberculosis Rv2690c (1974 bp) (Best blastx scores: 105).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2139554	2139880	.	+	0	Locus=ML1764;Name=ML1764;Function=;Product=putative potassium transport protein (pseudogene);Comments=ML1764, len: 327 bp. Possible pseudogene fragment, similar to part of several trkA (potassium transport) genes e.g. TRKA_METTH|O27333 (216 aa), Fasta scores: E(): 1.3, (33.8% identity in 71 aa overlap).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2140232	2140634	.	-	0	Locus=ML1765c;Name=ML1765c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1765c, len: 403 bp. Possible pseudogene of M. tuberculosis orthologue Rv2313c (855 bp) (Best blastx scores: 125).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2146521	2147343	.	-	0	Locus=ML1771c;Name=ML1771c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1771c, len: 823 bp. Possible pseudogene of M. tuberculosis orthologue Rv2319c (879 bp) (Best blastx scores: 252).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2147420	2148621	.	-	0	Locus=ML1772c;Name=rocE;Function=;Product=Probable cationic amino acid transport integral membrane protein RocE (pseudogene);Comments=ML1772c, len: 1202 bp. Possible pseudogene of M. tuberculosis orthologue rocE|Rv2320c (1431 bp) (Best blastx scores: 518).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2148760	2149231	.	-	0	Locus=ML1773c;Name=rocD2;Function=;Product=Probable ornithine aminotransferase RocD2 (pseudogene);Comments=ML1773c, len: 472 bp. Possible pseudogene of M. tuberculosis orthologue rocD2|Rv2321c (546 bp) (Best blastx scores: 246).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2149256	2149876	.	-	0	Locus=ML1774c;Name=rocD1;Function=;Product=Probable ornithine aminotransferase RocD1 (pseudogene);Comments=ML1774c, len: 621 bp. Possible pseudogene of M. tuberculosis orthologue rocD1|Rv2322c (666 bp) (Best blastx scores: 214).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2149927	2150544	.	-	0	Locus=ML1775c;Name=ML1775c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1775c, len: 618 bp. Possible pseudogene of M. tuberculosis orthologue Rv2323c (909 bp) (Best blastx scores: 122).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2150636	2151084	.	+	0	Locus=ML1776;Name=ML1776;Function=;Product=Probable transcriptional regulatory protein (Lrp/AsnC family) (pseudogene);Comments=ML1776, len: 449 bp. Possible pseudogene of M. tuberculosis orthologue Rv2324 (447 bp) (Best blastx scores: 201).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2153068	2154499	.	-	0	Locus=ML1777c;Name=glpD1;Function=;Product=Probable glycerol-3-phosphate dehydrogenase GlpD1 (pseudogene);Comments=ML1777c, len: 1432 bp. Possible pseudogene of M. tuberculosis orthologue glpD1|Rv2249c (1551 bp) (Best blastx scores: 420).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2154522	2155160	.	-	0	Locus=ML1778c;Name=ML1778c;Function=;Product=Possible transcriptional regulatory protein (pseudogene);Comments=ML1778c, len: 639 bp. Possible pseudogene of M. tuberculosis orthologue Rv2250c (570 bp) (Best blastx scores: 307).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2155439	2156725	.	+	0	Locus=ML1779;Name=ML1779;Function=;Product=Possible flavoprotein (pseudogene);Comments=ML1779, len: 1287 bp. Possible pseudogene of M. tuberculosis orthologue Rv2251 (1428 bp) (Best blastx scores: 327);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2136034	2136378	.	-	0	Locus=ML1761c;Name=ML1761c;Function=;Product=hypothetical protein;Comments=ML1761c, len: 114 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBP0;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2293655	2294083	.	-	0	Locus=ML1909c;Name=ML1909c;Function=;Product=conserved hypothetical protein;Comments=ML1909c, len: 142 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetical protein Rv0636 TR:P96927 (EMBL:Z92772) (142 aa), Fasta scores: E(): 0, 93.0% identity in 142 aa overlap. Also similar to ML2566 from M. leprae. Contains Pfam match to entry PF01575 MaoC_dehydratas, MaoC like domain.;UniProt_AC=Q9CBJ7;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2161364	2161605	.	+	0	Locus=ML1785;Name=ML1785;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1785, len: 242 bp. Possible pseudogene of M. tuberculosis orthologue Rv2260 (636 bp) (Best blastx scores: 156).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2162536	2162837	.	-	0	Locus=ML1786c;Name=ML1786c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1786c, len: 302 bp. Possible pseudogene of M. tuberculosis orthologue Rv2261c (423 bp) (Best blastx scores: 202).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2163102	2163387	.	+	0	Locus=ML1787;Name=cyp124;Function=;Product=Probable cytochrome P-450 124 Cyp124 (pseudogene);Comments=ML1787, len: 286 bp. Possible pseudogene of M. tuberculosis orthologue Rv2266|cyp124 (1287 bp) (Best blastx scores: 246).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2164151	2164501	.	+	0	Locus=ML1789;Name=ML1789;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML1789, len: 351 bp. Possible pseudogene of M. tuberculosis orthologue Rv2272 (369 bp) (Best blastx scores: 221).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2164522	2164820	.	+	0	Locus=ML1790;Name=ML1790;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML1790, len: 299 bp. Possible pseudogene of M. tuberculosis orthologue Rv2273 (330 bp) (Best blastx scores: 80).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2166754	2168343	.	+	0	Locus=ML1792;Name=yjcE;Function=;Product=Probable conserved integral membrane transport protein YjcE (pseudogene);Comments=ML1792, len: 1590 bp. Possible pseudogene of M. tuberculosis orthologue yjcE|Rv2287  (1629 bp) (Best blastx scores: 885).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2176417	2176785	.	-	0	Locus=ML1797c;Name=lipL;Function=;Product=Probable esterase LipL (pseudogene);Comments=ML1797c, len: 369 bp. Possible pseudogene similar to M. tuberculosis orthologue lipL|Rv1497 (1290 bp) (Best blastx scores: 94).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2182292	2182977	.	+	0	Locus=ML1801;Name=ML1801;Function=;Product=Conserved membrane protein (pseudogene);Comments=ML1801, len: 686 bp. Possible pseudogene of M. tuberculosis orthologue Rv1491c (759 bp) (Best blastx scores: 268).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2211568	2211769	.	-	0	Locus=ML1826c;Name=cobU;Function=;Product=Probable bifunctional cobalamin biosynthesis protein CobU: cobinamide kinase + cobinamide phosphate guanyltransferase (pseudogene);Comments=ML1826c, len: 202 bp. Possible pseudogene of M. tuberculosis orthologue cobU|Rv0254c (525 bp0 (Best blastx scores: 185).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2175309	2175722	.	+	0	Locus=ML1796;Name=ML1796;Function=;Product=hypothetical protein;Comments=ML1796, len: 137 aa. Hypothetical unknown protein, previously sequenced as Y15K_MYCLE|P13733 (137 aa), Fasta scores: E(): 0, 100.0% identity in 137 aa overlap.;UniProt_AC=P13733;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2210336	2210475	.	-	0	Locus=ML1825c;Name=ML1825c;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML1825c, len: 140 bp. Possible transposase remnant, some similarity to Q9RBZ3 transposase from Pseudomonas syringae (1071 bp), (blastx scores: 51) and to Q44454|Z18270 transposase from Agrobacterium tumefaciens (1098 bp), (blastx scores: 45). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2214304	2214507	.	+	0	Locus=ML1828A;Name=ML1828A;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1828A, len: 204 bp.  Possible pseudogene of M. tuberculosis orthologue Rv0257 (375 bp) (Best blastx scores: 186).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2433663	2434137	.	+	0	Locus=ML2043;Name=ahpD;Function=;Product=Alkyl hydroperoxide reductase AhpD (pseudogene);Comments=ML2043, len: 475 bp. Possible pseudogene of M. tuberculosis orthologue ahpD|Rv2429 (534 bp) (Best blastx scores: 150).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2184363	2184794	.	-	0	Locus=ML1803c;Name=ML1803c;Function=;Product=CONSERVED MEMBRANE PROTEIN;Comments=ML1803c, len: 143 aa. Conserved membrane protein. Similar to M. tuberculosis Rv1487 TR:P71767 (EMBL:Z79701) (144 aa), Fasta scores: E(): 0, 74.8% identity in 143 aa overlap, and to many others e.g. Streptomyces coelicolor putative integral membrane protein SCI5.05C TR:Q9X9Z5 (EMBL:AL079332) (143 aa), Fasta scores: E(): 1.3e-12, 42.3% identity in 137 aa overlap.;UniProt_AC=Q9CBM4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2198693	2198854	.	-	0	Locus=ML1815A;Name=ML1815A;Function=;Product=Possible transcriptional regulatory protein;Comments=ML1815A, len: 162 bp. Possible pseudogene similar to M. tuberculosis Rv1473A (192 bp) (Best blastx score: 99).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2203046	2204013	.	+	0	Locus=ML1820;Name=ML1820;Function=;Product=Possible adenylate cyclase (pseudogene);Comments=ML1820, len: 968 bp. Possible pseudogene similar to the M. tuberculosis adenylate cyclases e.g. Rv1318c, Rv1319c and Rv1320c (Best blastx scores: 265).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2204133	2204295	.	+	0	Locus=ML1820A;Name=ML1820A;Function=;Product=Probable transposase (pseudogene);Comments=ML1820A, len: 163 bp. Possible pseudogene similar to several M. tuberculosis transposases associated with IS6110 (Best blastx scores: 75) and identical to ML1291c, ML1242A, ML0599A, ML0568B from M. leprae.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2205588	2206235	.	+	0	Locus=ML1822;Name=ML1822;Function=;Product=Probable cutinase (pseudogene);Comments=ML1822, len: 648 bp. Possible pseudogene similar to the M. tuberculosis cutinases e.g. cut2|Rv2301, cut4|Rv3452 and cut3|Rv3451 (Best blastx scores: 415).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2507533	2507827	.	-	0	Locus=ML2108c;Name=ML2108c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2108c, len: 295 bp. Possible pseudogene of M. tuberculosis orthologue Rv0918 (477 bp) (Best blastx scores: 147).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2189526	2190488	.	-	0	Locus=ML1809c;Name=ML1809c;Function=;Product=conserved hypothetical protein;Comments=ML1809c, len: 320 aa. Conserved hypothetical protein. Similar to M. tuberculosis Rv1480 SW:YE80_MYCTU (P71761) (317 aa), Fasta scores: E(): 0, 87.5% identity in 311 aa overlap. Contains Pfam match to entry PF01882 DUF58, Protein of unknown function.;UniProt_AC=Q9CBL8;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2194284	2194856	.	-	0	Locus=ML1813c;Name=ML1813c;Function=;Product=POSSIBLE MEMBRANE PROTEIN;Comments=ML1813c, len: 190 aa. Possible membrane protein. Similar to M. tuberculosis hypothetical protein Rv1476 TR:O53167 (EMBL:AL021184) (186 aa), Fasta scores: E(): 0, 78.7% identity in 178 aa overlap.;UniProt_AC=Q9CBL4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2208988	2210131	.	-	0	Locus=ML1824c;Name=ML1824c;Function=;Product=Putative group II intron maturase-related protein (pseudogene);Comments=ML1824c, len: 1144 bp. Possible pseudogene, similar to several maturases e.g. Q9MD87|AF218567 putative maturase from Cryphonectria parasitica (Cheshnut blight fungus) (2334 bp), (blastx scores: 143); and Rv0071|O53616 Putative maturase from M. tuberculosis (705 bp), (blastx scores: 153). Belongs to the LEPREP family of dispersed repeats (see citation below);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2222460	2223127	.	+	0	Locus=ML1834;Name=ML1834;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1834, len: 668 bp. Possible pseudogene of M. tuberculosis orthologue Rv0731c (957 bp) (Best blastx scores: 125).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2224000	2225000	.	-	0	Locus=ML1836c;Name=xylB;Function=;Product=Possible d-xylulose kinase XylB (pseudogene);Comments=ML1836c, len: 1001 bp. Possible pseudogene of M. tuberculosis orthologue xylB|Rv0729 (1347 bp) (Best blastx scores: 417).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2225035	2226016	.	+	0	Locus=ML1837;Name=serA2;Function=;Product=Possible D-3-phosphoglycerate dehydrogenase SerA2 (pseudogene);Comments=ML1837, len: 982 bp. Possible pseudogene of M. tuberculosis orthologue Rv0728c|serA2 (981 bp) (Best blastx scores: 581).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2226096	2226453	.	+	0	Locus=ML1838;Name=fucA;Function=;Product=Possible L-fuculose phosphate aldolase FucA (pseudogene);Comments=ML1838, len: 358 bp. Possible pseudogene of M. tuberculosis orthologue fucA|0727c (657 bp) (Best blastx scores: 229).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2223223	2223906	.	-	0	Locus=ML1835c;Name=ML1835c;Function=;Product=conserved hypothetical protein;Comments=ML1835c, len: 227 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetical protein Rv0730 TR:O53794 (EMBL:AL021958) (242 aa), Fasta scores: E(): 0, 83.5% identity in 218 aa overlap.;UniProt_AC=O33005;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2228987	2229427	.	-	0	Locus=ML1840c;Name=rplO;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L15 RPLO;Comments=ML1840c, len: 146 aa. Probable rplO, 50S ribosomal protein L15. Similar to M. tuberculosis 50S ribosomal protein L15 Rv0723 SW:RL15_MYCTU (P95071) (146 aa), Fasta scores: E(): 0, 81.5% identity in 146 aa overlap. Contains Pfam match to entry PF00256 L15, Ribosomal protein L15. Contains Pfam match to entry PF01305 Ribosomal_L15, Ribosomal protein L15 amino terminal region. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00475 Ribosomal protein L15 signature.;UniProt_AC=O33002;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2229428	2229643	.	-	0	Locus=ML1841c;Name=rpmD;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L30 RPMD;Comments=ML1841c, len: 71 aa. Probable rpmD, 50S ribosomal protein L30. Similar to M. tuberculosis 50S ribosomal protein L30 Rv0722 SW:RL30_MYCTU (Z84395) (65 aa), Fasta scores: E(): 1.1e-21, 89.2% identity in 65 aa overlap. Contains Pfam match to entry PF00327 Ribosomal_L30, Ribosomal protein L30p/L7e.;UniProt_AC=O33001;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2245516	2246911	.	-	0	Locus=ML1866c;Name=ML1866c;Function=;Product=Probable dehydrogenase (pseudogene);Comments=ML1866c, len: 1396 bp. Possible pseudogene of M. tuberculosis orthologue Rv0697 (1440 bp) (Best blastx scores: 550).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2246918	2248130	.	-	0	Locus=ML1867c;Name=ML1867c;Function=;Product=Probable membrane sugar transferase (pseudogene);Comments=ML1867c, len: 1213 bp. Possible pseudogene of M. tuberculosis orthologue Rv0696 (1413 bp) (Best blastx scores: 202).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2301842	2302633	.	-	0	Locus=ML1918c;Name=ML1918c;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN;Comments=ML1918c, len: 263 aa. Probable conserved membrane protein. Similar to M. tuberculosis membrane protein Rv3587c TR:O53572 (EMBL:AL022075) (264 aa), Fasta scores: E(): 0, 77.5% identity in 267 aa overlap. Contains probable transmembrane domain.;UniProt_AC=Q9CBJ2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2242246	2242938	.	-	0	Locus=ML1862c;Name=rplD;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L4 RPLD;Comments=ML1862c, len: 230 aa. Probable rplD, 50S ribosomal protein L4. Similar to M. tuberculosis 50S ribosomal protein L4 Rv0702 SW:RL4_MYCTU (P95050) (223 aa), Fasta scores: E(): 0, 86.7% identity in 218 aa overlap. Contains Pfam match to entry PF00573 Ribosomal_L4, Ribosomal protein L4/L1 family.;UniProt_AC=O32982;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2261460	2262245	.	-	0	Locus=ML1881c;Name=ML1881c;Function=;Product=Probable methyltransferase (pseudogene);Comments=ML1881c, len: 786 bp. Possible pseudogene similar to M. tuberculosis Rv2952 (813 bp) (Best blastx scores: 305). Also similar to ML0130c a possible orthologue of M. tuberculosis Rv2952.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2262426	2262698	.	-	0	Locus=ML1882c;Name=ML1882c;Function=;Product=Probable transcriptional regulatory protein (TetR family) (pseudogene);Comments=ML1882c, len: 273 bp. Possible pseudogene of M. tuberculosis orthologue Rv0681 (591 bp) (Best blastx scores: 194).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2263085	2263379	.	+	0	Locus=ML1883;Name=ML1883;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML1883, len: 295 bp. Possible pseudogene of M. tuberculosis orthologue Rv0680c (375 bp) (Best blastx scores: 154).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2263562	2263911	.	+	0	Locus=ML1884;Name=ML1884;Function=;Product=Conserved hypothetical threonine rich protein (pseudogene);Comments=ML1884, len: 350 bp. Possible pseudogene of M. tuberculosis orthologue Rv0679c (498 bp) (Best blastx scores: 155).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2278448	2279763	.	-	0	Locus=ML1893c;Name=ML1893c;Function=;Product=Probable dioxygenase (pseudogene);Comments=ML1893c, len: 1316 bp. Possible pseudogene of M. tuberculosis orthologue Rv0654 (1506 bp) (Best blastx scores: 240).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2279883	2280351	.	+	0	Locus=ML1894;Name=ML1894;Function=;Product=Possible transcriptional regulatory protein (pseudogene);Comments=ML1894, len: 469 bp. Possible pseudogene of M. tuberculosis orthologue Rv0653c (696 bp) (Best blastx scores: 142).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2360799	2361056	.	+	0	Locus=ML1975;Name=ML1975;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML1975, len: 258 bp. Possible pseudogene similar to several oxidoreductases e.g. Q9RK29|AL132856 probable oxidoreductase SCF15.08C from Streptomyces coelicolor (792 bp) (blastx scores:: 99).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2243607	2243912	.	-	0	Locus=ML1864c;Name=rpsJ;Function=;Product=30S RIBOSOMAL PROTEIN S10 RPSJ (TRANSCRIPTION ANTITERMINATION FACTOR NUSE);Comments=ML1864c, len: 101 aa. Probable rpsJ, 30S ribosomal protein S10. Similar to M. tuberculosis 30S ribosomal protein S10 Rv0700 SW:RS10_MYCTU (P95048) (101 aa), Fasta scores: E(): 0, 97.0% identity in 101 aa overlap. Contains Pfam match to entry PF00338 Ribosomal_S10, Ribosomal protein S10p/S20e. Contains PS00361 Ribosomal protein S10 signature.;UniProt_AC=P30765;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2988601	2988978	.	-	0	Locus=ML2508c;Name=ML2508c;Function=;Product=Possible conserved exported protein (pseudogene);Comments=ML2508c, len: 378 bp. Possible pseudogene of M. tuberculosis orthologue Rv0320 (663 bp) (Best blastx scores: 205).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2280442	2280834	.	-	0	Locus=ML1895c;Name=rplL;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L7/L12 RPLL (SA1);Comments=ML1895c, len: 130 aa. Probable rplL, 50S ribosomal protein L7/L12. Similar to M. tuberculosis 50S ribosomal protein L7/L12 rplL Rv0652 SW:RL7_MYCTU (P37381) (130 aa), Fasta scores: E(): 0, 88.5% identity in 130 aa overlap. Contains Pfam match to entry PF00542 Ribosomal_L12, Ribosomal protein L7/L12 C-terminal domain.;UniProt_AC=P30763;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2269277	2273227	.	-	0	Locus=ML1890c;Name=rpoC;Function=;Product=DNA-DIRECTED RNA POLYMERASE (BETA' CHAIN) RPOC (TRANSCRIPTASE BETA' CHAIN) (RNA POLYMERASE BETA' SUBUNIT).;Comments=ML1890c, len: 1316 aa. Probable rpoC, DNA-directed RNA polymerase, beta' chain (EC 2.7.7.6). Similar to M. tuberculosis DNA-directed RNA polymerase beta chain Rv0668 SW:RPOC_MYCTU (P47769) (1316 aa), Fasta scores: E(): 0, 95.6% identity in 1316 aa overlap, and to many others e.g. Escherichia coli SW:RPOC_ECOLI (P00577) (1407 aa), Fasta scores: E(): 0, 42.5% identity in 1461 aa overlap. Contains Pfam match to entry PF00623 RNA_pol_A, RNA polymerase alpha subunit. Contains Pfam match to entry PF01854 RNA_pol_A2, RNA polymerase A/beta'/A subunit.;UniProt_AC=P30761;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2290316	2291023	.	-	0	Locus=ML1904c;Name=rplA;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L1 RPLA;Comments=ML1904c, len: 235 aa. Probable rplA, 50S ribosomal protein L1. Similar to M. tuberculosis 50S ribosomal protein L1 Rv0641 SW:RL1_MYCTU (P96932) (235 aa), Fasta scores: E(): 0, 93.6% identity in 235 aa overlap. Contains Pfam match to entry PF00687 Ribosomal_L1, L1P family of ribosomal proteins.;UniProt_AC=Q9CBK2;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2313726	2314558	.	+	0	Locus=ML1931;Name=xthA;Function=;Product=Probable exodeoxyribonuclease III protein XthA (pseudogene);Comments=ML1931, len: 833 bp. Possible pseudogene of M. tuberculosis orthologue xthA|Rv0427c (876 bp) (Best blastx scores: 398).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2315486	2319485	.	+	0	Locus=ML1933;Name=ctpH;Function=;Product=Possible metal cation-transporting P-type ATPase CtpH (pseudogene);Comments=ML1933, len: 4000 bp. Possible pseudogene of M. tuberculosis orthologue ctpH|Rv0425c (4620 bp) (Best blastx scores: 523).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2319579	2319818	.	+	0	Locus=ML1934;Name=ML1934;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1934, len: 240 bp. Possible pseudogene of M. tuberculosis orthologue Rv0424c (276 bp) (Best blastx scores: 230).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2320083	2321097	.	-	0	Locus=ML1935c;Name=ML1935c;Function=;Product=PPE-family protein (pseudogene);Comments=ML1935c, len: 1015 bp. Possible pseudogene similar to several M. tuberculosis PPE-family proteins e.g. PPE61|Rv3532, PPE51|Rv3136 and PPE26|Rv1789 (Best blastx scores: 197).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2304314	2305084	.	-	0	Locus=ML1921c;Name=ML1921c;Function=;Product=POSSIBLE HYDROLASE;Comments=ML1921c, len: 256 aa. Possible hydrolase. Similar to several e.g. M. tuberculosis Rv3591c TR:O06157 (EMBL:Z95555) Possible hydrolase (257 aa), Fasta scores: E(): 0, 79.0% identity in 248 aa overlap. And similar to ML2269 from M. leprae.;UniProt_AC=Q9CBI9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2353705	2353803	.	-	0	Locus=ML1969c;Name=ML1969c;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML1969c, len: 99 bp. Possible transposase remnant, similar to Q44454|Z18270 transposase from Agrobacterium tumefaciens (1098 bp), (blastx scores: 93); and to Q9R9U9|AJ245436 transposase tnpa1 from Pseudomonas putida (1065 bp), (blastx scores: 89). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2295163	2295378	.	-	0	Locus=ML1911A;Name=ML1911A;Function=;Product=conserved hypothetical protein;Comments=ML1911A, len: 71 aa. Conserved hypothetical protein. Orthologous to M. tuberculosis Rv0634A but may be pseudogene as Rv0634A is predicted to be 13 aa longer. Also similar to M. tuberculosis Rv1560, sp|Q10771|YF60_MYCTU HYPOTHETICAL 8.2 KDA PROTEIN Rv1560 (72 aa) E(): 0.0025; 47.500% identity in 40 aa overlap;UniProt_AC=;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2294596	2294763	.	-	0	Locus=ML1911c;Name=rpmG2;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L33 RPMG2;Comments=ML1911c, len: 55 aa. Probable rpmG2, 50S ribosomal protein L33 type 2. Similar to M. tuberculosis 50S ribosomal protein L33 type 2 SW:R332_MYCTU (P96925) (55 aa), Fasta scores: E(): 5.5e-24, 92.7% identity in 55 aa overlap. Contains PS00582 Ribosomal protein L33 signature.;UniProt_AC=Q7AQ19,Q9CBJ5;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2335197	2335915	.	-	0	Locus=ML1948c;Name=ML1948c;Function=;Product=probable transmembrane protein (pseudogene);Comments=ML1948c, len: 719 bp. Possible pseudogene similar to M. tuberculosis Rv3645 (Best blastx scores: 178) also similar to the M. tuberculosis Rv1318,  Rv1319 and Rv1320. Also similar to ML0201c a possible orthologue of M. tuberculosis Rv3645.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2377172	2377414	.	-	0	Locus=ML1990c;Name=ML1990c;Function=;Product=Possible membrane protein;Comments=ML1990c, len: 80 aa. Possible membrane protein. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CBG6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2314828	2315241	.	+	0	Locus=ML1932;Name=ML1932;Function=;Product=POSSIBLE TRANSMEMBRANE PROTEIN;Comments=ML1932, len: 137 aa. Possible transmembrane protein. Similar to M. tuberculosis transmembrane protein Rv0426c TR:P96272 (EMBL:Z84724) (147 aa), Fasta scores: E(): 1.6e-22, 60.4% identity in 139 aa overlap.;UniProt_AC=Q9CBI1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2354068	2355211	.	-	0	Locus=ML1970c;Name=ML1970c;Function=;Product=Putative group II intron maturase-related protein (pseudogene);Comments=ML1970c, len: 1144 bp. Possible pseudogene, similar to several maturases e.g. Q9MD87|AF218567 putative maturase from Cryphonectria parasitica (Cheshnut blight fungus) (2334 bp), (blastx scores: 143); and Rv0071|O53616 Putative maturase from M. tuberculosis (705 bp), (blastx scores: 153). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2323420	2324559	.	+	0	Locus=ML1937;Name=ML1937;Function=;Product=probable integral membrane protein;Comments=ML1937, len: 379 aa. Probable integral membrane protein. Similar to M. tuberculosis hypothetical protein Rv1111c TR:O86351 (EMBL:AL021897) (327 aa), Fasta scores: E(): 5.6e-31, 45.7% identity in 374 aa overlap. The N-terminus contains possible membrane spanning hydrophobic domains. Note start changed since original submission.;UniProt_AC=Q9CBI0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2390671	2390925	.	-	0	Locus=ML1999c;Name=ML1999c;Function=;Product=Putative carboxyvinyl-carboxyphosphonate phosphorylmutase (pseudogene);Comments=ML1999c, len: 255 bp. Possible pseudogene similar to part of many carboxyvinyl-carboxyphosphonate phosphorylmutase genes e.g. CPPM_AERPE from Aeropyrum pernix (Blastx scores: 131).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2352625	2352852	.	-	0	Locus=ML1967c;Name=ML1967c;Function=;Product=PPE family protein (pseudogene);Comments=ML1967c, len: 228 bp. Possible pseudogene similar to several M. tuberculosis PPE family proteins e.g. PPE16|Rv1135c, PPE41|Rv2430c, PPE22|Rv1705c, PPE24|Rv1753c etc (Best blastx scores: 108).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2353321	2353506	.	-	0	Locus=ML1968c;Name=ML1968c;Function=;Product=PE family protein (pseudogene);Comments=ML1968c, len: 186 bp. Possible pseudogene similar to several M. tuberculosis PPE family proteins e.g. PE25|Rv2431c, PE13|Rv1195 and PE8|Rv1040c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2344177	2344689	.	-	0	Locus=ML1956c;Name=rplQ;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L17 RPLQ;Comments=ML1956c, len: 170 aa. Probable rplQ, 50S ribosomal protein L17. Similar to M. tuberculosis 50S ribosomal protein L17 rplQ Rv3456c SW:RL17_MYCTU (O06323) (180 aa), Fasta scores: E(): 0, 81.9% identity in 171 aa overlap. Contains Pfam match to entry PF01196 Ribosomal_L17, Ribosomal protein L17.;UniProt_AC=Q9X797;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2410551	2410704	.	-	0	Locus=ML2018c;Name=ML2018c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2018c, len: 154 bp. Possible pseudogene of M. tuberculosis orthologue Rv1898 (309 bp) (Best blastx scores: 80).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2367425	2367892	.	+	0	Locus=ML1983;Name=ML1983;Function=;Product=conserved hypothetical protein;Comments=ML1983, len: 468 aa. Conserved hypothetical protein. Similar to M. tuberculosis gene Rv1919c TR:O53961 (EMBL:AL022020) (154 aa), Fasta scores: E(): 0, 72.8% identity in 151 aa overlap.;UniProt_AC=Q9CBH1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2376742	2377092	.	-	0	Locus=ML1989c;Name=ML1989c;Function=;Product=hypothetical protein;Comments=ML1989c, len: 116 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBG7;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2366604	2366912	.	+	0	Locus=ML1982;Name=ML1982;Function=;Product=Possible membrane protein;Comments=ML1982, len: 102 aa. Possible membrane protein. Some similarity to transport proteins e.g. ATOE_ECOLI|P76460 Escherichia coli short-chain fatty acids transporter (440 aa), Fasta scores: E(): 0.064, (32.7% identity in 55 aa overlap). Contains a hydrophobic membrane spanning region.;UniProt_AC=Q9CBH2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2395793	2396193	.	-	0	Locus=ML2003c;Name=ML2003c;Function=;Product=Probable oxidoreductase dehydrogenase (pseudogene);Comments=ML2003c, len: 401 bp. Possible pseudogene similar to M. tuberculosis Rv3829c (1611 bp) (Best blastx scores: 121).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2396415	2396672	.	+	0	Locus=ML2004;Name=ML2004;Function=;Product=Possible hydrolase (pseudogene);Comments=ML2004, len: 258 bp. Possible pseudogene similar to several M. tuberculosis putative hydrolases e.g. Rv2715 (Best blastx scores: 114).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2396769	2397465	.	+	0	Locus=ML2005;Name=ML2005;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2005, len: 697 bp. Possible pseudogene similar to M. tuberculosis Rv0021c (969 bp) (Best blastx scores: 197).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2398936	2399334	.	+	0	Locus=ML2006;Name=ML2006;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2006, len: 399 bp. Possible pseudogene similar to M. tuberculosis Rv3368c (435 bp) (Best blastx scores: 130). Also similar to ML0418 a possible orthologue of M. tuberculosis Rv3368c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2400382	2400839	.	+	0	Locus=ML2008;Name=furA;Function=;Product=Ferric uptake regulatory protein FurA (pseudogene);Comments=ML2008, len: 458 bp. Possible pseudogene of M. tuberculosis orthologue furA|Rv1909c (453 bp) (Best blastx scores: 118).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2400874	2402892	.	+	0	Locus=ML2009;Name=katG;Function=;Product=Catalase-peroxidase-peroxynitritase T KatG (pseudogene);Comments=ML2009, len: 2019 bp. Possible pseudogene of M. tuberculosis orthologue katG|Rv1908c (2223 bp) (Best blastx scores: 391).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2406049	2407287	.	+	0	Locus=ML2014;Name=nanT;Function=;Product=Probable sialic-acid transport integral membrane protein NanT (pseudogene);Comments=ML2014, len: 1239 bp. Possible pseudogene of M. tuberculosis orthologue nanT|Rv1902c (1269 bp) (Best blastx scores: 578).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2427964	2428263	.	-	0	Locus=ML2037c;Name=glnA3;Function=;Product=Probable glutamine synthase GlnA3 (pseudogene);Comments=ML2037c, len: 300 bp. Possible pseudogene of M. tuberculosis orthologue glnA3|Rv1878 (1353 bp) (Best blastx scores: 129).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2408635	2409822	.	+	0	Locus=ML2016;Name=lipJ;Function=;Product=Probable lignin peroxidase LipJ (pseudogene);Comments=ML2016, len: 1188 bp. Possible pseudogene of M. tuberculosis orthologue lipJ|Rv1900c (1389 bp) (Best blastx scores: 394).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2410032	2410502	.	+	0	Locus=ML2017;Name=lppD;Function=;Product=Possible lipoprotein LppD (pseudogene);Comments=ML2017, len: 471 bp. Possible pseudogene of M. tuberculosis orthologue lppD|Rv1899c (1032 bp) (Best blastx scores: 230).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2402980	2403441	.	+	0	Locus=ML2010;Name=ML2010;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML2010, len: 153 aa. Conserved hypothetical protein, possibly exported protein. Similar to M. tuberculosis hypothetical protein Rv1906c TR:O07726 (EMBL:Z97193) (156 aa), Fasta scores: E(): 2.6e-31, 63.2% identity in 155 aa overlap.;UniProt_AC=O33144;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2405363	2405743	.	-	0	Locus=ML2013c;Name=ML2013c;Function=;Product=hypothetical protein;Comments=ML2013c, len: 126 aa. Hypothetical unknown protein.;UniProt_AC=O33147;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2410790	2411209	.	+	0	Locus=ML2019;Name=ML2019;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2019, len: 420 bp. Possible pseudogene of M. tuberculosis orthologue Rv1897c (432 bp) (Best blastx scores: 256);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2412524	2413592	.	+	0	Locus=ML2021;Name=ML2021;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2021, len: 1069 bp. Possible pseudogene of M. tuberculosis orthologue Rv1894c (1131 bp) (Best blastx scores: 252).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2416476	2416766	.	+	0	Locus=ML2025;Name=ML2025;Function=;Product=alcohol dehydrogenase (pseudogene);Comments=ML2025, len: 291 bp. Possible pseudogene similar to part of several alcohol dehydrogenases e.g. ADH2_EMENI|P54202 Emericella nidulans alcohol dehydrogenase II  (367 aa) (best blastx score: 109).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2417268	2417772	.	+	0	Locus=ML2026;Name=ML2026;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2026, len: 505 bp. Possible pseudogene of M. tuberculosis orthologue Rv1890c (612 bp) (Best blastx scores: 232).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2417829	2418442	.	-	0	Locus=ML2027c;Name=ML2027c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2027c, len: 614 bp. Possible pseudogene of M. tuberculosis orthologue Rv1887 (1143 bp) (Best blastx scores: 238).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2420004	2420554	.	+	0	Locus=ML2029;Name=ML2029;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2029, len: 551 bp. Possible pseudogene of M. tuberculosis orthologue Rv1885c (600 bp) (Best blastx scores: 180).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2421761	2422166	.	+	0	Locus=ML2032;Name=lppE;Function=;Product=Possible conserved lipoprotein LppE (pseudogene);Comments=ML2032, len: 406 bp. Possible pseudogene of M. tuberculosis orthologue lppE|Rv1881c (423 bp) (Best blastx scores: 135).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2422762	2424066	.	+	0	Locus=ML2033;Name=cyp140;Function=;Product=Probable cytochrome p450 140 Cyp140 (pseudogene);Comments=ML2033, len: 1305 bp. Possible pseudogene of M. tuberculosis orthologue Rv1880c|cyp140 (1317 bp) (Best blastx scores: 323).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2424802	2425052	.	+	0	Locus=ML2034;Name=ML2034;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2034, len: 251 bp. Possible pseudogene similar to M. tuberculosis Rv2675c (753 bp) (Best blastx scores: 77). Also similar to ML1046 a possible pseudogene similar to M. tuberculosis Rv2675c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2426745	2427751	.	-	0	Locus=ML2036c;Name=ML2036c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2036c, len: 1007 bp. Possible pseudogene of M. tuberculosis orthologue Rv1879 (1137 bp) (Best blastx scores: 279).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2413651	2414175	.	-	0	Locus=ML2022c;Name=ML2022c;Function=;Product=conserved hypothetical protein;Comments=ML2022c, len: 174 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetical protein Rv1893 TR:O07739 (EMBL:Z97193) (72 aa), Fasta scores: E(): 3e-13, 69.4% identity in 72 aa overlap.;UniProt_AC=Q9CBF9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2414271	2414675	.	-	0	Locus=ML2023c;Name=ML2023c;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML2023c, len: 134 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetical protein Rv1891 TR:O07741 (EMBL:Z97193) (135 aa), Fasta scores: E(): 0, 79.7% identity in 133 aa overlap.;UniProt_AC=Q9X7D3;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2425173	2425436	.	-	0	Locus=ML2035c;Name=ML2035c;Function=;Product=hypothetical protein;Comments=ML2035c, len: 87 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBF6;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2421158	2421613	.	+	0	Locus=ML2031;Name=ML2031;Function=;Product=conserved hypothetical protein;Comments=ML2031, len: 151 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein TR:O07748 (EMBL:Z97193) fasta scores: E(): 0, 76.2% in 151 aa, and to Streptomyces actuosus NSH-OrfB TR:P72384 (EMBL:U75434) fasta scores: E(): 2.5e-08, 34.4% in 125 aa.;UniProt_AC=Q9CBF7;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2434255	2435512	.	+	0	Locus=ML2044;Name=ML2044;Function=;Product=Possible glycosyl hydrolase (pseudogene);Comments=ML2044, len: 1041 bp. Possible pseudogene similar to several glycosyl hydrolases e.g. Q8G5U5 possible cyclomaltodextrinase or neopullalanase from Bifidobacterium longum (best blastx score: 497).;UniProt_AC=Q9CBF4;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2437213	2437530	.	+	0	Locus=ML2047;Name=ML2047;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2047, len: 318 bp. Possible pseudogene similar to M. tuberculosis Rv1991c (345 bp) (Best blastx scores: 129).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2438461	2439063	.	+	0	Locus=ML2049;Name=ML2049;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2049, len: 603 bp. Possible pseudogene of M. tuberculosis orthologue Rv1870c (636 bp) (Best blastx scores: 365).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2439167	2440115	.	+	0	Locus=ML2050;Name=ML2050;Function=;Product=Probable reductase (pseudogene);Comments=ML2050, len: 949 bp. Possible pseudogene of M. tuberculosis orthologue Rv1869c (1236 bp) (Best blastx scores: 450).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2440116	2440451	.	+	0	Locus=ML2051;Name=ML2051;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2051, len: 336 bp. Possible pseudogene of M. tuberculosis orthologue Rv1864c (756 bp) (Best blastx scores: 204).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2440427	2441095	.	+	0	Locus=ML2052;Name=ML2052;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML2052, len: 669 bp. Possible pseudogene of M. tuberculosis orthologue Rv1863c (771 bp) (Best blastx scores: 190).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2444731	2445523	.	-	0	Locus=ML2057c;Name=modB;Function=;Product=Probable molybdenum-transport integral membrane protein ABC transporter ModB (pseudogene);Comments=ML2057c, len: 793 bp. Possible pseudogene of M. tuberculosis orthologue modB|Rv1858 (795 bp) (Best blastx scores: 427).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3015191	3016108	.	-	0	Locus=ML2533c;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML2533c, len: 918 bp. Possible pseudogene of M. tuberculosis orthologue PPE4|Rv0286 (1542 bp) (Best blastx scores: 361). ;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2445553	2446325	.	-	0	Locus=ML2058c;Name=modA;Function=;Product=Probable molybdate-binding lipoprotein ModA (pseudogene);Comments=ML2058c, len: 773 bp. Possible pseudogene of M. tuberculosis orthologue modA|Rv1857 (786 bp) (Best blastx scores: 260).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2447305	2448252	.	+	0	Locus=ML2060;Name=ML2060;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML2060, len: 948 bp. Possible pseudogene of M. tuberculosis orthologue Rv1855c (924 bp) (Best blastx scores: 359).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2450045	2450276	.	-	0	Locus=ML2062c;Name=ML2062c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2062c, len: 232 bp. Possible pseudogene of M. tuberculosis orthologue Rv1847 (423 bp) (Best blastx scores: 84).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2455398	2456700	.	+	0	Locus=ML2067;Name=ML2067;Function=;Product=Conserved hypothetical membrane protein (pseudogene);Comments=ML2067, len: 1303 bp. Possible pseudogene of M. tuberculosis orthologue Rv1842c (Best blastx scores: 692).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2437812	2438069	.	+	0	Locus=ML2048;Name=ML2048;Function=;Product=conserved hypothetical protein;Comments=ML2048, len: 85 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv1871 TR:P95144 (EMBL:AL204060) fasta scores: E(): 4.7e-16, 62.0% in 79 aa, and to Streptomyces coelicolor hypothetical protein TR:CAB88434 (EMBL:AL353815) fasta scores: E(): 0.0092, 39.3% in 61 aa; truncated at C-terminus; may represent a pseudogene.;UniProt_AC=Q7AQ01;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2456700	2457647	.	+	0	Locus=ML2068;Name=ML2068;Function=;Product=Conserved hypothetical membrane protein (pseudogene);Comments=ML2068, len: 948 bp. Possible pseudogene of M. tuberculosis orthologue Rv1841c (1038 bp (Best blastx scores: 512).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2462551	2463353	.	+	0	Locus=ML2071;Name=ML2071;Function=;Product=Possible haloalkane dehalogenase (pseudogene);Comments=ML2071, len: 803 bp. Possible pseudogene of M. tuberculosis orthologue Rv1833c (861 bp) (Best blastx scores: 229).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2578305	2578742	.	-	0	Locus=ML2169c;Name=ML2169c;Function=;Product=Probable fatty-acid-CoA synthetase (pseudogene);Comments=ML2169c, len: 438 bp. Possible pseudogene similar to M. tuberculosis orthologue fadD3|Rv3561 (1524 bp) (Best blastx scores: 124).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2470758	2471082	.	-	0	Locus=ML2079c;Name=ML2079c;Function=;Product=Conserved hypothetical membrane protein (pseudogene);Comments=ML2079c, len: 325 bp. Possible pseudogene of M. tuberculosis orthologue Rv1824 (366 bp) (Best blastx scores: 359).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2460324	2462525	.	+	0	Locus=ML2070;Name=ML2070;Function=;Product=conserved hypothetical protein;Comments=ML2070, len: 733 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 69.7 kda protein Rv1836c SW:YI36_MYCTU (Q50597) fasta scores: E(): 0, 66.0% in 714 aa.;UniProt_AC=Q9CBE8;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2466452	2467147	.	-	0	Locus=ML2073c;Name=ML2073c;Function=;Product=conserved hypothetical protein;Comments=ML2073c, len: 231 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 24.0 kda protein Rv1830 SW:YI30_MYCTU (Q50603) fasta scores: E(): 0, 90.0% in 231 aa, and to Streptomyces coelicolor hypothetical 19.1 kda protein TR:CAB88877 (EMBL:AL353861) fasta scores: E(): 3.7e-30, 64.8% in 145 aa.;UniProt_AC=O32916;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2467380	2467874	.	-	0	Locus=ML2074c;Name=ML2074c;Function=;Product=conserved hypothetical protein;Comments=ML2074c, len: 164 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 18.1 kda protein Rv1829 SW:YI29_MYCTU (Q50604) fasta scores: E(): 0, 95.1% in 164 aa, and to Streptomyces coelicolor conserved hypothetical protein TR:CAB88878 (EMBL:AL353861) fasta scores: E(): 0, 60.9% in 161 aa.;UniProt_AC=O32917;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2467991	2468746	.	-	0	Locus=ML2075c;Name=ML2075c;Function=;Product=conserved hypothetical protein;Comments=ML2075c, len: 251 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 26.4 kda protein Rv1828 SW:YI28_MYCTU (Q50605) fasta scores: E(): 0, 87.6% in 251 aa, and to Streptomyces coelicolor hypothetical 26.5 kda protein TR:CAB88879 (EMBL:AL353861) fasta scores: E(): 1.1e-14, 41.4% in 237 aa.;UniProt_AC=O32918;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2483351	2485298	.	-	0	Locus=ML2089c;Name=ML2089c;Function=;Product=Possible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase and cyclase/dehydrase (pseudogene);Comments=ML2089c, len: 1948 bp. Possible pseudogene of M. tuberculosis orthologue Rv0939 (1935 bp) (Best blastx scores: 341).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2485298	2487357	.	-	0	Locus=ML2090c;Name=ML2090c;Function=;Product=Possible ATP-dependent DNA ligase (pseudogene);Comments=ML2090c, len: 2060 bp. Possible pseudogene of M. tuberculosis orthologue Rv0938 (2280 bp) (Best blastx scores: 431).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2488231	2488863	.	+	0	Locus=ML2092;Name=mku;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2092, len: 633 bp. Possible pseudogene of M. tuberculosis orthologue Rv0937c (822 bp) (Best blastx scores: 333).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2509952	2510864	.	+	0	Locus=ML2109;Name=ML2109;Function=;Product=Possible lipid carrier protein or keto acyl-CoA thiolase (pseudogene);Comments=ML2109, len: 913 bp. Possible pseudogene of M. tuberculosis orthologue Rv0914c (1239 bp) (Best blastx scores: 322).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2510869	2512339	.	+	0	Locus=ML2110;Name=ML2110;Function=;Product=Possible dioxygenase (pseudogene);Comments=ML2110, len: 1471 bp. Possible pseudogene of M. tuberculosis orthologue Rv0913c (1509 bp) (Best blastx scores: 498).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2519547	2520862	.	+	0	Locus=ML2119;Name=accD3;Function=;Product=Putative acetyl-CoA carboxylase carboxyl transferase (beta subunit) accD3 (pseudogene);Comments=ML2119, len: 1316 bp. Possible pseudogene of M. tuberculosis orthologue accD3|Rv0904c (1488 bp) (Best blastx scores: 1142).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2521027	2521374	.	+	0	Locus=ML2120;Name=ML2120;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2120, len: 348 bp. Possible pseudogene similar to several M. tuberculosis conserved hypothetical proteins e.g. Rv1482c, Rv1073, Rv3517 and Rv3714c (Best blastx scores: 90).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2584418	2584591	.	+	0	Locus=ML2173;Name=ML2173;Function=;Product=possible oxidoredutase (pseudogene);Comments=ML2173, len: 204 bp. Possible pseudogene similar to several possible oxidoredutase (Best blastx scores: 102).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2492523	2493297	.	+	0	Locus=ML2096;Name=ML2096;Function=;Product=Probable short-chain dehydrogenase/reductase (pseudogene);Comments=ML2096, len: 775 bp. Possible pseudogene of M. tuberculosis orthologue Rv0927c (792 bp) (Best blastx scores: 352).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2495879	2496853	.	-	0	Locus=ML2099c;Name=nrdZ;Function=;Product=Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (pseudogene);Comments=ML2099c, len: 975 bp. Possible pseudogene of M. tuberculosis orthologue nrdZ|Rv0570 (2079 bp) (Best blastx scores: 274).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2479849	2480992	.	+	0	Locus=ML2086;Name=ML2086;Function=;Product=Putative group II intron maturase-related protein (pseudogene);Comments=ML2086, len: 1144 bp. Possible pseudogene, similar to several maturases e.g. Q9MD87|AF218567 putative maturase from Cryphonectria parasitica (Cheshnut blight fungus) (2334 bp), (blastx scores: 143); and Rv0071|O53616 Putative maturase from M. tuberculosis (705 bp), (blastx scores: 153). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2481257	2481355	.	+	0	Locus=ML2087;Name=ML2087;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML2087, len: 99 bp. Possible transposase remnant, similar to Q44454|Z18270 transposase from Agrobacterium tumefaciens (1098 bp), (blastx scores: 93); and to Q9R9U9|AJ245436 transposase tnpa1 from Pseudomonas putida (1065 bp), (blastx scores: 89). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2496927	2497147	.	-	0	Locus=ML2100c;Name=ML2100c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2100c, len: 221 bp. Possible pseudogene of M. tuberculosis orthologue Rv0569 (267 bp) (Best blastx scores: 68).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2497617	2497907	.	+	0	Locus=ML2101;Name=ML2101;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2101, len: 291 bp. Possible pseudogene similar to M. tuberculosis conserved hypothetical proteins e.g. Rv3134 and Rv2028c (Best blastx scores: 91).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2498692	2499840	.	+	0	Locus=ML2102;Name=ML2102;Function=;Product=Probable hydrolase lipase (pseudogene);Comments=ML2102, len: 1149 bp. Possible pseudogene similar to M. tuberculosis lipD|Rv1923 (1341 bp) (Best blastx scores: 311) and also similar to lipL|Rv1497.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2500779	2501545	.	-	0	Locus=ML2103c;Name=ML2103c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2103c, len: 767 bp. Possible pseudogene of M. tuberculosis orthologue Rv2631 (1299 bp) (Best blastx scores: 259).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2501674	2502006	.	-	0	Locus=ML2104c;Name=ML2104c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2104c, len: 333 bp. Possible pseudogene of M. tuberculosis orthologue Rv2630 (540 bp) (Best blastx scores: 180).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2502414	2503147	.	-	0	Locus=ML2105c;Name=ML2105c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2105c, len: 734 bp. Possible pseudogene of M. tuberculosis orthologue Rv0574c (1143 bp) (Best blastx scores: 197).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2503375	2504642	.	+	0	Locus=ML2106;Name=ML2106;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2106, len: 1268 bp. Possible pseudogene of M. tuberculosis orthologue Rv0571c (1332 bp) (Best blastx scores: 879).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2507112	2507438	.	-	0	Locus=ML2107c;Name=ML2107c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2107c, len: 327 bp. Possible pseudogene of M. tuberculosis orthologue Rv0919 (501 bp) (Best blastx scores: 197).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2522203	2523804	.	+	0	Locus=ML2122;Name=ML2122;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2122, len: 1602 bp. Possible pseudogene similar to M. tuberculosis Rv0785 (1701 bp) (Best blastx scores: 219). Also similar to ML2222 a possible pseudogene similar to M. tuberculosis Rv0785.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2526244	2526630	.	-	0	Locus=ML2125c;Name=ML2125c;Function=;Product=Possible conserved exported or membrane protein (pseudogene);Comments=ML2125c, len: 387 bp. Possible pseudogene of M. tuberculosis orthologue Rv0901 (528 bp) (Best blastx scores: 154).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2526817	2527789	.	-	0	Locus=ML2126c;Name=ompA;Function=;Product=Outer membrane protein A OmpA (pseudogene);Comments=ML2126c, len: 973 bp. Possible pseudogene of M. tuberculosis orthologue ompA|Rv0899 (981 bp) (Best blastx scores: 201).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2528076	2529423	.	+	0	Locus=ML2127;Name=ML2127;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML2127, len: 1348 bp. Possible pseudogene of M. tuberculosis orthologue Rv0897c (1608 bp) (Best blastx scores: 236).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2529434	2530551	.	-	0	Locus=ML2128c;Name=ML2128c;Function=;Product=PPE-family protein (pseudogene);Comments=ML2128c, len: 1118 bp. Possible pseudogene similar to several M. tuberculosis PPE-family proteins e.g. PPE2|Rv0256c, PPE4|Rv0286, PPE3|Rv0280, PPE66|Rv3738c etc (Best blastx scores: 182).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2555760	2556148	.	-	0	Locus=ML2153c;Name=mog;Function=;Product=Probable molybdopterin biosynthesis protein Mog (pseudogene);Comments=ML2153c, len: 389 bp. Possible pseudogene of M. tuberculosis orthologue mog|Rv0865 (483 bp) (Best blastx scores: 218).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2512546	2512980	.	-	0	Locus=ML2111c;Name=ML2111c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2111c, len: 144 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 15.4 kda protein TR:O05904 (EMBL:Z95210) fasta scores: E(): 0, 69.5% in 141 aa.;UniProt_AC=Q50121;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2521547	2521957	.	-	0	Locus=ML2121c;Name=ML2121c;Function=;Product=conserved hypothetical protein;Comments=ML2121c, len: 136 aa. Conserved hypothetical protein. Some similarity to SC5F8.13|AL357613|Q9K4L1 Streptomyces coelicolor putative TetR-family regulator (193 aa), fasta scores: E(): 4.6e-12, (48.5% in 97 aa).;UniProt_AC=O33072;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2513877	2514422	.	-	0	Locus=ML2113c;Name=ML2113c;Function=;Product=conserved hypothetical protein;Comments=ML2113c, len: 181 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 15.8 kda protein Rv0910 TR:O05902 (EMBL:Z95210) fasta scores: E(): 0, 83.9% in 143 aa, and to Mycobacterium tuberculosis hypothetical 15.3 kda protein Rv1546 SW:YF46_MYCTU (Q10780) fasta scores: E(): 1e-19, 38.0% in 142 aa.;UniProt_AC=Q50123;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2547386	2548685	.	+	0	Locus=ML2145;Name=ML2145;Function=;Product=Probable D-alanine, D-serine and glycine transporter (pseudogene);Comments=ML2145, len: 1300 bp. Possible pseudogene similar to M. tuberculosis cycA|Rv1704c (1671 bp) (Best blastx scores: 255).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2575695	2575908	.	-	0	Locus=ML2166c;Name=ML2166c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2166c, len: 214 bp. Possible pseudogene of M. tuberculosis orthologue Rv0854 (444 bp) (Best blastx scores: 131).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2555423	2555751	.	-	0	Locus=ML2152c;Name=moaE2;Function=;Product=Probable molybdenum cofactor biosynthesis protein E2 MoaE2 (pseudogene);Comments=ML2152c, len: 329 bp. Possible pseudogene of M. tuberculosis orthologue moaE2|Rv0866 (426 bp) (Best blastx scores: 146).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2542627	2542902	.	+	0	Locus=ML2141;Name=ML2141;Function=;Product=POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2141, len: 91 aa. Possible conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 9.5 kda protein Rv0879c SW:Y879_MYCTU (Q10541) fasta scores: E(): 6.6e-25, 76.9% in 91 aa. Contains membrane spanning domains.;UniProt_AC=O33059;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2545680	2546168	.	+	0	Locus=ML2144;Name=ML2144;Function=;Product=POSSIBLE CONSERVED EXPORTED PROTEIN;Comments=ML2144, len: 162 aa. Possible conserved exported protein. Similar to Mycobacterium tuberculosis hypothetical 17.8 kda protein Rv0875c precursor SW:Y875_MYCTU (Q10537) fasta scores: E(): 0, 73.5% in 155 aa. Contains a possible N-terminal signal sequence.;UniProt_AC=O33056;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2556173	2556565	.	-	0	Locus=ML2154c;Name=moaC2;Function=;Product=Probable molybdenum cofactor biosynthesis protein C MoaC2 (pseudogene);Comments=ML2154c, len: 393 bp. Possible pseudogene of M. tuberculosis orthologue moaC2|Rv0864 (504 bp) (Best blastx scores: 177).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2562939	2563634	.	-	0	Locus=ML2159c;Name=ML2159c;Function=;Product=Possible cytochrome P450 (pseudogene);Comments=ML2159c, len: 696 bp. Possible pseudogene similar to several M. tuberculosis probable cytochrome P450's e.g. cyp138|Rv0136, cyp137|Rv3685c and cyp139|Rv1666c (Best blastx scores: 82).  Also similar to ML0447 from M. leprae.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2574461	2575455	.	-	0	Locus=ML2165c;Name=far;Function=;Product=Probable fatty-acid-CoA racemase Far (pseudogene);Comments=ML2165c, len: 995 bp. Possible pseudogene of M. tuberculosis orthologue far|Rv0855 (1080 bp) (Best blastx scores: 434).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2586584	2587007	.	+	0	Locus=ML2175;Name=ML2175;Function=;Product=possible membrane protein (pseudogene);Comments=ML2175, len: 424 bp. Possible pseudogene similar to several M. tuberculosis membrane proteins e.g. Rv3728 and Rv3239c (Best blastx scores: 83).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2590100	2590763	.	-	0	Locus=ML2179c;Name=ML2179c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2179c, len: 664 bp. Possible pseudogene similar to M. tuberculosis Rv2308 (717 bp) (Best blastx scores: 240).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2595261	2595696	.	+	0	Locus=ML2180;Name=ML2180;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2180, len: 436 bp. Possible pseudogene of M. tuberculosis orthologue Rv0831c (816 bp) (Best blastx scores: 117).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2598377	2599024	.	+	0	Locus=ML2184;Name=ML2184;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2184, len: 648 bp. Possible pseudogene of M. tuberculosis orthologue Rv0825c (642 bp) (Best blastx scores: 227).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2556723	2556947	.	-	0	Locus=ML2155c;Name=ML2155c;Function=;Product=conserved hypothetical protein;Comments=ML2155c, len: 74 aa. Conserved hypothetical protein. Similar to C-terminus of Mycobacterium tuberculosis hypothetical protein Rv0863 TR:O53875 (EMBL:AL022004) fasta scores: E(): 1.5e-21, 74.0% in 73 aa.;UniProt_AC=Q9CBE2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2561104	2561496	.	-	0	Locus=ML2158c;Name=ML2158c;Function=;Product=hypothetical protein;Comments=ML2158c, len: 130 aa.  Hypothetical unknown protein.;UniProt_AC=Q9CBD9;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2579216	2579440	.	-	0	Locus=ML2170c;Name=ML2170c;Function=;Product=hypothetical protein;Comments=ML2170c, len: 74 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBD5;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2583254	2583610	.	+	0	Locus=ML2172;Name=ML2172;Function=;Product=hypothetical protein;Comments=ML2172, len: 118 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBD4;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2588194	2588451	.	+	0	Locus=ML2176;Name=ML2176;Function=;Product=hypothetical protein;Comments=ML2176, len: 85 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBD2;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2599223	2600239	.	+	0	Locus=ML2185;Name=desA1;Function=CATALYZES THE PRINCIPAL CONVERSION OF SATURATED FATTY ACIDS TO UNSATURATED FATTY ACIDS. THOUGHT TO CONVERT STEAROYL-ACP TO OLEOYL-ACP BY INTRODUCTION OF A CIS DOUBLE BOND BETWEEN CARBONS DELTA-9 AND DELTA-10 OF THE ACYL CHAIN [CATALYTIC ACTIVITY: Stearoyl-[acyl-carrier protein] + AH2 + O2 = oleoyl-[acyl-carrier protein] + A + 2 H2O].;Product=PROBABLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA1 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE) (PROTEIN DES);Comments=ML2185, len: 338 aa. Probable desA1 acyl-[acyl-carrier protein] desaturase (stearoyl-ACP desaturase) (EC 1.14.99.6). Similar to Mycobacterium tuberculosis protein desA1 Rv0824c TR:Q50824 (EMBL:U49839) fasta scores: E(): 0, 79.9% in 338 aa, and to Oryza sativa acyl-[acyl-carrier protein] desaturase precursor SW:STAD_ORYSA (Q40731) fasta scores: E(): 2e-19, 28.3% in 300 aa. Also similar to ML1952 from M. leprae.;UniProt_AC=Q50050;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2609058	2609825	.	-	0	Locus=ML2194c;Name=ML2194c;Function=;Product=Probable transcriptional regulatory protein (pseudogene);Comments=ML2194c, len: 768 bp. Possible pseudogene of M. tuberculosis orthologue Rv0818 (768 bp) (Best blastx scores: 209).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2605136	2605756	.	-	0	Locus=ML2190c;Name=ML2190c;Function=;Product=Probable phosphate-transport integral membrane ABC transporter (pseudogene);Comments=ML2190c, len: 621 bp. Possible pseudogene similar to M. tuberculosis pstA1|Rv0930 (927 bp) (Best blastx scores: 279), also similar to ML2093c a possible orthologue of M. tuberculosis pstA1 ;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2609972	2610823	.	+	0	Locus=ML2195;Name=ML2195;Function=;Product=PROBABLE CONSERVED EXPORTED PROTEIN;Comments=ML2195, len: 283 aa. Probable conserved exported protein. Similar to Mycobacterium tuberculosis exported protein Rv0817c TR:O53829 (EMBL:AL022004) fasta scores: E(): 0, 73.0% in 270 aa. Contains a possible N-terminal signal sequence.;UniProt_AC=Q50040;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2611551	2612036	.	+	0	Locus=ML2197;Name=ML2197;Function=;Product=Possible integral membrane protein;Comments=ML2197, len: 161 aa. Possible integral membrane protein, similar to Q54082|M29612 Saccharopolyspora erythraea hypothetical 16.0 kda protein (149 aa), fasta scores: E(): 4.9e-15, (43.9% in 139 aa). Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q50037;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2610916	2611338	.	+	0	Locus=ML2196;Name=thiX;Function=;Product=PROBABLE THIOREDOXIN THIX;Comments=ML2196, len: 140 aa. Probable thiX, thiredoxin. Similar to Mycobacterium tuberculosis putative thioredoxin Rv0816c TR:O53828 (EMBL:AL022004) fasta scores: E(): 1.1e-30, 63.8% in 141 aa, and to Anacystis nidulans thioredoxin 1 SW:THI1_ANANI (P12243) fasta scores: E(): 9e-07, 37.6% in 93 aa. Also similar to ML2703 from M. leprae. Contains PS00194 Thioredoxin family active site.;UniProt_AC=Q9CBC8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2600283	2601437	.	+	0	Locus=ML2186;Name=ML2186;Function=;Product=POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN;Comments=ML2186, len: 384 aa. Possible transcriptional regulatory protein. Similar to Mycobacterium tuberculosis rv0823c SW:Y823_MYCTU transcriptional regulatory protein (O53835) fasta scores: E(): 0, 82.8% in 396 aa, and to Rhodobacter capsulatus nitrogen regulation protein NifR3 SW:NIR3_RHOCA (Q08111) fasta scores: E(): 2.6e-28, 34.0% in 332 aa. Contains Pfam match to entry PF01207 UPF0034, Uncharacterized protein family UPF0034. Contains PS01136 uncharacterized protein family UPF0034 signature.;UniProt_AC=Q50049;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2631427	2632072	.	+	0	Locus=ML2214;Name=ML2214;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2214, len: 646 bp. Possible pseudogene of M. tuberculosis orthologue Rv0799c (1008 bp) (Best blastx scores: 233).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2632697	2633762	.	+	0	Locus=ML2215;Name=ML2215;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2215, len: 1066 bp. Possible pseudogene similar to M. tuberculosis Rv3627c (1386 bp) (Best blastx scores: 258). Also similar to ML0211 a possible orthologue of M. tuberculosis Rv3627c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2637334	2637723	.	+	0	Locus=ML2221;Name=ML2221;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2221, len: 390 bp. Possible pseudogene of M. tuberculosis orthologue Rv0786c (390 bp) (Best blastx scores: 194).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2637792	2639307	.	-	0	Locus=ML2222c;Name=ML2222c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2222c, len: 1516 bp. Possible pseudogene of M. tuberculosis orthologue Rv0785 (1701 bp) (Best blastx scores: 559). Also similar to ML2122 a possible pseudogene similar to M. tuberculosis Rv0785.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2639390	2639937	.	-	0	Locus=ML2223c;Name=ML2223c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2223c, len: 548 bp. Possible pseudogene of M. tuberculosis orthologue Rv0784 (687 bp) (Best blastx scores: 251).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2870221	2870557	.	+	0	Locus=ML2399;Name=fadA3;Function=;Product=Probable beta-ketoacyl CoA thiolase FadA3 (pseudogene);Comments=ML2399, len: 337 bp. Possible pseudogene of M. tuberculosis orthologue fadA3|Rv1074c (1218 bp) (Best blastx scores: 125).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2619146	2619334	.	+	0	Locus=ML2204;Name=ML2204;Function=;Product=conserved hypothetical protein;Comments=ML2204, len: 62 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 6.9 kda protein Rv0810c TR:O53824 (EMBL:AL022004) fasta scores: E(): 9.9e-17, 77.8% identity in 63 aa, and to Streptomyces coelicolor hypothetical 9.3 kda protein SCD25.24C TR:Q9RKJ8 (EMBL:AL118514) fasta scores: E(): 1.3e-06, 46.8% identity in 62 aa.;UniProt_AC=Q9CBC3;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2640237	2641779	.	+	0	Locus=ML2224;Name=emrB;Function=;Product=Possible multidrug resistance integral membrane efflux protein EmrB (pseudogene);Comments=ML2224, len: 1543 bp. Possible pseudogene of M. tuberculosis orthologue Rv0783c|emrB (1623 bp) (Best blastx scores: 460). Also similar to ML1594c a possible pseudogene similar to M. tuberculosis emrB.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2641817	2642375	.	-	0	Locus=ML2225c;Name=ML2225c;Function=;Product=transcriptional regulatory protein (TetR family) (pseudogene);Comments=ML2225c, len: 559 nt. Possible pseudogene similar to several transcriptional regulators e.g. Q82HG3 Putative TetR-family transcriptional regulator from Streptomyces avermitilis (200 aa) (Best blastx score: 265);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2649932	2650557	.	-	0	Locus=ML2232c;Name=ML2232c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2232c, len: 626 bp. Possible pseudogene of M. tuberculosis orthologue Rv0775 (624 bp) (Best blastx scores: 161).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2650593	2651512	.	+	0	Locus=ML2233;Name=ML2233;Function=;Product=Probable conserved exported protein (pseudogene);Comments=ML2233, len: 920 bp. Possible pseudogene of M. tuberculosis orthologue Rv0774c (912 bp) (Best blastx scores: 391).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2651734	2653213	.	+	0	Locus=ML2234;Name=ggtA;Function=;Product=Probable bifunctional acylase GgtA: cephalosporin acylase and gamma-glutamyl transpeptidase (pseudogene);Comments=ML2234, len: 1480 bp. Possible pseudogene of M. tuberculosis orthologue ggtA|Rv0773c (1539 bp) (Best blastx scores: 208).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2656936	2658278	.	-	0	Locus=ML2238c;Name=phoR;Function=;Product=Possible two component system membrane-associated sensor kinase PhoR (pseudogene);Comments=ML2238c, len: 1343 bp. Possible pseudogene of M. tuberculosis orthologue phoR|Rv0758 (1458 bp) (Best blastx scores: 378).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2658345	2659051	.	-	0	Locus=ML2239c;Name=phoP;Function=;Product=Possible two component system response transcriptional positive regulator PhoP (pseudogene);Comments=ML2239c, len: 707 bp. Possible pseudogene of M. tuberculosis orthologue phoP|Rv0757 (744 bp) (Best blastx scores: 386).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2659233	2659667	.	+	0	Locus=ML2240;Name=ML2240;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2240, len: 435 bp. Possible pseudogene of M. tuberculosis orthologue Rv0756c (726 bp) (Best blastx scores: 180).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2666714	2667001	.	-	0	Locus=ML2243c;Name=ML2243c;Function=;Product=PPE-family protein (pseudogene);Comments=ML2243c, len: 288 bp. Possible pseudogene similar to several M. tuberculosis  PPE-family proteins e.g. PPE57|Rv3459, PPE58|Rv3426 or PPE59|Rv3429.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2667797	2668390	.	-	0	Locus=ML2245c;Name=ML2245c;Function=;Product=Monomeric sarcosine oxidase (pseudogene);Comments=ML2245c, len: 594 bp. Similar to P40854|MSOX_STRSQ Monomeric sarcosine oxidase from Streptomyces sp (1164 bp) (Blastx scores:: 236).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2669339	2670009	.	-	0	Locus=ML2246c;Name=ML2246c;Function=;Product=Probable conserved membrane protein (pseudogene);Comments=ML2246c, len: 671 bp. Possible pseudogene of M. tuberculosis orthologue Rv3482c (783 bp) (Best blastx scores: 128).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2672144	2672692	.	-	0	Locus=ML2248c;Name=ML2248c;Function=;Product=Probable dehydrogenase/reductase (pseudogene);Comments=ML2248c, len: 549 bp. Possible pseudogene similar to M. tuberculosis family of short-chain type dehydrogenases/reductases e.g. Rv3057, FabG3|Rv2002, Rv0712, FabG2|Rv1350 etc (Best blastx scores: 301).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2645997	2646617	.	+	0	Locus=ML2228;Name=ML2228;Function=;Product=POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2228, len: 206 aa. Possible conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 21.6 kda protein cy369.23c precursor Rv0779c OR MTCY369.23C TR:P71833 (EMBL:Z80226) fasta scores: E(): 0, 67.2% identity in 204 aa.;UniProt_AC=O05747;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2673656	2674432	.	-	0	Locus=ML2250c;Name=ML2250c;Function=;Product=Probable short-chain alcohol dehydrogenase/reductase (pseudogene);Comments=ML2250c, len: 777 bp. Possible pseudogene of M. tuberculosis orthologue Rv3485c (945 bp) (Best blastx scores: 284).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2688582	2690085	.	-	0	Locus=ML2266c;Name=fadD8;Function=;Product=Probable fatty-acid-CoA ligase FadD8 (pseudogene);Comments=ML2266c, len: 1504 bp. Possible pseudogene of M. tuberculosis orthologue fadD8|Rv0551c (1716 bp) (Best blastx scores: 345).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2690193	2691798	.	+	0	Locus=ML2267;Name=ML2267;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2267, len: 1606 bp. Possible pseudogene of M. tuberculosis orthologue Rv0552 (1605 bp) (Best blastx scores: 526).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2958132	2958525	.	-	0	Locus=ML2483c;Name=ML2483c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2483c, len: 394 bp. Possible pseudogene of M. tuberculosis orthologue Rv0372c (756 bp) (Best blastx scores: 190);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2676326	2676541	.	-	0	Locus=ML2253c;Name=ML2253c;Function=;Product=conserved hypothetical protein;Comments=ML2253c, len: 71 aa. Conserved hypothetical protein, similar in part to AG84|WAG31|Rv2145c|MTCY270.23|AG84_MYCTU|P46816 Mycobacterium tuberculosis antigen 84 (260 aa), fasta scores: E(): 2.2e-05, 50.0% identity in 54 aa, and to ML0922|AG84|AG84_MYCLE|P46815 Mycobacterium leprae antigen 84, a possible orthologue of M. tuberculosis Rv2145c (266 aa), fasta scores: E(): 5.4e-05, 48.1% identity in 54 aa.;UniProt_AC=Q50166;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2682535	2682837	.	-	0	Locus=ML2258c;Name=ML2258c;Function=;Product=conserved hypothetical protein;Comments=ML2258c, len: 100 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0543c OR MTCY25D10.22C TR:O06409 (EMBL:Z95558) fasta scores: E(): 1.4e-27, 73.5% identity in 98 aa, and to Mycobacterium tuberculosis hypothetical 13.4 kda protein Rv3046c OR MTV012.61C TR:O53292 (EMBL:AL021287) fasta scores: E(): 6.8e-07, 35.9% identity in 103 aa.;UniProt_AC=Q50171;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2698397	2698801	.	-	0	Locus=ML2275c;Name=ML2275c;Function=;Product=Possible benzoquinone methyltransferase (pseudogene);Comments=ML2275c, len: 405 bp. Possible pseudogene of M. tuberculosis orthologue Rv0560c (726 bp) (Best blastx scores: 157).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2706841	2707322	.	-	0	Locus=ML2282c;Name=ML2282c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2282c, len: 482 bp. Possible pseudogene of M. tuberculosis orthologue Rv0566c (492 bp) (Best blastx scores: 377).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2709385	2709931	.	-	0	Locus=ML2285c;Name=ML2285c;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML2285c, len: 547 bp. Possible pseudogene of M. tuberculosis orthologue Rv1986 (600 bp) (Best blastx scores: 161).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2710039	2710847	.	+	0	Locus=ML2286;Name=ML2286;Function=;Product=Probable transcriptional regulatory protein (LysR family) (pseudogene);Comments=ML2286, len: 809 bp. Possible pseudogene of M. tuberculosis orthologue Rv1985c (912 bp) (Best blastx scores: 238).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2711144	2712272	.	-	0	Locus=ML2287c;Name=ML2287c;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML2287c, len: 1129 bp. Possible pseudogene of M. tuberculosis orthologue Rv0575c (1167 bp) (Best blastx scores: 421).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2714203	2715822	.	-	0	Locus=ML2290c;Name=dppD;Function=;Product=Probable dipeptide-transport ATP-binding protein ABC-transporter DppD (pseudogene);Comments=ML2290c, len: 1620 bp. Possible pseudogene of M. tuberculosis orthologue dppD|Rv3663c (1647 bp) (Best blastx scores: 822).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2715865	2716663	.	-	0	Locus=ML2291c;Name=dppC;Function=;Product=Probable dipeptide-transport integral membrane protein ABC-transporter DppC (pseudogene);Comments=ML2291c, len: 799 bp. Possible pseudogene of M. tuberculosis orthologue dppC|Rv3664c (801 bp) (Best blastx scores: 432).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2716770	2717626	.	-	0	Locus=ML2292c;Name=dppB;Function=;Product=Probable dipeptide-transport integral membrane protein ABC transporter DppB (pseudogene);Comments=ML2292c, len: 857 bp. Possible pseudogene of M. tuberculosis orthologue dppB|Rv3665c (927 bp) (Best blastx scores: 601).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2717631	2718114	.	-	0	Locus=ML2293c;Name=dppA;Function=;Product=Probable periplasmic dipeptide-binding lipoprotein DppA (pseudogene);Comments=ML2293c, len: 484 bp. Possible pseudogene of M. tuberculosis orthologue dppA|Rv3666c (1626 bp) (Best blastx scores: 304).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2687465	2688076	.	-	0	Locus=ML2264c;Name=ML2264c;Function=;Product=hypothetical protein;Comments=ML2264c, len: 203 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBB4;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2695510	2696037	.	+	0	Locus=ML2271;Name=ML2271;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2271, len: 175 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis membrane protein Rv0556 or MTCY25D10.35 TR:O06422 (EMBL:Z95558) (171 aa) fasta scores: E(): 0, 79.2% identity in 168 aa. Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CBA9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2698024	2698362	.	-	0	Locus=ML2274c;Name=ML2274c;Function=;Product=POSSIBLE CONSERVED SECRETED PROTEIN;Comments=ML2274c, len: 112 aa. Possible conserved secreted protein. Similar to Mycobacterium tuberculosis putative secreted protein Rv0559c or MTCY25D10.38C TR:O06425 (EMBL:Z95558) (112 aa) fasta scores: E(): 6.3e-32, 69.6% identity in 112 aa. Contains a probable N-terminal signal sequence.;UniProt_AC=Q9CBA7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2718836	2720521	.	+	0	Locus=ML2294;Name=acs;Function=;Product=Probable acetyl-CoA synthetase Acs (pseudogene);Comments=ML2294, len: 1686 bp. Possible pseudogene of M. tuberculosis orthologue acs|Rv3667 (1956 bp) (Best blastx scores: 303).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2708445	2708804	.	+	0	Locus=ML2284;Name=ML2284;Function=;Product=hypothetical protein;Comments=ML2284, len: 119 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBA1;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2713415	2714185	.	-	0	Locus=ML2289c;Name=ML2289c;Function=;Product=conserved hypothetical protein;Comments=ML2289c, len: 256 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv3662c or MTV025.010C TR:O69630 (EMBL:AL022121) (256 aa) fasta scores: E(): 0, 78.0% identity in 255 aa and to Streptomyces coelicolor putative oxidoreductase SCH5.22C TR:Q9X924 (EMBL:AL035636) (274 aa) fasta scores: E(): 1e-11, 40.9% identity in 269 aa.;UniProt_AC=Q9CB99;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2745157	2745445	.	-	0	Locus=ML2317c;Name=ML2317c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2317c, len: 289 bp. Possible pseudogene of M. tuberculosis orthologue Rv3700c (1173 bp) (Best blastx scores: 121).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2958712	2959377	.	+	0	Locus=ML2484;Name=ML2484;Function=;Product=Probable transcriptional regulatory protein (LysR family) (pseudogene);Comments=ML2484, len: 666 bp. Possible pseudogene of M. tuberculosis orthologue Rv0377 (966 bp) (Best blastx scores: 299).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2850490	2850951	.	-	0	Locus=ML2380c;Name=ML2380c;Function=;Product=possible secreted protein;Comments=ML2380c, len: 153 aa. Possible secreted protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0455c TR:O53740 (EMBL:AL021932) (148 aa) fasta scores: E(): 0, 66.4% id in 152 aa. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CB68;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2741820	2743346	.	-	0	Locus=ML2314c;Name=glpK;Function=;Product=PROBABLE GLYCEROL KINASE GLPK (ATP:GLYCEROL 3-PHOSPHOTRANSFERASE)(GLYCEROKINASE) (GK);Comments=ML2314c, len: 508 aa. Probable glpK, glycerol kinase (EC 2.7.1.30). Similar to Mycobacterium tuberculosis glycerol kinase Rv3696c SW:GLPK_MYCTU (O69664) (517 aa) fasta scores: E(): 0, 91.5% identity in 508 aa and Escherichia coli glycerol kinase SW:GLPK_ECOLI (P08859; Q59381) (501 aa) fasta scores: E(): 0, 51.4% id in 500 aa. Contains Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases. Contains PS00445 FGGY family of carbohydrate kinases signature 2. Contains PS00933 FGGY family of carbohydrate kinases signature 1.;UniProt_AC=Q9CB81;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2782755	2782982	.	+	0	Locus=ML2343;Name=ML2343;Function=;Product=Probable L-asparaginase (pseudogene);Comments=ML2343, len: 228 bp. Possible pseudogene similar to M. tuberculosis ansA|Rv1538c (981 bp) (Best blastx scores: 107), also similar to ML1198c a possible orthologue of M. tuberculosis ansA.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2763022	2764401	.	+	0	Locus=ML2333;Name=ML2333;Function=;Product=conserved hypothetical protein;Comments=ML2333, len: 459 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 53.0 kDa protein Rv3719 TR:O69686 (EMBL:AL022121) (470 aa) fasta scores: E(): 0, 82.8% identity in 458 aa.;UniProt_AC=O69516;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2750475	2751485	.	-	0	Locus=ML2321c;Name=ML2321c;Function=;Product=conserved hypothetical protein;Comments=ML2321c, len: 336 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 36.5 kDa protein Rv3707c TR:O69675 (EMBL:AL022121) (336 aa) fasta scores: E(): 0, 81.6% identity in 332 aa, and to Mycobacterium smegmatis hypothetical 35.9 kDa protein in asd 3'region SW:YASD_MYCSM (P41402) (333 aa) fasta scores: E(): 0, 70.8% identity in 332 aa.;UniProt_AC=Q9CB79;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2757748	2758983	.	+	0	Locus=ML2326;Name=ML2326;Function=;Product=possible ligase;Comments=ML2326, len: 411 aa. Possible ligase (EC 6.-.-.-). Similar to several MurCDEF-family proteins e.g. Mycobacterium tuberculosis UDP-N-acetylmuramate--alanine ligase Rv2152c SW:MURC_MYCTU (O06225) (494 aa) fasta scores: E(): 0.0013, 25.6% identity in 387 aa. Also highly similar to Mycobacterium tuberculosis hypothetical 43.4 kDa protein Rv3712 TR:O69679 (EMBL:AL022121) (413 aa) fasta scores: E(): 0, 84.3% id in 413 aa. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family.;UniProt_AC=O69522;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2868744	2869475	.	+	0	Locus=ML2398;Name=ML2398;Function=;Product=Conserved exported protein (pseudogene);Comments=ML2398, len: 732 bp. Possible pseudogene of M. tuberculosis orthologue Rv1075c (945 bp) (Best blastx scores: 209).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2787103	2788008	.	-	0	Locus=ML2346c;Name=ML2346c;Function=;Product=conserved hypothetical protein;Comments=ML2346c, len: 301 aa. Conserved hypothetical protein. Weakly similar to other hypothetical proteins e.g. Q89ZU5 Conserved hypothetical protein from Bacteroides thetaiotaomicron (277 aa), fasta scores: E(): 1.3e-15, (31.319% identity in 182 aa overlap). Note the G+C content of this CDS (54%).;UniProt_AC=Q49942;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2827250	2828463	.	+	0	Locus=ML2362;Name=tcrY;Function=;Product=Possible two component sensor kinase TcrY (pseudogene);Comments=ML2362, len: 1214 bp. Possible pseudogene of M. tuberculosis orthologue Rv3764c|tcrY (1428 bp) (Best blastx scores: 287).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2836814	2837663	.	-	0	Locus=ML2369c;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML2369c, len: 850 bp. Possible pseudogene of M. tuberculosis orthologue  PPE10|Rv0442c (1464 bp) (Best blastx scores: 122).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2839691	2840021	.	-	0	Locus=ML2370c;Name=sigK;Function=;Product=Probable alternative RNA polymerase sigma factor SigK (pseudogene);Comments=ML2370c, len: 331 bp. Possible pseudogene of M. tuberculosis orthologue sigK|Rv0445c (564 bp) (Best blastx scores: 94).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2840695	2841555	.	-	0	Locus=ML2372c;Name=ufaA1;Function=;Product=Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (pseudogene);Comments=ML2372c, len: 861 bp. Possible pseudogene of M. tuberculosis orthologue ufaA1|Rv0447c (1284 bp) (Best blastx scores: 142).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2845418	2846089	.	-	0	Locus=ML2376c;Name=ML2376c;Function=;Product=Possible transcriptional regulatory protein (pseudogene);Comments=ML2376c, len: 672 bp. Possible pseudogene of M. tuberculosis orthologue Rv0452 (711 bp0 (Best blastx scores: 398).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2855475	2855848	.	+	0	Locus=ML2384;Name=ML2384;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2384, len: 374 bp. Possible pseudogene of M. tuberculosis orthologue Rv0459 (492 bp) (Best blastx scores: 192).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2855977	2856218	.	+	0	Locus=ML2385;Name=ML2385;Function=;Product=Conserved hydrophobic protein (pseudogene);Comments=ML2385, len: 242 bp. Possible pseudogene of M. tuberculosis orthologue Rv0460 (240 bp) (Best blastx scores: 182).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2859666	2861320	.	-	0	Locus=ML2389c;Name=ML2389c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2389c, len: 1655 bp. Possible pseudogene of M. tuberculosis orthologue Rv1084 (2022 bp) (Best blastx scores: 325).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2867413	2868277	.	-	0	Locus=ML2397c;Name=ML2397c;Function=;Product=Possible lipase (pseudogene);Comments=ML2397c, len: 865 bp. Possible pseudogene similar to M. tuberculosis lipU|Rv1076 (894 bp) (Best blastx scores: 548), a orthologue of lipU exist in M. leprae at ML0314c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2861307	2861612	.	-	0	Locus=ML2390c;Name=ML2390c;Function=;Product=Conserved membrane protein;Comments=ML2390c, len: 101 aa. Conserved membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv1083 TR:O53431 (EMBL:AL021897) (88 aa) fasta scores: E(): 4.9e-15, 57.4% identity in 101 aa. Contains a possible membrane spanning domain. ;UniProt_AC=Q9CB67;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2811478	2816100	.	-	0	Locus=ML2356c;Name=ppsB;Function=;Product=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB;Comments=ML2356c, len: 1540 aa. Probable ppsB, type-I polyketide synthase. Similar to many polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthesis polyketide synthase Rv2932 SW:PPSB_MYCTU (Q10978; O53234) (1538 aa) fasta scores: E(): 0, 76.3% identity in 1561 aa and Mycobacterium bovis mycocerosic acid synthase SW:MCAS_MYCBO (Q02251) (2110 aa) fasta scores: E(): 0, 42.2% identity in 879 aa. Also similar to ML2353, ML2354, ML0139, ML0135, ML2354, ML2355, ML2357, ML1229 and ML0101 from M. leprae. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q9S384;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	3035417	3036264	.	+	0	Locus=ML2547;Name=ML2547;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2547, len: 848 bp. Possible pseudogene of M. tuberculosis orthologue Rv0269c (1194 bp) (Best blastx scores: 255).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2872838	2873611	.	+	0	Locus=ML2402;Name=echA8;Function=;Product=PROBABLE ENOYL-CoA HYDRATASE ECHA8 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE);Comments=ML2402, len: 257 aa. Probable echA8, enoyl-CoA hydratase (EC 4.2.1.17). Similar to Mycobacterium tuberculosis probable enoyl-CoA hydratase Rv1070c SW:ECH8_MYCTU (O53418) (257 aa) fasta scores: E(): 0, 86.4% identity in 257 aa, and to Rhizobium meliloti probable enoyl-CoA hydratase SW:ECHH_RHIME (Q52995) (257 aa) fasta scores: E(): 0, 67.3% identity in 257 aa. Also similar to ML1724 from M. leprae. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family. Contains PS00166 Enoyl-CoA hydratase/isomerase signature.;UniProt_AC=O07137;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2891481	2892354	.	+	0	Locus=ML2417;Name=ML2417;Function=;Product=Possible conserved membrane protein (pseudogene);Comments=ML2417, len: 874 bp. Possible pseudogene of M. tuberculosis orthologue Rv0519c (903 bp) (Best blastx scores: 337).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2898962	2899255	.	-	0	Locus=ML2423c;Name=ML2423c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2423c, len: 294 bp. Possible pseudogene of M. tuberculosis orthologue Rv0508 (294 bp) (Best blastx scores: 249);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3069804	3070547	.	+	0	Locus=ML2571;Name=ML2571;Function=;Product=Possible glycerophosphoryl diester phosphodiesterase (pseudogene);Comments=ML2571, len: 744 bp. Possible pseudogene similar to M. tuberculosis glpQ2|Rv0317c (771 bp) (Best blastx scores: 338).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2990515	2991103	.	+	0	Locus=ML2509;Name=ML2509;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2509, len: 589 bp. Possible pseudogene similar to M. tuberculosis Rv2826c (885 bp) (Best blastx scores: 189).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3036714	3037430	.	+	0	Locus=ML2548;Name=ML2548;Function=;Product=Probable iron-transport lipoprotein (pseudogene);Comments=ML2548, len: 717 bp. Possible pseudogene of M. tuberculosis orthologue Rv0265c (993 bp) (Best blastx scores: 370).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2890131	2890523	.	-	0	Locus=ML2416A;Name=ML2416A;Function=;Product=Hypothetical protein;Comments=ML2416A, len: 130 aa. Hypothetical protein.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2974125	2974598	.	+	0	Locus=ML2497;Name=ML2497;Function=;Product=hypothetical protein;Comments=ML2497, len: 157 aa. Hypothetical unknown protein.;UniProt_AC=Q9CB22;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	3054595	3054885	.	+	0	Locus=ML2562;Name=ML2562;Function=;Product=hypothetical protein;Comments=ML2562, len: 96 aa. Hypothetical unknown protein.;UniProt_AC=Q9CD23;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2881028	2882656	.	-	0	Locus=ML2410c;Name=ML2410c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2410c, len: 542 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0528  TR:O06394 (EMBL:Z95558) (529 aa) fasta scores: E(): 0, 80.9% identity in 530 aa. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CB62;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2923927	2924459	.	+	0	Locus=ML2448;Name=ML2448;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2448, len: 533 bp. Possible pseudogene of M. tuberculosis orthologue Rv0481c (525 bp) (Best blastx scores: 147).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2920673	2921404	.	+	0	Locus=ML2445;Name=ML2445;Function=;Product=Probable short-chain type oxidoreductase (pseudogene);Comments=ML2445, len: 732 bp. Possible pseudogene of M. tuberculosis orthologue Rv0484c (756 bp) (Best blastx scores: 429).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2906428	2907108	.	-	0	Locus=ML2431c;Name=ML2431c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2431c, len: 681 bp. Possible pseudogene of M. tuberculosis orthologue Rv0499 (876 bp) (Best blastx scores: 235).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2305210	2305527	.	+	0	Locus=ML1922;Name=ML1922;Function=;Product=conserved hypothetical protein TB11.2 homolog;Comments=ML1922, len: 105 aa. Conserved hypothetical protein. Similar to M. tuberculosis conserved hypothetical protein Rv3592 TR:O06156 (EMBL:Z95555) (105 aa), Fasta scores: E(): 0, 84.6% identity in 104 aa overlap, and to others e.g. Bacillus subtilis hypothetical protein SW:YHGC_BACSU (L10630) (166 aa), Fasta scores: E(): 5.2e-06, 40.8% identity in 71 aa overlap.;UniProt_AC=Q9CBI8;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2911959	2912591	.	+	0	Locus=ML2437;Name=ML2437;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2437, len: 633 bp. Possible pseudogene of M. tuberculosis orthologue Rv0493c (990 bp) (Best blastx scores: 121).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3109201	3109707	.	+	0	Locus=ML2605;Name=ML2605;Function=;Product=conserved hypothetical protein;Comments=ML2605, len: 168 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0185 TR:O07429 (EMBL:Z97050) fasta scores: E(): 0, 76.4% identity in 165 aa.;UniProt_AC=O06065;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3039200	3039748	.	+	0	Locus=ML2551;Name=aac;Function=;Product=AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE AAC (AAC(2')-IC);Comments=ML2551, len: 182 aa. aac, aminoglycoside 2'-N-acetyltransferase (EC 2.3.1.-).  Highly similar to several mycobacterial aminoglycoside-resistance determinants e.g. Mycobacterium tuberculosis aminoglycoside 2'-n-acetyltransferase Aac OR Rv0262c SW:AAC2_MYCTU (P95219; P72033) fasta scores: E(): 0, 78.7% identity in 178 aa.;UniProt_AC=Q9CD24;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2195139	2197973	.	+	0	Locus=ML1814;Name=acn;Function=;Product=PROBABLE IRON-REGULATED ACONITATE HYDRATASE ACN (Citrate hydro-lyase) (Aconitase);Comments=ML1814, len: 944 aa. Probable acn, iron-regulated aconitate hydratase (EC 4.2.1.3). Similar to M. tuberculosis aconitate hydratase Rv1475c TR:O53166 (EMBL:AL021184) (943 aa), Fasta scores: E(): 0, 86.8% identity in 948 aa overlap, and to many others e.g. Bacillus subtilis aconitate hydratase SW:ACON_BACSU (P09339) (908 aa), Fasta scores: E(): 0, 51.1% identity in 940 aa overlap. Also similar to ML1685 from M. leprae. Contains 2 Pfam matches to entry PF00330 aconitase, Aconitase family (aconitate hydratase). Contains Pfam match to entry PF00694 Aconitase_C, Aconitase C-terminal domain. Contains PS01244 Aconitase family signature 2. Contains PS00450 Aconitase family signature 1.;UniProt_AC=Q9CBL3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2912665	2912931	.	+	0	Locus=ML2437A;Name=ML2437A;Function=;Product=Conserved hypothetical protein;Comments=ML2437A, len: 267 bp. Possible pseudogene similar to M. tuberculosis Rv0492A (330 bp) (Best blastx scores: 98);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2955114	2956288	.	-	0	Locus=ML2479c;Name=ML2479c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2479c, len: 1175 bp. Possible pseudogene of M. tuberculosis orthologue Rv0368c (1212 bp) (Best blastx scores: 326).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3030294	3031396	.	+	0	Locus=ML2544;Name=ML2544;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2544, len: 1103 bp. Possible pseudogene of M. tuberculosis orthologue Rv0272c (1134 bp) (Best blastx scores: 474).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2882653	2883441	.	-	0	Locus=ML2411c;Name=ccdA;Function=;Product=POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCDA;Comments=ML2411c, len: 262 aa. possible ccdA, cytochrome C-type biogenesis protein. Similar to Mycobacterium tuberculosis cytochrome C-type biogenesis protein Rv0527 TR:O06393 (EMBL:Z95558) (259 aa) fasta scores: E(): 0, 79.0% identity in 262 aa, and to Bacillus subtilis cytochrome C-type biogenesis protein SW:CCDA_BACSU (P45706) (235 aa) fasta scores: E(): 9e-08, 28.9% identity in 242 aa. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q49810;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3215952	3216359	.	+	0	Locus=ML2674;Name=ML2674;Function=;Product=Probable glutamine-transport transmembrane protein ABC transporter (pseudogene);Comments=ML2674, len: 408 bp. Possible pseudogene of M. tuberculosis orthologue Rv2563 (1050 bp) (Best blastx scores: 212) and also similar to Rv0072.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2391324	2393576	.	-	0	Locus=ML2000c;Name=ctpB;Function=;Product=PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB;Comments=ML2000c, len: 750 aa. Probable ctpB, cation-transporter P-type ATPase B (EC 3.6.3.-). Similar to M. tuberculosis cation-transporting ATPase ctpB SW:CTPB_MYCTU (Q10877) (752 aa), Fasta scores: E(): 0, 77.0% identity in 752 aa overlap, and to many others e.g. Bacillus subtilis potential copper-transporting ATPase YVGX SW:ATCU_BACSU (O32220) (803 aa), Fasta scores: E(): 0, 39.8% identity in 744 aa overlap. Also similar to ML1987, ML0747 and ML2671 from M. leprae. Contains Pfam matches to entries PF00403 HMA, Heavy-metal-associated domain and PF00122 E1-E2_ATPase, E1-E2 ATPase. Also contains Prosite hits to PS00013 Prokaryotic membrane lipoprotein lipid attachment site, PS00154 E1-E2 ATPases phosphorylation site, PS01047 Heavy-metal-associated domain and PS01229 Hypothetical cof family signature 2. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=P46840;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3144581	3145051	.	-	0	Locus=ML2629c;Name=ML2629c;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN TB18.5 HOMOLOG;Comments=ML2629c, len: 156 aa. Conserved hypothetical protein. Similar to a number of proteins of undefined function e.g. Mycobacterium tuberculosis Rv0164 (161 aa), fasta scores: E(): 3.8e-47, (76.316% identity in 152 aa overlap).  Also similar to ML0124 from M. leprae.;UniProt_AC=O06090;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3127775	3128658	.	+	0	Locus=ML2619;Name=ML2619;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML2619, len: 884 bp. Possible pseudogene of M. tuberculosis orthologue Rv0205 (1104 bp) (Best blastx scores: 244).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3089691	3090465	.	+	0	Locus=ML2586;Name=fadD5;Function=;Product=Probable fatty-acid-CoA synthase FadD5 (pseudogene);Comments=ML2586, len: 775 bp. Possible pseudogene of M. tuberculosis orthologue fadD5|Rv0166 (165 bp) (Best blastx scores: 184). Also similar to ML2628c a possible pseudogene similar to M. tuberculosis fadD5.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3162742	3163654	.	+	0	Locus=ML2643;Name=ML2643;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML2643, len: 913 bp. Possible pseudogene of M. tuberculosis orthologue Rv0143c (1479 bp) (Best blastx scores: 262).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2065087	2065887	.	-	0	Locus=ML1712c;Name=fixA;Function=;Product=PROBABLE ELECTRON TRANSFER FLAVOPROTEIN (BETA-SUBUNIT) FIXA (BETA-ETF) (ELECTRON TRANSFER FLAVOPROTEIN SMALL SUBUNIT) (ETFSS);Comments=ML1712c, len: 266 aa. Probable fixA (alternate gene name: etfB), electron transfer flavoprotein (beta-subunit). Highly similar to many electron transfer flavoprotein beta-subunits, including: Megasphaera elsdenii SW:ETFB_MEGEL (O85691) (270 aa), Fasta scores: E(): 1.5e-25, 36.1% identity in 274 aa overlap and Mycobacterium tuberculosis Rv3029c SW:ETFB_MYCTU (O53276) (266 aa), Fasta scores: E(): 0, 95.1% identity in 266 aa overlap. Contains Pfam match to entry PF01012 ETF_beta, Electron transfer flavoprotein beta subunit. NOte previously known as eftB.;UniProt_AC=O33095;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3086333	3087142	.	+	0	Locus=ML2584;Name=ML2584;Function=;Product=POSSIBLE METHYLTRANSFERASE (METHYLASE);Comments=ML2584, len: 269 aa. Possible methyltransferase (EC 2.1.1.-). Similar to Mycobacterium tuberculosis hypothetical protein Rv0224c TR:P96406 (EMBL:Z92669) fasta scores: E(): 0, 82.9% identity in 252 aa. Also weakly to several putative methyltransferases e.g. Synechocystis sp sterol-C-methyltransferase TR:P74388 (EMBL:D90914) fasta scores: E(): 7.4e-06, 31.1% identity in 135 aa.;UniProt_AC=O69492;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3165197	3166134	.	-	0	Locus=ML2645c;Name=ML2645c;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML2645c, len: 938 bp. Possible pseudogene of M. tuberculosis orthologue Rv0139 (1023 bp) (Best blastx scores: 248).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2961955	2962152	.	-	0	Locus=ML2488c;Name=ML2488c;Function=;Product=Possible ketoacyl reductase (pseudogene);Comments=ML2488c, len: 198 bp. Possible pseudogene similar to M. tuberculosis Rv1544 (804 bp) (Best blastx scores: 86). Also similar to ML1205 a possible pseudogene similar to M. tuberculosis Rv1544.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2986701	2987418	.	-	0	Locus=ML2506c;Name=udgA;Function=;Product=Probable UDP-glucose 6-dehydrogenase UdgA (pseudogene);Comments=ML2506c, len: 718 bp. Possible pseudogene of M. tuberculosis orthologue udgA|Rv0322 (1332 bp) (Best blastx scores: 398).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2044342	2046219	.	-	0	Locus=ML1696c;Name=ilvB;Function=;Product=PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT) ILVB (ACETOHYDROXY-ACID SYNTHASE);Comments=ML1696c, len: 625 aa. Probable ilvB, acetolactate synthase I large subunit (EC 4.1.3.18). Highly similar to many acetolactate synthases, large subunit, involved in valine and isoleucine biosynthesis, including: Mycobacterium avium SW:ILVB_MYCAV (Q59498) (621 aa), Fasta scores: E(): 0, 82.7% identity in 624 aa overlap and Mycobacterium tuberculosis Rv3003c SW:ILVB_MYCTU (O53250) (618 aa), Fasta scores: E(): 0, 87.1% identity in 627 aa overlap. Contains Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzymes. Contains PS00187 Thiamine pyrophosphate enzymes signature.;UniProt_AC=O33112;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2946640	2947197	.	+	0	Locus=ML2471;Name=ML2471;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2471, len: 558 bp. Possible pseudogene of M. tuberculosis orthologue Rv3755c (600 bp) (Best blastx scores: 319).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1936170	1937039	.	-	0	Locus=ML1612c;Name=lepB;Function=;Product=PROBABLE SIGNAL PEPTIDASE I LEPB (SPASE I) (LEADER PEPTIDASE I).;Comments=ML1612c, len: 289 aa. Probable lepB, signal peptidase I (EC 3.4.21.89). Similar in parts to many proposed signal peptidases e.g. Bacillus subtilis SW:LEPT_BACSU (P71013) (193 aa), Fasta scores: E(): 1.1e-07, 31.0% identity in 226 aa overlap and Mycobacterium tuberculosis Rv2903c SW:LEP_MYCTU (Q1078) (294 aa), Fasta scores: E(): 0, 69.8% identity in 301 aa overlap. Contains a possible membrane spanning hydrophobic domain. Contains 2 Pfam matches to entry PF00461 Peptidase_S26, Signal peptidase I. Contains PS00501 Signal peptidases I serine active site. Contains PS00761 Signal peptidases I signature 3.;UniProt_AC=O33021;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3004598	3005254	.	-	0	Locus=ML2522c;Name=ML2522c;Function=;Product=POSSIBLE CONSERVED EXPORTED PROTEIN;Comments=ML2522c, len: 218 aa. Possible conserved secreted protein. Similar to Mycobacterium tuberculosis exported protein Rv0309 TR:O07236 (EMBL:Z96800) fasta scores: E(): 0, 78.0% identity in 218 aa, and to Streptomyces coelicolor putative secreted protein SCL24.08 TR:CAB76092 (EMBL:AL157956) fasta scores: E(): 2.8e-13, 32.4% identity in 207 aa. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CD38;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2968018	2968799	.	+	0	Locus=ML2492;Name=ML2492;Function=;Product=Probable monooxygenase (pseudogene);Comments=ML2492, len: 782 bp. Possible pseudogene of M. tuberculosis orthologue Rv0385 (1173 bp) (Best blastx scores: 159).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3171332	3172487	.	-	0	Locus=ML2650c;Name=ML2650c;Function=;Product=Conserved hypothetical membrane protein (pseudogene);Comments=ML2650c, len: 1156 bp. Possible pseudogene similar to M. tuberculosis Rv1639c (1470 bp) (Best blastx scores: 321).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3062388	3062867	.	+	0	Locus=ML2567;Name=ML2567;Function=;Product=hypothetical protein;Comments=ML2567, len: 159 aa. Hypothetical unknown protein.;UniProt_AC=Q9CD21;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2948280	2948759	.	+	0	Locus=ML2473;Name=ML2473;Function=;Product=conserved hypothetical protein;Comments=ML2473, len: 159 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv3753c TR:O69720 (EMBL:AL022121) fasta scores: E(): 0, 88.3% identity in 163 aa.;UniProt_AC=Q9CB33;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2349996	2350481	.	+	0	Locus=ML1966;Name=lpqH;Function=;Product=POSSIBLE 19 KDA LIPOPROTEIN ANTIGEN PRECURSOR LPQH;Comments=ML1966, len: 161 aa.  Possible lpqH, Lipoprotein antigen precutsor. Similar to M. tuberculosis 19 kDa lipoprotein antigen precursor lpqH Rv3763. Contains a possible N-terminal signal sequence and a PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9X7A5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2013063	2013911	.	+	0	Locus=ML1669;Name=ML1669;Function=;Product=PROBABLE OXIDOREDUCTASE;Comments=ML1669, len: 282 aa. Probable oxidoreductase of Aldo/keto reductase family. Highly similar to many putative oxidoreductases including: Escherichia coli SW:YQHE_ECOLI (Q46857) (275 aa), Fasta scores: E(): 0, 46.1% identity in 271 aa overlap and Mycobacterium tuberculosis Rv2971 TR:P95124 (EMBL:Z83018) (282 aa), Fasta scores: E(): 0, 79.8% identity in 282 aa overlap. Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family. Contains PS00062 Aldo/keto reductase family signature 2.;UniProt_AC=O69462;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2911089	2911811	.	-	0	Locus=ML2436c;Name=ML2436c;Function=;Product=Probable transcriptional regulatory protein (GntR family) (pseudogene);Comments=ML2436c, len: 723 bp. Possible pseudogene of M. tuberculosis orthologue Rv0494 (729 bp) (Best blastx scores: 276).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2940008	2940689	.	-	0	Locus=ML2466c;Name=ML2466c;Function=;Product=Possible hemolysin-like protein (pseudogene);Comments=ML2466c, len: 682 bp. Possible pseudogene of M. tuberculosis orthologue Rv1085c (729 bp) (Best blastx scores: 150).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2960112	2960948	.	-	0	Locus=ML2486c;Name=ML2486c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2486c, len: 837 bp. Possible pseudogene of M. tuberculosis orthologue Rv0381c (Best blastx scores: 524).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2159152	2160120	.	-	0	Locus=ML1783c;Name=ML1783c;Function=;Product=Possible transcriptional regulatory protein;Comments=ML1783c, len: 322 aa. Possible transcriptional regulatory protein. Similar to M. tuberculosis Rv2258c TR:O53532 (EMBL:AL021925) (353 aa), Fasta scores: E(): 0, 65.2% identity in 273 aa overlap but shorter at N-terminus and frameshifted near C-terminus. Also similar to some C. elegans proteins e.g. TR:O01593 (EMBL:U97004) (365 aa), Fasta scores: E(): 7.5e-17, 25.1% identity in 303 aa overlap. Contains possible HTH motif at aa 7-28 (+3.24 SD). Contains a probable helix-turn-helix motif at aa 7-28 (Score 1191, SD +3.24);UniProt_AC=Q9CBN3;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	3024998	3025453	.	-	0	Locus=ML2538c;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML2538c, len: 456 bp. Possible pseudogene similar to M. tuberculosis PPE-family proteins e.g. Rv0286, Rv0256c, Rv0096 (Best blastx score: 189).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3229149	3229526	.	+	0	Locus=ML2679B;Name=ML2679B;Function=;Product=Hypothetical protein;Comments=ML2679B, len: 125 aa. Hypothetical protein.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2537503	2538528	.	-	0	Locus=ML2135c;Name=ML2135c;Function=;Product=possible transmembrane protein;Comments=ML2135c, len: 341 aa. Possible transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 39.8 kda protein Rv0885 SW:Y885_MYCTU (Q10546) fasta scores: E(): 0, 83.9% in 341 aa, and to Streptomyces coelicolor putative membrane protein TR:Q9XAE8 (EMBL:AL079356) fasta scores: E(): 1.5e-13, 27.1% in 255 aa. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=O33063;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3087225	3088583	.	+	0	Locus=ML2585;Name=ML2585;Function=;Product=Probable aldehyde dehydrogenase (pseudogene);Comments=ML2585, len: 1359 bp. Possible pseudogene of M. tuberculosis orthologue Rv0223c (1464 bp) (Best blastx scores: 581).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2901013	2901513	.	+	0	Locus=ML2425;Name=ML2425;Function=;Product=conserved hypothetical protein;Comments=ML2425, len: 166 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0504c SW:Y504_MYCTU (Q11168) (166 aa) fasta scores: E(): 0, 83.1% identity in 166 aa. Also similar to ML1908 and ML1910 from M. leprae.;UniProt_AC=P54879;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3239192	3239608	.	-	0	Locus=ML2689c;Name=ML2689c;Function=;Product=conserved hypothetical protein;Comments=ML2689c, len: 138 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 15.0 kda protein Rv0049 SW:Y049_MYCTU (P71706) fasta scores: E(): 0, 83.2% in 137 aa.;UniProt_AC=O53130;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2131298	2131621	.	+	0	Locus=ML1756;Name=mmr;Function=INVOLVED IN TRANSPORT OF MULTIDRUGS (TETRAPHENYLPHOSPHONIUM, ERYTHROMYCIN, ETHIDIUM BROMIDE, ACRIFLAVINE, SAFRANIN O, PYRONIN Y, etc) ACROSS THE MEMBRANE (EXPORT): MULTIDRUGS RESISTANCE BY AN EXPORT MECHANISM (CONFERES RESISTANCE TO TOXIC COMPOUNDS BY REMOVING THEM FOR THE CELLS). RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE.;Product=MULTIDRUGS-TRANSPORT INTEGRAL MEMBRANE PROTEIN MMR;Comments=ML1756, len: 107 aa. Probable mmr, integral membrane multidrugs resistance transporter. Highly similar to several multidrug resistance proteins e.g. Escherichia coli quaternary ammonium compound-resistance protein SW: QACE_ECOLI and Mycobacterium tuberculosis Rv3065 SW:YU65_MYCTU (P95094) (107 aa), Fasta scores: E(): 1e-31, 79.0% identity in 105 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00893 DUF7, Integral membrane protein.;UniProt_AC=Q9CBP1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2917380	2917934	.	-	0	Locus=ML2442c;Name=ML2442c;Function=;Product=conserved hypothetical protein;Comments=ML2442c, len: 184 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein  Rv0487 SW:Y487_MYCTU (Q11153) (183 aa) fasta scores: E(): 0, 69.2% identity in 172 aa.;UniProt_AC=P54139;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2927244	2927615	.	-	0	Locus=ML2452c;Name=ML2452c;Function=;Product=hypothetical protein;Comments=ML2452c, len: 123 aa. Conserved hypothetical protein. Similar in part to Mycobacterium tuberculosis hypothetical protein Rv0477 SW:Y477_MYCTU (Q11144) fasta scores: E(): 1.8e-23, 57.3% identity in 110 aa.;UniProt_AC=Q9CB44;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2431991	2432926	.	-	0	Locus=ML2041c;Name=oxyR;Function=;Product=Probable hydrogen peroxide-inducible genes activator OxyR;Comments=ML2041c, len: 311 aa. Probable hydrogen peroxide-inducible genes activator. Highly similar to several mycobacterial hydrogen peroxide-inducible genes activators e.g. P52677|OXYR_MYCAV from M. avium (311 aa), fasta scores: E(): 1.5e-96, (78.710% identity  in 310 aa overlap); and to OXYR_ECOLI|P11721|P22471 from Escherichia coli (305 aa), fasta scores: E(): 8.1e-33, 37.5% in 288 aa. Identical to previously sequenced OXYR_MYCLE|P52678 from  M. leprae probable (311 aa), fasta scores: E(): 0, (100.0% in 311 aa). Also similar to ML2663 from M. leprae. Contains a probable helix-turn-helix motif at aa 23-44 (Score 1404, SD +3.97). Contains Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. Contains PS00044 Bacterial regulatory proteins. Contains 1 HTH lysR-type DNA-binding domain.;UniProt_AC=P52678;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1969135	1969995	.	+	0	Locus=ML1635;Name=panB;Function=;Product=Probable 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB;Comments=ML1635, len: 286 aa. Probable panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11). Highly similar to 3-methyl-2-oxobutanoate hydroxymethyltransferases from Escherichia coli SW:PANB_ECOLI (P31057) (264 aa), Fasta scores: E(): 0, 45.9% identity in 257 aa overlap and Mycobacterium tuberculosis Rv2225 SW:PANB_MYCTU (Q10505) (281 aa), Fasta scores: E(): 0, 82.6% identity in 287 aa overlap. Also similar to ML1718 a possible pseudogene similar to M. tuberculosis panB.;UniProt_AC=Q9CBT0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2952003	2952245	.	+	0	Locus=ML2477;Name=ML2477;Function=;Product=PE-family protein (pseudogene);Comments=ML2477, len: 243 bp. Possible pseudogene similar to several M. tuberculosis PE-family protein e.g. PE34|Rv3746c and PE35|Rv3872.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2957010	2957706	.	-	0	Locus=ML2481c;Name=ML2481c;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML2481c, len: 697 bp. Possible pseudogene of M. tuberculosis orthologue Rv0370c (897 bp) (Best blastx scores: 159).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2524157	2524858	.	+	0	Locus=ML2123;Name=prrA;Function=;Product=TWO COMPONENT RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN PRRA;Comments=ML2123, len: 233 aa. Probable prrA, two-component response regulator. Similar to Mycobacterium tuberculosis probable transcriptional activator protein cy31.31c Rv0903c TR:Q10531 (EMBL:Z73101) fasta scores: E(): 0, 95.7% in 233 aa, and to Pseudomonas syringae transcriptional activator protein copr SW:COPR_PSESM (Q02540) fasta scores: E(): 2.5e-32, 43.6% in 225 aa. Contains Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal. Contains Pfam match to entry PF00072 response_reg, Response regulator receiver domain.;UniProt_AC=Q50136;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	3102336	3102890	.	+	0	Locus=ML2597;Name=ML2597;Function=;Product=PROBABLE CONSERVED MCE ASSOCIATED PROTEIN;Comments=ML2597, len: 184 aa.  Probable conserved Mce associated membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0177 TR:O07421 (EMBL:Z97050) fasta scores: E(): 0, 60.9% identity in 184 aa. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9CD06;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2348340	2349341	.	+	0	Locus=ML1964;Name=rmlB;Function=;Product=dTDP-GLUCOSE 4,6-DEHYDRATASE RMLB;Comments=ML1964, len: 333 aa. Probable rmlB, dTDP-glucose 4,6-dehydratase (EC ). Similar to M. tuberculosis dTDP-glucose 4,6-dehydratase rmlB Rv3464 TR:O06329 (EMBL:Z95390) (331 aa), Fasta scores: E(): 0, 84.0% identity in 331 aa overlap, and to others e.g. Streptococcus pneumoniae DTDP-glucose-4,6-dehydratase cpsN TR:O54611 (EMBL:AF030364) (349 aa), Fasta scores: E(): 0, 59.9% identity in 334 aa overlap. Also similar to ML0204, ML0751, ML1942 and ML2428 from M. leprae. Contains Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase family.;UniProt_AC=Q9CBH7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2472776	2475112	.	-	0	Locus=ML2082c;Name=secA2;Function=;Product=POSSIBLE PREPROTEIN TRANSLOCASE ATPase SECA2;Comments=ML2082c, len: 778 aa. Possible secA2,  preprotein translocase ATPase. Similar to Mycobacterium tuberculosis preprotein translocase secA 2 subunit Rv1821 SW:SEA2_MYCTU (Q50612) fasta scores: E(): 0, 87.0% in 782 aa, and to Bacillus subtilis preprotein translocase secA subunit SW:SECA_BACSU (P28366) fasta scores: E(): 0, 39.9% in 671 aa. Also similar to ML0779 from M. leprae. Contains Pfam match to entry PF01043 SecA_protein, SecA protein, amino terminal region. Contains PS01312 Protein secA signatures.;UniProt_AC=O32922;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1912189	1912677	.	-	0	Locus=ML1586c;Name=mpt53;Function=;Product=Secreted protein Mpt53 (pseudogene);Comments=ML1586c, len: 488 bp. Possible pseudogene of M. tuberculosis orthologue mpt53|Rv2878c (522 bp) (Best blastx scores: 213).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2893256	2893769	.	-	0	Locus=ML2418c;Name=ML2418c;Function=;Product=Possible conserved transmembrane protein (pseudogene);Comments=ML2418c, len: 514 bp. Possible pseudogene of M. tuberculosis orthologue Rv0513 (549 bp) (Best blastx scores: 170).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2919429	2920405	.	-	0	Locus=ML2444c;Name=ML2444c;Function=;Product=Possible transcriptional regulatory protein (NAGC/XYLR repressor family) (pseudogene);Comments=ML2444c, len: 977 bp. Possible pseudogene of M. tuberculosis orthologue Rv0485 (1317 bp) (Best blastx scores: 222).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2929438	2930042	.	-	0	Locus=ML2456c;Name=ML2456c;Function=;Product=Possible conserved transmembrane protein (pseudogene);Comments=ML2456c, len: 605 bp. Possible pseudogene of M. tuberculosis orthologue Rv0473 (1371 bp) (Best blastx scores: 282).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2944210	2944950	.	+	0	Locus=ML2469;Name=proV;Function=;Product=Possible osmoprotectant transport ATP-binding protein ABC transporter ProV (pseudogene);Comments=ML2469, len: 741 bp. Possible pseudogene of M. tuberculosis orthologue proV|Rv3758c (1131 bp) (Best blastx scores: 167).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3002824	3004019	.	-	0	Locus=ML2520c;Name=ML2520c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2520c, len: 1196 bp. Possible pseudogene of M. tuberculosis orthologue Rv0311 (1230 bp) (Best blastx scores: 556).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2937784	2939179	.	+	0	Locus=ML2464;Name=ML2464;Function=;Product=Probable transcriptional regulatory protein (pseudogene);Comments=ML2464, len: 1396 bp. Possible pseudogene of M. tuberculosis orthologue Rv0465c (1425 bp) (Best blastx scores: 434).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2956320	2956864	.	-	0	Locus=ML2480c;Name=ML2480c;Function=;Product=Possible membrane oxidoreductase (pseudogene);Comments=ML2480c, len: 545 bp. Possible pseudogene of M. tuberculosis orthologue Rv0369c (516 bp) (Best blastx scores: 241).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2957693	2958101	.	-	0	Locus=ML2482c;Name=ML2482c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2482c, len: 409 bp. Possible pseudogene of M. tuberculosis orthologue Rv0371c (594 bp) (Best blastx scores: 148).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2939185	2939751	.	+	0	Locus=ML2465;Name=ML2465;Function=;Product=conserved hypothetical protein;Comments=ML2465, len: 188 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 21.3 kda protein Rv0464c TR:O53749 (EMBL:AL021933) fasta scores: E(): 0, 67.4% id in 187 aa.;UniProt_AC=Q9CB37;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3090774	3091577	.	+	0	Locus=ML2587;Name=yrbE1A;Function=;Product=CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE1A;Comments=ML2587, len: 267 aa.  Probable yrbE1A, conserved hypothetical integral membrane protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0167 TR:O07412 (EMBL:Z97050) fasta scores: E(): 0, 88.5% identity in 262 aa. Orthologue of M. tuberculosis YrbE1A (Rv0167). Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CD16;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	3027842	3028280	.	+	0	Locus=ML2541;Name=ML2541;Function=;Product=Possible transcriptional regulatory protein (pseudogene);Comments=ML2541, len: 439 bp. Possible pseudogene of M. tuberculosis orthologue Rv0275c (Best blastx scores: 133).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2900007	2900909	.	+	0	Locus=ML2424;Name=serB1;Function=;Product=POSSIBLE PHOSPHOSERINE PHOSPHATASE SERB1 (PSP) (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSPASE);Comments=ML2424, len: 300 aa. Possible serB1, phosphoserine phosphatase (EC 3.1.3.3). Similar to several including: Mycobacterium tuberculosis phosphoserine phosphatase SerB1 Rv0505c SW:Y505_MYCTU (Q11169) (373 aa) fasta scores: E(): 0, 83.0% identity in 306 aa.;UniProt_AC=Q49823;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2896541	2897497	.	-	0	Locus=ML2421c;Name=hemC;Function=INVOLVED IN PORPHYRIN BIOSYNTHESIS BY THE C5 PATHWAY (AT THE FOURTH STEP). TETRAPOLYMERIZATION OF THE MONOPYRROLE PBG INTO THE HYDROXYMETHYLBILANE PREUROPORPHYRINOGEN IN SEVERAL DISCRETE STEPS [CATALYTIC ACTIVITY: 4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH3].;Product=PROBABLE PORPHOBILINOGEN DEAMINASE HEMC (PBG) (HYDROXYMETHYLBILANE SYNTHASE) (HMBS) (PRE-UROPORPHYRINOGEN SYNTHASE);Comments=ML2421c, len: 318 aa. Probable hemC, porphobilinogen deaminase (EC 4.3.1.8). Similar to Mycobacterium tuberculosis porphobilinogen deaminase Rv0510 SW:HEM3_MYCTU (Q11173) (309 aa) fasta scores: E(): 0, 87.0% identity in 308 aa, and to Escherichia coli porphobilinogen deaminase HemC SW:HEM3_ECOLI (P06983; P78125) (313 aa) fasta scores: E(): 8.4e-30, 42.9% identity in 312 aa. Contains Pfam match to entry PF01379 Porphobil_deam, Porphobilinogen deaminase.;UniProt_AC=Q49808;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2952765	2953154	.	-	0	Locus=ML2478c;Name=ML2478c;Function=;Product=hypothetical protein;Comments=ML2478c, len: 129 aa. Hypothetical unknown protein (doubtful CDS). Weakly similar in part to Q93H20 Probable metallopeptidase from Streptomyces avermitilis (483 aa), fasta scores: E(): 0.0048, (33.010% identity in 103 aa overlap).;UniProt_AC=Q9CB30;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2908016	2909083	.	-	0	Locus=ML2433c;Name=ML2433c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2433c, len: 355 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 33.1 kda protein Rv0497 SW:Y497_MYCTU (Q11162) (310 aa) fasta scores: E(): 4.6e-21, 54.2% identity in 356 aa. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=P54580;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2930926	2931255	.	+	0	Locus=ML2458;Name=ML2458;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2458, len: 330 bp. Possible pseudogene of M. tuberculosis orthologue Rv0471c (489 bp) (Best blastx scores: 123).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2931522	2931902	.	+	0	Locus=ML2458A;Name=ML2458A;Function=;Product=Conserved hypothetical protein;Comments=ML2458A, len: 381 bp. Possible psuedogene similar to M. tuberculosis Rv0470A (Best blastx score: 135).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2935189	2936445	.	-	0	Locus=ML2462c;Name=icl;Function=;Product=Isocitrate lyase Icl (pseudogene);Comments=ML2462c, len: 1257 bp. Possible pseudogene of M. tuberculosis orthologue icl|Rv0467 (1287 bp) (Best blastx scores: 511);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2933084	2933941	.	-	0	Locus=ML2460c;Name=umaA;Function=;Product=Possible mycolic acid synthase UmaA (pseudogene);Comments=ML2460c, len: 858 bp. Possible pseudogene of M. tuberculosis orthologue umaA|Rv0469 (861 bp) (Best blastx scores: 697).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2985842	2985967	.	-	0	Locus=ML2505c;Name=ML2505c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2505c, len: 126 bp. Possible pseudogene of M. tuberculosis orthologue Rv0332 (786 bp) (Best blastx scores: 98).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2945780	2946453	.	+	0	Locus=ML2470;Name=proZ;Function=;Product=Possible osmoprotectant transport integral membrane protein ABC transporter ProZ (pseudogene);Comments=ML2470, len: 674 bp. Possible pseudogene of M. tuberculosis orthologue proZ|Rv3756c (720 bp) (Best blastx scores: 114).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2950647	2950937	.	-	0	Locus=ML2476c;Name=ML2476c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2476c, len: 96 bp. Possible pseudogene similar to several hypothetical proteins e.g.Q9X8J2|YY12_STRCO Streptomyces coelicolor hypothetical protein (106 aa) (best blastx score: 185);UniProt_AC=Q9CB31;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2936759	2937553	.	-	0	Locus=ML2463c;Name=ML2463c;Function=;Product=conserved hypothetical protein;Comments=ML2463c, len: 264 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 30.2 kda protein Rv0466 TR:O53751 (EMBL:AL021933) fasta scores: E(): 0, 87.1% id in 264 aa.;UniProt_AC=Q9CB38;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2942035	2942415	.	-	0	Locus=ML2468c;Name=ML2468c;Function=;Product=hypothetical protein;Comments=ML2468c, len: 126 aa. Hypothetical unknown protein.;UniProt_AC=Q9CB35;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2928125	2928691	.	-	0	Locus=ML2454c;Name=hbhA;Function=REQUIRED FOR EXTRAPULMONARY DISSEMINATION. MEDIATES ADHERENCE TO EPITHELIAL CELLS BY BINDING TO SULFATED GLYCOCONJUGATES PRESENT AT THE SURFACE OF THESE CELLS; BINDS HEPARIN, DEXTRAN SULFATE, FUCOIDAN AND CHONDROITIN SULFATE. PROMOTES HEMAGGLUTINATION OF ERYTHROCYTES OF CERTAIN HOST SPECIES. INDUCES MYCOBACTERIAL AGGREGATION.;Product=IRON-REGULATED HEPARIN BINDING HEMAGGLUTININ HBHA (ADHESIN);Comments=ML2454c, len: 188 aa. Probable hbhA, iron-regulated herapin binding hemagglutinin. Similar to Mycobacterium tuberculosis heparin-binding hemagglutinin Rv0475 TR:O85733 (EMBL:AF074390) fasta scores: E(): 0, 81.4% identity in 199 aa. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CB42;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2976892	2977297	.	+	0	Locus=ML2499;Name=ML2499;Function=;Product=Probable carbon monoxide dehydrogenase (pseudogene);Comments=ML2499, len: 406 bp. Possible pseudogene of M. tuberculosis orthologue Rv0374c (480 bp) (Best blastx scores: 170).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2978855	2979811	.	+	0	Locus=ML2500;Name=ML2500;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2500, len: 957 bp. Possible pseudogene similar to several M. tuberculosis conserved hypothetical proteins e.g. Rv2264c and Rv0312 (Best blastx scores: 77).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2985207	2985584	.	-	0	Locus=ML2504c;Name=ML2504c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2504c, len: 378 bp. Possible pseudogene of M. tuberculosis orthologue Rv0333 (375 bp) (Best blastx scores: 146).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3028987	3029481	.	-	0	Locus=ML2542c;Name=ML2542c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2542c, len: 495 bp. Possible pseudogene of M. tuberculosis orthologue Rv0274 (582 bp) (Best blastx scores: 124).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3029666	3030218	.	+	0	Locus=ML2543;Name=ML2543;Function=;Product=putative transcriptional regulator (pseudogene);Comments=ML2543, len: 553 bp. Possible pseudogene of M. tuberculosis orthologue Rv0273c (621 bp) (Best blastx scores: 132).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3031516	3032316	.	+	0	Locus=ML2545;Name=fadE6;Function=;Product=Probable acyl-CoA dehydrogenase FadE6 (pseudogene);Comments=ML2545, len: 801 bp. Possible pseudogene of M. tuberculosis orthologue fadE6|Rv0271c (2196 bp) (Best blastx scores: 187).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2970888	2971577	.	-	0	Locus=ML2495c;Name=grpE;Function=;Product=PROBABLE GRPE PROTEIN (HSP-70 COFACTOR);Comments=ML2495c, len: 229 aa. Probable grpE protein (Hsp70 cofactor). Similar to Mycobacterium tuberculosis GrpE protein Rv0351 SW:GRPE_MYCTU (P32724; O08379) fasta scores: E(): 0, 68.6% identity in 229 aa, and to Streptomyces coelicolor GrpE protein SW:GRPE_STRCO (Q05562) fasta scores: E(): 3.5e-18, 36.8% identity in 212 aa. Contains Pfam match to entry PF01025 GrpE, GrpE. Contains PS01071 grpE protein signature.;UniProt_AC=Q9CB23;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2991593	2992012	.	+	0	Locus=ML2510;Name=ML2510;Function=;Product=Probable enoyl-CoA hydratase (pseudogene);Comments=ML2510, len: 420 bp. Possible pseudogene similar to several M. tuberculosis probable enoyl-CoA hydratases e.g. echA5|Rv0675, echA8|Rv1070c, echA1|Rv0222 and echA17|Rv3039c (Best blastx scores: 100).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2992637	2993268	.	+	0	Locus=ML2511;Name=ML2511;Function=;Product=Probable sugar-transport integral membrane protein (pseudogene);Comments=ML2511, len: 632 bp. Possible pseudogene similar to M. tuberculosis sugI|Rv3331 (1509 bp) (Best blastx scores: 95). Also similar to ML0690c a possible pseudogene similar to M. tuberculosis sugI.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2993287	2993614	.	+	0	Locus=ML2512;Name=ML2512;Function=;Product=conserved hypothetical protein (pseudogene);Comments=ML2512, len: 328 bp. Possible pseudogene similar to several M. tuberculosis conserved hypothetical ORFs in REP13E12 repeats e.g. Rv3466, rv1588c, Rv2522, (Best blastx scores: 61);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2993620	2994259	.	-	0	Locus=ML2513c;Name=ML2513c;Function=;Product=Secreted immunogenic protein Mpb64/Mpt64 (pseudogene);Comments=ML2513c, len: 640 bp. Possible pseudogene similar to M. tuberculosis mpt64|Rv1980c (687 bp) (Best blastx scores: 136).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2995551	2996849	.	+	0	Locus=ML2515;Name=ML2515;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML2515, len: 1299 bp. Possible pseudogene similar to M. tuberculosis Rv1635c (1671 bp) (Best blastx scores: 264). Also similar to ML1389c a possible orthologue of M. tuberculosis Rv1635c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2997204	2998923	.	-	0	Locus=ML2516c;Name=ML2516c;Function=;Product=Possible beta-1,3-glucanase precursor (pseudogene);Comments=ML2516c, len: 1720 bp. Possible pseudogene of M. tuberculosis orthologue Rv0315 (885 bp) (Best blastx scores: 440). Also similar to ML1973 a possible pseudogene similar to M. tuberculosis Rv0315.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2999110	2999811	.	+	0	Locus=ML2517;Name=ML2517;Function=;Product=Possible conserved membrane protein (pseudogene);Comments=ML2517, len: 702 bp. Possible pseudogene of M. tuberculosis orthologue Rv0314c (663 bp) (Best blastx scores: 174).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3001812	3002629	.	-	0	Locus=ML2519c;Name=ML2519c;Function=;Product=Conserved hypothetical proline and threonine rich protein (pseudogene);Comments=ML2519c, len: 818 bp. Possible pseudogene of M. tuberculosis orthologue Rv0312 (1863 bp) (Best blastx scores: 183).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3004087	3004470	.	+	0	Locus=ML2521;Name=ML2521;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2521, len: 384 bp. Possible pseudogene of M. tuberculosis orthologue Rv0310c (492 bp) (Best blastx scores: 193).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3005487	3005904	.	-	0	Locus=ML2523c;Name=ML2523c;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML2523c, len: 418 bp. Possible pseudogene of M. tuberculosis orthologue Rv0308 (717 bp) (Best blastx scores: 131).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3006114	3006421	.	+	0	Locus=ML2524;Name=ML2524;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2524, len: 308 bp. Possible pseudogene of M. tuberculosis orthologue Rv0307c (483 bp) (Best blastx scores: 101).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3009073	3009159	.	+	0	Locus=ML2526;Name=ML2526;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2526, len: 87 bp. Possible pseudogene of M. tuberculosis orthologue Rv0295c (804 bp) (Best blastx scores: 100).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3007979	3008968	.	+	0	Locus=ML2525;Name=ML2525;Function=;Product=Proable sulfatase (pseudogene);Comments=ML2525, len: 990 bp. Possible pseudogene of M. tuberculosis orthologue Rv0296c (1398 b) (Best blastx scores: 199).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3025572	3026076	.	-	0	Locus=ML2539c;Name=ML2539c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2539c, len: 505 bp. Possible pseudogene of M. tuberculosis orthologue Rv0281 (909 bp) (Best blastx scores: 180).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3026816	3027671	.	-	0	Locus=ML2540c;Name=ML2540c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2540c, len: 856 bp. Possible pseudogene of M. tuberculosis orthologue Rv0276 (921 bp) (Best blastx scores: 333).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2999824	3000216	.	-	0	Locus=ML2518c;Name=ML2518c;Function=;Product=conserved hypothetical protein;Comments=ML2518c, len: 130 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0313 TR:O07240 (EMBL:Z96800) fasta scores: E(): 0, 77.3% identity in 128 aa.;UniProt_AC=Q9CD39;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3014526	3014822	.	-	0	Locus=ML2532c;Name=esxG;Function=;Product=ESAT-6 LIKE PROTEIN ESXG (CONSERVED HYPOTHETICAL PROTEIN TB9.8);Comments=ML2532c, len: 98 aa. Probable esxG, esat-6 like protein. Similar to Mycobacterium tuberculosis Rv0287 esxG, esat-6 like protein (97 aa), fasta scores: E(): 4.2e-24, (76.842% identity in 95 aa overlap).;UniProt_AC=Q9CD32;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3014197	3014487	.	-	0	Locus=ML2531c;Name=esxH;Function=;Product=LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 7 ESXH (10 kDa ANTIGEN) (CFP-7) (PROTEIN TB10.4);Comments=ML2531c, len: 96 aa. Probable esxH, low molecular weight protein antigen 7. Similar to Mycobacterium tuberculosis low molecular weight protein antigen 7 Rv0288 SW:CFP7_MYCTU (O53693) fasta scores: E(): 6.1e-29, 70.5% identity in 95 aa.;UniProt_AC=Q9CD33;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3040719	3044922	.	+	0	Locus=ML2552;Name=narK3;Function=;Product=Probable nitrite extrusion protein NarK3 (pseudogene);Comments=ML2552, len: 4204 bp. Possible pseudogene of M. tuberculosis orthologue narK3|Rv0261c (Best blastx scores: 288).  This pseudo gene appears to bound a perfectly duplicated portion of sequence.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3045299	3045711	.	+	0	Locus=ML2553;Name=ML2553;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2553, len: 413 bp. Possible pseudogene of M. tuberculosis orthologue Rv0258c (456 bp) (Best blastx scores: 273).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3045799	3046081	.	-	0	Locus=ML2554c;Name=nirD;Function=;Product=Probable nitrite reductase small subunit NirD (pseudogene);Comments=ML2554c, len: 283 bp. Possible pseudogene of M. tuberculosis orthologue nirD|Rv0253 (357 bp) (Best blastx scores: 203).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3046140	3048595	.	-	0	Locus=ML2555c;Name=nirB;Function=;Product=Probable nitrite reductase flavoprotein NirB (pseudogene);Comments=ML2555c, len: 2456 bp. Possible pseudogene of M. tuberculosis orthologue nirB|Rv0252 (2562 bp) (Best blastx scores: 292).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3048665	3048970	.	+	0	Locus=ML2556;Name=hsp;Function=;Product=Heat-stress-induced ribosome-binding protein A Hsp (pseudogene);Comments=ML2556, len: 306 bp. Possible pseudogene of M. tuberculosis orthologue hsp|Rv0251c (480 bp) (Best blastx scores: 188).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3049674	3050482	.	+	0	Locus=ML2558;Name=ML2558;Function=;Product=Probable succinate dehydrogenase (pseudogene);Comments=ML2558, len: 809 bp. Possible pseudogene of M. tuberculosis orthologue Rv0249c (822 bp) (Best blastx scores: 298).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3050532	3052355	.	+	0	Locus=ML2559;Name=ML2559;Function=;Product=Probable succinate dehydrogenase (pseudogene);Comments=ML2559, len: 1824 bp. Possible pseudogene of M. tuberculosis orthologue Rv0248c (1941 bp) (Best blastx scores: 750).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3052451	3053095	.	+	0	Locus=ML2560;Name=ML2560;Function=;Product=Probable succinate dehydrogenase (pseudogene);Comments=ML2560, len: 645 bp. Possible pseudogene of M. tuberculosis orthologue Rv0247c (747 bp) (Best blastx scores: 463).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3167447	3168460	.	-	0	Locus=ML2648c;Name=cyp138;Function=;Product=Probable cytochrome p450 138 Cyp138 (pseudogene);Comments=ML2648c, len: 1014 bp. Possible pseudogene of M. tuberculosis orthologue Rv0136|cyp138 (1326 bp) (Best blastx scores: 166).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3049302	3049598	.	+	0	Locus=ML2557;Name=ML2557;Function=;Product=conserved hypothetical protein;Comments=ML2557, len: 98 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0250c TR:O53672 (EMBL:AL021929) fasta scores: E(): 2e-26, 72.6% identity in 95 aa.;UniProt_AC=O69509;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3070538	3071556	.	+	0	Locus=ML2572;Name=ML2572;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML2572, len: 1019 bp. Possible pseudogene of M. tuberculosis orthologue Rv0235c (1449 bp) (Best blastx scores: 292).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3075139	3076034	.	-	0	Locus=ML2574c;Name=nrdB;Function=;Product=Probable ribonucleoside-diphosphate reductase (beta chain) NrdB (pseudogene);Comments=ML2574c, len: 896 bp. Possible pseudogene of M. tuberculosis orthologue nrdB|Rv0233 (945 bp) (Best blastx scores: 384).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3076082	3076404	.	-	0	Locus=ML2575c;Name=ML2575c;Function=;Product=Probable transcriptional regulatory protein (TetR/AcrR family) (pseudogene);Comments=ML2575c, len: 323 bp. Possible pseudogene of M. tuberculosis orthologue Rv0232 (690 bp) (Best blastx scores: 154).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3076541	3076847	.	-	0	Locus=ML2576c;Name=ML2576c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2576c, len: 307 bp. Possible pseudogene of M. tuberculosis orthologue Rv1102c (312 bp) (Best blastx scores: 138).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3077137	3078710	.	-	0	Locus=ML2578c;Name=fadE4;Function=;Product=Probable acyl-CoA dehydrogenase FadE4 (pseudogene);Comments=ML2578c, len: 1574 bp. Possible pseudogene of M. tuberculosis orthologue fadE4|Rv0231 (1707 bp) (Best blastx scores: 445).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3078928	3079868	.	+	0	Locus=ML2579;Name=php;Function=;Product=Probable phosphotriesterase Php (pseudogene);Comments=ML2579, len: 941 bp. Possible pseudogene of M. tuberculosis orthologue Rv0230c|php (981 bp) (Best blastx scores: 317).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3173929	3174417	.	+	0	Locus=ML2652;Name=ML2652;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2652, len: 489 bp. Possible pseudogene of M. tuberculosis orthologue Rv0088 (675 bp) (Best blastx scores: 157).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3176090	3176572	.	+	0	Locus=ML2653;Name=ML2653;Function=;Product=Possible membrane protein (pseudogene);Comments=ML2653, len: 483 bp. Possible pseudogene of M. tuberculosis orthologue Rv0090 (771 bp) (Best blastx scores: 245).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3065276	3065449	.	+	0	Locus=ML2569A;Name=ML2569A;Function=;Product=SMALL SECRETED PROTEIN;Comments=ML2569A, len: 57 aa. Possible small secreted protein. Orthologue of Mycobacterium tuberculosis, Rv0236A|P58240|Y23A_MYCTU Putative secreted protein  (57 aa), fasta scores: E(): 1.8e-18, (89.474% identity in 57 aa overlap).;UniProt_AC=;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3091581	3092450	.	+	0	Locus=ML2588;Name=yrbE1B;Function=;Product=CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE1B;Comments=ML2588, len: 289 aa. Probable yrbE1B, conserved hypothetical integral membrane protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0168 TR:O07413 (EMBL:Z97050) fasta scores: E(): 0, 85.1% identity in 289 aa. Orthologue of M. tuberculosis YrbE1B (Rv0168). Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CD15;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	3081546	3082829	.	+	0	Locus=ML2581;Name=ML2581;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN;Comments=ML2581, len: 427 aa. Probable conserved membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0227c TR:P96409 (EMBL:Z92669) fasta scores: E(): 0, 76.6% identity in 423 aa. Contains a possible N-terminal signal sequence and a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9CD18;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3142545	3143917	.	-	0	Locus=ML2628c;Name=ML2628c;Function=;Product=acyl-CoA synthase (pseudogene);Comments=ML2628c, len: 1373 bp. Possible pseudogene similar to M. tuberculosis fadD5 (Best blastx scores: 184), Also similar to ML2586 a possible pseudogene similar to M. tuberculosis fadD5.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3154968	3155414	.	+	0	Locus=ML2637;Name=fadE2;Function=;Product=Probable acyl-CoA dehydrogenase FadE2 (pseudogene);Comments=ML2637, len: 447 bp. Possible pseudogene of M. tuberculosis orthologue fadE2|Rv0154c (1212 bp) (Best blastx scores: 177).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3159064	3159996	.	-	0	Locus=ML2640c;Name=ML2640c;Function=;Product=conserved hypothetical protein;Comments=ML2640c, len: 310 aa. Conserved hypothetical protein. Highly similar to many Mycobacterium tuberculosis hypothetical proteins e.g. Rv0146 TR:P96823 (EMBL:Z92770) fasta scores: E(): 0, 78.1% identity in 310 aa.;UniProt_AC=Q9CCZ4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3173298	3173615	.	+	0	Locus=ML2651;Name=ML2651;Function=;Product=hypothetical protein;Comments=ML2651, len: 105 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCZ1;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	3161029	3161653	.	-	0	Locus=ML2642c;Name=ML2642c;Function=;Product=Probable transcriptional regulatory protein (tetR family) (pseudogene);Comments=ML2642c, len: 625 bp. Possible pseudogene of M. tuberculosis orthologue Rv0144 (843 bp) (Best blastx scores: 349).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3166260	3166653	.	-	0	Locus=ML2646c;Name=ML2646c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2646c, len: 394 bp. Possible pseudogene of M. tuberculosis orthologue Rv0138 (504 bp) (Best blastx scores: 104).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3196732	3197079	.	+	0	Locus=ML2668;Name=ML2668;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2668, len: 348 bp. Possible pseudogene similar to M. tuberculosis Rv1805c (348 bp) (Best blastx scores: 86). Also similar to ML1535 a possible pseudogene similar to M. tuberculosis Rv1805c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	260507	260906	.	-	0	Locus=ML0194c;Name=PE_PGRS1;Function=;Product=PE-PGRS family-related protein (pseudogene);Comments=ML0194c, len: 400 bp. Possible pseudogene of M. tuberculosis orthologue Rv3653|PE_PGRS61 (588 bp) (Best blastx scores: 94).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3267519	3267662	.	-	0	Locus=ML2713c;Name=rpmH;Function=;Product=50S RIBOSOMAL PROTEIN L34 RPMH;Comments=ML2713c, len: 47 aa. rpmH, 50S ribosomal protein L34. Highly similar to many 50s ribosomal proteins (L34) e.g. Mycobacterium avium SW:RL34_MYCAV (Q9ZB91) (46 aa), Fasta scores: E(): 1.4e-15, 83.0% identity in 47 aa overlap and Mycobacterium tuberculosis Rv3924c SW:RL34_MYCTU (P52829) (47 aa), Fasta scores: E(): 2.1e-18, 91.5% identity in 47 aa overlap. Contains Pfam match to entry PF00468 Ribosomal_L34, Ribosomal protein L34. Contains PS00784 Ribosomal protein L34 signature.;UniProt_AC=P46386;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2934094	2934957	.	-	0	Locus=ML2461c;Name=fadB2;Function=;Product=PROBABLE 3-HYDROXYBUTYRYL-CoA DEHYDROGENASE FADB2 (BETA-HYDROXYBUTYRYL-CoA DEHYDROGENASE) (BHBD);Comments=ML2461c, len: 287 aa. Probable fadB2, 3-hydroxyacyl-CoA dehydrogenas (EC 1.1.1.157). Similar to Mycobacterium tuberculosis putative 3-hydroxyacyl-CoA dehydrogenase Rv0468 TR:O53753 (EMBL:AL021933) fasta scores: E(): 0, 89.5% identity in 287 aa, and to Clostridium acetobutylicum 3-hydroxybutyryl-CoA dehydrogenase SW:HBD_CLOAB (P52041) fasta scores: E(): 0, 43.3% identity in 282 aa. Contains Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase.;UniProt_AC=Q9CB39;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	3239878	3240694	.	+	0	Locus=ML2690;Name=ML2690;Function=;Product=Possible membrane protein (pseudogene);Comments=ML2690, len: 817 bp. Possible pseudogene of M. tuberculosis orthologue Rv0048c (870 bp) (Best blastx scores: 126).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3257506	3258095	.	+	0	Locus=ML2702;Name=ML2702;Function=;Product=Hypothetical alanine rich protein (pseudogene);Comments=ML2702, len: 590 bp. Possible pseudogene of M. tuberculosis orthologue Rv3912 (765 bp) (Best blastx scores: 80);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1255678	1256447	.	-	0	Locus=ML1092c;Name=PE_PGRS3;Function=;Product=PE_PGRS-family protein (pseudogene);Comments=ML1092c, len: 770 bp. Possible pseudogene of M. tuberculosis orthologue PE_PGRS23|Rv1243c (1689 bp) (Best blastx scores: 184).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3097961	3099139	.	+	0	Locus=ML2593;Name=lprK;Function=;Product=POSSIBLE MCE-FAMILY LIPOPROTEIN LPRK (MCE-FAMILY LIPOPROTEIN MCE1E);Comments=ML2593, len: 392 aa. Possible lprK, Mce-family lipoprotein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0173 TR:O07417 (EMBL:Z97050) fasta scores: E(): 0, 76.3% identity in 389 aa. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Orthologue of M. tuberculosis lprK (mce1E, Rv0173). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CD10;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3216470	3217086	.	+	0	Locus=ML2675;Name=glnQ;Function=;Product=Probable glutamine-transport ATP-binding protein ABC transporte GlnQ (pseudogene);Comments=ML2675, len: 617 bp. Possible pseudogene of M. tuberculosis orthologue glnQ|Rv2564 (993 bp) (Best blastx scores: 312) and also similar to Rv0073.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3103594	3104619	.	-	0	Locus=ML2599c;Name=lprO;Function=;Product=Possible lipoprotein LprO (pseudogene);Comments=ML2599c, len: 1026 bp. Possible pseudogene of M. tuberculosis orthologue lprO|Rv0179c (1110 bp) (Best blastx scores: 158).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3106136	3106797	.	-	0	Locus=ML2601c;Name=ML2601c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2601c, len: 662 bp. Possible pseudogene of M. tuberculosis orthologue Rv0181c (735 bp) (Best blastx scores: 140).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3193715	3193969	.	-	0	Locus=ML2666c;Name=ML2666c;Function=;Product=hypothetical protein;Comments=ML2666c, len: 84 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCY7;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	3108455	3109204	.	+	0	Locus=ML2604;Name=ML2604;Function=;Product=conserved hypothetical protein;Comments=ML2604, len: 249 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 26.8 kda protein Rv0184 TR:O07428 (EMBL:Z97050) fasta scores: E(): 0, 81.9% identity in 249 aa.;UniProt_AC=Q9CD02;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3010280	3011707	.	-	0	Locus=ML2528c;Name=mycP3;Function=;Product=PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3);Comments=ML2528c, len: 475 aa. Probable mycP3, membrane-anchored mycosin (EC 3.4.21.-). Similar to many proposed proteases e.g. Mycobacterium tuberculosis putative protease Rv0291 TR:O53695 (EMBL:AL021930) fasta scores: E(): 0, 69.9% id in 468 aa. Also similar to ML0041 and ML1538 from M. leprae. Contains 2 Pfam matches to entry PF00082 Peptidase_S8, Subtilase family. Contains PS00137 Serine proteases.;UniProt_AC=Q9CD36;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2914497	2915093	.	-	0	Locus=ML2439c;Name=regX3;Function=;Product=TWO COMPONENT SENSORY TRANSDUCTION PROTEIN REGX3 (TRANSCRIPTIONAL REGULATORY PROTEIN) (PROBABLY LUXR-FAMILY);Comments=ML2439c, len: 198 aa. regX3, response regulator protein (sensory transduction protein). Similar to Synechococcus sp alkaline phosphatase synthesis transcriptional regulatory protein SphR SW:SPHR_SYNP7 (P39663) (257 aa) fasta scores: E(): 6.6e-33, 47.1% identity in 206 aa, and to Mycobacterium tuberculosis sensory transduction protein RegX3 Rv0491 SW:RGX3_MYCTU (Q11156) (227 aa) fasta scores: E(): 0, 95.9% identity in 197 aa. Also similar to ML0773, ML0174 and ML2123 from M. leprae. Contains Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal. Contains Pfam match to entry PF00072 response_reg, Response regulator receiver domain.;UniProt_AC=P54884;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	3137850	3138098	.	+	0	Locus=ML2625;Name=fadD4;Function=;Product=Probable fatty-acid-CoA synthase FadD4 (pseudogene);Comments=ML2625, len: 249 bp. Possible pseudogene of M. tuberculosis orthologue fadD4|Rv0214 (1614 bp) (Best blastx scores: 231).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3187869	3189304	.	+	0	Locus=ML2662;Name=oxcA;Function=;Product=Probable oxalyl-CoA decarboxylase OxcA (pseudogene);Comments=ML2662, len: 1436 bp. Possible pseudogene of M. tuberculosis orthologue oxcA|Rv0118c (1749 bp) (Best blastx scores: 220).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3106891	3107607	.	-	0	Locus=ML2602c;Name=sigG;Function=;Product=Probable alternative RNA polymerase sigma subunit factor SigG (pseudogene);Comments=ML2602c, len: 717 bp. Possible pseudogene of M. tuberculosis orthologue sigG|Rv0182c (1113 bp) (Best blastx scores: 149).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3139468	3139984	.	-	0	Locus=ML2626c;Name=fadE3;Function=;Product=Probable acyl-CoA dehydrogenase FadE3 (pseudogene);Comments=ML2626c, len: 517 bp. Possible pseudogene of M. tuberculosis orthologue fadE3|Rv0215c (1074 bp) (Best blastx scores: 159). Also similar to ML1179 a possible pseudogene similar to M. tuberculosis fadE3.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3160315	3160872	.	-	0	Locus=ML2641c;Name=ML2641c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2641c, len: 558 bp. Possible pseudogene of M. tuberculosis orthologue Rv0145 (954 bp) (Best blastx scores: 240).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3163937	3164219	.	+	0	Locus=ML2644;Name=ML2644;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2644, len: 283 bp. Possible pseudogene of M. tuberculosis orthologue Rv0141c (411 bp) (Best blastx scores: 119);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3213371	3214600	.	+	0	Locus=ML2673;Name=ML2673;Function=;Product=Two component sensor histidine kinase (pseudogene);Comments=ML2673, len: 1230 bp. Possible pseudogene similar to M. tuberculosis orthologue Rv0902c|prrB (1341 bp) (Best blastx scores: 369).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3243531	3244340	.	+	0	Locus=ML2694;Name=ML2694;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML2694, len: 810 bp. Possible pseudogene of M. tuberculosis orthologue Rv0044c (795 bp) (Best blastx scores: 394).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3242604	3243503	.	+	0	Locus=ML2693;Name=ML2693;Function=;Product=Possible hydrolase (pseudogene);Comments=ML2693, len: 900 bp. Possible pseudogene of M. tuberculosis orthologue Rv0045c (897 bp) (Best blastx scores: 228).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1684766	1685402	.	+	0	Locus=ML1403;Name=PE_PGRS4;Function=;Product=PE-PGRS family protein (pseudogene);Comments=ML1403, len: 637 bp. Possible pseudogene of M. tuberculosis orthologue PE_PGRS30|Rv1651c (3036 bp) (Best blastx scores: 230).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3228566	3229135	.	+	0	Locus=ML2679A;Name=ML2679A;Function=;Product=Hypothetical protein;Comments=ML2679A, len: 189 aa. Hypothetical protein.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	3219527	3219880	.	-	0	Locus=ML2675A;Name=ML2675A;Function=;Product=Hypothetical protein;Comments=ML2675A, len: 117 aa. Hypothetical protein.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	3150514	3151129	.	-	0	Locus=ML2633c;Name=ML2633c;Function=;Product=Probable transcriptional regulatory protein (TetR/AcrR family) (pseudogene);Comments=ML2633c, len: 616 bp. Possible pseudogene of M. tuberculosis orthologue Rv0158 (645 bp) (Best blastx scores: 272).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3151318	3151431	.	+	0	Locus=ML2633A;Name=ML2633A;Function=;Product=HYPOTHETICAL PROTEIN (pseudogene);Comments=ML2633A, len: 114 bp. Possible pseudogene similar to M. tuberculosis orthologue Rv0157A (129 bp) (Best blastx scores: 159).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3191593	3191913	.	+	0	Locus=ML2665;Name=ML2665;Function=;Product=Probable peptide synthetase (pseudogene);Comments=ML2665, len: 321 bp. Possible pseudogene similar to M. tuberculosis nrp|Rv0101 (7539 bp) (Best blastx scores: 114). Also similar to ML1996 a possible orthologue of M. tuberculosis nrp.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3234599	3234855	.	-	0	Locus=ML2686c;Name=ML2686c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2686c, len: 257 bp. Possible pseudogene of M. tuberculosis orthologue Rv0052 (564 bp) (Best blastx scores: 74).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3133980	3134968	.	+	0	Locus=ML2623;Name=ML2623;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2623, len: 989 bp. Possible pseudogene of M. tuberculosis orthologue Rv0210 (1479 bp) (Best blastx scores: 168).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3220869	3221603	.	-	0	Locus=ML2676c;Name=ML2676c;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML2676c, len: 735 bp. Possible pseudogene of M. tuberculosis orthologue Rv0077c (831 bp) (Best blastx scores: 201).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3232122	3232582	.	-	0	Locus=ML2681c;Name=ML2681c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML2681c, len: 461 bp. Possible pseudogene of M. tuberculosis orthologue Rv0057 (522 bp) (Best blastx scores: 166).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3256950	3257105	.	+	0	Locus=ML2701;Name=sigM;Function=;Product=Possible alternative RNA polymerase sigma factor sigM (pseudogene);Comments=ML2701, len: 156 bp. Possible pseudogene of M. tuberculosis orthologue sigM|Rv3911 (669 bp) (Best blastx scores: 88).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3266789	3267109	.	-	0	Locus=ML2711c;Name=ML2711c;Function=;Product=Possible hemolysin (pseudogene);Comments=ML2711c, len: 321 bp. Possible pseudogene of M. tuberculosis orthologue Rv3922c (363 bp) (Best blastx scores: 369).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3197436	3197756	.	+	0	Locus=ML2669;Name=ML2669;Function=;Product=hypothetical protein;Comments=ML2669, len: 106 aa. Hypothetical protein. Weakly similar in part to Q89MG4 Bll4229 protein from Bradyrhizobium japonicum (221 aa), fasta scores: E(): 0.011, (35.135% identity in 74 aa overlap).;UniProt_AC=Q9ZBE4;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	3264991	3265572	.	-	0	Locus=ML2709c;Name=ML2709c;Function=;Product=conserved hypothetical protein;Comments=ML2709c, len: 193 aa. conserved hypothetical protein similar to several JAG proteins. Similar to Mycobacterium paratuberculosis hypothetical 20.1 kda protein TR:AAF33691 (EMBL:AF222789) fasta scores: E(): 0, 76.0% in 183 aa, and to Mycobacterium tuberculosis hypothetical 20.6 kda protein Rv3920c TR:O53598 (EMBL:AL021426) fasta scores: E(): 0, 73.1% in 193 aa. Contains Pfam match to entry PF01424 R3H, R3H domain.;UniProt_AC=Q50204;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3109773	3110967	.	+	0	Locus=ML2606;Name=bglS;Function=;Product=Probable beta-glucosidase BglS (pseudogene);Comments=ML2606, len: 1195 bp. Possible pseudogene of M. tuberculosis orthologue bglS|Rv0186 (2076 bp) (Best blastx scores: 408).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3112058	3112687	.	-	0	Locus=ML2607c;Name=ML2607c;Function=;Product=polyketide synthase (pseudogene);Comments=ML2607c, len: 630 bp. Possible pseudogene similar to Mycobacterium tuberculosis polyketide synthase Rv3800c|pks13|O53579|AL022076. Also similar to ML0101 a possible orthologue of M. tuberculosis pks13.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3115280	3115739	.	+	0	Locus=ML2610;Name=ML2610;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML2610, len: 460 bp. Possible pseudogene of M. tuberculosis orthologue Rv0191 (1242 bp) (Best blastx scores: 133).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3116035	3116789	.	+	0	Locus=ML2611;Name=ML2611;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2611, len: 755 bp. Possible pseudogene of M. tuberculosis orthologue Rv0192 (1101 bp) (Best blastx scores: 190).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3117044	3118778	.	+	0	Locus=ML2612;Name=ML2612;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML2612, len: 1735 bp. Possible pseudogene of M. tuberculosis orthologue Rv0197 (2289 bp) (Best blastx scores: 496).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3114791	3115198	.	+	0	Locus=ML2609;Name=ML2609;Function=;Product=conserved hypothetical protein;Comments=ML2609, len: 135 aa. Conserved hypothetical protein. Similar in parts to several proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv0190 TR:O07434 (EMBL:Z97050) fasta scores: E(): 6.6e-27, 82.6% identity in 92 aa.;UniProt_AC=O06070;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3120837	3121511	.	+	0	Locus=ML2614;Name=ML2614;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN;Comments=ML2614, len: 224 aa. Probable conserved membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0199 TR:O53650 (EMBL:AL021928) fasta scores: E(): 0, 67.6% identity in 219 aa. Contains possible membrane spanning hydrophobic domain.;UniProt_AC=O06076;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	207107	207445	.	-	0	Locus=ML0145A;Name=ML0145A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0145A, len:338. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.004 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3121508	3122197	.	+	0	Locus=ML2615;Name=ML2615;Function=;Product=POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2615, len: 229 aa. Possible conserved membrane protein. Similar to several Mycobacterium tuberculosis hypothetical proteins e.g. Rv0200 TR:O53651 (EMBL:AL021928) fasta scores: E(): 0, 74.7% identity in 229 aa. Contains a possible N-terminal signal sequence and multiple possible membrane spanning hydrophobic domains.;UniProt_AC=O06077;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3155970	3156514	.	-	0	Locus=ML2638c;Name=ML2638c;Function=;Product=Possible quinone oxidoreductase (pseudogene);Comments=ML2638c, len: 545 bp. Possible pseudogene of M. tuberculosis orthologue Rv0149 (969 bp) (Best blastx scores: 121).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3140270	3141289	.	+	0	Locus=ML2627;Name=ML2627;Function=;Product=conserved hypothetical protein;Comments=ML2627, len: 339 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 35.8 kda protein Rv0216 OR MTCY08D5.11 TR:P96398 (EMBL:Z92669) fasta scores: E(): 0, 74.0% identity in 338 aa.;UniProt_AC=O06085;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3147704	3149053	.	-	0	Locus=ML2631c;Name=ML2631c;Function=;Product=possible oxidoreductase;Comments=ML2631c, len: 449 aa. Possible oxidoreductase. Similar to Mycobacterium tuberculosis hypothetical protein Rv0161 TR:O07406 (EMBL:Z97050) fasta scores: E(): 0, 78.8% identity in 449 aa, and to Escherichia coli glycolate oxidase subunit GlcD SW:GLCD_ECOLI (P52075) fasta scores: E(): 1.1e-29, 28.7% identity in 457 aa. Also similar to ML1103 from M. leprae. Contains Pfam match to entry PF01565 FAD_binding_4, FAD binding domain.;UniProt_AC=O06093;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3178893	3179180	.	-	0	Locus=ML2656c;Name=ML2656c;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML2656c, len: 288 bp. Possible pseudogene of M. tuberculosis orthologue Rv0128 (780 bp) (Best blastx scores: 242).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3179436	3179935	.	-	0	Locus=ML2657c;Name=ML2657c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML2657c, len: 500 bp. Possible pseudogene of M. tuberculosis orthologue Rv0127 (1368 bp) (Best blastx scores: 255).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3180268	3181913	.	-	0	Locus=ML2658c;Name=treS;Function=;Product=Trehalose synthase TreS (pseudogene);Comments=ML2658c, len: 1646 bp. Possible pseudogene of M. tuberculosis orthologue Rv0126|treS (1806 bp) (Best blastx scores: 589).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3184054	3185245	.	+	0	Locus=ML2660;Name=fusA2;Function=;Product=Probable elongation factor G FusA2 (pseudogene);Comments=ML2660, len: 1192 bp. Possible pseudogene of M. tuberculosis orthologue fusA2|Rv0120c (2145 bp) (Best blastx scores: 254).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3189384	3190316	.	-	0	Locus=ML2663c;Name=oxyS;Function=;Product=OXIDATIVE STRESS RESPONSE REGULATORY PROTEIN OXYS;Comments=ML2663c, len: 310 aa. oxyS, oxidative stress response regulatory protein. Similar to Mycobacterium tuberculosis OxyS|Rv0117 protein TR:O33175 (EMBL:AJ000188) fasta scores: E(): 0, 81.5% in 314 aa, and to Streptomyces coelicolor A3 OxyR a regulator of the hydroperoxide reductase system TR:Q9RN71 (EMBL:AF186371) fasta scores: E(): 5.9e-16, 31.2% in 292 aa. Contains a putative helix-turn-helix motif situated between residues 16..37 (+4.35 SD). Contains a probable helix-turn-helix motif at aa 16-37 (Score 1517, SD +4.35) Contains Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. Contains PS00044 Bacterial regulatory proteins.;UniProt_AC=Q9ZBE7;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	3234139	3234429	.	-	0	Locus=ML2685c;Name=rpsF;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S6 RPSF;Comments=ML2685c, len: 96 aa. Probable rpsF, 30S ribosomal protein S6. Similar to Bacillus subtilis 30s ribosomal protein S6 SW:RS6_BACSU (P21468) fasta scores: E(): 1.3e-10, 34.7% in 95 aa, and to Mycobacterium tuberculosis 30s ribosomal protein S6 Rv0053 SW:RS6_MYCTU (P71710) fasta scores: E(): 0, 91.7% in 96 aa. Contains Pfam match to entry PF01250 Ribosomal_S6, Ribosomal protein S6. Contains PS01048 Ribosomal protein S6 signature.;UniProt_AC=P46389;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	3149645	3150487	.	+	0	Locus=ML2632;Name=PE11;Function=;Product=PE-family protein (pseudogene);Comments=ML2632, len: 843 bp. Possible pseudogene of M. tuberculosis orthologue PE4|Rv0160c (1509 bp) and highly similar to PE3|Rv0159c (Best blastx scores: 165).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3246228	3246683	.	+	0	Locus=ML2695;Name=ML2695;Function=;Product=Probable ATP-binding protein ABC transporter (pseudogene);Comments=ML2695, len: 456 bp. Possible pseudogene similar to several M. tuberculosis ATP-binding transport proteins e.g. proV|Rv3758c and pstB|Rv0933 (Best blastx scores: 96).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1696463	1696780	.	+	0	Locus=ML1414;Name=PE_PGRS5;Function=;Product=PGRS-family protein (pseudogene);Comments=ML1414, len: 318 bp. Possible pseudogene similar to several M. tuberculosis PGRS-family proteins e.g. PE_PGRS15, PE_PGRS33, PE_PGRS23, PE_PGRS46 etc.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2659809	2660844	.	-	0	Locus=ML2241c;Name=PE_PGRS6;Function=;Product=PE_PGRS-family protein (pseudogene);Comments=ML2241c, len: 1036 bp. Possible pseudogene of M. tuberculosis orthologue PE_PGRS11|Rv0754 (1755 bp) (Best blastx scores: 185).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3240807	3241349	.	+	0	Locus=ML2691;Name=ML2691;Function=;Product=conserved hypothetical protein;Comments=ML2691, len: 180 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 20.4 kda protein Rv0047c cy21d4.10c precursor TR:P71704 (EMBL:Z80775) fasta scores: E(): 0, 89.4% in 180 aa, and to Streptomyces coelicolor hypothetical 25.2 kda protein TR:Q9X8T6 (EMBL:AL049826) fasta scores: E(): 4.2e-32, 51.9% in 181 aa. Contains a possible coiled-coil region between residues 120..140.;UniProt_AC=Q9CCY3;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2380922	2381473	.	+	0	Locus=ML1993;Name=fcoT;Function=;Product=conserved hypothetical protein;Comments=ML1993, len: 183 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetiacl protein Rv0098 SW:Y098_MYCTU (Q10894) (183 aa), Fasta scores: E(): 0, 65.6% identity in 180 aa overlap.;UniProt_AC=Q9CBG3;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3263121	3264176	.	-	0	Locus=ML2707c;Name=parA;Function=;Product=PROBABLE CHROMOSOME PARTITIONING PROTEIN PARA;Comments=ML2707c, len: 351 aa. Probable parA, chromosome partitioning protein. Similar to many proteins thought to be involved with chromosome partitioning e.g. Mycobacterium tuberculosis hypothetical 37.5 kda protein Rv3918c TR:O53596 (EMBL:AL021426) fasta scores: E(): 0, 78.1% in 347 aa, and to Bacillus subtilis soj protein SW:SOJ_BACSU (P37522) fasta scores: E(): 0, 52.6% in 251 aa. Contains Pfam match to entry PF00991 ParA, ParA family ATPase.;UniProt_AC=Q9CCX7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	262754	262939	.	-	0	Locus=ML0196c;Name=PE1;Function=;Product=PE family protein (pseudogene);Comments=ML0196c, len: 186 bp. Possible pseudogene of M. tuberculosis orthologue Rv3650|PE33 (285 bp) (Best blastx scores: 94);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	343372	343984	.	-	0	Locus=ML0263c;Name=PE2;Function=;Product=PE-family protein (pseudogene);Comments=ML0263c, len: 613 bp. Possible pseudogene of M. tuberculosis orthologue Rv1040c|PE8 (828 bp)  (Best blastx scores: 122);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3016111	3016419	.	-	0	Locus=ML2534c;Name=PE10;Function=;Product=PE-family protein;Comments=ML2534c, len: 102 aa. Member of the PE protein family. Similar to Mycobacterium tuberculosis PE-family protein Rv0285 PE5 MTV035.13 TR:O53690 (EMBL:AL021930) fasta scores: E(): 2.1e-23, 73.0% identity in 100 aa.;UniProt_AC=Q9CD31;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	3177822	3178823	.	+	0	Locus=ML2655;Name=fbpC2;Function=PROTEINS OF THE ANTIGEN 85 COMPLEX ARE RESPONSIBLE FOR THE HIGH AFFINITY OF MYCOBACTERIA TO FIBRONECTIN. POSSESSES A MYCOLYLTRANSFERASE ACTIVITY REQUIRED FOR THE BIOGENESIS OF TREHALOSE DIMYCOLATE (CORD FACTOR), A DOMINANT STRUCTURE NECESSARY FOR MAINTAINING CELL WALL INTEGRITY.;Product=SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C);Comments=ML2655, len: 333 aa. fbpC2, secreted antigen 85C, mycolyltransferase (EC 2.3.1.-). Previously sequenced and characterised: Mycobacterium leprae antigen 85-C precursor SW:A85C_MYCLE (Q05862) fasta scores: E(): 0, 100.0% in 333 aa. Similar to Rv0129c|P31953|A85C_MYCTU Antigen 85-C precursor (85C) from M. tuberculosis (340 aa), fasta scores: E(): 2.2e-119, (81.381% identity in 333 aa overlap). Also similar to ML0097 and ML2028 from M. leprae. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00756 Esterase, Putative esterase.;UniProt_AC=Q05862;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	3113033	3114727	.	-	0	Locus=ML2608c;Name=ilvD;Function=;Product=PROBABLE DIHYDROXY-ACID DEHYDRATASE ILVD (DAD);Comments=ML2608c, len: 564 aa. Probable ilvD, dihydroxy-acid dehydratase (EC 4.2.1.9). Similar to many Prokaryotic and Eukaryotic dihydroxy-acid dehydratases involved in valine and isoleucine biosynthesis e.g. Mycobacterium tuberculosis Rv0189c SW:ILVD_MYCTU (O07433) fasta scores: E(): 0, 90.0% identity in 560 aa, Saccharomyces cerevisiae dihydroxy-acid dehydratase, mitochondrial precursor ILV3 OR YJR016C OR J1450 SW:ILV3_YEAST (P39522) fasta scores: E(): 0, 48.5% identity in 555 aa. Contains Pfam match to entry PF00920 ILVD_EDD, Dehydratase family. Contains PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1.;UniProt_AC=O06069;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1800426	1801359	.	+	0	Locus=ML1493;Name=PE7;Function=;Product=PE-family protein (pseudogene);Comments=ML1493, len: 934 bp. Possible pseudogene of M. tuberculosis orthologue PE12|Rv1172c (927 bp) (Best blastx scores: 265).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1850794	1851060	.	-	0	Locus=ML1534c;Name=PE8;Function=;Product=PE family protein (pseudogene);Comments=ML1534c, len: 267 bp. Possible pseudogene of M. tuberculosis orthologue PE20|Rv1806 (300 bp) (Best blastx scores: 80).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2103811	2104015	.	-	0	Locus=ML1743c;Name=PE9;Function=;Product=PE-family protein (pseudogene);Comments=ML1743c, len: 205 bp. Possible pseudogene similar to M. tuberculosis PE-family protein (Best blastx scores: 79).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2572733	2573764	.	+	0	Locus=ML2163;Name=dapC;Function=;Product=Probable aminotransferase (pseudogene);Comments=ML2163, len: 1032 bp. Possible pseudogene of M. tuberculosis orthologue Rv0858c (1194 bp) (Best blastx scores: 361).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1305490	1305651	.	+	0	Locus=ML1125;Name=canA;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1125, len: 162 bp. Possible pseudogene of M. tuberculosis orthologue Rv1284 (492 bp) (Best blastx scores: 190).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1366635	1366998	.	+	0	Locus=ML1168;Name=mec;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1168, len: 364 bp. Possible pseudogene of M. tuberculosis orthologue Rv1334 (441 bp) (Best blastx scores: 127).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	75826	76357	.	-	0	Locus=ML0059B;Name=ML0059B;Function=;Product=hypothetical protein(pseudogene);Comments=ML0059B, len:531. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-26 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1582162	1583136	.	+	0	Locus=ML1330;Name=pafC;Function=;Product=Conserved hypothetical protein;Comments=ML1330, len: 324 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis Rv2095c SW:YK95_MYCTU (Q10704) (316 aa), Fasta scores: E(): 0, 74.2% identity in 322 aa overlap. also weakly similar to Bacillus subtilis putative transcriptional regulator TR:O34920 (EMBL:AF027868) (313 aa), Fasta scores: E(): 3.9e-05, 22.2% identity in 311 aa overlap. Contains a possible helix-turn-helix motif situated between residues 24..45 (+3.65 SD).;UniProt_AC=P54075;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2332636	2333622	.	+	0	Locus=ML1946;Name=glpX;Function=;Product=conserved hypothetical protein;Comments=ML1946, len: 328 aa. Conserved hypothetical protein. Similar to M. tuberculosis conserved hypothetical protein Rv1099c TR:O53447 (EMBL:AL021897) (328 aa), Fasta scores: E(): 0, 93.0% identity in 328 aa overlap, and to many others of the glpX family e.g. Escherichia coli GLPX protein SW:GLPX_ECOLI (P28860) (336 aa), Fasta scores: E(): 0, 41.7% identity in 321 aa overlap.;UniProt_AC=Q9CBH9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1903985	1904164	.	+	0	Locus=ML1578;Name=relB2;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1578, len: 180 bp. Possible pseudogene of M. tuberculosis orthologue Rv2865 (282 bp) (Best blastx scores: 104) and also similar to Rv1247c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1904195	1904454	.	+	0	Locus=ML1579;Name=relE2;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1579, len: 260 bp. Possible pseudogene of M. tuberculosis orthologue Rv2866 (264 bp) (Best blastx scores: 208).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	932052	933308	.	+	0	Locus=ML0789;Name=desA3;Function=;Product=Possible linoleoyl-CoA desaturase (pseudogene);Comments=ML0789, len: 1257 bp. Possible pseudogene of M. tuberculosis orthologue Rv3229c (Best blastx scores: 343).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	863379	863779	.	+	0	Locus=ML0720;Name=lrpA;Function=;Product=Probable transcriptional regulatory protein (probably AsnC family) (pseudogene);Comments=ML0720, len: 401 bp. Possible pseudogene of M. tuberculosis orthologue Rv3291c (453 bp) (Best blastx scores: 358).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	511131	511984	.	+	0	Locus=ML0413;Name=htdY;Function=;Product=Possible dehydrogenase (pseudogene);Comments=ML0413, len: 854 bp. Possible pseudogene of M. tuberculosis orthologue Rv3389c (873 bp) (Best blastx scores: 301);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	433561	434729	.	+	0	Locus=ML0343;Name=hsaA;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML0343, len: 1169 bp. Possible pseudogene of M. tuberculosis orthologue Rv3570c (1185 bp) (Best blastx scores: 413);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1581170	1582165	.	+	0	Locus=ML1329;Name=pafB;Function=;Product=conserved hypothetical protein;Comments=ML1329, len: 331 aa. Conserved hypothetical protein. Similar to several proteins of undefined function including: Rhodococcus erythropolis TR:P72264 (EMBL:Z82004) (330 aa), Fasta scores: E(): 0, 57.2% identity in 327 aa overlap and Mycobacterium tuberculosis Rv2096c SW:YK96_MYCTU (Q10705) (332 aa), Fasta scores: E(): 0, 80.2% identity in 329 aa overlap.;UniProt_AC=P54076;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	53719	54695	.	+	0	Locus=ML0043;Name=espB;Function=;Product=Conserved hypothetical ala-, gly-rich protein (pseudogene);Comments=ML0043, len: 977 bp. Possible pseudogene of M. tuberculosis orthologue Rv3881c (1380 bp) (Best blastx scores: 163);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	71142	72064	.	-	0	Locus=ML0057c;Name=espG1;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPG1 (PSEUDOGENE);Comments=ML0057c, len: 923 bp. Possible pseudogene of M. tuberculosis orthologue Rv3866 (849 bp) (Best blastx scores: 427);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	57567	57922	.	-	0	Locus=ML0046c;Name=espJ;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPJ(PSEUDOGENE);Comments=ML0046c, len: 356 bp. Possible pseudogene of M. tuberculosis orthologue Rv3878 (840 bp) (Best blastx scores: 118);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3013317	3014186	.	-	0	Locus=ML2530c;Name=espG3;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPG3;Comments=ML2530c, len: 289 aa. ESX-1 secretion-associated protein, similar to Mycobacterium tuberculosis ESX-1 secretion-associated protein Rv0289 (espG3) TR:O53694 (EMBL:AL021930) fasta scores: 75.9% identity in 295 aa. Contains a probable helix-turn-helix motif at aa 175-196.;UniProt_AC=Q9CD34;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	504794	505444	.	+	0	Locus=ML0407;Name=espD;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPD;Comments=ML0407, len: 216 aa. ESX-1 secretion-associated protein, highly similar to Rv3614c|O06269|AL123456 ESX-1 secretion-associated protein from M. tuberculosis (184 aa), Fasta scores: (71.5% identity in 186 aa overlap) and to Rv3867|O69732|AL123456 protein from M. tuberculosis (183 aa), Fasta scores: E(): 2.1e-28, (51.4% identity in 175 aa overlap). Previously sequenced as Q49730|U00015 (216 aa), Fasta scores: (100.0% identity in 216 aa overlap). Also similar to ML0056 from M. leprae.;UniProt_AC=Q49730;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	72683	73686	.	-	0	Locus=ML0058c;Name=espE;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPE(PSEUDOGENE);Comments=ML0058c, len: 1004 bp. Possible pseudogene of M. tuberculosis orthologue Rv3864 (1206 bp) (Best blastx scores: 110);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	55581	56699	.	+	0	Locus=ML0045;Name=espK;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPK. ALANINE AND PROLINE RICH PROTEIN(PSEUDOGENE);Comments=ML0045, len: 1119 bp. Possible pseudogene of M. tuberculosis orthologue Rv3879c (2187 bp) (Best blastx scores: 189);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	47271	48642	.	+	0	Locus=ML0039;Name=eccA2;Function=;Product=ESX CONSERVED COMPONENT ECCA2. PROBABLE CBXX/CFQX FAMILY PROTEIN(PSEUDOGENE);Comments=ML0039, len: 1372 bp. Possible pseudogene of M. tuberculosis orthologue Rv3884c (1857 bp) (Best blastx scores: 288);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	43199	43699	.	+	0	Locus=ML0036;Name=eccD2;Function=;Product=ESX CONSERVED COMPONENT ECCD2. PROBABLE TRANSMEMBRANE PROTEIN(PSEUDOGENE);Comments=ML0036, len: 501 bp. Possible pseudogene of M. tuberculosis orthologue Rv3887c (1527 bp) (Best blastx scores: 186);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	45397	46827	.	+	0	Locus=ML0038;Name=eccE2;Function=;Product=ESX CONSERVED COMPONENT ECCE2. POSSIBLE MEMBRANE PROTEIN(PSEUDOGENE);Comments=ML0038, len: 1431 bp. Possible pseudogene of M. tuberculosis orthologue Rv3885c (1611 bp) (Best blastx scores: 128);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	75225	75590	.	-	0	Locus=ML0059A;Name=ML0059A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0059A, len:365. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 9.00E-17 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1232042	1233172	.	-	0	Locus=ML1068c;Name=glgA;Function=;Product=Putative glycosyl transferase (pseudogene);Comments=ML1068c, len: 1131 bp. Possible pseudogene of M. tuberculosis orthologue Rv1212c (1164 bp) (Best blastx scores: 834).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3244470	3244622	.	+	0	Locus=ML2694A;Name=ML2694A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2694A, len:152. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4E-50 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3244717	3246162	.	+	0	Locus=ML2694B;Name=ML2694B;Function=;Product=glnQ; putative glutamine transport system permease protein / substrate-binding protein(pseudogene);Comments=ML2694B, len:1445. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-56 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1389492	1390165	.	-	0	Locus=ML1187E;Name=ML1187E;Function=;Product=hypothetical protein(pseudogene);Comments=ML1187E (ML1187C), len:406. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-28 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1393365	1393771	.	+	0	Locus=ML1189E;Name=ML1189E;Function=;Product=hypothetical protein(pseudogene);Comments=ML1189E (ML1189C), len:406. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-28 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1378330	1378828	.	+	0	Locus=ML1179A;Name=ML1179A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1179A, len:498. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-16 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1378899	1379314	.	+	0	Locus=ML1179B;Name=ML1179B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1179B, len:415. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-24 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1379419	1380228	.	+	0	Locus=ML1179C;Name=ML1179C;Function=;Product=hypothetical protein(pseudogene);Comments=ML1179C, len:809. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-15 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1383009	1383345	.	+	0	Locus=ML1183A;Name=ML1183A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1183A, len:336. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1384768	1385145	.	-	0	Locus=ML1184A;Name=ML1184A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1184A, len:377. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-23 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1385173	1385718	.	-	0	Locus=ML1185A;Name=ML1185A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1185A, len:545. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-20 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1388186	1388599	.	+	0	Locus=ML1187A;Name=ML1187A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1187A, len:413. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-15 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1388579	1389379	.	+	0	Locus=ML1187B;Name=ML1187B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1187B, len:800. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-23 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	163770	164039	.	-	0	Locus=ML0121c;Name=ML0121c;Function=;Product=Conserved hypothetical protein;Comments=ML0121c, len: 89 aa. Conserved hypothetical protein. Shares region of weak similarity with Q9X7X8|AL049485 hypothetical protein SC6A5.32C from Streptomyces coelicolor (155 aa), Fasta scores: E(): 0.0056, (43.1% identity in 58 aa overlap).;UniProt_AC=Q9CD93;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	169585	170406	.	+	0	Locus=ML0126;Name=ML0126;Function=;Product=Hypothetical protein;Comments=ML0126, len: 273 aa. Hypothetical unknown protein.;UniProt_AC=Q9CD90;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	202307	202561	.	-	0	Locus=ML0141c;Name=ML0141c;Function=;Product=Hypothetical protein;Comments=ML0141c, len: 84 aa. Improbable CDS suggested by GC frameplot. Possibly the remains of a disrupted gene.;UniProt_AC=Q9CD77;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1747951	1748595	.	-	0	Locus=ML1454c;Name=nadD;Function=;Product=PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE) (NAMN ADENYLYLTRANSFERASE);Comments=ML1454c, len: 214 aa. Probable nadD, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18). Similar to several e.g. Mycobacterium tuberculosis Rv2421c TR:O86328 (EMBL:Z81368) (211 aa), Fasta scores: E(): 0, 80.2% identity in 212 aa overlap.;UniProt_AC=Q9CBZ8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	993885	994268	.	+	0	Locus=ML0837;Name=ML0837;Function=;Product=conserved hypothetical protein;Comments=ML0837, len: 127 aa. Conserved hypothetical protein, similar in part to several aldolases e.g. SCI8.29C|Q9RJ24|AL132644 putative aldolase from Streptomyces coelicolor (240 aa) fasta scores: E(): 0.001, 32.5% identity in 120 aa.;UniProt_AC=Q9CCG0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1131301	1131765	.	+	0	Locus=ML0963;Name=ML0963;Function=;Product=hypothetical protein;Comments=ML0963, len: 154 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCC4;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1172602	1172877	.	-	0	Locus=ML1001c;Name=ML1001c;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML1001c, len: 91 aa. Conserved hypothetical protein, similar to Mycobacterium tuberculosis Rv2722 TR:O33227 (EMBL:Z98209) (82 aa), Fasta scores: E(): 4.4e-05, 37.5% identity in 88 aa overlap.;UniProt_AC=Q9CCB9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2487716	2487901	.	+	0	Locus=ML2091;Name=ML2091;Function=;Product=hypothetical protein;Comments=ML2091, len: 61 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBE6;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2589798	2590049	.	-	0	Locus=ML2178c;Name=ML2178c;Function=;Product=hypothetical protein;Comments=ML2178c, len: 83 aa. Hypothetical unknown protein. Similar in part to Q8VJM5 Hypothetical protein MT2367 from M. tuberculosis CDC1551 (110 aa), fasta scores: E(): 0.093, (48.387% identity in 31 aa overlap).;UniProt_AC=Q9CBD0;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1803625	1805478	.	-	0	Locus=ML1497c;Name=lpqW;Function=;Product=PROBABLE CONSERVED LIPOPROTEIN LPQW;Comments=ML1497c, len: 617 aa. Probable lpqW, conserved lipoprotein. Similar to Mycobacterium tuberculosis Rv1166 TR:O50422 (EMBL:AL01018) (635 aa), Fasta scores: E(): 0, 80.4% identity in 632 aa overlap. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CBX3;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1623030	1623983	.	+	0	Locus=ML1362;Name=ML1362;Function=;Product=possible conserved secreted protein;Comments=ML1362, len: 317 aa. Possible conserved secreted protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1698. Contains a possible N-terminal signal sequence.;UniProt_AC=Q49894;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2688069	2688290	.	-	0	Locus=ML2265c;Name=ML2265c;Function=;Product=hypothetical protein;Comments=ML2265c, len: 73 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBB3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	2331783	2332556	.	-	0	Locus=ML1945c;Name=ML1945c;Function=;Product=conserved hypothetical protein;Comments=ML1945c, len: 257 aa. Conserved hypothetical protein. Similar to M. tuberculosis conserved hypothetical protein Rv1100 TR:O53448 (EMBL:AL021897) (233 aa), Fasta scores: E(): 0, 63.8% identity in 257 aa overlap.;UniProt_AC=Q9X787;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2361226	2361573	.	-	0	Locus=ML1976c;Name=ML1976c;Function=;Product=hypothetical protein;Comments=ML1976c, len: 115 aa. Hypothetical unknown protein (questionable CDS).;UniProt_AC=Q9CBH4;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1390177	1390563	.	-	0	Locus=ML1187D;Name=ML1187D;Function=;Product=hypothetical protein(pseudogene);Comments=ML1187D, len:386. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-35 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1391254	1392402	.	+	0	Locus=ML1188A;Name=ML1188A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1188A, len:1148. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-58 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2661051	2661782	.	-	0	Locus=ML2242c;Name=ML2242c;Function=;Product=conserved hypothetical protein;Comments=ML2242c, len: 243 aa. Conserved hypothetical protein, similar to Q52145|M23557 Mycobacterium fortuitum plasmid pAL5000 hypothetical 26.6 kda protein (255 aa), fasta scores: E(): 9.9e-05, (27.2% identity in 250 aa).;UniProt_AC=Q50153;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3250676	3253069	.	+	0	Locus=ML2699;Name=ML2699;Function=;Product=putative secreted protein.;Comments=ML2699, len: 797 aa. Putative secreted protein. Similar to Mycobacterium tuberculosis hypothetical 83.9 kda protein TR:O05436 (EMBL:Z94121) fasta scores: E(): 0, 72.4% in 803 aa. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CCY0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3222411	3225413	.	+	0	Locus=ML2678;Name=ML2678;Function=;Product=LONG CONSERVED HYPOTHETICAL PROTEIN;Comments=ML2678, len: 1000 aa. Long conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 124.5 kda protein Rv2566 cy9c4.02c TR:Q50732 (EMBL:Z77250) fasta scores: E(): 0, 50.3% in 1128 aa.;UniProt_AC=O53120;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1392879	1393013	.	-	0	Locus=ML1189A;Name=ML1189A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1189A, len:134. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1393254	1393349	.	+	0	Locus=ML1189B;Name=ML1189B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1189B, len:95. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-08 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1393820	1395115	.	+	0	Locus=ML1189D;Name=ML1189D;Function=;Product=hypothetical protein(pseudogene);Comments=ML1189D, len:1295. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-64 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1396216	1396335	.	-	0	Locus=ML1190A;Name=ML1190A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1190A, len:119. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 9.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1429774	1430242	.	-	0	Locus=ML1209A;Name=ML1209A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1209A, len:468. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-12 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1431406	1431580	.	-	0	Locus=ML1210A;Name=ML1210A;Function=;Product=glgZ; maltooligosyl trehalose trehalohydrolase(pseudogene);Comments=ML1210A, len:174. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-07 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1108030	1108169	.	-	0	Locus=ML0937c;Name=ML0937c;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML0937c, len: 140 bp. Possible transposase remnant, some similarity to Q9RBZ3 transposase from Pseudomonas syringae (357 aa), (blastx scores: 51) and to Q44454|Z18270 transposase from Agrobacterium tumefaciens (366 aa), (blastx scores: 45). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1499659	1499766	.	+	0	Locus=ML1254A;Name=ML1254A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1254A, len:107. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-13 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1518858	1519217	.	+	0	Locus=ML1275A;Name=ML1275A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1275A, len:359. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-31 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2927718	2928005	.	-	0	Locus=ML2453c;Name=ML2453c;Function=;Product=POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2453c, len: 95 aa. Possible conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical Rv0476 precursor MTCY20g9.02 SW:Y476_MYCTU (Q11143) fasta scores: E(): 1.6e-24, 83.9% identity in 87 aa. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CB43;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	7318	11067	.	+	0	Locus=ML0006;Name=gyrA;Function=DNA Gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. This DNA Gyrase is made up of two chains. The A chain is responsible for DNA breakage and rejoining and the B chain catalyzes ATP hydrolysis [Catalytic activity: ATP-dependent breakage, passage and rejoining of double-stranded DNA].;Product=Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase);Comments=ML0006, len: 1249 aa. Probable gyrA, DNA gyrase subunit A (EC 5.99.1.3) (see citations below), highly similar to other Mycobacterial DNA GYRASES SUBUNIT A e.g. Rv0006|GYRA_MYCTU|Q07702 from M. tuberculosis (838 aa), Fasta scores: E(): 0, (91.1% identity in 695 aa overlap) and to GYRA_MYCSM|P48354 from Mycobacterium smegmatis (842 aa), Fasta scores: E(): 0, (88.2% identity in 692 aa overlap). Previously sequenced as GYRA_MYCLE|Q57532 (1273 aa), Fasta scores: E(): 0, (99.9% identity in 1246 aa overlap). Contains a probable intein from aa 131 to 550 inclusive. Contains 2 Pfam matches to entry PF00521 DNA_topoisoIV, DNA gyrase/topoisomerase IV, subunit A. Contains PS00018 EF-hand calcium-binding domain. Contains PS00881 Protein splicing signature.;UniProt_AC=Q57532;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	15993	16541	.	+	0	Locus=ML0011;Name=ppiA;Function=;Product=Probable peptidyl-prolyl cis-trans isomerase PpiA (PPIase A) (Rotamase A);Comments=ML0011, len: 182 aa. Probable ppiA, peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8)(see citations below), similar to Rv0009|CYPA_MYCTU|P71578 ppiA from M. tuberculosis (182 aa), Fasta scores: E(): 0, (90.1% identity in 182 aa overlap) and P77949|U64692 ScCypB peptidyl-prolyl cis-trans isomerase B from  Streptomyces chrysomallus (175 aa), Fasta scores: E(): 0, (63.3% identity in 166 aa overlap). Also similar to ML0492 from M. leprae. Contains Pfam match to entry PF00160 pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase. Belongs to the cyclophilin-type PPIase family.;UniProt_AC=Q9CDE9;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	212897	213010	.	-	0	Locus=ML0150A;Name=ML0150A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0150A, len:113. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-07 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	18325	19023	.	+	0	Locus=ML0015;Name=trpG;Function=Possibly involved in biosynthesis of tryptophan (at the first step).  Thought to be a tetramer of two components I and two components II: component I (ML1269/trpE) catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II (ML0015/trpG) provides glutamine aminotranferase activity. Possibly participates in the tryptophan-dependent indole-3-acetic acid production [Catalytic activity: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate]. ;Product=Possible anthranilate synthase component II TrpG (glutamine amidotransferase);Comments=ML0015, len: 232 aa. Possible trpG, anthranilate synthase component II (glutamine amidotransferase) (EC 4.1.3.27), equivalent to Rv0013|Q50183|Z70722 possible trpG, anthranilate synthase component II from M. tuberculosis (232 aa), Fasta scores: E(): 0, (100.0% identity in 232 aa overlap); and similar to others e.g. TRPG_AZOBR|P26922 trpG from Azospirillum brasilense (196 aa), Fasta scores: E(): 0, (56.1% identity in 187 aa overlap). Previously sequenced as Q50183. Contains Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I. Contains PS00442 Glutamine amidotransferases class-I active site. Similarity to other type-1 glutamine aminotransferase domains. Note that previously known as pabA.;UniProt_AC=Q50183;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	34033	34638	.	-	0	Locus=ML0029c;Name=ML0029c;Function=;Product=Possible transmembrane protein;Comments=ML0029c, len: 201 aa. Possible transmembrane protein. Contains a region similar to part of several bacterial hypothetical membrane proteins e.g. Q9ZBW2|AL034443 putative transmembrane protein SC4B5.06 from Streptomyces coelicolor (345 aa), Fasta scores: E(): 2.4e-14, (54.1% identity in 109 aa overlap). The coding frame predicted by GC frameplot changes to either side of this region of similarity, suggesting that an ancestral CDS was disrupted. Given this, ML0029 may not be functional. Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDE0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	34750	35091	.	-	0	Locus=ML0030c;Name=ML0030c;Function=;Product=Possible conserved transmembrane protein;Comments=ML0030c, len: 113 aa. Possible conserved transmembrane protein, highly similar to Rv0039c|P71696|AL123456 possible conserved transmembrane protein from M. tuberculosis (115 aa), Fasta scores: E(): 2.2e-25, (63.2% identity in 114 aa overlap). Previously sequenced as O32871|Z70722 (113 aa), Fasta scores: E(): 0, (100.0% identity in 113 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=O32871;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	88741	89106	.	-	0	Locus=ML0067c;Name=hns;Function=;Product=Possible histone-like protein Hns;Comments=ML0067c, len: 121 aa. Possible hns, histone-like protein, similar to Rv3852|P96225|AL123456 hns, HU-histone protein from M. tuberculosis (134 aa), Fasta scores: E(): 6.1e-12, (51.5% identity in 134 aa overlap). Contains PAKKX repeats similar to those in histone H1 proteins.;UniProt_AC=Q9CDD1;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	91913	92446	.	-	0	Locus=ML0071c;Name=ML0071c;Function=;Product=Conserved hypothetical protein;Comments=ML0071c, len: 177 aa. Conserved hypothetical protein, equivalent to Rv3847|P96230|AL123456) hypothetical protein from M. tuberculosis (177 aa), Fasta scores: E(): 0, (96.6% identity in 177 aa overlap); and Q9F9R0 HYPOTHETICAL 18.5 KDA PROTEIN from Mycobacterium paratuberculosis (177 aa).;UniProt_AC=Q9CDC7;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	94092	95126	.	+	0	Locus=ML0073;Name=ML0073;Function=;Product=Probable conserved transmembrane protein;Comments=ML0073, len: 344 aa. Probable conserved transmembrane protein, highly similar to Rv3843c|P96235|Z83864 transmembrane protein from M. tuberculosis (342 aa), Fasta scores: E(): 0, (63.0% identity in 349 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDC6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	239809	239958	.	-	0	Locus=ML0172A;Name=ML0172A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0172A, len:149. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-12 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	99390	100085	.	+	0	Locus=ML0079;Name=ML0079;Function=;Product=Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase);Comments=ML0079, len: 231 aa. Probable phosphoglycerate mutase (EC 5.4.2.-), highly similar to Rv3837c|P96241|AL123456 probable phosphoglycerate mutase from M. tuberculosis (232 aa), Fasta scores: E(): 0, (71.6% identity in 232 aa overlap). Similar to Q9ZAX0|U73808 pgm, 2,3-PDG dependent phosphoglycerate mutase from Amycolatopsis methanolica (205 aa), Fasta scores: E(): 9.3e-24, (39.7% identity in 204 aa overlap). Also similar to ML1452 from M. leprae. Contains Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase family. Contains PS00175 Phosphoglycerate mutase family phosphohistidine signature.;UniProt_AC=Q9CDC3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	110329	111174	.	+	0	Locus=ML0089;Name=ML0089;Function=;Product=Conserved hypothetical protein;Comments=ML0089, len: 281 aa. Conserved hypothetical protein, highly similar to Rv3813c|O07810|AL123456 conserved hypothetical protein from M. tuberculosis (273 aa), Fasta scores: E(): 0, (80.4% identity in 271 aa overlap). Similar to many other bacterial hypothetical proteins. Contains Pfam match to entry PF00592 DUF3, Cof family.;UniProt_AC=Q9CDB9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	114130	115371	.	+	0	Locus=ML0092;Name=glf;Function=;Product=Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme);Comments=ML0092, len: 413 aa. Probable glf (alternate gene name: ceoA), UDP-galactopyranose mutase (EC 5.4.99.9) (see citations below), highly similar to Rv3809c|O06934|U96128 glf, UDP-galactopyranose mutase from M. tuberculosis (399 aa), Fasta scores: E(): 0, (86.6% identity in 396 aa overlap). Also similar to others e.g. GLF_ECOLI|P37747 glf, UDP-galactopyranose mutase from Escherichia coli (367 aa), Fasta scores: E(): 0, (43.1% identity in 378 aa overlap).;UniProt_AC=Q9CDB8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	118819	120768	.	+	0	Locus=ML0096;Name=ML0096;Function=;Product=Probable conserved transmembrane protein;Comments=ML0096, len: 649 aa. Probable conserved transmembrane protein, highly similar to Rv3805c|O53582|AL123456 probable transmembrane protein from M. tuberculosis (627 aa), Fasta scores: E(): 0, (80.9% identity in 629 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDB4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	126518	131872	.	+	0	Locus=ML0101;Name=pks13;Function=;Product=Polyketide synthase Pks13;Comments=ML0101, len: 1784 aa. Probable pks13, polyketide synthase (EC undetermined), similar to many polyketide synthases from M. tuberculosis e.g. Rv3800c|O53579 pks13, polyketide synthase (1733 aa), Fasta scores: E(): 0, (83.6% identity in 1748 aa overlap); and PPSA_MYCTU|Q10977 ppsA, phenolpthiocerol synthesis polyketide synthase (1876 aa), Fasta scores: E(): 0, (36.1% identity in 1277 aa overlap). Similar to many others e.g. AAF71766|AF263912 nystatin biosynthesis polyketide synthase from Streptomyces noursei nysI (9477 aa), Fasta scores: E(): 0, (33.4% identity in 1215 aa overlap). Also similar to ML0135, ML0139, ML1229, ML2353, ML2354, ML2355, ML2356, and ML2357 from M. leprae. Similar to ML2607c a possible pseudogene similar to M. tuberculosis pks13. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00975 Thioesterase, Thioesterase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q9CDB1;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	139821	143156	.	-	0	Locus=ML0105c;Name=embA;Function=Involved in the biosynthesis of the mycobacterial cell wall arabinan and resistance to ethambutol (Emb; dextro-2,2'-(ethylenediimino)-di-1-butanol). Polymerizes arabinose into the arabinan of arabiogalactan [Catalytic activity: UDP-L-arabinose + indol-3-ylacetyl-myo-inositol = UDP + indol-3-ylacetyl-myo-inositol L-arabinoside].;Product=Probable integral membrane indolylacetylinositol arabinosyltransferase EmbA (arabinosylindolylacetylinositol synthase);Comments=ML0105c, len: 1111 aa. Probable embA, integral membrane protein, indolylacetylinositol arabinosyltransferase (EC 2.4.2.34) (see citations below), similar to Rv3794|Q50394|AL123456 embA, indolylacetylinositol arabinosyltransferase from M. tuberculosis (1094 aa), Fasta scores: E(): 0, (64.2% identity in 1108 aa overlap); and to other putative mycobacterial arabinosyltransferases. Also similar to ML0104 and ML0106 from M. leprae. Involved in resistance to ethambutol in M. tuberculosis. In M. tuberculosis embA is thought to be regulated by embR, but this regulator doesn't exist in M. leprae. Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDA8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	144115	147327	.	-	0	Locus=ML0106c;Name=embC;Function=Involved in the biosynthesis of the mycobacterial cell wall arabinan and resistance to ethambutol (Emb; dextro-2,2'-(ethylenediimino)-di-1-butanol). Polymerizes arabinose into the arabinan of arabiogalactan [Catalytic activity: UDP-L-arabinose + indol-3-ylacetyl-myo-inositol = UDP + indol-3-ylacetyl-myo-inositol L-arabinoside].;Product=Probable integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase);Comments=ML0106c, len: 1070 aa. Probable embC, integral membrane protein, indolylacetylinositol arabinosyltransferase (EC 2.4.2.34) (see citations below), highly similar to Rv3793|P72059|AL123456 embC, indolylacetylinositol arabinosyltransferase from M. tuberculosis (1094 aa), Fasta scores: E(): 0, (82.8% identity in 1075 aa overlap); and to other putative mycobacterial arabinosyltransferases. Also similar to ML0104 and ML0105 from M. leprae. Involved in resistance to ethambutol in M. tuberculosis. Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDA7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	155413	155961	.	-	0	Locus=ML0115c;Name=ML0115c;Function=;Product=Conserved hypothetical protein;Comments=ML0115c, len: 182 aa. Conserved hypothetical protein, highly similar to Rv3780|Y1I0_MYCTU|P72046 conserved hypothetical protein from M. tuberculosis (178 aa), Fasta scores: E(): 0, (82.9% identity in 170 aa overlap); and to Q9XA56|AL096822 hypothetical protein SCGD3.23C from Streptomyces coelicolor (179 aa), Fasta scores: E(): 0, (65.7% identity in 178 aa overlap). Note start changed since original submission.;UniProt_AC=Q9CD99;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	151578	151949	.	-	0	Locus=ML0110c;Name=ML0110c;Function=;Product=Probable conserved transmembrane protein;Comments=ML0110c, len: 123 aa. Probable conserved transmembrane protein, highly similar to Rv3789|Y1I9_MYCTU|P72055 hypothetical protein from M. tuberculosis (121 aa), Fasta scores: E(): 0, (73.0% identity in 122 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDA3;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	153663	154514	.	-	0	Locus=ML0113c;Name=ML0113c;Function=;Product=Possible L-rhamnosyltransferase;Comments=ML0113c, len: 283 aa. Possible L-rhamnosyltransferase (EC 2.4.1.-), highly similar to Rv3782|P72048 possible L-rhamnosyltransferase from M. tuberculosis (304 aa), FASTA scores: opt: 1583, E(): 9.3e-96, (81.6% identity in 277 aa overlap). Similar to Q8NTV4 predicted glycosyltransferases from Corynebacterium glutamicum ATCC (313 aa), FASTA scores: opt: 1170, E(): 4.4e-73, (63.1% identity in 279 aa overlap); and other putative transferases. Note that previously known as rfbE.;UniProt_AC=Q9CDA1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	160495	161730	.	-	0	Locus=ML0119c;Name=lipE;Function=;Product=Probable lipase LipE;Comments=ML0119c, len: 411 aa. Probable lipE, hydrolase lipase (EC 3.1.-.-), highly similar to Rv3775|P72041|AL123456 probable lipE, lipase from M. tuberculosis (415 aa), Fasta scores: E(): 0, (84.7% identity in 406 aa overlap) . Similar to bacterial esterases e.g. O87861|Z15137 estA, esterase A from Streptomyces chrysomallus (389 aa), Fasta scores: E(): 2.6e-18, (29.9% identity in 348 aa overlap).;UniProt_AC=Q9CD95;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	222650	223942	.	+	0	Locus=ML0159;Name=ML0159;Function=;Product=Probable conserved integral membrane protein;Comments=ML0159, len: 430 aa. Probable conserved integral membrane protein, highly similar to Rv0955|Y955_MYCTU|P71555 integral membrane protein from M. tuberculosis (455 aa), Fasta scores: E(): 0, (75.9% identity in 419 aa overlap). Previously sequenced as Q9Z5H7|AL035500 (430 aa), Fasta scores: E(): 0, (99.8% identity in 430 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9Z5H7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	218458	219639	.	+	0	Locus=ML0155;Name=sucC;Function=;Product=Probable succinyl-CoA synthase, (beta chain) SucC (SCS-beta);Comments=ML0155, len: 393 aa. Probable sucC, succinyl-CoA synthetase, beta chain (EC 6.2.1.5), highly similar to Rv0951|SUCC_MYCTU|P71559 sucC, succinyl-CoA synthetase beta chain from M. tuberculosis (387 aa), Fasta scores: E(): 0, (86.7% identity in 391 aa overlap). Similar to many e.g. SUCC_THEFL|P25126 sucC, succinyl-CoA synthase beta chain from Thermus aquaticus  (378 aa), Fasta scores: E(): 0, (48.7% identity in 384 aa overlap). Previously sequenced as Q9Z5H8 |AL035500 (393 aa), Fasta scores: E(): 0, (100.0% identity in 393 aa overlap). Contains Pfam match to entry PF00549 ligase-CoA, CoA-ligases. Contains Pfam match to entry PF02222 ATP-grasp, ATP-grasp domain. Contains PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3.;UniProt_AC=Q9Z5H8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	241217	242776	.	+	0	Locus=ML0175;Name=mprB;Function=;Product=Probable two component sensor kinase MprB;Comments=ML0175, len: 519 aa. Probable mprB, two component sensor kinase, transmembrane protein (EC 2.7.3.-) (see citation below), highly similar to Rv0982|O53895|AL123456 mprB, two component sensor kinase from M. tuberculosis (504 aa), Fasta scores: E(): 0, (81.0% identity in 521 aa overlap); and similar to many others e.g. COPS_PSESM|Q02541 copS, sensor protein involved in activation of copper resistance from Pseudomonas syringae (487 aa), Fasta scores: E(): 1.2e-18, (27.9% identity in 427 aa overlap). Also similar to ML0774, ML2124 and ML2440 from M. leprae. Previously sequenced as Q9Z5G7|AL035500) (519 aa), Fasta scores: E(): 0, (100.0% identity in 519 aa overlap).  Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF00672 DUF5, Domain found in bacterial signal proteins. Contains Pfam match to entry PF00512 signal, Histidine kinase. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9Z5G7;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	246049	246348	.	-	0	Locus=ML0180c;Name=ML0180c;Function=;Product=Conserved hypothetical Serine rich protein;Comments=ML0180c, len: 99 aa. Conserved hypothetical ser-rich protein (especially in C-terminus), highly similar to Rv0991c|O05574|AL123456 hypothetical protein with Ser-rich C-terminus from M. tuberculosis (110 aa), Fasta scores: E(): 1.1e-23, (78.5% identity in 93 aa overlap). Similar to other bacterial Ser-rich hypothetical proteins e.g. CAB90971|AL355832 hypothetical protein SCE22.04 from Streptomyces coelicolor (110 aa), Fasta scores: E(): 2.6e-15, (54.5% identity in 99 aa overlap). Previously sequenced as Q9Z5G3|AL035500 (120 aa), Fasta scores: E(): 1.1e-32, (100.0% identity in 99 aa overlap).;UniProt_AC=Q9CD66;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	410355	410852	.	+	0	Locus=ML0320;Name=ML0320;Function=;Product=Possible transcription factor;Comments=ML0320, len: 165 aa. Possible transcriptional factor, highly similar to Rv3583c|O53568|AL123456 possible transcription factor from M. tuberculosis (162 aa), Fasta scores: E(): 0, (97.5% identity in 162 aa overlap). Similar to many putative bacterial transcription factors e.g. Q9L0Q9|SCD8A.05 putative transcriptional factor regulator from Streptomyces coelicolor A3(2) (160 aa), and weak similarity to Q50887|Z56280 carD, transcription factor from Myxococcus xanthus (316 aa), Fasta scores: E(): 9.1e-13, (31.2% identity in 154 aa overlap).;UniProt_AC=Q9CCW7;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	246423	247016	.	-	0	Locus=ML0181c;Name=ML0181c;Function=;Product=Conserved hypothetical protein;Comments=ML0181c, len: 197 aa. Conserved hypothetical protein, highly similar to Rv0992c|O05575|AL123456 conserved hypothetical protein from M. tuberculosis (197 aa), Fasta scores: E(): 0, (72.6% identity in 197 aa overlap). Similar to many hypothetical proteins and shows weak similarity to methenyltetrahydrofolate synthetases e.g. Q8NS05 5-formyltetrahydrofolate cyclo-ligase from Corynebacterium glutamicum (190 aa), Fasta scores: E(): 3.3e-15, (35.1% identity in 188 aa overlap). Previously sequenced as Q9Z5G2|AL035500 (197 aa), Fasta scores: E(): 0, (100.0% identity in 197 aa overlap). Contains Pfam match to entry PF01812 5-FTHF_cyc-lig, 5-formyltetrahydrofolate cyclo-ligase.;UniProt_AC=Q9Z5G2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	258646	259491	.	+	0	Locus=ML0193;Name=ML0193;Function=;Product=Conserved hypothetical protein;Comments=ML0193, len: 281 aa. Conserved hypothetical protein, highly similar to Rv1003|YA03_MYCTU|O05588 conserved hypothetical protein from M. tuberculosis (285 aa), Fasta scores: E(): 0, (74.0% identity in 277 aa overlap). Similar to many bacterial hypothetical proteins e.g. Q9RKD4|AL132674 conserved hypothetical protein SCE87.04C from Streptomyces coelicolor (286 aa), Fasta scores: E(): 0, (50.5% identity in 277 aa overlap). Contains Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases.;UniProt_AC=Q9CD60;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	249407	250051	.	+	0	Locus=ML0184;Name=rimJ;Function=;Product=Possible ribosomal-protein-alanine acetyltransferase RimJ (acetylating enzyme for N-terminal of ribosomal protein S5);Comments=ML0184, len: 214 aa. Possible rimJ, ribosomal-protein-alanine acetyltransferase (EC 2.3.1.128), highly similar to Rv0995|O05578|AL123456 rimJ, ribosomal-protein-alanine acetyltransferase from M. tuberculosis (203 aa), Fasta scores: E(): 0, (86.0% identity in 200 aa overlap). Similar to RIMJ_ECOLI|P09454 rimJ, ribosomal-protein-alanine acetyltransferase from Escherichia coli (194 aa), Fasta scores: E(): 9.4e-12, (28.0% identity in 189 aa overlap); and to many other acetyltransferases. Previously sequenced as Q9Z5F9|AL035500 (218 aa), Fasta scores: E(): 0, (100.0% identity in 214 aa overlap). Contains Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family. Seems to belong to the acetyltransferase family, rimJ subfamily.;UniProt_AC=Q9CD65;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	276707	277777	.	-	0	Locus=ML0205c;Name=ML0205c;Function=;Product=Probable conserved integral membrane protein;Comments=ML0205c, len: 356 aa. Probable conserved integral membrane protein, highly similar to Rv3629c|O06378|AL123456 conserved integral membrane protein from M. tuberculosis (365 aa), Fasta scores: E(): 0, (66.2% identity in 361 aa overlap). Similar to other bacterial hypothetical membrane proteins e.g. CAB92842|AL356892 putative integral membrane protein SCC8A.24C from Streptomyces coelicolor (380 aa), Fasta scores: E(): 1e-21, (47.5% identity in 377 aa overlap). Previously sequenced as O69543|AL023093 (356 aa), Fasta scores: E(): 0, (100.0% identity in 356 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=O69543;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	547313	547789	.	+	0	Locus=ML0447;Name=ML0447;Function=;Product=Conserved hypothetical protein;Comments=ML0447, len: 158 aa. Conserved hypothetical protein. Similar to region of cytochrome P450s e.g. CPXB_BACME|P14779|CYP102A1 cytochrome P450(BM-3) from Bacillus megaterium (1048 aa), Fasta scores: E(): 0.00033, (31.8% identity in 132 aa overlap). Previously sequenced as O07142|Z96801 (126 aa), Fasta scores: E(): 0, (99.2% identity in 126 aa overlap).;UniProt_AC=Q9CCU2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	279051	279770	.	+	0	Locus=ML0207;Name=ML0207;Function=;Product=Possible transferase (possibly glycosyltransferase);Comments=ML0207, len: 239 aa. Possible transferase (EC 2.-.-.-), more specifically a glycosyltransferase (EC 2.4.-.-), highly similar to Rv3631|O06376|AL123456 possible glycosyltransferase from M. tuberculosis (241 aa), Fasta scores: E(): 0, (80.8% identity in 239 aa overlap). Similar to many bacterial hypothetical proteins and dolichyl-phosphate mannose synthases. Previously sequenced as O69542|PS50167 (239 aa), Fasta scores: E(): 0, (99.6% identity in 239 aa overlap). Also similar to ML1440 from M. leprae. Contains Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferases.;UniProt_AC=O69542;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	284580	285551	.	+	0	Locus=ML0213;Name=mesJ;Function=;Product=Possible cell cycle protein MesJ;Comments=ML0213, len: 323 aa. Possible mesJ, cell cycle protein, highly similar to Rv3625c|Y0C5_MYCTU|O06382 possible mesJ, cell cycle protein from M. tuberculosis (323 aa), Fasta scores: E(): 0, (78.0% identity in 327 aa overlap). Similar to many others e.g. MESJ_ECOLI|P52097 mesJ, putative cell cycle protein from Escherichia coli (432 aa), Fasta scores: E(): 3.9e-12, (33.0% identity in 279 aa overlap). Previously sequenced as Y0C5_MYCLE|O69538 (323 aa), Fasta scores: E(): 0, (100.0% identity in 323 aa overlap). Belongs to the UPF0072 (mesJ/ycf62) family.;UniProt_AC=O69538;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	297543	297941	.	+	0	Locus=ML0225;Name=folB;Function=Involved in folate biosynthesis. Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin [Catalytic activity: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde].;Product=Probable dihydroneopterin aldolase FolB (DHNA);Comments=ML0225, len: 132 aa. Probable folB, dihydroneopterin aldolase (EC 4.1.2.25), highly similar to Rv3607c|FOLB_MYCTU|O06275 probable folB, dihydroneopterin aldolase from M. tuberculosis (133 aa), Fasta scores: E(): 0, (74.8% identity in 131 aa overlap). Similar to many others e.g. FOLB_STAAU|P56740 folB, dihydroneopterin aldolase from Staphylococcus aureus (121 aa), Fasta scores: E(): 1.9e-09, (33.9% identity in 121 aa overlap). Previously sequenced as FOLB_MYCLE|O69529 (132 aa), Fasta scores: E(): 0, (100.0% identity in 132 aa overlap). Contains Pfam match to entry PF02152 FolB, Dihydroneopterin aldolase. Belongs to the DHNA family.;UniProt_AC=O69529;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	302404	302832	.	+	0	Locus=ML0231;Name=panD;Function=;Product=Probable aspartate-1-decarboxylase precursor PanD (aspartate alpha-decarboxylase);Comments=ML0231, len: 142 aa. Probable panD, aspartate 1-decarboxylase (EC 4.1.1.11), highly similar to PAND_MYCTU|Z95557 panD, aspartate-1-decarboxylase from M. tuberculosis (139 aa), Fasta scores: E(): 0, (82.9% identity in 140 aa overlap); and to several others e.g. Q9X4N0|AF116184 panD, L-aspartate-alpha-decarboxylase precursor from Corynebacterium glutamicum (136 aa), Fasta scores: E(): 9.3e-29, (68.8% identity in 128 aa overlap).;UniProt_AC=Q9CD57;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	322399	323055	.	-	0	Locus=ML0246c;Name=lpqT;Function=;Product=Probable conserved lipoprotein LpqT;Comments=ML0246c, len: 218 aa. Probable lpqT, conserved lipoprotein, similar to Rv1016c|LPQT_MYCTU|P96384 lpqT, probable lipoprotein from M. tuberculosis (226 aa), Fasta scores: E(): 0, (67.1% identity in 213 aa overlap). Also similar to Rv0040c|PR28_MYCTU|P71697 MTC28, proline rich 28 kDa antigen precursor from M. tuberculosis (311 aa), Fasta scores: E(): 1.3e-10, (33.3% identity in 159 aa overlap). Also similar to ML0031 from M. leprae, except at N-terminus. Contains a probable N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CD47;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	293693	296065	.	+	0	Locus=ML0222;Name=ftsH;Function=;Product=Probable membrane-bound protease FtsH (cell division protein);Comments=ML0222, len: 790 aa. Probable ftsH, membrane-bound protease (cell division protein) (EC 3.4.24.-) (see citations below), highly similar to Rv3610c|FTSH_MYCTU|P96942 ftsH, membrane-bound protease from M. tuberculosis (760 aa), Fasta scores: E(): 0, (87.2% identity in 790 aa overlap). Similar to many others e.g. FTSH_ECOLI|P28691 ftsH, cell division protein from Escherichia coli (644 aa), Fasta scores: E(): 0, (49.3% identity in 611 aa overlap). Previously sequenced as O69532|AL023093 (787 aa), Fasta scores: E(): 0, (100.0% identity in 787 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF01434 Peptidase_M41, Peptidase family M41. Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00674 AAA-protein family signature. Belongs to the AAA family of ATPase and peptidase family M41 (zinc metalloproteases). Cofactor: potentially binds one zinc ion.;UniProt_AC=Q9CD58;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	298516	298992	.	+	0	Locus=ML0227;Name=ML0227;Function=;Product=Probable conserved secreted or membrane protein;Comments=ML0227, len: 158 aa. Probable conserved secreted or membrane protein, highly similar to Rv3605c|O06277|AL123456 conserved secreted or membrane protein from M. tuberculosis (158 aa), Fasta scores: E(): 0, (85.4% identity in 158 aa overlap). Previously sequenced as O69527|AL023093 (158 aa), Fasta scores: E(): 0, (100.0% identity in 158 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=O69527;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	300537	301466	.	+	0	Locus=ML0229;Name=ML0229;Function=;Product=Conserved hypothetical protein;Comments=ML0229, len: 309 aa. Conserved hypothetical ala-, leu-rich protein, similar to Rv3603c|O06279|AL123456 hypothetical ala-, leu-rich protein from M. tuberculosis (303 aa), Fasta scores: E(): 0, (67.8% identity in 311 aa overlap). Similar to the N-terminal half of Q9X845|AL049630 hypothetical protein SCE126.02C from Streptomyces coelicolor (420 aa), Fasta scores: E(): 4.1e-24, (36.7% identity in 294 aa overlap). Previously sequenced as O69525|AL023093 (309 aa), Fasta scores: E(): 0, (100.0% identity in 309 aa overlap).;UniProt_AC=O69525;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	365860	366273	.	-	0	Locus=ML0284c;Name=ML0284c;Function=;Product=Conserved hypothetical protein;Comments=ML0284c, len: 137 aa. Conserved hypothetical protein, highly similar to Rv0360c|O06310|AL123456 conserved hypothetical protein from M. tuberculosis (145 aa), Fasta scores: E(): 0, (85.4% identity in 137 aa overlap); and similar to Q9X8R4|AL049754 hypothetical protein SCH10.25C from Streptomyces coelicolor (143 aa), Fasta scores: E(): 8.2e-27, (56.2% identity in 130 aa overlap). Previously sequenced as O69598|AL023514 (137 aa), Fasta scores: E(): 0, (100.0% identity in 137 aa overlap).;UniProt_AC=O69598;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	319965	320564	.	-	0	Locus=ML0244c;Name=pth;Function=;Product=Probable peptidyl-tRNA hydrolase Pth;Comments=ML0244c, len: 199 aa. Probable pth, peptidyl-tRNA hydrolase (EC 3.1.1.29), highly similar to Rv1014c|PTH_MYCTU|P96386 pth, peptidyl-tRNA hydrolase from M. tuberculosis (191 aa), Fasta scores: E(): 0, (77.7% identity in 188 aa overlap). Similar to many e.g. PTH_ECOLI|P23932 pth, peptidyl-tRNA hydrolase from Escherichia coli (194 aa), Fasta scores: E(): 3.7e-22, (37.2% identity in 188 aa overlap). Contains Pfam match to entry PF01195 Pept_tRNA_hydro, Peptidyl-tRNA hydrolase. Contains PS01196 Peptidyl-tRNA hydrolase signature 2. Belongs to the Pth family.;UniProt_AC=Q9CD49;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	321491	321765	.	-	0	Locus=ML0245A;Name=ML0245A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0245A, len:274. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	328067	331741	.	+	0	Locus=ML0252;Name=mfd;Function=Necessary for strand-specific repair. a lesion in the template stand blocks the RNA polymerase complex (RNAp). The RNAp-DNA-RNA complex is specifically recognized by mfd which releases RNAp and the truncated transcript; the mfd may replace RNAp at the lesion site and then recruit the uvrA/B/C repair system.;Product=Probable transcription-repair coupling factor Mfd (trcF);Comments=ML0252, len: 1224 aa. Probable mfd, transcription-repair coupling factor, highly similar to Rv1020|MFD_MYCTU|P96380 mfd, transcription-repair coupling factor from M. tuberculosis (1234 aa), Fasta scores: E(): 0, (84.3% identity in 1229 aa overlap); and similar to many others e.g. MFD_ECOLI|P30958 mfd, transcription-repair coupling factor from Escherichia coli (1148 aa), Fasta scores: E(): 0, (38.1% identity in 1111 aa overlap). Contains Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase. In the N-terminal section; belongs to the uvrB family and in the C-terminal section; belongs to the helicase family. recG subfamily.;UniProt_AC=Q9CD43;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	366385	367263	.	+	0	Locus=ML0285;Name=ML0285;Function=;Product=Probable conserved membrane protein;Comments=ML0285, len: 292 aa. Probable conserved membrane protein, similar to Rv0361|O06311|AL123456 probable conserved membrane protein from M. tuberculosis (275 aa), Fasta scores: E(): 0, (58.6% identity in 292 aa overlap). Previously sequenced as O69599|AL023514 (292 aa), Fasta scores: E(): 0, (100.0% identity in 292 aa overlap). Contains hydrophobic, possible membrane-spanning region.;UniProt_AC=O69599;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	320577	321224	.	-	0	Locus=ML0245c;Name=rplY;Function=;Product=Probable 50S ribosomal protein L25 RplY;Comments=ML0245c, len: 215 aa. Probable rplY, 50s ribosomal protein L25, highly similar to Rv1015c|RL25_MYCTU|P96385 rplY, 50S ribosomal protein L25 from M. tuberculosis (215 aa), Fasta scores: E(): 0, (73.9% identity in 218 aa overlap). Similar to many others e.g. RL25_ECOLI|P02426 rplY, 50S ribosomal protein L25 from Escherichia coli (94 aa), Fasta scores: E(): 0.00054, (33.7% identity in 89 aa overlap). Contains Pfam match to entry PF01386 Ribosomal_L25p, Ribosomal L25p family. Belongs to the L25P family of ribosomal proteins.;UniProt_AC=Q9CD48;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	335805	336308	.	+	0	Locus=ML0257;Name=ML0257;Function=;Product=Conserved hypothetical protein;Comments=ML0257, len: 167 aa. Conserved hypothetical protein, highly similar to Rv1025|P96375|AL123456 conserved hypothetical protein from M. tuberculosis (155 aa), Fasta scores: E(): 0, (85.1% identity in 154 aa overlap). Also similar to other hypothetical proteins e.g. Q9F2Q5 conserved hypothetical protein from Streptomyces coelicolor A3(2) (186 aa), Fasta scores: E(): 2e-36, (65.0% identity in 143 aa overlap).;UniProt_AC=Q9CD40;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	336305	337258	.	+	0	Locus=ML0258;Name=ML0258;Function=;Product=Conserved hypothetical protein;Comments=ML0258, len: 317 aa. Conserved hypothetical protein. Highly similar to Rv1026|P96374|AL123456 conserved hypothetical protein from M. tuberculosis (319 aa), Fasta scores: E(): 0, (77.6% identity in 321 aa overlap). Similar to many bacterial hypothetical proteins and shows weak similarity to N-terminal half of PPX_ECOLI|P29014 ppx, exopolyphosphatase from Escherichia coli (512 aa), Fasta scores: E(): 6.8e-07, (25.3% identity in 297 aa overlap). Also shows weak similarity to ML2434.;UniProt_AC=O69585;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1337940	1338383	.	+	0	Locus=ML1147;Name=ML1147;Function=;Product=CONSERVED HYPOTHETICAL SECRETED PROTEIN;Comments=ML1147, len: 147 aa. Conserved hypothetical secreted protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD12_MYCLE (P53432) (147 aa), Fasta scores: E(): 0, 100.0% identity in 147 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1312 TR:YD12_MYCTU. Contains a possible N-terminal signal sequence.;UniProt_AC=P53432;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	354105	354860	.	+	0	Locus=ML0270;Name=ML0270;Function=;Product=Beta-lactamase-like protein;Comments=ML0270, len: 251 aa. Beta-lactamase-like protein, highly similar to others from Mycobacteria e.g. Rv0406c|O86336|AL123456 Beta-lactamase-like protein from M. tuberculosis (272 aa), Fasta scores: E(): 0, (74.9% identity in 243 aa overlap); Q9XC16|AF152394 bllP, beta-lactamase-like protein from Mycobacterium avium (247 aa), Fasta scores: E(): 0, (73.7% identity in 243 aa overlap). Shows similarity to other members of the metallo-beta-lactamase superfamily. Previously sequenced as O69590|AL023514 (251 aa), Fasta scores: E(): 0, (100.0% identity in 251 aa overlap). Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily.;UniProt_AC=O69590;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	354849	355220	.	-	0	Locus=ML0271c;Name=ML0271c;Function=;Product=Probable conserved transmembrane protein;Comments=ML0271c, len: 123 aa. Probable conserved transmembrane protein, similar to Rv0401|P95210|AL123456 probable conserved transmembrane protein from M. tuberculosis (123 aa), Fasta scores: E(): 1.9e-32, (66.9% identity in 121 aa overlap). Similar to a region of AAF69175|AC007915 hypothetical protein F27F5.3 from Arabidopsis thaliana (261 aa), Fasta scores: E(): 1.5e-06, (30.8% identity in 120 aa overlap). Previously sequenced as O69591|AL023514 (122 aa), Fasta scores: E(): 0, (100.0% identity in 122 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CCX5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	361297	361953	.	-	0	Locus=ML0279c;Name=ML0279c;Function=;Product=Conserved hypothetical protein;Comments=ML0279c, len: 218 aa. Conserved hypothetical protein, highly similar to Rv0356c|O06307|AL123456 conserved hypothetical protein from M. tuberculosis (214 aa), Fasta scores: E(): 0, (73.4% identity in 214 aa overlap); and other bacterial hypothetical proteins. Previously sequenced as O69594|AL023514 (218 aa), Fasta scores: E(): 0, (99.5% identity in 218 aa overlap). Similar to ML0457c a possible pseudogene similar to M. tuberculosis Rv0356c.;UniProt_AC=O69594;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	363432	364121	.	+	0	Locus=ML0281;Name=ML0281;Function=;Product=Conserved hypothetical protein;Comments=ML0281, len: 229 aa. Conserved hypothetical protein, similar to Rv0358|O06308|AL123456 conserved hypothetical protein from M. tuberculosis (215 aa), Fasta scores: E(): 0, (62.4% identity in 229 aa overlap). Previously sequenced as O69596|AL023514 (229 aa), Fasta scores: E(): 0, (99.6% identity in 229 aa overlap).;UniProt_AC=O69596;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	364916	365722	.	+	0	Locus=ML0283;Name=ML0283;Function=;Product=Possible cation-efflux transporter component;Comments=ML0283, len: 268 aa. Possible cation-efflux transporter component, similar to others  e.g. CZCD_ALCEU|P13512 czcD, cobalt-zinc-cadmium resistance protein from Alcaligenes eutrophus (316 aa), Fasta scores: E(): 3.8e-22, (36.4% identity in 209 aa overlap); and Q9X7Q7 putative efflux protein from Streptomyces coelicolor A3(2) (312 aa). Previously sequenced as O69597|AL023514 (256 aa), Fasta scores: E(): 0, (100.0% identity in 256 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Beyond codon 220 (approx.) GC frameplot and codon usage plots indicate a possible frame change. Similarity to characterised transporter components ends at this point. This suggests that the ORF may have suffered a disruption and therefore not encode a functional product. Contains Pfam match to entry PF01545 Cation_efflux, Cation efflux family.;UniProt_AC=Q9CCX3;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	563633	564538	.	+	0	Locus=ML0466;Name=ML0466;Function=;Product=Possible secreted protein;Comments=ML0466, len: 301 aa. Possible secreted protein. Similar to Q9X7W9|AL049485|SC6A5.23  hypothetical protein from Streptomyces coelicolor (261 aa), Fasta scores: E(): 9.5e-26, (36.4% identity in 253 aa overlap). Previously sequenced as O07156|Z96801 (301 aa), Fasta scores: E(): 0, (99.7% identity in 301 aa overlap). Contains a possible N-terminal signal sequence.;UniProt_AC=O07156;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	382835	383542	.	+	0	Locus=ML0300;Name=thiE;Function=Involved in thiamine biosynthesis. Condenses 4-methy-(beta-hydroxyethyl)-thiazole monophosphate (THZ-P) and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) [Catalytic activity: 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-4-methyl-5-(2-phosphonooxyethyl)-thiazole = diphosphate + thiamine monophosphate].;Product=Probable thiamine-phosphate pyrophosphorylase ThiE (TMP pyrophosphorylase) (TMP-PPase) (Thiamine-phosphate synthase).;Comments=ML0300, len: 235 aa. Probable thiE, thiamin phosphate pyrophosphorylase (EC 2.5.1.3), highly similar to Rv0414c|THIE_MYCTU|P96260 probable thiE, thiamin phosphate pyrophosphorylase from M. tuberculosis (222 aa), Fasta scores: E(): 0, (78.9% identity in 223 aa overlap). Similar to many other e.g. THIE_ECOLI|P30137 thiE, thiamine-phosphate pyrophosphorylase from Escherichia coli (211 aa), Fasta scores: E(): 5e-10, (38.7% identity in 199 aa overlap). Previously sequenced as THIE_MYCLE|Q9ZBL5 (235 aa), Fasta scores: E(): 0, (99.6% identity in 235 aa overlap). Belongs to the TMP-PPase family.;UniProt_AC=Q9ZBL5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	489916	490428	.	-	0	Locus=ML0394c;Name=ML0394c;Function=;Product=Hypothetical protein;Comments=ML0394c, len: 170 aa. Hypothetical Unknown protein. Possible CDS suggested by GC frameplot and codon usage plots. Some similarity with bacterial methyltransferases e.g. Q98K44 Probable sterol methyltransferase from Mesorhizobium loti (280 aa), Fasta scores: E(): 0, (30.8% identity in 107 aa overlap).;UniProt_AC=Q9CCV0;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	589653	589997	.	+	0	Locus=ML0486;Name=yajC;Function=;Product=Probable conserved membrane protein secretion factor YajC;Comments=ML0486, len: 114 aa. Probable yajC, a conserved membrane protein secretion factor,  (see Braunstein & Belisle 2000), highly similar to YP88_MYCTU|Q50633|Rv2588c Probable yajC, secretion factor from M. tuberculosis (115 aa), Fasta scores: E(): 7e-29, (77.0% identity in 100 aa overlap); and CAD94804|Mb2619c from M. bovis (115 aa). Similar to other bacterial proteins e.g. Q9L292|SCL2.07c putative secreted protein from Streptomyces coelicolor (169 aa), Fasta scores: E(): 7.3e-08, (35.8% identity in 120 aa overlap). Previously sequenced as YP88_MYCLE|Q49647 (114 aa), Fasta scores: E(): 0, (100.0% identity in 114 aa overlap). Contains a possible N-terminal signal sequence.;UniProt_AC=Q49647;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	367279	368316	.	-	0	Locus=ML0286c;Name=fba;Function=;Product=Probable fructose bisphosphate aldolase Fba;Comments=ML0286c, len: 345 aa. Probable fba (alternate gene name: fda), fructose bisphosphate aldolase (EC 4.1.2.13), highly similar to Rv0363c|ALF_MYCTU|O06313 fba, fructose bisphosphate aldolase from M. tuberculosis (344 aa), Fasta scores: E(): 0, (87.7% identity in 342 aa overlap). Similar to many e.g. ALF_CORGL|P19537 fructose bisphosphate aldolase from Corynebacterium glutamicum (343 aa), Fasta scores: E(): 0, (72.8% identity in 342 aa overlap). Previously sequenced as ALF_MYCLE|O69600 (345 aa), Fasta scores: E(): 0, (100.0% identity in 345 aa overlap). Contains Pfam match to entry PF01116 F_bP_aldolase, Fructose-bisphosphate aldolase class-II. Contains PS00806 Fructose-bisphosphate aldolase class-II signature 2. Contains PS00602 Fructose-bisphosphate aldolase class-II signature 1. Belongs to class II fructose-bisphosphate aldolase family. Cofactor: zinc.;UniProt_AC=O69600;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	77709	82292	.	+	0	Locus=ML0061;Name=gltB;Function=;Product=Probable ferredoxin-dependent glutamate synthase (large subunit) GltB (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate synthase) (NADPH-GOGAT);Comments=ML0061, len: 1527 aa. Probable gltB, ferredoxin-dependent glutamate synthase large subunit (EC 1.4.1.13), equivalent to Rv3859c|P96218|Al123456 probable ferredoxin-dependent glutamate synthase from M. tuberculosis (1527 aa), Fasta scores: E(): 0, (90.2% identity in 1527 aa overlap); and similar to other glutamate synthases e.g. GLTB_SYNY3|P55037  gltB, ferredoxin-dependent glutamate synthase 1 from Synechocystis sp. (1550 aa), Fasta scores: E(): 0, (57.2% identity in 1525 aa overlap). Contains Pfam match to entry PF01493 DUF14, Domain of unknown function. Contains Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase. Contains PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.;UniProt_AC=Q9CDD5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	296082	296699	.	+	0	Locus=ML0223;Name=folE;Function=;Product=Probable GTP cyclohydrolase I FolE (GTP-CH-I);Comments=ML0223, len: 205 aa. Probable folE (alternate gene name: gchA), GTP cyclohydrolase I (EC 3.5.4.16), highly similar to Rv3609c|GCH1_MYCTU|O06273 folE, GTP cyclohydrolase I from M. tuberculosis (202 aa), Fasta scores: E(): 0, (82.0% identity in 205 aa overlap). Similar to many others e.g. GCH1_BACSU|P19465 mtrA, GTP cyclohydrolase I from Bacillus subtilis (190 aa), Fasta scores: E(): 0, (59.5% identity in 190 aa overlap). Previously sequenced as GCH1_MYCLE|O69531 (205 aa), Fasta scores: E(): 0, (100.0% identity in 205 aa overlap). Contains Pfam match to entry PF01227 GTP_cyclohydroI, GTP cyclohydrolase I. Contains PS00859 GTP cyclohydrolase I signature 1. Contains PS00860 GTP cyclohydrolase I signature 2. Belongs to the GTP cyclohyrolase I family.;UniProt_AC=O69531;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	313910	314698	.	+	0	Locus=ML0239;Name=tatD;Function=;Product=Probable deoxyribonuclease TatD;Comments=ML0239, len: 262 aa. Probable tatD (alternate gene name: yjjV), deoxyribonuclease (EC 3.1.21.-), component of twin arginine translocation protein export system (see citation below for more information). Highly similar to Rv1008|O08343|AL123456 tatD, deoxyribonuclease from M. tuberculosis (264 aa), Fasta scores: E(): 0, (82.3% identity in 260 aa overlap). Similar to members of the TatD family e.g. Bacillus subtilis yabD, conserved hypothetical protein, SW:YABD_BACSU (P37545) (255 aa), Fasta scores: E(): 0, 41.0% identity in 261 aa overlap. Contains Pfam match to entry PF01026 UPF0006, Metalloenzyme of unknown function. Contains PS01137 TatD deoxyribonuclease family signature 1, and PS01091 TatD deoxyribonuclease family signature 3.;UniProt_AC=Q9CD54;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	131869	133422	.	+	0	Locus=ML0102;Name=accD4;Function=;Product=Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase);Comments=ML0102, len: 517 aa. Probable accD4, propyonyl-CoA carboxylase beta chain 4 (EC 6.4.1.3), highly similar to many e.g. Rv3799c|O53578|AL123456 probable accD4, propyonyl-CoA carboxylase from M. tuberculosis (522 aa), Fasta scores: E(): 0, (91.2% identity in 512 aa overlap); and Q9X4K7|AF113605 propionyl-CoA carboxylase complex B subunit from Streptomyces coelicolor (530 aa), Fasta scores: E(): 0, (48.2% identity in 521 aa overlap). Also similar to ML0731 and ML1657 from M. leprae. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain.;UniProt_AC=Q9CDB0;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	180027	182150	.	+	0	Locus=ML0134;Name=fadD22;Function=;Product=Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase);Comments=ML0134, len: 707 aa. Probable fadD22, fatty-acid-CoA synthetase (EC 6.2.1.-). Highly similar to many e.g. Rv2948c|P96283|AL123456 probable fadD22, fatty-acid-CoA synthase from M. tuberculosis (705 aa), Fasta scores: E(): 0, (75.9% identity in 705 aa overlap); and similar to Q59760|L42322 badA, benzoate-coenzyme A ligase from Rhodopseudomonas palustris   (521 aa), Fasta scores: E(): 0, (31.4% identity in 494 aa overlap). Also similar to ML1051, ML1994, ML2257 and ML2546 from M. leprae. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme.;UniProt_AC=Q9CD82;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	342403	343857	.	-	0	Locus=ML0262A;Name=ML0262A;Function=;Product=PPE15; PPE family protein(pseudogene);Comments=ML0262A, len:1454. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	124599	126506	.	+	0	Locus=ML0100;Name=fadD32;Function=;Product=Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase);Comments=ML0100, len: 635 aa. Probable fadD32, fatty-acid-CoA synthetase (EC 6.2.1.-), highly similar to several probable fatty-acid-CoA synthases from M. tuberculosis e.g. Rv3801c|O53580|AL123456 fadD32 (637 aa), Fasta scores: E(): 0, (93.2% identity in 632 aa overlap). Also similar to P71495|U75685 acyl-CoA synthase from Mycobacterium bovis BCG ORF3 (582 aa), Fasta scores: E(): 0, (36.8% identity in 581 aa overlap); and to domains of polyketide synthases e.g. Q50857|U24657 safB, saframycin Mx1 synthetase B from Myxococcus xanthus (1770 aa), Fasta scores: E(): 0, (36.4% identity in 605 aa overlap). And similar to ML0132, ML0138, ML1234 and ML2358 from M. leprae. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme.;UniProt_AC=Q9CDB2;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	121157	122149	.	+	0	Locus=ML0097;Name=fbpA;Function=Involved in cell wall mycoloylation. Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity.;Product=Secreted antigen 85A FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A);Comments=ML0097, len: 330 aa. Probable fbpA, precursor of the 85-A antigen (fibronectin-binding protein A) (EC 2.3.1.-) (see citations below), highly similar to Rv3804|A85A_MYCTU|P17944 fbpA, antigen 85-A precursors from M. tuberculosis (338 aa), Fasta scores: E(): 0, (83.0% identity in 329 aa overlap). Also similar to the B- and C- proteins of the mycobacterial antigen 85 complexes. Similar to N-terminal region of CSP1_CORGL|Q01377 PS1 protein precursor from Corynebacterium glutamicum csp1 (657 aa), Fasta scores: E(): 5.2e-31, (38.6% identity in 290 aa overlap). Also similar to ML0098, ML2028 and ML2655 from M. leprae. Previously sequenced as A85A_MYCLE|Q05861 (330 aa), Fasta scores: E(): 0, (100.0% identity in 330 aa overlap). Contains probable N-terminal signal sequence. Contains Pfam match to entry PF00756 Esterase, Putative esterase.;UniProt_AC=Q05861;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	275049	276008	.	+	0	Locus=ML0204;Name=galE1;Function=;Product=Probable UDP-glucose 4-epimerase GalE1 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase);Comments=ML0204, len: 319 aa. Probable galE1, UDP-glucose 4-epimerase (EC 5.1.3.2) (see citations below), highly similar to Rv3634c|O06373|AL123456 galE1, UDP-glucose 4-epimerase from M. tuberculosis (314 aa), Fasta scores: E(): 0, (86.1% identity in 309 aa overlap). Similar to other bacterial sugar-nucleotide dehydratases (many putative) e.g. Q9ZGH3|AF079762 desIV, TDP-glucose-4,6-dehydratase from Streptomyces venezuelae (337 aa), Fasta scores: E(): 1.4e-24, (34.3% identity in 321 aa overlap). Previously sequenced as O69544|AL023093 (319 aa), Fasta scores: E(): 0, (100.0% identity in 319 aa overlap). Also similar to ML1964 from M. leprae. Contains Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase family. Contains PS00061 Short-chain dehydrogenases/reductases family signature. Belongs to the sugar epimerase family. Note that previously known as rmlB2, a DTDP-glucose 4,6-dehydratase (EC 4.2.1.46) (see third citation).;UniProt_AC=O69544;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	394458	395162	.	+	0	Locus=ML0308;Name=ML0308;Function=;Product=Conserved hypothetical protein;Comments=ML0308, len: 234 aa. Conserved hypothetical protein, some similarity to hypothetical proteins from methanobacteria e.g. O27829|AE000934 hypothetical protein MTH1801 from Methanobacterium thermoautotrophicum (224 aa), Fasta scores: E(): 3.6e-24, (39.3% identity in 219 aa overlap); and Y045_METJA|Q60353 hypothetical protein MJ0045 from Methanococcus jannaschii (221 aa), Fasta scores: E(): 4e-17, (30.5% identity in 220 aa overlap). Previously sequenced as Q9ZBM1|AL035159 (234 aa), Fasta scores: E(): 0, (100.0% identity in 234 aa overlap).;UniProt_AC=Q9ZBM1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	268857	270449	.	-	0	Locus=ML0201c;Name=ML0201c;Function=;Product=Probable conserved transmembrane protein;Comments=ML0201c, len: 530 aa. Probable conserved transmembrane protein, highly similar to Rv3645|O06362|AL123456 probable transmembrane protein from M. tuberculosis (549 aa), Fasta scores: E(): 0, (85.3% identity in 530 aa overlap); and to several other putative membrane proteins from M. tuberculosis. Shares regions of similarity with adenylate cyclases e.g. P94180|D89622 cyaA, adenylate cyclase from Anabaena sp. (strain PCC 7120) (735 aa), Fasta scores: E(): 1.5e-16, (33.3% identity in 228 aa overlap). Previously sequenced as O69547|AL023093 (530 aa), Fasta scores: E(): 0, (99.8% identity in 530 aa overlap). Also similar to ML1948c a possible pseudogene similar to M. tuberculosis Rv3645. Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF00672 DUF5, Domain found in bacterial signal proteins. Contains 2 Pfam matches to entry PF00211 guanylate_cyc, Adenylate and Guanylate cyclase catalytic domain.;UniProt_AC=O69547;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	5229	7265	.	+	0	Locus=ML0005;Name=gyrB;Function=DNA Gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. This DNA Gyrase is made up of two chains. The A chain is responsible for DNA breakage and rejoining and the B chain catalyzes ATP hydrolysis [Catalytic activity: ATP-dependent breakage, passage and rejoining of double-stranded DNA].;Product=Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase);Comments=ML0005, len: 678 aa. Probable gyrB, DNA gyrase subunit B (EC 5.99.1.3) (see citations below). Highly similar to other Mycobacterial DNA GYRASES SUBUNIT B e.g. Rv0005|GYRB_MYCTU|P41514 from M. tuberculosis (686 aa), Fasta scores: E(): 0, (87.5% identity in 678 aa overlap); and GYRB_MYCSM|P48355 from Mycobacterium smegmatis (675 aa), Fasta scores: E(): 0, (85.0% identity in 678 aa overlap). Previously sequenced as GYRB_MYCLE|Q59533 (697 aa), Fasta scores: E(): 0, (100.0% identity in 678 aa overlap). Contains Pfam match to entry PF00986 DNA_gyraseB_C, DNA gyrase B subunit, carboxyl terminus. Contains Pfam match to entry PF00204 DNA_topoisoII, DNA topoisomerase II (N-terminal region). Contains PS00177 DNA topoisomerase II signature. Belongs to the type II Topoisomerase family.;UniProt_AC=Q59533;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	317042	317977	.	+	0	Locus=ML0242;Name=ispE;Function=Thought to be involved in deoxyxylulose-5-phosphate pathway (DXP) of isoprenoid biosynthesis (at the fourth step). Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. [Catalytic activity: ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol].;Product=Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase);Comments=ML0242, len: 311 aa. Probable ispE, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.-), highly similar to Rv1011|IPK_MYCTU|O05596 ispE, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from M. tuberculosis (306 aa), Fasta scores: E(): 0, (87.5% identity in 303 aa overlap). Similar to many e.g. IPK_ECOLI|P24209 Escherichia coli isopentenyl monophosphate kinase (283 aa), Fasta scores: E(): 1.3e-13, (35.6% identity in 202 aa overlap). Belongs to the IspE family.;UniProt_AC=Q9CD51;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	255125	255742	.	-	0	Locus=ML0190c;Name=ML0190c;Function=;Product=Conserved hypothetical protein;Comments=ML0190c, len: 205 aa. Conserved hypothetical protein, highly similar to Rv1000c conserved hypothetical protein from M. tuberculosis (205 aa). Also similar to conserved hypothetical proteins in various bacteria e.g. AL357613|AL357613_12 from Streptomyces coelicolor (210 aa), fasta scores: E(): 2.4e-44, (55.1% identity in 205 aa overlap); and AE003963|AE003963_5 from Xylella fastidiosa (200 aa), FASTA scores: E(): 9.7e-14, (39.9% identity in 188 aa overlap). Weak similarity to proteins involved in DNA repair;UniProt_AC=Q9CD62;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	303740	305263	.	+	0	Locus=ML0233;Name=lysS;Function=;Product=Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase);Comments=ML0233, len: 507 aa. Probable lysS, lysyl-tRNA synthetase 1 (EC 6.1.1.6), highly similar to Rv3598c|SYK_MYCTU|O06284 lysS, probable lysyl-tRNA synthase from M. tuberculosis (505 aa), Fasta scores: E(): 0, (85.4% identity in 501 aa overlap). Similar to many other bacterial lysyl-tRNA synthetases e.g. SYK2_ECOLI|P14825 from Escherichia coli (504 aa), Fasta scores: E(): 0, (38.8% identity in 497 aa overlap). Also similar to the C-terminal half of ML1393 from M. leprae. Contains Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N). Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. Belongs to class-II aminoacyl-tRNA synthetase family.;UniProt_AC=P46861;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	166949	167389	.	-	0	Locus=ML0124c;Name=ML0124c;Function=;Product=Conserved hypothetical protein;Comments=ML0124c, len: 146 aa. Conserved hypothetical protein, shows weak similarity to Rv2186c|O53519|AL123456 conserved hypothetical protein from M. tuberculosis (129 aa), Fasta scores: E(): 3.7e-06, (27.5% identity in 131 aa overlap); and to Q9X7Y8|AL049497 hypothetical protein SC6G10.02C from Streptomyces coelicolor (144 aa), Fasta scores: E(): 7e-05, (21.9% identity in 137 aa overlap). Also similar to ML2629 and shows weaker similarity to ML0889 from M. leprae. Previously sequenced as O06090|Z95398 (156 aa), Fasta scores: E(): 0, (70.1% identity in 144 aa overlap).;UniProt_AC=Q9CD92;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	517645	518277	.	+	0	Locus=ML0418;Name=ML0418;Function=;Product=Possible oxidoreductase;Comments=ML0418, len: 210 aa. Possible oxidoreductase (EC 1.-.-.-), highly similar to Rv3368c|O50397|AL123456 possible oxidoreductase from M. tuberculosis (214 aa), Fasta scores: E(): 0, (81.9% identity in 210 aa overlap). Shows weak similarity NOX_THETH|X60110) nox, NADH dehydrogenase from Thermus aquaticus (205 aa), Fasta scores: E(): 0.00023, (28.8% identity in 212 aa overlap); and O30106|AF0131 putative NAD(P)H-flavin oxidoreductase from Archaeoglobus fulgidus (194 aa). Previously sequenced as O07697|Z97179 (210 aa), Fasta scores: E(): 0, (99.5% identity in 210 aa overlap). Also similar to ML2006 a possible pseudogene similar to M. tuberculosis Rv3368c. Contains Pfam match to entry PF00881 Nitroreductase, Nitroreductase family. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign.;UniProt_AC=O07697;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	248102	249376	.	+	0	Locus=ML0183;Name=moeA1;Function=;Product=Probable molybdopterin biosynthesis protein MoeA1;Comments=ML0183, len: 424 aa. Probable moeA1, molybdopterin biosynthesis protein, highly similar to Rv0994|MOEA_MYCTU|O05577  moeA, probable molybdopterin biosynthesis protein from M. tuberculosis (426 aa), Fasta scores: E(): 0, (88.3% identity in 426 aa overlap). Similar to many e.g. MOEA_ECOLI|P12281 moeA, molybdopterin biosynthesis protein from Escherichia coli   (411 aa), Fasta scores: E(): 3.3e-23, (31.4% identity in 392 aa overlap). Previously sequenced as Q9Z5G0|AL035500 (424 aa), Fasta scores: E(): 0, (99.8% identity in 424 aa overlap). Contains Pfam match to entry PF00994 MoCF_biosynth, Molybdenum cofactor biosynthesis protein. Note that previously known as moeA.;UniProt_AC=Q9Z5G0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	240531	241217	.	+	0	Locus=ML0174;Name=mprA;Function=;Product=Mycobacterial persistence regulator MrpA (two-component response transcriptional regulatory protein);Comments=ML0174, len: 228 aa. Probable mprA, mycobacterial persistence regulator, a two-component response regulator whose expression is required for entry and maintenance of persistent infections (see citation below), equivalent to Rv0981|O53894|AL123456 mprA, regulator part from a two-component response regulator system from M. tuberculosis (230 aa), Fasta scores: E(): 0, (94.3% identity in 228 aa overlap); and several other putative two-component response regulators e.g. COPR_PSESM|Q02540 copR, transcriptional activator protein involved in activation of copper resistance from Pseudomonas syringae (227 aa), Fasta scores: E(): 6.4e-32, (43.9% identity in 223 aa overlap). Also similar to ML0773, ML1286, ML2123 and ML2439 from M. leprae. Previously sequenced as Q9Z5G8|AL035500 (253 aa), Fasta scores: E(): 0, (100.0% identity in 228 aa overlap). Contains Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal. Contains Pfam match to entry PF00072 response_reg, Response regulator receiver domain.;UniProt_AC=Q9CD68;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	98425	99393	.	+	0	Locus=ML0078;Name=pheA;Function=;Product=Possible prephenate dehydratase PheA;Comments=ML0078, len: 322 aa. Possible pheA, prephenate dehydratase (EC 4.2.1.51) (see citation below), highly similar to Rv3838c|P96240|AL123456 pheA, prephenate dehydratase from M. tuberculosis (321 aa), Fasta scores: E(): 0, (83.9% identity in 311 aa overlap). Similar to PHEA_AMYME|Q44104 pheA, prephenate dehydratase from Amycolatopsis methanolica (304 aa), Fasta scores: E(): 0, (44.4% identity in 315 aa overlap). Contains Pfam match to entry PF01842 ACT, ACT domain. Contains Pfam match to entry PF00800 PDT, Prephenate dehydratase. Contains PS00858 Prephenate dehydratase signature 2.;UniProt_AC=Q9CDC4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2375712	2376425	.	-	0	Locus=ML1988c;Name=ML1988c;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN;Comments=ML1988c, len: 237 aa. Probable conserved membrane protein. Similar to M. tuberculosis probable  membrane protein Rv0093c SW:Y093_MYCTU (Q10890) E():0 70.3% identity in 236 aa. Contains possible membrane spanning hydrophobic domains. Note lacks the N-terminal 46 aa of the M. tuberculosis protein.;UniProt_AC=Q9CBG8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	19001	20869	.	-	0	Locus=ML0016c;Name=pknB;Function=;Product=Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B);Comments=ML0016c, len: 622 aa. Probable pknB, transmembrane serine/threonine-protein kinase (EC 2.7.1.-) (see citations below), highly similar to Rv0014c|PKNB_MYCTU|P71584 pknB, transmembrane serine/threonine protein kinase from M. tuberculosis (626 aa), Fasta scores: E(): 0, (86.3% identity in 626 aa overlap); and similar to Q9ZFS8|AF094711 pksC, serine/threonine protein kinase from Streptomyces coelicolor (556 aa), Fasta scores: E(): 0, (47.8% identity in 297 aa overlap). Also similar to ML0017 and ML0897 and to part of ML0304 from M. leprae. Previously sequenced as PKNB_MYCLE|P54744 (622 aa), Fasta scores: E(): 0, (99.7% identity in 622 aa overlap).  Contains Pfam match to entry PF00069 pkinase, Eukaryotic protein kinase domain. Contains PS00108 Serine/Threonine protein kinases active-site signature. Contains PS00107 Protein kinases ATP-binding region signature.;UniProt_AC=P54744;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	223972	224619	.	+	0	Locus=ML0160;Name=purN;Function=;Product=Probable 5'-phosphoribosylglycinamide formyltransferase PurN (garT) (gar transformylase) (5'-phosphoribosylglycinamide transformylase);Comments=ML0160, len: 215 aa. Probable purN, 5'-phosphoribosylglycinamide formyltransferase (EC 2.1.2.2), highly similar to Rv0956|P71554|AL123456 purN, 5'-phosphoribosylglycinamide formyltransferase from M. tuberculosis (215 aa), Fasta scores: E(): 0, (79.4% identity in 214 aa overlap). Similar to many e.g. TQ9RAJ6|AF191543 purN, phosphoribosylglycinamide formyltransferase I from Mycobacterium avium subsp. paratuberculosis (209 aa), Fasta scores: E(): 0, (81.6% identity in 207 aa overlap). Previously sequenced as Q9Z5H6|AL035500 (215 aa), Fasta scores: E(): 0, (99.5% identity in 215 aa overlap). Contains Pfam match to entry PF00551 formyl_transf, Formyl transferase.;UniProt_AC=Q9Z5H6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	152783	153613	.	-	0	Locus=ML0112c;Name=rfbD;Function=;Product=Probable lipopolysaccharide transport integral membrane ABC transporter RfbD;Comments=ML0112c, len: 276 aa. Probable rfbD, polysaccharide-transport integral membrane protein ABC transporter (see first citation below), involved in O-antigen/lipopolysaccharides (LPS) transport, highly similar to Rv3783|P72049|AL123456 rfbD, polysaccharide-transport integral membrane protein ABC transporter from M. tuberculosis (280 aa) Fasta scores: E(): 0, (84.3% identity in 280 aa overlap). Similar to RFBD_YEREN|Z18920 rfbD, O-antigen export system permease protein from Yersinia enterocolitica (259 aa)(see second citation below), Fasta scores: E(): 2.9e-32, (28.2% identity in 259 aa overlap); and to other membrane proteins involved in lipopolysaccharide transport. Contains Pfam match to entry PF01061 ABC2_membrane, ABC-2 type transporter. Belongs to the ABC-2 subfamily of integral membrane proteins.;UniProt_AC=Q9CDA2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	424868	425728	.	-	0	Locus=ML0335c;Name=ML0335c;Function=;Product=Possible ABC-transporter transmembrane protein;Comments=ML0335c, len: 286 aa. Possible ABC-transporter transmembrane protein. Similar in part to Rv2060|O86339|AL123456 conserved integral membrane protein from M. tuberculosis (133 aa), Fasta scores: E(): 0, (80.3% identity in 132 aa overlap). Similar, except N-terminal approx. 100 aa to many bacterial ABC transporters e.g. O33704|Z71552 adcB, putative ABC metal permease from Streptococcus pneumoniae (268 aa), Fasta scores: E(): 2.5e-15, (26.6% identity in 263 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF00950 ABC-3, ABC 3 transport family.;UniProt_AC=Q9CCW1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2514419	2514589	.	-	0	Locus=ML2114c;Name=ML2114c;Function=;Product=conserved hypothetical protein;Comments=ML2114c, len: 56 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 6.4 kda protein Rv0909 TR:O05901 (EMBL:Z95210) fasta scores: E(): 1.8e-07, 61.9% in 42 aa, and to Streptomyces coelicolor hypothetical 9.9 kda protein TR:O69965 (EMBL:AL022268) fasta scores: E(): 0.038, 41.3% in 46 aa.;UniProt_AC=Q9CBE3;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	314948	316075	.	+	0	Locus=ML0240;Name=rpfB;Function=;Product=Probable resuscitation-promoting factor RpfB;Comments=ML0240, len: 375 aa. Probable rpfB, resuscitation-promoting factor (see citation below), highly similar to Rv1009|O05594|AL123456 probable rpfB, resuscitation-promoting factor from M. tuberculosis (362 aa), Fasta scores: E(): 0, (82.3% identity in 361 aa overlap). The C-terminus is similar to a region conserved in many bacterial hypothetical proteins e.g. Q9RKD7|AL132674 hypothetical protein SCE87.01C from Streptomyces coelicolor  (330 aa), Fasta scores: E(): 3.2e-14, (33.8% identity in 225 aa overlap). Also similar in part to other M. tuberculosis probable resuscitation-promoting factor e.g. Rv0867c|RPFA, Rv1884c|RPFC, and Rv2389c|RPFD The C-terminus is similar to regions of ML2030 and ML2151.;UniProt_AC=Q9CD53;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	102122	103375	.	+	0	Locus=ML0082;Name=serS;Function=;Product=Probable seryl-tRNA synthetase SerS (serine--tRNA ligase) (SERRS) (serine translase);Comments=ML0082, len: 417 aa. Probable serS, seryl-tRNA synthetase (EC 6.1.1.11), highly similar to Rv3834c|SYS_MYCTU|P96244 serS, seryl-tRNA synthetase from M. tuberculosis (419 aa), Fasta scores: E(): 0, (85.8% identity in 416 aa overlap). Similar to SYS_STAAU|Y09924 serS, seryl-tRNA synthetase from Staphylococcus aureus (428 aa), Fasta scores: E(): 0, (36.8% identity in 418 aa overlap). Contains Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II (G, H, P, S and T). Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. Belongs to the class-II aminoacyl-tRNA synthetase family.;UniProt_AC=Q9CDC1;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	219659	220561	.	+	0	Locus=ML0156;Name=sucD;Function=;Product=Probable succinyl-CoA synthetase (alpha chain) SucD (SCS-alpha);Comments=ML0156, len: 300 aa. Probable sucD, succinyl-CoA synthetase, alpha chain (EC 6.2.1.5), highly similar to Rv0952|SUCD_MYCTU|P71558 sucD, succinyl-CoA synthetase, alpha chain from M. tuberculosis (303 aa), Fasta scores: E(): 0, (86.3% identity in 300 aa overlap). Similar to many e.g. SUCD_ECOLI|P07459 sucD, succinyl-CoA synthase, alpha chain from Escherichia coli (288 aa), Fasta scores: E(): 0, (50.3% identity in 298 aa overlap). Previously sequenced as Q9S372|AL035500 (300 aa), Fasta scores: E(): 0, (100.0% identity in 300 aa overlap). Contains Pfam match to entry PF00549 ligase-CoA, CoA-ligases. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. Contains PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1.;UniProt_AC=Q9S372;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	379127	379966	.	+	0	Locus=ML0295;Name=thiD;Function=;Product=Probable phosphomethylpyrimidine kinase ThiD;Comments=ML0295, len: 279 aa. Probable thiD, phosphomethylpyrimidine kinase (EC 2.7.4.7), highly similar to Rv0422c|THID_MYCTU|P96268 thiD, phosphomethylpyrimidine kinase from M. tuberculosis (265 aa), Fasta scores: E(): 0, (77.8% identity in 266 aa overlap). Similar to many others e.g. THID_ECOLI|P76422 thiD, phosphomethylpyrimidine kinase from Escherichia coli (266 aa), Fasta scores: E(): 3.2e-29, (38.4% identity in 263 aa overlap). Previously sequenced as THID_MYCLE|Q9ZBL1 (279 aa), Fasta scores: E(): 0, (99.6% identity in 279 aa overlap). Belongs to the ThiD family.;UniProt_AC=Q9ZBL1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2414171	2414238	.	-	0	Locus=ML2022A;Name=ML2022A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2022A, len:67. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.005 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	381655	382677	.	-	0	Locus=ML0299c;Name=thiO;Function=;Product=Possible thiamine biosynthesis oxidoreductase ThiO;Comments=ML0299c, len: 340 aa. Possible thiO, thiamine biosynthesis oxidoreductase (EC 1.-.-.-), highly similar to Rv0415|P96261|AL123456 possible thiO, thiamine biosynthesis oxidoreductase from M. tuberculosis (340 aa), Fasta scores: E(): 0, (82.0% identity in 338 aa overlap). Shows weak similarity to GLOX_BACSU|O31616 goxB, glycine oxidase from Bacillus subtilis (369 aa), Fasta scores: E(): 6.6e-10, (28.7% identity in 352 aa overlap). Previously sequenced as Q9ZBL4|AL035159 (340 aa), Fasta scores: E(): 0, (100.0% identity in 340 aa overlap). Also shows weak similarity to ML2011 from M. leprae. Contains Pfam match to entry PF01266 DAO, D-amino acid oxidase.;UniProt_AC=Q9ZBL4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	400772	401779	.	-	0	Locus=ML0314c;Name=lipU;Function=;Product=Possible lipase LipU;Comments=ML0314c, len: 335 aa. Possible lipU, lipase (EC 3.1.-.-), highly similar to Rv1076|O53424|AL123456 lipU, possible lipase from M. tuberculosis (297 aa), Fasta scores: E(): 0, (79.7% identity in 296 aa overlap); and to other putative lipases and esterases from M. tuberculosis. Also similar to other bacterial lipases and esterases e.g. BAH_STRHY|Q01109 bah, acetyl-hydrolase from Streptomyces hygroscopicus (299 aa), Fasta scores: E(): 6.6e-19, (36.2% identity in 246 aa overlap). Previuosly sequenced as Q9ZBM4|AL035159 (335 aa), Fasta scores: E(): 0, (99.7% identity in 335 aa overlap). Contains PS01174 Lipolytic enzymes 'G-D-X-G' family, putative serine active site.;UniProt_AC=Q9ZBM4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	403699	404613	.	-	0	Locus=ML0315c;Name=ML0315c;Function=;Product=Probable oxidoreductase;Comments=ML0315c, len: 304 aa. Probable oxidoreductase (EC 1.-.-.-), highly similar to Rv0068|O53613|AL123456 probable oxidoreductase from M. tuberculosis (303 aa), Fasta scores: E(): 0, (73.9% identity in 306 aa overlap); and to other M. tuberculosis putative oxidoreductases e.g. Rv0439c (311 aa). Similar to many bacterial putative oxidoreductases e.g. CAB69779|AL137187 putative oxidoreductase SC7A8.30C from Streptomyces coelicolor (310 aa), Fasta scores: E(): 0, (47.9% identity in 311 aa overlap). Previously sequenced as Q9ZBM5|AL035159 (304 aa), Fasta scores: E(): 0, (100.0% identity in 304 aa overlap). Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Belongs to the short-chain dehydrogenases/reductases (SDR) family.;UniProt_AC=Q9ZBM5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	404708	405310	.	+	0	Locus=ML0316;Name=ML0316;Function=;Product=Possible transcriptional regulator (TetR family);Comments=ML0316, len: 200 aa. Possible TetR/AcrR-family transcriptional regulator, highly similar except in N-terminus to Rv0067c|O53612|AL123456 possible transcriptional regulator from M. tuberculosis (189 aa), Fasta scores: E(): 0, (68.8% identity in 189 aa overlap). Similar to many putative transcriptional regulators e.g. Q9RJL5|AL121849 putative tetR family transcriptional regulator SCF6.16 from Streptomyces coelicolor (194 aa), Fasta scores: E(): 2.5e-18, (39.5% identity in 185 aa overlap). Previously sequenced as Q9ZBM6|AL035159 (189 aa), Fasta scores: E(): 0, (100.0% identity in 189 aa overlap). Contains a probable helix-turn-helix motif at aa 45-66 (Score 1800, SD +5.32). Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family. Belongs to the tetR/acrR family of transcriptional regulators.;UniProt_AC=Q9CCW8;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	413628	414464	.	+	0	Locus=ML0324;Name=ML0324;Function=;Product=Possible tRNA/rRNA methyltransferase;Comments=ML0324, len: 278 aa. Possible tRNA/rRNA methyltransferase (EC 2.1.1.-), highly similar (longer 31 aa) to Rv3579c|P96861|AL123456 possible tRNA/rRNA methyltransferase from M. tuberculosis (322 aa), Fasta scores: E(): 0, (84.1% identity in 277 aa overlap). Similar to many hypothetical rRNA methyltransferases e.g. Q9L0Q5 putative tRNA/rRNA methyltransferase from Streptomyces coelicolor A3(2) (314 aa), Fasta scores: E(): 0, (54.5% identity in 288 aa overlap). Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family.;UniProt_AC=Q9CCW4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	438263	439315	.	+	0	Locus=ML0348;Name=ML0348;Function=;Product=Possible coenzyme F420-dependent oxidoreductase;Comments=ML0348, len: 350 aa. Possible coenzyme F420-dependent oxidoreductase (EC 1.-.-.-), highly similar to Rv3520c|O53565|AL123456 possible coenzyme F420-dependent oxidoreductase from M. tuberculosis (347 aa), Fasta scores: E(): 0, (86.8% identity in 342 aa overlap). Similar to other coenzyme F420-dependent enzymes (and other proteins) e.g. Q50744|X86477 mer, methylenetetrahydromethanopterin reductase from Methanobacterium thermoautotrophicum  (321 aa), Fasta scores: E(): 2.8e-05, (27.1% identity in 332 aa overlap); and Q9AD98|SCI52.11c putative ATP/GTP-binding protein from Streptomyces coelicolor (351 aa).;UniProt_AC=Q9CCV8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	476441	477286	.	+	0	Locus=ML0383;Name=ML0383;Function=;Product=Conserved hypothetical protein;Comments=ML0383, len: 281 aa. Conserved hypothetical protein, highly similar to Rv3415c|Q50711|AL123456 conserved hypothetical protein from M. tuberculosis (275 aa), Fasta scores: E(): 0, (73.6% identity in 277 aa overlap). Previously sequenced as Q49858|U00020 (264 aa), Fasta scores: E(): 0, (99.6% identity in 263 aa overlap).;UniProt_AC=Q9CCV3;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	486264	488642	.	-	0	Locus=ML0392c;Name=ML0392c;Function=;Product=Possible hydrolase;Comments=ML0392c, len: 792 aa. Possible hydrolase (EC 3.-.-.-), highly similar to Rv3401|YY01_MYCTU|Q50724 conserved hypothetical protein from M. tuberculosis (786 aa), Fasta scores: E(): 0, (91.4% identity in 782 aa overlap). Similar to other bacterial hydrolases and transferases e.g. Q9L2I8|SCF42.31c  putative glycosyl transferase from Streptomyces coelicolor (792 aa), Fasta scores: E(): 0, (58.9% identity in 790 aa overlap); and Q9K109|NMB0390 maltose phosphorylase from Neisseria meningitidis (serogroup B) (752 aa). Previously sequenced as YY01_MYCLE|Q49736 (792 aa), Fasta scores: E(): 0, (100.0% identity in 792 aa overlap). Contains a probable helix-turn-helix motif at aa 515-536 (Score 1032, SD +2.70). Contains Pfam match entry to PF03632; Glyco_hydro_65m, PF03633; Glyco_hydro_65c and PF03636; Glyco_hydro_65n. Belongs to family 65 of glycosyl hydrolases.;UniProt_AC=Q49736;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	564584	565228	.	+	0	Locus=ML0467;Name=dedA;Function=;Product=Possible transmembrane protein DedA;Comments=ML0467, len: 214 aa. Possible dedA, transmembrane protein, highly similar to Rv2637|YQ37_MYCTU|P71936 dedA, dedA-family protein from M. tuberculosis (218 aa), Fasta scores: E(): 0, (82.8% identity in 209 aa overlap). Similar to many dedA-family hypothetical proteins e.g. P09548|DEDA_ECOLI|B2317|Z3579|ECS3201 dedA protein (DSG-1 PROTEIN) from Escherichia coli strains K12 and O157:H7 (219 aa). Previously sequenced as YQ37_MYCLE|Q49642 (214 aa), Fasta scores: E(): 0, (100.0% identity in 214 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF00597 DedA, DedA family. Belongs to the dedA family.;UniProt_AC=Q49642;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	488656	489441	.	-	0	Locus=ML0393c;Name=ML0393c;Function=;Product=Probable hydrolase;Comments=ML0393c, len: 261 aa. Probable hydrolase (EC 3.-.-.-), highly similar to Rv3400|YY00_MYCTU|Q50725 probable hydrolase from M. tuberculosis (262 aa), Fasta scores: E(): 0, (74.4% identity in 262 aa overlap). Similar to several various proteins (notably hydrolases) e.g. Q9L2I7|SCF42.32 PUTATIVE HYDROLASE from Streptomyces coelicolor (246 aa), FASTA scores: opt: 843, E(): 7.6e-47, (51.61% identity in 248 aa overlap); and Q9I5X4|PA0562 PROBABLE HYDROLASE from Pseudomonas aeruginosa (224 aa). Previously sequenced as YY00_MYCLE|Q49741 (261 aa), Fasta scores: E(): 0, (100.0% identity in 261 aa overlap). Contains Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase.;UniProt_AC=Q49741;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	518415	518891	.	-	0	Locus=ML0419c;Name=spoU;Function=;Product=Probable tRNA/rRNA methylase SpoU (tRNA/rRNA methyltransferase);Comments=ML0419c, len: 158 aa. Probable spoU, tRNA/rRNA methylase (EC 2.1.1.-), highly similar to Rv3366|O50394|AL123456 spoU, possible RNA methyltransferase from M. tuberculosis (154 aa), Fasta scores: E(): 0, (83.8% identity in 154 aa overlap). Also similar to many members of the spoU family of rRNA methylases e.g. TRMH_ECOLI|P19396 spoU, tRNA (guanosine-2'-o-)-methyltransferase from Escherichia coli (229 aa), Fasta scores: E(): 4e-05, (30.4% identity in 148 aa overlap); and Q9K199|NMB0268 RNA methyltransferase (TRMH family) from Neisseria meningitidis (serogroup B) (154 aa). Previously sequenced as O07698|Z97179 (169 aa), Fasta scores: E(): 0, (100.0% identity in 158 aa overlap). Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family. Belongs to the RNA methyltransferase TRMH family.;UniProt_AC=Q9CCU7;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	524417	524644	.	+	0	Locus=ML0425;Name=ML0425;Function=;Product=Possible conserved membrane protein;Comments=ML0425, len: 75 aa. Possible conserved membrane protein, similar to Rv2520c|O53225|AL123456 possible conserved membrane protein from M. tuberculosis (75 aa), Fasta scores: E(): 2.2e-15, (57.3% identity in 75 aa overlap). Previously sequenced as O07706|Z97179) (91 aa), Fasta scores: E(): 7.9e-29, (100.0% identity in 75 aa overlap). Contains hydrophobic, possible membrane-spanning region.;UniProt_AC=Q9CCU6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	526295	526942	.	-	0	Locus=ML0427c;Name=orn;Function=;Product=Probable oligoribonuclease Orn ;Comments=ML0427c, len: 215 aa. Probable orn, oligoribonuclease (EC 3.1.-.-), highly similar to Rv2511|ORN_MYCTU|O06174 orn, probable oligoribonuclease from M. tuberculosis (215 aa), Fasta scores: E(): 0, (84.5% identity in 213 aa overlap). Similar to many others e.g. ORN_ECOLI|P39287 orn, oligoribonuclease from Escherichia coli (180 aa), Fasta scores: E(): 8.2e-25, (45.3% identity in 172 aa overlap). Previously sequenced as ORN_MYCLE|O07708 (215 aa), Fasta scores: E(): 0, (99.5% identity in 215 aa overlap).;UniProt_AC=O07708;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	530917	531696	.	-	0	Locus=ML0431c;Name=ML0431c;Function=;Product=Possible conserved proline rich membrane protein;Comments=ML0431c, len: 259 aa. Possible conserved pro-rich membrane protein, highly Similar to Rv2507|O06170|AL123456 membrane protein from M. tuberculosis (273 aa), Fasta scores: E(): 0, (60.4% identity in 275 aa overlap). Previously sequenced as O07711|Z97179 (261 aa), Fasta scores: E(): 0, (100.0% identity in 259 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CCU3;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	566058	566840	.	-	0	Locus=ML0468c;Name=ML0468c;Function=;Product=Possible conserved intergal membrane protein;Comments=ML0468c, len: 260 aa. Possible conserved intergal membrane protein, similar to other bacterial membrane and hypothetical protein e.g. Q9ADJ7|SCBAC14E8.02C putative integral membrane protein from Streptomyces coelicolor (255 aa), Fasta scores: E(): 1.4e-35, (49.2% identity in 255 aa overlap); and Q9YFR6|AP000058|APE0183 hypothetical protein from Aeropyrum pernix (270 aa), Fasta scores: E(): 7.2e-07, (26.2% identity in 256 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q49657;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	593295	594962	.	+	0	Locus=ML0489;Name=ML0489;Function=;Product=Possible conserved lipoprotein;Comments=ML0489, len: 555 aa. Possible conserved lipoprotein precursor, possibly attached to the membrane by a lipid anchor and substrate-binding protein involved in transport, highly similar to YP85_MYCTU|Q50636|Rv2585c Possible conserved lipoprotein precursor from M. tuberculosis (557 aa), Fasta scores: E(): 4.7e-164, (78.9% identity in 546 aa overlap); and CAD94801|Mb2616c from M. bovis (557 aa). Also similar in part to various proteins, principally substrate-binding proteins, e.g. O87329|DCIAE DIPEPTIDE-BINDING PROTEIN from Corynebacterium glutamicum (Brevibacterium flavum) (502 aa), FASTA scores: E(): 4.4e-26, (29.224% identity  in 438 aa overlap); Q8U840 ABC transporter, substrate binding protein from Agrobacterium tumefaciens (strain C58/ATCC 33970) (553 aa), fasta scores: E(): 2.5e-05, (24.726% identity  in 457 aa overlap). Previously sequenced as YP85_MYCLE|Q49646 (426 aa), Fasta scores: E(): 0, (98.8% identity in 332 aa overlap). Contains a probable N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q49646;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	617502	618443	.	+	0	Locus=ML0508;Name=ML0508;Function=;Product=Conserved hypothetical protein;Comments=ML0508, len: 313 aa. Conserved hypothetical protein, highly similar to YP69_MYCTU|Q50652|Rv2569c conserved hypothetical protein from M. tuberculosis (314 aa), Fasta scores: E(): 0, (84.4% identity in 301 aa overlap); and CAD94784|Mb2599c from M. bovis (314 aa). And similar to other hypothetical proteins e.g. Q9HUN8|PA4926 from Pseudomonas aeruginosa (311 aa), FASTA scores: E(): 1.3e-35, (36.774% identity in 310 aa overlap). Also similar to ML0607 and Rv2409c from M. tuberculosis. Contains Pfam match to entry PF01841 Transglut_core, Transglutaminase-like superfamily.;UniProt_AC=Q9CCT2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	599081	599737	.	+	0	Locus=ML0493;Name=ML0493;Function=;Product=Possible glyoxalase II (Hydroxyacylglutathione hydrolase) (GLX II);Comments=ML0493, len: 218 aa. Possible glyoxalase II (EC 3.1.2.6), highly similar to YP81_MYCTU|Q50640|Rv2581c Possible glyoxalase II from M. tuberculosis (224 aa), Fasta scores: E(): 1.1e-82, (82.0% identity in 222 aa overlap); and CAD94797|Mb2612c from M. bovis (224 aa). Also similar to Q9KXP1|SC9C5.33c Possible hydrolase from Streptomyces coelicolor (235 aa), FASTA scores: E(): 5.4e-38, (47.945% identity in 219 aa overlap); and AAP11173 Hydroxyacylglutathione hydrolase from Bacillus cereus (strain ATCC 14579 / DSM 31) (209 aa), fasta scores: E(): 4.3e-25, (39.048% identity in 210 aa overlap). Also similar to ML1391 and ML1912. Previously sequenced as YP81_MYCLE|Q49649 (218 aa), Fasta scores: E(): 0, (99.5% identity in 218 aa overlap). Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily. Belongs to the glyoxalase II family. Cofactor: Binds two Zinc ions.;UniProt_AC=Q49649;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	629569	630654	.	+	0	Locus=ML0518;Name=aroB;Function=;Product=3-dehydroquinate synthase AroB;Comments=ML0518, len: 361 aa. aroB, 3-dehydroquinate synthase (EC 4.6.1.3), highly similar to AROB_MYCTU|P36919|Rv2538c aroB, 3-dehydroquinate synthase from M. tuberculosis   (362 aa), Fasta scores: E(): 0, (87.3% identity in 361 aa overlap); and CAD94752|Mb2567c from M. bovis (362 aa). Also highly similar to many e.g. Q9KXQ6|AROB_STRCO from Streptomyces coelicolor (363 aa), FASTA scores: E(): 2.1e-77, (58.146% identity in 356 aa overlap). Contains Pfam match to entry PF01761 DHQ_synthase, 3-dehydroquinate synthase.;UniProt_AC=Q9CCS4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	628973	629572	.	+	0	Locus=ML0517;Name=aroK;Function=;Product=Shikimate kinase AroK (SK);Comments=ML0517, len: 199 aa. aroK, shikimate kinase (EC 2.7.1.71), highly similar to AROK_MYCTU|P95014|Rv2539c aroK, shikimate kinase from M. tuberculosis (176 aa), Fasta scores: E(): 0, (79.6% identity in 167 aa overlap); and CAD94753|Mb2568c from M. bovis (176 aa). Similar to many e.g. AROK_ECOLI|P24167 aroK, shikimate kinase I from Escherichia coli (172 aa), Fasta scores: E(): 3.5e-13, (38.0% identity in 166 aa overlap). Contains Pfam match to entry PF01202 SKI, Shikimate kinase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS01128 Shikimate kinase signature. Belongs to the Shikimate kinase family.;UniProt_AC=Q9CCS5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	625434	626699	.	+	0	Locus=ML0514;Name=ML0514;Function=;Product=Probable conserved membrane protein;Comments=ML0514, len: 421 aa. Probable conserved membrane protein, highly similar to P95000|AL123456|Rv2553c Conserved membrane protein from M. tuberculosis (417 aa), Fasta scores: E(): 1.1e-123, (72.7% identity in 414 aa overlap); and CAD94768|Mb2583c from M. bovis (417 aa). C-terminal half is similar to e.g. Q9L9G6|AF170880 novB, gene from novobiocin biosynthetic gene cluster from Streptomyces sphaeroides (284 aa), Fasta scores: E(): 2.5e-22, (40.0% identity in 210 aa overlap). Shows full-length similarity to other hypothetical proteins e.g. Q9EWY3|2SCG38.36 CONSERVED HYPOTHETICAL PROTEIN from Streptomyces coelicolor (253 aa), FASTA scores: E(): 1.1e-20, (38.835% identity in 206 aa overlap). Contains hydrophobic, possible membrane-spanning region near the N-terminus.;UniProt_AC=Q9CCS8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	632968	633531	.	+	0	Locus=ML0522;Name=efp;Function=INVOLVED IN PEPTIDE BOND SYNTHESIS. STIMULATE EFFICIENT TRANSLATION AND PEPTIDE-BOND SYNTHESIS ON NATIVE OR RECONSTITUTED 70S RIBOSOMES IN VITRO. PROBABLY FUNCTIONS INDIRECTLY BY ALTERING THE AFFINITY OF THE RIBOSOME FOR AMINOACYL-TRNA, THUS INCREASING THEIR REACTIVITY AS ACCEPTORS FOR PEPTIDYL TRANSFERASE.;Product=Probable elongation factor P Efp;Comments=ML0522, len: 187 aa. Probable efp, elongation factor P, highly similar to EFP_MYCTU|P95019|Rv2534c efp, elongation factor P from M. tuberculosis (187 aa), Fasta scores: E(): 2.8e-76, (94.1% identity in 186 aa overlap); and CAD94748|Mb2563c from M. bovis (187 aa). Similar to many e.g. Q45288|EFP_CORGL from Corynebacterium glutamicum (Brevibacterium flavum) (187 aa), FASTA scores: E(): 6.3e-55, (69.892% identity in 186 aa overlap). Contains Pfam match to entry PF01132 EFP, Elongation factor P (EF-P). Contains PS01275 Elongation factor P signature. Belongs to the elongation factor P family.;UniProt_AC=Q9CCS0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	646544	647836	.	+	0	Locus=ML0533;Name=pyrC;Function=;Product=Probable dihydroorotase PyrC (DHOase);Comments=ML0533, len: 430 aa. Probable pyrC, dihydroorotase (EC 3.5.2.3), highly similar to P71809|AL123456|Rv1381 probable pyrC, dihydroorotase from M. tuberculosis (430 aa), Fasta scores: E(): 0, (88.8% identity in 427 aa overlap); and CAD94277|Mb1416 from M. bovis (430 aa). Similar to many e.g. PYRC_BACCL|P46538 pyrC, dihydroorotase from Bacillus caldolyticus (427 aa), Fasta scores: E(): 4.1e-52, (40.0% identity in 407 aa overlap). Contains Pfam match to entry PF00744 Dihydrooratase, Dihydroorotase-like. Belongs to the DHOase family. Subfamily 2. Cofactor: Binds 2 zinc ion per subunit.;UniProt_AC=Q9CCR4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	817110	818258	.	-	0	Locus=ML0682c;Name=metA;Function=;Product=Probable homoserine o-acetyltransferase MetA;Comments=ML0682c, len: 382 aa. Probable metA, homoserine o-acetyltransferase (EC 2.3.1.31), highly similar to O53391|AL123456|Rv3341 metA, homoserine o-acetyltransferase from M. tuberculosis (379 aa), Fasta scores: E(): 0, (85.0% identity in 380 aa overlap); and CAD95499|Mb3373 from M. bovis (379 aa). Similar to many e.g. Q8FRT0|METX_COREF Homoserine O-acetyltransferase from Corynebacterium efficiens (388 aa), fasta scores: E(): 2.9e-65, (49.086% identity in 383 aa overlap). Previously sequenced as O32874|Z98271 (382 aa), Fasta scores: E(): 0, (100.0% identity in 382 aa overlap). Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. BELONGS TO THE AB HYDROLASE FAMILY, HTA SUBFAMILY.;UniProt_AC=O32874;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	697159	697944	.	+	0	Locus=ML0572;Name=tpi;Function=;Product=Probable triosephosphate isomerase Tpi (TIM);Comments=ML0572, len: 261 aa. Probable tpi, Triosephosphate isomerase (EC 5.3.1.1), highly similar to TPIS_MYCTU|O08408|Rv1438 tpi, triosephosphate isomerase from M. tuberculosis (261 aa), Fasta scores: E(): 0, (83.9% identity in 261 aa overlap). Similar to many e.g. TPIS_CORGL|P19583 tpi, triosephosphate isomerase from Corynebacterium glutamicum (259 aa), Fasta scores: E(): 0, (64.5% identity in 256 aa overlap). Previously sequenced as TPIS_MYCLE|P46711 (261 aa), Fasta scores: E(): 0, (99.6% identity in 261 aa overlap). Contains Pfam match to entry PF00121 TIM, Triosephosphate isomerase. Contains PS00171 Triosephosphate isomerase active site. Belongs to the Triosephosphate isomerase family.;UniProt_AC=P46711;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	738235	739212	.	+	0	Locus=ML0606;Name=ML0606;Function=;Product=Conserved hypothetical protein;Comments=ML0606, len: 325 aa. Conserved hypothetical protein, highly similar to P71733|AL123456|Rv2410c conserved hypothetical protein from M. tuberculosis (325 aa), Fasta scores: E(): 0, (90.8% identity in 325 aa overlap); and CAD97294|Mb2433c from M. bovis (325 aa). Similar to other bacterial hypothetical proteins. This CDS and the upstream CDS are also similar to the C- and N-terminal regions respectively, of the longer hypothetical proteins from M. tuberculosis and M. leprae e.g. Rv2567|YP67_MYCTU from M. tuberculosis (884 aa); and ML2679 from M. leprae (894 aa). Previously sequenced as Q49770|U00016 (325 aa), Fasta scores: E(): 0, (100.0% identity in 325 aa overlap).;UniProt_AC=Q49770;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	703243	703986	.	-	0	Locus=ML0579c;Name=devB;Function=;Product=Probable 6-phosphogluconolactonase DevB (6PGL);Comments=ML0579c, len: 247 aa. Possible devB (pgl), 6-phosphogluconolactonase (EC 3.1.1.31), highly similar to 6PGL_MYCTU|O06814|Rv1445c devB, 6-phosphogluconolactonase from M. tuberculosis (247 aa), Fasta scores: E(): 0, (72.8% identity in 246 aa overlap); and CAD96147|Mb1480c from M. bovis (247 aa). Similar to many e.g. Q9XAB7|6PGL_STRCO 6-phosphogluconolactonase from Streptomyces coelicolor (261 aa), fasta scores: E(): 5.5e-45, (51.639% identity in 244 aa overlap). Previously sequenced as 6PGL_MYCLE|Q49700 (247 aa), Fasta scores: E(): 0, (99.6% identity in 247 aa overlap). Contains Pfam match to entry PF01182 Glucosamine_iso, Glucosamine-6-phosphate isomerase. Belongs to the Glucosamine/Galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.;UniProt_AC=Q49700;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	706462	707589	.	-	0	Locus=ML0582c;Name=tal;Function=;Product=Probable transaldolase Tal;Comments=ML0582c, len: 375 aa. Probable tal, Transaldolase (EC 2.2.1.2), highly similar to TAL_MYCTU|O06812|Rv1448c tal, transaldolase from M. tuberculosis (373 aa), Fasta scores: E(): 7.9e-120, (78.9% identity in 370 aa overlap); and CAD96150|Mb1483c from M. bovis (373 aa). Highly similar to many e.g. O88018|TAL1_STRCO Transaldolase 1 from Streptomyces coelicolor (381 aa), fasta scores: E(): 2e-85, (61.983% identity in 363 aa overlap). Previously sequenced as TAL_MYCLE|P55193 (375 aa), Fasta scores: E(): 0, (100.0% identity in 375 aa overlap). Contains Pfam match to entry PF00923 Transaldolase, Transaldolase. Contains PS01054 Transaldolase signature 1. Contains PS00958 Transaldolase active site. Belongs to the Transaldolase family.;UniProt_AC=P55193;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	717873	718637	.	+	0	Locus=ML0592;Name=ML0592;Function=;Product=Probable transcriptional regulatory protein;Comments=ML0592, len: 254 aa. Probable transcriptional regulatory protein, highly similar to O53151|AL123456|Rv1460 Probable transcriptional regulatory protein from M. tuberculosis (268 aa), Fasta scores: E(): 0, (79.6% identity in 250 aa overlap); and CAD96162|Mb1495 from M. bovis (268 aa). Similar to other bacterial transcriptional regulatory and hypothetical proteins e.g. Q8NQ74 Predicted transcriptional regulator from Corynebacterium glutamicum (Brevibacterium flavum) (231 aa), fasta scores:  E(): 2.3e-36, (49.302% identity in 215 aa overlap); and Q9XAD0|AL096839|SCC22.08C putative DNA-binding protein from Streptomyces coelicolor (252 aa), Fasta scores: E(): 5.6e-30, (45.4% identity in 216 aa overlap). Previously sequenced as Q49688|U00013 (254 aa), Fasta scores: E(): 0, (99.6% identity in 254 aa overlap). Contains a probable helix-turn-helix motif at aa 215-236 (Score 1054, SD +2.78);UniProt_AC=Q49688;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	724980	725327	.	+	0	Locus=ML0598;Name=ML0598;Function=;Product=Conserved hypothetical protein;Comments=ML0598, len: 115 aa. Conserved hypothetical protein, highly similar to O53157|AL123456|Rv1466 conserved hypothetical protein from M. tuberculosis (115 aa), Fasta scores: E(): 0, (82.6% identity in 115 aa overlap); and CAD96168|Mb1501 from M. bovis (656 aa). Similar to several hypothetical proteins and hypothetical proteins located downstream of sigma factors in Streptococcus mutans and Streptococcus pneumoniae e.g. O06451 ORF3 downstream of RpoD (SPDNAGCPO) (109 aa). Previously sequenced as Q49691|U00013 (115 aa), Fasta scores: E(): 0, (100.0% identity in 115 aa overlap). Contains Pfam match to entry PF01883 DUF59, Domain of unknown function.;UniProt_AC=Q49691;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	756771	757802	.	+	0	Locus=ML0624;Name=hrcA;Function=;Product=Probable heat-inducible transcription repressor HrcA;Comments=ML0624, len: 343 aa. Probable hrcA, heat-inducible transcriptional repressor (see citation below), highly similar to HRCA_MYCTU|O05824|Rv2374c hrcA, heat-inducible transcription repressor from M. tuberculosis (343 aa), Fasta scores: E(): 1.2e-116, (89.5% identity in 343 aa overlap); and CAD97256|Mb2395c from M. bovis (343 aa). Similar to many e.g. HRCA_BACST|Q45550 hcrA, heat-inducible transcription repressor from Bacillus stearothermophilus (344 aa), Fasta scores: E(): 3.5e-26, (28.3% identity in 336 aa overlap). Previously sequenced as Q49749|U00016 (197 aa), Fasta scores: E(): 0, (99.5% identity in 196 aa overlap). Contains Pfam match to entry PF01628 HrcA, HrcA protein. Belongs to the HrcA family.;UniProt_AC=Q9CCN2;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	761195	761731	.	+	0	Locus=ML0628;Name=ML0628;Function=;Product=Conserved hypothetical protein;Comments=ML0628, len: 178 aa. Conserved hypothetical protein, highly similar to YN67_MYCTU|O05831|Rv2367c Conserved hypothetical protein from M. tuberculosis (182 aa), Fasta scores: E(): 5.9e-67, (89.1% identity in 175 aa overlap); and CAD97249|Mb2388c from M. bovis (182 aa). Similar to many bacterial hypothetical proteins e.g. Q9L2L4|YP33_STRCO|AL136534|SCC117.06 hypothetical protein from Streptomyces coelicolor (165 aa), Fasta scores: E(): 1e-31, (54.5% identity in 154 aa overlap). Similar to O51806|AF000954 dgk, diacyglycerol kinase from Streptococcus mutans (164 aa), Fasta scores: E(): 3.8e-07, (30.9% identity in 162 aa overlap). Previously sequenced as YN67_MYCLE|Q49752 (178 aa), Fasta scores: E(): 0, (100.0% identity in 178 aa overlap). Contains Pfam match to entry PF02130 UPF0054, Uncharacterized protein family UPF0054. Contains PS01306 Uncharacterized protein family UPF0054 signature.;UniProt_AC=Q49752;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	380273	380475	.	-	0	Locus=ML0296A;Name=ML0296A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0296A, len:202. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-14 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	763033	763359	.	+	0	Locus=ML0630;Name=ML0630;Function=;Product=Conserved hypothetical protein;Comments=ML0630, len: 108 aa. Conserved hypothetical protein, highly similar to O05833|AL123456|Rv2365c Conserved hypothetical protein from M. tuberculosis (113 aa), Fasta scores: E(): 1.5e-22, (67.9% identity in 106 aa overlap); and CAD97247|Mb2386c (113 aa) from M. bovis. Similar to Q9RDF3|AL136503|SCC77.05 Hypothetical protein from Streptomyces coelicolor (132 aa), Fasta scores: E(): 3.3e-06, (39.4% identity in 99 aa overlap). Previously sequenced as Q49767|U00016 (108 aa), Fasta scores: E(): 0, (100.0% identity in 108 aa overlap).;UniProt_AC=Q49767;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	774507	775946	.	-	0	Locus=ML0642c;Name=ML0642c;Function=;Product=Conserved hypothetical protein;Comments=ML0642c, len: 479 aa. Conserved hypothetical protein, highly similar to O53341|AL123456|Rv3195 conserved hypothetical protein from M. tuberculosis (472 aa), Fasta scores: E(): 0, (79.2% identity in 475 aa overlap) and CAD95309|Mb3217 from M. bovis (472 aa). Similar to several hypothetical proteins e.g. Q9FCI9|SCO5199 Hypothetical protein from Streptomyces coelicolor (487 aa), Fasta scores: opt: 1341, E(): 3e-76, (44.856% identity in 486 aa overlap). Previously sequenced as Q49746|U00016 (479 aa), Fasta scores: E(): 0, (99.8% identity in 479 aa overlap).;UniProt_AC=Q49746;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	776009	777031	.	+	0	Locus=ML0643;Name=ML0643;Function=;Product=Possible conserved secreted protein;Comments=ML0643, len: 340 aa. Possible conserved secreted protein, highly similar to O53340|AL123456|Rv3194c conserved hypothetical protein from M. tuberculosis (340 aa), Fasta scores: E(): 0, (80.3% identity in 340 aa overlap); and CAD95308|Mb3216c from M. bovis (340 aa). Similar to other bacterial hypothetical and putative secreted protein e.g. Q8NS96 Predicted secreted protein containing a PDZ domain from Corynebacterium glutamicum (Brevibacterium flavum) (350 aa), fasta scores: opt: 912, E(): 9.5e-49, (42.571% identity in 350 aa overlap); and Q9S3Y5|AF170560 sdrC, hypothetical protein from Streptomyces coelicolor (241 aa), Fasta scores: E(): 5.5e-18, (34.9% identity in 318 aa overlap). Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CCM7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	771723	771992	.	+	0	Locus=ML0639;Name=whiB7;Function=;Product=Probable transcriptional regulatory protein WhiB7;Comments=ML0639, len: 89 aa. Probable whiB7, WhiB-like regulatory protein, highly similar to Rv3197A whiB7, WhiB-like regulatory protein from M. tuberculosis (92 aa), fasta scores: opt: 441, E(): 1.5e-26, (69.318% identity in 88 aa overlap); and CAD95313|Mb3221c from M. bovis (92 aa). Shows similarity to members of the whiB-family of transcriptional regulators e.g. Q8GHG1 WhiB7 from Streptomyces coelicolor A3(2) (122 aa), fasta scores: opt: 316, E(): 9.6e-17, (56.522% identity in 69 aa overlap). Also similar to ML0382, ML0760, ML0804 and ML2307 from M. leprae. Previously sequenced as Q49765|U00016 (89 aa), Fasta scores: E(): 0, (100.0% identity in 89 aa overlap). Contains a match to Pfam entry PF02467; Whib.;UniProt_AC=Q49765;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1061011	1061526	.	+	0	Locus=ML0895;Name=ML0895;Function=;Product=conserved hypothetical protein;Comments=ML0895, len: 171 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69570 (EMBL:AL022602) (171 aa), Fasta scores: E(): 0, 100.0% identity in 171 aa overlap and highly similar to Mycobacterium tuberculosis hypothetical protein TR:O53513 (EMBL:AL021957) (168 aa), Fasta scores: E(): 0, 83.1% identity in 166 aa overlap.;UniProt_AC=O69570;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	797293	798690	.	-	0	Locus=ML0661c;Name=fadE24;Function=;Product=Probable acyl-CoA dehydrogenase FadE24;Comments=ML0661c, len: 465 aa. Probable fadE24, acyl-CoA dehydrogenase (1.3.99.-), highly similar to P95187|AL123456|Rv3139 fadE24, acyl-CoA dehydrogenase from M. tuberculosis (468 aa), Fasta scores: E(): 2e-163, (83.6% identity in 464 aa overlap); and CAD95255|Mb3163 from M. bovis (468 aa). Similar to many e.g. Q9HUH0 Probable acyl-CoA dehydrogenase from Pseudomonas aeruginosa (429 aa), fasta scores:  opt: 1116, E(): 5.2e-66, (44.836% identity  in 426 aa overlap). Also similar to ML0737. Previously sequenced as O32890|Z98271 (465 aa), Fasta scores: E(): 0, (100.0% identity in 465 aa overlap) .Contains 2 Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. Contains PS00073 Acyl-CoA dehydrogenases signature 2.;UniProt_AC=O32890;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	805921	806610	.	+	0	Locus=ML0669;Name=ftsE;Function=;Product=Putative cell division ATP-binding protein FtsE (SEPTATION COMPONENT-TRANSPORT  ATP-BINDING PROTEIN ABC TRANSPORTER);Comments=ML0669, len: 229 aa. Putative ftsE, cell division protein, septation component transport ATP-binding protein ABC transporter, highly similar to O05779|AL123456|Rv3102c ftsE, cell division protein, septation component transport ATP-binding protein ABC transporter from M. tuberculosis (229 aa), Fasta scores: E(): 0, (91.7% identity in 229 aa overlap); and CAD96816|Mb3129c from M. bovis (229 aa). Similar to many e.g. FTSE_ECOLI|P10115 ftsE, cell division ATP-binding protein from Escherichia coli (222 aa), Fasta scores: E(): 0, (49.1% identity in 216 aa overlap). Previously sequenced as O32883|Z98271 (229 aa), Fasta scores: E(): 0, (100.0% identity in 229 aa overlap). Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).;UniProt_AC=O32883;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	798767	799534	.	-	0	Locus=ML0662c;Name=ML0662c;Function=;Product=Probable monophosphatase;Comments=ML0662c, len: 255 aa. Probable monophosphatase (EC 3.1.3.-), highly similar to P95189|AL123456|Rv3137 Probable monophosphatase from M. tuberculosis (260 aa), Fasta scores: E(): 0, (81.8% identity in 253 aa overlap); and CAD95253|Mb3161 from M. bovis (260 aa). Similar to several e.g. Q9K4B1 Putative monophosphatase from Streptomyces coelicolor (266 aa), fasta scores:  opt: 955, E(): 3.7e-56, (56.746% identity  in 252 aa overlap). Also similar to ML1024. Previously sequenced as O32889|Z98271 (255 aa), Fasta scores: E(): 0, (100.0% identity in 255 aa overlap). Contains 2 Pfam matches to entry PF00459 inositol_P, Inositol monophosphatase family. Contains PS00629 Inositol monophosphatase family signature 1.;UniProt_AC=O32889;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	807507	807989	.	+	0	Locus=ML0671;Name=smpB;Function=;Product=Probable SsrA-binding protein SmpB;Comments=ML0671, len: 160 aa. Probable smpB, SsrA-binding protein, highly similar to SMPB_MYCTU|P96294|Rv3100c smpB, SsrA-binding protein from M. tuberculosis (160 aa), Fasta scores: E(): 0, (84.9% identity in 159 aa overlap); and CAD96814|Mb3127c from M. bovis (160 aa). Similar to many e.g. SMPB_ECOLI|P32052 smpB, SSRA-binding protein essential for the peptide-tagging activity of SsrA (tmRNA) from  Escherichia coli (159 aa), Fasta scores: E(): 4.1e-19, (41.8% identity in 146 aa overlap). Previously sequenced as SMPB_MYCLE|O32881 (160 aa), Fasta scores: E(): 0, (99.4% identity in 160 aa overlap). Contains Pfam match to entry PF01668 SmpB, SmpB protein. Contains PS01317 Protein smpB signature. BELONGS TO THE SSRP FAMILY.;UniProt_AC=O32881;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	435450	435566	.	-	0	Locus=ML0344A;Name=ML0344A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0344A, len:116. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	840883	842154	.	-	0	Locus=ML0703c;Name=ML0703c;Function=;Product=Conserved hypothetical protein;Comments=ML0703c, len: 423 aa. Conserved hypothetical protein, highly similar to O53362|AL123456|Rv3311 conserved hypothetical protein from M. tuberculosis (420 aa), Fasta scores: E(): 0, (77.5% identity in 423 aa overlap); and CAD95431|Mb3339 from M. bovis (420 aa). Weakly similar to Q8NSJ0 Hypothetical protein Cgl0681 from Corynebacterium glutamicum (Brevibacterium flavum) (409 aa), fasta scores: E(): 3.1e-26, (31.579% identity in 418 aa overlap).;UniProt_AC=Q9CCL8;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	836442	836933	.	-	0	Locus=ML0698c;Name=sdhD;Function=;Product=Probable succinate dehydrogenase (hydrophobic membrane anchor protein) SdhD (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE);Comments=ML0698c, len: 163 aa. Probable sdhD, membrane anchor of succinate dehydrogenase SdhD subunit (EC 1.3.99.1), highly similar to O53369|AL123456|Rv3317 sdhD, putative membrane anchor of succinate dehydrogenase from M. tuberculosis (144 aa), Fasta scores: E(): 0, (85.2% identity in 142 aa overlap); and CAD95438|Mb3346 from M. bovis (144 aa). Similar to several e.g. Q9KZ89 Putative succinate dehydrogenase membrane subunit from Streptomyces coelicolor  (160 aa), fasta scores: E(): 1.6e-29, (50.968% identity in 155 aa overlap). Previously sequenced as Q49915|U00022 (163 aa), Fasta scores: E(): 0, (100.0% identity in 163 aa overlap). Contains hydrophobic, possible membrane-spanning regions. PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC ANCHOR PROTEIN.;UniProt_AC=Q49915;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	871758	872012	.	-	0	Locus=ML0730c;Name=ML0730c;Function=;Product=Conserved hypothetical protein;Comments=ML0730c, len: 84 aa. Conserved hypothetical protein, similar to Rv3281|MTCY71.21|P96886|Z92771 Conserved hypothetical protein from Mycobacterium tuberculosis (177 aa) fasta scores: E(): 2.4e-22, (69.0% identity in 87 aa); and CAD95401|Mb3309 from M. bovis (156 aa). Previously sequenced as Q49671|U00012. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain.;UniProt_AC=Q49671;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	870029	870919	.	-	0	Locus=ML0728c;Name=sseA;Function=;Product=Probable thiosulfate sulfurtransferase SseA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE);Comments=ML0728c, len: 296 aa. Probable sseA, thiosulfate sulfurtransferase (EC 2.8.1.1), highly similar to THT2_MYCTU|P96888|Rv3283 sseA, thiosulfate sulfurtransferase from M. tuberculosis (297 aa), Fasta scores: E(): 5.4e-110, (83.4% identity in 296 aa overlap); and CAD95403|Mb3311 from M. bovis (297 aa). Similar to many e.g. P71121|THTR_CORGL Thiosulfate sulfurtransferase from Corynebacterium glutamicum (Brevibacterium flavum) (301 aa), fasta scores: E(): 1.5e-73, (58.276% identity in 290 aa overlap). Also similar to ML2198 from M. leprae and Rv3117 from M. tuberculosis. Previously sequenced as THT2_MYCLE|P46700 (296 aa), Fasta scores: E(): 0, (99.7% identity in 296 aa overlap).  Contains 2 Pfam matches to entry PF00581 Rhodanese, Rhodanese-like domain. Contains PS00380 Rhodanese signature 1. Contains PS00683 Rhodanese C-terminal signature. BELONGS TO THE RHODANESE FAMILY. In M. tuberculosis sseA is thought to be differentially expressed within host cells (see Triccas et al., 1999).;UniProt_AC=P46700;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	874678	875196	.	+	0	Locus=ML0733;Name=ML0733;Function=;Product=Probable conserved transmembrane protein;Comments=ML0733, len: 172 aa. Probable conserved transmembrane protein, highly similar to Rv3278c|MTCY71.18c|P96883|Z92771 conserved transmembrane protein from Mycobacterium tuberculosis (172 aa), fasta scores: E(): 0, (83.1% identity in 172 aa); and CAD95398| from M. bovis (172 aa). Previously sequenced as Q49672|U00012. Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CCL2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1042386	1043024	.	+	0	Locus=ML0878;Name=ML0878;Function=;Product=Probable conserved transmembrane protein;Comments=ML0878, len: 212 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis transmembrane protein Rv2197c|MTCY190.08C|YL97_MYCTU|Q10389 (214 aa) fasta scores: E(): 0, 62.6% identity in 211 aa and Rv0008c|MTCY10H4.07c|Y008_MYCTU|P71577 from M. tuberculosis (214 aa) fasta scores: E(): 0, 62.6% identity in 211 aa. Contains several membrane spanning regions.;UniProt_AC=Q9CCE8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	875151	875837	.	-	0	Locus=ML0734c;Name=ML0734c;Function=;Product=Probable conserved transmembrane protein;Comments=ML0734c, len: 228 aa. Probable conserved transmembrane protein, highly similar to Rv3277|MTCY71.17|P96882|Z92771 Probable conserved transmembrane protein from Mycobacterium tuberculosis hypothetical (272 aa), fasta scores: E(): 4e-84, (84.6% identity in 228 aa); and CAD95397|Mb3305 from M. bovis (272 aa). Also similar to other membrane proteins e.g. Q82DA6 Putative integral membrane protein from Streptomyces avermitilis (162 aa), fasta scores: E(): 1.2e-08, (35.075% identity in 134 aa overlap). Previously sequenced as Q49673|U00012. Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q49673;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	890982	891260	.	-	0	Locus=ML0748c;Name=ML0748c;Function=;Product=conserved hypothetical protein;Comments=ML0748c, len: 92 aa. Conserved hypothetical protein, highly similar to Rv3269|MTCY71.09|P96874|Z92771 Conserved hypothetical protein from M. tuberculosis (93 aa) fasta scores: E(): 5.5e-23, (73.6% identity in 91 aa), CAD95389| from M. bovis (93 aa). Similar to many Mycobacterium proteins and chaperonins/heat shock proteins e.g. Rv1993c|MTCY39.26|YJ93_MYCTU|Q10865 hypothetical protein from M. tuberculosis (90 aa),  fasta scores: E(): 6.3e-14, (60.8% identity in 79 aa) and Rv0968|MTCY10D7.06c|Y968_MYCTU|P71542 hypothetical protein from M. tuberculosis (98 aa), fasta scores:E(): 4.4e-11, (52.1% identity in 96 aa).;UniProt_AC=Q9CCL0;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	893622	894557	.	+	0	Locus=ML0751;Name=rmlD;Function=;Product=dTDP-6-deoxy-L-lyxo-4-hexulose reductase RmlD (dTDP-RHAMNOSE MODIFICATION PROTEIN) (dTDP-RHAMNOSE BIOSYNTHESIS PROTEIN) (dTDP-RHAMNOSE SYNTHASE);Comments=ML0751, len: 311 aa. Probable rmlD, dTDP-6-deoxy-L-lyxo-4-hexulose reductase (dTDP-rhamnose modification protein) (EC 1.-.-.-) (see citations below), highly similar to Rv3266c|MTCY71.06c|P96871|Z92771 rmlD, dTDP-6-deoxy-L-lyxo-4-hexulose reductase from Mycobacterium tuberculosis (304 aa), fasta scores: E(): 0, (74.4% identity in 312 aa); and CAD95386|Mb3294c from M. bovis (304 aa). Similar to several dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) e.g. P29781|STRL_STRGR dTDP-4-dehydrorhamnose reductase from Streptomyces griseus (304 aa), fasta scores: E(): 1.4e-32, (44.409% identity in 313 aa overlap).;UniProt_AC=Q9CCK8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	936848	937606	.	+	0	Locus=ML0793;Name=ML0793;Function=;Product=conserved hypothetical protein;Comments=ML0793, len: 252 aa. Conserved hypothetical protein, highly similar to Rv3226c|MTCY20B11.01c|O05872|Z95121 Conserved hypothetical protein from M. tuberculosis (252 aa), fasta scores: E(): 7.5e-76, (70.6% identity in 252 aa); and CAD95347| from M. bovis (252 aa). Similar to various hypothetical bacterial proteins e.g. O64131|AF020713  yoqW protein from Bacteriophage SPBc2 (224 aa), fasta scores: E(): 4.8e-21, (36.5% identity in 244 aa).;UniProt_AC=Q9CCI2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	942267	942443	.	+	0	Locus=ML0796;Name=ML0796;Function=;Product=conserved hypothetical protein;Comments=ML0796, len: 58 aa. Conserved hypothetical protein, similar to the N-termini of Rv0844c|MTV043.37c|O53856|AL022004 Possible narL, nitrate/nitrite response regulator protein from Mycobacterium tuberculosis(216 aa), fasta scores: E(): 0.2, (39.7% identity in 63 aa); and Q53894|U51332|SCE8.19 absA2 from Streptomyces coelicolor (222 aa), fasta scores: E(): 4.3, (38.5% identity in 52 aa). This truncated CDS is possibly a pseudogene.;UniProt_AC=Q7AQF5;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	445850	446608	.	+	0	Locus=ML0352A;Name=ML0352A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0352A, len:758. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-27 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	470765	471844	.	+	0	Locus=ML0378;Name=ML0378;Function=;Product=probable acetyltransferase;Comments=ML0378, len: 359 aa. Probable acetyltransferase (EC 2.3.1.-). ML0378 appears to be a fusion of two M. tuberculosis homologues. In the C-terminus it is very similar to Rv3420c|Q50708|Z77165  rimI, probable ribosomal protein S18 acetyltransferase (158 aa), Fasta scores: E(): 0, (72.1% identity in 154 aa overlap); and in the N-terminus to Rv3421c|YY21_MYCTU|Q50707 conserved hypothetical protein (211 aa), Fasta scores: E(): 0, (75.6% identity in 205 aa overlap). Also similar to some other bacterial acetyltransferases and hypothetical proteins. Previously sequenced as YY21_MYCLE|Q49857 (359 aa), Fasta scores: E(): 0, (100.0% identity in 359 aa overlap). Contains Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family. ;UniProt_AC=Q49857;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	622160	624886	.	+	0	Locus=ML0512;Name=alaS;Function=;Product=Probable alanyl-tRNA synthetase AlaS (Alanine--tRNA ligase) (Alanine translase) AlaRS);Comments=ML0512, len: 908 aa. Probable alaS, alanyl-tRNA synthetase (EC 6.1.1.7), highly similar to SYA_MYCTU|O07438|Rv2555c alaS, alanyl-tRNA synthetase from M. tuberculosis (904 aa), Fasta scores: E(): 0, (84.7% identity in 907 aa overlap); and CAD94770|Mb2585c from M. bovis (904 aa). Similar to many e.g. Q9KXP9|SYA_STRCO from Streptomyces coelicolor (890 aa), FASTA scores: E(): 1.5e-117, (52.150% identity in 907 aa overlap). Contains Pfam match to entry PF01411 tRNA-synt_2c, tRNA synthetases class II (A). Contains PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. Belongs to the class-II aminoacyl-tRNA synthetase family.;UniProt_AC=Q9CCT0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	626677	627513	.	+	0	Locus=ML0515;Name=aroE;Function=;Product=Probable shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase);Comments=ML0515, len: 278 aa. Probable aroE, shikimate 5-dehydrogenase (EC 1.1.1.25), highly similar to P95001|AL123456|Rv2552c aroE, shikimate 5-dehydrogenase from M. tuberculosis (269 aa), Fasta scores: E(): 0, (81.5% identity in 270 aa overlap); and CAD94767|Mb2582c from M. bovis (260 aa).  Also highly similar, but longer than Q9KH59 Putative shikimate dehydrogenase (fragment) from Mycobacterium marinum (148 aa), FASTA scores: E(): 5.7e-38, (72.848% identity in 151 aa overlap); and Q9F7W3|AROE_METTH from Mycobacterium ulcerans (148 aa). Similar to many e.g. Q9KXQ2|AROE from Streptomyces coelicolor (255 aa), FASTA scores: E(): 1.7e-27, (41.339% identity in 254 aa overlap). Contains Pfam match to entry PF01488 Shikimate_DH, Shikimate / quinate 5-dehydrogenase. Belongs to the shikimate dehydrogenase family.;UniProt_AC=Q9CCS7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	709905	710870	.	+	0	Locus=ML0584;Name=ctaB;Function=;Product=Probable cytochrome C oxidase assembly factor CtaB;Comments=ML0584, len: 321 aa. Probable cta, cytochrome C oxidase assembly factor  Similar to M. tuberculosis ctaB, Rv1451, cytochrome c oxidase assembly factor, TR:O06809 (EMBL:AL123456) (308 aa), Fasta scores: E(): 0, 82.7% identity in 307 aa overlap. Similar to many e.g. Bacillus firmus ctaB, protoheme IX farnesyltransferase, SW:COXX_BACFI (Q04444) (312 aa), Fasta scores: E(): 7.8e-24, 33.6% identity in 283 aa overlap. Previously sequenced as TR:Q49685 (EMBL:U00013) (300 aa), Fasta scores: E(): 0, 99.7% identity in 300 aa overlap. Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF01040 UbiA, UbiA prenyltransferase family.;UniProt_AC=Q9CCN4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	461562	461892	.	-	0	Locus=ML0369A;Name=ML0369A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0369A, len:330. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-31 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	649609	652998	.	+	0	Locus=ML0536;Name=carB;Function=;Product=Probable carbamoyl-phosphate synthase large subunit CarB (Carbamoyl-phosphate synthetase ammonia chain);Comments=ML0536, len: 1129 aa. Probable carB, Carbamoyl-phosphate synthase large chain (EC 6.3.5.5), highly similar to P57689|CARB_MYCTU|Rv1384 carB, carbamoyl-phosphate synthase subunit from M. tuberculosis (1115 aa), fasta scores: E(): 0, (88.839% identity in 1111 aa overlap) ; and CAD94280|Mb1419 from M. bovis (1115 aa). Highly similar to many e.g. CARB_ECOLI|P00968 carB, carbamoyl-phosphate synthase subunit from Escherichia coli (1072 aa), Fasta scores: (51.4% identity in 1116 aa overlap). Contains 2 Pfam matches to entry PF00289 CPSase_L_chain, Carbamoyl-phosphate synthase (CPSase). Contains 2 x PS00867 Carbamoyl-phosphate synthase subdomain signature 2. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00866 Carbamoyl-phosphate synthase subdomain signature 1. SUBUNIT: COMPOSED OF TWO CHAINS; THE SMALL (OR GLUTAMINE) CHAIN PROMOTES THE HYDROLYSIS OF GLUTAMINE TO AMMONIA, WHICH IS USED BY THE LARGE (OR AMMONIA) CHAIN TO SYNTHESIZE CARBAMOYL PHOSPHATE. Belongs to the CarB family.;UniProt_AC=Q9CCR2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1443568	1443810	.	+	0	Locus=ML1221;Name=ML1221;Function=;Product=Conserved hypothetical protein;Comments=ML1221, len: 80 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49616 (EMBL:U00010) (80 aa), Fasta scores: E(): 0, 98.8% identity in 80 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1590 TR:O06600 (EMBL:Z95586) (79 aa), Fasta scores: E(): 3.4e-21, 67.1% identity in 73 aa overlap.;UniProt_AC=Q49616;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	763477	764385	.	+	0	Locus=ML0631;Name=era;Function=;Product=Probable GTP-binding protein Era;Comments=ML0631, len: 302 aa. Probable era, GTP-binding protein, highly similar to ERA_MYCTU|O05834|Rv2364c era, GTP-binding protein from M. tuberculosis (300 aa), Fasta scores: E(): 5.9e-95, (81.4% identity in 301 aa overlap); and CAD97246|Mb2385c (300 aa) from M. bovis. Similar to many bacterial era-homologues and to ERA_ECOLI|P06616 era, GTP-binding protein from Escherichia coli (301 aa), Fasta scores: E(): 3.3e-30, (34.3% identity in 297 aa overlap). Previously sequenced as ERA_MYCLE|Q49768 (302 aa), Fasta scores: E(): 0, (99.7% identity in 302 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). CONTAINS 1 KH TYPE-2 DOMAIN. BELONGS TO THE ERA/TRME FAMILY OF GTP-BINDING PROTEINS, ERA SUBFAMILY.;UniProt_AC=Q49768;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	584382	587948	.	-	0	Locus=ML0484c;Name=fadD9;Function=;Product=Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase);Comments=ML0484c, len: 1188 aa. Probable fadD9, fatty-acid-CoA synthetase (EC 6.2.1.-), highly similar to Q50631|Al123456|Rv2590 fadD9, probable fatty-acid-CoA synthetase from M. tuberculosis (1168 aa), fasta scores: E(): 0, (68.0% identity in 1178 aa overlap). Similar to other long chain fatty acid ligases and to domains of polyketide/peptide synthetases e.g. Q10896|Rv0101|MTCY251.20|NRP Probable peptide synthetase from Mycobacterium tuberculosis (2512 aa), FASTA scores: E(): 1.8e-116, (41.313% identity in 1036 aa overlap); Q9RLP6|AJ238027 mps, peptide synthetase from Mycobacterium smegmatis (5990 aa), fasta scores: E(): 4.6e-99, (37.2% identity in 1168 aa overlap). Previously sequenced as O69484|AL023591 (1174 aa), Fasta scores: E(): 0, (100.0% identity in 1174 aa overlap). Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature. Contains PS00061 Short-chain dehydrogenases/reductases family signature. Seems to belong to the ATP-dependent AMP-binding enzyme family, and to the short-chain dehydrogenses/reductases (SDR) family.;UniProt_AC=Q9CCT4;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	998975	999898	.	+	0	Locus=ML0841;Name=mmp1;Function=;Product=major membrane protein I Mmp1;Comments=ML0841, len: 307 aa. mmp1, Major membrane protein 1.  Highly similar to Q9RAJ4|AJ250887 Mycobacterium paratuberculosis 35 kDa protein (307 aa), fasta scores: E(): 0, 92.2% identity in 307 aa and to MMP1_MYCAV|Q48899 Mycobacterium avium major membrane protein I mmpI (307 aa), fasta scores: E(): 0, 89.6% identity in 308 aa. Previously sequenced as P46841. ML0841 encodes a dominant antigen (see Winter et al., 1995).;UniProt_AC=P46841;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	796048	797250	.	-	0	Locus=ML0660c;Name=fadE23;Function=;Product=Probable acyl-CoA dehydrogenase FadE23;Comments=ML0660c, len: 400 aa. Probable fadE23, acyl-CoA dehydrogenase (1.3.99.-), highly similar to P95186|AL123456|Rv3140 fadE23, probable acyl-CoA dehydrogenase from M. tuberculosis (401 aa), Fasta scores: E(): 0, (89.5% identity in 401 aa overlap); and CAD95256|Mb3164 from M. bovis (401 aa). Similar to many e.g. Q9HUH1 Probable acyl-CoA dehydrogenase from Pseudomonas aeruginosa (402 aa), fasta scores: opt: 1550, E(): 4.7e-97, (60.0% identity in 400 aa overlap). Also similar to ML0737. Previously sequenced as O32891|Z98271 (400 aa), Fasta scores: E(): 0, (100.0% identity in 400 aa overlap). Contains 2 Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. COULD BELONG TO THE ACYL-CoA DEHYDROGENASES FAMILY.;UniProt_AC=O32891;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	465203	466624	.	+	0	Locus=ML0373;Name=ML0373;Function=;Product=Conserved hypothetical protein;Comments=ML0373, len: 473 aa. Conserved hypothetical protein, highly similar to Rv3433c|YY33_MYCTU|O06250 conserved hypothetical protein from M. tuberculosis (473 aa), Fasta scores: E(): 0, (84.6% identity in 473 aa overlap). Similar to many bacterial hypothetical proteins e.g. O86783|SC6G4.20c from Streptomyces coelicolor (485 aa), Fasta scores: E(): 0, (49.1% identity in 489 aa overlap). Previously sequenced as YY33_MYCLE|P37391 (392 aa), Fasta scores: E(): 0, (94.5% identity in 381 aa overlap). Contains Pfam match to entry PF01256 UPF0031, Uncharacterized protein family UPF0031. Contains PS01049 Uncharacterized protein family UPF0031 signature 1. Contains PS01050 Uncharacterized protein family UPF0031 signature 2.;UniProt_AC=P37391;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	801977	803347	.	-	0	Locus=ML0666c;Name=fprA;Function=;Product=Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE);Comments=ML0666c, len: 456 aa. Probable fprA, NADPH:adrenodoxin oxidoreductase (NADPH-ferredoxin reductase) (EC 1.18.1.2), highly similar to O05783|AL123456|Rv3106 fprA, NADPH:adrenodoxin oxidoreductase from M. tuberculosis (456 aa), Fasta scores: E(): 0, (80.8% identity in 459 aa overlap); and CAD96820|Mb3133 from M. bovis (456 aa). Also similar to other adrenodoxin oxidoreductases e.g. Q9RX19 Putative NADPH:adrenodoxin oxidoreductase from   Deinococcus radiodurans (479 aa), fasta scores: opt: 1302, E(): 2.6e-76, (46.799% identity in 453 aa overlap). Also similar to ML2134. Previously sequenced as O32886|Z98271 (456 aa), Fasta scores: E(): 0, (99.8% identity in 456 aa overlap).;UniProt_AC=O32886;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	694890	695909	.	+	0	Locus=ML0570;Name=gap;Function=;Product=Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH);Comments=ML0570, len: 339 aa. Probable gap, Glyceraldehyde 3-phosphate dehydrogenase (EC 1.2.1.12), highly similar to G3P_MYCTU|O06822|Rv1436 gap, Glyceraldehyde 3-phosphate dehydrogenase from M. tuberculosis (339 aa), Fasta scores: E(): 3.6e-124, (89.1% identity in 339 aa overlap); and CAD94332|Mb1471 from M. bovis (339 aa). Similar to many e.g. G3P_MYCAV|P94915 gap, glyceraldehyde 3-phosphate dehydrogenase from Mycobacterium avium (339 aa), Fasta scores: E(): 0, (87.9% identity in 339 aa overlap). Previously sequenced as G3P_MYCLE|P46713 (339 aa), Fasta scores: E(): 0, (99.7% identity in 339 aa overlap). Contains Pfam match to entry PF00044 gpdh, glyceraldehyde 3-phosphate dehydrogenases. Contains PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. Belongs to the Glyceraldehyde 3-phosphate dehydrogenase family.;UniProt_AC=P46713;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	385650	386630	.	+	0	Locus=ML0303;Name=glnH;Function=;Product=Probable glutamine-binding protein GlnH (GLNBP);Comments=ML0303, len: 326 aa. Probable glnH, glutamine-binding protein, membrane-bound lipoprotein (see citation below), highly similar to Rv0411c|P96257|AL123456 glnH, glutamine-binding protein from M. tuberculosis (328 aa), Fasta scores: E(): 0, (79.3% identity in 328 aa overlap). Similar to many bacterial solute-binding proteins e.g. GLNH_BACST|P27676 glnH, glutamine-binding protein from Bacillus stearothermophilus (262 aa), Fasta scores: E(): 3.7e-23, (38.1% identity in 194 aa overlap). Previously sequenced as Q9ZBL7|AL035159 (325 aa), Fasta scores: E(): 0, (100.0% identity in 325 aa overlap). Contains a probable N-terminal signal sequence. Contains Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3. Contains PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Belongs to the bacterial solute-binding protein family 3. Presumed attached to the membrane by a lipid anchor.;UniProt_AC=Q9CCX0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	473559	475172	.	+	0	Locus=ML0381;Name=groEL1;Function=;Product=60 kDa chaperonin 1 GroEL1 (Protein Cpn60-1) (groEL protein 1);Comments=ML0381, len: 537 aa. groEL1 (alternate genbe name: cpn60_1), 60 kDa chaperonin 1 (protein cpn60 1) (see citations below), highly similar to Rv3417c|CH61_MYCTU|Q59573 groEL1, 60 kDa chaperonin 1 from M. tuberculosis (539 aa), Fasta scores: E(): 0, (82.9% identity in 539 aa overlap). Also highly similar to others e.g. P40171|CH61_STRCO|GROL1|GROEL1|SC6G4.40 from Streptomyces coelicolor (540 aa), Fasta scores: E(): 0, (82.9% identity in 539 aa overlap). Previously sequenced as CH61_MYCLE|P37578 (537 aa), Fasta scores: E(): 0, (100.0% identity in 537 aa overlap). Contains Pfam match to entry PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family. Contains PS00296 Chaperonins cpn60 signature. Belongs to the chaperonin (hsp60) family.;UniProt_AC=P37578;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	447415	448962	.	+	0	Locus=ML0354;Name=ilvX;Function=;Product=Probable acetohydroxyacid synthase IlvX (acetolactate synthase);Comments=ML0354, len: 515 aa. Probable ilvX, acetohydroxyacid synthase (EC 4.1.3.18), highly similar to Rv3509c|O53554|AL123456 ilvX, probable acetohydroxyacid synthase from M. tuberculosis (515 aa), Fasta scores: E(): 0, (82.9% identity in 515 aa overlap). Also similar to various enzymes (principally acetohydroxyacid/acetolactate synthases) e.g. ILVI_ECOLI|P00893 ilvI, acetolactate synthase isozyme III large subunit from Escherichia coli (574 aa), Fasta scores: E(): 1.8e-07, (23.7% identity in 540 aa overlap); and MDLC_PSEPU|P20906 mdlC, benzoylformate decarboxylase from Pseudomonas putida (528 aa), Fasta scores: E(): 6.6e-13, (29.3% identity in 529 aa overlap). Previously sequenced as Q49865|U00020 (515 aa), Fasta scores: E(): 0, (99.8% identity in 515 aa overlap). Contains 2 Pfam matches to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzymes.;UniProt_AC=Q49865;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	423179	423937	.	-	0	Locus=ML0333c;Name=ML0333c;Function=;Product=Conserved hypothetical protein;Comments=ML0333c, len: 252 aa. Conserved hypothetical protein. N-terminal half is similar to LAMB_EMENI|P38096 lamB, lactam utilization protein from Emericella nidulans (262 aa), Fasta scores: E(): 2.6e-15, (38.3% identity in 128 aa overlap). Similar to many bacterial hypothetical proteins e.g. Q9RL45|AL121596 conserved hypothetical protein SCF51A.19 from Streptomyces coelicolor A3(2) (250 aa), Fasta scores: E(): 0, (58.1% identity in 248 aa overlap).;UniProt_AC=Q9CCW2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1179522	1180502	.	-	0	Locus=ML1009c;Name=ML1009c;Function=;Product=conserved hypothetical protein;Comments=ML1009c, len: 326 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49847 (EMBL:U00019) (326 aa), Fasta scores: E(): 0, 100.0% identity in 326 aa overlap. Also highly similar to a number of other proteins of unknown function e.g. Mycobacterium tuberculosis Rv2714 TR:O07213 (EMBL:Z96072) (324 aa), Fasta scores: E(): 0, 89.7% identity in 320 aa overlap.;UniProt_AC=Q49847;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2424246	2424417	.	+	0	Locus=ML2033A;Name=ML2033A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2033A, len:171. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.003 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	907184	908416	.	+	0	Locus=ML0765;Name=manA;Function=;Product=probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHOSPHOHEXOMUTASE);Comments=ML0765, len: 410 aa. Probable manA, mannose-6-phosphate isomerase (EC 5.3.1.8), highly similar to Rv3255c|MTCY20B11.30c|O05898|Z95121 Probable manA, mannose-6-phosphate isomerase from M. tuberculosis (408 aa), fasta scores: E(): 2.6e-143, (84.4% identity in 411 aa overlap); and CAD95375|Mb3283c from M. bovis (408 aa). Similar to several e.g. Q9KZL9 Mannose-6-phosphate isomerase from Streptomyces coelicolor (383 aa), fasta scores: E(): 6.5e-54, (44.717% identity in 407 aa overlap); and MANA_HUMAN|P34949 mannose-6-phosphate isomerase from Homo sapiens (422 aa), fasta scores: E(): 1.2e-27, (31.0% identity in 432 aa overlap). Contains Pfam match to entry PF01238 PMI_typeI, Phosphomannose isomerase type I. SIMILAR TO FAMILY 1 OF MANNOSE-6-PHOSPHATE ISOMERASES.;UniProt_AC=Q9CCJ5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	895478	896554	.	+	0	Locus=ML0753;Name=manB;Function=INVOLVED IN GDP-MANNOSE BIOSYNTHESIS AND BIOSYNTHESIS OF NUCLEOTIDE-ACTIVATED GLYCERO-MANNO-HEPTOSE (D-ALPHA-D PATHWAY): GENERATES GDP-MANNOSE AND PHOSPHATE FROM GTP AND ALPHA-D-MANNOSE 1-PHOSPHATE. MANB PRODUCT IS NEEDED FOR ALL MANNOSYL GLYCOLIPIDS AND POLYSACCHARIDES WHICH, LIKE RHAMNOSYL RESIDUES, ARE AN IMPORTANT PART OF THE MYCOBACTERIUM ENVELOPE [CATALYTIC ACTIVITY: ALPHA-D-MANNOSE 1-PHOSPHATE + GTP = GDP-MANNOSE + PHOSPHATE].;Product=Probable D-alpha-D-mannose-1-phosphate guanylyltransferase ManB (D-ALPHA-D-HEPTOSE-1-PHOSPHATE GUANYLYLTRANSFERASE);Comments=ML0753, len: 358 aa. Probable manB (alternate gene name: hddC), D-alpha-D-mannose-1-phosphate guanylyltransferase (EC 2.7.7.-) (see citations below), highly similar to Rv3264c|MTCY71.04c|P96869|Z92771 manB D-alpha-D-mannose-1-phosphate guanylyltransferase from Mycobacterium tuberculosis (359 aa), fasta scores: E(): 0, (86.9% identity in 359 aa); and CAD95384|Mb3292c from M. bovis (359 aa). Similar to several e.g. Q8FRK5 Putative mannose-1-phosphate guanyltransferase  (372 aa), fasta scores: E(): 9.4e-93, (67.507% identity in 357 aa overlap); and Q9KZK6 Putative nucleotide phosphorylase from Streptomyces coelicolor (360 aa), fasta scores: E(): 6.7e-73, (56.704% identity in 358 aa overlap). Also similar to ML2503 from M. leprae. Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase. Contains 3 Pfam matches to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats). BELONGS TO FAMILY 2 OF MANNOSE-6-PHOSPHATE ISOMERASES. Note that previously known as rmlA2.;UniProt_AC=Q9CCK6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	551192	552241	.	-	0	Locus=ML0451c;Name=ML0451c;Function=;Product=Probable conserved membrane protein;Comments=ML0451c, len: 349 aa. Probable conserved membrane protein, highly similar to Rv2609c|O06205|AL123456 conserved membrane protein from M. tuberculosis (351 aa), Fasta scores: E(): 0, (77.7% identity in 336 aa overlap). Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17|O69888|AL023797 (172 aa), Fasta scores: E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as O07146|Z96801 (349 aa), Fasta scores: E(): 0, (100.0% identity in 349 aa overlap); and Q9RYE5|DR0004 mutT/nudIX family protein from Deinococcus radiodurans (350 aa). Contains a possible N-terminal signal sequence. Contains PS00893 mutT domain signature. Belongs to the mutT/nudIX family.;UniProt_AC=O07146;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	681704	682783	.	+	0	Locus=ML0564;Name=ML0564;Function=;Product=Conserved hypothetical protein;Comments=ML0564, len: 359 aa. Conserved hypothetical protein, highly similar to YE22_MYCTU|P71691|Rv1422 Conserved hypothetical protein from M. tuberculosis (342 aa), Fasta scores: E(): 6.8e-113, (85.7% identity in 350 aa overlap); and CAD94318|Mb1457 from M. bovis (342 aa). Conserved in other bacteria e.g. Q8FT62 Conserved hypothetical protein from Corynebacterium efficiens (356 aa), fasta scores: E(): 1.2e-64, (57.372% identity in 312 aa overlap). Contains a match to Pfam entry PF01933, Uncharacterised protein family UPF0052.;UniProt_AC=Q9CCN9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	693612	694427	.	-	0	Locus=ML0569c;Name=ML0569c;Function=;Product=Possible conserved exported protein;Comments=ML0569c, len: 271 aa. Possible conserved exported protein, highly similar to O06825|AL123456|Rv1433 Possible conserved exported protein from M. tuberculosis (271 aa), Fasta scores: E(): 0, (68.3% identity in 271 aa overlap); and CAD94329|Mb1468 from M. bovis (271 aa). Similar to ML0426, ML2446 and ML2664 from M. leprae. Shows similarity to other proteins in M. tuberculosis e.g. Rv2518c, Rv0116c, Rv0192, Rv0483. Previously sequenced as Q49706|U00013 (271 aa), Fasta scores: E(): 0, (100.0% identity in 271 aa overlap). Contains possible N-terminal signal sequence.;UniProt_AC=Q49706;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	714235	715032	.	-	0	Locus=ML0589c;Name=ML0589c;Function=;Product=Possible unidentified antibiotic-transport integral membrane protein ABC transporter;Comments=ML0589c, len: 265 aa. Possible unidentified antibiotic-transport integral membrane protein ABC transporter (see citation below), highly similar to O86349|AL123456|Rv1457c Possible unidentified antibiotic-transport integral membrane protein ABC transporter from M. tuberculosis (261 aa), Fasta scores: E(): 3.6e-74, (83.1% identity in 260 aa overlap); and CAD96159|Mb1492c from M. bovis (261 aa). Similar to other bacterial hypothetical membrane proteins e.g. O87317|AF027770 fxtE, hypothetical membrane protein from Mycobacterium smegmatis (236 aa), Fasta scores: E(): 1.6e-60, (77.1% identity in 236 aa overlap). Previously sequenced as Q49703|U00013 (265 aa), Fasta scores: E(): 0, (99.6% identity in 265 aa overlap). Contains hydrophobic, probable membrane-spanning regions.;UniProt_AC=Q49703;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	766711	767601	.	+	0	Locus=ML0634;Name=ML0634;Function=INVOLVED IN THE SYNTHESIS OF DECAPRENYL DIPHOSPHATE, A MOLECULE WHICH HAS A CENTRAL ROLE IN THE BIOSYNTHESIS OF MOST FEATURES OF THE MYCOBACTERIAL CELL WALL. ADDS SEVEN MORE ISOPRENE UNITS TO OMEGA,E, Z-FARNESYL DIPHOSPHATE AND RELEASES DECAPRENYL DIPHOSPHATE.;Product=Probable Long (C50) chain Z-isoprenyl diphosphate synthase (Z-DECAPRENYL DIPHOSPHATE SYNTHASE);Comments=ML0634, len: 296 aa. Probable Long (C50) chain Z-isoprenyl diphosphate synthase (EC 2.5.1.-), highly Similar to UPPS_MYCTU|O05837|Rv2361c Long (C50) chain Z-isoprenyl diphosphate synthase from M. tuberculosis (296 aa), Fasta scores: E(): 3.7e-104, (86.5% identity in 296 aa overlap); and CAD97243|Mb2382c from M. bovis. Similar to several Undecaprenyl pyrophosphate synthetases e.g. UPPS_MICLU|O82827 uppS, undecaprenyl pyrophosphate synthetase from Micrococcus luteus (249 aa), Fasta scores: E(): 5.4e-30, (39.4% identity in 246 aa overlap). Similar to ML2467. Previously sequenced as UPPS_MYCLE|P38119 (296 aa), Fasta scores: E(): 0, (99.7% identity in 296 aa overlap). Contains Pfam match to entry PF01255 UPP_synthetase, Putative undecaprenyl diphosphate synthase. Contains PS01066 Undecaprenyl pyrophosphate synthetase family signature. SEEMS TO BELONG TO THE UPP SYNTHETASE FAMILY.;UniProt_AC=P38119;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	897972	899639	.	-	0	Locus=ML0756c;Name=ML0756c;Function=;Product=probable DNA methylase (MODIFICATION METHYLASE) (METHYLTRANSFERASE);Comments=ML0756c, len: 555 aa. Probable DNA methylase (EC 2.1.1.-), highly similar to Rv3263|MTCY71.03|P96868|Z92771 Probable DNA methylase from Mycobacterium tuberculosis (553 aa), fasta scores: E(): 8.1e-195, (81.9% identity in 541 aa); CAD95383| from M. bovis (553 aa). Similar to several e.g. MT57_ECOLI|P25240 modification methylase eco57IM from Escherichia coli (544 aa), fasta scores: E(): 7.4e-36, (31.4% identity in 525 aa). Contains PS00092 N-6 Adenine-specific DNA methylases signature.;UniProt_AC=Q9CCK4;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	777177	780128	.	+	0	Locus=ML0644;Name=ML0644;Function=;Product=Probable conserved transmembrane protein;Comments=ML0644, len: 983 aa. Probable conserved transmembrane protein, with hydrophobic N-terminal domain, highly similar to O53339|AL123456|Rv3193c conserved transmembrane protein from M. tuberculosis (992 aa), Fasta scores: E(): 0, (86.1% identity in 989 aa overlap); and CAD95307|Mb3215c from M. bovis (992 aa). Also similar to O53609|AL123456|Rv0064 putative membrane protein from M. tuberculosis (979 aa), Fasta scores: E(): 5.3e-175, (49.3% identity in 984 aa overlap) and to other bacterial hypothetical membrane proteins. Previously sequenced as O32904|Z98271 (277 aa), Fasta scores: E(): 0, (100.0% identity in 277 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CCM6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	859918	860589	.	-	0	Locus=ML0717c;Name=ML0717c;Function=;Product=Probable transcriptional regulator (TetR-family);Comments=ML0717c, len: 223 aa. Probable transcriptional regulator tetR-family, highly similar to P96900|AL123456|Rv3295 putative TetR-family transcriptional regulator from M. tuberculosis (221 aa), Fasta scores: E(): 0, (85.5% identity in 220 aa overlap); and CAD95415|Mb3323 from M. bovis (221 aa). Similar to many putative transcriptional regulators e.g. Q9RD77|SCO0800|SCF43.11C Putative TetR-family transcriptional regulator from Streptomyces coelicolor (205 aa), fasta scores: opt: 443, E(): 4.9e-23, (39.500% identity in 200 aa overlap). Previously sequenced as Q49662|U00012 (242 aa), Fasta scores: E(): 0, (100.0% identity in 223 aa overlap). Contains a probable helix-turn-helix motif at aa 33-54 (Score 1535, SD +4.42) Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family. SIMILAR TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS.;UniProt_AC=Q9CCL4;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	892064	893533	.	-	0	Locus=ML0750c;Name=ML0750c;Function=;Product=conserved hypothetical protein (CPSA-RELATED PROTEIN);Comments=ML0750c, len: 489 aa. Conserved hypothetical protein, CPSA-related protein, highly similar to Rv3267|MTCY71.07|P96872|Z92771 Conserved hypothetical protein from Mycobacterium tuberculosis (498 aa), fasta scores: E(): 9.8e-150, (78.9% identity in 498 aa), and Rv3484|MTCY13E12.37|O06347|Z95390 cpsA from Mycobacterium tuberculosis (513 aa), fasta scores: E(): 1.6e-45, (34.5% identity in 502 aa). Also similar to hypothetical proteins from capsular polysaccharide biosynthesis loci (homologues of Streptococcus agalactiae cpsX, which may have a regulatory function) and to frnA from a Streptomyces roseofulvus polyketide biosynthesis locus. Similar to ML2247 from M. leprae.;UniProt_AC=Q9CCK9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	695912	697162	.	+	0	Locus=ML0571;Name=pgk;Function=;Product=Probable phosphoglycerate kinase Pgk;Comments=ML0571, len: 416 aa. Probable pgk, Phosphoglycerate kinase (EC 2.7.2.3), highly similar to PGK_MYCTU|O06821|Rv1437 pgk, phosphoglycerate kinase from M. tuberculosis (412 aa), Fasta scores: E(): 2.7e-129, (80.6% identity in 412 aa overlap); and CAD94333|Mb1472 from M. bovis (412 aa). Similar to many e.g. PGK_CORGL|Q01655 pgk, phosphoglycerate kinase from Corynebacterium glutamicum (403 aa), Fasta scores: E(): 7.4e-94, (59.2% identity in 407 aa overlap). Previously sequenced as PGK_MYCLE|P46712 (416 aa), Fasta scores: E(): 0, (99.8% identity in 416 aa overlap). Contains Pfam match to entry PF00162 PGK, Phosphoglycerate kinases. Contains PS00111 Phosphoglycerate kinase signature. Belongs to the Phosphoglycerate kinase family.;UniProt_AC=P46712;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	952105	953607	.	+	0	Locus=ML0803;Name=ML0803;Function=;Product=Probable two-component sensor kinase;Comments=ML0803, len: 500 aa. Probable two-component sensor kinase, highly similar to Rv3220c|MTCY07D11.06|O05846|Z95120 Probable two component sensor kinase from M. tuberculosis (501 aa), fasta scores: E(): 5.1e-165, (81.8% identity in 501 aa), and CAD95338|Mb3246c from M. bovis (501 aa). Similar to others e.g. Q82IW5 Putative two-component system sensor kinase from Streptomyces avermitilis (501 aa), fasta scores: E(): 3.9e-78, (45.892% identity in 499 aa overlap). Contains Pfam match to entry PF00512 signal, Histidine kinase. SEEMS SIMILAR TO OTHER PROKARYOTIC SENSORY TRANSDUCTION HISTIDINE KINASES.;UniProt_AC=Q9CCH8;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	575470	576141	.	+	0	Locus=ML0474;Name=snoP;Function=;Product=Probable glutamine amidotransferase SnoP;Comments=ML0474, len: 223 aa. Probable snoP, glutamine amidotransferase, highly similar to Rv2604c|O06210|AL123456 Probable snoP, glutamine amidotransferase from M. tuberculosis (198 aa), Fasta scores: E(): 0, (82.8% identity in 198 aa overlap). Similar to many bacterial hypothetical proteins and some similarity to amidotransferases e.g. Q9L287|SCL2.12c Hypothetical protein SCO1522 from Streptomyces coelicolor (202 aa), fasta scores: opt: 715, E(): 1.5e-41, (58.854% identity in 192 aa overlap); BAC74542|Q81ZV5 Putative glutamine amidotransferase from Streptomyces avermitilis (201 aa) fasta scores: opt: 709, E(): 3.9e-41, (59.896% identity in 192 aa overlap). Previously sequenced as Q49637|U00011 (219 aa), Fasta scores: E(): 0, (100.0% identity in 219 aa overlap). Contains Pfam match to entry PF01174 SNO glutamine amidotransferase family.;UniProt_AC=Q9CCT5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	569608	569709	.	-	0	Locus=ML0469A;Name=ML0469A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0469A, len:101. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	953667	953921	.	-	0	Locus=ML0804c;Name=whiB1;Function=;Product=Probable transcritional regulatory protein WhiB-like WhiB1;Comments=ML0804c, len: 84 aa. Probable whiB1, WhiB-like regulatory protein (see citation below), highly similar to Rv3219|MTCY07D11.07c|O05847|Z95120 whiB1, WhiB-like regulatory protein from Mycobacterium (84 aa), fasta scores: E(): 4e-38, (95.2% identity in 84 aa); and CAD95337|Mb3245 from M. bovis (84 aa).  Similar to Q9Z6E9|AF073300 whiB3 from Mycobacterium smegmatis fasta scores: E(): 2e-10, (43.2% identity in 81 aa); and to Q9X952 Hypothetical protein wblE from Streptomyces coelicolor (85 aa), fasta scores: E(): 2.3e-29, (72.840% identity in 81 aa overlap). Also similar to ML0382, ML0639, ML0760 and ML2307;UniProt_AC=Q9CCH7;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1055263	1055670	.	+	0	Locus=ML0888;Name=ML0888;Function=;Product=conserved hypothetical protein;Comments=ML0888, len: 135 aa. Conserved hypothetical protein.  Similar to Mycobacterium tuberculosis hypothetical protein Rv2186c|O53520|AL021957 (129 aa), Fasta scores: E(): 0, 80.0% identity in 130 aa overlap. Previously sequenced as Mycobacterium leprae hypothetical protein TR:O69576 (EMBL:AL022602) (135 aa), Fasta scores: E(): 0, 100.0% identity in 135 aa overlap.;UniProt_AC=O69576;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	949043	949450	.	-	0	Locus=ML0799c;Name=ML0799c;Function=;Product=conserved hypothetical protein;Comments=ML0799c, len: 135 aa. Conserved hypothetical protein, similar to the N terminus of Rv3224A Conserved hypothetical protein from M. tuberculosis (62 aa), fasta scores: E(): 0.086, (59.375% identity in 32 aa overlap) and the N terminus of Rv3224B Conserved hypothetical protein from M. tuberculosis (72 aa), E(): 4.6e-09, (60.00% identity in 70 aa overlap). Similar to Q9XCD9|AF144091 hypothetical 19.1 kDa protein from M. smegmatis (185 aa), fasta scores: E(): 1e-15, (60.2% identity in 93 aa) and to other hypothetical proteins e.g. YBAK_SALTY|P37174 Protein ybaK in Salmonella typhimurium (159 aa), fasta scores: E(): 6e-08, (40.9% identity in 88 aa).;UniProt_AC=Q9CCI0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1490902	1495770	.	+	0	Locus=ML1249;Name=gdh;Function=;Product=PROBABLE NAD-DEPENDENT GLUTAMATE DEHYDROGENASE GDH (NAD-GDH) (NAD-DEPENDENT GLUTAMIC DEHYDROGENASE);Comments=ML1249, len: 1622 aa. Probable gdh, NAD-dependent glutamate dehydrogenase (EC 1.4.1.2). Similar to several NAD-dependent glutamate dehydrogenase including: Mycobacterium tuberculosis Rv2476c TR:O53203 (EMBL:AL021246) (1624 aa), Fasta scores: E(): 0, 81.5% identity in 1634 aa overlap and Rickettsia prowazekii TR:Q9ZCI2 (EMBL:AJ235273) (1581 aa), Fasta scores: E(): 0, 32.9% identity in 1494 aa overlap.;UniProt_AC=Q9X7B2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1086008	1087033	.	+	0	Locus=ML0916;Name=ftsQ;Function=;Product=POSSIBLE CELL DIVISION PROTEIN FTSQ;Comments=ML0916, len: 341 aa. Possible ftsQ, cell division protein. Similar to many FtsQ-family proteins thought to be involved in septum formation e.g. Mycobacterium tuberculosis SW:FTSQ_MYCTU (SW:O06226) (314 aa), Fasta scores: E(): 0, 75.4% identity in 297 aa overlap and in parts to Corynebacterium glutamicum SW:FTSQ_CORGL (SW:O24745) (222 aa), Fasta scores: E(): 2.3e-13, 26.6% identity in 203 aa overlap. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9CCE5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1090814	1091104	.	+	0	Locus=ML0921;Name=ML0921;Function=;Product=Possible conserved transmembrane protein;Comments=ML0921, len: 96 aa. Possible conserved transmembrane protein. Similar to several proteins of unknown function e.g. Mycobacterium tuberculosis Rv2146c TR:O06230 (EMBL:Z95388) (96 aa), Fasta scores: E(): 2.8e-32, 88.5% identity in 96 aa overlap and Streptomyces coelicolor TR:Q9S2X3 (EMBL:AL109663) (94 aa), Fasta scores: E(): 2.9e-12, 40.7% identity in 86 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CCE0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	946526	948304	.	-	0	Locus=ML0798c;Name=ML0798c;Function=;Product=conserved hypothetical protein;Comments=ML0798c, len: 592 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis ATP/GTP binding protein Rv2787|MTV002.52|O33329|AL008967 fasta scores: E(): 0, 76.5% id in 587 aa and to other M. tuberculosis hypothetical proteins. C-terminal half is similar to that of ML0048 from M. leprae and also similar to ML1536. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CCI1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	951840	952055	.	+	0	Locus=ML0802;Name=ML0802;Function=;Product=Probable biotinylated protein homolog TB7.3;Comments=ML0802, len: 71 aa. Probable biotinylated protein TB7.3 homolog, highly similar to Rv3221c|MTCY07d11.05|O05845|Z95120 TB7.3, Biotinylated protein from Mycobacterium tuberculosis (71 aa), fasta scores: E(): 6.2e-19, (90.1% identity in 71 aa) and Q9XCD6|BTB7_MYCSM Biotinylated protein TB7.3 homolog from M. smegmatis (70 aa), fasta scores: E(): 9.8e-18, (85.507% identity in 69 aa overlap). Also similar to the C-terminal half of O54030|AJ002015 mmdC methylmalonyl-CoA decarboxylase, gamma-subunit from Propionigenium modestum (134 aa), fasta scores: E(): 3.4e-06, (42.9% identity in 70 aa). Contains Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzymes. Contains PS00445 FGGY family of carbohydrate kinases signature 2.;UniProt_AC=Q9CCH9;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1116233	1116556	.	+	0	Locus=ML0946;Name=ML0946;Function=;Product=conserved hypothetical protein;Comments=ML0946, len: 107 aa. Conserved hypothetical protein. Similar in part to several PE-PGRS family protein from M. tuberculosis e.g. Rv1441c|O06818|Z95844 PE-PGRS family protein (491 aa), Fasta scores: E(): 0.00066, (38.7% identity in 106 aa overlap). Identical to the previously sequenced O05568|Z94723 Mycobacterium leprae hypothetical protein (107 aa), Fasta scores: E(): 0, (100.0% identity in 107 aa overlap). Contains Pfam match to entry PF00934 PE, PE family.;UniProt_AC=O05568;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1185459	1185878	.	-	0	Locus=ML1015c;Name=ML1015c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML1015c, len: 139 aa. Probable conserved transmembrane protein. Almost identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49983 (EMBL:U15181) (162 aa), Fasta scores: E(): 0, 100.0% identity in 139 aa overlap. Also highly similar to Mycobacterium tuberculosis Rv2709 TR:O07210 (EMBL:Z96072) (148 aa), Fasta scores: E(): 0, 70.7% identity in 123 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CCB4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1013251	1013520	.	+	0	Locus=ML0853;Name=rpsO;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S15 RPSO;Comments=ML0853, len: 89 aa. Probable rpsO, 30s ribosomal protein S15,  highly similar to Mycobacterium tuberculosis 30S ribosomal protein S15 rpsO or Rv2785c or MTV002.50C SW:RS15_MYCTU (O33327) (89 aa) fasta scores: E(): 1.1e-32, 92.1% identity in 89 aa and to Bacillus stearothermophilus 30S ribosomal protein S15 rpsO SW:RS15_BACST (P05766) (88 aa) fasta scores: E(): 7.7e-22, 62.5% identity in 88 aa. Previously sequenced as SW:RS15_MYCLE (O32967). Contains Pfam match to entry PF00312 Ribosomal_S15, Ribosomal protein S15. Contains PS00362 Ribosomal protein S15 signature. BELONGS TO THE S15P FAMILY OF RIBOSOMAL PROTEINS.;UniProt_AC=O32967;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	604481	604942	.	+	0	Locus=ML0498A;Name=ML0498A;Function=;Product=probable dihydrodipicolinate synthetase(pseudogene);Comments=ML0498A, len:461. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 7.00E-30 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1364967	1365554	.	+	0	Locus=ML1166;Name=ML1166;Function=;Product=POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN;Comments=ML1166, len: 195 aa. Possible transcriptional regulatory protein. Previously sequenced Mycobacterium leprae hypothetical protein SW:YD32_MYCLE (P53424) (222 aa), Fasta scores: E(): 0, 100.0% identity in 195 aa overlap. Also highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv1332 SW:YD32_MYCTU (Q10643) (218 aa), Fasta scores: E(): 0, 74.4% identity in 195 aa overlap and Streptomyces coelicolor TR:Q9S2G6 (EMBL:AL096852) (202 aa), Fasta scores: E(): 1.5e-05, 34.6% identity in 188 aa overlap.;UniProt_AC=P53424;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	963596	963844	.	+	0	Locus=ML0814;Name=ML0814;Function=;Product=conserved hypothetical protein TB9.4 homolog;Comments=ML0814, len: 82 aa. Conserved hypothetical protein, similar to M.tuberculosis Rv3208A (90 aa), and similar to Streptomyces coelicolor hypothetical protein. FASTA scores: Rv3208A, E(): 3e-32, 82% identity in 82 aa; AL390975|AL390975_32 Streptomyces coelicolor (94 aa) E(): 2.5e-09; 47.945 % identity in 73 aa overlap.;UniProt_AC=Q9CCH1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	964704	965729	.	+	0	Locus=ML0816;Name=ML0816;Function=;Product=conserved hypothetical protein;Comments=ML0816, len: 341 aa. Conserved hypothetical protein. Similar to Rv3207c|MTCY07D11.19|O05859|Z95120 Mycobacterium tuberculosis hypothetical 31.0 kDa protein (285 aa), fasta scores: E(): 0, 80.6% identity in 284 aa, and to CAB94652|AL359215|SC2H12.28c Streptomyces coelicolor putative membrane protein  (314 aa), fasta scores: E(): 1e-13, 30.2% identity in 331 aa.;UniProt_AC=Q9CCG9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1040899	1041318	.	+	0	Locus=ML0876;Name=ML0876;Function=;Product=Possible conserved integral membrane protein;Comments=ML0876, len: 139 aa. Possible conserved integral membrane protein. Similar to Mycobacterium tuberculosis hypothetical 14.9 kDa protein Rv2199c or MTCY190.10C SW:YL99_MYCTU (Q10406) (139 aa) fasta scores: E(): 0, 91.4% identity in 139 aa and to Streptomyces coelicolor hypothetical proteins e.g. putative integral membrane protein SC6G10.27C TR:Q9X812 (EMBL:AL049497) (132 aa) fasta scores: E(): 6.2e-15, 38.8% identity in 139 aa.;UniProt_AC=Q9CCF0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	978255	978677	.	-	0	Locus=ML0825c;Name=ML0825c;Function=;Product=PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARSR-FAMILY);Comments=ML0825c, len: 140 aa. Probable transcriptional regulator, arsR family. Similar to Rv2358|MTCY27.22c|O05840|Z95208 Mycobacterium tuberculosis putative transcriptional regulator (135 aa) fasta scores: E(): 0, 72.9% identity in 140 aa. Contains a probable helix-turn-helix motif at aa 77-98 (Score 1179, SD +3.20) Contains Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family. Belongs to the ARSR family of transciptional regulators.;UniProt_AC=Q9CCG5;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	996359	997291	.	-	0	Locus=ML0839c;Name=cysK;Function=;Product=PROBABLE CYSTEINE SYNTHASE A CYSK (O-ACETYLSERINE SULFHYDRYLASE A) (O-ACETYLSERINE (THIOL)-LYASE A) (CSASE A);Comments=ML0839c, len: 310 aa. Probable cysK1, cysteine synthase A (EC 4.2.99.8). Similar to Mycobacterium tuberculosis cysteine synthase A cysK or Rv2334 or MTCY98.03 SW:CYSK_MYCTU (P95230) (310 aa) fasta scores: E(): 0, 85.8% identity in 310 aa, and to Spinacia oleracea cysteine synthase, chloroplast precursor cysK SW:CYSL_SPIOL (P32260) (383 aa) fasta scores: E(): 0, 59.2% identity in 309 aa. Previously sequenced as SW:CYSK_MYCLE (O32978). Also similar to ML2396 from M. leprae. Contains Pfam match to entry PF00291 S_T_dehydratase, Pyridoxal-phosphate dependent enzyme. Contains PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. BELONGS TO THE CYSTEINE SYNTHASE/CYSTATHIONINE BETA-SYNTHASE FAMILY. ;UniProt_AC=O32978;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2629988	2630050	.	-	0	Locus=ML2212A;Name=ML2212A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2212A, len:62. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-04 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1008080	1008931	.	+	0	Locus=ML0849;Name=ML0849;Function=;Product=conserved hypothetical protein;Comments=ML0849, len: 283 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 30.0 kDa protein Rv2325c or MTCY3G12.09 SW:YN25_MYCTU (P71887) (282 aa) fasta scores: E(): 0, 77.3% identity in 282 aa. Similar other bacterial hypothetical proteins e.g. to Bacillus halodurans YbaF protein ybaF TR:Q9Z9J1 (EMBL:AB017508) (265 aa) fasta scores: E(): 3.4e-10, 24.5% identity in 249 aa. Previously sequenced as TR:O32970 (EMBL:Z98741).;UniProt_AC=O32970;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1041505	1042386	.	+	0	Locus=ML0877;Name=mmpS3;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN MMPS3;Comments=ML0877, len: 293 aa. Similar to Mycobacterium tuberculosis putative membrane protein mmpS3 or Rv2198c or MTCY190.09C SW:MMS3_MYCTU (Q10390) (299 aa) fasta scores: E(): 0, 69.8% identity in 308 aa. Contains hydrophobic, possible membrane-spanning region. BELONGS TO THE MMPS FAMILY.;UniProt_AC=Q9CCE9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1022185	1023108	.	-	0	Locus=ML0860c;Name=ML0860c;Function=;Product=conserved hypothetical protein;Comments=ML0860c, len: 307 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 31.7 kDa protein Rv2216 or MTCY190.27 SW:YM16_MYCTU (Q10403) (301 aa) fasta scores: E(): 0, 84.2% identity in 297 aa. Similar to many hypothetical proteins from both bacteria and eukaryotes e.g. to Drosophila melanogaster CG8768 TR:Q9V6F9 (EMBL:AE003821) (297 aa) fasta scores: E(): 6.3e-26, 31.3% identity in 304 aa. Previously sequenced as SW:YM16_MYCLE (O32960).;UniProt_AC=O32960;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1023124	1024716	.	-	0	Locus=ML0861c;Name=sucB;Function=INVOLVED IN THE TRICARBOXYLIC ACID CYCLE. THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-COA & CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: 2-OXOGLUTARATE DEHYDROGENASE (E1), DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3)Involved in tricarboxylic acid cycle; converts 2-oxoglutarate to succinyl-CoA and CO2 [Catalytic activity: Succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide];Product=Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB;Comments=ML0861c, len: 530 aa. Probable sucB, dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E 2.3.1.61). Similar to Mycobacterium tuberculosis dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex sucB or Rv2215 or MTCY190.26 SW:ODO2_MYCTU (Q10381) (553 aa) fasta scores: E(): 0, 81.8% identity in 555 aa. Similar to Streptomyces seoulensis dihydrolipoamide acetyltransferase pdhB TR:Q9Z6I4 (EMBL:AF047034) (612 aa) fasta scores: E(): 0, 51.6% identity in 614 aa and to many succinyltransferases e.g. Escherichia coli dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex sucB SW:ODO2_ECOLI (P07016) (404 aa) fasta scores: E(): 0, 38.4% identity in 409 aa. Previously sequenced  s TR:O32959 (EMBL:Z98741. Contains 2 Pfam matches to entry PF00364 biotin_lipoyl, Biotin-requiring enzymes. Contains Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase (catalytic domain). Contains 2 x PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. Belongs to the 2-oxoacid dehydrogenase family. ;UniProt_AC=O32959;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1030184	1031290	.	+	0	Locus=ML0866;Name=ilvE;Function=;Product=PROBABLE BRANCHED-CHAIN AMINO ACID TRANSAMINASE ILVE;Comments=ML0866, len: 368 aa. Probable ilvE, branched-chain amino acid aminotransferase (EC 2.6.1.42). Similar to Mycobacterium tuberculosis probable branched-chain amino acid aminotransferase ilvE or Rv2210c or MTCY190.21C SW:ILVE_MYCTU (Q10399) (368 aa) fasta scores: E(): 0, 87.2% identity in 368 aa. Similar to many e.g. Mus musculus branched-chain amino acid aminotransferase (cytosolic) bcat1 or eca39 SW:BCAT_MOUSE (P24288) (386 aa) fasta scores: E(): 0, 41.0% identity in 329 aa. Previously sequenced as SW:ILVE_MYCLE (O32954). Contains Pfam match to entry PF01063 aminotran_4, Aminotransferase class IV. Contains PS00770 Aminotransferases class-IV signature.;UniProt_AC=O32954;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	621920	622114	.	+	0	Locus=ML0511A;Name=ML0511A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0511A, len:194. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 6.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1033204	1033893	.	-	0	Locus=ML0869c;Name=ML0869c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML0869c, len: 229 aa. Probable conserved transmembrane protein. Equivalent to Mycobacterium tuberculosis hypothetical protein Rv2206 (MTCY190.17, 236 aa). Two hydrophobic stretches in C-terminal part.  FASTA scores: opt: 1052, 67.5% identity in 237 aa overlap. Also similar to part of Streptomyces coelicolor putative integral membrane protein SC5F7.32 TR:Q9S2R7 (EMBL:AL096872) (251 aa) fasta scores: E(): 3.5e-14, 34.7% identity in 219 aa. Previously sequenced as TR:O32952 (EMBL:Z98741). Start changed since first submission, protein longer now.;UniProt_AC=Q9CCF6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1039785	1040846	.	+	0	Locus=ML0875;Name=ctaC;Function=INVOLVED IN AEROBIC RESPIRATION. SUBUNIT I AND II FORM THE FUNCTIONAL CORE OF THE ENZYME COMPLEX. ELECTRONS ORIGINATING IN CYTOCHROME C ARE TRANSFERRED VIA HEME A AND CU(A) TO THE BINUCLEAR CENTER FORMED BY HEME A3 AND CU(B) [Catalytic activity: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O];Product=PROBABLE TRANSMEMBRANE CYTOCHROME C OXIDASE (SUBUNIT II) CTAC;Comments=ML0875, len: 353 aa. Probable ctaC, transmembrane cytochrome C oxidase (subunit II). Similar to Mycobacterium tuberculosis probable cytochrome C oxidase polypeptide II precursor ctaC or Rv2200c or MTCY190.11C SW:COX2_MYCTU (Q10375) (363 aa) fasta scores: E(): 0, 85.3% identity in 340 aa. Shows weak similarity to many cytochrome oxidases e.g. to part of Acanthamoeba castellanii cytochrome C oxidase polypeptide I+II cox1/2 SW:COX1_ACACA (Q37370) (873 aa) fasta scores: E(): 7.1e-10, 28.5% identity in 221 aa. Contains hydrophobic, probable membrane-spanning regions. Contains Pfam match to entry PF00116 COX2, Cytochrome C oxidase subunit II. Contains PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. Belongs to the cytochrome c oxidase subunit 2 family. ;UniProt_AC=Q9CCF1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1047667	1048767	.	+	0	Locus=ML0883;Name=trpD;Function=;Product=Probable anthranilate phosphoribosyltransferase TrpD;Comments=ML0883, len: 366 aa. Probable trpD, anthranilate phosphoribosyltransferase (EC 2.4.2.18). Similar to Mycobacterium tuberculosis anthranilate phosphoribosyltransferase trpD or Rv2192c or MTCY190.03C SW:TRPD_MYCTU (Q10382) (370 aa) fasta scores: E(): 0, 80.1% identity in 362 aa. Similar to many e.g. Streptomyces coelicolor anthranilate phosphoribosyltransferase 1 trpD1 or SC6G10.20C SW:TRD1_STRCO (O68608) (354 aa) fasta scores: E(): 0, 48.8% identity in 363 aa. Previously sequenced as SW:TRPD_MYCLE (O69581). Contains Pfam match to entry PF00591 Glycos_transf_3, glycosyl transferase family.;UniProt_AC=O69581;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1050966	1052090	.	+	0	Locus=ML0885;Name=ML0885;Function=;Product=Putative secreted protein;Comments=ML0885, len: 374 aa. Putative secreted protein. Similar to Mycobacterium tuberculosis putative secreted protein Rv2190c or MTCY190.01c or MTV021.23C SW:YL90_MYCTU (Q10383; O53524) (385 aa) fasta scores: E(): 0, 69.2% identity in 386 aa. Similar to many putative secreted proteins from Streptomyces coelicolor e.g. putative NPL/P60 family secreted protein SCD63A.04C TR:CAB92656 (EMBL:AL356832) (347 aa) fasta scores: E(): 1.4e-13, 31.7% identity in 357 aa. Previously sequenced as TR:O69580 (EMBL:AL022602). Contains a probable N-terminal signal sequence. Contains Pfam match to entry PF00877 NLPC_P60, NLP/P60 family.;UniProt_AC=O69580;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1106682	1107825	.	-	0	Locus=ML0936c;Name=ML0936c;Function=;Product=Putative group II intron maturase-related protein (pseudogene).;Comments=ML0936c, len: 1144 bp. Possible pseudogene, similar to several maturases e.g. Q9MD87|AF218567 putative maturase from Cryphonectria parasitica (Cheshnut blight fungus) (778 aa), (blastx scores: 143); and Rv0071|O53616 Putative maturase from M. tuberculosis (235 aa), (blastx scores: 153). Belongs to the LEPREP family of dispersed repeats (see citation below);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1057966	1058700	.	+	0	Locus=ML0892;Name=ML0892;Function=;Product=Probable 1-acylglycerol-3-phosphate O-acyltransferase;Comments=ML0892, len: 244 aa. Probable 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51). Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69572 (EMBL:AL022602) (244 aa), Fasta scores: E(): 0, 100.0% identity in 244 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2182c TR:O53516 (EMBL:AL021957) (247 aa), Fasta scores: E(): 0, 79.8% identity in 247 aa overlap and several Streptomyces coelicolor putative acyltransferases e.g. TR:CAB76086 (EMBL:AL157956) (223 aa), Fasta scores: E(): 0, 51.1% identity in 221 aa overlap. Contains Pfam match to entry PF01553 Acyltransferase, Acyltransferase.;UniProt_AC=O69572;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1064346	1064750	.	+	0	Locus=ML0898;Name=ML0898;Function=;Product=conserved hypothetical regulatory protein;Comments=ML0898, len: 134 aa. Conserved hypothetical protein, possibly involved in regulation. Identical to the previously sequenced Mycobacterium leprae putative transcriptional regulator TR:O69567 (EMBL:AL022602) (134 aa), Fasta scores: E(): 0, 99.3% identity in 134 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2175c TR:O5350 (EMBL:AL021957) (146 aa), Fasta scores: E(): 0, 82.1% identity in 134 aa overlap. Contains a probable helix-turn-helix motif at aa 18-39 (Score 1581, SD +4.57);UniProt_AC=O69567;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1067603	1068517	.	+	0	Locus=ML0901;Name=ML0901;Function=;Product=conserved hypothetical protein;Comments=ML0901, len: 304 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69565 (EMBL:AL022602) (304 aa), Fasta scores: E(): 0, 99.7% identity in 304 aa overlap. Also highly similar to Mycobacterium tuberculosis  hypothetical protein Rv2172c TR:O53506 (EMBL:AL021957) (301 aa), Fasta scores: E(): 0, 80.9% identity in 299 aa overlap.;UniProt_AC=O69565;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1069305	1069937	.	-	0	Locus=ML0903c;Name=ML0903c;Function=;Product=conserved hypothetical protein;Comments=ML0903c, len: 210 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69563 (EMBL:AL022602) (210 aa), Fasta scores: E(): 0, 99.5% identity in 210 aa overlap. Also highly similar to another protein of undefined function from Mycobacterium tuberculosis TR:O53504 (EMBL:AL021957) (206 aa), Fasta scores: E(): 0, 76.7% identity in 210 aa overlap.;UniProt_AC=O69563;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1071031	1071462	.	+	0	Locus=ML0905;Name=ML0905;Function=;Product=conserved hypothetical protein;Comments=ML0905, len: 143 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YL66_MYCLE (SW:O69561) (143 aa), Fasta scores: E(): 0, 99.3% identity in 143 aa overlap. Also highly similar to many other proteins of undefined function including: Mycobacterium tuberculosis Rv2166c SW:YL66_MYCTU (SW:O06211) (143 aa), Fasta scores: E(): 0, 92.3% identity in 142 aa overlap and Escherichia coli SW:YABB_ECOLI (SW:P22186) (152 aa), Fasta scores: E(): 3.8e-11, 32.0% identity in 147 aa overlap.;UniProt_AC=O69561;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1092224	1092616	.	+	0	Locus=ML0923;Name=ML0923;Function=;Product=Probable transmembrane protein;Comments=ML0923, len: 130 aa. Probable transmembrane protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2144c TR:O06231 (EMBL:Z95388) (118 aa), Fasta scores: E(): 1.3e-12, 50.4% identity in 129 aa overlap. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9CCD9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1081703	1083307	.	+	0	Locus=ML0913;Name=ftsW;Function=;Product=FtsW-like protein FtsW;Comments=ML0913, len: 534 aa. Probable ftsW, cell division protein. Identical to the previously sequenced Mycobacterium leprae cell division protein, FtsW, TR:O69553 (EMBL:AL022602) (534 aa), Fasta scores: E(): 0, 99.8% identity in 534 aa overlap. Also highly similar many other FtsW-family proteins involved in cell wall formation e.g. from Mycobacterium tuberculosis FtsW-like protein SW:FTWH_MYCTU (SW:O06223) (524 aa), Fasta scores: E(): 0, 76.5% identity in 528 aa overlap and Escherichia coli FtsW SW:FTSW_ECOLI (SW:P16457) (414 aa), Fasta scores: E(): 3.6e-31, 37.0% identity in 370 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein. Contains PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. Contains PS00041 Bacterial regulatory proteins, araC family signature.;UniProt_AC=O69553;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1083304	1084527	.	+	0	Locus=ML0914;Name=murG;Function=;Product=ProbableUPD-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase MurG;Comments=ML0914, len: 407 aa. Probable UPD-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase (EC 2.4.1.-). Identical to the previously sequenced Mycobacterium leprae UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.-) SW:MURG_MYCLE (SW:O69552) (407 aa), Fasta scores: E(): 0, 99.8% identity in 407 aa overlap). Also highly similar to orthologues from Mycobacterium tuberculosis Rv2153c SW:MURG_MYCTU (SW:O06224) (410 aa), Fasta scores: E(): 0, 76.3% identity in 401 aa overlap and Escherichia coli SW:MURG_ECOLI (SW:P17443) (354 aa), Fasta scores: E(): 4.2e-21, 38.1% identity in 365 aa overlap. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=O69552;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1087299	1088438	.	+	0	Locus=ML0917;Name=ftsZ;Function=;Product=cell division protein FtsZ;Comments=ML0917, len: 379 aa. Probable ftsZ, cell division protein. Highly similar to many proteins essential for cell division including: Mycobacterium tuberculosis Rv2150c SW:FTSZ_MYCTU (O08378) (379 aa), Fasta scores: E(): 0, 96.6% identity in 379 aa overlap and Streptomyces griseus SW:FTSZ_STRGR (P45501) (407 aa), Fasta scores: E(): 0, 68.7% identity in 390 aa overlap. Contains Pfam match to entry PF00091 tubulin, Tubulin/FtsZ family. Contains PS01134 FtsZ protein signature 1. Contains PS01135 FtsZ protein signature 2.;UniProt_AC=Q9CCE4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1089207	1089989	.	+	0	Locus=ML0919;Name=ML0919;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML0919, len: 260 aa. Conserved hypothetical protein; could belong to the YGGS/YBL036C/F09E5.8 family. Similar to many proteins of unknown function including: Mycobacterium tuberculosis Rv2148c SW:YL48_MYCTU (O06228) (258 aa), Fasta scores: E(): 0, 73.6% identity in 258 aa overlap and Corynebacterium glutamicum SW:YFZ1_CORGL (O24748) (221 aa), Fasta scores: E(): 7e-22, 41.6% identity in 231 aa overlap. Contains a probable helix-turn-helix motif at aa 78-99 (Score 1061, SD +2.80) Contains Pfam match to entry PF01168 UPF0001, Uncharacterized protein family UPF0001. Contains PS01211 Uncharacterized protein family UPF0001 signature.;UniProt_AC=Q9CCE2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1090057	1090689	.	+	0	Locus=ML0920;Name=ML0920;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML0920, len: 210 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2147c TR:O06229 (EMBL:Z95388) (241 aa), Fasta scores: E(): 0, 83.5% identity in 218 aa overlap. Note the Mycobacterium leprae protein is 23 aa shorter.;UniProt_AC=Q9CCE1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1088461	1089210	.	+	0	Locus=ML0918;Name=yfiH;Function=;Product=conserved hypothetical protein YfiH;Comments=ML0918, len: 249 aa. Probable yfiH, conserved hypothetical protein. Similar to many proteins of unknown function including: Mycobacterium tuberculosis Rv2149c TR:O06227 (EMBL:Z95388) (250 aa), Fasta scores: E(): 0, 60.2% identity in 244 aa overlap  and Streptomyces griseus SW:YFIH_STRGR (P45496) (246 aa), Fasta scores: E(): 5.8e-21, 38.0% identity in 245 aa overlap. Note both of these examples are also found downstream of FtsZ. Belongs to the UPF0124 family. ;UniProt_AC=Q9CCE3;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1185906	1186229	.	+	0	Locus=ML1016;Name=ML1016;Function=;Product=conserved hypothetical protein;Comments=ML1016, len: 107 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae TR:Q49984 (EMBL:U15181) (107 aa), Fasta scores: E(): 0, 99.1% identity in 107 aa overlap. Also highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis conserved hypothetical protein Rv2708c TR:O07209 (EMBL:Z96072) (82 aa), Fasta scores: E(): 9.2e-29, 87.8% identity in 82 aa overlap.;UniProt_AC=Q49984;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1186216	1187208	.	-	0	Locus=ML1017c;Name=ML1017c;Function=;Product=probable conserved integral membrane protein;Comments=ML1017c, len: 330 aa. Probable conserved integral membrane protein. Identical to the previously sequenced Mycobacterium leprae TR:Q49985 (EMBL:U15181) (330 aa), Fasta scores: E(): 0, 100.0% identity in 330 aa overlap. Also highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis  possible membrane protein Rv2707 TR:O07208 (EMBL:Z96072) (324 aa), Fasta scores: E(): 0, 75.4% identity in 325 aa overlap.;UniProt_AC=Q49985;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1192725	1193375	.	-	0	Locus=ML1025c;Name=ML1025c;Function=;Product=possible conserved secreted protein;Comments=ML1025c, len: 216 aa. Possible conserved secreted protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49989 (EMBL:U15181) (216 aa), Fasta scores: E(): 0, 99.5% identity in 216 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2700 TR:O07202 (EMBL:Z96072) (216 aa), Fasta scores: E(): 0, 82.4% identity in 216 aa overlap. Contains a possible N-terminal signal sequence.;UniProt_AC=Q49989;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1193571	1193873	.	+	0	Locus=ML1026;Name=ML1026;Function=;Product=conserved hypothetical protein;Comments=ML1026, len: 100 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q4998. Also highly similar to hypothetical proteins from Mycobacterium tuberculosis Rv2699c TR:O07201 (EMBL:Z96072) (100 aa), Fasta scores: E(): 0, 96.0% identity in 100 aa overlap and Streptomyces coelicolor TR:O54130 (EMBL:AL021530) (98 aa), Fasta scores: E(): 3.4e-26, 70.4% identity in 98 aa overlap.;UniProt_AC=Q49990;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1193878	1194351	.	-	0	Locus=ML1027c;Name=ML1027c;Function=;Product=Probable transmembrane protein;Comments=ML1027c, len: 157 aa. Probable transmembrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49991 (EMBL:U15181) (157 aa), Fasta scores: E(): 0, 99.4% identity in 157 aa overlap. Also highly similar to proteins of unknown function from Mycobacterium tuberculosis Rv2698 TR:O07200 (EMBL:Z96072) (161 aa), Fasta scores: E(): 0, 78.9% identity in 161 aa overlap and Streptomyces coelicolor TR:O54132 (EMBL:AL021530) (154 aa), Fasta scores: E(): 1.1e-08, 33.6% identity in 149 aa overlap. Contains possible membrane spanning hydrophobic domains. Contains a probable helix-turn-helix motif at aa 87-108 (Score 1009, SD +2.62);UniProt_AC=Q49991;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1200582	1201136	.	-	0	Locus=ML1037c;Name=ML1037c;Function=;Product=conserved hypothetical protein;Comments=ML1037c, len: 184 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49999 (EMBL:U15181) (184 aa), Fasta scores: E(): 0, 99.5% identity in 184 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2683 TR:O07185 (EMBL:Z96072) (165 aa), Fasta scores: E(): 0, 73.8% identity in 164 aa overlap. Contains 2 Pfam matches to entry PF00571 CBS, CBS domain.;UniProt_AC=Q49999;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1209290	1210645	.	+	0	Locus=ML1044;Name=hemY;Function=;Product=PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO);Comments=ML1044, len: 451 aa. Probable hemY, protoporphyrinogen oxidase (EC 1.3.3.4). Identical to the previously sequenced Mycobacterium leprae protoporphyrinogen oxidase (EC 1.3.3.4) SW:PPOX_MYCLE (Q50008) (451 aa), Fasta scores: E(): 0, 100.0% identity in 451 aa overlap. Also highly similar to many others including: Mycobacterium tuberculosis Rv2677c SW:PPOX_MYCTU (O53230) (426 aa), Fasta scores: E(): 0, 75.8% identity in 429 aa overlap and Bacillus subtilis SW:PPOX_BACSU (P32397) (470 aa), Fasta scores: E(): 2.2e-13, 27.1% identity in 458 aa overlap. Contains Pfam match to entry PF01208 URO-D, Uroporphyrinogen decarboxylase (URO-D). BELONGS TO THE PROTOPORPHYRINOGEN OXIDASE FAMILY. COFACTOR: CONTAINS ONE FAD PER HOMODIMER. ;UniProt_AC=Q50008;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1205250	1206539	.	-	0	Locus=ML1040c;Name=ML1040c;Function=;Product=conserved hypothetical protein;Comments=ML1040c, len: 429 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q50004 (EMBL:U15181) (429 aa), Fasta scores: E(): 0, 100.0% identity in 429 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2681 TR:O07183 (EMBL:Z96072) (438 aa), Fasta scores: E(): 0, 77.4% identity in 416 aa overlap. The predicted product of this CDS is also weakly similar to several nucleases e.g. Escherichia coli SW:RND_ECOLI (P09155) (375 aa), Fasta scores: E(): 2.4e-08, 26.7% identity in 371 aa overlap ribonuclease D (EC 3.1.26.3). Contains Pfam match to entry PF01612 3_5_exonuclease, 3'-5' exonuclease.;UniProt_AC=Q50004;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1206541	1207131	.	-	0	Locus=ML1041c;Name=ML1041c;Function=;Product=conserved hypothetical protein;Comments=ML1041c, len: 196 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q50005 (EMBL:U15181) (196 aa), Fasta scores: E(): 0, 99.5% identity in 196 aa overlap. Also highly similar to hypothetical proteins from Mycobacterium tuberculosis Rv2680 TR:O86317 (EMBL:Z96072) (210 aa), Fasta scores: E(): 0, 83.9% identity in 193 aa overlap and Streptomyces coelicolor TR:O69860 (EMBL:AL023702) (238 aa), Fasta scores: E(): 2.9e-25, 43.5% identity in 186 aa overlap.;UniProt_AC=Q50005;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1230647	1230991	.	+	0	Locus=ML1065;Name=ML1065;Function=;Product=conserved hypothetical protein;Comments=ML1065, len: 114 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49955. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1209 TR:O05310 (EMBL:Z93777) (122 aa), Fasta scores: E(): 1.3e-27, 78.6% identity in 112 aa overlap. Note the N-terminus of this protein is rich in the amino acid valine producing a possible membrane spanning hydrophobic domain.;UniProt_AC=Q49956;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	634112	634255	.	+	0	Locus=ML0523A;Name=ML0523A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0523A, len:143. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1292141	1292704	.	+	0	Locus=ML1116;Name=lprC;Function=;Product=POSSIBLE LIPOPROTEIN LPRC;Comments=ML1116, len: 187 aa. Possible lprC, lipoprotein. Highly similar to Mycobacterium tuberculosis putative lipoprotein LrpC Rv1275 TR:O86337 (EMBL:Z77137) (180 aa), Fasta scores: E(): 0, 82.7% identity in 179 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CC86;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1228779	1229654	.	+	0	Locus=ML1063;Name=folP2;Function=;Product=PROBABLE DIHYDROPTEROATE SYNTHASE 2 FOLP2 (DHPS 2) (Dihydropteroate pyrophosphorylase 2);Comments=ML1063, len: 291 aa. Probable folP2, dihydropteroate synthase 2 (EC 2.5.1.15). Identical to the previously sequenced Mycobacterium leprae dihydropteroate synthase (EC 2.5.1.15) SWDHPS_MYCLE:. Also highly similar to dihydropteroate synthases from Mycobacterium tuberculosis Rv1207 SW:DHP2_MYCTU (O05308) (318 aa), Fasta scores: E(): 0, 86.2% identity in 290 aa overlap and Escherichia coli SW:DHPS_ECOLI (P26282) (282 aa), Fasta scores: E(): 7.2e-24, 34.4% identity in 270 aa overlap. Also similar to ML0224 from M. leprae. Contains Pfam match to entry PF00809 DHPS, Dihydropteroate synthase. Contains PS00793 Dihydropteroate synthase signature 2. Contains PS00792 Dihydropteroate synthase signature 1.;UniProt_AC=P0C0X2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1222696	1223649	.	-	0	Locus=ML1058c;Name=ML1058c;Function=;Product=PROBABLE TRANSFERASE;Comments=ML1058c, len: 317 aa.  Probable tranferase (EC 2.-.-.-). Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49948 (EMBL:U15180) (317 aa), Fasta scores: E(): 0, 99.7% identity in 317 aa overlap and highly similar to Mycobacterium tuberculosis TR:O05302 (EMBL:Z93777) (317 aa), Fasta scores: E(): 0, 84.9% identity in 317 aa overlap. The C-terminus of this protein is also similar to many different transferases e.g. Haemophilus influenzae SW:DAPD_HAEIN (P45284) (275 aa), Fasta scores: E(): 0.00048, 26.7% identity in 131 aa overlap 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase (EC 2.3.1.117).;UniProt_AC=Q49948;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1226445	1227008	.	+	0	Locus=ML1061;Name=ML1061;Function=;Product=conserved hypothetical protein;Comments=ML1061, len: 187 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49952 (EMBL:U15180) (187 aa), Fasta scores: E(): 0, 100.0% identity in 187 aa overlap. Also highly similar to Mycobacterium tuberculosis TR:O05306 (EMBL:Z93777) (187 aa), Fasta scores: E(): 0, 72.4% identity in 174 aa overlap.;UniProt_AC=Q49952;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1249763	1250677	.	+	0	Locus=ML1087;Name=sugA;Function=;Product=PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGA;Comments=ML1087, len: 304 aa. Probable sugA, sugar-transport integral membrane protein ABC transporter. Previously sequenced Mycobacterium leprae MalF TR:Q49976 (EMBL:U15180) (310 aa), Fasta scores: E(): 0, 100.0% identity in 304 aa overlap. Also highly similar to many putative membrane transport proteins including: Mycobacterium tuberculosis probable sugar transport protein Rv1236 TR:O50452 (EMBL:AL021006) (307 aa), Fasta scores: E(): 0, 81.8% identity in 292 aa overlap and Thermococcus litoralis inner membrane protein MalF TR:O51924 (EMBL:AF012836) (300 aa), Fasta scores: E(): 0, 39.1% identity in 279 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component.;UniProt_AC=Q9CCA2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1371785	1372447	.	+	0	Locus=ML1175;Name=ML1175;Function=;Product=conserved hypothetical protein;Comments=ML1175, len: 220 aa. Conserved hypothetical protein. Previously sequenced Mycobacterium leprae hypothetical protein TR:Q9S383 (EMBL:AL049191) (220 aa), Fasta scores: E(): 0, 99.5% identity in 220 aa overlap. Also highly similar to many other proteins of undefined function including: Mycobacterium tuberculosis Rv1341 SW:YD41_MYCTU (Q10649) (204 aa), Fasta scores: E(): 0, 82.4% identity in 205 aa overlap and Escherichia coli SW:YGGV_ECOLI (P52061) (197 aa), Fasta scores: E(): 1e-23, 44.8% identity in 203 aa overlap. Contains Pfam match to entry PF01725 Ham1p_like, Ham1 family.;UniProt_AC=P52063;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1254674	1255663	.	+	0	Locus=ML1091;Name=mdh;Function=;Product=PROBABLE MALATE DEHYDROGENASE MDH;Comments=ML1091, len: 329 aa. Probable mdh, Malate dehydrogenase (EC 1.1.1.37). Identical to the previously sequenced Mycobacterium leprae malate dehydrogenase SW:MDH_MYCLE (P50917) (329 aa), Fasta scores: E(): 0, 99.7% identity in 329 aa overlap. Also highly similar to many other malate dehydrogenases including: Mycobacterium tuberculosis Rv1240 SW:MDH_MYCTU (O54592) (329 aa), Fasta scores: E(): 0, 89.1% identity in 329 aa overlap and Thermus aquaticus SW:MDH_THEFL (P10584) (327 aa), Fasta scores: E(): 0, 63.7% identity in 325 aa overlap. Contains Pfam match to entry PF00056 ldh, lactate/malate dehydrogenase. Contains PS00687 Aldehyde dehydrogenases glutamic acid active site. Contains PS00068 Malate dehydrogenase active site signature. BELONGS TO THE LDH FAMILY. MDH SUBFAMILY.;UniProt_AC=P50917;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1263935	1264609	.	-	0	Locus=ML1096c;Name=ML1096c;Function=;Product=POSSIBLE MEMBRANE PROTEIN;Comments=ML1096c, len: 224 aa. Possible membrane protein. Highly similar to Mycobacterium tuberculosis Rv1249c TR:O50464 (EMBL:AL021006) (262 aa), Fasta scores: E(): 0, 67.3% identity in 223 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CC96;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1301393	1303222	.	-	0	Locus=ML1122c;Name=oppD;Function=;Product=PROBABLE OLIGOPEPTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER OPPD;Comments=ML1122c, len: 609 aa. Probable oppD, oligopeptide-transport ATP-binding protein ABC transporter. Highly similar to many putative ABC transport proteins e.g. Escherichia coli SW:YLIA_ECOLI (P75796) (269 aa), BlastP Expect 4.0e-28 Mycobacterium tuberculosis Rv1281c SW:YC81_MYCTU (Q11040 (269 aa), BlastP Expect 4.0e-28. Note, that the N- and C-termini of this CDS are possible duplicates. Contains 2 Pfam matches to entry PF00005 ABC_tran, ABC transporter. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop). Contains 2 x PS00211 ABC transporters family signature. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).;UniProt_AC=Q9CC81;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1372488	1372847	.	-	0	Locus=ML1176c;Name=ML1176c;Function=;Product=CONSERVED MEMBRANE PROTEIN;Comments=ML1176c, len: 119 aa. Conserved membrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD42_MYCLE (P54133) (119 aa), Fasta scores: E(): 0, 100.0% identity in 119 aa overlap. Also highly similar to hypothetical proteins from Mycobacterium tuberculosis Rv1342c TR:YD42_MYCTU and Streptomyces coelicolor TR:Q9X948 (EMBL:AJ237976) (109 aa), Fasta scores: E(): 7.7e-11, 36.5% identity in 96 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=P54133;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	793952	794020	.	+	0	Locus=ML0656A;Name=ML0656A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0656A, len:68. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.002 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1304115	1305092	.	-	0	Locus=ML1124c;Name=oppB;Function=;Product=PROBABLE OLIGOPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER OPPB;Comments=ML1124c, len: 325 aa. Probable oppB, oligopeptide-transport integral membrane protein ABC transporter. Highly similar to many membrane transport proteins e.g. Mycobacterium tuberculosis putative peptide transport permease protein Rv1283c SW:YC83_MYCTU (Q10611) (325 aa), Fasta scores: E(): 0, 83.4% identity in 325 aa overlap and Bacillus subtilis oligopeptide transport system permease SW:APPB_BACSU (P42062) (317 aa), Fasta scores: E(): 4.5e-27, 34.1% identity in 328 aa overlap. Contains possible membrane spanning hydrophobic domains and a possible N-terminal signal sequence. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign.;UniProt_AC=Q9CC79;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1322117	1323064	.	+	0	Locus=ML1131;Name=thrB;Function=;Product=PROBABLE HOMOSERINE KINASE THRB;Comments=ML1131, len: 315 aa. Probable thrB, homoserine kinase (EC 2.7.1.39). Identical to the previously sequenced Mycobacterium leprae homoserine kinase (EC 2.7.1.39) SW:KHSE_MYCLE (P45836) (314 aa), Fasta scores: E(): 0, 99.7% identity in 314 aa overlap. Also highly similar to many other homoserine kinases including: Mycobacterium tuberculosis Rv1296 SW:KHSE_MYCTU (Q10603) (316 aa), Fasta scores: E(): 0, 82.0% identity in 311 aa overlap and Corynebacterium glutamicum SW:KHSE_CORGL (P08210) (308 aa), Fasta scores: E(): 0, 48.7% identity in 312 aa overlap. Contains Pfam match to entry PF00288 GHMP_kinases, GHMP kinases putative ATP-binding proteins. Contains PS00627 GHMP kinases putative ATP-binding domain.;UniProt_AC=P45836;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1320967	1322049	.	+	0	Locus=ML1130;Name=thrC;Function=;Product=PROBABLE THREONINE SYNTHASE THRC;Comments=ML1130, len: 360 aa. Probable thrC, threonine synthase (EC 4.2.99.2). Identical to the previously sequenced Mycobacterium leprae probable threonine synthase SW:THRC_MYCLE (P45837;) (360 aa), Fasta scores: E(): 0, 99.7% identity in 360 aa overlap. Also highly similar to many other threonine synthases e.g. Mycobacterium tuberculosis Rv1295 SW:THRC_MYCTU (Q10610) (360 aa), Fasta scores: E(): 0, 94.9% identity in 354 aa overlap and Brevibacterium lactofermentum SW:THRC_BRELA (P09123) (352 aa), Fasta scores: E(): 0, 57.9% identity in 337 aa overlap. Contains Pfam match to entry PF00291 S_T_dehydratase, Pyridoxal-phosphate dependent enzyme. Contains PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.;UniProt_AC=P45837;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1332059	1333399	.	+	0	Locus=ML1142;Name=atpH;Function=;Product=PROBABLE ATP SYNTHASE DELTA CHAIN ATPH;Comments=ML1142, len: 446 aa. Probable atpH, ATP synthase delta chain (EC 3.6.3.14). Previously sequenced Mycobacterium leprae SW:ATPD_MYCLE (P53006) (446 aa), Fasta scores: E(): 0, 100.0% identity in 446 aa overlap. The N-terminus of this protein shares high sequence identity with many ATP synthase B chain proteins e.g. Haemophilus influenzae SW:ATPF_HAEIN (P43720) (156 aa), Fasta scores: E(): 4.8e-05, 24.8% identity in 153 aa overlap and the C-terminus shares high homology with many ATP synthase [delta] chain proteins e.g. Streptomyces lividans SW:ATPD_STRLI (P50008) (272 aa), Fasta scores: E(): 3.4e-20, 33.1% identity in 266 aa overlap_ATP. Also highly similar over the entire range to Mycobacterium tuberculosis Rv1307 SW:ATPD_MYCTU (Q10594) (446 aa), Fasta scores: E(): 0, 77.8% identity in 446 aa overlap. Contains possible coiled-coils and a possible N-terminal signal sequence. Contains Pfam match to entry PF00213 OSCP, ATP synthase delta (OSCP) subunit. Contains Pfam match to entry PF00430 ATP-synt_B, ATP synthase B/B' CF(0). Contains PS01094 Uncharacterized protein family UPF0076 signature.;UniProt_AC=P53006;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	805539	805782	.	+	0	Locus=ML0668A;Name=ML0668A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0668A, len:243. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.021 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1338890	1339465	.	-	0	Locus=ML1149c;Name=ML1149c;Function=;Product=conserved hypothetical protein;Comments=ML1149c, len: 191 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa), Fasta scores: E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa), Fasta scores: E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function.;UniProt_AC=P53523;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1354283	1355188	.	+	0	Locus=ML1159;Name=ML1159;Function=;Product=POSSIBLE THIOREDOXIN;Comments=ML1159, len: 301 aa. Possible thioredoxin. Previously sequenced Mycobacterium leprae TR:Q49716 (EMBL:U00014) (255 aa), Fasta scores: E(): 0, 100.0% identity in 217 aa overlap. Highly similar to Mycobacterium tuberculosis Rv1324 SW:YD24_MYCTU (Q10636) (304 aa), Fasta scores: E(): 0, 72.4% identity in 301 aa overlap. Also weakly similar in parts to several putative thioredoxins e.g. Alicyclobacillus acidocaldarius SW:THIO_ALIAC (P80579) (105 aa), Fasta scores: E(): 0.00045, 27.1% identity in 107 aa overlap.;UniProt_AC=Q9CC76;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1801374	1801727	.	-	0	Locus=ML1494c;Name=ML1494c;Function=;Product=conserved transmembrane protein;Comments=ML1494c, len: 117 aa. Probable integral membrane protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1171 TR:O50427 (EMBL:AL010186) (146 aa), Fasta scores: E(): 7.4e-24, 62.2% identity in 111 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CBX5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1370099	1370881	.	+	0	Locus=ML1173;Name=ML1173;Function=;Product=conserved hypothetical protein;Comments=ML1173, len: 260 aa. Conserved hypothetical protein. Previously sequenced Mycobacterium leprae hypothetical protein SW:YD39_MYCLE (P50474) (284 aa), Fasta scores: E(): 0, 100.0% identity in 260 aa overlap. Also highly similar to several other proteins of unknown function e.g. Mycobacterium tuberculosis Rv1339 SW:YD39_MYCTU and Streptomyces coelicolor TR:Q9S2H3 (EMBL:AL096852) (250 aa), Fasta scores: E(): 0, 43.0% identity in 256 aa overlap.;UniProt_AC=P50474;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1370971	1371750	.	+	0	Locus=ML1174;Name=rphA;Function=RNase PH IS A PHOSPHOROLYTIC EXORIBONUCLEASE THAT REMOVES NUCLEOTIDE RESIDUES FOLLOWING THE -CCA TERMINUS OF tRNA AND ADDS NUCLEOTIDES TO THE ENDS OF RNA MOLECULES BY USING NUCLEOSIDE DIPHOSPHATES AS SUBSTRATES [CATALYTIC ACTIVITY: {TRNA}(N+1) + PHOSPHATE = {TRNA}(N) + A NUCLEOSIDE DIPHOSPHATE].;Product=PROBABLE RIBONUCLEASE RPHA (RNase PH) (tRNA nucleotidyltransferase);Comments=ML1174, len: 259 aa. Probable rphA ribonuclease (EC 2.7.7.56). Identical to the previously sequenced Mycobacterium leprae probable ribonuclease PH SW:RNPH_MYCLE (P37939) (259 aa), Fasta scores: E(): 0, 99.6% identity in 259 aa overlap. Also highly similar to many other ribonucleases including: Mycobacterium tuberculosis Rv1340 SW:RNPH_MYCTU (Q10628) (259 aa), Fasta scores: E(): 0, 88.8% identity in 259 aa overlap and Escherichia coli SW:RNPH_ECOLI (P03842) (238 aa), Fasta scores: E(): 0, 55.7% identity in 237 aa overlap. Contains Pfam match to entry PF01138 RNase_PH, 3' exoribonuclease family. Contains PS01277 Ribonuclease PH signature.;UniProt_AC=P37939;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	837528	837674	.	+	0	Locus=ML0699A;Name=ML0699A;Function=;Product=deoA; hymidine phosphorylase(pseudogene);Comments=ML0699A, len:146. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1372844	1373224	.	-	0	Locus=ML1177c;Name=lprD;Function=;Product=PROBABLE CONSERVED LIPOPROTEIN LPRD;Comments=ML1177c, len: 126 aa. Probable lprD, conserved lipoprotein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD43_MYCLE (P54134) (126 aa), Fasta scores: E(): 0, 99.2% identity in 126 aa overlap. Also highly similar to Mycobacterium tuberculosis Rv1343c SW:YD43_MYCTU (Q11013) (126 aa), Fasta scores: E(): 0, 78.4% identity in 125 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=P54134;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1380642	1380944	.	-	0	Locus=ML1181c;Name=esxK2;Function=;Product=Putative ESAT-6 like protein EsxK2 ;Comments=ML1181c, len: 100 aa. Putative esxK2, ESAT-6 like protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein Q49945|U15180 (100 aa), Fasta scores: E(): 0, (100.0% identity in 100 aa overlap). Identical to ML1055 a possible orthologue of M. tuberculosis esxK. Also similar to several putative Esat-6 like proteins from M. tuberculosis e.g. O05299|ESXK_MYCTU ESAT-6 like protein esxK (98 aa), fasta scores: E(): 1.2e-19, (58.333% identity in 96 aa overlap). SEEMS TO BELONG TO THE ESAT6 FAMILY.;UniProt_AC=Q49945;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1395294	1396013	.	+	0	Locus=ML1190;Name=ML1190;Function=;Product=conserved hypothetical protein;Comments=ML1190, len: 239 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q9X7E1 (EMBL:AL049478) (239 aa), Fasta scores: E(): 0, 100.0% identity in 239 aa overlap. Also highly similar to Mycobacterium tuberculosis Rv2525c TR:P95028 (EMBL:Z83863) (240 aa), Fasta scores: E(): 0, 82.2% identity in 241 aa overlap.;UniProt_AC=Q9X7E1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1406366	1407694	.	+	0	Locus=ML1193;Name=ML1193;Function=;Product=conserved hypothetical protein;Comments=ML1193, len: 442 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q9X7E4 (EMBL:AL049478) (442 aa), Fasta scores: E(): 0, 100.0% identity in 442 aa overlap and highly similar to Mycobacterium tuberculosis hypothetical protein Rv2522c TR:O53227 (EMBL:AL021185) (470 aa), Fasta scores: E(): 0, 86.4% identity in 440 aa overlap. Contains Pfam match to entry PF01546 Peptidase_M20, Peptidase family M20/M25/M40.;UniProt_AC=Q9X7E4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1417756	1418682	.	+	0	Locus=ML1200;Name=ML1200;Function=;Product=possible pseudouridine synthase;Comments=ML1200, len: 308 aa. Possible pseudouridine synthase. Identical to the previously sequenced Mycobacterium leprae putative pseudouridine synthase TR:Q9X7E8 (EMBL:AL049478) (308 aa), Fasta scores: E(): 0, 99.7% identity in 308 aa overlap orthologues of which are known to be responsible for the synthesis pseudouridine from uracil within the 23s rRNA. Also highly similar to several others e.g. Mycobacterium tuberculosis Rv1540 SW:Y04P_MYCTU (Q10786) (308 aa), Fasta scores: E(): 0, 88.9% identity in 307 aa overlap and Escherichia coli SW:RLUD_ECOLI (P33643) (326 aa), Fasta scores: E(): 9.8e-23, 34.3% identity in 312 aa overlap. Contains Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase. Contains PS01129 Rlu family of pseudouridine synthase signature.;UniProt_AC=Q9X7E8;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1693104	1693607	.	+	0	Locus=ML1411;Name=argR;Function=;Product=Probable Arginine repressor ArgR (AHRC);Comments=ML1411, len: 167 aa. Probable argR, Arginine repressor. Highly similar to many ArgR orthologues (which regulate the arginine biosynthetic genes) including: Bacillus stearothermophilus SW:ARGR_BACST (O31408) (149 aa), Fasta scores: E(): 2.3e-10, 33.8% identity in 154 aa overlap and Mycobacterium tuberculosis Rv1657 SW:ARGR_MYCTU (P94992) (170 aa), Fasta scores: E(): 0, 79.7% identity in 158 aa overlap. Belongs to the argR family.;UniProt_AC=P57992;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1442505	1443542	.	+	0	Locus=ML1220;Name=bioB;Function=;Product=PROBABLE BIOTIN SYNTHETASE BIOB;Comments=ML1220, len: 345 aa. Probable bioB, biotin synthetase (EC 2.8.1.-). Identical to the previously sequenced Mycobacterium leprae biotin synthase SW:BIOB_MYCLE (P46715) (345 aa), Fasta scores: E(): 0, 99.1% identity in 345 aa overlap. Also highly similar to several others involved in biotin biosynthesis e.g. Escherichia coli SW:BIOB_ECOLI (P12996) (346 aa), Fasta scores: E(): 0, 35.3% identity in 309 aa overlap and Mycobacterium tuberculosis Rv1589 TR:BIOB_MYCTU (349 aa), fasta scores: E(): 5.9e-131, (87.106% identity in 349 aa overlap). Contains Pfam match to entry PF01792 Biotin_synth, Biotin synthase.;UniProt_AC=P46715;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1443807	1444403	.	+	0	Locus=ML1222;Name=ML1222;Function=;Product=CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML1222, len: 198 aa. Conserved transmembrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49626 (EMBL:U00010) (198 aa), Fasta scores: E(): 0, 99.5% identity in 198 aa overlap. Highly similar to proteins of undefined function also found downstream of BioB orthologues in Mycobacterium tuberculosis Rv1591 TR:O06599 (EMBL:Z95586) (221 aa), Fasta scores: E(): 0, 63.8% identity in 188 aa overlap and Mycobacterium bovis BCG TR:O52590 (EMBL:AF041819) (193 aa), Fasta scores: E(): 0, 67.6% identity in 170 aa overlap.;UniProt_AC=Q49626;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1449351	1450211	.	+	0	Locus=ML1227;Name=nadC;Function=;Product=Probable nicotinate-nucleotide pyrophosphatase NadC;Comments=ML1227, len: 286 aa. Probable nadC, nicotinate-nucleotide pyrophosphatas (EC 2.4.2.19). Identical to the previously sequenced Mycobacterium leprae nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) SW:NADC_MYCLE (P46714) (284 aa), Fasta scores: E(): 0, 100.0% identity in 284 aa overlap. Also highly similar several others from to Mycobacterium tuberculosis Rv1596 SW:NADC_MYCTU (O06594) (285 aa), Fasta scores: E(): 0, 79.2% identity in 283 aa overlap and Escherichia coli SW:NADC_ECOLI (P30011) (296 aa), Fasta scores: E(): 2.6e-32, 40.4% identity in 272 aa overlap. Contains Pfam match to entry PF01729 QRPTase, Quinolinate phosphoribosyl transferase.;UniProt_AC=P46714;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1454302	1460658	.	+	0	Locus=ML1229;Name=pks4;Function=;Product=PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4;Comments=ML1229, len: 2118 aa. Probable pks4, polyketide beta-ketoacyl synthase. Highly similar at the N-terminus to O50436|Rv1180 pks3 Beta-ketoacyl synthase from M. tuberculosis (488 aa), fasta scores: E(): 5.7e-150, (81.352% identity in 488 aa overlap) and in the C-terminus to O50437|Rv1181 pks4, Polyketide synthase from  M. tuberculosis (1582 aa), fasta scores: E(): 0, (75.326% identity in 1609 aa overlap). In M. tuberculosis pks3 and pks4 may represent separate modules of the polyketide synthase. Highly similar to many polyketide synthases involved in the biosynthesis of mycocerosyl lipids e.g. Mycobacterium tuberculosis probable mycocerosic acid synthase Rv2940c TR:P96291 (EMBL:Z83858) (2111 aa), Fasta scores: E(): 0, 60.8% identity in 2127 aa overlap and Mycobacterium bovis mycocerosic acid synthase SW:MCAS_MYCBO (Q02251) (2110 aa), Fasta scores: E(): 0, 58.8% identity in 2127 aa overlap. Highly similar to many other M. leprae polyketide synthases ML0101, ML0135, ML0139, ML2353, ML2354, ML2355, ML2356 and ML2357. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q49624;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	854541	854738	.	+	0	Locus=ML0714A;Name=ML0714A;Function=;Product=sulfatase family protein(pseudogene);Comments=ML0714A, len:197. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-07 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1465615	1466691	.	-	0	Locus=ML1232c;Name=ML1232c;Function=;Product=conserved hypothetical protein;Comments=ML1232c, len: 358 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49633 (EMBL:U00010) (391 aa), Fasta scores: E(): 0, 100.0% identity in 358 aa overlap. Also highly similar to Mycobacterium tuberculosis Possible exported protein Rv1184c TR:O50440 (EMBL:AL010186) (359 aa), Fasta scores: E(): 0, 62.7% identity in 338 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CC62;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1466856	1467548	.	-	0	Locus=ML1233c;Name=ML1233c;Function=;Product=conserved integral membrane protein;Comments=ML1233c, len: 230 aa. Conserved integral membrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein Q49630|U00010 (230 aa), Fasta scores: E(): 0, (100.0% identity in 230 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical protein Rv3821|O07802|Z97188 (237 aa), Fasta scores: E(): 2.9e-31, (46.7% identity in 240 aa overlap). Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q49630;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1503646	1504779	.	+	0	Locus=ML1258;Name=hisC;Function=;Product=Probable histidinol-phosphate aminotransferase 1 HisC (Imidazole acetol-phosphate transaminase 1);Comments=ML1258, len: 377 aa. Probable hisC, histidinol-phosphate aminotransferase 1 (EC 2.6.1.9). Highly similar to many histidinol-phosphate aminotransferases involved in histidine biosynthesis e.g. Mycobacterium tuberculosis Rv1600 TR:SW:HIS8_MYCTU (O06591) (380 aa), Fasta scores: E(): 0, 83.6% identity in 366 aa overlap and Mycobacterium smegmatis SW:HIS8_MYCSM (P28735) (219 aa), Fasta scores: E(): 0, 77.2% identity in 219 aa overlap. Contains Pfam match to entry PF00222 aminotran_2, Aminotransferases class-II. BELONGS TO CLASS-II OF PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES. HISTIDINOL-PHOSPHATE AMINOTRANSFERASES SUBFAMILY;UniProt_AC=Q9X7B8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1505405	1506025	.	+	0	Locus=ML1260;Name=hisH;Function=Histidine biosynthesis (fifth step). IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The hisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to hisF for the synthesis of IGP and AICAR. [CATALYTIC ACTIVITY: 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + L-glutamine = imidazole-glycerol phosphate + 5-aminoimidazol-4-carboxamide ribonucleotide + L-glutamate + H2O].;Product=Imidazole glycerol phosphate synthase subunit HisH (IGP synthase glutamine amidotransferase subunit) (IGP synthase subunit hisH) (ImGP synthase subunit hisH);Comments=ML1260, len: 206 aa. Probable hisH, Imidazole glycerol phosphate synthase subunit (EC 2.4.2.-). Highly similar to many amidotransferases involved in histidine biosynthesis including: Mycobacterium tuberculosis HisH (Rv1602) TR:O06589 (EMBL:Z95586) (206 aa), Fasta scores: E(): 0, 79.4% identity in 204 aa overlap and Escherichia coli SW:HIS5_ECOLI (P10375) (196 aa), Fasta scores: E(): 3.9e-20, 41.5% identity in 205 aa overlap. Contains Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I. Contains PS00442 Glutamine amidotransferases class-I active site. BELONGS TO THE HISH FAMILY.;UniProt_AC=Q9X7C0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1519221	1519661	.	+	0	Locus=ML1276;Name=ML1276;Function=;Product=conserved membrane protein;Comments=ML1276, len: 146 aa. Conserved membrane protein. Similar to several proteins of undefined function including: Mycobacterium tuberculosis Rv1616 TR:O06133 (EMBL:Z95554) (132 aa), Fasta scores: E(): 0, 68.5% identity in 127 aa overlap and Streptomyces coelicolor TR:Q9S2U5 (EMBL:AL096884) (148 aa), Fasta scores: E(): 5.3e-11, 41.4% identity in 128 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CC50;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1516635	1517447	.	+	0	Locus=ML1273;Name=trpA;Function=tryptophan biosynthesis pathway (fifth - last step). THE ALPHA SUBUNIT IS RESPONSIBLE FOR THE ALDOL CLEAVAGE OF INDOLEGLYCEROL PHOSPHATE TO INDOLE AND GLYCERALDEHYDE 3- PHOSPHATE. [CATALYTIC ACTIVITY: L-SERINE + 1-(INDOL-3-YL)GLYCEROL 3-PHOSPHATE = L-TRYPTOPHAN + GLYCERALDEHYDE 3-PHOSPHATE + H(2)O.];Product=Probable tryptophan synthase, alpha subunit TrpA;Comments=ML1273, len: 270 aa. Probable trpA, tryptophan synthase, alpha subunit (EC 4.2.1.20). Highly similar to many tryptophan synthases [alpha chain] involved in tryptophan biosynthesis e.g. Mycobacterium tuberculosis Rv1613 SW:TRPA_MYCTU (O06130) (270 aa), Fasta scores: E(): 0, 86.0% identity in 265 aa overlap and Streptomyces coelicolor SW:TRPA_STRCO (O68816) (271 aa), Fasta scores: E(): 0, 46.4% identity in 261 aa overlap. Contains Pfam match to entry PF00290 trp_syntA, Tryptophan synthase alpha chain. Belongs to the trpA family. ;UniProt_AC=Q9CC53;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1515385	1516638	.	+	0	Locus=ML1272;Name=trpB;Function=tryptophan biosynthesis pathway (fifth last step). THE BETA SUBUNIT IS RESPONSIBLE FOR THE SYNTHESIS OF L-TRYPTOPHAN FROM INDOLE AND L-SERINE. [CATALYTIC ACTIVITY : L-SERINE + 1-(INDOL-3-YL)GLYCEROL 3-PHOSPHATE = L-TRYPTOPHAN + GLYCERALDEHYDE 3-PHOSPHATE + H(2)O];Product=Probable tryptophan synthase, beta subunit TrpB;Comments=ML1272, len: 417 aa. Probable trpB, tryptophan synthase, beta subunit (EC 4.2.1.20). Highly similar to many tryptophan synthases [beta chain] involved in tryptophan biosynthesis e.g. Mycobacterium tuberculosis Rv1612 SW:TRPB_MYCTU (O08376) (410 aa), Fasta scores: E(): 0, 86.7% identity in 407 aa overlap and Streptomyces coelicolor SW:TRPB_STRCO (O05625) (427 aa), Fasta scores: E(): 0, 65.2% identity in 405 aa overlap. Contains Pfam match to entry PF00291 S_T_dehydratase, Pyridoxal-phosphate dependent enzyme. Contains PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site.;UniProt_AC=Q9CC54;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1514503	1515321	.	+	0	Locus=ML1271;Name=trpC;Function=;Product=Probable indole-3-glycerol phosphate synthase TrpC;Comments=ML1271, len: 272 aa. Probable trpC, indole-3-glycerol phosphate synthase (EC 4.1.1.48). Highly similar to many indole-3-glycerol phosphate synthases involved in tryptophan biosynthesis e.g. Mycobacterium tuberculosis Rv1611 SW:TRPC_MYCTU (O06129) (272 aa), Fasta scores: E(): 0, 90.8% identity in 272 aa overlap and Streptomyces coelicolor SW:TRC1_STRCO (O68814) (269 aa), Fasta scores: E(): 0, 64.1% identity in 262 aa overlap. Contains Pfam match to entry PF00218 IGPS, Indole-3-glycerol phosphate synthases. Contains PS00614 Indole-3-glycerol phosphate synthase signature.;UniProt_AC=Q9X7C7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1733643	1734476	.	-	0	Locus=ML1440c;Name=ppm1a;Function=;Product=Polyprenol-monophosphomannose synthase Ppm1a;Comments=ML1440c, len: 277 aa. Probable ppm1a, Polyprenol-monophosphomannose synthase. Highly similar to C-terminus of a Polyprenol-monophosphomannose synthase from Mycobacterium tuberculosis Rv2051c TR:O53493 (EMBL:AL021899) (874 aa), Fasta scores: E(): 0, 78.9% identity in 275 aa overlap. Homology to Rv2051c continues downstream of this ORF in a different frame suggesting a possible frameshift. Also similar to other glycosyl transferases e.g. Q827K1 Putative glycosyl transferase from Streptomyces avermitilis (265 aa), fasta scores: E(): 1.3e-57, (56.274% identity in 263 aa overlap). Contains Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferases.;UniProt_AC=O32929;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1555823	1556647	.	-	0	Locus=ML1306c;Name=ML1306c;Function=;Product=conserved hypothetical protein;Comments=ML1306c, len: 274 aa. Conserved hypothetical protein. Similar to several proteins of unknown function including: Mycobacterium tuberculosis Rv2125 TR:O33260 (EMBL:Z97559) (292 aa), Fasta scores: E(): 0, 85.0% identity in 274 aa overlap and Streptomyces coelicolor TR:Q9S2K6 (EMBL:AL109732) (312 aa), Fasta scores: E(): 1.6e-07, 23.4% identity in 278 aa overlap.;UniProt_AC=Q9CC38;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1036452	1037426	.	+	0	Locus=ML0873;Name=adk;Function=;Product=Probable adenosine kinase adk;Comments=ML0873, len: 324 aa. Probable adk, adenosine kinase (EC 2.7.1.20). Similar to Mycobacterium tuberculosis adk, adenosine kinase Rv2202c or MTCY190.13C SW:YM02_MYCTU (Q10391) (324 aa) fasta scores: E(): 0, 83.3% identity in 324 aa, and to Streptomyces coelicolor putative kinase SC6G10.31C TR:Q9X816 (EMBL:AL049497) (338 aa) fasta scores: E(): 0, 58.9% id in 319 aa. Shows weak similarity to known kinases e.g. Bacillus subtilis ribokinase rbsK SW:RBSK_BACSU (P36945; P96733) (293 aa) fasta scores: E(): 1.2e-07, 26.1% identity in 283 aa. Contains Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase. Contains PS00583 pfkB family of carbohydrate kinases signature 1. Belongs to the carbohydrate kinase pfkB family. Previously known as cbhK.;UniProt_AC=Q9CCF3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1416025	1416957	.	-	0	Locus=ML1198c;Name=ansA;Function=;Product=Probable L-aparaginase AnsA;Comments=ML1198c, len: 310 aa. Probable L-asparaginase (EC 3.5.1.1). Identical to the previously sequenced Mycobacterium leprae probable L-asparaginase SW:ASPG_MYCLE (Q9X7E6) (310 aa), Fasta scores: E(): 0, 100.0% identity in 310 aa overlap. Also highly similar to many other L-asparaginases e.g. Mycobacterium tuberculosis Rv1538c SW:ASPG_MYCTU (Q10759) (315 aa), Fasta scores: E(): 0, 72.4% identity in 315 aa overlap and Saccharomyces cerevisiae SW:ASG1_YEAST (P38986) (381 aa), Fasta scores: E(): 6.4e-12, 27.5% identity in 327 aa overlap. Also similar to ML2343 a possible pseudogene similar to M. tuberculosis ansA. Contains Pfam match to entry PF00710 Asparaginase, Asparaginase. Contains PS00917 Asparaginase / glutaminase active site signature 2. Contains PS00144 Asparaginase / glutaminase active site signature 1. Belongs to the asparaginase 1 family.;UniProt_AC=Q9X7E6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1061590	1062978	.	+	0	Locus=ML0896;Name=aroG;Function=;Product=Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phenylalanine-repressible);Comments=ML0896, len: 462 aa.  Probable aroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (EC 4.1.2.15). Highly similar to many others e.g. Mycobacterium tuberculosis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase TR:O53512 (EMBL:AL021957) (462 aa), Fasta scores: E(): 0, 89.7% identity in 465 aa overlap; and similar to many plant DAHP synthetase family proteins e.g. Arabidopsis thaliana SW:AROF_ARATH (SW:P29976) (525 aa), Fasta scores: E(): 0, 49.0% identity in 441 aa overlap. Identical to the previously sequenced Mycobacterium leprae 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase TR:O69569 (EMBL:AL022602) (462 aa), Fasta scores: E(): 0, 100.0% identity in 462 aa overlap. Contains Pfam match to entry PF01474 DAHP_synth_2, Class-II DAHP synthetase family.;UniProt_AC=O69569;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1510443	1511537	.	+	0	Locus=ML1267;Name=chaA;Function=;Product=Probable ionic transporter integral membrane protein ChaA;Comments=ML1267, len: 364 aa. Probable chaA, ionic transporter integral membrane protein, putative calcium/proton antiporter. Highly similar to many antiporters e.g. Mycobacterium tuberculosis Rv1607 TR:O53910 (EMBL:AL022001) (360 aa), Fasta scores: E(): 0, 77.7% identity in 364 aa overlap and Escherichia coli SW:CHAA_ECOLI (P31801) (366 aa), Fasta scores: E(): 0, 36.5% identity in 356 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9X7C4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	902906	903093	.	-	0	Locus=ML0759A;Name=ML0759A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0759A, len:187. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-17 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1335155	1336051	.	+	0	Locus=ML1144;Name=atpG;Function=;Product=PROBABLE ATP SYNTHASE GAMMA CHAIN ATPG;Comments=ML1144, len: 298 aa. Probable atpG, ATP synthase [gamma] chain (EC 3.6.3.14). Identical to the previously sequenced Mycobacterium leprae ATP synthase gamma chain (EC 3.6.1.34) SW:ATPG_MYCLE (P45824) (298 aa), Fasta scores: E(): 0, 100.0% identity in 298 aa overlap. Also highly similar to many other proposed ATPase gamma chain family proteins e.g. Mycobacterium tuberculosis Rv1309 SW:ATPG_MYCTU (Q10597) (305 aa), Fasta scores: E(): 0, 83.9% identity in 305 aa overlap and Streptomyces lividans SW:ATPG_STRLI (P50007) (302 aa), Fasta scores: E(): 0, 48.2% identity in 301 aa overlap. Contains Pfam match to entry PF00231 ATP-synt, ATP synthase. Contains PS00153 ATP synthase gamma subunit signature.;UniProt_AC=P45824;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1438600	1439910	.	+	0	Locus=ML1216;Name=bioA;Function=;Product=PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA;Comments=ML1216, len: 436 aa. Probable bioA, adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62). Identical to the previously sequenced Mycobacterium leprae adenosylmethionine-8-amino-7-oxononanoate SW:BIOA_MYCLE (P45488) (436 aa), Fasta scores: E(): 0, 100.0% identity in 436 aa overlap. Also highly similar to other proteins which have been shown to be involved in the biosynthesis of biotin e.g. Escherichia coli SW:BIOA_ECOLI (P12995) (429 aa), Fasta scores: E(): 0, 50.0% identity in 418 aa overlap BioA and Mycobacterium tuberculosis Rv1568 SW:BIOA_MYCTU (O06622) (437 aa), Fasta scores: E(): 0, 85.1% identity in 436 aa overlap, BioA. Contains Pfam match to entry PF00202 aminotran_3, Aminotransferases class-III pyridoxal-phosphate. Contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.;UniProt_AC=P45488;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1000554	1001789	.	+	0	Locus=ML0842;Name=csd1;Function=;Product=Probable cysteine desulfurase 1 Csd1;Comments=ML0842, len: 411 aa. csd1, probable cysteine desulfurase 1 (EC 4.4.1.-). Highly similar to the carboxy region of Q9KII6|CSD_MYCPA Probable cysteine desulfurase from Mycobacterium paratuberculosis (685 aa), fasta scores: E(): 8.7e-152, (85.086% identity  in 409 aa overlap); and similar to Rv1464|MTV007.11|O53155|AL021184 csd probable cysteine desulfurase from Mycobacterium tuberculosis  (417 aa), fasta scores: E(): 0, (43.6% identity in 408 aa). Also similar to ML0117, ML0596 and ML1708 from M. leprae. Previously sequenced as O32975|Z98741. Contains Pfam match to entry PF00266 aminotran_5, Aminotransferases class-V. Belongs to the class-V of pyridoxal-phosphate-dependent aminotransferases. Csd subfamily.;UniProt_AC=O32975;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1046922	1047530	.	-	0	Locus=ML0882c;Name=ctaE;Function=;Product=PROBABLE CYTOCHROME C OXIDASE (SUBUNIT III) CTAE;Comments=ML0882c, len: 202 aa. Probable ctaE, cytochrome c oxidase polypeptide III (cox3) (EC 1.9.3.1)Similar to Mycobacterium tuberculosis probable cytochrome C oxidase polypeptide III ctaE or Rv2193 or MTCY190.04 SW:COX3_MYCTU (Q10385) (203 aa) fasta scores: E(): 0, 90.1% identity in 203 aa. Similar to many e.g. Synechococcus vulcanus cytochrome C oxidase polypeptide III ctaE SW:COX3_SYNVU (P50677) (201 aa) fasta scores: E(): 1.2e-23, 39.0% identity in 200 aa. Previously sequenced as TR:O69582 (EMBL:AL022602). Contains hydrophobic, probable membrane-spanning regions. Contains Pfam match to entry PF00510 COX3, Cytochrome c oxidase subunit III. Belongs to the cytochrome c oxidase subunit 3 family.;UniProt_AC=O69582;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	995673	996356	.	-	0	Locus=ML0838c;Name=cysE;Function=;Product=PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT);Comments=ML0838c, len: 227 aa. Probable cysE, serine acetyltransferase (EC 2.3.1.30). Similar to Mycobacterium tuberculosis putative serine acetyltransferase cysE or Rv2335 or MTCY98.0031c TR:P95231 (EMBL:Z83860) (229 aa) fasta scores: E(): 0, 76.4% identity in 229 aa, and to Bacillus subtilis serine acetyltransferase cysE or cysA SW:CYSE_BACSU (Q06750) (217 aa) fasta scores: E(): 0, 47.1% identity in 204 aa. Previously sequenced as TR:O32979 (EMBL:Z98741). Contains 4 Pfam matches to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats). Contains PS00101 Hexapeptide-repeat containing-transferases signature. BELONGS TO THE CYSE/LACA/LPXA/NODL FAMILY OF ACETYLTRANSFERASES. COMPOSED OF MULTIPLE REPEATS OF [LIV]-G-X(4);UniProt_AC=O32979;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1223703	1224767	.	+	0	Locus=ML1059;Name=dapE;Function=;Product=PROBABLE SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE DAPE;Comments=ML1059, len: 354 aa. Probable dapE, succinyl-diaminopimelate desuccinylase (EC 3.5.1.18). Identical to the previously sequenced Mycobacterium leprae TR:Q49949 (EMBL:U15180) (400 aa), Fasta scores: E(): 0, 100.0% identity in 354 aa overlap. Also highly similar to succinyl-diaminopimelate desuccinylases from Mycobacterium tuberculosis Rv1202 TR:O05303 (EMBL:Z93777) (354 aa), Fasta scores: E(): 0, 86.7% identity in 354 aa overlap and Corynebacterium glutamicum SW:DAPE_CORG (Q59284) (369 aa), Fasta scores: E(): 0, 56.3% identity in 359 aa overlap. Contains Pfam match to entry PF01546 Peptidase_M20, Peptidase family M20/M25/M40. Contains PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.;UniProt_AC=Q9CCB0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1423017	1426550	.	+	0	Locus=ML1207;Name=dnaE;Function=DNA POLYMERASE III IS A COMPLEX, MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THIS DNA POLYMERASE ALSO EXHIBITS 3' TO 5' EXONUCLEASE ACTIVITY. THE ALPHA CHAIN IS THE DNA POLYMERASE [CATALYTIC ACTIVITY : N DEOXYNUCLEOSIDE TRIPHOSPHATE = N DIPHOSPHATE + {DNA}(N)].;Product=PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE);Comments=ML1207, len: 1177 aa. Probable dnaE1, DNA polymerase III, alpha chain (EC 2.7.7.7). Identical to the previously sequenced Mycobacterium leprae putative DNA polymerase III alpha chain TR:Q9X7F0 (EMBL:AL049478) (1177 aa), Fasta scores: E(): 0, 100.0% identity in 1177 aa overlap. Also highly similar to DNA polymerases from e.g. Mycobacterium tuberculosis Rv1547 SW:DP3A_MYCTU (Q10779) (1184 aa), Fasta scores: E(): 0, 91.2% identity in 1176 aa overlap and Escherichia coli DnaE or PolC SW:DP3A_ECOLI (P10443) (1160 aa), Fasta scores: E(): 0, 36.1% identity in 1193 aa overlap. Contains Pfam match to entry PF02193 POLIIIAc, DNA polymerase alpha chain like domain. BELONGS TO DNA POLYMERASE TYPE-C FAMILY,  DNAE SUBFAMILY;UniProt_AC=Q9X7F0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1476554	1477438	.	+	0	Locus=ML1241;Name=echA12;Function=;Product=possible enoyl-CoA hydratase/isomerase EchA12 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE) ;Comments=ML1241, len: 294 aa. Possible enoyl-CoA hydratase (EC 4.2.1.17). Highly similar to ECHC_MYCTU|O53163|Rv1472 EchA12 probable enoyl-CoA hydratase from Mycobacterium tuberculosis (285 aa), Fasta scores: E(): 0, (72.0% identity in 271 aa overlap) and CRT_CLOAB|P52046 acetobutylicum 3-hydroxybutyryl-CoA dehydratase from Clostridium  (EC 4.2.1.55)  (261 aa), Fasta scores: E(): 5.1e-18, (31.1% identity in 264 aa overlap). Also similar to ML1817c a possible pseudogene similar to M. tuberculosis echA12. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family. Contains PS00166 Enoyl-CoA hydratase/isomerase signature.;UniProt_AC=P53526;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	933379	933450	.	-	0	Locus=ML0789A;Name=ML0789A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0789A, len:71. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-48 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1380303	1380590	.	-	0	Locus=ML1180c;Name=esxL2;Function=;Product=Putative ESAT-6 like protein EsxL2 (ESAT-6 LIKE PROTEIN 4);Comments=ML1180c, len: 95 aa. Probable esxL2, ESAT-6 like protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein Q49946|EMBL:U15180 (95 aa), Fasta scores: E(): 0, (100.0% identity in 95 aa overlap). Identical to ML1056 a possible orthologue of M. tuberculosis esxL1. Also similar to several putative Esat-6 like proteins from M. tuberculosis e.g. O05300|ESXL_MYCTU ESAT-6 like protein esxL (94 aa), Fasta scores: E(): 7.7e-24, (64.130% identity in 92 aa overlap). SEEMS TO BELONG TO THE ESAT6 FAMILY.;UniProt_AC=Q49946;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1631874	1633262	.	+	0	Locus=ML1372;Name=engA;Function=;Product=PROBABLE GTP-BINDING PROTEIN ENGA;Comments=ML1372, len: 462 aa. Probable engA, GTP-binding protein. Highly similar to many proposed Era/ThdF family GTP-binding proteins including: Bacillus subtilis SW:ENGA_BACSU (P50743) (436 aa), Fasta scores: E(): 0, 41.0% identity in 434 aa overlap and Mycobacterium tuberculosis Rv1713 SW:ENGA_MYCTU (O33212) (463 aa), Fasta scores: E(): 0, 88.6% identity in 463 aa overlap. Contains Pfam match to entry PF01926 MMR_HSR1, GTPase of unknown function. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q49884;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1352915	1354096	.	+	0	Locus=ML1158;Name=fadA4;Function=;Product=PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA4 (ACETOACETYL-CoA THIOLASE);Comments=ML1158, len: 393 aa. Probable fadA4, acetyl-CoA C-acetyltransferase (EC 2.3.1.9). Identical to the previously sequenced Mycobacterium leprae probable acetyl-CoA acetyltransferase SW:THIL_MYCLE (P46707) (393 aa), Fasta scores: E(): 0, 100.0% identity in 393 aa overlap. Also highly similar to many others including: Mycobacterium tuberculosis (FadA4) Rv1323 SW:THIL_MYCTU (Q10629) (389 aa), Fasta scores: E(): 0, 86.9% identity in 388 aa overlap and acetyl-CoA acetyltransferases from Alcaligenes eutrophus SW:THIL_ALCEU (P14611) (393 aa), Fasta scores: E(): 0, 50.4% identity in 389 aa overlap. Also similar to ML2162 from M. leprae. Contains Pfam match to entry PF00108 thiolase, Thiolase. Contains PS00098 Thiolases acyl-enzyme intermediate signature. Contains PS00099 Thiolases active site. Contains PS00737 Thiolases signature 2.;UniProt_AC=P46707;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1506035	1506772	.	+	0	Locus=ML1261;Name=hisA;Function=histidine biosynthesis pathway (fourth step) [CATALYTIC ACTIVITY : 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide = 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide..];Product=PROBABLE PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDE ISOMERASE HISA (1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase);Comments=ML1261, len: 245 aa. Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16).  Highly similar to many phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerases involved in histidine biosynthesis including: Mycobacterium tuberculosis Rv1603 SW:HIS4_MYCT (O0658) (245 aa), Fasta scores: E(): 0, 84.4% identity in 244 aa overlap and Streptomyces coelicolor SW:HIS4_STRCO (P16250) (240 aa), Fasta scores: E(): 0, 66.3% identity in 240 aa overlap. Contains Pfam match to entry PF00977 His_biosynth, Histidine biosynthesis protein. Belongs to the hisA / hisF family. ;UniProt_AC=Q9CC56;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1326904	1327770	.	+	0	Locus=ML1135;Name=hemK;Function=;Product=PROBABLE PROTOPORHYRINOGEN OXIDASE HEMK HOMOLOG;Comments=ML1135, len: 288 aa. Probable hemK, protoporphyrinogen oxidase. Highly similar to numerous members of the HemK family of modification methylases such as Mycobacterium tuberculosis, Rv1300, SW:HEMK_MYCTU (Q10602) (325 aa), Fasta scores: E(): 0, 73.9% identity in 284 aa overlap and Escherichia coli SW:HEMK_ECOLI (P37186) (277 aa), Fasta scores: E(): 2.4e-17, 32.5% identity in 277 aa overlap.;UniProt_AC=P45832;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1467578	1469317	.	-	0	Locus=ML1234c;Name=fadD21;Function=;Product=PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE);Comments=ML1234c, len: 579 aa. Probable fadD21, fatty-acid-CoA synthetase (EC 6.2.1.-). Highly similar to acyl-CoA synthases from Mycobacterium tuberculosis Rv1185c TR:O50441 (EMBL:AL010186) (578 aa), Fasta scores: E(): 0, 72.4% identity in 579 aa overlap and Mycobacterium bovis TR:P71495 (EMBL:U7568) (582 aa), Fasta scores: E(): 0, 63.4% identity in 579 aa overlap. Also similar to ML0100, ML0132, ML0138, ML0243 and ML2358 from M. leprae. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme.;UniProt_AC=P54200;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1217112	1218542	.	+	0	Locus=ML1051;Name=fadD36;Function=;Product=PROBABLE FATTY-ACID-CoA LIGASE FADD36 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE);Comments=ML1051, len: 476 aa. Probable fadD36, fatty-acid-CoA synthetase (EC 6.2.1.-). Identical to the previously sequenced Mycobacterium leprae XclC TR:Q50017 (EMBL:U15181) (476 aa), Fasta scores: E(): 0, 99.8% identity in 476 aa overlap. Also highly similar to many others including: Mycobacterium tuberculosis fatty-acid-CoA synthetase Rv1193 fadD36 TR:O05295 (EMBL:Z93777) (473 aa), Fasta scores: E(): 0, 81.3% identity in 476 aa overlap and Escherichia coli long-chain-fatty-acid--coa ligase (EC 6.2.1.3) SW:LCFA_ECOLI (P29212) (561 aa), Fasta scores: E(): 1.3e-28, 31.7% identity in 378 aa overlap. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature. Contains PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. BELONGS TO THE ATP-DEPENDENT AMP-BINDING ENZYME FAMILY. Note previously known as xclC;UniProt_AC=Q50017;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1144499	1147159	.	+	0	Locus=ML0977;Name=ftsK;Function=;Product=POSSIBLE CELL DIVISION TRANSMEMBRANE PROTEIN FTSK;Comments=ML0977, len: 886 aa. Probable Cell division transmembrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O05560 (EMBL:Z94723) (886 aa), Fasta scores: E(): 0, 100.0% identity in 886 aa overlap. Also highly similar to many proteins involved in cell division e.g. Escherichia coli SW:FTSK_ECOLI (P46889) (1329 aa), Fasta scores: E(): 0, 43.9% identity in 531 aa overlap and Mycobacterium tuberculosis Rv2748c TR:O33290 (EMBL:AL008967) (883 aa), Fasta scores: E(): 0, 78.1% identity in 885 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01580 FtsK_SpoIIIE, FtsK/SpoIIIE family. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE FTSK/SPOIIIE FAMILY.;UniProt_AC=O05560;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	962710	963297	.	-	0	Locus=ML0813c;Name=ML0813c;Function=;Product=possible membrane protein;Comments=ML0813c, len: 195 aa. Possible membrane protein. Similar to Rv3209|MTCY07D11.17c|O05857|Z95120 Mycobacterium tuberculosis Conserved hypothetical thr-, pro-rich protein (186 aa), fasta scores: E(): 8.5e-23, (58.4% identity in 185 aa) and to Rv2198c|MTCY190.09c|MMS3_MYCTU|Q10390 Mycobacterium tuberculosis putative membrane protein mmpS3 (299 aa) fasta scores: E(): 9.4e-08, 31.0% identity in 203 aa. Also similar to ML0431 and ML0877 from M. leprae. Contains N-terminal hydrophobic region.;UniProt_AC=Q9CCH2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	978844	980235	.	+	0	Locus=ML0826;Name=glyS;Function=;Product=PROBABLE GLYCYL-tRNA SYNTHETASE GLYS (GLYCINE--tRNA LIGASE) (GLYRS);Comments=ML0826, len: 463 aa. Probable glyS, glycyl-tRNA synthetase (EC 6.1.1.14). Similar to Rv2357c|MTCY27.23|MTCY98.26|SYG_MYCTU|O65932 Mycobacterium tuberculosis glycyl-tRNA synthetase glyS  (463 aa) fasta scores: E(): 0, 90.2% identity in 459 aa and to SYG_THETH|P56206 Thermus aquaticus glycyl-tRNA synthetase glyS (505 aa) fasta scores: E(): 0, 43.6% identity in 512 aa. Contains Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II (G, H, P, S and T). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. BELONGS TO CLASS-II AMINOACYL-TRNA SYNTHETASE FAMILY.;UniProt_AC=Q9CCG4;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1240775	1242376	.	+	0	Locus=ML1078;Name=htrA;Function=;Product=PROBABLE SERINE PROTEASE HTRA (DEGP PROTEIN);Comments=ML1078, len: 533 aa. Probable htrA, serine protease (EC 3.4.21.-). Identical to the previously sequenced Mycobacterium leprae TR:Q49972 (EMBL:U15180) (533 aa), Fasta scores: E(): 0, 99.8% identity in 533 aa overlap. Also highly similar to Mycobacterium tuberculosis possible serine protease HtrA Rv1223 TR:O06291 (EMBL:Z98260) (528 aa), Fasta scores: E(): 0, 81.8% identity in 533 aa overlap. The C-terminus of this CDS is similar to several proven proteases e.g. Escherichia coli SW:HTRA_ECOLI (P09376) (474 aa), Fasta scores: E(): 2e-26, 35.3% identity in 283 aa overlap. Contains a possible membrane spanning hydrophobic domain. Contains Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF). Contains Pfam match to entry PF00089 trypsin, Trypsin. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q49972;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	963831	964517	.	-	0	Locus=ML0815c;Name=ML0815c;Function=;Product=PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY);Comments=ML0815c, len: 228 aa. Probable transcriptional regulator, TetR family. Similar to Rv3208|MTCY07D11.18c|O05858|Z95120 Mycobacterium tuberculosis putative TetR-family transcriptional regulator (228 aa)  fasta scores: E(): 0, (82.4% identity in 227 aa). Contains a probable helix-turn-helix motif at aa 60-81 (Score 1517, SD +4.35) Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family. SIMILAR TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS.;UniProt_AC=Q9CCH0;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1021413	1022120	.	-	0	Locus=ML0859c;Name=lipB;Function=;Product=Probable lipoate biosynthesis protein B LipB;Comments=ML0859c, len: 235 aa. Probable lipB, lipoate-protein ligase B (EC. 6.-.-.-). Similar to Mycobacterium tuberculosis lipoate-protein ligase B lipB or Rv2217 or MTCY190.28 SW:LIPB_MYCTU (Q10404) (230 aa) fasta scores: E(): 0, 78.4% identity in 218 aa. Similar to Escherichia coli lipoate-protein ligase B lipB SW:LIPB_ECOLI (P30976) (191 aa) blastp scores:: 84.1 bits, 55% identity in 163 aa. Previously sequenced as SW:LIPB_MYCLE (O32961). Contains Pfam match to entry PF02111 Lipoate_B, Lipoate-protein ligase B. Contains PS01313 Lipoate-protein ligase B signature.;UniProt_AC=O32961;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1068514	1069233	.	-	0	Locus=ML0902c;Name=lppM;Function=;Product=probable conserved lipoprotein LppM;Comments=ML0902c, len: 239 aa. Probable lppM, conserved lipoprotein. Identical to the previously sequenced Mycobacterium leprae putative lipoprotein TR:O69564 (EMBL:AL022602) (239 aa), Fasta scores: E(): 0, 99.6% identity in 239 aa overlap and also highly similar to another putative lipoprotein from Mycobacterium tuberculosis TR:O53505 (EMBL:AL021957) (227 aa), Fasta scores: E(): 0, 75.4% identity in 224 aa overlap. Contains a possible N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=O69564;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1234640	1235293	.	+	0	Locus=ML1070;Name=ML1070;Function=;Product=possible TetR-family transcriptional regulatory protein;Comments=ML1070, len: 217 aa. Possible TetR-family transcriptional regulatory protein. Identical to the previously sequenced Mycobacterium leprae Q49962|U15180 (217 aa), Fasta scores: E(): 0, (100.0% identity in 217 aa overlap). Also similar to many transcriptional regulatory proteins and appears to be a paralogue of Rv3855|P96222|Z83864 ethR regulatory protein tetR family from M. tuberculosis (216 aa), Fasta scores: E(): 0, (60.4% identity in 202 aa overlap). Also similar to ML0064 ethR regulatory protein from M. leprae. Contains a probable helix-turn-helix motif at aa 49-70 (Score 1321, SD +3.69). Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family.;UniProt_AC=Q49962;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1248328	1249734	.	+	0	Locus=ML1086;Name=lpqY;Function=;Product=PROBABLE SUGAR-BINDING LIPOPROTEIN LPQY;Comments=ML1086, len: 468 aa. Probable lpqY, sugar-binding lipoprotein component of sugar transport system. Previously sequenced Mycobacterium leprae TR:Q49975 (EMBL:U15180) (469 aa), Fasta scores: E(): 0, 100.0% identity in 468 aa overlap. Also similar to many solute-binding transport proteins e.g. from Mycobacterium tuberculosis Rv1235 TR:O31095 (EMBL:AF028830) (468 aa), Fasta scores: E(): 0, 77.6% identity in 469 aa overlap and Escherichia coli SW:MALE_ECOLI (P02928) (396 aa), Fasta scores: E(): 0.00081, 23.4% identity in 295 aa overlap. Contains a possible N-terminal signal sequence  and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CCA3;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1291566	1292132	.	+	0	Locus=ML1115;Name=lprB;Function=;Product=POSSIBLE LIPOPROTEIN LPRB;Comments=ML1115, len: 188 aa. Possible lprB, lipoprotein. Highly similar to Mycobacterium tuberculosis possible lipoprotein Rv1274 SW:LPRB_MYCTU (Q11045) (185 aa), Fasta scores: E(): 0, 78.2% identity in 188 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CC87;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1270160	1270768	.	-	0	Locus=ML1099c;Name=lprE;Function=;Product=PROBABLE LIPOPROTEIN LPRE;Comments=ML1099c, len: 202 aa. Probable lprE lipoprotein. Highly similar to Mycobacterium tuberculosis putative lipoprotein SW:LPRE_MYCTU (Q11065) (202 aa), Fasta scores: E(): 0, 71.3% identity in 202 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CC94;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1318223	1319641	.	+	0	Locus=ML1128;Name=lysA;Function=;Product=PROBABLE DIAMINOPIMELATE DECARBOXYLASE LYSA (DAP DECARBOXYLASE);Comments=ML1128, len: 472 aa. Probable lysA, diaminopimelate decarboxylase (EC 4.1.1.20). Previously sequenced Mycobacterium leprae Q50140|U15186 (495 aa), Fasta scores: E(): 0, 100.0% identity in 472 aa overlap. Highly similar to many diaminopimelate decarboxylases (EC 4.1.1.20) involved in the last step of lysine biosynthesis e.g. DCDA_MYCTU|P31848 Rv1293 LysA from Mycobacterium tuberculosis (447 aa), Fasta scores: E(): 0, (86.8% identity in 446 aa overlap). Also similar to ML0251c a possible pseudogene similar to M. tuberculosis lysA. Contains Pfam match to entry PF00750 tRNA-synt_1d, tRNA synthetases class I (R). Contains Pfam match to entry PF00278 Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase. Contains PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site.;UniProt_AC=Q50140;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1259135	1259968	.	-	0	Locus=ML1094c;Name=ML1094c;Function=;Product=ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE;Comments=ML1094c, len: 277 aa. Probable short-chain dehydrogenase/reductase (EC 1.-.-.-). Highly similar to several Mycobacterium tuberculosis putative oxidoreductases e.g. Rv1245c TR:O50460 (EMBL:AL021006) (276 aa), Fasta scores: E(): 0, 78.3% identity in 277 aa overlap. Also similar to many others including: Pseudomonas paucimobilis SW:LINX_PSEPA (P50198) (250 aa), Fasta scores: E(): 9.3e-17, 35.6% identity in 194 aa overlap 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature.;UniProt_AC=Q9CC98;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1058708	1059994	.	-	0	Locus=ML0893c;Name=ML0893c;Function=;Product=probable conserved integral membrane protein;Comments=ML0893c, len: 428 aa. Probable conserved integral membrane protein. Identical to the previously sequenced Mycobacterium leprae putative integral membrane protein TR:O69571 (EMBL:AL022602) (428 aa), Fasta scores: E(): 0, 100.0% identity in 428 aa overlap. Also highly similar to Mycobacterium tuberculosis putative membrane protein Rv2181 TR:O53515 (EMBL:AL021957) (427 aa), Fasta scores: E(): 0, 80.0% identity in 431 aa overlap. Contains multiple possible membrane spanning hydrophobic domains and a possible N-terminal signal sequence.;UniProt_AC=O69571;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1070254	1070658	.	+	0	Locus=ML0904;Name=ML0904;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML0904, len: 134 aa. Probable conserved membrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69562 (EMBL:AL022602) (134 aa), Fasta scores: E(): 0, 100.0% identity in 134 aa overlap. Also highly similar to several others e.g. Mycobacterium tuberculosis hypothetical protein Rv2169c TR:O53503 (EMBL:AL021957) (134 aa), Fasta scores: E(): 0, 86.6% identity in 134 aa overlap and Streptomyces coelicolor putative membrane protein TR:Q9XAJ8 (EMBL:AL079348) (96 aa), Fasta scores: E(): 0.22, 38.3% identity in 60 aa overlap. Contains a large central possible membrane spanning hydrophobic domain.;UniProt_AC=O69562;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1147778	1148359	.	+	0	Locus=ML0979;Name=pgsA3;Function=;Product=PROBABLE PGP SYNTHASE PGSA3 (CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3- PHOSPHATIDYLTRANSFERASE) (PHOSPHATIDYLGLYCEROPHOSPHATE SYNTHASE);Comments=ML0979, len: 193 aa. Probable pgsA3, PGP synthase (EC 2.7.8.5). Identical to the previously sequenced Mycobacterium leprae TR:Q49839 (EMBL:U00019) (193 aa), Fasta scores: E(): 0, 100.0% identity in 193 aa overlap. Also highly similar to many phosphatidylglycerophosphate synthases including: Mycobacterium tuberculosis Rv2746c TR:O33288 (EMBL:AL008967) (209 aa), Fasta scores: E(): 0, 77.1% identity in 188 aa overlap and Bacillus subtilis SW:PGSA_BACSU (P46322) (193 aa), Fasta scores: E(): 5.6e-17, 35.8% identity in 193 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. Contains PS00379 CDP-alcohol phosphatidyltransferases signature. BELONGS TO THE CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE CLASS-I FAMILY.;UniProt_AC=Q49839;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1840478	1840960	.	-	0	Locus=ML1526c;Name=ML1526c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML1526c, len: 160 aa. Probable conserved transmembrane protein. Highly similar to many proteins of undefined function e.g. Mycobacterium tuberculosis Rv2772c TR:O33314 (EMBL:AL008967) (157 aa), Fasta scores: E(): 0, 76.6% identity in 154 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CBV7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1486028	1488355	.	+	0	Locus=ML1246;Name=plsB;Function=;Product=PROBABLE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE PLSB2 (GPAT);Comments=ML1246, len: 775 aa. Probable plsB2, glycerol-3-phosphate acyltransferase (EC 2.3.1.15). Highly similar to many acyltransferases including: Escherichia coli glycerol-3-phosphate acyltransferase (EC 2.3.1.15) SW:PLSB_ECOLI (P00482) (806 aa), Fasta scores: E(): 1.5e-27, 24.4% identity in 693 aa overlap and Mycobacterium tuberculosis putative acyltransferase PlsB2 Rv2482c SW:PLS2_MYCTU (O53207) (789 aa), Fasta scores: E(): 0, 80.7% identity in 783 aa overlap. Contains Pfam match to entry PF01553 Acyltransferase, Acyltransferase.;UniProt_AC=Q9X7B0;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	983360	983422	.	+	0	Locus=ML0828A;Name=ML0828A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0828A, len:62. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.006 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1123020	1124825	.	-	0	Locus=ML0955c;Name=ppdK;Function=;Product=PROBABLE PYRUVATE, PHOSPHATE DIKINASE PPDK;Comments=ML0955c, len: 601 aa. Probable ppdK, pyruvate, phosphate dikinase (EC 2.7.9.1). Identical to the previously sequenced Mycobacterium leprae pyruvate, phosphate dikinase TR:O05566 (EMBL:Z94723) (601 aa), Fasta scores: E(): 0, 99.8% identity in 601 aa overlap. Also highly similar to pyruvate, phosphate dikinases from Mycobacterium tuberculosis Rv1127c TR:O06579 (EMBL:Z95585) (490 aa), Fasta scores: E(): 0, 71.8% identity in 478 aa overlap and Clostridium symbiosumSW:PODK_CLOSY (P22983) (873 aa), Fasta scores: E(): 0, 35.2% identity in 537 aa overlap. Contains Pfam match to entry PF00391 PEP-utilizers, PEP-utilizing enzymes. Contains Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain.;UniProt_AC=O05566;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1381007	1382272	.	-	0	Locus=ML1182c;Name=PPE;Function=;Product=PPE-family protein;Comments=ML1182c, len: 421 aa. Member of the PPE protein family. Identical to the previously sequenced Mycobacterium leprae putative PPE protein TR:Q9Z5K0 (EMBL:AL049191) (421 aa), Fasta scores: E(): 0, 100.0% identity in 421 aa overlap. Also highly similar to many members of the Mycobacterium tuberculosis PPE-family of proteins e.g. O05298 Rv1196 (391 aa), fasta scores: E(): 3e-23, (41.135% identity in 423 aa overlap) and Rv2892c SW:YS92_MYCTU (Q10813) (408 aa), Fasta scores: E(): 1.2e-25, 34.0% identity in 429 aa overlap. Also similar to ML1054 a possible pseudogene similar to M. tuberculosis Rv1196. Contains Pfam match to entry PF00823 PPE, PPE family.;UniProt_AC=Q9Z5K0;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	1190923	1191897	.	-	0	Locus=ML1023c;Name=ppgK;Function=;Product=probable polyphosphate glucokinase PpgK (POLYPHOSPHATE-GLUCOSE PHOSPHOTRANSFERASE);Comments=ML1023c, len: 324 aa. Probable ppgK, polyphosphate glucokinase (EC 2.7.1.63). Identical to the previously sequenced Mycobacterium leprae polyphosphate glucokinase (EC 2.7.1.63) SW:PPGK_MYCLE (Q49988) (324 aa), Fasta scores: E(): 0, 99.7% identity in 324 aa overlap catalysing the phosphorylation of glucose thereby generating D-glucose 6-phosphate. Also highly similar to Mycobacterium tuberculosis Rv2702 SW:PPGK_MYCTU (Q59568) (265 aa), Fasta scores: E(): 0, 82.8% identity in 262 aa overlap. Note the predicted translational start site for this CDS maybe incorrect due to the overlap with CDS ML1024.;UniProt_AC=Q49988;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1566115	1566960	.	+	0	Locus=ML1313;Name=ML1313;Function=;Product=POSSIBLE RNA METHYLTRANSFERASE;Comments=ML1313, len: 281 aa. Possible RNA methyltransferase (EC 2.1.1.-). Highly similar to several proteins of unknown function and Mycobacterium tuberculosis Rv2118c TR:O33253 (EMBL:Z97559) Possible RNA methyltransferase (280 aa), Fasta scores: E(): 0, 84.0% identity in 281 aa overlap.;UniProt_AC=Q9S376;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1556855	1560475	.	+	0	Locus=ML1307;Name=metH;Function=;Product=Probable 5-methyltetrahydrofolate--homocystein methyltransferase MetH (Methionine synthase, vitamin-B12 dependent isozyme) (MS);Comments=ML1307, len: 1206 aa. Probable 5-methyltetrahydrofolate--homocystein methyltransferase (EC 2.1.1.13).  Highly similar to many 5-methyltetrahydrofolate--homocysteine methyltransferases involved in methionine biosynthesis, including: Escherichia coli MetH SW:METH_ECOLI (P13009) (1226 aa), Fasta scores: E(): 0, 31.6% identity in 1233 aa overlap and Mycobacterium tuberculosis Rv2124c SW:METH_MYCTU (O33259) (1192 aa), Fasta scores: E(): 0, 88.3% identity in 1204 aa overlap.;UniProt_AC=Q49775;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1328503	1329702	.	+	0	Locus=ML1137;Name=rfe;Function=;Product=PROBABLE UNDECAPAPRENYL-PHOSPHATE ALPHA-N-ACETYLGLUCOSAMINYLTRANSFERASE RFE (UDP-GlcNAc TRANSFERASE);Comments=ML1137, len: 399 aa. Probable rfe, undecaprenyl-phosphatealpha-N-acetylglucosaminyltransferase (EC 2.4.1.-). Previously sequenced Mycobacterium leprae SW:RFE_MYCLE (P45830) (398 aa), Fasta scores: E(): 0, 99.7% identity in 398 aa overlap. Similar to many including: Mycobacterium tuberculosis putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase SW:RFE_MYCTU (Q10606) (404 aa), Fasta scores: E(): 0, 89.2% identity in 398 aa overlap and Bacillus subtilis phospho-N-acetylmuramoyl-pentapeptide-transferase SW:MRAY_BACSU (Q03521) (324 aa), Fasta scores: E(): 1.9e-07, 28.6% identity in 297 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00953 Glycos_transf_4, Glycosyl transferase.;UniProt_AC=P45830;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1325477	1325731	.	+	0	Locus=ML1133;Name=rpmE;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L31 RPME;Comments=ML1133, len: 84 aa. Probable rpmE, 50S ribosomal protein L31. Identical to the previously sequenced Mycobacterium leprae 50s ribosomal protein L31 SW:RL31_MYCLE (P45834) (84 aa), Fasta scores: E(): 0, 100.0% identity in 84 aa overlap, as well as being highly similar to many others e.g. Mycobacterium tuberculosis Rv1298 SW:RL31_MYCTU (Q10608) (80 aa), Fasta scores: E(): 5.8e-27, 89.6% identity in 77 aa overlap and Escherichia coli SW:RL31_ECOLI (P02432) (70 aa), Fasta scores: E(): 3.4e-11, 53.8% identity in 65 aa overlap. Contains Pfam match to entry PF01197 Ribosomal_L31, Ribosomal protein L31. Contains PS00190 Cytochrome c family heme-binding site signature. Contains PS01143 Ribosomal protein L31 signature.;UniProt_AC=P45834;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1251535	1252713	.	+	0	Locus=ML1089;Name=sugC;Function=;Product=PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC;Comments=ML1089, len: 392 aa. Probable sugC, sugar-transport ATP-binding protein ABC transporter. Identical to the previously sequenced Mycobacterium leprae TR:Q49978 (EMBL:U15180) (392 aa), Fasta scores: E(): 0, 100.0% identity in 392 aa overlap. Also highly similar to many ABC-transport proteins including: Mycobacterium tuberculosis Rv1238 TR:O50454 (EMBL:AL021006) (393 aa), Fasta scores: E(): 0, 79.9% identity in 389 aa overlap and Agrobacterium radiobacter SW:LACK_AGRRD (Q01937) (363 aa), Fasta scores: E(): 0, 53.1% identity in 339 aa overlap lactose transport ATP-binding protein. Also similar to ML1424 from M. leprae. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).;UniProt_AC=Q49978;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1833030	1833830	.	-	0	Locus=ML1519c;Name=thyA;Function=;Product=PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE);Comments=ML1519c, len: 266 aa. Probable thyA, thymidylate synthase (EC 2.1.1.45). Highly similar to many thymidylate synthases involved in deoxyribonucleotide biosynthesis including: Escherichia coli SW:TYSY_ECOLI (P00470) (264 aa), Fasta scores: E(): 0, 66.3% identity in 261 aa overlap and Mycobacterium tuberculosis Rv2764c SW:TYSY_MYCTU (O33306) (263 aa), Fasta scores: E(): 0, 85.5% identity in 262 aa overlap. Contains Pfam match to entry PF00303 thymidylat_synt, Thymidylate synthase. Contains PS00091 Thymidylate synthase active site.;UniProt_AC=Q9CBW0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1546965	1547717	.	+	0	Locus=ML1298;Name=ML1298;Function=;Product=conserved hypothetical protein;Comments=ML1298, len: 250 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2135c TR:O06240 (EMBL:Z95388) (236 aa), Fasta scores: E(): 0, 75.2% identity in 250 aa overlap. Also similar, in regions, to several putative phosphoglycerate mutases e.g. Escherichia coli SW:PMG2_ECOLI (P36942) (215 aa), Fasta scores: E(): 1.2e-06, 27.1% identity in 192 aa overlap. Contains Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase family.;UniProt_AC=Q9CC41;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1567376	1567960	.	-	0	Locus=ML1315c;Name=lppK;Function=;Product=Probable conserved lipoprotein LppK;Comments=ML1315c, len: 194 aa. Probable lppK, conserved lipoprotein. Highly similar to Mycobacterium tuberculosis putative lipoprotein LppK (Rv2116) SW:LPPK_MYCTU (O33251) (189 aa), Fasta scores: E(): 1.4e-29, 51.6% identity in 188 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q49803;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1575685	1576560	.	+	0	Locus=ML1322;Name=prcB;Function=;Product=proteasome (beta subunit) PrcB;Comments=ML1322, len: 291 aa. Probable prcB, proteasome beta-type subunit 2 (EC 3.4.25.1). Highly similar to many proposed 20S proteasome beta subunits including: Methanococcus jannaschii SW:PRCB_METJA (Q58634) (224 aa), Fasta scores: E(): 0.00015, 29.0% identity in 183 aa overlap, Rhodococcus sp. TR:Q53079 (EMBL:U26421) (294 aa), Fasta scores: E(): 0, 63.5% identity in 266 aa overlap and Mycobacterium tuberculosis Rv2110c TR:O33245 (EMBL:Z97559) (291 aa), Fasta scores: E(): 0, 81.0% identity in 290 aa overlap. Contains Pfam match to entry PF00227 proteasome, Proteasome A-type and B-type.;UniProt_AC=Q49780;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1612179	1613459	.	+	0	Locus=ML1352;Name=tyrS;Function=;Product=Probable Tyrosyl-tRNA synthase TyrS (TYRRS);Comments=ML1352, len: 426 aa. Probable Tyrosyl-tRNA synthase (EC 6.1.1.1). Highly similar to many tyrosyl-tRNA synthetases including: Bacillus stearothermophilus SW:SYY_BACST (P00952) (419 aa), Fasta scores: E(): 0, 50.2% identity in 416 aa overlap and Mycobacterium tuberculosis Rv1689 SW:SYY_MYCTU (O33191) (424 aa), Fasta scores: E(): 0, 83.6% identity in 426 aa overlap. Contains Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature.;UniProt_AC=Q49900;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1621827	1623008	.	+	0	Locus=ML1361;Name=ML1361;Function=;Product=conserved membrane protein;Comments=ML1361, len: 393 aa. Conserved membrane protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1697 TR:O33198 (EMBL:Z98268) (393 aa), Fasta scores: E(): 0, 90.6% identity in 393 aa overlap. Contains possible membrane spanning hydrophobic domain at the C-terminal end.;UniProt_AC=Q9CC30;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1630439	1631212	.	+	0	Locus=ML1370;Name=ML1370;Function=;Product=Hypothetical pseudouridine synthase (Uracil hydrolyase);Comments=ML1370, len: 257 aa. Hypothetical pseudouridine synthase (EC 4.2.1.70). Highly similar to several pseudouridylate synthases involved in the modification of ribosomal RNA e.g. Bacillus subtilis ribosomal large subunit pseudouridine synthase B SW:RLUB_BACSU (P35159) (229 aa), Fasta scores: E(): 3.6e-30, 42.8% identity in 229 aa overlap. Also highly similar to Mycobacterium tuberculosis Rv1711 SW:YH11_MYCTU (O33210) (254 aa), Fasta scores: E(): 0, 80.2% identity in 257 aa overlap. Contains Pfam match to entry PF01479 S4, S4 domain. Contains Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase. Contains PS01149 Rsu family of pseudouridine synthase signature. Belongs to the pseudouridine synthase rsuA family. ;UniProt_AC=O05668;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1667053	1667496	.	+	0	Locus=ML1390;Name=ML1390;Function=;Product=IRON-REGULATED CONSERVED HYPOTHETICAL PROTEIN TB15.3 HOMOLOG;Comments=ML1390, len: 147 aa. Possible iron-regulated conserved hypothetical protein TB15.3 homolog.  Highly similar to Mycobacterium tuberculosis Rv1636 TR:O06153 (EMBL:Z95554) TB15.3 iron-regulated conserved hypothetical protein (146 aa), Fasta scores: E(): 0, 89.0% identity in 146 aa overlap and Neisseria meningitidis TR:AAF41856 (EMBL:AE002499) Hypothetical protein (154 aa), Fasta scores: E(): 1.7e-07, 32.4% identity in 148 aa overlap. Contains Pfam match to entry PF00582 Usp, Universal stress protein family.;UniProt_AC=Q9CC26;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1667505	1668203	.	-	0	Locus=ML1391c;Name=ML1391c;Function=;Product=conserved hypothetical protein;Comments=ML1391c, len: 232 aa. Conserved hypothetical protein. Similar to several including: Streptomyces coelicolor putative hydrolase TR:Q9Z505 (EMBL:AL035591) (218 aa), Fasta scores: E(): 0, 50.9% identity in 224 aa overlap and in parts to Rhodopseudomonas blastica probable hydroxyacylglutathione hydrolase SW:GLO2_RHOBL (P05446) (255 aa), Fasta scores: E(): 2.4e-08, 37.9% identity in 145 aa overlap. Also similar to Mycobacterium tuberculosis hypothetical protein Rv1637c TR:O06154 (EMBL:Z95554) (264 aa), Fasta scores: E(): 0, 84.0% identity in 231 aa overlap. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily.;UniProt_AC=Q9CC25;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1671927	1675046	.	-	0	Locus=ML1393c;Name=lysX;Function=;Product=Possible lysyl-tRNA synthetase 2 LysX;Comments=ML1393c, len: 1039 aa. Possible lysX, lysyl-tRNA synthetase 2 (EC 6.1.1.6). Similar to Mycobacterium tuberculosis Rv1640c TR:P94974 (EMBL:Z85982) (1172 aa), Fasta scores: E(): 0, 82.0% identity in 1041 aa overlap and Q825Z7 Putative lysyl-tRNA synthetase from Streptomyces avermitilis (1093 aa), fasta scores: E(): 2.3e-176, (55.673% identity in 1040 aa overlap). The C-terminal region of the predicted product of this CDS is highly similar to many other lysyl-tRNA synthetases including Haemophilus influenzae SW:SYK_HAEIN (P43825) (502 aa), Fasta scores: E(): 0, 40.1% identity in 504 aa overlap. The N-terminus is similar to several proposed membrane proteins e.g. Streptomyces coelicolor TR:O69916 (EMBL:AL023861) (589 aa), Fasta scores: E(): 0, 47.8% identity in 510 aa overlap. Also similar to ML0233 from M. leprae. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N). Contains PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.;UniProt_AC=Q9CC23;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1676419	1676613	.	+	0	Locus=ML1395;Name=rpmI;Function=;Product=Probable 50S ribosomal protein L35 RpmI;Comments=ML1395, len: 64 aa. Probable rpmI, 50S ribosomal protein L35. Highly similar to many 50s ribosomal L35 proteins, including: Escherichia coli SW:RL35_ECOLI (P07085) (64 aa), Fasta scores: E(): 2.3e-05, 43.4% identity in 53 aa overlap and Mycobacterium tuberculosis Rv1642 SW:RL35_MYCTU (P94976) (64 aa), Fasta scores: E(): 1.6e-24, 90.6% identity in 64 aa overlap. Contains Pfam match to entry PF01632 Ribosomal_L35p, Ribosomal protein L35. Belongs to the L35P family of ribosomal proteins. ;UniProt_AC=Q9CC21;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1668341	1671250	.	+	0	Locus=ML1392;Name=uvrA;Function=INVOLVED IN NUCLEOTIDE EXCISION REPAIR. THE ABC EXCISION NUCLEASE IS A DNA REPAIR ENZYME THAT CATALYZES THE EXCISION REACTION OF UV-DAMAGED NUCLEOTIDE SEGMENTS PRODUCING OLIGOMERS HAVING THE MODIFIED BASE(S). UVRA IS AN ATPASE AND A DNA-BINDING PROTEIN THAT PREFERENTIALLY BINDS SINGLE-STRANDED OR UV-IRRADIATED DOUBLE-STRANDED DNA.;Product=PROBABLE EXCINUCLEASE ABC (SUBUNIT A - DNA-BINDING ATPase) UVRA;Comments=ML1392, len: 969 aa. Probable excinuclease ABC subunit A> Highly similar to many excinucleases ABC (subunit A), involved in DNA repair following UV damage, including: Micrococcus luteus SW:UVRA_MICLU (P13567) (992 aa), Fasta scores: E(): 0, 69.3% identity in 966 aa overlap and Mycobacterium tuberculosis Rv1638 SW:UVRA_MYCTU (P94972) (972 aa), Fasta scores: E(): 0, 90.9% identity in 975 aa overlap. Contains 2 Pfam matches to entry PF00005 ABC_tran, ABC transporter. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CC24;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1687676	1688719	.	+	0	Locus=ML1406;Name=argC;Function=;Product=PROBABLE N-ACETL-GAMMA-GLUTAMYL-PHOSHATE REDUCTASE ARGC;Comments=ML1406, len: 347 aa. Probable argC, N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38). Highly similar to many N-acetyl-gamma-glutamyl-phosphate reductases involved in arginine biosynthesis, including: Streptomyces coelicolor SW:ARGC_STRCO (AL031541) (342 aa), Fasta scores: E(): 0, 62.1% identity in 346 aa overlap and Mycobacterium tuberculosis Rv1652 SW:ARGC_MYCTU (P94987) (352 aa), Fasta scores: E(): 0, 81.1% identity in 344 aa overlap. Contains Pfam match to entry PF01118 Semialdhyde_dh, Semialdehyde dehydrogenase. Contains PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site.;UniProt_AC=Q9CC15;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1688716	1689939	.	+	0	Locus=ML1407;Name=argJ;Function=;Product=Probable Glutamate n-acetyltransferase ArgJ;Comments=ML1407, len: 407 aa. Probable argJ, Glutamate n-acetyltransferase (EC 2.3.1.35). Highly similar to many glutamate N-acetyltransferases including: Corynebacterium glutamicum SW:ARGJ_CORGL (Q59280) (388 aa), Fasta scores: E(): 0, 58.2% identity in 392 aa overlap and Mycobacterium tuberculosis Rv1653 TR:P94988 (EMBL:Z85982) (404 aa), Fasta scores: E(): 0, 82.4% identity in 404 aa overlap. Contains Pfam match to entry PF01960 ArgJ, ArgJ family.;UniProt_AC=Q9CC14;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1681041	1682093	.	+	0	Locus=ML1401;Name=pheS;Function=;Product=Probable phenylalanyl-tRNA synthetase, alpha chain PheS;Comments=ML1401, len: 350 aa. Probable pheS, phenylalanyl-tRNA synthetase, alpha chain (EC 6.1.1.20). Highly similar to many phenylalanyl-tRNA synthetase alpha chains including: Escherichia coli SW:SYFA_ECOLI (P08312) (327 aa), Fasta scores: E(): 0, 45.9% identity in 331 aa overlap and Mycobacterium tuberculosis Rv1649 TR:P94984 (EMBL:Z85982) (341 aa), Fasta scores: E(): 0, 85.0% identity in 341 aa overlap. Contains Pfam match to entry PF01409 tRNA-synt_2d, tRNA synthetases class II (F). Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.;UniProt_AC=Q9CC17;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1787390	1787878	.	-	0	Locus=ML1484c;Name=ML1484c;Function=;Product=PROBABLE ISOMERASE;Comments=ML1484c, len: 162 aa. Probable isomerase (EC 5.-.-.-). Similar to many isomerases including: Escherichia coli ribose 5-phosphate isomerase B (EC 5.3.1.6) SW:RPIB_ECOLI (P37351) (149 aa), Fasta scores: E(): 2.8e-12, 32.9% identity in 146 aa overlap and Mycobacterium tuberculosis isomerase Rv2465c TR:O53192 (EMBL:AL021246) (162 aa), Fasta scores: E(): 0, 89.5% identity in 162 aa overlap.;UniProt_AC=Q9CBY1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1700700	1701248	.	-	0	Locus=ML1418c;Name=ML1418c;Function=;Product=conserved hypothetical protein;Comments=ML1418c, len: 182 aa. Conserved hypothetical protein. Highly similar to several proteins of undefined function including: Mycobacterium tuberculosis Rv1732c TR:P71990 (EMBL:Z81360) (182 aa), Fasta scores: E(): 0, 86.3% identity in 182 aa overlap and Synechocystis sp. TR:P73178 (EMBL:D90904) (194 aa), Fasta scores: E(): 0, 52.5% identity in 179 aa overlap.;UniProt_AC=Q9CC07;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1050580	1050769	.	+	0	Locus=ML0884A;Name=ML0884A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0884A, len:189. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 9.00E-09 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1704358	1706049	.	-	0	Locus=ML1419c;Name=ML1419c;Function=;Product=Possible regulatory protein;Comments=ML1419c, len: 563 aa. Possible regulatory protein. The N-terminus is similar to several sensory box proteins e.g. Q884C4 Sensory box/GGDEF domain/EAL domain protein from Pseudomonas syringae (730 aa), fasta scores: E(): 3.8e-22, (34.557% identity in 327 aa overlap). The C-terminus is similar to many hyptothetical proteins. Contains 3 Pfam matches to entry PF00989 PAS, PAS domain. Contains Pfam match to entry PF00990 GGDEF domain.;UniProt_AC=O32949;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1710511	1711500	.	-	0	Locus=ML1423c;Name=ML1423c;Function=;Product=conserved hypothetical protein;Comments=ML1423c, len: 329 aa. Conserved hypothetical protein. Highly similar to several proteins of undefined function including: Bacillus subtilis SW:YQHO_BACSU (P54513) (291 aa), Fasta scores: E(): 2.8e-24, 37.3% identity in 308 aa overlap and Mycobacterium tuberculosis Rv2037c TR:O53481 (EMBL:AL021899) (324 aa), Fasta scores: E(): 0, 80.5% identity in 323 aa overlap.;UniProt_AC=O32943;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1819561	1820052	.	-	0	Locus=ML1508c;Name=ML1508c;Function=;Product=conserved hypothetical protein;Comments=ML1508c, len: 163 aa. Conserved hypothetical protein. Highly similar to several proteins of undefined function including M. tuberculosis Rv1155 TR:O06553 (EMBL:Z95584) (147 aa), Fasta scores: E(): 0, 87.8% identity in 147 aa overlap and Streptomyces coelicolor TR:Q9XAG1 (EMBL:AL079356) (144 aa), Fasta scores: E(): 5.6e-25, 54.3% identity in 140 aa overlap.;UniProt_AC=Q9CBW7;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1781330	1782211	.	+	0	Locus=ML1478;Name=mmuM;Function=CATALYZES METHYL TRANSFER FROM S-METHYLMETHIONINE OR S-ADENOSYLMETHIONINE (LESS EFFICIENT) TO HOMOCYSTEINE, SELENOHOMOCYSTEINE AND LESS EFFICIENTLY SELENOCYSTEINE [CATALYTIC ACTIVITY: S-ADENOSYL-L-METHIONINE + L-HOMOCYSTEINE = S-ADENOSYL-L-HOMOCYSTEINE + L-METHIONINE].;Product=PROBABLE HOMOCYSTEINE S-METHYLTRANSFERASE MMUM (S-METHYLMETHIONINE:HOMOCYSTEINE METHYLTRANSFERASE) (CYSTEINE METHYLTRANSFERASE);Comments=ML1478, len: 293 aa. Probable mmuM, homocysteine S-methyltransferase (EC 2.1.1.10).  Highly similar to many e.g. Escherichia coli homocysteine S-methyltransferase involved in methionine biosynthesis SW:MMUM_ECOLI (Q47690) (310 aa), Fasta scores: E(): 0, 49.8% identity in 293 aa overlap and Mycobacterium tuberculosis putative transferase Rv2458 TR:O53185 (302 aa), fasta score: E(): 7e-92, (78.840% identity in 293 aa overlap).;UniProt_AC=Q9CBY5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1782208	1782852	.	-	0	Locus=ML1479c;Name=clpP2;Function=;Product=PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2);Comments=ML1479c, len: 214 aa. Probable clpP2, ATP-dependent Clp protease proteolytic subunit 2. Highly similar to many ATP-dependent Clp protease proteolytic subunits (EC 3.4.21.92) including: Yersinia enterocolitica SW:CLPP_YEREN (Q60107) (207 aa), Fasta scores: E(): 0, 47.1% identity in 204 aa overlap and Mycobacterium tuberculosis Rv2460c SW:CLP2_MYCTU (O53187) (214 aa), Fasta scores: E(): 0, 98.1% identity in 210 aa overlap. Highly similar to the adjoining CDS ML1480 in M. leprae. Contains Pfam match to entry PF00574 CLP_protease, Clp protease. Contains PS00381 Endopeptidase Clp serine active site.;UniProt_AC=Q9CBY4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1102044	1102358	.	-	0	Locus=ML0932A;Name=ML0932A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0932A, len:314. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-07 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1782849	1783523	.	-	0	Locus=ML1480c;Name=clpP1;Function=;Product=PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP);Comments=ML1480c, len: 224 aa. Probable clpP1, ATP-dependent clp protease proteolytic subunit 1 (EC 3.4.21.92). Highly similar to many ATP-dependent Clp protease proteolytic subunits including: Bacillus subtilis SW:CLPP_BACSU (P80244) (197 aa), Fasta scores: E(): 0, 54.5% identity in 187 aa overlap and Mycobacterium tuberculosis Rv2461c SW:CLP1_MYCTU (O53188) (200 aa), Fasta scores: E(): 0, 94.5% identity in 200 aa overlap. Highly similar to the adjoining CDS ML1479. Contains Pfam match to entry PF00574 CLP_protease, Clp protease. Note that previously known as clpP.;UniProt_AC=Q9CBY3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1815366	1816658	.	-	0	Locus=ML1504c;Name=ML1504c;Function=;Product=CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML1504c, len: 430 aa. Conserved transmembrane protein. Highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis possible membrane protein Rv1159 TR:O06557 (EMBL:Z95584) (431 aa), Fasta scores: E(): 0, 75.7% identity in 420 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CBX0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1805545	1807431	.	-	0	Locus=ML1498c;Name=typA;Function=;Product=POSSIBLE GTP-BINDING TRANSLATION ELONGATION FACTOR TYPA (TYROSINE PHOSPHORYLATED PROTEIN A) (GTP-BINDING PROTEIN);Comments=ML1498c, len: 628 aa. Possible typA, GTP-binding, protein elongation factor. Highly similar to several GTP-binding proteins including: Escherichia coli SW:TYPA_ECOLI (P32132) (591 aa), Fasta scores: E(): 0, 46.1% identity in 610 aa overlap which belongs to the GTP-binding elongation factor family and Mycobacterium tuberculosis hypothetical protein Rv1165 TR:O06563 (EMBL:Z95584) (628 aa), Fasta scores: E(): 0, 85.2% identity in 628 aa overlap. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family. Contains PS00301 GTP-binding elongation factors signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CBX2;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1816762	1817310	.	+	0	Locus=ML1505;Name=ML1505;Function=;Product=CONSERVED HYPOTHETICAL ALA-, PRO-RICH PROTEIN;Comments=ML1505, len: 182 aa. Conserved hypothetical Proline rich protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1158c TR:O06556 (EMBL:Z95584) (227 aa), Fasta scores: E(): 1.1e-16, 51.7% identity in 236 aa overlap. Note the predicted product of this CDS is rich in the amino acids Pro and Ala and displays multiple ProAla repeats.;UniProt_AC=Q9CBW9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1817338	1818384	.	+	0	Locus=ML1506;Name=ML1506;Function=;Product=CONSERVED HYPOTHETICAL ALA-, PRO-RICH PROTEIN;Comments=ML1506, len: 348 aa. Conserved hypothetical ala and proline rich protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1157c TR:O06555 (EMBL:Z95584) (371 aa), Fasta scores: E(): 0, 68.0% identity in 369 aa overlap. Note the predicted product of this CDS is rich in the amino acids Pro.;UniProt_AC=Q9CBW8;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2074931	2075668	.	-	0	Locus=ML1719c;Name=ML1719c;Function=;Product=POSSIBLE TRANSFERASE;Comments=ML1719c, len: 245 aa. Possible transferase. Highly similar to Mycobacterium tuberculosis Rv3034c TR:O53281 (EMBL:AL021287) (300 aa), Fasta scores: E(): 0, 90.6% identity in 244 aa overlap. The C-terminus of this protein is weakly similar to several including: Escherichia coli putative lipopolysaccharide biosynthesis O-acetyl transferase SW:WBBJ_ECOLI (P37750) (196 aa), Fasta scores: E(): 4.3e-09, 35.8% identity in 134 aa overlap. ;UniProt_AC=Q9CBR1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1821253	1821960	.	+	0	Locus=ML1511;Name=npdA;Function=;Product=Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog);Comments=ML1511, len: 237 aa. Probable npdA, NAD-dependent deacetylase (EC 3.5.1.-). Highly similar to several e.g. Mycobacterium tuberculosis Rv1151c TR:O06549 (EMBL:Z95584) (237 aa), Fasta scores: E(): 0, 85.2% identity in 237 aa overlap and  Q8NSM4|NPD_CORGL NAD-dependent deacetylase from Corynebacterium glutamicum (Brevibacterium flavum) (258 aa), fasta scores: E(): 2e-48, (46.610% identity in 236 aa overlap). Contains Pfam match to entry PF02146 SIR2, Sir2 family. Belongs to the sirtuin family.;UniProt_AC=Q9CBW6;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1825649	1826413	.	-	0	Locus=ML1514c;Name=thyX;Function=;Product=PROBABLE THYMIDYLATE SYNTHASE THYX (TS) (TSase);Comments=ML1514c, len: 254 aa. Probable thyX, Thymidylate synthase  (EC 2.1.1.148). Highly similar to several e.g Mycobacterium tuberculosis thyX, Thymidylate synthase Rv2754c or MTV002.19C TR:O33296 (EMBL:AL008967) (250 aa) fasta scores: E(): 0, 81.5% identity in 254 aa and to Brevibacterium lactofermentum thyX, Thymidylate synthase SW:YDAP_BRELA (P40111) (250 aa) fasta scores: E(): 0, 59.4% identity in 249 aa. Also similar to mycobacteriophage proteins; Mycobacteriophage D29 protein 48 SW:VG48_BPMD2 (O64238) (235 aa) fasta scores: E(): 4.9e-30, 43.8% id in 249 aa ;UniProt_AC=Q9CBW3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1832480	1832977	.	-	0	Locus=ML1518c;Name=dfrA;Function=;Product=DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE);Comments=ML1518c, len: 165 aa. Probable dfrA, dihydrofolate reductase (EC 1.5.1.3). Highly similar to many dihydrofolate reductases including: Escherichia coli SW:DYR_ECOLI (P00379) (159 aa), Fasta scores: E(): 2e-15, 38.4% identity in 146 aa overlap and several reductases from Mycobacteria including M. tuberculosis Rv2763c TR:O30463 (EMBL:AF006616) (181 aa), Fasta scores: E(): 0, 68.9% identity in 161 aa overlap and M. avium TR:O30463. Contains Pfam match to entry PF00186 DiHfolate_red, Dihydrofolate reductase. Contains PS00075 Dihydrofolate reductase signature. Note previously known as folA.;UniProt_AC=Q9CBW1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1689936	1690841	.	+	0	Locus=ML1408;Name=argB;Function=;Product=Probable Acetylglutamate kinase ArgB (NAG kinase) (N-acetyl-L-glutamate 5-phosphotransferase );Comments=ML1408, len: 301 aa. Probable argB, Acetylglutamate kinase (EC 2.7.2.8). Highly similar to many acetylglutamate kinases involved in arginine biosynthesis, including: Corynebacterium glutamicum SW:ARGB_CORGL (Q59281) (294 aa), Fasta scores: E(): 0, 64.1% identity in 270 aa overlap and Mycobacterium tuberculosis Rv1654 SW:ARGB_MYCTU (P94989) (294 aa), Fasta scores: E(): 0, 87.5% identity in 288 aa overlap. Contains Pfam match to entry PF01960 ArgJ, ArgJ family. Contains Pfam match to entry PF00696 aakinase, Amino acid kinase family. Belongs to the acetylglutamate kinase family. ;UniProt_AC=Q9CC13;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1699652	1700458	.	+	0	Locus=ML1417;Name=cdh;Function=;Product=possible CDP-diacylglycerol pyrophosphatase Cdh (CDP-diacylglycerol diphosphatase) (CDP-diacylglycerol phosphatidylhydrolase) ;Comments=ML1417, len: 268 aa. Possible CDP-diacylglycerol pyrophosphatase. Similar to several CDP-diacylglycerol pyrophosphatases (EC 3.6.1.26) involved in phospholipid biosynthesis, including: CDH_SALTY|P26219 from Salmonella typhimurium (251 aa), Fasta scores: E(): 1.6e-25, (39.1% identity in 220 aa overlap) and Rv2289|CDH_MYCTU|Q50676 from Mycobacterium tuberculosis (260 aa), Fasta scores: E(): 0, (66.4% identity in 256 aa overlap).;UniProt_AC=Q9CC08;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1824631	1825533	.	-	0	Locus=ML1513c;Name=dapA;Function=;Product=PROBABLE DIHYDRODIPICOLINATE SYNTHASE DAPA (DHDPS) (DIHYDRODIPICOLINATE SYNTHETASE);Comments=ML1513c, len: 300 aa. Probable dapA, dihydrodipicolinate synthase (EC 4.2.1.52). Highly similar to many dihydrodipicolinate synthases including: Brevibacterium lactofermentum SW:DAPA_BRELA (P40109) (301 aa), Fasta scores: E(): 0, 58.0% identity in 288 aa overlap and Mycobacterium tuberculosis Rv2753c TR:O33295 (EMBL:AL008967) (300 aa), Fasta scores: E(): 0, 86.7% identity in 300 aa overlap. Contains Pfam match to entry PF00701 DHDPS, Dihydrodipicolinate synthetase family. Contains PS00665 Dihydrodipicolinate synthetase signature 1. Contains PS00666 Dihydrodipicolinate synthetase signature 2.;UniProt_AC=Q9CBW4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1675811	1676368	.	+	0	Locus=ML1394;Name=infC;Function=;Product=PROBABLE INITIATION FACTOR IF-3 INFC;Comments=ML1394, len: 185 aa. Probable infC, initiation factor IF-3. Highly similar to many translation initiation factors (3) including: Neisseria meningitidis TR:AAF41134 (EMBL:AE002426) (155 aa), Fasta scores: E(): 3.8e-28, 48.7% identity in 152 aa overlap, Bacillus subtilis SW:IF3_BACSU (P55872) (171 aa), Fasta scores: E(): 1.4e-26, 48.7% identity in 150 aa overlap and Mycobacterium tuberculosis Rv1641 SW:IF3_MYCTU (P94975) (201 aa), Fasta scores: E(): 0, 89.2% identity in 185 aa overlap. Contains Pfam match to entry PF00707 IF3, Translation initiation factor IF-3. Contains PS00938 Initiation factor 3 signature.;UniProt_AC=Q9CC22;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1537588	1538118	.	+	0	Locus=ML1289;Name=ML1289;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN TB18.6 HOMOLOG;Comments=ML1289, len: 176 aa. Conserved hypothetical protein. Similar to many proteins of undefined function including: Mycobacterium tuberculosis Rv2140c SW:YL40_MYCTU (O06235) (176 aa), Fasta scores: E(): 0, 86.3% identity in 175 aa overlap and Escherichia coli SW:YBCL_ECOLI (P77368) (183 aa), Fasta scores: E(): 1.1e-21, 45.3% identity in 161 aa overlap. Note this CDS contains a strong Pfam hit to the Eukaryotic phosphatidylethanolamine-binding protein motif. In Eukaryotes this motif is associated with the binding of hydrophobic ligands and nucleotides. Contains Pfam match to entry PF01161 PBP, Phosphatidylethanolamine-binding protein.;UniProt_AC=Q9CC45;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1872644	1873609	.	-	0	Locus=ML1548c;Name=ML1548c;Function=;Product=conserved hypothetical protein;Comments=ML1548c, len: 321 aa. Conserved hypothetical protein. Highly similar to several proteins of unknown function including:  Streptomyces coelicolor TR:O88028 (EMBL:AL031107) (295 aa), Fasta scores: E(): 0, 54.4% identity in 285 aa overlap and Mycobacterium tuberculosis TR:O33337 (EMBL:AL00896) (324 aa), Fasta scores: E(): 0, 87.4% identity in 318 aa overlap.;UniProt_AC=Q9Z5I6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1619878	1621641	.	+	0	Locus=ML1360;Name=recN;Function=;Product=PROBABLE DNA REPAIR PROTEIN RECN (RECOMBINATION PROTEIN N);Comments=ML1360, len: 587 aa. Probable recN, DNA repair protein. Highly similar to many recombinational repair protein (RecN) orthologues including: Bacillus subtilis SW:RECN_BACSU (P17894) (576 aa), Fasta scores: E(): 7.4e-26, 30.3% identity in 597 aa overlap and Mycobacterium tuberculosis Rv1696 TR:O33197 (EMBL:Z98268) (587 aa), Fasta scores: E(): 0, 76.2% identity in 589 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q49896;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1713481	1714440	.	-	0	Locus=ML1426c;Name=ML1426c;Function=;Product=Probable sugar-transport integral membrane protein ABC transporter;Comments=ML1426c, len: 319 aa. Probable sugar-transport integral membrane protein ABC transporter. Highly similar to many putative ABC_transport proteins e.g. Mycobacterium tuberculosis sugar transport protein Rv2040c TR:O53484 (EMBL:AL021899) (300 aa), Fasta scores: E(): 0, 81.6% identity in 293 aa overlap. Also similar to ML1768 from M. leprae. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign.;UniProt_AC=O32940;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1801892	1802818	.	-	0	Locus=ML1495c;Name=mshB;Function=Involved in  mycothiol biosynthesis. 1-D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins)is converted to 1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside (GlcN-Ins) by this enzyme. Seems to possess weak mycothiol conjugate amidase activity but shows substantial deacetylation activity with 1-D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins), a hypothetical mycothiol biosynthetic precursor. GlcNAc-Ins is an intermediate in MSH biosynthesis.;Product=N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase);Comments=ML1495c, len: 308 aa. Probable mshB, N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase.  Highly similar to Mycobacterium tuberculosis Rv1170 TR:O50426 mshB (EMBL:AL010186) (303 aa), Fasta scores: E(): 0, 76.9% identity in 307 aa overlap and several proteins of unknown function including: Streptomyces lincolnensis LmbE TR:Q54358 (EMBL:X79146) (270 aa), Fasta scores: E(): 7.4e-13, 32.4% identity in 275 aa overlap and . Also similar to ML2391 from M. leprae.;UniProt_AC=Q9CBX4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1846971	1848086	.	+	0	Locus=ML1532;Name=ald;Function=;Product=SECRETED L-ALANINE DEHYDROGENASE ALD (40 KDA ANTIGEN) (TB43);Comments=ML1532, len: 371 aa. Probable ald, secreted L-alanine dehydrogenase (EC 1.4.1.1). Highly similar to many alanine dehydrogenases including: Bacillus sphaericus SW:DHA_BACSH (P175566) (372 aa), Fasta scores: E(): 0, 53.4% identity in 365 aa overlap and Mycobacterium tuberculosis Rv2780 SW:DHA_MYCTU (P30234) (371 aa), Fasta scores: E(): 0, 85.4% identity in 371 aa overlap. Contains Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase. Contains PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. Contains PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1.;UniProt_AC=Q9CBV6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2231745	2231930	.	-	0	Locus=ML1846c;Name=rpsN;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S14 RPSN;Comments=ML1846c, len: 61 aa. Probable rpsN, 30S ribosomal protein S14. Similar to M. tuberculosis 30S ribosomal protein S14-1 Rv0717 SW:R14A_MYCTU (P95065) (61 aa), Fasta scores: E(): 1.8e-25, 91.8% identity in 61 aa overlap. Contains Pfam match to entry PF00253 Ribosomal_S14, Ribosomal protein S14p/S29e. Contains PS00527 Ribosomal protein S14 signature.;UniProt_AC=O32996;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2761260	2761610	.	-	0	Locus=ML2330c;Name=ML2330c;Function=;Product=conserved hypothetical protein;Comments=ML2330c, len: 116 aa. Conserved hypothetical protein. Highly similar to several proteins of undefined function including: Mycobacterium tuberculosis hypothetical protein Rv3716c TR:O69683 (EMBL:AL022121) (133 aa) fasta scores: E(): 4e-27, 83.7% identity in 104 aa, and Escherichia coli hypothetical 12.0 kDa protein SW:YBAB_ECOLI (P17577; P09994) (109 aa) fasta scores: E(): 9.7e-08, 35.0% identity in 100 aa. Note the N-terminus is rich in the amino acid Gln.;UniProt_AC=O69519;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1583614	1584474	.	+	0	Locus=ML1332;Name=tatC;Function=INVOLVED IN PROTEINS EXPORT: REQUIRED FOR CORRECT LOCALIZATION OF PRECURSOR PROTEINS BEARING SIGNAL PEPTIDES WITH THE TWIN ARGININE CONSERVED MOTIF S/T-R-R-X-F-L-K. THIS SEC-INDEPENDENT PATHWAY IS TERMED TAT FOR TWIN-ARGININE TRANSLOCATION SYSTEM. THIS SYSTEM MAINLY TRANSPORTS PROTEINS WITH BOUND COFACTORS THAT REQUIRE FOLDING PRIOR TO EXPORT.;Product=Probable Sec-independent protein translocase transmembrane protein TatC;Comments=ML1332, len: 286 aa. Probable tatC, Sec-independent protein translocase transmembrane protein. Similar to many membrane proteins including: Escherichia coli Sec-independent protein translocase protein TatC SW:TATC_ECOLI (AJ005830) (258 aa), Fasta scores: E(): 1.6e-17, 33.0% identity in 267 aa overlap and Mycobacterium tuberculosis Rv2093c SW:YK93_MYCTU (Q10702) (308 aa), Fasta scores: E(): 0, 86.0% identity in 286 aa overlap. Contains multiple possible membrane spanning hydrophobic domains and a possible N-terminal signal sequence. Contains Pfam match to entry PF00902 UPF0032, MttB family. Contains PS01218 Uncharacterized protein family UPF0032 signature.;UniProt_AC=P54078;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1879675	1880169	.	-	0	Locus=ML1555c;Name=rbfA;Function=;Product=PROBABLE RIBOSOME-BINDING FACTOR A RBFA (P15B PROTEIN);Comments=ML1555c, len: 164 aa. Probable rbfA, ribosome-binding factor A. Highly similar to several ribosome-binding factors essential for efficient processing of 16s rRNA including: Escherichia coli SW:RBFA_ECOLI (P09170) (132 aa), Fasta scores: E(): 8.5e-05, 33.1% identity in 118 aa overlap and Mycobacterium tuberculosis  Rv2838c SW:RBFA_MYCTU (P71614) (183 aa), Fasta scores: E(): 0, 75.6% identity in 160 aa overlap. Contains Pfam match to entry PF02033 RBFA, Ribosome-binding factor A. Contains PS01319 Ribosome-binding factor A signature.;UniProt_AC=Q9Z5I8;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1883542	1884585	.	-	0	Locus=ML1558c;Name=nusA;Function=;Product=PROBABLE N UTILIZATION SUBSTANCE PROTEIN A NUSA;Comments=ML1558c, len: 347 aa. Probable nusA, N-utilization substance protein A. Highly similar to many transcriptional terminators/s including: Escherichia coli N utilization substance protein A SW:NUSA_ECOLI (X00513) (495 aa), Fasta scores: E(): 2e-30, 33.1% identity in 363 aa overlap and O05818|NUSA_MYCTU Transcription elongation protein from Mycobacterium tuberculosis (347 aa), fasta scores: E(): 4.5e-127, (91.931% identity in 347 aa overlap). Contains Pfam match to entry PF00013 KH-domain, KH domain.;UniProt_AC=Q9Z5J1;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1898989	1899738	.	-	0	Locus=ML1573c;Name=ML1573c;Function=;Product=possible amidotransferase;Comments=ML1573c, len: 249 aa. Possible amidotransferase (EC 6.3.5.-). Similar to several e.g. Mycobacterium tuberculosis Rv2859c TR:O33341. Also similar in regions to Dictyostelium discoideum GMP synthase (EC 6.3.5.2) (glutamine amidotransferase) SW:GUAA_DICDI (P32073) (718 aa), Fasta scores: E(): 0.0045, 26.7% identity in 176 aa overlap. Contains Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I.;UniProt_AC=Q9CBU9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1908221	1909441	.	-	0	Locus=ML1583c;Name=dxr;Function=;Product=PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERASE);Comments=ML1583c, len: 406 aa. Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.-). Highly similar to many 1-deoxy-D-xylulose 5-phosphate reductoisomerases involved in terpenoid biosynthesis e.g. Escherichia coli SW:DXR_ECOLI (P45568) (195 aa), BlastP Expect 9.4 and Mycobacterium tuberculosis Rv2870c SW:DXR_MYCTU (Q10798) (413 aa), Fasta scores: E(): 0, 84.3% identity in 395 aa overlap.;UniProt_AC=Q9CBU3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1103543	1103837	.	+	0	Locus=ML0933A;Name=ML0933A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0933A, len:294. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-11 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1900892	1901749	.	-	0	Locus=ML1576c;Name=mapB;Function=;Product=PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M);Comments=ML1576c, len: 285 aa. Probable mapB, methionine aminopeptidase (EC 3.4.11.18). Highly similar to many methionine aminopeptidases responsible for removing the amino-terminal methionine from many nascent proteins e.g. Escherichia coli SW:AMPM_ECOLI (P07906) (264 aa), Fasta scores: E(): 0, 51.4% identity in 247 aa overlap and Mycobacterium tuberculosis Rv2861c SW:AMPM_MYCTU (O33343) (285 aa), Fasta scores: E(): 0, 89.8% identity in 283 aa overlap. Contains Pfam match to entry PF00557 Peptidase_M24, metallopeptidase family M24. Contains PS00680 Methionine aminopeptidase subfamily 1 signature.;UniProt_AC=Q9CBU7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1854791	1856494	.	-	0	Locus=ML1538c;Name=mycP5;Function=;Product=PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5);Comments=ML1538c, len: 567 aa. Probable mycP5, proline rich membrane-anchored mycosin. Highly similar to several from Mycobacterium tuberculosis including: O53945|Rv1796 mycP5, proline rich membrane-anchored mycosin (585 aa), fasta scores: E(): 2e-134, (73.077% identity in 572 aa overlap); and Rv0291 TR:O53695 (EMBL:AL021930) mycP3, membrane-anchored serine protease (461 aa), Fasta scores: E(): 0, 37.6% identity in 572 aa overlap.  Also similar to ML2528 and ML0041 from M. leprae. Contains possible membrane spanning hydrophobic domain. Contains 2 Pfam matches to entry PF00082 Peptidase_S8, Subtilase family. Contains PS00136 Serine proteases. Contains PS00137 Serine proteases.;UniProt_AC=Q9CBV3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3038236	3039153	.	+	0	Locus=ML2550;Name=ML2550;Function=;Product=conserved hypothetical protein;Comments=ML2550, len: 305 aa. Conserved hypothetical protein. Similar to many proteins of undefined function including: Mycobacterium tuberculosis hypothetical 32.2 kDa protein Rv0263c TR:P95220 (EMBL:Z86089) fasta scores: E(): 0, 78.3% identity in 286 aa, and to Escherichia coli hypothetical 34.4 kDa protein in SW:YBGK_ECOLI (P75745) fasta scores: E(): 2.6e-26, 35.5% identity in 304 aa.;UniProt_AC=Q9CD25;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2048067	2049185	.	+	0	Locus=ML1699;Name=lppZ;Function=;Product=PROBABLE CONSERVED LIPOPROTEIN LPPZ;Comments=ML1699, len: 372 aa. Probable lppZ, conserved lipoprotein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv3006 TR:O53253 (EMBL:AL021287) (373 aa), Fasta scores: E(): 0, 87.1% identity in 373 aa overlap. Contains possible membrane spanning hydrophobic domains. ontains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=O33109;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2834624	2834965	.	-	0	Locus=ML2366c;Name=ML2366c;Function=;Product=POSSIBLE CONSERVED MEMBRANE PROTEIN;Comments=ML2366c, len: 113 aa. Possible conserved membrane protein. Similar to Mycobacterium tuberculosis membrane protein Rv3760 or MTV025.108 TR:O69726 (EMBL:AL022121) (100 aa) fasta scores: E(): 1.9e-19, 67.7% identity in 99 aa.  Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q50094;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2230328	2230693	.	-	0	Locus=ML1843c;Name=rplR;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L18 RPLR;Comments=ML1843c, len: 121 aa. Probable rplR, 50S ribosomal protein L18. Similar to M. tuberculosis 50S ribosomal protein L18 Rv0720 SW:RL18_MYCTU (P95068) (122 aa), Fasta scores: E(): 0, 87.5% identity in 120 aa overlap. Contains Pfam match to entry PF00861 Ribosomal_L18p, Ribosomal L18p/L5e family.;UniProt_AC=O32999;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2722017	2722991	.	+	0	Locus=ML2297;Name=ephE;Function=;Product=POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE);Comments=ML2297, len: 324 aa. Possible ephE, epoxide hydrolase (EC 3.3.2.3). Similar to Mycobacterium tuberculosis putative epoxide hydrolase Rv3670|ephE or MTV025.018 TR:O69638 (EMBL:AL022121) (327 aa) fasta scores: E(): 0, 80.6% identity in 324 aa. Similarto  many putative hydrolases and shows weak similarity to Homo sapiens soluble epoxide hydrolase ephX2 SW:HYES_HUMAN (P34913) (554 aa) fasta scores: E(): 3.1e-12, 28.1% id in 285 aa. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.;UniProt_AC=Q9CB96;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2846373	2846837	.	+	0	Locus=ML2377;Name=mmpS4;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN MMPS4;Comments=ML2377, len: 154 aa. Probable mmpS4, conserved membrane protein. Similar to Mycobacterium tuberculosis putative membrane protein Rv0451c SW:MMS4_MYCTU (O53736) (140 aa) fasta scores: E(): 0, 75.0% identity in 140 aa, and to Mycobacterium avium TmtpA TR:Q9XCF4 (EMBL:AF143772) (221 aa) fasta scores: E(): 0, 58.9% identity in 146 aa. Contains a possible N-terminal signal sequence and other possible membrane spanning hydrophobic domains.;UniProt_AC=P54880;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2604280	2605056	.	-	0	Locus=ML2189c;Name=phoT;Function=;Product=PROBABLE PHOSPHATE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER PHOT;Comments=ML2189c, len: 258 aa. Probable phoT, phosphate-transport ATP-binding protein ABC transporter. Similar to Mycobacterium tuberculosis phosphate transport system ATP-binding protein TR:O53832 (EMBL:AL022004) fasta scores: E(): 0, 91.5% in 258 aa, and to Escherichia coli phosphate transport ATP-binding protein pstb SW:PSTB_ECOLI (P07655) fasta scores: E(): 0, 52.9% in 255 aa. Also similar to ML1892, ML1114, ML1113, ML1122, ML1089, ML1424, ML0336, ML2352, ML1726, ML0669, ML0590 and ML1816 from M. leprae. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.;UniProt_AC=Q50046;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2057894	2058907	.	-	0	Locus=ML1706c;Name=ML1706c;Function=;Product=conserved hypothetical protein;Comments=ML1706c, len: 337 aa. Conserved hypothetical protein. Highly similar to proteins of undefined function from Streptomyces coelicolor TR:Q9Z586 (EMBL:AL035569) (331 aa), Fasta scores: E(): 0, 38.6% identity in 337 aa overlap and Mycobacterium tuberculosis Rv3015c TR:O53262 (EMBL:AL021287) (337 aa), Fasta scores: E(): 0, 78.3% identity in 337 aa overlap.;UniProt_AC=Q9CBR6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2346900	2347274	.	-	0	Locus=ML1960c;Name=rpsM;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S13 RPSM;Comments=ML1960c, len: 124 aa. Probable rpsM, 30S ribosomal protein S13. Similar to M. tuberculosis 30S ribosomal protein S13 rpsM Rv3460c SW:RS13_MYCTU (O06327) (124 aa), Fasta scores: E(): 0, 92.7% identity in 124 aa overlap. Contains Pfam match to entry PF00416 Ribosomal_S13, Ribosomal protein S13/S18. Contains PS00646 Ribosomal protein S13 signature.;UniProt_AC=Q9X7A1;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2539990	2540745	.	+	0	Locus=ML2137;Name=ML2137;Function=;Product=conserved hypothetical protein;Comments=ML2137, len: 251 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 27.4 kda protein Rv0883c SW:Y883_MYCTU (Q10545) fasta scores: E(): 0, 79.4% in 253 aa, and to Streptomyces coelicolor hypothetical 39.0 kda protein TR:O50529 (EMBL:AL009204) fasta scores: E(): 2.2e-19, 36.0% in 247 aa.;UniProt_AC=O33061;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2870659	2871516	.	-	0	Locus=ML2400c;Name=ML2400c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2400c, len: 285 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis putative transmembrane protein Rv1072 or MTV017.25 TR:O53420 (EMBL:AL021897) (278 aa) fasta scores: E(): 0, 77.5% identity in 285 aa, and to Streptomyces griseus transfer RNA-leu TR:Q54192 (EMBL:M80628) (293 aa) fasta scores: E(): 4.3e-27, 40.0% identity in 300 aa. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CB64;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2554752	2555276	.	+	0	Locus=ML2151;Name=ML2151;Function=;Product=conserved hypothetical protein;Comments=ML2151, len: 174 aa. Conserved hypothetical protein. Similar to C-terminus of Mycobacterium tuberculosis rpfA, resuscitation-promoting factor TR:O53879 (EMBL:AL022004) fasta scores: E(): 4.8e-29, 63.0% in 200 aa. Also similar to ML0240 and ML2030 from M. leprae. ;UniProt_AC=O33049;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2418627	2419610	.	+	0	Locus=ML2028;Name=fbpB;Function=INVOLVED IN CELL WALL MYCOLOYLATION. PROTEINS OF THE ANTIGEN 85 COMPLEX ARE RESPONSIBLE FOR THE HIGH AFFINITY OF MYCOBACTERIA TO FIBRONECTIN. POSSESSES A MYCOLYLTRANSFERASE ACTIVITY REQUIRED FOR THE BIOGENESIS OF TREHALOSE DIMYCOLATE (CORD FACTOR), A DOMINANT STRUCTURE NECESSARY FOR MAINTAINING CELL WALL INTEGRITY.;Product=SECRETED ANTIGEN 85-B FBPB (85B) (ANTIGEN 85 COMPLEX B) (MYCOLYL TRANSFERASE 85B) (FIBRONECTIN-BINDING PROTEIN B) (EXTRACELLULAR ALPHA-ANTIGEN);Comments=ML2028, len: 327 aa. Probable fbpB, secreted antigen (85A), mycolyltransferase (EC 2.3.1.-). Similar to Mycobacterium kansasii antigen 85-B precursor SW:A85B_MYCKA (P21160) fasta scores: E(): 0, 85.8% in 324 aa, and to Mycobacterium avium antigen 85-B precursor SW:A85B_MYCAV (Q06947) fasta scores: E(): 0, 81.2% in 329 aa and  P31952|A85B_MYCTU|Rv1886c Antigen 85-B precursor (85B) from M. tuberculosis (325 aa), fasta scores: E(): 1.6e-115, (83.025% identity in 324 aa overlap). Also similar to ML0097, ML2655 and ML0098 from M. leprae. Contains Pfam match to entry PF00756 Esterase, Putative esterase.;UniProt_AC=P31951;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2489138	2490052	.	-	0	Locus=ML2093c;Name=pstA1;Function=;Product=PROBABLE PHOSPHATE-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER PSTA1;Comments=ML2093c, len: 304 aa. Probable pstA1, phosphate-transport integral membrane ABC transporter. Similar to Mycobacterium tuberculosis phosphate transport system permease protein pstA1 TR:O86344 (EMBL:Z47983) fasta scores: E(): 0, 83.0% in 317 aa, and to Escherichia coli phosphate transport system permease protein pstc SW:PSTC_ECOLI (P07653) fasta scores: E(): 1.7e-30, 33.9% in 304 aa. Also similar to ML0930 a possible pseudogene similar to M. tuberculosis pstA1. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component.;UniProt_AC=Q50097;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2241072	2241914	.	-	0	Locus=ML1860c;Name=rplB;Function=;Product=PROBABLE 50S ribosomal protein L2 RPLB;Comments=ML1860c, len: 280 aa. Probable rplB, 50S ribosomal protein L2. Similar to M. tuberculosis 50S ribosomal protein L2 Rv0704 SW:RL2_MYCTU (P95052) (280 aa), Fasta scores: E(): 0, 92.1% identity in 280 aa overlap. Contains Pfam match to entry PF00181 Ribosomal_L2, Ribosomal Proteins L2. Contains PS00467 Ribosomal protein L2 signature.;UniProt_AC=O32984;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2005644	2006117	.	-	0	Locus=ML1664c;Name=ML1664c;Function=;Product=POSSIBLE METHYLTRANSFERASE (METHYLASE);Comments=ML1664c, len: 157 aa. Possible methyltransferase (EC 2.1.1.-). Similar to Mycobacterium tuberculosis Rv2966c TR:P95128 (EMBL:Z83018) (188 aa), Fasta scores: E(): 0, 72.9% identity in 155 aa overlap and Neisseria meningitidis possible DNA methylase TR:CAB83466 (EMBL:AL162752) (189 aa), Fasta scores: E(): 3.6e-07, 39.6% identity in 96 aa overlap. Contains PS00092 N-6 Adenine-specific DNA methylases signature.;UniProt_AC=Q9CBS5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2636012	2636686	.	-	0	Locus=ML2219c;Name=purQ;Function=;Product=PROBABLE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE I PURG (FGAM SYNTHASE I);Comments=ML2219c, len: 224 aa. Probable purQ, phosphoribosylformylglycinamidine synthase I (EC 6.3.5.3). Similar to Mycobacterium tuberculosis putative phosphoribosylformylglycinamidine synthase I Rv0788 OR MTCY369.32 TR:P71841 (EMBL:Z80226) fasta scores: E(): 0, 88.7% identity in 222 aa, and to Bacillus subtilis phosphoribosylformylglycinamidine synthase I PURQ SW:PURQ_BACSU (P12041) fasta scores: E(): 0, 47.2% identity in 214 aa. Contains PS00442 Glutamine amidotransferases class-I active site.;UniProt_AC=O05755,O05756;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2824110	2824895	.	-	0	Locus=ML2359c;Name=tesA;Function=;Product=PROBABLE THIOESTERASE TESA;Comments=ML2359c, len: 261 aa. Probable tesA, thioesterase (EC 3.1.2.-). Similar to several thioesterases associated with macrolide anitbiotic production e.g. Streptomyces griseus probable cadicidin biosynthesis thioesterase SW:PABT_STRGR (P33586) (361 aa) fasta scores: E(): 4.9e-24, 34.4% identity in 221 aa. Also similar to Mycobacterium tuberculosis probable thioesterase Rv2928 SW:YT28_MYCTU (Q10974) (261 aa) fasta scores: E(): 0, 74.7% identity in 249 aa. Contains Pfam match to entry PF00975 Thioesterase, Thioesterase domain.;UniProt_AC=Q9Z5K4;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2468743	2469231	.	-	0	Locus=ML2076c;Name=ML2076c;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN CFP17 HOMOLOG;Comments=ML2076c, len: 162 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 17.3 kda protein Rv1827 SW:YI27_MYCTU (Q50606) (162 aa), fasta scores: E(): 0, 87.0% in 161 aa, and to Streptomyces coelicolor hypothetical 28.1 kda protein TR:CAB88880 (EMBL:AL353861) fasta scores: E(): 1.9e-25, 54.6% in 141 aa. Contains Pfam match to entry PF00498 FHA, FHA domain.;UniProt_AC=O32919;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2603585	2604253	.	+	0	Locus=ML2188;Name=phoY2;Function=;Product=PROBABLE PHOSPHATE-TRANSPORT SYSTEM TRANSCRIPTIONAL REGULATORY PROTEIN PHOY2;Comments=ML2188, len: 222 aa. Probable phoY2, phosphate-transport system regulatory protein. Similar to Mycobacterium tuberculosis phosphate transport system regulatory protein Rv0821c TR:O53833 (EMBL:AL022004) fasta scores: E(): 0, 93.0% in 213 aa, and to O07167|PHU1_MYCTU|Rv3301c Phosphate transport system regulatory protein (221 aa), fasta scores: E(): 9.9e-58, (61.468% identity in 218 aa overlap) and Rhizobium meliloti phosphate transport system regulatory protein SW:PHOU_RHIME (Q52989) fasta scores: E(): 1.5e-15, 30.1% in 216 aa. Also similar to ML0401c a possible pseudogene similar to M. tuberculosis phoY2.;UniProt_AC=Q50047;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2880048	2881031	.	-	0	Locus=ML2409c;Name=ccsA;Function=;Product=POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCSA;Comments=ML2409c, len: 327 aa. Possible ccsA, cytochrome C-type biogenesis protein, integral membrane protein. Similar to many cytochrome C biogenesis proteins including Mycobacterium tuberculosis Rv0529 TR:O06395 (EMBL:Z95558) (324 aa) fasta scores: E(): 0, 83.2% identity in 327 aa, and to Guillardia theta  CcsA SW:CCSA_GUITH (P22554) (301 aa) fasta scores: E(): 5.5e-16, 35.6% identity in 261 aa. Contains a possible N-terminal signal sequence and multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01578 CytC_asm, Cytochrome C assembly protein.;UniProt_AC=Q49822;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2059823	2060899	.	-	0	Locus=ML1707c;Name=trmU;Function=;Product=probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase TrmU;Comments=ML1707c, len: 358 aa. Probable trmU, tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61). Highly similar to many proposed tRNA (5-methylaminomethyl-2-thiouridylate) -methyltransferases including: Escherichia coli SW:TRMU_ECOLI (P25745) (368 aa), Fasta scores: E(): 0, 35.6% identity in 362 aa overlap and Mycobacterium tuberculosis Rv3024c SW:TRMU_MYCTU (O53271) (367 aa), Fasta scores: E(): 0, 85.2% identity in 357 aa overlap.;UniProt_AC=O33099;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1914874	1915431	.	-	0	Locus=ML1590c;Name=frr;Function=;Product=RIBOSOME RECYCLING FACTOR FRR (RIBOSOME RELEASING FACTOR) (RRF);Comments=ML1590c, len: 185 aa. Probable frr, ribosome recycling factor. Highly similar to many ribosome releasing factors, involved in the release of ribosomes from messenger RNA at the termination of translation, e.g. Escherichia coli SW:RRF_ECOLI (P16174) (430 aa), BlastP Expect 9.8 and Mycobacterium tuberculosis Rv2882c SW:RRF_MYCTU (Q10794) (185 aa), Fasta scores: E(): 0, 90.8% identity in 185 aa overlap. Contains Pfam match to entry PF01765 RRF, Ribosome recycling factor.;UniProt_AC=O33046;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1915490	1916329	.	-	0	Locus=ML1591c;Name=pyrH;Function=;Product=PROBABLE URIDYLATE KINASE PYRH (UK) (URIDINE MONOPHOSPHATE KINASE) (UMP KINASE);Comments=ML1591c, len: 279 aa. Probable pyrH, uridylate kinase uridylate kinase (EC 2.7.4.-). Highly similar to many uridylate kinases including: Escherichia coli SW:PYRH_ECOLI (P29464) (240 aa), Fasta scores: E(): 0, 46.1% identity in 232 aa overlap and Mycobacterium tuberculosis Rv2883c SW:PYRH_MYCTU (Q10791) (261 aa), Fasta scores: E(): 0, 85.0% identity in 274 aa overlap. Contains Pfam match to entry PF00696 aakinase, Amino acid kinase family.;UniProt_AC=O33045;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1927810	1928130	.	-	0	Locus=ML1602c;Name=ML1602c;Function=;Product=hypothetical protein;Comments=ML1602c, len: 106 aa. Hypothetical unknown protein. Some similarity to Nikkomycin biosynthesis proteins e.g. Q93TU9 Nikkomycin biosynthesis protein SanS from Streptomyces ansochromogenes (424 aa), fasta scores: E(): 4.8e-13, (46.739% identity  in 92 aa overlap).;UniProt_AC=Q9CBT9;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1924851	1925744	.	-	0	Locus=ML1600c;Name=xerC;Function=;Product=PROBABLE INTEGRASE/RECOMBINASE XERC;Comments=ML1600c, len: 297 aa. Probable xerC, integrase/recombinase. Highly similar to many integrase/recombinases including: Escherichia coli XerD, involved in site-specific recombination of plasmid ColE1 and chromosome partitioning, SW:XERD_ECOLI (P21891) (298 aa), Fasta scores: E(): 0, 41.5% identity in 301 aa overlap and Mycobacterium tuberculosis Rv2894c SW:YS94_MYCTU (Q10815) (298 aa), Fasta scores: E(): 0, 85.1% identity in 296 aa overlap. Also similar to ML1365 from M. leprae. Contains Pfam match to entry PF00589 Phage_integrase, 'Phage' integrase family.;UniProt_AC=Q9CBU0;Is_Pseudogene=No;Functional_Category=insertion seqs and phages
AL450380.2	Mycobrowser_v2	CDS	2229646	2230299	.	-	0	Locus=ML1842c;Name=rpsE;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S5 RPSE;Comments=ML1842c, len: 217 aa. Probable rpsE, 30S ribosomal protein S5. Similar to M. tuberculosis 30S ribosomal protein S5 Rv0721 SW:RS5_MYCTU (P95069) (220 aa), Fasta scores: E(): 0, 87.9% identity in 190 aa overlap. Contains Pfam match to entry PF00333 Ribosomal_S5, Ribosomal protein S5. Contains PS00585 Ribosomal protein S5 signature.;UniProt_AC=O33000;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1939459	1939998	.	-	0	Locus=ML1616c;Name=rimM;Function=ESSENTIAL FOR EFFICIENT PROCESSING OF 16S RRNA. PROBABLY PART OF THE 30S SUBUNIT PRIOR TO OR DURING THE FINAL STEP IN THE PROCESSING OF 16S FREE 30S RIBOSOMAL SUBUNITS. IT COULD BE SOME ACCESSORY PROTEIN NEEDED FOR EFFICIENT ASSEMBLY OF THE 30S SUBUNIT. RIMM IS NEEDED IN A STEP PRIOR TO RBFA DURING THE MATURATION OF 16S RRNA. HAS AFFINITY FOR FREE RIBOSOMAL 30S SUBUNITS BUT NOT FOR 70S RIBOSOMES.;Product=PROBABLE 16S RRNA PROCESSING PROTEIN RIMM;Comments=ML1616c, len: 179 aa. Probable rimB, 16S rRNA processing protein. Highly similar to many 16s rRNA processing proteins including: Escherichia coli SW:RIMM_ECOLI (P21504) (182 aa), Fasta scores: E(): 2.8e-10, 30.6% identity in 183 aa overlap and Mycobacterium tuberculosis Rv2907c SW:RIMM_MYCTU (Q10824) (176 aa), Fasta scores: E(): 0, 73.1% identity in 175 aa overlap. Contains Pfam match to entry PF01782 RimM, RimM.;UniProt_AC=O33016;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1935445	1936167	.	-	0	Locus=ML1611c;Name=rnhB;Function=;Product=PROBABLE RIBONUCLEASE HII PROTEIN RNHB (RNASE HII);Comments=ML1611c, len: 240 aa. Probable rnhB, ribonuclease HII protein (EC 3.1.26.4). Highly similar to many ribonucleases including: Brucella melitensis ribonuclease HII and Mycobacterium tuberculosis ribonuclease HII Rv2902c SW:RNH2_MYCTU (Q10793) (264 aa), Fasta scores: E(): 0, 76.7% identity in 245 aa overlap. Contains Pfam match to entry PF01351 RNase_HII, Ribonuclease HII. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O33022;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1937119	1937460	.	-	0	Locus=ML1613c;Name=rplS;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L19 RPLS;Comments=ML1613c, len: 113 aa. Probable rplS, 50S ribosomal protein L19. Highly similar to many 50s ribosomal proteins (L19) including: Bacillus stearothermophilus SW:RL19_BACST (P30529) (116 aa), Fasta scores: E(): 5e-31, 70.8% identity in 106 aa overlap and Mycobacterium tuberculosis Rv2904c SW:RL19_MYCTU (Q10792) (113 aa), Fasta scores: E(): 0, 93.8% identity in 113 aa overlap. Contains Pfam match to entry PF01245 Ribosomal_L19, Ribosomal protein L19. Contains PS01015 Ribosomal protein L19 signature.;UniProt_AC=O33020;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1940270	1940752	.	-	0	Locus=ML1618c;Name=rpsP;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S16 RPSP;Comments=ML1618c, len: 160 aa. Probable rpsP, 30S ribosomal protein S16. Highly similar to many 30s ribosomal proteins (S16) including: Bacillus subtilis SW:RS16_BACSU (P21474) (89 aa), Fasta scores: E(): 2.1e-10, 45.1% identity in 82 aa overlap and Mycobacterium tuberculosis Rv2909c SW:RS16_MYCTU (Q10795) (162 aa), Fasta scores: E(): 0, 82.5% identity in 160 aa overlap. Contains Pfam match to entry PF00886 Ribosomal_S16, Ribosomal protein S16. Contains PS00732 Ribosomal protein S16 signature.;UniProt_AC=O33014;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1962937	1964283	.	-	0	Locus=ML1631c;Name=glnA2;Function=;Product=PROBABLE GLUTAMINE SYNTHETASE GLNA2 (GLUTAMINE SYNTHASE) (GS-II);Comments=ML1631c, len: 448 aa. Probable glnA2, glutamine synthase class II (EC 6.3.1.2). Highly similar to many glutamine synthetases including: Bacillus subtilis SW:GLNA_BACSU (P12425) (443 aa), Fasta scores: E(): 0, 45.4% identity in 445 aa overlap and Mycobacterium tuberculosis Rv2222c SW:GLN2_MYCTU (Q10378) (446 aa), Fasta scores: E(): 0, 93.3% identity in 448 aa overlap. Also similar to ML0925 from M. leprae. Contains Pfam match to entry PF00120 gln-synt, Glutamine synthetase.;UniProt_AC=Q9CBT3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1126817	1126894	.	-	0	Locus=ML0958A;Name=ML0958A;Function=;Product=DNA-binding protein, putative(pseudogene);Comments=ML0958A, len:77. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.002 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1974017	1975132	.	-	0	Locus=ML1637c;Name=ML1637c;Function=;Product=conserved hypothetical protein;Comments=ML1637c, len: 371 aa.  Conserved hypothetical protein. HIghly similar to Mycobacterium tuberculosis hypothetical protein Rv2228c SW:YM28_MYCTU (Q10512) (364 aa), Fasta scores: E(): 0, 76.8% identity in 371 aa overlap. The N-terminus is similar to several ribonucleases e.g. Escherichia coli ribonuclease HI (EC 3.1.26.4) SW:RNH_ECOLI (P00647) (430 aa), BlastP Expect 8.7. The C-terminus is similar to many proteins belonging to the phosphoglycerate mutase family e.g. Escherichia coli SW:COBC_ECOLI (P52086) (430 aa), BlastP Expect 8.7. Contains Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase family.;UniProt_AC=O69483;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1994536	1994883	.	+	0	Locus=ML1654;Name=acpM;Function=;Product=MEROMYCOLATE EXTENSION ACYL CARRIER PROTEIN ACPM;Comments=ML1654, len: 115 aa. Probable acpM, meromycolate extension acyl carrier protein. Highly similar to many acyl carrier proteins involved in fatty acid biosynthesis including: Myxococcus xanthus SW:ACP_MYXXA (P80921) (78 aa), Fasta scores: E(): 6.1e-13, 59.5% identity in 74 aa overlap and Mycobacterium tuberculosis Rv2244 SW:ACP_MYCTU (Q10500) (115 aa), Fasta scores: E(): 0, 94.7% identity in 113 aa overlap. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site.;UniProt_AC=O69475;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1993522	1994436	.	+	0	Locus=ML1653;Name=fabD;Function=;Product=MALONYL CoA-ACYL CARRIER PROTEIN TRANSACYLASE FABD (Malonyl CoA:AcpM acyltransferase) (MCT);Comments=ML1653, len: 304 aa. Probable fabD, malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39). Similar to many malonyl CoA-acyl carrier protein transacylases involved in fatty acid biosynthesis, including: Salmonella typhimurium SW:FABD_SALTY (O85140) (308 aa), Fasta scores: E(): 1.6e-19, 32.7% identity in 303 aa overlap and Mycobacterium tuberculosis Rv2243 SW:FABD_MYCTU (Q10501) (302 aa), Fasta scores: E(): 0, 82.2% identity in 304 aa overlap. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain.;UniProt_AC=O69476;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1992067	1993311	.	+	0	Locus=ML1652;Name=ML1652;Function=;Product=conserved hypothetical protein;Comments=ML1652, len: 414 aa. Conserved hypothetical protein. Highly similar to proteins of unknown function from Streptomyces coelicolor TR:Q9RDP8 (EMBL:AL133423) (401 aa), Fasta scores: E(): 4.3e-26, 42.0% identity in 383 aa overlap and Mycobacterium tuberculosis Rv2242 TR:YM42_MYCTU. Contains a probable helix-turn-helix motif at aa 359-380 (Score 1390, SD +3.92);UniProt_AC=O69477;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2204733	2205086	.	-	0	Locus=ML1821c;Name=ML1821c;Function=;Product=conserved hypothetical protein;Comments=ML1821c, len: 117 aa. Conserved hypothetical protein. Similar to the C-terminal region  of Q8GE87 Hypothetical protein from M. avium (186 aa), fasta scores: E(): 2.5e-09, (66.667% identity in 48 aa overlap). Homology to Q8GE87 continues downstream of this ORF in a different frame suggesting a possible frameshift. ;UniProt_AC=Q9CBL0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1136539	1136664	.	+	0	Locus=ML0967A;Name=ML0967A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0967A, len:125. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-04 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1996143	1997420	.	+	0	Locus=ML1656;Name=kasB;Function=INVOLVED IN FATTY ACID BIOSYNTHESIS (MYCOLIC ACIDS SYNTHESIS); INVOLVED IN MEROMYCOLATE EXTENSION. CATALYZES THE CONDENSATION REACTION OF FATTY ACID SYNTHESIS BY THE ADDITION TO AN ACYL ACCEPTOR OF TWO CARBONS FROM MALONYL-ACP [CATALYTIC ACTIVITY: ACYL-[ACYL-CARRIER PROTEIN] + MALONYL-[ACYL-CARRIER PROTEIN] = 3-OXOACYL-[ACYL-CARRIER PROTEIN] + [ACYL-CARRIER PROTEIN] + CO(2)].;Product=3-oxoacyl-[acyl-carrier-protein] synthase 2 KasB (BETA-KETOACYL-ACP SYNTHASE) (KAS I);Comments=ML1656, len: 425 aa. Probable kasB, 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41). Highly similar to many 3-oxoacyl-[acyl-carrier-protein] synthases II involved in fatty acid biosynthesis including: Escherichia coli SW:FABF_ECOLI (P39435) (412 aa), Fasta scores: E(): 0, 36.2% identity in 409 aa overlap and Mycobacterium tuberculosis Rv2246 SW:FAB2_MYCTU (Q10525) (438 aa), Fasta scores: E(): 0, 90.8% identity in 423 aa overlap. Also highly similar to the adjoining CDS ML1655. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=O69473;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2000901	2001617	.	-	0	Locus=ML1659c;Name=rnc;Function=;Product=PROBABLE RIBONUCLEASE III RNC (RNASE III);Comments=ML1659c, len: 238 aa. Probable rnc, Ribonuclease III (EC 3.1.26.3).  Highly similar to many ribonucleases involved in the digestion of double stranded RNA e.g. Escherichia coli SW:RNC_ECOLI (P05797) (226 aa), Fasta scores: E(): 1e-24, 41.8% identity in 213 aa overlap and Mycobacterium tuberculosis Rv2925c SW:RNC_MYCTU (Q10962) (240 aa), Fasta scores: E(): 0, 86.8% identity in 235 aa overlap. Contains Pfam match to entry PF00035 dsrm, Double-stranded RNA binding motif. Contains Pfam match to entry PF00636 Ribonuclease_3, RNase3 domain.. Contains PS00517 Ribonuclease III family signature.;UniProt_AC=O69469;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2019284	2019967	.	-	0	Locus=ML1675c;Name=ung;Function=;Product=PROBABLE URACIL-DNA GLYCOSYLASE UNG (UDG);Comments=ML1675c, len: 227 aa. Probable ung, uracil-DNA glycosylase (EC 3.2.2.-). Highly similar to many uracil-DNA glycosylases including: Streptococcus pneumoniae SW:UNG_STRPN (P23379) (123 aa), BlastP Expect 8.6 and Mycobacterium tuberculosis Rv2976c SW:UNG_MYCTU (P95119) (227 aa), Fasta scores: E(): 0, 88.5% identity in 227 aa overlap. Contains Pfam match to entry PF00315 UNG, Uracil-DNA glycosylase. Contains PS00130 Uracil-DNA glycosylase signature.;UniProt_AC=Q9CBS3;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2029540	2030136	.	-	0	Locus=ML1684c;Name=leuD;Function=;Product=PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT) LEUD (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI);Comments=ML1684c, len: 198 aa. Probable leuD, 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33). Highly similar to many 3-isopropylmalate dehydratase small subunits involved in leucine biosynthesis, including: Escherichia coli SW:LEUD_ECOLI (P30126) (201 aa), Fasta scores: E(): 1.2e-28, 42.1% identity in 197 aa overlap and Mycobacterium tuberculosis Rv2987c SW:LEUD_MYCTU (O53236) (198 aa), Fasta scores: E(): 0, 87.8% identity in 196 aa overlap. Contains Pfam match to entry PF00694 Aconitase_C, Aconitase C-terminal domain.;UniProt_AC=O33124;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2024688	2025338	.	+	0	Locus=ML1680;Name=ML1680;Function=;Product=conserved hypothetical protein;Comments=ML1680, len: 216 aa. Conserved hypothetical protein. Highly similar to several proteins of undefined function including: Mycobacterium tuberculosis Rv2983 TR:P95112 (EMBL:Z83018) (214 aa), Fasta scores: E(): 0, 79.1% identity in 215 aa overlap and Streptomyces coelicolor TR:Q9ZBS2 (EMBL:AL034447) (212 aa), Fasta scores: E(): 1.2e-17, 41.1% identity in 207 aa overlap. Contains Pfam match to entry PF01983 DUF121, Protein of unknown function.;UniProt_AC=O33128;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2035096	2035824	.	-	0	Locus=ML1689c;Name=ML1689c;Function=;Product=POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE);Comments=ML1689c, len: 242 aa. Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-). Similar to several putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerases including: Methanobacterium thermoautotrophicum TR:O27551 (EMBL:AE000911) (260 aa), Fasta scores: E(): 0, 51.9% identity in 216 aa overlap and Mycobacterium tuberculosis Rv2993c TR:O53242 (EMBL:AL021287) (239 aa), Fasta scores: E(): 0, 85.9% identity in 241 aa overlap. Contains Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family.;UniProt_AC=O33119;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2042727	2043728	.	-	0	Locus=ML1694c;Name=ilvC;Function=;Product=PROBABLE KETOL-ACID REDUCTOISOMERASE ILVC (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacil reductoisomerase);Comments=ML1694c, len: 333 aa. Probable ilvC, ketol-acid reductoisomerase (EC1.1.1.86 ). Highly similar to many ketol-acid reductoisomerases involved in valine and isoleucine biosynthesis, including: Mycobacterium avium SW:ILVC_MYCAV (Q59500) (333 aa), Fasta scores: E(): 0, 89.2% identity in 333 aa overlap and Mycobacterium tuberculosis Rv3001c SW:ILVC_MYCTU (O53248) (333 aa), Fasta scores: E(): 0, 86.2% identity in 333 aa overlap. Contains Pfam match to entry PF01450 IlvC, Acetohydroxy acid isomeroreductase.;UniProt_AC=O33114;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2050127	2051656	.	-	0	Locus=ML1700c;Name=gatB;Function=COMPONENT OF THE TRANSLATIONAL APPARATUS. FURNISHES A MEANS FOR FORMATION OF CORRECTLY CHARGED GLN-TRNA(GLN) THROUGH THE TRANSAMIDATION OF MISACYLATED GLU- TRNA(GLN) IN ORGANISMS WHICH LACK GLUTAMINYL-TRNA SYNTHETASE. THE REACTION TAKES PLACE IN THE PRESENCE OF GLUTAMINE AND ATP THROUGH AN ACTIVATED GAMMA-PHOSPHO-GLU-TRNA(GLN) [CATALYTIC ACTIVITY: ATP + L-GLUTAMYL-TRNA(GLN) + L-GLUTAMINE = ADP + PHOSPHATE + L-GLUTAMINYL-TRNA(GLN) + L-GLUTAMATE].;Product=PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT B) GATB (Glu-ADT SUBUNIT B);Comments=ML1700c, len: 509 aa. Probable gatB, glutamyl-tRNA(Gln) amidotransferase, subunit B (EC 6.3.5.-). Highly similar to many glutamyl-tRNA(Gln) amidotransferases (subunit B) including: Bacillus subtilis SW:GATB_BACSU (O30509) (269 aa), BlastP Expect 8.6 and Mycobacterium tuberculosis Rv3009c SW:GATB_MYCTU (O53256) (509 aa), Fasta scores: E(): 0, 88.4% identity in 509 aa overlap. Contains Pfam match to entry PF01162 PET112, PET112 family. Contains PS01234 PET112 family signature.;UniProt_AC=O33107;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2052005	2053036	.	-	0	Locus=ML1701c;Name=pfkA;Function=;Product=PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE);Comments=ML1701c, len: 343 aa. Probable pfkA, 6-phosphofructokinase (EC 2.7.1.11). Highly similar to many 6-phosphofructokinases including: Streptomyces coelicolor SW:K6PF_STRCO (O08333) (342 aa), Fasta scores: E(): 0, 56.5% identity in 345 aa overlap and Mycobacterium tuberculosis Rv3010c SW:K6PF_MYCTU (O53257) (343 aa), Fasta scores: E(): 0, 90.4% identity in 343 aa overlap. Contains 2 Pfam matches to entry PF00365 PFK, Phosphofructokinase. Contains PS00433 Phosphofructokinase signature.;UniProt_AC=O33106;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2188475	2189482	.	-	0	Locus=ML1808c;Name=ML1808c;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN;Comments=ML1808c, len: 335 aa. Probable membrane protein. Similar to M. tuberculosis Rv1481 SW:YE81_MYCTU (P71762) (335 aa), Fasta scores: E(): 0, 91.0% identity in 335 aa overlap. Contains Pfam match to entry PF00092 vwa, von Willebrand factor type A domain. Similar to ML0701 from M. leprae.;UniProt_AC=Q9CBL9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2055751	2057835	.	-	0	Locus=ML1705c;Name=ligA;Function=THIS PROTEIN CATALYZES THE FORMATION OF PHOSPHODIESTER LINKAGES BETWEEN 5'-PHOSPHORYL AND 3'-HYDROXYL GROUPS IN DOUBLE-STRANDED DNA USING NAD AS A COENZYME AND AS THE ENERGY SOURCE FOR THE REACTION. IT IS ESSENTIAL FOR DNA REPLICATION AND REPAIR OF DAMAGED DNA [CATALYTIC ACTIVITY: NAD(+) + (DEOXYRIBONUCLEOTIDE)(N) + (DEOXYRIBONUCLEOTIDE)(M) = AMP + NICOTINAMIDE NUCLEOTIDE + (DEOXYRIBONUCLEOTIDE)(N+M)].;Product=PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]);Comments=ML1705c, len: 694 aa. Probable ligA, DNA ligase (EC 6.5.1.2). Highly similar to many DNA ligases essential for DNA replication and repair, including: DNLJ_ECOLI and Mycobacterium tuberculosis Rv3014c SW:DNLJ_MYCTU (O53261) (691 aa), Fasta scores: E(): 0, 84.7% identity in 687 aa overlap. Contains Pfam match to entry PF01653 DNA_ligase_N, NAD-dependent DNA ligase. Contains Pfam match to entry PF00533 BRCT, BRCA1 C Terminus (BRCT) domain. Contains PS01055 NAD-dependent DNA ligase signature 1.;UniProt_AC=O33102;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2080798	2081556	.	-	0	Locus=ML1724c;Name=echA17;Function=;Product=PROBABLE ENOYL-CoA HYDRATASE ECHA17 (CROTONASE) (UNSATURED ACYL-CoA HYDRATASE) (ENOYL HYDRASE);Comments=ML1724c, len: 252 aa. Probable echA17, enoyl-CoA hydratase (EC 4.2.1.17). Similar to several proposed enoyl-CoA hydratases including: Rhizobium meliloti SW:ECHH_RHIME (Q52995) (257 aa), Fasta scores: E(): 1.8e-19, 34.7% identity in 225 aa overlap, Clostridium acetobutylicum SW:CRT_CLOAB (P52046) (261 aa), Fasta scores: E(): 1.7e-17, 27.9% identity in 240 aa overlap and Mycobacterium tuberculosis Rv3039c TR:O53286 (EMBL:AL021287) (254 aa), Fasta scores: E(): 0, 85.6% identity in 243 aa overlap. Also similar to ML2402 from M. leprae. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.;UniProt_AC=Q9CBQ8;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2086569	2087663	.	+	0	Locus=ML1729;Name=fecB;Function=;Product=PROBABLE FEIII-DICITRATE-BINDING PERIPLASMIC LIPOPROTEIN FECB;Comments=ML1729, len: 364 aa. Probable fecB, FeIII dicitrate-binding periplasmic lipoprotein. Highly similar to several proteins involved in iron transport including: Mycobacterium avium  FecB precursor TR:AAF73189 (EMBL:AF151098) (364 aa), Fasta scores: E(): 0, 67.4% identity in 362 aa overlap and Mycobacterium tuberculosis Rv3044 TR:O53291 (EMBL:AL021287) (359 aa), Fasta scores: E(): 0, 75.6% identity in 357 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains Pfam match to entry PF01497 Peripla_BP_2, Periplasmic binding protein. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CBQ4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2158331	2159152	.	-	0	Locus=ML1782c;Name=ML1782c;Function=;Product=conserved hypothetical protein;Comments=ML1782c, len: 273 aa. Conserved hypothetical protein. Similar to M. tuberculosis Rv2257c TR:O53531 (EMBL:AL021925) (272 aa), Fasta scores: E(): 0, 76.4% identity in 271 aa overlap, and to Streptomyces coelicolor SC4A7.08 TR:Q9RDQ4 (EMBL:AL133423) (273 aa), Fasta scores: E(): 0, 53.2% identity in 269 aa overlap.;UniProt_AC=Q9CBN4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2191853	2192578	.	-	0	Locus=ML1811c;Name=ML1811c;Function=;Product=HYPOTHETICAL INVASION PROTEIN;Comments=ML1811c, len: 241 aa. Hypothetical Invasion protein, possibly exported protein. Similar to M. tuberculosis Rv1478 TR:O53169 (EMBL:AL021184) (241 aa), Fasta scores: E(): 0, 77.1% identity in 240 aa overlap, and to Listeria innocua protein p60 precursor (invasion-associated protein) SW:P60_LISIN (Q01836) (481 aa), Fasta scores: E(): 4.2e-07, 31.0% identity in 200 aa overlap. Also similar to ML1812, ML1214 and ML0885 from M. leprae. Contains Pfam match to entry PF00877 NLPC_P60, NLP/P60 family.;UniProt_AC=Q9CBL6;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2174304	2174750	.	+	0	Locus=ML1795;Name=hsp18;Function=;Product=18 KDA antigen Hsp18 (HSP 16.7);Comments=ML1795, len: 148 aa. hsp18, 18 KDA antigen. Highly similar to other mycobacterial antigens e.g. 18K1_MYCIT|P46730 18 kDa antigen 1 from Mycobacterium intracellulare (149 aa), Fasta scores: E(): 0, (78.7% identity in 150 aa overlap), and small heat shock proteins e.g. HS18_STRAL|Q53595 hsp18 from  Streptomyces albus (143 aa), Fasta scores: E(): 4.1e-26, (55.0% identity in 140 aa overlap). Previously sequenced as 18KD_MYCLE|P12809 (148 aa), Fasta scores: E(): 0, 100.0% identity in 148 aa overlap. Contains Pfam match to entry PF00011 HSP20, Hsp20/alpha crystallin family. Belongs to the small heat shock protein (HSP20) family.;UniProt_AC=P12809;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2165627	2166004	.	-	0	Locus=ML1791c;Name=ML1791c;Function=;Product=conserved hypothetical protein;Comments=ML1791c, len: 125 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetical protein Rv1976c TR:O53977 (EMBL:AL022073) (135 aa), Fasta scores: E(): 3.5e-28, 65.3% identity in 124 aa overlap, and to Streptomyces coelicolor hypothetical protein SC1C3.03C TR:O69845 (EMBL:AL023702) (125 aa), Fasta scores: E(): 4.3e-06, 36.6% identity in 112 aa overlap. Note start changed since original submission.;UniProt_AC=Q9CBN1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2171519	2172727	.	+	0	Locus=ML1794;Name=ML1794;Function=;Product=Probable aminotransferase;Comments=ML1794, len: 402 aa. Probable aminotransferase (EC 2.6.1.-). Similar to M. tuberculosis predicted aminotransferase Rv2294 SW:YM94_MYCTU (Q50672) (407 aa), Fasta scores: E(): 0, 76.5% identity in 404 aa overlap, and to many others e.g. Escherichia coli MalY protein SW:MALY_ECOLI (P23256) (390 aa), Fasta scores: E(): 5.8e-27, 31.2% identity in 385 aa overlap. Also similar to ML2502 from M. leprae.;UniProt_AC=Q9CBM9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2184852	2185748	.	+	0	Locus=ML1804;Name=ML1804;Function=;Product=conserved hypothetical protein;Comments=ML1804, len: 298 aa. Conserved hypothetical protein. Similar to M. tuberculosis Rv1486c SW:YE86_MYCTU (P71766) (288 aa), Fasta scores: E(): 5.1e-25, 76.7% identity in 300 aa overlap, and to Mycobacterium avium hypothetical protein MAV321 SW:YE86_MYCAV (O07402) (320 aa), Fasta scores: E(): 0, 62.9% identity in 315 aa overlap.;UniProt_AC=Q9CBM3;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2177910	2180186	.	-	0	Locus=ML1799c;Name=mutB;Function=;Product=PROBABLE METHYLMALONYL-CoA MUTASE LARGE SUBUNIT MUTB (MCM);Comments=ML1799c, len: 758 aa. Probable mutB, methylmalonyl-CoA mutase (EC 5.4.99.2). Similar to M. tuberculosis mutB Rv1493 SW:MUTB_MYCTU (P71774) (750 aa), Fasta scores: E(): 0, 88.9% identity in 748 aa overlap, and many other methylmalonyl-CoA mutase alpha-subunit e.g. Streptomyces cinnamonensis SW:MUTB_STRCM (Q05065) (733 aa), Fasta scores: E(): 0, 74.7% identity in 726 aa overlap. Also similar to ML1800. Contains Pfam match to entry PF01642 MM_CoA_mutase, Methylmalonyl-CoA mutase. Contains PS00544 Methylmalonyl-CoA mutase signature.;UniProt_AC=Q9CBM7;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2185785	2186795	.	-	0	Locus=ML1805c;Name=hemZ;Function=;Product=FERROCHELATASE HEMZ (PROTOHEME FERRO-LYASE) (HEME SYNTHETASE);Comments=ML1805c, len: 336 aa. Probable hemZ, ferrochelatase (EC 4.99.1.1). Similar to M. tuberculosis hemZ Rv1485 SW:HEMZ_MYCTU (P71765) (344 aa), Fasta scores: E(): 0, 76.8% identity in 336 aa overlap, and to many others e.g. Propionibacterium freudenreichii shermanii ferrochelatase SW:HEMZ_PROFR (P72183) (352 aa), Fasta scores: E(): 0, 38.9% identity in 311 aa overlap. Contains Pfam match to entry PF00762 Ferrochelatase, Ferrochelatase. Contains PS00534 Ferrochelatase signature.;UniProt_AC=Q9CBM2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2192605	2194044	.	-	0	Locus=ML1812c;Name=ML1812c;Function=;Product=HYPOTHETICAL INVASION PROTEIN;Comments=ML1812c, len: 479 aa. Hypothetical Invasion protein. Possibly exported protein with unusually long signal sequence. Similar to M. tuberculosis Rv1477 TR:O53168 (EMBL:AL021184) (472 aa), Fasta scores: E(): 0, 78.8% identity in 480 aa overlap and to Listeria innocua protein p60 precursor (invasion-associated protein) SW:P60_LISMO (P21171) (484 aa), Fasta scores: E(): 1e-06, 23.8% identity in 491 aa overlap. Also similar to ML1811, ML1214 and ML0885 from M. leprae. Contains Pfam match to entry PF00877 NLPC_P60, NLP/P60 family.;UniProt_AC=Q9CBL5;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2231936	2232499	.	-	0	Locus=ML1847c;Name=rplE;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L5 RPLE;Comments=ML1847c, len: 187 aa. Probable rplE, 50S ribosomal protein L5. Similar to M. tuberculosis 50S ribosomal protein L5 Rv0716 SW:RL5_MYCTU (P95064) (187 aa), Fasta scores: E(): 0, 91.4% identity in 187 aa overlap. Contains Pfam match to entry PF00281 Ribosomal_L5, Ribosomal protein L5. Contains Pfam match to entry PF00673 Ribosomal_L5_C, ribosomal L5P family C-terminus.;UniProt_AC=O32995;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2230699	2231238	.	-	0	Locus=ML1844c;Name=rplF;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L6 RPLF;Comments=ML1844c, len: 179 aa. Probable rplF, 50S ribosomal protein L6. Similar to M. tuberculosis 50S ribosomal protein L6 Rv0719 SW:RL6_MYCTU (P95067) (179 aa), Fasta scores: E(): 0, 90.5% identity in 179 aa overlap. Contains Pfam match to entry PF00347 Ribosomal_L6, Ribosomal protein L6. Contains PS00525 Ribosomal protein L6 signature 1.;UniProt_AC=O32998;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2232500	2232817	.	-	0	Locus=ML1848c;Name=rplX;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L24 RPLX;Comments=ML1848c, len: 105 aa. Probable rplX, 50S ribosomal protein L24. Similar to M. tuberculosis 50S ribosomal protein L24 Rv0715 SW:RL24_MYCTU (P95063) (105 aa), Fasta scores: E(): 0, 93.3% identity in 105 aa overlap. Contains Pfam match to entry PF00467 Ribosomal_L24, KOW motif. Contains PS01108 Ribosomal protein L24 signature.;UniProt_AC=O32994;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2238978	2239394	.	-	0	Locus=ML1856c;Name=rplP;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L16 RPLP;Comments=ML1856c, len: 138 aa. Probable rplP, 50S ribosomal protein L16. Similar to M. tuberculosis 50S ribosomal protein L16 Rv0708 SW:RL16_MYCTU (P95056) (138 aa), Fasta scores: E(): 0, 96.4% identity in 138 aa overlap. Contains Pfam match to entry PF00252 Ribosomal_L16, Ribosomal protein L16. Contains PS00701 Ribosomal protein L16 signature 2.;UniProt_AC=O32988;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2241944	2242246	.	-	0	Locus=ML1861c;Name=rplW;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L23 RPLW;Comments=ML1861c, len: 100 aa. Probable rplW, 50S ribosomal protein L23. Similar to M. tuberculosis 50S ribosomal protein L23 Rv0703 SW:RL23_MYCTU (P95051) (100 aa), Fasta scores: E(): 0, 85.0% identity in 100 aa overlap. Contains Pfam match to entry PF00276 Ribosomal_L23, Ribosomal protein L23. Contains PS00050 Ribosomal protein L23 signature.;UniProt_AC=O32983;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2238736	2238981	.	-	0	Locus=ML1855c;Name=rpmC;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L29 RPMC;Comments=ML1855c, len: 81 aa. Probable rpmC, 50S ribosomal protein L29. Similar to M. tuberculosis 50S ribosomal protein L29 Rv0709 SW:RL29_MYCTU (P95057) (77 aa), Fasta scores: E(): 2.5e-25, 91.9% identity in 74 aa overlap. Contains Pfam match to entry PF00831 Ribosomal_L29, Ribosomal L29 protein.;UniProt_AC=O32989;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2239398	2240243	.	-	0	Locus=ML1857c;Name=rpsC;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S3 RPSC;Comments=ML1857c, len: 281 aa. Probable rpsC, 30S ribosomal protein S3. Similar to M. tuberculosis 30S ribosomal protein S3 Rv0707 SW:RS3_MYCTU (P95055) (273 aa), Fasta scores: E(): 0, 95.0% identity in 259 aa overlap. Contains Pfam match to entry PF00417 Ribosomal_S3_N, Ribosomal protein S3, N-terminal domain.. Contains Pfam match to entry PF00013 KH-domain, KH domain. Contains Pfam match to entry PF00189 Ribosomal_S3_C, Ribosomal protein S3, C-terminal domain. Contains PS00548 Ribosomal protein S3 signature.;UniProt_AC=O32987;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2238356	2238739	.	-	0	Locus=ML1854c;Name=rpsQ;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S17 RPSQ;Comments=ML1854c, len: 127 aa. Probable rpsQ, 30S ribosomal protein S17. Similar to M. tuberculosis 30S ribosomal protein S17 Rv0710 SW:RS17_MYCTU (P95058) (136 aa), Fasta scores: E(): 1.5e-29, 77.2% identity in 136 aa overlap. Contains Pfam match to entry PF00366 Ribosomal_S17, Ribosomal protein S17. Contains PS00056 Ribosomal protein S17 signature.;UniProt_AC=O32990;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2240767	2241048	.	-	0	Locus=ML1859c;Name=rpsS;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S19 RPSS;Comments=ML1859c, len: 93 aa. Probable rpsS, 30S ribosomal protein S19. Similar to M. tuberculosis 30S ribosomal protein S19 Rv0705 SW:RS19_MYCTU (P48947) (93 aa), Fasta scores: E(): 0, 96.8% identity in 93 aa overlap. Contains Pfam match to entry PF00203 Ribosomal_S19, Ribosomal protein S19. Contains PS00323 Ribosomal protein S19 signature.;UniProt_AC=O32985;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2259295	2259765	.	-	0	Locus=ML1879c;Name=rpsG;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S7 RPSG;Comments=ML1879c, len: 156 aa. Probable rpsG, 30S ribosomal protein S7. Similar to Mycobacterium tuberculosis 30s ribosomal protein S7 rpsG or rps7 or Rv0683 or MTV040.11 SW:RS7_MYCTU (P41194) (155 aa) fasta scores: E(): 0, 98.1% identity in 155 aa and to Mycobacterium smegmatis 30s ribosomal protein S7 rpsG SW:RS7_MYCSM (P41193) (155 aa) fasta scores: E(): 0, 95.5% identity in 155 aa. Previously sequenced as SW:RS7_MYCLE (P30764). Contains Pfam match to entry PF00177 Ribosomal_S7, Ribosomal protein S7p/S5e. Contains PS00052 Ribosomal protein S7 signature.;UniProt_AC=P30764;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2259765	2260139	.	-	0	Locus=ML1880c;Name=rpsL;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S12 RPSL;Comments=ML1880c, len: 124 aa. Probable rpsL, 30S ribosomal protein S12. Similar to M. tuberculosis 30S ribosomal protein S12 RPS12 SW:RS12_MYCTU (P41196) (124 aa), Fasta scores: E(): 0, 97.6% identity in 123 aa overlap. Contains Pfam match to entry PF00164 Ribosomal_S12, Ribosomal protein S12. Contains PS00055 Ribosomal protein S12 signature.;UniProt_AC=P30766;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2282295	2283641	.	+	0	Locus=ML1898;Name=ML1898;Function=;Product=conserved hypothetical protein;Comments=ML1898, len: 448 aa. Conserved hypothetical protein. Similar to M. tuberculosis conserved hypothetical protein Rv0647c SW:Y647_MYCTU (P96936) (488 aa), Fasta scores: E(): 0, 85.3% identity in 448 aa overlap, and to others e.g. Synechocystis sp. SW:YH70_SYNY3 (P73627) (585 aa), Fasta scores: E(): 0, 30.9% identity in 401 aa overlap. Also similar to ML0640 from M. leprae.;UniProt_AC=Q9CBK6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1139611	1139733	.	-	0	Locus=ML0970A;Name=ML0970A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0970A, len:122. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-13 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2291611	2292297	.	-	0	Locus=ML1906c;Name=nusG;Function=;Product=PROBABLE TRANSCRIPTION ANTITERMINATION PROTEIN NUSG;Comments=ML1906c, len: 228 aa. Probable nusG, transcription antitermination protein. Similar to M. tuberculosis transcription antitermination protein nusG Rv0639 TR:P96930 (EMBL:Z92772) (238 aa), Fasta scores: E(): 0, 93.4% identity in 211 aa overlap, and to many others e.g. Streptomyces griseus. Contains PS01014 Transcription termination factor nusG signature.;UniProt_AC=Q9CBK0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2291155	2291583	.	-	0	Locus=ML1905c;Name=rplK;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L11 RPLK;Comments=ML1905c, len: 142 aa. Probable rplK, 50S ribosomal protein L11. Similar to M. tuberculosis 50S ribosomal protein L11 Rv0640 SW:RL11_MYCTU (P96931) (142 aa), Fasta scores: E(): 0, 92.3% identity in 142 aa overlap. Contains Pfam match to entry PF00298 Ribosomal_L11, Ribosomal protein L11. Contains PS00359 Ribosomal protein L11 signature.;UniProt_AC=Q9CBK1;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2293151	2293651	.	-	0	Locus=ML1908c;Name=ML1908c;Function=;Product=conserved hypothetical protein;Comments=ML1908c, len: 166 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetical protein Rv0637 TR:P96928 (EMBL:Z92772) (166 aa), Fasta scores: E(): 0, 88.6% identity in 166 aa overlap, and to others e.g. Streptomyces coelicolor SCD82.07 TR:CAB77410 (EMBL:AL160431) (150 aa), Fasta scores: E(): 4.7e-11, 29.3% identity in 150 aa overlap. Also similar to ML1910 and ML2425 from M. leprae.;UniProt_AC=Q9CBJ8;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2312099	2312407	.	-	0	Locus=ML1927c;Name=ML1927c;Function=;Product=conserved hypothetical protein;Comments=ML1927c, len: 102 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetical protein Rv0430 TR:P96276 (EMBL:Z84724) (102 aa), Fasta scores: E(): 0, 93.1% identity in 102 aa overlap, and to Streptomyces coelicolor hypothetical protein SCD95A.20 TR:CAB93047 (EMBL:AL357432) (84 aa), Fasta scores: E(): 4.1e-11, 52.8% identity in 72 aa overlap.;UniProt_AC=Q9CBI4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2303412	2304305	.	+	0	Locus=ML1920;Name=mutY;Function=;Product=PROBABLE ADENINE GLYCOSYLASE MUTY;Comments=ML1920, len: 297 aa. Probable mutY, DNA glycosylase (EC 3.2.2.-). Similar to M. tuberculosis probable DNA glycosylase Rv3589 TR:O53574 (EMBL:AL022075) (304 aa), Fasta scores: E(): 0, 74.9% identity in 303 aa overlap, and to many others e.g. Escherichia coli A/G-specific adenine glycosylase mutY SW:MUTY_ECOLI (P17802) (350 aa), Fasta scores: E(): 1.8e-21, 33.2% identity in 244 aa overlap. Also similar to ML2301 from M. leprae. Contains Pfam match to entry PF00730 Endonuclease_3, Endonuclease III.;UniProt_AC=Q9CBJ0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2336696	2337571	.	-	0	Locus=ML1950c;Name=ML1950c;Function=;Product=POSSIBLE GLYCOSYL HYDROLASE ;Comments=ML1950c, len: 291 aa. Possible glycosyl hydrolase (EC 3.-.-.-), possibly deacetylase or esterase. Similar to M. tuberculosis Rv1096 TR:O53444 (EMBL:AL021897) glycosyl hydrolase (291 aa), Fasta scores: E(): 0, 81.3% identity in 289 aa overlap, and to Streptomyces lividans acetylxylan esterase precursor TR:Q54413 (EMBL:M64552) (335 aa), Fasta scores: E(): 2.8e-18, 31.8% identity in 236 aa overlap. Also similar to ML2649 from M. leprae. Contains Pfam match to entry PF01522 Polysac_deacet, Polysaccharide deacetylase.;UniProt_AC=Q9X791;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1150655	1151052	.	+	0	Locus=ML0983A;Name=ML0983A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0983A, len:397. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-15 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2341570	2342508	.	+	0	Locus=ML1954;Name=coaA;Function=;Product=Probable pantothenate kinase CoaA (Pantothenic acid kinase);Comments=ML1954, len: 312 aa. Probable coaA, pantothenate kinase (EC 2.7.1.33). Similar to M. tuberculosis pantothenate kinase coaA Rv1092c SW:COAA_MYCTU (O53440) (312 aa), Fasta scores: E(): 0, 93.6% identity in 312 aa overlap, and to many others e.g. Escherichia coli pantothenate kinase SW:COAA_ECOLI (P15044) (316 aa), Fasta scores: E(): 0, 53.1% identity in 311 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9X795;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2343336	2344085	.	-	0	Locus=ML1955c;Name=truA;Function=;Product=PROBABLE TRNA PSEUDOURIDINE SYNTHASE A TRUA (PSEUDOURIDYLATE SYNTHASE I) (PSEUDOURIDINE SYNTHASE I) (URACIL HYDROLYASE);Comments=ML1955c, len: 249 aa. Probable truA, tRNA pseudouridine synthase A (EC 4.2.1.70). Similar to M. tuberculosis probable pseudouridylate synthase truA Rv3455c SW:TRUA_MYCTU (Z95390) (256 aa), Fasta scores: E(): 0, 77.2% identity in 246 aa overlap, and to many others e.g Pseudomonas aeruginosa tRNA pseudouridine synthase A SW:TRUA_PSEAE (O87016) (285 aa), Fasta scores: E(): 4.2e-16, 34.3% identity in 242 aa overlap. Contains Pfam match to entry PF01416 PseudoU_synth_1, tRNA pseudouridine synthase.;UniProt_AC=Q9X796;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2347604	2347825	.	-	0	Locus=ML1962c;Name=infA;Function=;Product=PROBABLE TRANSLATION INITIATION FACTOR IF-1 INFA;Comments=ML1962c, len: 73 aa. Probable infA, translation initiation factor IF-1. Similar to M. tuberculosis initiation factor IF-1 infA Rv3462c SW:IF1_MYCTU (P45957) (72 aa), Fasta scores: E(): 9.6e-30, 100.0% identity in 72 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain.;UniProt_AC=P0A5H7;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2345841	2346446	.	-	0	Locus=ML1958c;Name=rpsD;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S4 RPSD;Comments=ML1958c, len: 201 aa. Probable rpsD, 30S ribosomal protein S4. Similar to M. tuberculosis 30S ribosomal protein S4 rpsD Rv3458c SW:RS4_MYCTU (O06325) (201 aa), Fasta scores: E(): 0, 93.5% identity in 201 aa overlap. Contains Pfam match to entry PF00163 Ribosomal_S4, Ribosomal protein S4/S9 N-terminal domain. Contains Pfam match to entry PF01479 S4, S4 domain. Contains PS00632 Ribosomal protein S4 signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9X799;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2346480	2346896	.	-	0	Locus=ML1959c;Name=rpsK;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S11 RPSK;Comments=ML1959c, len: 138 aa. Probable rpsK, 30S ribosomal protein S11. Similar to M. tuberculosis 30S ribosomal protein S11 rpsK Rv3459c SW:RS11_MYCTU (O06326) (139 aa), Fasta scores: E(): 0, 89.9% identity in 139 aa overlap. Contains Pfam match to entry PF00411 Ribosomal_S11, Ribosomal protein S11. Contains PS00054 Ribosomal protein S11 signature.;UniProt_AC=Q9X7A0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2373434	2375734	.	+	0	Locus=ML1987;Name=ctpA;Function=;Product=PROBABLE CATION TRANSPORTER P-TYPE ATPASE A CTPA;Comments=ML1987, len: 766 aa. Probable ctpA, cation-transporter P-type ATPase A (EC 3.6.3.-). Similar to Mycobacterium tuberculosis cation-transporting P-type ATPase A ctpA or Rv0092 or MTCY251.11 SW:CTPA_MYCTU (Q10876) (761 aa) fasta scores: E(): 0, 77.2% identity in 715 aa. Previously sequenced as SW:CTPA_MYCLE (P46839). Also similar to ML0747 and ML2000 from M. leprae. Contains multiple possible membrane spanning hydrophobic domains and Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase. Contains PS00154 E1-E2 ATPases phosphorylation site.;UniProt_AC=P46839;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2380056	2380925	.	+	0	Locus=ML1992;Name=ML1992;Function=;Product=POSSIBLE OXIDOREDUCTASE;Comments=ML1992, len: 289 aa. Possible oxidoreductase. Similar to M. tuberculosis possible oxidoreductase Rv0097 SW:Y097_MYCTU (Q10893) (289 aa), Fasta scores: E(): 0, 76.4% identity in 288 aa overlap, and to Escherichia coli alpha-ketoglutarate-dependent taurine dioxygenase SW:TAUD_ECOLI (P37610) (282 aa), Fasta scores: E(): 2.6e-10, 24.5% identity in 278 aa overlap.;UniProt_AC=Q9CBG4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2383094	2383330	.	+	0	Locus=ML1995;Name=ML1995;Function=;Product=conserved hypothetical protein;Comments=ML1995, len: 78 aa. Conserved hypothetical protein. Similar to M. tuberculosis hypothetical protein Rv0100 SW:Y100_MYCTU (Q10895) (78 aa), Fasta scores: E(): 1.1e-18, 69.0% identity in 71 aa overlap. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site.;UniProt_AC=Q9CBG2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2387539	2388171	.	-	0	Locus=ML1997c;Name=ML1997c;Function=;Product=PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN;Comments=ML1997c, len: 210 aa. Probable conserved integral membrane protein. Similar to M. tuberculosis probable integral membrane protein Rv0970 SW:Y970_MYCTU (P71541) (210 aa), Fasta scores: E(): 0, 52.1% identity in 213 aa overlap, and to Streptomyces coelicolor putative integral membrane protein SCM2.15C. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CBG1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2383327	2387532	.	+	0	Locus=ML1996;Name=nrp;Function=;Product=POSSIBLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE);Comments=ML1996, len: 1401 aa. Possible nrp, peptide synthase. Similar in N-terminus to M. tuberculosis probable peptide synthetase nrp Rv0101 TR:Q10896 (EMBL:Z74410) (2512 aa), Fasta scores: E(): 0, 65.7% identity in 1089 aa overlap, and to e.g. Streptomyces sp streptothricin peptide synthase TR:O33743 (EMBL:Y10293) (481 aa), Fasta scores: E(): 5.6e-20, 31.2% identity in 382 aa overlap. Also similar to ML1051 and ML0243 from M. leprae. Similar to ML2665 a possible pseudogene similar to M. tuberculosis nrp. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q50177;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2378501	2379907	.	+	0	Locus=ML1991;Name=PPE;Function=;Product=PPE-family protein;Comments=ML1991, len: 468 aa. Member of the PPE-family. Similar to M. tuberculosis PPE-family protein Rv0096 SW:Y096_MYCTU (Q10892) (463 aa), Fasta scores: E(): 0, 58.6% identity in 466 aa overlap. Also similar to ML1828 and ML0539 from M. leprae. Contains Pfam match to entry PF00823 PPE, PPE family.;UniProt_AC=Q9CBG5;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	2404476	2404895	.	-	0	Locus=ML2012c;Name=ML2012c;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN;Comments=ML2012c, len: 139 aa. Probable conserved membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv1903 or MTCY180.15C TR:O07729 (EMBL:Z97193) (134 aa) fasta scores: E(): 0, 80.6% identity in 129 aa and to Streptomyces coelicolor putative membrane proteins e.g. SCQ11.05C TR:Q9S1M9 (EMBL:AL096823) (125 aa) fasta scores: E(): 2.5e-15, 43.0% identity in 121 aa. Previously sequenced as TR:O33146 (EMBL:AJ000521). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=O33146;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1252907	1253297	.	+	0	Locus=ML1089A;Name=ML1089A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1089A, len:390. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-12 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2429330	2429809	.	-	0	Locus=ML2038c;Name=bfrA;Function=INVOLVED IN IRON STORAGE (MAY PERFORM ANALOGOUS FUNCTIONS IN IRON DETOXIFICATION AND STORAGE AS THAT OF ANIMAL FERRITINS); FERRITIN IS AN INTRACELLULAR MOLECULE THAT STORES IRON IN A SOLUBLE, NONTOXIC, READILY AVAILABLE FORM. THE FUNCTIONAL MOLECULE, WHICH IS COMPOSED OF 24 CHAINS, IS ROUGHLY SPHERICAL AND CONTAINS A CENTRAL CAVITY IN WHICH THE POLYMERIC FERRIC IRON CORE IS DEPOSITED.;Product=PROBABLE BACTERIOFERRITIN BFRA;Comments=ML2038c, len: 159 aa. Probable bfrA, bacterioferritin. Similar to Mycobacterium tuberculosis bacterioferritin SW:BFR_MYCTU (O08465) fasta scores: E(): 0, 90.1% in 152 aa, and to Brucella melitensis bacterioferritin SW:BFR_BRUME (P49944) fasta scores: E(): 8.5e-23, 44.6% in 139 aa. Contains Pfam match to entry PF01334 Bacteriofer, Bacterioferritin.;UniProt_AC=P43315;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2420654	2421127	.	+	0	Locus=ML2030;Name=rpfC;Function=;Product=PROBABLE RESUSCITATION-PROMOTING FACTOR RPFC;Comments=ML2030, len: 157 aa. Probable rpfC, resuscitation promoting factor. Similar to Mycobacterium tuberculosis resuscitation promoting factors: rpfC, Rv1884c TR:O07747 (EMBL:Z97193) fasta scores: E(): 0, 70.2% in 141 aa and rpfD TR:P71755 Rv2389c (EMBL:Z81368) fasta scores: E(): 2.8e-20, 47.9% in 121 aa. Also similar to ML2151 and ML0240 from M. leprae.;UniProt_AC=Q9CBF8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2435566	2436810	.	+	0	Locus=ML2046;Name=lldD2;Function=;Product=POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD2;Comments=ML2046, len: 414 aa. Possible lldD2, L-lactate dehydrogenase (EC 1.1.2.3). Similar to Mycobacterium tuberculosis LLDD2 TR:P95143 (EMBL:AQ102036) fasta scores: E(): 0, 85.0% in 413 aa, and to Escherichia coli L-lactate dehydrogenase SW:LLDD_ECOLI (P33232) fasta scores: E(): 0, 37.3% in 383 aa. Contains Pfam match to entry PF01070 FMN_dh, FMN-dependent dehydrogenase. Contains PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site.;UniProt_AC=Q9CBF2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2442189	2442488	.	-	0	Locus=ML2054c;Name=ML2054c;Function=;Product=probable integral membrane protein;Comments=ML2054c, len: 99 aa. Probable integral membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein TR:P95154 (EMBL:Z83859) fasta scores: E(): 6.4e-18, 58.4% in 101 aa, and to Escherichia coli transglycosylase associated protein SW:TAG1_ECOLI (P76011) fasta scores: E(): 0.0054, 35.1% in 77 aa.;UniProt_AC=Q9CBF0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2446563	2447237	.	+	0	Locus=ML2059;Name=ML2059;Function=;Product=POSSIBLE OXIDOREDUCTASE;Comments=ML2059, len: 224 aa. Possible oxidoreductase. Similar to Mycobacterium tuberculosis hypothetical 23.2 kda protein Rv1856c TR:P95158 (EMBL:Z83859) fasta scores: E(): 0, 80.5% in 220 aa, and to Streptomyces argillaceus ketoreductase TR:O86486 (EMBL:AJ007932) fasta scores: E(): 0.00044, 24.9% in 201 aa. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus.;UniProt_AC=O32906;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2476960	2478876	.	+	0	Locus=ML2084;Name=ML2084;Function=;Product=PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER;Comments=ML2084, len: 638 aa. Probable drugs-transport transmembrane ATP-binding protein ABC transporter. Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv1819c SW:YI19_MYCTU (Q50614) fasta scores: E(): 0, 74.9% in 634 aa, and in C-term to Escherichia coli hypothetical ABC transporter ATP-binding protein in pqql-hipa intergenic region SW:YDDA_ECOLI (P31826; P76133; P76876) fasta scores: E(): 0, 29.9% in 551 aa. Also similar to ML1089, ML1424, ML0848 and ML0590 from M. leprae. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.;UniProt_AC=O32924;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2541992	2542423	.	-	0	Locus=ML2140c;Name=ML2140c;Function=;Product=POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY MARR-FAMILY);Comments=ML2140c, len: 143 aa. Possible transcriptional regulator, MarR family. Similar to Mycobacterium tuberculosis transcriptional regulator protein Rv0880 SW:Y880_MYCTU (Q10542) fasta scores: E(): 0, 90.2% in 143 aa, and to Streptomyces coelicolor putative marR-family protein TR:CAB93410 (EMBL:AL357524) fasta scores: E(): 1.6e-13, 39.6% in 134 aa. Also similar to ML2696 and ML0550 from M. leprae. Contains Pfam match to entry PF01047 MarR, MarR family.;UniProt_AC=O33060;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2543014	2543823	.	-	0	Locus=ML2142c;Name=ML2142c;Function=;Product=conserved hypothetical protein;Comments=ML2142c, len: 269 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 27.5 kda protein Rv0877 SW:Y877_MYCTU (Q10539) fasta scores: E(): 0, 80.5% in 257 aa, and to Streptomyces coelicolor hypothetical 32.2 kda protein TR:CAB93404 (EMBL:AL357524) fasta scores: E(): 2.5e-19, 43.3% in 270 aa.;UniProt_AC=O33058;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2538742	2539872	.	+	0	Locus=ML2136;Name=serC;Function=CATALYZES THE REVERSIBLE INTERCONVERSION OF PHOSPHOSERINE AND 2-OXOGLUTARATE TO 3-PHOSPHONOOXYPYRUVATE AND GLUTAMATE. REQUIRE BOTH IN THE MAJOR PHOSPHORYLATED PATHWAY OF SERINE BIOSYNTHESIS AND IN PYRIDOXINE BIOSYNTHESIS [CATALYTIC ACTIVITY: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate].;Product=POSSIBLE PHOSPHOSERINE AMINOTRANSFERASE SERC (PSAT);Comments=ML2136, len: 376 aa. Possible serC, phosphoserine aminotransferase. Similar to Mycobacterium tuberculosis putative phosphoserine aminotransferase Rv0884c SW:SERC_MYCTU (Q10534) fasta scores: E(): 0, 87.5% in 376 aa, and to Methanosarcina barkeri phosphoserine aminotransferase SW:SERC_METBA (P52878) fasta scores: E(): 4.5e-12, 24.7% in 369 aa.;UniProt_AC=O33062;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2608120	2609055	.	-	0	Locus=ML2193c;Name=mshD;Function=;Product=ACETYLTRANSFERASE MSHD;Comments=ML2193c, len: 311 aa. Probable mshD, acetyltransferase. Similar to Mycobacterium tuberculosis acetyltransferase Rv0819 TR:O53831 (EMBL:AL022004) fasta scores: E(): 0, 75.2% in 314 aa. Contains Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family.;UniProt_AC=Q9CBC9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2613464	2614150	.	+	0	Locus=ML2200;Name=ML2200;Function=;Product=conserved hypothetical protein;Comments=ML2200, len: 228 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 23.9 kda protein Rv0813c TR:O53827 (EMBL:AL022004) fasta scores: E(): 0, 78.9% in 223 aa, and to Streptomyces coelicolor hypothetical 21.7 kda protein TR:CAB94083 (EMBL:AL358692) fasta scores: E(): 4.4e-11, 30.5% in 167 aa.;UniProt_AC=Q9CBC6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2612903	2613205	.	+	0	Locus=ML2199;Name=sseC2;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN SSEC2;Comments=ML2199, len: 100 aa. Probable sseC2, conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 10.2 kda protein Rv0814c TR:O05794 (EMBL:Z95150) fasta scores: E(): 6.5e-33, 84.0% in 100 aa, and to Saccharopolyspora erythraea hypothetical 10.2 kda protein TR:Q54084 (EMBL:M29612) fasta scores: E(): 2.7e-16, 53.0% in 100 aa.;UniProt_AC=Q9CBC7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1257028	1257735	.	+	0	Locus=ML1092A;Name=ML1092A;Function=;Product=putative malate oxidoreductase(pseudogene);Comments=ML1092A, len:704. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-74 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=conserved hypotheticals, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1256987	1257691	.	+	0	Locus=ML1092A;Name=ML1092A;Function=;Product=putative malate oxidoreductase(pseudogene);Comments=ML1092A, len:704. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-74 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=conserved hypotheticals, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2622304	2622699	.	-	0	Locus=ML2207c;Name=ML2207c;Function=;Product=conserved hypothetical protein;Comments=ML2207c, len: 131 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0807 or MTCY07H7A.02C TR:O06627 (EMBL:Z95618) (129 aa) fasta scores: E(): 0, 73.4% identity in 128 aa. Similar to Corynebacterium ammoniagenes ORF3 TR:Q9RHY2 (EMBL:AB003158) (132 aa) fasta scores: E(): 4.4e-22, 51.2% identity in 125 aa and to Streptomyces coelicolor hypothetical protein SCD25.20 TR:Q9RKK0 (EMBL:AL118514) (202 aa) fasta scores: E(): 6.6e-16, 52.5% identity in 101 aa. Previously sequenced as TR:O05761 (EMBL:Z95151).;UniProt_AC=O05761;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2625874	2626827	.	-	0	Locus=ML2210c;Name=ML2210c;Function=;Product=conserved hypothetical protein;Comments=ML2210c, len: 317 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0805 TR:O06629 (EMBL:Z95618) fasta scores: E(): 0, 82.5% id in 315 aa, and to Escherichia coli IcC protein ICC SW:ICC_ECOLI (P36650) fasta scores: E(): 1.2e-12, 30.7% identity in 215 aa.;UniProt_AC=Q50024;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2656453	2656857	.	+	0	Locus=ML2237;Name=ML2237;Function=;Product=conserved hypothetical protein (HIT family);Comments=ML2237, len: 134 aa. Conserved hypothetical protein. Similar to Mycobacterium leprae hypothetical 14.7 kda protein MLCB5.04C TR:Q9R734 (EMBL:Z95151) fasta scores: E(): 0, 100.0% identity in 134 aa, and P71816|YHI1_MYCTU|Rv0759c Conserved hypothetical protein (133 aa), fasta scores: E(): 7.4e-49, (84.848% identity in 132 aa overlap); and to Borrelia burgdorferi hypothetical 15.9 kda hit-like protein PKCI OR BB0379 SW:YHIT_BORBU (P94252) fasta scores: E(): 5.2e-11, 42.3% identity in 111 aa. Contains Pfam match to entry PF01230 HIT, HIT family. Contains PS00892 HIT family signature.;UniProt_AC=P49774;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2682867	2683157	.	-	0	Locus=ML2259c;Name=ML2259c;Function=;Product=POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2259c, len: 96 aa. Possible conserved transmembrane protein. Similar to Mycobacterium tuberculosis transmembrane protein Rv0544c OR MTCY25D10.23C TR:O06410 (EMBL:Z95558) fasta scores: E(): 3.3e-22, 64.6% identity in 96 aa. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CBB7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2686566	2687468	.	-	0	Locus=ML2263c;Name=menB;Function=;Product=PROBABLE NAPHTHOATE SYNTHASE MENB (DIHYDROXYNAPHTHOIC ACID SYNTHETASE) (DHNA SYNTHETASE);Comments=ML2263c, len: 300 aa. Probable menB, naphthoate synthase (EC 4.1.3.36). Similar to Mycobacterium tuberculosis MenB or Rv0548c or MTCY25D10.27C TR:O06414 (EMBL:Z95558) fasta scores: E(): 0, 91.9% identity in 308 aa, and to Bacillus subtilis naphthoate synthase MENB SW:MENB_BACSU (P23966) fasta scores: E(): 0, 50.4% identity in 270 aa. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.;UniProt_AC=Q9CBB5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2691804	2692808	.	+	0	Locus=ML2268;Name=menC;Function=;Product=PROBABLE MUCONATE CYCLOISOMERASE MENC (CIS,CIS-MUCONATE LACTONIZING ENZYME) (MLE);Comments=ML2268, len: 334 aa. Probable menC, muconate cycloisomerase (EC 5.5.1.1). Similar to Mycobacterium tuberculosis MenC or Rv0553 or MTCY25D10.32 TR:O06419 (EMBL:Z95558) (326 aa) fasta scores: E(): 0, 79.1% identity in 326 aa. Similar to isomerases e.g. Pseudomonas sp. chloromuconate cycloisomerase tcbD SW:TCBD_PSESQ (P27099) (370 aa) fasta scores: E(): 2.6e-10, 31.4% identity in 226 aa and to Rhodococcus opacus muconate cycloisomerase I catB SW:CATB_RHOOP (P95608) (373 aa) fasta scores: E(): 4.4e-09, 29.8% identity in 225 aa. Also similar to Amycolatopsis sp. N-acylamino acid racemase aaaR TR:Q44244 (EMBL:D30738) (368 aa) fasta scores: E(): 2.5e-06, 30.0% identity in 243 aa. Contains Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme family.;UniProt_AC=Q9CBB2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2720563	2721267	.	-	0	Locus=ML2295c;Name=ML2295c;Function=;Product=POSSIBLE PROTEASE;Comments=ML2295c, len: 234 aa. Possible protease (EC 3.4.-.-). Similar to Mycobacterium tuberculosis possible protease Rv3668c or MTV025.016C TR:O69636 (EMBL:AL022121) (232 aa) fasta scores: E(): 0, 77.1% identity in 231 aa. Shows weak similarity to the C-terminal half of some proteases e.g. Thermomonospora fusca alkaline serine protease precursor TR:O86984 (EMBL:U65895) (368 aa) fasta scores: E(): 0.0018, 31.4% identity in 153 aa.;UniProt_AC=Q9CB98;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2722984	2724189	.	-	0	Locus=ML2298c;Name=ML2298c;Function=;Product=POSSIBLE MEMBRANE-ASSOCIATED SERINE PROTEASE;Comments=ML2298c, len: 401 aa. Possible membrane-associated serine protease. Similar to Mycobacterium tuberculosis putative serine protease Rv3671c or MTV025.019C TR:O69639 (EMBL:AL022121) (397 aa) fasta scores: E(): 0, 80.9% identity in 398 aa. Similar to many putative serine proteases Streptomyces coelicolor putative serine protease SCH5.30C TR:Q9X932 (EMBL:AL035636) (385 aa) fasta scores: E(): 0, 39.0% identity in 385 aa. N-terminal half contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF00089 trypsin, Trypsin.;UniProt_AC=Q9CB95;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2725032	2725679	.	-	0	Locus=ML2300c;Name=ML2300c;Function=;Product=POSSIBLE MEMBRANE-ANCHORED THIOREDOXIN-LIKE PROTEIN (THIOL-DISULFIDE INTERCHANGE RELATED PROTEIN);Comments=ML2300c, len: 215 aa. Possible membrane protein, thioredoxin-like protein (thiol-disulfide interchange protein). Similar to Mycobacterium tuberculosis Rv3673c or MTV025.021C TR:O69641 (EMBL:AL022121) membrane protein, thioredoxin-like protein (227 aa) fasta scores: E(): 0, 71.2% identity in 215 aa. Shows weak similarity to Bacillus subtilis ResA protein resA SW:RESA_BACSU (P35160) (181 aa) fasta scores: E(): 5e-06, 31.6% identity in 114 aa and to thioredoxins. Contains hydrophobic, possible membrane-spanning region. Contains PS00194 Thioredoxin family active site.;UniProt_AC=Q9CB93;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2727669	2728457	.	-	0	Locus=ML2303c;Name=ML2303c;Function=;Product=POSSIBLE HYDROLASE;Comments=ML2303c, len: 262 aa. Possible hydrolase. Similar to Mycobacterium tuberculosis putative hydrolase Rv3677c or MTV025.025C TR:O69645 (EMBL:AL022121) (264 aa) fasta scores: E(): 0, 83.9% identity in 255 aa. Shows similarity to putative bacterial hydrolases and also to eukaryotic proteins of unknown function. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily.;UniProt_AC=Q9CB90;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2729198	2730223	.	+	0	Locus=ML2305;Name=ML2305;Function=;Product=PROBABLE ANION TRANSPORTER ATPASE;Comments=ML2305, len: 341 aa. Probable anion transporter protein (EC 3.6.1.-).  Similar to Mycobacterium tuberculosis Rv3679 SW:Y0H9_MYCTU (O69647) (340 aa) fasta scores: E(): 0, 84.2% identity in 341 aa, and to Streptomyces coelicolor putative ion-transporting ATPase TR:Q9XA36 (EMBL:AL079353) (325 aa) fasta scores: E(): 0, 52.4% identity in 330 aa.;UniProt_AC=Q9CB88;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2769449	2770201	.	+	0	Locus=ML2337;Name=ML2337;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2337, len: 250 aa. Probable conserved membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv3723  TR:O69690 (EMBL:AL022121) (254 aa) fasta scores: E(): 0, 64.4% id in 253 aa. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=O69512;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2734794	2735786	.	+	0	Locus=ML2309;Name=ML2309;Function=;Product=conserved hypothetical protein;Comments=ML2309, len: 330 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 34.4 kDa protein Rv3683 TR:O69651 (EMBL:AL022121) (319 aa) fasta scores: E(): 0, 85.8% identity in 298 aa, and to Streptomyces coelicolor conserved hypothetical protein TR:Q9X935 (EMBL:AL049731) (309 aa) fasta scores: E(): 2.2e-32, 51.5% identity in 295 aa.;UniProt_AC=Q9CB84;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2752686	2753951	.	-	0	Locus=ML2323c;Name=ask;Function=INVOLVED AT THE FIRST STEP IN THE COMMON BIOSYNTHETIC PATHWAY LEADING FROM ASP TO THE CELL WALL PRECURSOR MESO-DIAMINOPIMELATE, TO LYS, TO MET, TO ILE AND TO THR [CATALYTIC ACTIVITY: ATP + L-ASPARTATE = ADP + 4-PHOSPHO-L-ASPARTATE]. POSSIBLY ACTS IN TETRAMER CONFIGURATION, TETRAMER CONSISTING OF TWO ALPHA (CATALYTIC ACTIVITY) AND TWO BETA (FUNCTION NOT KNOWN) CHAINS.;Product=ASPARTOKINASE ASK (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA SUBUNIT (ASK-ALPHA); AND ASPARTOKINASE BETA SUBUNIT (ASK-BETA)];Comments=ML2323c, len: 421 aa. ask, aspartokinase (EC 2.7.2.4). Similar to Mycobacterium tuberculosis aspartokinase ask or Rv3709c or MTV025.057C SW:AK_MYCTU (P97048; O69676; P97181) (421 aa) fasta scores: E(): 0, 92.6% identity in 421 aa, and to Mycobacterium smegmatis aspartokinase asK SW:AK_MYCSM (P41403) (421 aa) fasta scores: E(): 0, 85.3% identity in 421 aa. Contains Pfam match to entry PF00696 aakinase, Amino acid kinase family. Contains Pfam match to entry PF01842 ACT, ACT domain. Contains PS00324 Aspartokinase signature.;UniProt_AC=Q9CB77;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2760637	2761248	.	-	0	Locus=ML2329c;Name=recR;Function=;Product=PROBABLE RECOMBINATION PROTEIN RECR;Comments=ML2329c, 203 aa. Probable recR, recombination protein. Highly similar to many recombinational DNA repair RecR orthologues e.g. Mycobacterium tuberculosis Rv3715c SW:RECR_MYCTU (O69682) (203 aa) fasta scores: E(): 0, 91.1% identity in 202 aa and Bacillus subtilis recombination protein SW:RECR_BACSU (P24277) (198 aa) fasta scores: E(): 0, 51.5% identity in 198 aa. Contains Pfam match to entry PF02132 RecR, RecR protein. Contains Pfam match to entry PF01751 Toprim, Toprim domain. Contains PS01300 RecR protein signature.;UniProt_AC=O69520;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2764455	2765717	.	+	0	Locus=ML2334;Name=ML2334;Function=;Product=POSSIBLE FATTY ACID SYNTHASE;Comments=ML2334, len: 420 aa. Possible fatty acid synthase. Similar to Mycobacterium tuberculosis fatty acid synthase Rv3720 TR:O69687 (EMBL:AL022121) (420 aa) fasta scores: E(): 0, 86.4% identity in 420 aa. The C-terminus is similar to several proteins involved in cyclopropane-fatty-acyl-phospholipid synthesis e.g. Escherichia coli SW:CFA_ECOLI (P30010) (381 aa) fasta scores: E(): 1.3e-27, 34.5% identity in 278 aa. Contains PS00107 Protein kinases ATP-binding region signature.;UniProt_AC=Q9CB74;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2792239	2793069	.	-	0	Locus=ML2350c;Name=drrC;Function=PROBABLY INVOLVED IN ACTIVE TRANSPORT OF ANTIBIOTIC AND PHTHIOCEROL DIMYCOCEROSATE (DIM) ACROSS THE MEMBRANE (EXPORT). DRRA|Rv2934|MTCY19H9.04, DRRB|Rv2937|MTCY19H9.05 AND DRRC MAY ACT JOINTLY TO CONFER DAUNORUBICIN AND DOXORUBICIN RESISTANCE BY AN EXPORT MECHANISM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE AND LOCALIZATION OF DIM INTO THE CELL WALL.;Product=PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DRRC;Comments=ML2350c, len: 276 aa. Probable drrC, daunorubicin-DIM-transport integral membrane protein ABC transporter, probably involved in daunorubicin resistance and phthiocerol dimycocerosate transport. Similar to several antibiotic resistant proteins including: Mycobacterium tuberculosis Rv2938 TR:P96207 (EMBL:Z83857) (276 aa) fasta scores: E(): 0, 79.0% identity in 276 aa and Streptomyces peucetius daunorubicin resistance transmembrane protein DrrB SW:DRRB_STRPE (P32011) (283 aa) fasta scores: E(): 2.7e-11, 23.8% identity in 252 aa. Also similar to the adjoining CDS ML2351. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CB71;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2788307	2789317	.	+	0	Locus=ML2347;Name=ML2347;Function=;Product=putative membrane protein;Comments=ML2347, len: 336 aa. Putative membrane protein. Note the low G+C content of this CDS (46%). Weakly similar in part to Q9AC02 Hypothetical protein CC0067 from Caulobacter crescentus (253 aa),  fasta scores: E(): 1.9e-11, (34.270% identity in 178 aa overlap). Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=O69510;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2789508	2790773	.	+	0	Locus=ML2348;Name=ML2348;Function=;Product=Probable glycosyltransferase;Comments=ML2348, len: 421 aa. Probable glycosyltransferase (EC 2.4.1.-). Similar to many proposed glycosyl transferases including: Mycobacterium tuberculosis hypothetical protein Rv1524 SW:YF24_MYCTU (Q50583) (414 aa) fasta scores: E(): 0, 62.6% identity in 420 aa, and to Mycobacterium avium rhamnosyltransferase RtfA TR:O69000 (EMBL:AF060183) (428 aa) fasta scores: E(): 0, 55.0% identity in 424 aa.;UniProt_AC=Q49929;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2821713	2823464	.	-	0	Locus=ML2358c;Name=fadD26;Function=;Product=FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE);Comments=ML2358c, len: 583 aa. Probable fadd26, fatty-acid-CoA synthase (EC 6.2.1.-). Similar to several e.g. Q10976|FD26_MYCTU|Rv2930 Mycobacterium tuberculosis fatty-acid-CoA ligase (583 aa), fasta scores: E(): 2e-189, (76.844% identity in 583 aa overlap); and Q7TXM1 Fatty-acid-CoA ligase FADD26from M. bovis (583 aa), fasta scores: E(): 1.1e-189, (77.015% identity in 583 aa overlap). Also similar to ML0132, ML1234, ML0138 and ML0100 from M. leprae. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme.;UniProt_AC=Q9Z5K5;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2858309	2858614	.	+	0	Locus=ML2388;Name=ML2388;Function=;Product=PROBABLE CONSERVED MEMBRANE PROTEIN;Comments=ML2388, len: 101 aa. Probable conserved membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0463 TR:O53748 (EMBL:AL021933) (97 aa) fasta scores: E(): 1.1e-18, 57.9% identity in 95 aa. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q50067;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2799411	2804879	.	-	0	Locus=ML2354c;Name=ppsD;Function=;Product=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD;Comments=ML2354c, len: 1822 aa. Probable ppsD, type-I polyketide synthase. Similar to many polyketide synthases e.g.Mycobacterium tuberculosis Rv2934 TR:P96203 (EMBL:Z83857) (1827 aa) fasta scores: E(): 0, 80.3% id in 1836 aa, and to Mycobacterium bovis mycocerosic acid synthase SW:MCAS_MYCBO (Q02251) (2110 aa) fasta scores: E(): 0, 32.7% identity in 2136 aa. Also similar to ML2353, ML2355, ML0139, ML0135, ML2354, ML2356, ML2357, ML1229 and ML0101 from M. leprae. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q9CB70;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2902479	2903591	.	-	0	Locus=ML2427c;Name=ML2427c;Function=;Product=conserved hypothetical protein;Comments=ML2427c, len: 370 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0502 SW:Y502_MYCTU (Q11167) (358 aa) fasta scores: E(): 0, 85.2% identity in 359 aa. Contains a Pfam match to PF01553 Acyltransferase. Contains Pfam match to entry PF01553 Acyltransferase, Acyltransferase.;UniProt_AC=P54878;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2794935	2799404	.	-	0	Locus=ML2353c;Name=ppsE;Function=;Product=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE;Comments=ML2353c, len: 1489 aa. Probable ppsE, type-I polyketide synthase. Similar to many polyketide synthases e.g. Mycobacterium tuberculosis Rv2935 TR:P96204 (EMBL:Z83857) (1488 aa) fasta scores: E(): 0, 82.0% id in 1493 aa. Also similar to ML2355, ML0139, ML0135, ML2354, ML2356, ML2357, ML1229 and ML0101 from M. leprae. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q49934;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2863801	2864967	.	-	0	Locus=ML2394c;Name=metB;Function=;Product=PROBABLE CYSTATHIONINE GAMMA-SYNTHASE METB (CGS) (O-SUCCINYLHOMOSERINE [THIOL]-LYASE);Comments=ML2394c, len: 388 aa. Probable metB, cystathionine [gamma]-synthase (EC4.2.99.9 ). Similar to Mycobacterium tuberculosis cystathionine gamma-synthase Rv1079 SW:METB_MYCTU (O53427) (388 aa) fasta scores: E(): 0, 87.3% identity in 387 aa, and to Corynebacterium glutamicum cystathionine gamma-synthase MetB TR:Q9RQ97 (EMBL:AF126953) (386 aa) fasta scores: E(): 0, 61.2% id in 376 aa. Contains Pfam match to entry PF01053 Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme. Contains PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site.;UniProt_AC=P46807;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2871776	2872813	.	+	0	Locus=ML2401;Name=echA9;Function=;Product=POSSIBLE ENOYL-CoA HYDRATASE ECHA9 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE);Comments=ML2401, len: 345 aa. Possible echA9, enoyl-CoA hydratase (EC 4.2.1.17).  Similar to several putative Prokaryotic and Eukaryotic enoyl-CoA hydratases including: Mycobacterium tuberculosis Rv1071c TR:O53419 (EMBL:AL021897) (345 aa) fasta scores: E(): 0, 77.7% id in 345 aa and Arabidopsis thaliana putative 3-hydroxyisobutyryl-coenzyme A hydrolase TR:O49330 (EMBL:AC002340) (410 aa) fasta scores: E(): 0, 35.1% id in 345 aa. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.;UniProt_AC=O07138;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2407307	2408605	.	-	0	Locus=ML2015c;Name=cinA;Function=;Product=PROBABLE CINA-LIKE PROTEIN CINA;Comments=ML2015c, len: 1299 bp. Probable cina, competence damage protein homolog. Similar to M. tuberculosis competence damage protein homolog cinA Rv1901 TR:O07731 (EMBL:Z97193) (430 aa), Fasta scores: E(): 0, 77.0% identity in 431 aa overlap, and to e.g. Streptococcus pneumoniae putative competence-damage protein SW:CINA_STRPN (P54184) (418 aa), Fasta scores: E(): 1.4e-22, 31.0% identity in 439 aa overlap.;UniProt_AC=Q9X7D6;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2877405	2878289	.	+	0	Locus=ML2406;Name=menA;Function=INVOLVED IN MENAQUINONE BIOSYNTHESIS. CONVERSION OF 1,4-DIHYDROXY-2-NAPHTHOATE (DHNA) TO DIMETHYLMENAQUINONE (DMK). ATTACHES OCTAPRENYLPYROPHOSPHATE, A MEMBRANE-BOUND 40-CARBON SIDE CHAIN TO DHNA. THE CONVERSION OF DHNA TO DMK PROCEEDS IN THREE STAGES: THE REMOVAL OF THE CARBOXYL GROUP OF DHNA AS CO2, THE ATTACHMENT OF THE ISOPRENOID SIDE CHAIN, AND A QUINOL-TO-QUINONE OXIDATION, WHICH IS THOUGHT TO BE SPONTANEOUS.;Product=1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE MENA (DHNA-OCTAPRENYLTRANSFERASE);Comments=ML2406, len: 294 aa. Probable menA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase (EC 2.5.1.-), integral membrane protein. Similar to Mycobacterium tuberculosis probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase Rv0534c SW:MENA_MYCTU (O06400) (292 aa) fasta scores: E(): 0, 80.6% identity in 288 aa, and to Escherichia coli 1,4-dihydroxy-2-naphthoate octaprenyltransferase menA SW:MENA_ECOLI (P32166) (308 aa) fasta scores: E(): 1.6e-24, 34.4% identity in 276 aa. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=O07134;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2064082	2065038	.	-	0	Locus=ML1711c;Name=fixB;Function=;Product=PROBABLE ELECTRON TRANSFER FLAVOPROTEIN (ALPHA-SUBUNIT) FIXB (ALPHA-ETF) (ELECTRON TRANSFER FLAVOPROTEIN LARGE SUBUNIT) (ETFLS);Comments=ML1711c, len: 318 aa. Probable fixB (alternate gene name: etfA), electron transfer flavoprotein (alpha subunit) for various dehydrogenases. Highly similar to many electron transfer flavoprotein alpha-subunits, including: Paracoccus denitrificans SW:ETFA_PARDE (P38974) (307 aa), Fasta scores: E(): 0, 43.3% identity in 307 aa overlap and Mycobacterium tuberculosis Rv3028c SW:ETFA_MYCTU (O53275) (318 aa), Fasta scores: E(): 0, 89.3% identity in 318 aa overlap. Contains Pfam match to entry PF00766 ETF_alpha, Electron transfer flavoprotein alpha subunit. Contains PS00696 Electron transfer flavoprotein alpha-subunit signature. Note previously known as eftA.;UniProt_AC=O33096;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2442648	2443511	.	-	0	Locus=ML2055c;Name=apa;Function=;Product=ALANINE AND PROLINE RICH SECRETED PROTEIN APA (FIBRONECTIN ATTACHMENT PROTEIN) (Immunogenic protein MPT32) (Antigen MPT-32) (45-kDa glycoprotein) (45/47 kDa antigen);Comments=ML2055c, len: 287 aa. Probable apa (alternate gene names: mpt32, modD), Ala-,  Pro-rich 45/47 kDa secreted protein. Previously sequenced Mycobacterium leprae TR:Q9R5V6 fasta scores: E(): 0, 100.0% in 287 aa. The product of this CDS has also been shown to be highly immunogenic, Mycobacterium leprae molybdate uptake protein SW:MODD_MYCLE (P46842) fasta scores: E(): 0, 99.3% in 287 aa, and highly similar to several proteins involved in the uptake of molybdenum in other mycobacteria e.g. Mycobacterium tuberculosis molybdate uptake secreted protein precursor Rv1860 SW:MODD_MYCTU (Q50906; O08062) fasta scores: E(): 0, 66.8% in 298 aa. Contains a possible N-terminal signal sequence. Previously known as modD.;UniProt_AC=P46842;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2340161	2341441	.	-	0	Locus=ML1953c;Name=glyA;Function=;Product=Probable Serine hydroxymethyltransferase 1 GlyA;Comments=ML1953c, len: 426 aa. Probable glyA, Serine hydroxymethyltransferase 1 (EC 2.1.2.1). Similar to M. tuberculosis serine hydroxymethyltransferase glyA1 Rv1093 SW:GLA1_MYCTU (O53441) (426 aa), Fasta scores: E(): 0, 89.9% identity in 426 aa overlap, and to many others e.g. Escherichia coli serine hydroxymethyltransferase SW:GLYA_ECOLI (P00477) (417 aa), Fasta scores: E(): 0, 53.5% identity in 415 aa overlap. Contains Pfam match to entry PF00464 SHMT, Serine hydroxymethyltransferase.;UniProt_AC=Q9X794;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2916624	2917367	.	-	0	Locus=ML2441c;Name=gpm1;Function=;Product=PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM);Comments=ML2441c, len: 247 aa. Probable gpm1, phosphoglycerate mutase. Highly similar to many phosphoglycerate mutases including: Streptomyces coelicolor  SW:PMGY_STRCO (P33158) (252 aa) fasta scores: E(): 0, 66.3% identity in 240 aa, and Mycobacterium tuberculosis phosphoglycerate mutase  Rv0489 SW:PMGY_MYCTU (Q11140) (249 aa) fasta scores: E(): 0, 89.0% identity in 236 aa. Contains Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase family.;UniProt_AC=P53531;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2491072	2492181	.	-	0	Locus=ML2095c;Name=pstS3;Function=;Product=PERIPLASMIC PHOSPHATE-BINDING LIPOPROTEIN PSTS3 (PBP-3) (PSTS3) (PHOS1);Comments=ML2095c, len: 369 aa. Probable pstS3 (previously known as phoS2), phosphate-binding lipoprotein component of inorganic phosphate transport system.  Similar to Mycobacterium tuberculosis phosphate-binding protein 3 precursor TR:O86343 Rv0928 (EMBL:Z95209) fasta scores: E(): 0, 77.3% in 370 aa, and to Escherichia coli phosphate-binding periplasmic protein precursor SW:PSTS_ECOLI (P06128; P76744) fasta scores: E(): 4.4e-22, 31.2% in 333 aa. Also similar to ML2192c from M. leprae. Contains Pfam match to entry PF01449 PstS, Phosphate-binding protein. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Previously known as phoS2.;UniProt_AC=Q9CBE5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2969708	2970874	.	-	0	Locus=ML2494c;Name=dnaJ1;Function=;Product=PROBABLE CHAPERONE PROTEIN DNAJ1;Comments=ML2494c, len: 388 aa. Probable dnaJ1, chaperone protein. Similar to Mycobacterium tuberculosis DnaJ protein Rv0352 SW:DNAJ_MYCTU (P07881; O08380) fasta scores: E(): 0, 91.8% identity in 391 aa. Also similar to ML0625 from M. leprae. Contains Pfam match to entry PF01556 DnaJ_C, DnaJ C terminal region. Contains Pfam match to entry PF00684 DnaJ_CXXCXGXG, DnaJ central domain (4 repeats). Contains Pfam match to entry PF00226 DnaJ, DnaJ domain. Contains PS00636 Nt-dnaJ domain signature. Contains PS00637 CXXCXGXG dnaJ domain signature. Note previously known as dnaJ.;UniProt_AC=Q02605;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2642867	2645041	.	-	0	Locus=ML2226c;Name=ptrB;Function=;Product=PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B);Comments=ML2226c, len: 724 aa. Probable ptrB, protease II (EC 3.4.21.83). Similar at the C-terminal region to Mycobacterium tuberculosis hypothetical ptrBb Rv0782 OR MTCY369.26 TR:P71835 (EMBL:Z80226) fasta scores: E(): 0, 77.8% identity in 519 aa, and at the N-terminal region to Rv0781|ptrBa (236 aa), fasta scores: E(): 4.1e-62, (69.912% identity in 226 aa overlap). Also similar to Escherichia coli protease ii PTRB OR TLP SW:PTRB_ECOLI (P24555; P78068) fasta scores: E(): 0, 38.2% identity in 702 aa. Contains Pfam match to entry PF00326 Peptidase_S9, Prolyl oligopeptidase family.;UniProt_AC=O05748;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1920920	1922326	.	-	0	Locus=ML1596c;Name=amiC;Function=;Product=PROBABLE AMIDASE AMIC (AMINOHYDROLASE);Comments=ML1596c, len: 468 aa. Probable amiC, amidase (EC 3.5.1.4). Highly similar to several proposed amidases including: Pseudomonas putida SW:AMID_PSEPU (O69768) (466 aa), Fasta scores: E(): 2.9e-19, 29.0% identity in 469 aa overlap and Mycobacterium tuberculosis Rv2888c SW:AMI3_MYCTU (Q10811) (473 aa), Fasta scores: E(): 0, 76.7% identity in 468 aa overlap. Contains Pfam match to entry PF01425 Amidase, Amidase. Contains PS00571 Amidases signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O33040;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1913904	1914842	.	-	0	Locus=ML1589c;Name=cdsA;Function=;Product=PROBABLE INTEGRAL MEMBRANE PHOSPHATIDATE CYTIDYLYLTRANSFERASE CDSA (CDP-DIGLYCERIDE SYNTHETASE) (CDP-DIGLYCERIDE PYROPHOSPHORYLASE) (CDP-DIACYLGLYCEROL SYNTHASE) (CDS) (CTP:PHOSPHATIDATE CYTIDYLYLTRANSFERASE) (CDP-DAG SYNTHASE) (CDP-DG SYNTHETASE);Comments=ML1589c, len: 312 aa. Probable cdsA, integral membrane phosphatidate cytidylyltransferase (EC 2.7.7.41). Highly similar to several e.g. Mycobacterium tuberculosis Rv2881c SW:CDSA_MYCTU (Q10807) (306 aa), Fasta scores: E(): 0, 70.3% identity in 313 aa overlap and Q8FP76 Putative phosphatidate cytidylyltrans from Corynebacterium efficiens (297 aa), fasta score: E(): 6.2e-54, (48.986% identity in 296 aa overlap). Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01148 Cytidylyltrans, Phosphatidate cytidylyltransferase. Contains PS01315 Phosphatidate cytidylyltransferase signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CBU1;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2624331	2625959	.	+	0	Locus=ML2209;Name=cpsY;Function=;Product=POSSIBLE UDP-GLUCOSE-4-EPIMERASE CPSY (GALACTOWALDENASE) (UDP-GALACTOSE-4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE-4-EPIMERASE) (URIDINE DIPHOSPHO-GALACTOSE-4-EPIMERASE);Comments=ML2209, len: 542 aa. Probable cpsY, UDP-glucose-4-epimerase (EC 5.1.3.2). Similar to Mycobacterium tuberculosis hypothetical 60.3 kda protein Rv0806c TR:O06628 (EMBL:Z95618) fasta scores: E(): 0, 82.3% id in 530 aa, and to Neisseria meningitidis capsule gene complex upd-glucose-4-epimerase TR:Q51151 (EMBL:L09188) fasta scores: E(): 9.2e-26, 30.0% identity in 317 aa.;UniProt_AC=Q50025;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2765714	2767549	.	-	0	Locus=ML2335c;Name=dnaZX;Function=DNA POLYMERASE III IS A COMPLEX, MULTICHAIN ENZYME  RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THIS DNA POLYMERASE ALSO EXHIBITS 3' TO 5' EXONUCLEASE ACTIVITY [CATALYTIC ACTIVITY: N DEOXYNUCLEOSIDE TRIPHOSPHATE = N PYROPHOSPHATE + DNA(N)].;Product=DNA POLYMERASE III (SUBUNIT GAMMA/TAU) DNAZ/X;Comments=ML2335c, len: 611 aa. dnaZX, DNA polymerase III, subunit gamma/tau (EC 2.7.7.7). Highly similar to many DNA polymerase III subunit gamma/tau including: Mycobacterium tuberculosis DnaZX Rv3721c SW:DP3X_MYCTU (O69688) (578 aa) fasta scores: E(): 0, 78.7% identity in 602 aa and to Escherichia coli SW:DP3X_ECOLI (P06710; Q47721) (643 aa) fasta scores: E(): 0, 34.2% identity in 521 aa. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O69514;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2021826	2022980	.	-	0	Locus=ML1678c;Name=ddlA;Function=;Product=PROBABLE D-ALANINE--D-ALANINE LIGASE DDLA (D-ALANYLALANINE SYNTHETASE) (D-ALA-D-ALA LIGASE);Comments=ML1678c, len: 384 aa. Probable ddlA, D-alanine-D-alanine ligase A (EC 6.3.2.4). Highly similar to D-alanine--D-alanine ligase A from many including: Salmonella typhimurium SW:DDLA_SALTY (P15051) (363 aa), Fasta scores: E(): 0, 43.5% identity in 368 aa overlap and Mycobacterium tuberculosis Rv2981c SW:DDL_MYCTU (P95114) (373 aa), Fasta scores: E(): 0, 81.7% identity in 367 aa overlap. Contains Pfam match to entry PF01820 Dala_Dala_ligas, D-ala D-ala ligase. Contains PS00844 D-alanine--D-alanine ligase signature 2. Contains PS00843 D-alanine--D-alanine ligase signature 1.;UniProt_AC=Q9CBS0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2339277	2340104	.	-	0	Locus=ML1952c;Name=desA2;Function=THOUGHT TO CATALYZE THE PRINCIPAL CONVERSION OF SATURATED FATTY ACIDS TO UNSATURATED FATTY ACIDS. THOUGHT TO CONVERT STEAROYL-ACP TO OLEOYL-ACP BY INTRODUCTION OF A CIS DOUBLE BOND BETWEEN CARBONS DELTA-9 AND DELTA-10 OF THE ACYL CHAIN [CATALYTIC ACTIVITY: Stearoyl-[acyl-carrier protein] + AH2 + O2 = oleoyl-[acyl-carrier protein] + A + 2 H2O].;Product=POSSIBLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA2 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE);Comments=ML1952c, len: 275 aa. Possible desA2, acyl-[acyl-carrier protein] desaturase (stearoyl-ACP desaturase) (EC 1.14.99.6). Similar to M. tuberculosis acyl-[ACP] desaturase desA2 TR:O53442 (EMBL:AL021897) (275 aa), Fasta scores: E(): 0, 78.1% identity in 274 aa overlap, and to others e.g. Gossypium hirsutum (Upland cotton) acyl-[acyl-carrier protein] desaturase precursor SW:STAD_GOSHI (X95988) (397 aa), Fasta scores: E(): 5.6e-05, 23.9% identity in 293 aa overlap. Also similar to ML2185 from M. leprae.;UniProt_AC=Q9X793;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2023092	2024147	.	-	0	Locus=ML1679c;Name=gpdA2;Function=;Product=PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(P)+] GPDA (NAD(P)H- DEPENDENT GLYCEROL-3-PHOSPHATE DEHYDROGENASE);Comments=ML1679c, len: 351 aa. Probable gpdA, glycerol-3-phosphate dehydrogenase (EC 1.1.1.94). Highly similar to many glycerol-3-phosphate dehydrogenases including: Escherichia coli SW:GPDA_ECOLI (P37606) (339 aa), Fasta scores: E(): 0, 39.9% identity in 341 aa overlap and Mycobacterium tuberculosis Rv2982c TR:P95113 (EMBL:Z83018) (334 aa), Fasta scores: E(): 0, 77.9% identity in 349 aa overlap. Contains Pfam match to entry PF01210 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase.;UniProt_AC=Q9CBR9;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1258677	1258826	.	-	0	Locus=ML1093A;Name=ML1093A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1093A, len:149. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.001 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2793066	2793932	.	-	0	Locus=ML2351c;Name=drrB;Function=PROBABLY INVOLVED IN ACTIVE TRANSPORT OF ANTIBIOTIC AND PHTHIOCEROL DIMYCOCEROSATE (DIM) ACROSS THE MEMBRANE (EXPORT). DRRA|Rv2934|MTCY19H9.04, DRRB AND DRRC|Rv2938|MTCY19H9.06 MAY ACT JOINTLY TO CONFER DAUNORUBICIN AND DOXORUBICIN RESISTANCE BY AN EXPORT MECHANISM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE AND LOCALIZATION OF DIM INTO THE CELL WALL.;Product=PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DRRB;Comments=ML2351c, len: 288 aa. Probable drrB, daunorubicin-DIM-transport integral membrane protein ABC transporter, probably involved in daunorubicin resistance and phthiocerol dimycocerosate transport. Similar to several antibiotic resistant proteins including: Mycobacterium tuberculosis Rv2937 TR:P96206 (EMBL:Z83857) (289 aa) fasta scores: E(): 0, 64.0% identity in 289 aa and Streptomyces peucetius daunorubicin resistance transmembrane protein DrrB SW:DRRB_STRPE (P32011) (283 aa) fasta scores: E(): 4.2e-06, 22.7% identity in 229 aa. Also similar to the adjoining CDS ML2350. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q49935;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2268194	2268952	.	-	0	Locus=ML1889c;Name=end;Function=INVOLVED IN BASE EXCISION REPAIR. ENDONUCLEASE IV PLAYS A ROLE IN DNA REPAIR. IT CLEAVES PHOSPHODIESTER BONDS AT APURINIC OR APYRIMIDINIC SITES (AP SITES) TO PRODUCE NEW 5' ENDS THAT ARE BASE-FREE DEOXYRIBOSE 5-PHOSPHATE RESIDUES [CATALYTIC ACTIVITY: Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products].;Product=PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE);Comments=ML1889c, len: 252 aa. Probable end, endonuclease IV (EC 3.1.21.2). Similar to Mycobacterium tuberculosis probable endonuclease IV nfo or end or Rv0670 or MTCI376.04C SW:END4_MYCTU (O86366) (252 aa) fasta scores: E(): 0, 85.6% identity in 250 aa. Similar to many putative endonucleases. Previously sequenced as SW:END4_MYCLE (P30770). Contains Pfam match to entry PF01261 AP_endonulease2, AP endonuclease family 2. Contains PS00730 AP endonucleases family 2 signature 2. Contains PS00731 AP endonucleases family 2 signature 3. Contains PS00729 AP endonucleases family 2 signature 1.;UniProt_AC=P30770;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2187641	2188402	.	-	0	Locus=ML1807c;Name=fabG1;Function=;Product=3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEIN) ;Comments=ML1807c, len: 253 aa. Probable fabG1, 3-oxoacyl-[ACP] reductase (EC 1.1.1.100). Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa), Fasta scores: E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa), Fasta scores: E(): 0, 47.3% identity in 241 aa overlap. Also similar to ML1806, ML2565, ML1740, ML1094, ML0862, ML0135, ML0135, ML0429, ML2357, ML0108 and ML2059 from M. leprae. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature.;UniProt_AC=Q9CBM0;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2571317	2572528	.	-	0	Locus=ML2162c;Name=fadA;Function=;Product=POSSIBLE ACYL-CoA THIOLASE FADA;Comments=ML2162c, len: 403 aa. Possible fadA, acyl-CoA thiolase (EC 2.3.1.-). Similar to Mycobacterium tuberculosis putative acyl- CoA thiolase Rv0859 TR:O53871 (EMBL:AL022004) fasta scores: E(): 0, 94.5% in 403 aa, and to Escherichia coli acetyl-coa acetyltransferase TR:O53017 (EMBL:X97452) fasta scores: E(): 0, 44.1% in 422 aa, and to Acinetobacter calcoaceticus beta-ketoadipyl coa thiolase SW:PCAF_ACICA (Q43974) fasta scores: E(): 0, 40.9% in 425 aa. Also similar to ML1158 and ML2564 from M. leprae. Contains Pfam match to entry PF00108 thiolase, Thiolase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00098 Thiolases acyl-enzyme intermediate signature. Contains PS00099 Thiolases active site. Contains PS00737 Thiolases signature 2.;UniProt_AC=Q9CBD7;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2452186	2453637	.	+	0	Locus=ML2065;Name=gnd1;Function=;Product=PROBABLE 6-PHOSPHOGLUCONATE DEHYDROGENASE GND1;Comments=ML2065, len: 483 aa. Probable gnd1, 6-phosphogluconate dehydrogenase (EC 1.1.1.44). Similar to Mycobacterium tuberculosis cosmid gnd TR:P95165 (EMBL:AL008609) fasta scores: E(): 0, 86.8% in 485 aa and to Bacillus subtilis 6-phosphogluconate dehydrogenase, decarboxylating II SW:6PG2_BACSU (P80859; P54546) fasta scores: E(): 0, 55.7% in 465 aa. Contains Pfam match to entry PF00393 6PGD, 6-phosphogluconate dehydrogenases.;UniProt_AC=Q9CBE9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2535820	2537487	.	-	0	Locus=ML2134c;Name=fprB;Function=;Product=PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE);Comments=ML2134c, len: 555 aa. Probable fprB, ferredoxin, ferredoxin-NADP reductase (EC 1.18.1.2). Similar to Mycobacterium tuberculosis probable ferredoxin/ferredoxin--NADP reductase Rv0886 SW:FPRB_MYCTU (Q10547) fasta scores: E(): 0, 76.6% in 560 aa, and to Homo sapiens NADPH:adrenodoxin oxidoreductase precursor SW:ADRO_HUMAN (P22570; Q13716) fasta scores: E(): 2.9e-30, 37.4% in 484 aa. Contains 2 Pfam matches to entry PF00037 fer4, 4Fe-4S binding domain. Contains PS00198 4Fe-4S ferredoxins.;UniProt_AC=O33064;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2333631	2335055	.	+	0	Locus=ML1947;Name=fum;Function=;Product=PROBABLE FUMARASE FUM (Fumarate hydratase);Comments=ML1947, len: 474 aa. Probable fum, fumarase (EC 4.2.1.2). Similar to M. tuberculosis fumarase Rv1098c fum TR:O53446 (EMBL:AL021897) (474 aa), Fasta scores: E(): 0, 89.5% identity in 467 aa overlap, and to many others e.g Homo sapiens fumarate hydratase, mitochondrial precursor SW:FUMH_HUMAN (P07954) (510 aa), Fasta scores: E(): 0, 52.1% identity in 461 aa overlap. Also similar to ML1413 and ML2230 from M. leprae. Contains Pfam match to entry PF00206 lyase_1, Lyase. Contains PS00163 Fumarate lyases signature.;UniProt_AC=Q9X789;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1959892	1962906	.	-	0	Locus=ML1630c;Name=glnE;Function=REGULATORY PROTEIN INVOLVED IN THE REGULATION OF GLUTAMINE SYNTHETASE ACTIVITY. ADENYLYLATION AND DEADENYLYLATION OF GLUTAMINE SYNTHETASE. POSSIBLY REGULATES GLNB|Rv2919c [CATALYTIC ACTIVITY: ATP + [L-GLUTAMATE:AMMONIA LIGASE (ADP-FORMING)] = PYROPHOSPHATE + ADENYLYL-[L-GLUTAMATE:AMMONIA LIGASE (ADP-FORMING)]].;Product=GLUTAMATE-AMMONIA-LIGASE ADENYLYLTRANSFERASE GLNE (Glutamine-synthetase adenylyltransferase);Comments=ML1630c, len: 1004 aa. Probable glnE, glutamate-ammonia-ligase adenyltransferase (EC 2.7.7.42). Similar to several glutamate-ammonia-ligase adenylyltransferases including: Escherichia coli SW:GLNE_ECOLI (P30870) (946 aa), Fasta scores: E(): 2.4e-21, 28.2% identity in 929 aa overlap and Mycobacterium tuberculosis Rv2221c SW:GLNE_MYCTU (Q10379) (994 aa), Fasta scores: E(): 0, 82.8% identity in 998 aa overlap.;UniProt_AC=Q9CBT4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2033591	2035099	.	-	0	Locus=ML1688c;Name=gltS;Function=;Product=PROBABLE GLUTAMYL-TRNA SYNTHETASE GLTS (GLUTAMATE--TRNA LIGASE) (GLUTAMYL-TRNA SYNTHASE) (GLURS);Comments=ML1688c, len: 502 aa. Probable gltS, glutamyl-tRNA synthase (EC 6.1.1.17). Highly similar to many glutamyl-tRNA synthetases including: Bacillus subtilis SW:SYE_BACSU (P22250) (483 aa), Fasta scores: E(): 0, 37.4% identity in 486 aa overlap and Mycobacterium tuberculosis Rv2992c SW:SYE_MYCTU (O53241) (490 aa), Fasta scores: E(): 0, 81.4% identity in 488 aa overlap. Contains Pfam match to entry PF00749 tRNA-synt_1c, tRNA synthetases class I (E and Q).;UniProt_AC=O33120;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2907143	2907985	.	-	0	Locus=ML2432c;Name=ML2432c;Function=;Product=conserved hypothetical protein;Comments=ML2432c, len: 280 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0498 SW:Y498_MYCTU (Q11163) (280 aa) fasta scores: E(): 0, 89.3% identity in 280 aa, and to Streptomyces coelicolor hypothetical protein TR:Q9X8H0 (EMBL:AL049819) (285 aa) fasta scores: E(): 3.2e-30, 51.6% identity in 273 aa.;UniProt_AC=P54581;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2701274	2702137	.	+	0	Locus=ML2278;Name=htpX;Function=;Product=PROBABLE PROTEASE TRANSMEMBRANE PROTEIN HEAT SHOCK PROTEIN HTPX;Comments=ML2278, len: 287 aa. Probable htpX, protease heat shock protein X (EC 3.4.24.-) (transmembrane protein). Similar to Mycobacterium tuberculosis probable protease htpX or Rv0563 or MTV039.01 or MTCY25D10.42 SW:HTPX_MYCTU (O06429) (286 aa) fasta scores: E(): 0, 88.5% identity in 286 aa. Similar to many homologues of Escherichia coli probable protease and heat-shock protein HtpX SW:HTPX_ECOLI (P23894) (293 aa) blastp scores: 78.1 bits, 30% identity in 253 aa. Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF01435 Peptidase_M48, Peptidase family M48. Contains PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.;UniProt_AC=Q9CBA4;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2475220	2476866	.	-	0	Locus=ML2083c;Name=ilvG;Function=;Product=Probable Acetolactate synthase IlvG (Acetohydroxy-acid synthase)(ALS);Comments=ML2083c, len: 548 aa. Probable ilvG, Acetolactate synthase (EC 4.1.3.18). Similar to Mycobacterium tuberculosis probable acetolactate synthase SW:ILVG_MYCTU (Q50613) fasta scores: E(): 0, 86.1% in 548 aa, and to Bacillus subtilis acetolactate synthase large subunit SW:ILVB_BACSU (P37251; P94564) fasta scores: E(): 1.2e-32, 28.5% in 543 aa. Also similar to ML1696, ML2167 and ML0354 from M. leprae. Contains Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzymes. Contains PS00187 Thiamine pyrophosphate enzymes signature.;UniProt_AC=O32923;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2030179	2031636	.	-	0	Locus=ML1685c;Name=leuC;Function=;Product=PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (LARGE SUBUNIT) LEUC (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI);Comments=ML1685c, len: 485 aa. Probable leuC, 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33). Highly similar to many 3-isopropylmalate dehydratase large subunits involved in leucine biosynthesis, including: Escherichia coli SW:LEU2_ECOLI (P30127) (465 aa), Fasta scores: E(): 0, 61.3% identity in 463 aa overlap and Mycobacterium tuberculosis Rv2988c SW:LEU2_MYCTU (O53237) (473 aa), Fasta scores: E(): 0, 88.7% identity in 471 aa overlap. Contains Pfam match to entry PF00330 aconitase, Aconitase family (aconitate hydratase). Contains PS01244 Aconitase family signature 2. Contains PS00450 Aconitase family signature 1.;UniProt_AC=O33123;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2219409	2220209	.	-	0	Locus=ML1831c;Name=mapA;Function=;Product=PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP);Comments=ML1831c, len: 266 aa. Probable mapA, methionine aminopeptidase (EC 3.4.11.18). Similar to M. tuberculosis methionine aminopeptidase mapA Rv0734 TR:O53797 (EMBL:AL021958) (266 aa), Fasta scores: E(): 0, 84.0% identity in 262 aa overlap, and to many others e.g. Bacillus subtilis methionine aminopeptidase SW:AMPM_BACSU (P19994) (248 aa), Fasta scores: E(): 0, 43.3% identity in 245 aa overlap. Also similar to ML1576 and ML0521 from M. leprae. Contains Pfam match to entry PF00557 Peptidase_M24, metallopeptidase family M24.;UniProt_AC=O33008;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2905097	2905357	.	-	0	Locus=ML2429c;Name=ML2429c;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML2429c, len: 86 aa. Conserved hypothetical protein. Similar to several including: Rv0500A  conserved hypothetical protein from M. tuberculosis (78 aa), fasta scores: E(): 9.7e-27, (82.558% identity in 86 aa overlap) and Streptomyces coelicolor hypothetical protein TR:Q9WX06 (EMBL:AL079345) (70 aa) fasta scores: E(): 3.4e-14, 68.3% identity in 63 aa. Contains a probable helix-turn-helix motif at aa 33-54 (Score 1515, SD +4.35). Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q49828;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2861609	2862481	.	-	0	Locus=ML2391c;Name=mca;Function=;Product=Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase);Comments=ML2391c, len: 290 aa. Probable mca, mycothiol conjugate amidase. Similar to Mycobacterium tuberculosis mca, mycothiol conjugate amidase Rv1082 TR:O53430 (EMBL:AL021897) (288 aa) fasta scores: E(): 0, 86.4% identity in 287 aa. Also weakly similar to Streptomyces lincolnensis lmbE TR:Q54358 (EMBL:X79146) (270 aa) fasta scores: E(): 8.9e-13, 33.0% identity in 282 aa. Also similar to ML1495 from M. leprae.;UniProt_AC=Q50060;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2681384	2682490	.	-	0	Locus=ML2257c;Name=menE;Function=;Product=POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE);Comments=ML2257c, len: 368 aa. Possible menE, o-succinylbenzoic acid-CoA ligase (EC 6.2.1.26). Similar to Mycobacterium tuberculosis MenE or Rv0542c or MTCY25D10.21C TR:O06408 (EMBL:Z95558) fasta scores: E(): 0, 78.3% identity in 359 aa, and to Escherichia coli o-succinylbenzoic acid--coa ligase MENE SW:MENE_ECOLI (P37353; P78253; P78178) fasta scores: E(): 7e-18, 30.0% identity in 377 aa. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature.;UniProt_AC=Q9CBB8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2932070	2932957	.	+	0	Locus=ML2459;Name=pcaA;Function=;Product=MYCOLIC ACID SYNTHASE PCAA (CYCLOPROPANE SYNTHASE);Comments=ML2459, len: 295 aa. Probable pcaA, Mycolic acid synthase. Highly similar to many mycobacterial mycolic acid synthases including:  pcaA|Rv0470c Mycobacterium tuberculosis pcaA, Mycolic acid synthase Rv3392c SW:CFA1_MYCTU (Q11195) (287 aa), fasta scores: E(): 0, 69.0% identity in 287 aa and to Mycobacterium bovis Q7U1X4 Mycolic acid synthase PCAA (287 aa), fasta scores: E(): 5.9e-112, (81.882% identity in 287 aa overlap). Also similar to ML1900 and ML1903 from M. leprae.;UniProt_AC=Q9CB40;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2099988	2100926	.	-	0	Locus=ML1740c;Name=ML1740c;Function=;Product=PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE;Comments=ML1740c, len: 312 aa. Probable oxidoreductase, probably short-chain alcohol dehydrogenase/reductase (EC 1.1.-.-). Similar to several including: Thermotoga maritima 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_THEMA (Q9X248) (246 aa), Fasta scores: E(): 1.4e-18, 33.2% identity in 193 aa overlap and Mycobacterium tuberculosis possible ketoacyl reductase Rv3057c TR:P95101 (EMBL:Z83866) (287 aa), Fasta scores: E(): 0, 81.8% identity in 280 aa overlap. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature.;UniProt_AC=Q9CBP7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2948774	2949289	.	+	0	Locus=ML2474;Name=ML2474;Function=;Product=possible cytidine/deoxycytidylate deaminase;Comments=ML2474, len: 171 aa. Possible cytidine/deoxycytidylate deaminase (EC 3.5.4.-). Similar to several including: Mycobacterium tuberculosis probable cytidine/deoxycytidylate deaminase Rv3752c TR:O69719 (EMBL:AL022121) fasta scores: E(): 0, 87.4% identity in 151 aa, and to Neisseria meningitidis putative cytosine deaminase TR:CAB84390 (EMBL:AL162755) fasta scores: E(): 2e-19, 42.9% identity in 147 aa. Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region. Contains PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.;UniProt_AC=Q9CB32;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2121326	2122234	.	-	0	Locus=ML1752c;Name=ML1752c;Function=;Product=conserved hypothetical protein;Comments=ML1752c, len: 302 aa. Conserved hypothetical protein. Similar to many including the C-terminus of several putative phosphodiesterases e.g. Streptomyces coelicolor TR:Q9Z584 (EMBL:AL035569) (746 aa), Fasta scores: E(): 2.5e-32, 38.4% identity in 305 aa overlap as well as several proteins of undefined function e.g. Mycobacterium tuberculosis Rv1357c SW:YD57_MYCTU (Q11027) (307 aa), Fasta scores: E(): 0, 73.9% identity in 261 aa overlap. Also similar to the C-terminus of ML1750 from M. leprae. Contains Pfam match to entry PF00563 DUF2, Domain of unknown function 2.;UniProt_AC=Q9CBP4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2176926	2177909	.	-	0	Locus=ML1798c;Name=ML1798c;Function=;Product=Possible transport system kinase;Comments=ML1798c, len: 327 aa. Possible transport system kinase. Similar to M. tuberculosis Rv1496 SW:YE96_MYCTU (P71777) (334 aa), Fasta scores: E(): 0, 83.0% identity in 323 aa overlap and to other members of the argK family e.g. SW:ARGK_ECOLI (P27254) (331 aa), Fasta scores: E(): 0, 44.9% identity in 321 aa overlap LAO/AO transport system kinase. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CBM8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2198962	2200599	.	-	0	Locus=ML1816c;Name=ML1816c;Function=;Product=PROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER;Comments=ML1816c, len: 545 aa. Possible macrolide-transport ATP-binding protein ABC transporter.  Similar to M. tuberculosis Rv1473 TR:O53164 (EMBL:AL021184) (542 aa), Fasta scores: E(): 0, 87.9% identity in 545 aa overlap, and to many others e.g. Haemophilus influenzae hypothetical ABC transporter ATP-binding protein SW:YHES_HAEIN (P44808) (638 aa), Fasta scores: E(): 1.4e-30, 31.5% identity in 518 aa overlap. Also similar to ML1248, ML0669, ML0848, ML2189, ML1122, ML0114 and ML0336 from M. leprae. Contains 2 Pfam matches to entry PF00005 ABC_tran, ABC transporter. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop). Contains 2 x PS00211 ABC transporters family signature.;UniProt_AC=Q9CBL2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2533165	2533785	.	-	0	Locus=ML2131c;Name=pdxH;Function=;Product=PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE PDXH (PNP/PMP OXIDASE) (PYRIDOXINEPHOSPHATE OXIDASE) (PNPOX) (PYRIDOXINE 5'-PHOSPHATE OXIDASE);Comments=ML2131c, len: 206 aa. Probable pdxH, pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5). Similar to Mycobacterium tuberculosis pyridoxamine 5'-phosphate oxidase Rv2607 SW:PDXH_MYCTU (O06207) fasta scores: E(): 0, 69.3% in 205 aa, and to Escherichia coli pyridoxamine 5'-phosphate oxidase SW:PDXH_ECOLI (P28225) fasta scores: E(): 9.8e-27, 43.3% in 171 aa. Contains Pfam match to entry PF01243 Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase. Contains PS01064 Pyridoxamine 5'-phosphate oxidase signature.;UniProt_AC=O33065;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2543933	2545672	.	+	0	Locus=ML2143;Name=ML2143;Function=;Product=POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2143, len: 579 aa. Possible conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 57.9 kda protein Rv0876c SW:Y876_MYCTU (Q10564) fasta scores: E(): 0, 81.2% in 568 aa, and to Streptomyces coelicolor putative integral membrane protein TR:CAB93403 (EMBL:AL357524) fasta scores: E(): 5.3e-16, 38.8% in 448 aa. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=O33057;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2726917	2727591	.	+	0	Locus=ML2302;Name=ML2302;Function=;Product=PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY CRP/FNR-FAMILY);Comments=ML2302, len: 224 aa. Probable transcriptional regulatory protein (Crp/Fnr family). Similar to Mycobacterium tuberculosis putative transcriptional regulator Rv3676 or MTV025.024 TR:O69644 (EMBL:AL022121) (224 aa) fasta scores: E(): 0, 96.0% identity in 224 aa. Similar to many e.g. Haemophilus influenzae catabolite gene activator crp or cap or HI0957 SW:CRP_HAEIN (P29281) (224 aa) fasta scores: E(): 2.4e-14, 32.6% identity in 187 aa. Also similar to ML2345 a possible pseudogene similar to M. tuberculosis Rv3676. Contains a probable helix-turn-helix motif at aa 175-196 (Score 1990, SD +5.96) Contains Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family. Contains Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain.;UniProt_AC=Q9CB91;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2728463	2728918	.	-	0	Locus=ML2304c;Name=ML2304c;Function=;Product=conserved hypothetical protein;Comments=ML2304c, len: 151 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv3678c or MTV025.026C TR:O69646 (EMBL:AL022121) (151 aa) fasta scores: E(): 0, 78.1% identity in 151 aa. Similar to Streptomyces coelicolor hypothetical protein SCH17.09C TR:Q9XA38 (EMBL:AL079353) (155 aa) fasta scores: E(): 1.7e-31, 64.7% identity in 150 aa. Also similar to eukaryotic proteins Trypanosoma cruzi Pb5 pb5 TR:O96876 (EMBL:U67906) (160 aa) fasta scores: E(): 3.4e-20, 50.7% identity in 150 aa and to Leishmania major hypothetical protein l7276.02 TR:Q9U0W7 (EMBL:AL133436) (163 aa) fasta scores: E(): 1.6e-16, 46.1% identity in 152 aa. Contains Pfam match to entry PF01042 UPF0076, Domain of unknown function. Contains PS00044 Bacterial regulatory proteins, lysR family signature. Note start changed since original submission.;UniProt_AC=Q9CB89;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2494509	2495789	.	+	0	Locus=ML2098;Name=mntH;Function=;Product=DIVALENT CATION-TRANSPORT INTEGRAL MEMBRANE PROTEIN MNTH (BRAMP) (MRAMP);Comments=ML2098, len: 426 aa. Probable mntH (alternative gene name: Nramp, Mramp),  H+-dependent divalent cation-transport integral membrane protein. Similar to Mycobacterium tuberculosis mntH, H+-dependent divalent cation-transport integral membrane protein SW:MNTH_MYCTU (O05916) (428 aa),  fasta scores: E(): 0, 74.8% in 413 aa, and to Bacillus subtilis probable manganese transport protein mntH SW:MNTH_BACSU (P96593) fasta scores: E(): 0, 44.1% in 415 aa, and to Salmonella typhimurium manganese transport protein mnth SW:MNTH_SALTY (Q9RPF4) fasta scores: E(): 0, 43.1% in 406 aa. Contains Pfam match to entry PF01566 Nramp, Natural resistance-associated macrophage protein.;UniProt_AC=Q50103;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2190485	2191618	.	-	0	Locus=ML1810c;Name=moxR1;Function=;Product=PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN MOXR1;Comments=ML1810c, len: 377 aa. Probable moxR1, transcriptional regulatory protei. Similar to M. tuberculosis moxR Rv1479 TR:O53170 (EMBL:AL021184) (377 aa), Fasta scores: E(): 0, 90.2% identity in 377 aa overlap, to many other moxR homologs and to e.g. Pyrococcus abyssi MOXR-3 TR:Q9UZ67 (EMBL:AJ248287) (314 aa), Fasta scores: E(): 0, 46.6% identity in 313 aa overlap. Contains Pfam match to entry PF01078 Mg_chelatase, Magnesium chelatase, subunit ChlI.;UniProt_AC=Q9CBL7;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2575972	2577681	.	+	0	Locus=ML2167;Name=pdc;Function=;Product=PROBABLE PYRUVATE OR INDOLE-3-PYRUVATE DECARBOXYLASE PDC;Comments=ML2167, len: 569 aa. Probable pdc, pyruvate or indole-pyruvate decarboxylase (EC 4.1.1.-). Highly similar to Mycobacterium tuberculosis Rv0853c putative pyruvate/indole-pyruvate carboxylase TR:O53865 (EMBL:AL022004) fasta scores: E(): 0, 79.2% in 543 aa, and to Enterobacter cloacae indole-3-pyruvate decarboxylase SW:DCIP_ENTCL (P23234) fasta scores: E(): 0, 47.8% in 550 aa, and to Saccharomyces cerevisiae pyruvate decarboxylase isozyme 3 SW:DCP3_YEAST (P26263) fasta scores: E(): 0, 38.1% in 557 aa. Also similar to ML1696 and ML2083 from M. leprae. Contains Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzymes. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CBD6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2647530	2648948	.	-	0	Locus=ML2230c;Name=purB;Function=INVOLVED IN DE NOVO PURINE BIOSYNTHESIS (AT THE EIGHT STEP) [CATALYTIC ACTIVITY: 1-(5-PHOSPHORIBOSYL)-4-(N-SUCCINO-CARBOXAMIDE) -5-AMINOIMIDAZOLE = FUMARATE + 5'-PHOSPHORIBOSYL-5-AMINO-4-IMIDAZOLECARBOXAMIDE (ALSO CATALYZES: N6-(1,2-DICARBOXYETHYL)AMP = FUMARATE + AMP)].;Product=PROBABLE ADENYLOSUCCINATE LYASE PURB (ADENYLOSUCCINASE) (ASL) (ASASE);Comments=ML2230c, len: 472 aa. Probable purB, adenylosuccinate lyase (EC 4.3.2.2). Similar to Mycobacterium tuberculosis hypothetical 51.0 kda protein cy369.21b Rv0777 OR MTCY369.21B TR:P71832 (EMBL:Z80226) fasta scores: E(): 0, 86.4% identity in 472 aa, and to Saccharomyces cerevisiae adenylosuccinate lyase ADE13 OR YLR359W OR L8039.12 SW:PUR8_YEAST (Q05911) fasta scores: E(): 0, 34.5% identity in 449 aa. Contains Pfam match to entry PF00206 lyase_1, Lyase. Contains PS00163 Fumarate lyases signature.;UniProt_AC=Q9CBC1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2653344	2654612	.	-	0	Locus=ML2235c;Name=purD;Function=;Product=PROBABLE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PURD (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE) (5'-PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE);Comments=ML2235c, len: 422 aa. Probable purD, phosphoribosylamine-glycine ligase(EC 6.3.4.13). Similar to Mycobacterium tuberculosis phosphoribosylamine--glycine ligase PurD OR Rv0772 OR MTCY369.17 SW:PUR2_MYCTU (P71827) fasta scores: E(): 0, 81.8% identity in 418 aa, and to Salmonella typhimurium phosphoribosylamine--glycine ligase PurD SW:PUR2_SALTY (P26977) fasta scores: E(): 0, 43.2% identity in 426 aa. Contains Pfam match to entry PF01071 GARS, Phosphoribosylglycinamide synthetase (GARS). Contains PS00184 Phosphoribosylglycinamide synthetase signature.;UniProt_AC=Q50144;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2959468	2960016	.	-	0	Locus=ML2485c;Name=ML2485c;Function=;Product=POSSIBLE RNA METHYLTRANSFERASE (RNA METHYLASE);Comments=ML2485c, len: 182 aa. Possible RNA methyltransferase (EC 2.1.1.-). Similar to Mycobacterium tuberculosis hypothetical protein Rv0380c TR:O53715 (EMBL:AL021931) fasta scores: E(): 0, 89.0% identity in 182 aa, and to Escherichia coli SpoU SW:TRMH_ECOLI (P19396) fasta scores: E(): 6.1e-07, 26.2% identity in 164 aa. Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family.;UniProt_AC=Q9CB29;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2903588	2904682	.	-	0	Locus=ML2428c;Name=galE2;Function=;Product=POSSIBLE UDP-GLUCOSE 4-EPIMERASE GALE2 (GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHO-GALACTOSE 4-EPIMERASE);Comments=ML2428c, len: 364 aa. Possible galE2, UDP-glucose 4-epimerase (EC 5.1.3.2). Similar to Mycobacterium tuberculosis UDP-glucose 4-epimerase Rv0501 SW:Y501_MYCTU (Q11166) (376 aa) fasta scores: E(): 0, 84.0% identity in 368 aa, and to Streptomyces violaceoruber dTDP-glucose dehydratase TR:Q56173 (EMBL:L37334) (321 aa) fasta scores: E(): 2.9e-07, 30.4% identity in 332 aa.;UniProt_AC=P0A5D0,Q9CB57;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2904753	2904854	.	-	0	Locus=ML2428A;Name=ML2428A;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML2428A, len: 33 aa. Conserved hypothetical protein, strongly basic. Highly similar to M. tuberculosis Rv0500B (33 aa), fasta scores: E(): 3.4e-14, 100.000% identity  in 33 aa overlap. Also similar to Streptomyces coelicolor SCE68.25c, hypothetical protein, len : 32 aa unknown function, possible small, lysine-rich protein. FASTA scores: gp|AL079345|AL079345_25 Streptomyces coelicolor (32 aa) E(): 1.7e-07; 93.103% identity in 29 aa overlap;UniProt_AC=;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2909080	2910099	.	-	0	Locus=ML2434c;Name=ML2434c;Function=;Product=conserved hypothetical protein;Comments=ML2434c, len: 339 aa. Conserved hypothetical protein. Similar to many including: Mycobacterium tuberculosis hypothetical protein Rv0496 SW:Y496_MYCTU (Q11161) (328 aa) fasta scores: E(): 0, 85.6% identity in 327 aa. Also weakly similar to several exopolyphosphatases involved in the degradation of inorganic polyphosphates e.g. Escherichia coli exopolyphosphatase ppx SW:PPX_ECOLI (P29014) (512 aa) fasta scores: E(): 8.4e-09, 22.5% identity in 298 aa.;UniProt_AC=P54882;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2910203	2911036	.	+	0	Locus=ML2435;Name=ML2435;Function=;Product=conserved hypothetical protein;Comments=ML2435, len: 277 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0495c SW:Y495_MYCTU (Q11160) (296 aa) fasta scores: E(): 0, 82.7% identity in 271 aa, and to Streptomyces coelicolor hypothetical protein TR:Q9X8H2 (EMBL:AL049819) (271 aa) fasta scores: E(): 0, 48.4% identity in 250 aa.;UniProt_AC=P54579;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2915136	2916461	.	-	0	Locus=ML2440c;Name=senX3;Function=;Product=PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3;Comments=ML2440c, len: 441 aa. Probable senX3, two-component system sensor histidine kinase (EC 2.7.3.-). Similar to many proposed two-component sensor histiding kinases including: Mycobacterium tuberculosis sensor-like histidine kinase SenX3 Rv0490 SW:SEX3_MYCTU (Q11155) (410 aa) fasta scores: E(): 0, 84.0% identity in 406 aa, and to Mycobacterium bovis sensor-like histidine kinase SenX3 SW:SEX3_MYCBO (O07129) (410 aa) fasta scores: E(): 0, 83.7% identity in 406 aa. Contains Pfam match to entry PF00512 signal, Histidine kinase.;UniProt_AC=P54883;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2924649	2925464	.	+	0	Locus=ML2449;Name=ML2449;Function=;Product=POSSIBLE AMIDOHYDROLASE;Comments=ML2449, len: 271 aa. Possible amidohydrolase. Similar to several including: Mycobacterium tuberculosis amidohydrolase Rv0480c SW:Y480_MYCTU (Q11146) (280 aa), fasta scores: E(): 0, 81.9% identity in 270 aa, and to Streptomyces coelicolor putative hydrolase TR:Q9XA70 (EMBL:AL096822) fasta scores: E(): 1.5e-16, 34.9% identity in 272 aa. Contains Pfam match to entry PF00795 CN_hydrolase, Carbon-nitrogen hydrolase. Contains PS01227 Uncharacterized protein family UPF0012 signature.;UniProt_AC=Q9CB47;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2925770	2926507	.	+	0	Locus=ML2450;Name=ML2450;Function=;Product=possible secreted protein;Comments=ML2450, len: 245 aa. Possible secreted protein. Similar to the C-terminal region of Mycobacterium tuberculosis hypothetical protein Rv0479c SW:Y479_MYCTU (Q11145) (348 aa),  fasta scores: E(): 0, 70.0% identity in 243 aa. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CB46;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2947166	2948149	.	-	0	Locus=ML2472c;Name=tyrA;Function=;Product=PREPHENATE DEHYDROGENASE TYRA (PDH) (HYDROXYPHENYLPYRUVATE SYNTHASE);Comments=ML2472c, len: 327 aa. Probable tyrA, prephenate dehydrogenase (EC 1.3.1.12). Similar to Mycobacterium tuberculosis putative oxidoreductase Rv3754 TR:O69721 (EMBL:AL022121) fasta scores: E(): 0, 80.0% identity in 300 aa and to Bacillus subtilis prephenate dehydrogenase TyrA SW:TYRA_BACSU (P20692) fasta scores: E(): 1.6e-15, 29.1% identity in 285 aa. Contains Pfam match to entry PF02153 PDH, Prephenate dehydrogenase.;UniProt_AC=Q9CB34;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2930186	2930887	.	+	0	Locus=ML2457;Name=ML2457;Function=;Product=PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY);Comments=ML2457, len: 233 aa. Probable regulatory protein, possibly tetR family. Similar to several putative trancriptional regulators e.g. Mycobacterium tuberculosis putative regulatory protein Rv0472c TR:O53757 (EMBL:AL021933) fasta scores: E(): 0, 88.8% identity in 232 aa. Contains a helix-turn-helix motif situated between residues 45..66 (+3.77 SD).  Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family.;UniProt_AC=Q9CB41;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2969306	2969704	.	-	0	Locus=ML2493c;Name=hspR;Function=;Product=PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR (MERR FAMILY);Comments=ML2493c, len: 132 aa. Probable hspR, heat shock transcriptional repressor. Similar to Mycobacterium tuberculosis HspR OR Rv0353 TR:O06302 (EMBL:Z95324) fasta scores: E(): 0, 80.0% identity in 125 aa, and to Streptomyces albus TR:P96458 (EMBL:U43299) fasta scores: E(): 3.9e-20, 50.0% identity in 152 aa. Contains Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family.;UniProt_AC=Q9CB24;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2974628	2975287	.	+	0	Locus=ML2498;Name=ML2498;Function=;Product=possible enoyl-CoA hydratase;Comments=ML2498, len: 219 aa. Possible enoyl-CoA hydratase (EC 5.-.-.-). Similar to several proteins belonging to the enoyl-CoA hydratase/isomerase family e.g. Arabidopsis thaliana carnitine racemase homolog TR:O23300 (EMBL:Z97336) fasta scores: E(): 1.7e-17, 36.0% identity in 203 aa and Escherichia coli carnitine racemase CAID CAID_ECOLI|P31551|P75623 fasta scores: E(): 2.9e-08, 29.0% identity in 214 aa. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.;UniProt_AC=Q9CB21;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2987957	2988529	.	-	0	Locus=ML2507c;Name=dcd;Function=;Product=PROBABLE DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE DCD (DCTP DEAMINASE);Comments=ML2507c, len: 190 aa. Probable dcd, deoxycytidine triphosphate deaminase (EC 3.5.4.13).  Similar to Mycobacterium tuberculosis deoxycytidine triphosphate deaminase Rv0321 SW:DCD_MYCTU (O07247) fasta scores: E(): 0, 89.5% identity in 190 aa and to Escherichia coli deoxycytidine triphosphate deaminase SW:DCD_ECOLI (P28248) fasta scores: E(): 7.5e-20, 42.6% identity in 188 aa. Contains Pfam match to entry PF00692 dUTPase, dUTPase. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CB17;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2977471	2978043	.	+	0	Locus=ML2499A;Name=lpqJ;Function=;Product=Probable lipoprotein LpqJ;Comments=ML2499A, len: 190 aa. Hypothetical protein Similar to O06295|Rv0344c Probable lpqJ Lipoprotein from M. tuberculosis (186 aa), fasta scores: E(): 4e-38 (67.598% identity in 179 aa overlap). Has an appropriately positioned prokaryotic lipoprotein signature (PS00013).;UniProt_AC=;Is_Pseudogene=No;Functional_Category=cell wall and cell processes, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2977452	2978023	.	+	0	Locus=ML2499A;Name=lpqJ;Function=;Product=Probable lipoprotein LpqJ;Comments=ML2499A, len: 190 aa. Hypothetical protein Similar to O06295|Rv0344c Probable lpqJ Lipoprotein from M. tuberculosis (186 aa), fasta scores: E(): 4e-38 (67.598% identity in 179 aa overlap). Has an appropriately positioned prokaryotic lipoprotein signature (PS00013).;UniProt_AC=;Is_Pseudogene=No;Functional_Category=cell wall and cell processes, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3260985	3261764	.	-	0	Locus=ML2705c;Name=ML2705c;Function=;Product=conserved hypothetical protein;Comments=ML2705c, len: 259 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 26.6 kda protein Rv3916c TR:O53594 (EMBL:AL021426) fasta scores: E(): 0, 76.4% in 250 aa, and to Streptomyces coelicolor hypothetical 22.6 kda protein TR:Q9R3S2 (EMBL:AF187159) fasta scores: E(): 1e-08, 39.7% in 237 aa.;UniProt_AC=Q50200;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1283592	1284053	.	-	0	Locus=ML1109A;Name=ML1109A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1109A, len:461. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-34 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3053230	3053718	.	-	0	Locus=ML2561c;Name=ML2561c;Function=;Product=POSSIBLE OXIDOREDUCTASE;Comments=ML2561c, len: 162 aa. Possible oxidoreductase. Similar to many including: Mycobacterium tuberculosis Possible oxidoreductase Rv0245 OR MTV034.11 TR:O53667 (EMBL:AL021929) fasta scores: E(): 0, 82.0% identity in 161 aa and Streptomyces pristinaespiralis NADH:riboflavin 5'-phosphate oxidoreductase SNAC SW:SNAC_STRPR (P54994) fasta scores: E(): 2.7e-10, 31.6% identity in 158 aa. Contains Pfam match to entry PF01613 Flavin_Reduct, Flavin reductase like domain.;UniProt_AC=O69508;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3063966	3065129	.	-	0	Locus=ML2569c;Name=lpqI;Function=;Product=PROBABLE CONSERVED LIPOPROTEIN LPQI;Comments=ML2569c, len: 387 aa. Probable lpqI, conserved lipoprotein. Similar to several e.g. Mycobacterium tuberculosis conserved lipoprotein Rv0237 TR:O53660 (EMBL:AL021929) fasta scores: E(): 0, 73.2% identity in 392 aa. Also similar in regions to several beta-hexosaminidase e.g. Alteromonas sp SW:HEXA_ALTSO (P48823) fasta scores: E(): 4.1e-17, 30.0% identity in 333 aa. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.;UniProt_AC=O69499,Q9CD20;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3093776	3094816	.	+	0	Locus=ML2590;Name=mce1B;Function=;Product=MCE-FAMILY PROTEIN MCE1B;Comments=ML2590, len: 346 aa.  mce1B, Mce-family protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0170 TR:O07414 (EMBL:Z97050) fasta scores: E(): 0, 75.1% identity in 346 aa. Orthologue of M. tuberculosis mce1B (Rv0170). Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CD13;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	3096369	3097964	.	+	0	Locus=ML2592;Name=mce1D;Function=;Product=MCE-FAMILY PROTEIN MCE1D;Comments=ML2592, len: 531 aa. mce1D, Mce-family protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0172 TR:O07416 (EMBL:Z97050) fasta scores: E(): 0, 78.1% identity in 534 aa. Orthologue of M. tuberculosis Mce1D (Rv0172). Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CD11;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	3221704	3222414	.	+	0	Locus=ML2677;Name=ML2677;Function=;Product=PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN;Comments=ML2677, len: 236 aa.  Probable transcriptional regulatory protein (TetR-family). Similar to several putative transcriptional regulators including: Mycobacterium tuberculosis transcriptional regulator Rv0078 TR:O53623 (EMBL:AL021428) fasta scores: E(): 0, 71.4% in 175 aa, and Streptomyces coelicolor putative transcriptional regulatory protein TR:CAB76360 (EMBL:AL158061) fasta scores: E(): 0.048, 25.4% in 201 aa. Contains a probable helix-turn-helix motif at aa 35-56 (Score 1329, SD +3.71) Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family.;UniProt_AC=O53119;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1298899	1299416	.	+	0	Locus=ML1120A;Name=ML1120A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1120A, len:517. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-20 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2982840	2984153	.	+	0	Locus=ML2502;Name=aspC;Function=;Product=PROBABLE ASPARTATE AMINOTRANSFERASE ASPC (TRANSAMINASE A) (ASPAT);Comments=ML2502, len: 437 aa. Probable aspC, aspartate aminotransferase (EC 2.6.1.1). Similar to Mycobacterium tuberculosis probable aspartate aminotransferase Rv0337c SW:AAT_MYCTU (O33267) fasta scores: E(): 0, 91.4% identity in 429 aa and to Bacillus stearothermophilus aspartate aminotransferase AspC SW:AAT_BACST (Q59228) fasta scores: E(): 0, 32.4% identity in 389 aa. Contains Pfam match to entry PF00155 aminotran_1, Aminotransferases class-I.;UniProt_AC=Q9CB19;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2901524	2902450	.	+	0	Locus=ML2426;Name=cmaA2;Function=ESSENTIAL FOR THE CYCLOPROPANATION FUNCTION. TRANSFERS A METHYLENE GROUP FROM S-ADENOSYL-L-METHIONINE TO THE CIS DOUBLE BOND OF AN UNSATURATED FATTY ACID CHAIN RESULTING IN THE REPLACEMENT OF THE DOUBLE BOND WITH A METHYLENE BRIDGE. MYCOLIC ACIDS, WHICH REPRESENT THE MAJOR CONSTITUENT OF MYCOBACTERIAL CELL WALL COMPLEX, ACT AS SUBSTRATES [CATALYTIC ACTIVITY: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid].;Product=CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 2 CMAA2 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) (CYCLOPROPANE MYCOLIC ACID SYNTHASE 2) (MYCOLIC ACID TRANS-CYCLOPROPANE SYNTHETASE);Comments=ML2426, len: 308 aa. Probable cmaA2, cyclopropane mycolic acid synthase 2 (EC 2.1.1.79). Similar to Mycobacterium tuberculosis cyclopropane-fatty-acyl-phospholipid synthase Rv0503c SW:CFA2_MYCTU (Q11196) (302 aa) fasta scores: E(): 0, 78.9% identity in 303 aa. Also similar to ML2459 from M. leprae.;UniProt_AC=Q49807;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2971574	2973436	.	-	0	Locus=ML2496c;Name=dnaK;Function=;Product=PROBABLE CHAPERONE PROTEIN DNAK (HEAT SHOCK PROTEIN 70) (HEAT SHOCK 70 KDA PROTEIN) (HSP70);Comments=ML2496c, len: 620 aa. Probable dnaK, 70 kD heat shock protein (molecular chaperone) (EC 3.6.1.-). Similar to Mycobacterium paratuberculosis dnak protein SW:DNAK_MYCPA (Q00488) fasta scores: E(): 0, 93.4% identity in 622 aa, and to Mycobacterium tuberculosis dnak protein Rv0350 SW:DNAK_MYCTU (P32723; O06301) fasta scores: E(): 0, 92.5% identity in 624 aa. Contains Pfam match to entry PF00012 HSP70, Hsp70 protein. Contains PS01036 Heat shock hsp70 proteins family signature 3. Contains PS00329 Heat shock hsp70 proteins family signature 2. Contains PS00297 Heat shock hsp70 proteins family signature 1.;UniProt_AC=P19993;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	3057494	3058867	.	-	0	Locus=ML2564c;Name=fadA2;Function=;Product=PROBABLE ACETYL-CoA ACYLTRANSFERASE FADA2 (3-KETOACYL-CoA THIOLASE) (BETA-KETOTHIOLASE);Comments=ML2564c, len: 457 aa. Probable fadA2,acetyl-CoA acetyltransferase (EC ).  Similar to many Prokaryotic and Eukaryotic thiolases including: Escherichia coli probable 3-ketoacyl-coa thiolase YFCY SW:YFCY_ECOLI (P76503) fasta scores: E(): 0, 36.9% identity in 434 aa and to Rattus norvegicus trifunctonal enzyme beta subunit, mitochondrial precursor SW:ECHB_RAT (Q60587) fasta scores: E(): 0, 37.2% identity in 462 aa. Contains Pfam match to entry PF00108 thiolase, Thiolase. Contains PS00099 Thiolases active site.;UniProt_AC=O69505;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1306546	1306773	.	-	0	Locus=ML1125A;Name=ML1125A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1125A, len:227. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2921391	2922716	.	-	0	Locus=ML2446c;Name=lprQ;Function=;Product=PROBABLE CONSERVED LIPOPROTEIN LPRQ;Comments=ML2446c, len: 441 aa. Probable lprQ, conserved lipoprotein. Similar to Mycobacterium tuberculosis lipoprotein lprQ Rv0483  SW:Y483_MYCTU (Q11149) fasta scores: E(): 0, 79.3% identity in 439 aa, and to Streptomyces coelicolor putative lipoprotein TR:CAB76012 (EMBL:AL157916) fasta scores: E(): 2.5e-24, 28.6% identity in 405 aa. Also similar to ML0426 from M. leprae. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CB49;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3092454	3093779	.	+	0	Locus=ML2589;Name=mce1A;Function=;Product=MCE-FAMILY PROTEIN MCE1A;Comments=ML2589, len: 441 aa. Probable mce1A, Mce-family protein. Highly similar to Mycobacterium tuberculosis Mce proteins associated with entry and survival inside macrophage e.g. Rv0169 ORMTCI28.08 TR:P72013 (EMBL:Z97050) fasta scores: E(): 0, 67.5% identity in 456 aa.Orthologue of M. tuberculosis Mce1A (Rv0169). Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CD14;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	3204719	3209548	.	+	0	Locus=ML2671;Name=ctpI;Function=;Product=PROBABLE CATION-TRANSPORTER ATPASE I CTPI;Comments=ML2671, len: 1609 aa. Probable ctpI, cation transporter ATPase (EC 3.6.3.-). Similar to Mycobacterium tuberculosis Rv0107c|ctpI probable cation-transporting ATPase I SW:CTPI_MYCTU (Q10900) fasta scores: E(): 0, 81.9% in 1573 aa, and the C-terminal region is similar to to Synechococcus sp cation-transporting ATPase PacL SW:ATCL_SYNP7 (P37278) fasta scores: E(): 9.3e-26, 29.4% in 958 aa. Contains 2 Pfam matches to entry PF00122 E1-E2_ATPase, E1-E2 ATPase. Contains PS00154 E1-E2 ATPases phosphorylation site.;UniProt_AC=O53114;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3233193	3233447	.	-	0	Locus=ML2683c;Name=rpsR;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S18-1 RPSR;Comments=ML2683c, len: 84 aa. Probable rpsR, 30S ribosomal protein S18. Similar to Bacillus subtilis 30s ribosomal protein s18 SW:RS18_BACSU (P21475) fasta scores: E(): 7.3e-10, 51.5% in 68 aa, and to Mycobacterium tuberculosis 30s ribosomal protein s18-1 SW:R18A_MYCTU (P71712) fasta scores: E(): 1.5e-30, 90.5% in 84 aa. Contains Pfam match to entry PF01084 Ribosomal_S18, Ribosomal protein S18. Contains PS00057 Ribosomal protein S18 signature.;UniProt_AC=O53125;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	3145235	3145606	.	-	0	Locus=ML2630c;Name=ML2630c;Function=;Product=conserved hypothetical protein;Comments=ML2630c, len: 123 aa. Conserved hypothetical protein. Highly similar in part to another Mycobacterium leprae hypothetical protein ML0007 TR:O32870 (EMBL:Z70722) fasta scores: E(): 2.7e-28, 96.6% identity in 88 aa. Note this is a possible pseudogene likely to have been formed as a consequence of a duplication event. Also similar in part to P71575|Y007_MYCTU|Rv0007 Hypothetical protein from M. tuberculosis (304 aa), fasta scores: E():  1.1, (36.667% identity in 90 aa overlap).;UniProt_AC=O06091;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3131789	3132376	.	-	0	Locus=ML2621c;Name=ML2621c;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML2621c, len: 195 aa. Conserved hypothetical protein. Similar except shorter to Mycobacterium tuberculosis hypothetical protein Rv0207c TR:P96389 (EMBL:Z92669) fasta scores: E(): 0, 60.8% identity in 199 aa, and weakly similar to Schizosaccharomyces pombe hypothetical protein TR:O74960 (EMBL:AL023705) fasta scores: E(): 1, 22.2% id in 248 aa.;UniProt_AC=Q9CD00;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3232687	3233145	.	-	0	Locus=ML2682c;Name=rplI;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L9 RPLI;Comments=ML2682c, len: 152 aa. Probable rplI, 50S ribosomal protein L9. Similar to Mycobacterium tuberculosis 50s ribosomal protein l9 SW:RL9_MYCTU (P71713) fasta scores: E(): 0, 88.7% in 150 aa, and to Escherichia coli 50s ribosomal protein l9 SW:RL9_ECOLI (P02418) fasta scores: E(): 1.3e-12, 41.1% in 151 aa. Contains Pfam match to entry PF01281 Ribosomal_L9, Ribosomal protein L9. Contains PS00651 Ribosomal protein L9 signature.;UniProt_AC=P46385;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	3169333	3170148	.	-	0	Locus=ML2649c;Name=ML2649c;Function=;Product=Putative oligosaccharide deacetylase;Comments=ML2649c, len: 271 aa. Putative oligosaccharide deacetylase.  Weakly similar to others e.g. Streptomyces coelicolor putative oligosaccharide deacetylase TR:Q9RCX4 (EMBL:AL133469) fasta scores: E(): 4.5e-10, 30.9% in 165 aa, and to Bacillus cereus polysaccharide deacetylase-like protein TR:Q9XBJ5 (EMBL:AJ010139) fasta scores: E(): 2.4e-07, 26.6% in 241 aa. Contains Pfam match to entry PF01522 Polysac_deacet, Polysaccharide deacetylase. Contains PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.;UniProt_AC=Q9CCZ2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3100817	3101365	.	+	0	Locus=ML2595;Name=ML2595;Function=;Product=PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN;Comments=ML2595, len: 182 aa. Probable conserved Mce associated membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0175 TR:O07419 (EMBL:Z97050) fasta scores: E(): 0, 70.5% identity in 166 aa. Orthologue of M. tuberculosis Rv0175. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9CD08;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3101362	3102339	.	+	0	Locus=ML2596;Name=ML2596;Function=;Product=PROBABLE CONSERVED MCE ASSOCIATED TRANSMEMBRANE PROTEIN;Comments=ML2596, len: 325 aa. Probable conserved Mce associated transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0176 TR:O07420 (EMBL:Z97050) fasta scores: E(): 0, 54.9% identity in 319 aa. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CD07;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3107555	3108394	.	+	0	Locus=ML2603;Name=ML2603;Function=;Product=POSSIBLE LYSOPHOSPHOLIPASE;Comments=ML2603, len: 279 aa. Possible lysophospholipase (EC 3.1.-.-). Similar to Mycobacterium tuberculosis possible lysophospholipase Rv0183 TR:O07427 (EMBL:Z97050) fasta scores: E(): 0, 74.9% identity in 279 aa, and to several putative lipases e.g. Deinococcus radiodurans TR:Q9RU57 (EMBL:AE001997) fasta scores: E(): 2.1e-27, 36.4% identity in 275 aa.;UniProt_AC=Q9CD03;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3122276	3122788	.	-	0	Locus=ML2616c;Name=ML2616c;Function=;Product=conserved hypothetical protein;Comments=ML2616c, len: 170 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0201c TR:O53652 (EMBL:AL021928) fasta scores: E(): 0, 63.9% identity in 158 aa. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign.;UniProt_AC=O06078;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1323065	1323295	.	+	0	Locus=ML1131A;Name=ML1131A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1131A, len:230. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-19 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3126443	3127501	.	-	0	Locus=ML2618c;Name=ML2618c;Function=;Product=probable integral membrane protein;Comments=ML2618c, len: 352 aa. Probable integral membrane protein. Similar to several proteins of undefined function including: Mycobacterium tuberculosis Rv0204c TR:O53655 (EMBL:AL021928) fasta scores: E(): 0, 82.6% identity in 374 aa, and to Methanobacterium thermoautotrophicum SW:YC61_METTH (O27329) fasta scores: E(): 0.00014, 24.7% identity in 324 aa. Contains a possible N-terminal signal sequence and several other possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CD01;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3153219	3154322	.	-	0	Locus=ML2636c;Name=pntAa;Function=;Product=PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT ALPHA) PNTAA [FIRST PART; CATALYTIC PART] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA);Comments=ML2636c, len: 367 aa. Probable pntAa, pyridine transhydrogenase subunit [alpha]1 (EC 1.6.1.2). Similar to Mycobacterium tuberculosis PntAa OR Rv0155 TR:P96832 (EMBL:Z92770) fasta scores: E(): 0, 87.9% identity in 365 aa, Haemophilus influenzae NAD PntA SW:PNTA_HAEIN (P43842) fasta scores: E(): 0, 42.6% identity in 364 aa, and to Escherichia coli NAD PntA SW:PNTA_ECOLI (P07001; P76888) fasta scores: E(): 0, 42.1% identity in 363 aa. Contains Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase.;UniProt_AC=Q9CCZ6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3152888	3153226	.	-	0	Locus=ML2635c;Name=pntAb;Function=;Product=PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT ALPHA) PNTAB [SECOND PART; INTEGRAL MEMBRANE PROTEIN] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA);Comments=ML2635c, len: 112 aa. Probable pntAB, pyridine transhydrogenase subunit [alpha]2 (EC 1.6.1.2). Similar to Mycobacterium tuberculosis PntAB OR Rv0156 TR:P96833 (EMBL:Z92770) fasta scores: E(): 3.5e-30, 83.0% identity in 100 aa, and to Rhodospirillum rubrum nicotinamide nucleotide transhydrogenase, subunit alpha 2 PntAB TR:Q59764 (EMBL:U01158) fasta scores: E(): 6.1e-11, 42.7% identity in 89 aa. Note this is the equivalent to the very C-terminal hydrophobic domain of the larger E. coli and bovine mitochondrial enzymes. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase.;UniProt_AC=Q9CCZ7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3151473	3152891	.	-	0	Locus=ML2634c;Name=pntB;Function=;Product=PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT BETA) PNTB [INTEGRAL MEMBRANE PROTEIN] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT BETA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT BETA);Comments=ML2634c, len: 472 aa. Probable pntB, pyridine transhydrogenase subunit [beta] (EC 1.6.1.1). Similar to Mycobacterium tuberculosis PntB OR Rv0157 TR:P96834 (EMBL:Z92770) fasta scores: E(): 0, 87.3% identity in 473 aa, Rhodospirillum rubrum nicotinamide nucleotide transhydrogenase, subunit beta PntB TR:Q59765 (EMBL:U01158) fasta scores: E(): 0, 46.5% identity in 469 aa and to Escherichia coli NAD PntB SW:PNTB_ECOLI (P07002; P76890) fasta scores: E(): 0, 43.5% identity in 476 aa.;UniProt_AC=Q9CCZ8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1329874	1329957	.	+	0	Locus=ML1137A;Name=ML1137A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1137A, len:83. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3182083	3183147	.	-	0	Locus=ML2659c;Name=pepA;Function=;Product=PROBABLE SERINE PROTEASE PEPA (SERINE PROTEINASE) (MTB32A);Comments=ML2659c, len: 354 aa. Probable pepA, secreted serine protease (EC 3.4.21.-). Similar to many including: Mycobacterium paratuberculosis serine protease Rv0125 TR:Q50320 (EMBL:Z23092) fasta scores: E(): 0, 71.4% in 364 aa, Mycobacterium tuberculosis hypothetical 34.9 kda protein TR:O07175 (EMBL:Z96071) fasta scores: E(): 0, 70.1% in 358 aa, and to Escherichia coli protease DegS precursor SW:DEGS_ECOLI (P31137) fasta scores: E(): 2.1e-16, 32.0% in 356 aa. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00089 trypsin, Trypsin. Contains Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF).;UniProt_AC=Q9CCY9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3233473	3233979	.	-	0	Locus=ML2684c;Name=ssb;Function=;Product=PROBABLE SINGLE-STRAND BINDING PROTEIN SSB (HELIX-DESTABILIZING PROTEIN);Comments=ML2684c, len: 168 aa. Probable ssb, single strand binding protein. Similar to Escherichia coli single-strand binding protein SW:SSB_ECOLI (P02339) fasta scores: E(): 1.4e-09, 32.6% in 172 aa, and to Mycobacterium tuberculosis single-strand binding protein Rv0054 SW:SSB_MYCTU (P71711) fasta scores: E(): 0, 89.3% in 168 aa. Contains Pfam match to entry PF00436 SSB, Single-strand binding protein family.;UniProt_AC=P46390;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	3246791	3247522	.	+	0	Locus=ML2696;Name=ML2696;Function=;Product=POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY MARR-FAMILY);Comments=ML2696, len: 243 aa. POssible transcriptional regulatory protein (MarR-family). Similar to Mycobacterium tuberculosis Rv0042c transcriptional regulatory protein TR:P71699 (EMBL:Z80775) fasta scores: E(): 0, 77.4% in 190 aa, and weakly similar to Streptomyces coelicolor putative MarR-family transcriptional regulator TR:CAB76343 (EMBL:AL158061) fasta scores: E(): 1.9e-07, 32.7% in 147 aa. Contains Pfam match to entry PF01047 MarR, MarR family.;UniProt_AC=Q9CCY2;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	3190784	3191539	.	+	0	Locus=ML2664;Name=ldt;Function=;Product=POSSIBLE CONSERVED MEMBRANE PROTEIN;Comments=ML2664, len: 251 aa. Possible conserved membrane protein. Similar to Mycobacterium tuberculosis Rv0116c hypothetical 26.9 kda protein TR:O53638 (EMBL:AL021926) fasta scores: E(): 0, 76.0% in 250 aa, and to Streptomyces coelicolor putative secreted protein TR:Q9X811 (EMBL:AL049497) fasta scores: E(): 6.1e-21, 39.7% in 239 aa. Contains a possible N-terminal signal sequence and another possible membrane-spanning hydrophobic domain.;UniProt_AC=Q9ZBE6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3132585	3133277	.	-	0	Locus=ML2622c;Name=ML2622c;Function=;Product=Probable tRNA (guanine-N(7)-)-methyltransferase (tRNA(m7G46)-methyltransferase );Comments=ML2622c, len: 230 aa. Probable tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33). Similar to several e.g. Mycobacterium tuberculosis Rv0208c TR:P96390 (EMBL:Z92669) fasta scores: E(): 0, 64.2% identity in 246 aa, and to Neisseria meningitidis TR:AAF41703 (EMBL:AE002481) fasta scores: E(): 6e-25, 34.9% identity in 232 aa. Belongs to the methyltransferase superfamily. TrmB family. ;UniProt_AC=Q9CCZ9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1375734	1375918	.	+	0	Locus=ML1178A;Name=ML1178A;Function=;Product=fadA3; acetyl-CoA C-acetyltransferase(pseudogene);Comments=ML1178A, len:184. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-33 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3157371	3158876	.	-	0	Locus=ML2639c;Name=ML2639c;Function=;Product=PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT ;Comments=ML2639c, len: 501 aa. Probable aldehyde dehydrogenase (EC 1.2.1.-). Similar to many Prokaryotic and Eukaryotic aldehyde dehydrogenases including: Mycobacterium tuberculosis hypothetical 55.0 kda protein Rv0147 TR:P96824 (EMBL:Z92770) fasta scores: E(): 0, 77.1% identity in 493 aa and Homo sapiens aldehyde dehydrogenase, dimeric NADP-preferring ALDH3 SW:DHAP_HUMAN (P30838) fasta scores: E(): 0, 44.7% identity in 450 aa. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase family. Contains PS00687 Aldehyde dehydrogenases glutamic acid active site.;UniProt_AC=Q9CCZ5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	508328	508630	.	+	0	Locus=ML0410;Name=PE3;Function=;Product=PE-family protein;Comments=ML0410, len: 100 aa. Member of the Mycobacteria PE family. Similar to numerous M. tuberculosis PE-family proteins e.g. Rv2107|O33243|AL123456 PE-family protein (98 aa), Fasta scores: E(): 4.7e-08, (44.7% identity in 85 aa overlap). Also similar to ML0538, ML1183 and ML1414 from M. leprae. Contains Pfam match to entry PF00934 PE, PE family.;UniProt_AC=Q49724;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	1382329	1382628	.	-	0	Locus=ML1183c;Name=PE6;Function=;Product=PE FAMILY PROTEIN;Comments=ML1183c, len: 99 aa. Member of Mycobacteria PE family. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49943 (EMBL:AL049191) (99 aa), Fasta scores: E(): 0, 100.0% identity in 99 aa overlap. Also highly similar to many Mycobacterium tuberculosis PE family proteins e.g. TR:O05297 (EMBL:Z93777) Rv1195 (99 aa), Fasta scores: E(): 1.3e-12, 48.9% identity in 92 aa overlap and the N-terminus of several PGRS-family proteins also from M. tuberculosis e.g. Rv0742 TR:O53805 (EMBL:AL021958) (175 aa), Fasta scores: E(): 8.8e-09, 39.6% identity in 96 aa overlap. Also similar to ML1053 a possible orthologue of M. tuberculosis Rv1195. Contains Pfam match to entry PF00934 PE, PE family.;UniProt_AC=Q49943;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	3166874	3167407	.	+	0	Locus=ML2647;Name=msrA;Function=HAS AN IMPORTANT FUNCTION AS A REPAIR ENZYME FOR PROTEINS THAT HAVE BEEN INACTIVATED BY OXIDATION. CATALYZES THE REVERSIBLE OXIDATION-REDUCTION OF METHIONINE SULFOXIDE IN PROTEINS TO METHIONINE [CATALYTIC ACTIVITY: Protein L-methionine + oxidized thioredoxin = protein L-methionine S-oxide + reduced thioredoxin].;Product=PROBABLE PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA (PROTEIN-METHIONINE-S-OXIDE REDUCTASE) (PEPTIDE MET(O) REDUCTASE);Comments=ML2647, len: 177 aa. Probable msrA, peptide methionine sulfoxide reductase (EC 1.8.4.6). Similar to regions of several methionine sulfoxide reductases including: Pseudomonas fluorescens putative methionine sulfoxide reductase TR:O69761 (EMBL:L49465) fasta scores: E(): 0, 70.0% in 160 aa, and to Mycobacterium tuberculosis hypothetical 20.5 kda protein Rv0137c TR:P96814 (EMBL:Z92770) fasta scores: E(): 0, 80.0% in 170 aa, and to Escherichia coli peptide methionine sulfoxide reductase SW:PMSR_ECOLI (P27110) fasta scores: E(): 3e-25, 48.4% in 155 aa. Contains Pfam match to entry PF01625 PMSR, Peptide methionine sulfoxide reductase.;UniProt_AC=Q9CCZ3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3135283	3137112	.	+	0	Locus=ML2624;Name=pckA;Function=;Product=PROBABLE IRON-REGULATED PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP] PCKA (PHOSPHOENOLPYRUVATE CARBOXYLASE) (PEPCK)(PEP CARBOXYKINASE) ;Comments=ML2624, len: 609 aa. Probable pckA, iron-regulated phosphoenolpyruvate carboxykinase (EC 4.1.1.32). Similar to many Prokaryotic and Eukaryotic phosphoenolpyruvate carboxykinases including: Mycobacterium tuberculosis Rv0211 SW:PPCK_MYCTU (P96393) fasta scores: E(): 0, 86.1% identity in 605 aa, Chlorobium limicola SW:PPCK_CHLLI (Q08262) fasta scores: E(): 0, 56.1% identity in 592 aa and to Rattus norvegicus SW:PPCC_RAT (P07379) fasta scores: E(): 0, 50.3% identity in 624 aa. Contains Pfam match to entry PF00821 PEPCK, Phosphoenolpyruvate carboxykinase. Contains PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature.;UniProt_AC=O06084;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3236668	3238794	.	-	0	Locus=ML2688c;Name=ponA1;Function=INVOLVED IN PEPTIDOGLYCAN SYNTHESIS (AT THE FINAL STAGES), CELL WALL FORMATION. SYNTHESIS OF CROSS-LINKED PEPTIDOGLYCAN FROM THE LIPID INTERMEDIATES. THE ENZYME HAS A PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE N-TERMINAL DOMAIN (FORMATION OF LINEAR GLYCAN STRANDS) AND A PENICILLIN-SENSITIVE TRANSPEPTIDASE C-TERMINAL DOMAIN (CROSS-LINKING OF THE PEPTIDE SUBUNITS).;Product=PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE (PEPTIDOGLYCAN TGASE) + PENICILLIN-SENSITIVE TRANSPEPTIDASE (DD-TRANSPEPTIDASE);Comments=ML2688c, len: 708 aa. Probable ponA1, bifunctional penicillin-binding protein 1a/1b (EC 2.4.2.-; 3.4.-.-). Similar to Mycobacterium tuberculosis probable penicillin-binding proteins 1a/1b TR:P71707 (EMBL:Z80775) fasta scores: E(): 0, 82.6% in 679 aa, and to Bacillus subtilis penicillin-binding proteins 1a/1b SW:PBPA_BACSU (P39793) fasta scores: E(): 3.6e-28, 27.0% in 688 aa. Contains Pfam match to entry PF00912 Transglycosyl, Transglycosylase. Contains Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain.;UniProt_AC=Q9CCY4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1220377	1220676	.	+	0	Locus=ML1053;Name=PE5;Function=;Product=PE FAMILY PROTEIN;Comments=ML1053, len: 99 aa. Member of PE family protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49943 (EMBL:U15180) (99 aa), Fasta scores: E(): 0, 100.0% identity in 99 aa overlap. Also highly similar to the whole or just the N-terminus of many Mycobacterium tuberculosis PE-family proteins e.g. Rv1195 O05297 (111 aa), fasta scores:  E(): 5.8e-13 (48.913% identity in 92 aa overlap) and TR:P71664 (EMBL:Z80108) (576 aa), Fasta scores: E(): 3.2e-10, 44.6% identity in 92 aa overlap. Also similar to ML1183c a possible paralogue of M. tuberculosis Rv1195.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	1229651	1230631	.	+	0	Locus=ML1064;Name=gpgS;Function=;Product=conserved hypothetical protein;Comments=ML1064, len: 326 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49955 (EMBL:U15180) (318 aa), Fasta scores: E(): 0, 100.0% identity in 317 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1208 TR:O05309 (EMBL:Z93777) (324 aa), Fasta scores: E(): 0, 79.8% identity in 327 aa overlap.;UniProt_AC=Q9CCA9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1575497	1575688	.	+	0	Locus=ML1321;Name=pup;Function=;Product=conserved hypothetical protein;Comments=ML1321, len: 63 aa. Conserved hypothetical protein. Highly similar to many proteins of undefined function found upstream of bacterial proteasome beta subunits including: Mycobacterium smegmatis TR:O30517 (EMBL:AF009645) (64 aa), Fasta scores: E(): 6.2e-18, 82.8% identity in 64 aa overlap, Rhodococcus sp. TR:Q53082 (EMBL:U26422) (64 aa), Fasta scores: E(): 6.7e-17, 82.8% identity in 64 aa overlap and Mycobacterium tuberculosis Rv2111c TR:O33246 (EMBL:Z97559) (64 aa), Fasta scores: E(): 7.9e-19, 87.5% identity in 64 aa overlap. Note the high number of the amino acids Glu, Asp and Gly. Contains a possible coiled-coil region.;UniProt_AC=Q9ZBE0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1573921	1575465	.	+	0	Locus=ML1320;Name=dop;Function=;Product=conserved hypothetical protein;Comments=ML1320, len: 514 aa. Conserved hypothetical protein. Highly similar to many proteins of undefined function including: Rhodococcus sp. TR:Q53081 (EMBL:U26422) (499 aa), Fasta scores: E(): 0, 83.5% identity in 502 aa overlap and Mycobacterium tuberculosis Rv2112c TR:O33247 (EMBL:Z97559) (554 aa), Fasta scores: E(): 0, 95.4% identity in 504 aa overlap.;UniProt_AC=Q49779;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	503218	504402	.	+	0	Locus=ML0405;Name=espA;Function=;Product=Conserved hypothetical protein;Comments=ML0405, len: 394 aa. Conserved hypothetical protein, highly similar to Rv3616c|O06267|AL123456 conserved hypothetical protein from M. tuberculosis (392 aa), Fasta scores: E(): 0, (62.7% identity in 394 aa overlap) and similar to Rv3864|P96213|AL123456 hypothetical protein from M. tuberculosis (402 aa), Fasta scores: E(): 2.1e-15, (31.0% identity in 410 aa overlap). Previously sequenced as Q49722|U00015 (394 aa), Fasta scores: E(): 0, (100.0% identity in 394 aa overlap).;UniProt_AC=Q49722;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	58020	59558	.	-	0	Locus=ML0047c;Name=eccD1;Function=;Product=ESX CONSERVED COMPONENT ECCD1. PROBABLE TRANSMEMBRANE PROTEIN.;Comments=ML0047c, len: 512 aa. esx conserved component, probable transmembrane protein, highly similar to M. tuberculosis probable membrane proteins e.g. Rv3877|O69741|AL123456 transmembrane protein (511 aa), Fasta scores: 74.0% identity in 512 aa overlap. Similarity is weaker to Rv1795|O53944|AL123456 probable membrane protein (503 aa), Fasta scores: E(): 2.1e-13, (22.7% identity in 519 aa overlap) and Rv0290|O86362|AL123456 hydrophobic protein (472 aa), Fasta scores: E(): 2.4e-11, (26.6% identity in 512 aa overlap). Also similar to ML1539 and ML2529 from M. leprae. Previously sequenced as O33081|Y14967 (480 aa), Fasta scores: E(): 0, (100.0% identity in 480 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDD9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3011718	3013175	.	-	0	Locus=ML2529c;Name=eccD3;Function=;Product=ESX CONSERVED COMPONENT ECCD3. PROBABLE TRANSMEMBRANE PROTEIN.;Comments=ML2529c, len: 485 aa. esx conserved component, probable transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0290 TR:O86362 (EMBL:AL021930) fasta scores: 76.4% identity in 471 aa, and to Streptomyces coelicolor putative integral membrane protein SC3C3.21 TR:O86654 (EMBL:AL031231) fasta scores: E(): 1.9e-05, 23.8% identity in 483 aa. Contains multiple possible membrane spanning hydrophobic domains towards the C-terminus.;UniProt_AC=Q9CD35;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	51993	53396	.	+	0	Locus=ML0042;Name=eccE1;Function=;Product=ESX CONSERVED COMPONENT ECCE1. POSSIBLE MEMBRANE PROTEIN.;Comments=ML0042, len: 467 aa. Possible conserved membrane protein, highly similar to Rv3882c|O05462|AL123456 conserved membrane protein from M. tuberculosis (462 aa), Fasta scores: E(): 0, (72.1% identity in 462 aa overlap). Shows weak similarity to O05459|AL123456 hypothetical protein from M.tuberculosis (537 aa), Fasta scores: E(): 3.1e-09, (28.0% identity in 382 aa overlap). Also shows weak similarity to ML1537. Previously sequenced as O33077|Y14967 (467 aa), Fasta scores: E(): 0, (100.0% identity in 467 aa overlap). Contains hydrophobic, possible membrane-spanning regions near the N-terminus.;UniProt_AC=O33077;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1376133	1377067	.	+	0	Locus=ML1178B;Name=ML1178B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1178B, len:934. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-32 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	504460	504780	.	+	0	Locus=ML0406;Name=espC;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPC;Comments=ML0406, len: 106 aa. ESX-1 secretion-associated protein, highly similar to Rv3615c|O06268|AL123456 ESX-1 secretion-associated protein from M. tuberculosis (103 aa), Fasta scores: E(): 4.1e-19, (60.9% identity in 92 aa overlap) and similar to Rv3865|P96212|AL123456, protein from M. tuberculosis (103 aa), Fasta scores: E(): 0.00022, (31.1% identity in 103 aa overlap). Previously sequenced as Q49723|U00015 (106 aa), Fasta scores: (100.0% identity in 106 aa overlap).;UniProt_AC=Q49723;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	70584	71093	.	-	0	Locus=ML0056c;Name=espH;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPH;Comments=ML0056c, len: 169 aa. ESX-1 secretion-associated protein, similar to several proteins in M. tuberculosis e.g. Rv3867|O06269|AL123456 ESX-1 secretion-associated protein (184 aa), Fasta scores: E(): 1.1e-12, (38.4% identity in 172 aa overlap); and Rv3614c|O69732|AL123456 protein (183 aa), Fasta scores: E(): 1e-20, (48.2% identity in 166 aa overlap). Also similar to ML0407 from M. leprae. Previously sequenced as Q49730|U00015 (216 aa), Fasta scores: E(): 1.7e-13, (40.2% identity in 169 aa overlap.);UniProt_AC=Q9CDD6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	59555	61315	.	-	0	Locus=ML0048c;Name=espI;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPI. CONSERVED PROLINE AND ALANINE RICH PROTEIN.;Comments=ML0048c, len: 586 aa. ESX-1 secretion-associated protein, conserved pro-, ala-rich protein. Similar to several proteins from M. tuberculosis, some of which also contain proline-rich regions e.g. Rv3876|O69740|AL123456 pro-, ala-rich protein (666 aa), Fasta scores: (50.7% identity in 672 aa overlap); and Rv0530|O06396|AL123456 hypothetical protein (405 aa), Fasta scores: E(): 1.3e-19, (30.5% identity in 417 aa overlap). Similar to the C-terminal half of O86637|AL031231 hypothetical protein SC3C3.03C from Streptomyces coelicolor (1083 aa), Fasta scores: E(): 5.9e-27, (31.6% identity in 580 aa overlap), which contains Pro-Gln repeats. C-terminal half is similar to that of ML0798. Previously sequenced as O33082|Y14967 (478 aa), Fasta scores: (100.0% identity in 478 aa overlap).;UniProt_AC=Q9CDD8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	54698	55039	.	+	0	Locus=ML0044;Name=espL;Function=;Product=ESX-1 SECRETION-ASSOCIATED PROTEIN ESPL;Comments=ML0044, len: 113 aa. ESX-1 secretion-associated protein, highly similar to Rv3880c|O69744|AL123456 ESX-1 secretion-associated protein from M. tuberculosis (115 aa), Fasta scores: E(): 2.6e-21, (56.4% identity in 110 aa overlap). Previously sequenced as O33080|Y14967 (113 aa), Fasta scores: (100.0% identity in 113 aa overlap).;UniProt_AC=O33080;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	83900	84046	.	+	0	Locus=ML0062A;Name=ML0062A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0062A, len:146. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-17 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	84112	84676	.	-	0	Locus=ML0062B;Name=ML0062B;Function=;Product=hypothetical protein(pseudogene);Comments=ML0062B, len:564. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-30 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	91560	91641	.	-	0	Locus=ML0070A;Name=ML0070A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0070A, len:81. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-04 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	93497	93592	.	-	0	Locus=ML0072A;Name=ML0072A;Function=;Product=hypothetical protein(pseudogene);Comments=ML0072A, len:95. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 6.00E-11 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1533805	1534116	.	-	0	Locus=ML1287A;Name=ML1287A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1287A, len:311. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1552382	1552510	.	-	0	Locus=ML1303A;Name=ML1303A;Function=;Product=probable conserved transmembrane protein(pseudogene);Comments=ML1303A, len:128. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1564256	1565016	.	+	0	Locus=ML1311A;Name=ML1311A;Function=;Product=lpd; similar to mercury(II) reductase(pseudogene);Comments=ML1311A, len:760. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-55 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1603360	1603476	.	-	0	Locus=ML1344A;Name=ML1344A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1344A, len:116. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.025 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1635899	1636015	.	+	0	Locus=ML1374A;Name=ML1374A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1374A, len:116. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.001 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1639014	1639343	.	+	0	Locus=ML1375A;Name=ML1375A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1375A, len:329. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-18 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1645736	1646507	.	-	0	Locus=ML1380A;Name=ML1380A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1380A, len:771. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-45 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1646508	1646633	.	-	0	Locus=ML1380B;Name=ML1380B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1380B, len:125. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1646678	1647268	.	-	0	Locus=ML1380C;Name=ML1380C;Function=;Product=hypothetical protein(pseudogene);Comments=ML1380C, len:590. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-23 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1655574	1655788	.	-	0	Locus=ML1383A;Name=ML1383A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1383A, len:214. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-14 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1656073	1656225	.	-	0	Locus=ML1383B;Name=ML1383B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1383B, len:152. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-12 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1671277	1671399	.	-	0	Locus=ML1392A;Name=ML1392A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1392A, len:122. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.001 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1718738	1719268	.	+	0	Locus=ML1432A;Name=ML1432A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1432A, len:530. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-23 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1719817	1720120	.	-	0	Locus=ML1433B;Name=ML1433B;Function=;Product=putative gluconokinase(pseudogene);Comments=ML1433B, len:303. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-13 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1745023	1745178	.	+	0	Locus=ML1450B;Name=ML1450B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1450B, len:155. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 9.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1746224	1746877	.	-	0	Locus=ML1451D;Name=ML1451D;Function=;Product=hypothetical protein(pseudogene);Comments=ML1451D, len:653. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = e-108 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1818445	1818573	.	-	0	Locus=ML1506A;Name=ML1506A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1506A, len:128. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-07 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1844957	1845357	.	-	0	Locus=ML1529A;Name=ML1529A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1529A, len:400. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1850216	1850368	.	-	0	Locus=ML1533A;Name=ML1533A;Function=;Product=PPE family protein(pseudogene);Comments=ML1533A, len:152. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1850352	1850701	.	-	0	Locus=ML1533B;Name=ML1533B;Function=;Product=PPE family protein(pseudogene);Comments=ML1533B, len:349. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1859295	1859396	.	-	0	Locus=ML1540A;Name=ML1540A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1540A, len:101. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.40E-02 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1900488	1900560	.	-	0	Locus=ML1575A;Name=ML1575A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1575A, len:72. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 6.00E-13 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1958580	1958798	.	-	0	Locus=ML1629A;Name=ML1629A;Function=;Product=acylphosphatase(pseudogene);Comments=ML1629A, len:164. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.002 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1958574	1958738	.	-	0	Locus=ML1629A;Name=ML1629A;Function=;Product=acylphosphatase(pseudogene);Comments=ML1629A, len:164. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.002 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1971857	1972192	.	+	0	Locus=ML1636A;Name=ML1636A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1636A, len:335. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-43 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1972409	1972524	.	+	0	Locus=ML1636B;Name=ML1636B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1636B, len:115. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 9.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1999765	1999887	.	-	0	Locus=ML1657A;Name=ML1657A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1657A, len:122. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 6.00E-07 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1999885	1999932	.	+	0	Locus=ML1657B;Name=ML1657B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1657B, len:47. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-03 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2041275	2041766	.	+	0	Locus=ML1693A;Name=ML1693A;Function=;Product=putative Trp repressor binding protein(pseudogene);Comments=ML1693A, len:491. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-44 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2051748	2051904	.	-	0	Locus=ML1700A;Name=ML1700A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1700A, len:156. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.033 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2059383	2059591	.	-	0	Locus=ML1706A;Name=ML1706A;Function=;Product=PPE family protein(pseudogene);Comments=ML1706A, len:208. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 6.00E-04 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2071252	2071353	.	+	0	Locus=ML1716A;Name=ML1716A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1716A, len:101. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-08 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2097381	2097452	.	-	0	Locus=ML1736A;Name=ML1736A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1736A, len:71. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 6.00E-04 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2105689	2105847	.	+	0	Locus=ML1744A;Name=ML1744A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1744A, len:158. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2119474	2120181	.	-	0	Locus=ML1751A;Name=ML1751A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1751A, len:710. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-96 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=conserved hypotheticals, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2119853	2120563	.	-	0	Locus=ML1751A;Name=ML1751A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1751A, len:710. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-96 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=conserved hypotheticals, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2122905	2123066	.	+	0	Locus=ML1752A;Name=ML1752A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1752A, len:161. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-12 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2166241	2166545	.	-	0	Locus=ML1790A;Name=ML1790A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1790A, len:304. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2169842	2170343	.	+	0	Locus=ML1793A;Name=ML1793A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1793A, len:501. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 6.00E-14 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2172974	2173242	.	+	0	Locus=ML1794A;Name=ML1794A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1794A, len:268. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-04 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2176405	2176794	.	-	0	Locus=ML1798A;Name=ML1798A;Function=;Product=lipL; probable esterase(pseudogene);Comments=ML1798A, len:389. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-16 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2216985	2217599	.	-	0	Locus=ML1830A;Name=ML1830A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1830A, len:614. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-68 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2218026	2218595	.	-	0	Locus=ML1830B;Name=ML1830B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1830B, len:569. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-39 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2219124	2219201	.	-	0	Locus=ML1830D;Name=ML1830D;Function=;Product=sigL; RNA polymerase sigma-70 factor, ECF subfamily(pseudogene);Comments=ML1830D, len:77. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2282072	2282221	.	+	0	Locus=ML1897A;Name=ML1897A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1897A, len:149. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2288848	2289321	.	+	0	Locus=ML1903A;Name=ML1903A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1903A, len:473. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-08 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2289455	2290228	.	+	0	Locus=ML1903B;Name=ML1903B;Function=;Product=probable sigma-70 factor, ECF subfamily(pseudogene);Comments=ML1903B, len:773. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-27 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2300442	2300600	.	-	0	Locus=ML1916A;Name=ML1916A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1916A, len:158. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-08 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2306879	2307403	.	-	0	Locus=ML1923A;Name=ML1923A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1923A, len:524. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-13 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2307461	2308078	.	-	0	Locus=ML1923B;Name=ML1923B;Function=;Product=hypothetical protein(pseudogene);Comments=ML1923B, len:617. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-13 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2308197	2308286	.	-	0	Locus=ML1923C;Name=ML1923C;Function=;Product=hypothetical protein(pseudogene);Comments=ML1923C, len:89. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 9.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2356549	2356902	.	-	0	Locus=ML1972A;Name=ML1972A;Function=;Product=hypothetical protein(pseudogene);Comments=ML1972A, len:353. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-29 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2365062	2365142	.	-	0	Locus=ML1980A;Name=ML1980A;Function=;Product=tpx; thiol peroxidase(pseudogene);Comments=ML1980A, len:80. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2394357	2394449	.	+	0	Locus=ML2001A;Name=ML2001A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2001A, len:92. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2394520	2394887	.	+	0	Locus=ML2001B;Name=ML2001B;Function=;Product=hypothetical protein(pseudogene);Comments=ML2001B, len:367. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-25 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2428506	2428967	.	-	0	Locus=ML2037A;Name=ML2037A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2037A, len:461. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-16 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2430197	2430352	.	+	0	Locus=ML2038A;Name=ML2038A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2038A, len:155. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-12 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2430491	2430670	.	-	0	Locus=ML2038B;Name=ML2038B;Function=;Product=putative enoyl-CoA hydratase/isomerase(pseudogene);Comments=ML2038B, len:179. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-09 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2438066	2438367	.	+	0	Locus=ML2048A;Name=ML2048A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2048A, len:301. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-14 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2483062	2483178	.	+	0	Locus=ML2088A;Name=ML2088A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2088A, len:116. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2526724	2526795	.	-	0	Locus=ML2125A;Name=ML2125A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2125A, len:71. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.014 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2546242	2547030	.	-	0	Locus=ML2144A;Name=ML2144A;Function=;Product=putative glutathione S-transferase(pseudogene);Comments=ML2144A, len:788. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-54 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2561500	2561636	.	-	0	Locus=ML2157A;Name=ML2157A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2157A, len:136. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 6.00E-13 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2561887	2562284	.	-	0	Locus=ML2157B;Name=ML2157B;Function=;Product=hypothetical protein(pseudogene);Comments=ML2157B, len:397. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 9.00E-17 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2562593	2563744	.	+	0	Locus=ML2157C;Name=ML2157C;Function=;Product=hypothetical protein(pseudogene);Comments=ML2157C, len:1151. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-13 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2567654	2568142	.	-	0	Locus=ML2157D;Name=ML2157D;Function=;Product=hypothetical protein(pseudogene);Comments=ML2157D, len:488. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-11 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2582749	2582871	.	-	0	Locus=ML2171A;Name=ML2171A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2171A, len:122. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-09 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2613262	2613357	.	+	0	Locus=ML2199A;Name=ML2199A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2199A, len:95. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-11 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2634278	2634409	.	-	0	Locus=ML2215A;Name=ML2215A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2215A, len:131. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-04 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2642486	2642860	.	+	0	Locus=ML2225A;Name=ML2225A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2225A, len:374. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-12 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2677099	2677260	.	+	0	Locus=ML2253A;Name=ML2253A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2253A, len:161. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-23 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2718274	2718600	.	-	0	Locus=ML2293A;Name=ML2293A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2293A, len:326. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-08 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2726694	2726795	.	+	0	Locus=ML2301A;Name=ML2301A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2301A, len:101. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.002 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2728918	2729076	.	-	0	Locus=ML2304A;Name=ML2304A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2304A, len:86. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-11 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=conserved hypotheticals, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2728984	2729070	.	-	0	Locus=ML2304A;Name=ML2304A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2304A, len:86. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-11 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=conserved hypotheticals, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2740581	2740760	.	-	0	Locus=ML2312A;Name=ML2312A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2312A, len:179. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-09 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2785498	2785699	.	+	0	Locus=ML2344A;Name=ML2344A;Function=;Product=ligC; putative DNA ligase(pseudogene);Comments=ML2344A, len:201. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-17 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2831491	2831851	.	-	0	Locus=ML2364A;Name=ML2364A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2364A, len:360. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-26 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2831918	2832775	.	-	0	Locus=ML2364B;Name=ML2364B;Function=;Product=hypothetical protein(pseudogene);Comments=ML2364B, len:857. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-68 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2832900	2833503	.	+	0	Locus=ML2364C;Name=ML2364C;Function=;Product=hypothetical protein(pseudogene);Comments=ML2364C, len:603. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-39 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2837962	2838309	.	-	0	Locus=ML2369A;Name=ML2369A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2369A, len:1372. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-34 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=unknown, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2837761	2839133	.	-	0	Locus=ML2369A;Name=ML2369A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2369A, len:1372. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-34 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=unknown, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2846233	2846694	.	+	0	Locus=ML2376A;Name=ML2376A;Function=;Product=PPE family protein(pseudogene);Comments=ML2376A, len:461. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 5.00E-11 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2870134	2870534	.	+	0	Locus=ML2398A;Name=ML2398A;Function=;Product=3-ketoacyl-CoA thiolase(pseudogene);Comments=ML2398A, len:400. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 7.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2892403	2892695	.	+	0	Locus=ML2417A;Name=ML2417A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2417A, len:292. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-12 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2899447	2899545	.	+	0	Locus=ML2423A;Name=ML2423A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2423A, len:98. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.90E-02 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2899598	2899834	.	+	0	Locus=ML2423B;Name=ML2423B;Function=;Product=hypothetical protein(pseudogene);Comments=ML2423B, len:236. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2942429	2942992	.	+	0	Locus=ML2468A;Name=ML2468A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2468A, len:563. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2943224	2943508	.	+	0	Locus=ML2468B;Name=ML2468B;Function=;Product=hypothetical protein(pseudogene);Comments=ML2468B, len:284. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-30 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2987612	2987857	.	-	0	Locus=ML2506A;Name=ML2506A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2506A, len:245. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-18 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3001122	3001256	.	-	0	Locus=ML2518A;Name=ML2518A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2518A, len:134. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3006465	3006773	.	-	0	Locus=ML2524A;Name=ML2524A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2524A, len:308. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-06 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3006905	3007521	.	+	0	Locus=ML2524B;Name=ML2524B;Function=;Product=cob(II)yrinic acid a,c-diamide reductase(pseudogene);Comments=ML2524B, len:616. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-58 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3009187	3009255	.	-	0	Locus=ML2526A;Name=ML2526A;Function=;Product=probable trans-aconitate methyltransferase(pseudogene);Comments=ML2526A, len:68. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.006 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3028425	3028858	.	-	0	Locus=ML2541A;Name=ML2541A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2541A, len:433. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 9.00E-29 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3053961	3054491	.	-	0	Locus=ML2561A;Name=ML2561A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2561A, len:530. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-26 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3071597	3071932	.	-	0	Locus=ML2572A;Name=ML2572A;Function=;Product=ilvB_2; acetolactate synthase large subunit(pseudogene);Comments=ML2572A, len:335. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-17 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3072508	3072636	.	-	0	Locus=ML2572B;Name=ML2572B;Function=;Product=hypothetical protein(pseudogene);Comments=ML2572B, len:128. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-10 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3111028	3111171	.	-	0	Locus=ML2606A;Name=ML2606A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2606A, len:143. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-19 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3111488	3111742	.	+	0	Locus=ML2606B;Name=ML2606B;Function=;Product=probable O-methyltransferase(pseudogene);Comments=ML2606B, len:254. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-05 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3133705	3133845	.	+	0	Locus=ML2622A;Name=ML2622A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2622A, len:140. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 4.00E-08 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3138159	3138676	.	+	0	Locus=ML2625A;Name=ML2625A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2625A, len:517. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 7.00E-04 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3141821	3141976	.	+	0	Locus=ML2627A;Name=ML2627A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2627A, len:155. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 8.00E-11 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3142171	3142352	.	+	0	Locus=ML2627B;Name=ML2627B;Function=;Product=hypothetical protein(pseudogene);Comments=ML2627B, len:181. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-07 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3145121	3145198	.	-	0	Locus=ML2629A;Name=ML2629A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2629A, len:77. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 0.006 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3146812	3146994	.	+	0	Locus=ML2630A;Name=ML2630A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2630A, len:528. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-19 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=unknown, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3147153	3147681	.	+	0	Locus=ML2630A;Name=ML2630A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2630A, len:528. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-19 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=unknown, pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3156626	3157309	.	-	0	Locus=ML2638A;Name=ML2638A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2638A, len:683. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-21 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3161876	3162501	.	-	0	Locus=ML2642A;Name=ML2642A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2642A, len:625. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 2.00E-18 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	3193644	3193703	.	+	0	Locus=ML2665A;Name=ML2665A;Function=;Product=hypothetical protein(pseudogene);Comments=ML2665A, len:59. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-03 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1745175	1745290	.	+	0	Locus=ML1450D;Name=ML1450D;Function=;Product=mmpL4_4; probable conserved transmembrane transport protein(pseudogene);Comments=ML1450D (ML1450C), len:406. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 3.00E-28 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2218579	2218980	.	-	0	Locus=ML1830E;Name=ML1830E;Function=;Product=hypothetical protein(pseudogene);Comments=ML1830C, len:401. Possible pseudogene, E-value obtained after tblastn of a functional mycobacterial protein against a database of intergenic Mleprae sequences = 1.00E-09 (See Gomez-Valero et al., 2007);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	977786	978181	.	-	0	Locus=ML0824c;Name=zur;Function=;Product=PROBABLE ZINC UPTAKE REGULATION PROTEIN ZUR;Comments=ML0824c, len: 131 aa. Probable zur, zinc uptake regulation protein. Similar to Rv2359|MTCY27.21c|O05839|Z95208 Mycobacterium tuberculosis zur, zinc uptake regulation protein (130 aa), fasta scores: E(): 0, (86.9% identity in 130 aa), and to FUR_ECOLI|P06975 Escherichia coli ferric uptake regulation protein fur (148 aa), fasta scores: E(): 2.1e-13, 37.2% identity in 129 aa. Belongs to the fur/zur family. Note that previously known as furB.;UniProt_AC=Q9CCG6;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	3249924	3250679	.	+	0	Locus=ML2698;Name=mutT4;Function=;Product=conserved hypothetical protein;Comments=ML2698, len: 251 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 27.1 kda protein Rv3908 TR:O05437 (EMBL:Z94121) fasta scores: E(): 0, 78.6% in 248 aa. Contains Pfam match to entry PF00293 mutT, Bacterial  mutT protein. Contains PS00893 mutT domain signature.;UniProt_AC=Q50195;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1676667	1677056	.	+	0	Locus=ML1396;Name=rplT;Function=;Product=Probable 50S ribosomal protein L20 RplT;Comments=ML1396, len: 129 aa. Probable rplT, 50S ribosomal protein L20. Highly similar to many 50s ribosomal L20 proteins, including: Escherichia coli SW:RL20_ECOLI (P02421) (117 aa), Fasta scores: E(): 1.9e-23, 57.8% identity in 116 aa overlap and Mycobacterium tuberculosis Rv1643 SW:RL20_MYCTU (P94977) (129 aa), Fasta scores: E(): 0, 90.7% identity in 129 aa overlap. Contains Pfam match to entry PF00453 Ribosomal_L20, Ribosomal protein L20. Contains PS00937 Ribosomal protein L20 signature.;UniProt_AC=Q9CC20;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1677111	1677890	.	+	0	Locus=ML1397;Name=tsnR;Function=;Product=Possible 23S rRNA methyltransferase TsnR;Comments=ML1397, len: 259 aa. Possible tsnR, 23S rRNA methyltransferase (EC 2.1.1.-). Similar to several proposed rRNA methylases (SpoU family) e.g. Mycobacterium tuberculosis Rv1644 TR:P94978 (EMBL:Z85982) (260 aa), Fasta scores: E(): 0, 72.8% identity in 257 aa overlap and Escherichia coli SW:TRMH_ECOLI (P19396) (1436 aa), BlastP Expect 7.5. Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family.;UniProt_AC=Q9CC19;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2724186	2724986	.	-	0	Locus=ML2299c;Name=ML2299c;Function=;Product=conserved hypothetical protein;Comments=ML2299c, len: 266 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv3672c or MTV025.020C TR:O69640 (EMBL:AL022121) (273 aa) fasta scores: E(): 0, 76.4% identity in 267 aa. Similar to hypothetical proteins e.g. Streptomyces coelicolor hypothetical protein SCH17.02C TR:Q9XA45 (EMBL:AL079353) (247 aa) fasta scores: E(): 6.7e-26, 43.5% identity in 232 aa. Contains PS01293 Uncharacterized protein family UPF0035 signature.;UniProt_AC=Q9CB94;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2617856	2618977	.	+	0	Locus=ML2203;Name=ML2203;Function=;Product=conserved hypothetical protein;Comments=ML2203, len: 373 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 39.4 kda protein Rv0811c TR:O53825 (EMBL:AL022004) fasta scores: E(): 0, 77.4% id in 367 aa, and to Corynebacterium ammoniagenes orf4 TR:Q9RHX9 (EMBL:AB003158) fasta scores: E(): 1.5e-13, 40.5% identity in 373 aa.;UniProt_AC=Q9CBC4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2878357	2878692	.	-	0	Locus=ML2407c;Name=ML2407c;Function=;Product=POSSIBLE CONSERVED MEMBRANE PROTEIN;Comments=ML2407c, len: 111 aa. Possible conserved membrane protein. Similar to Mycobacterium tuberculosis membrane protein Rv0531 or mtcy25d10.10 TR:O06397 (EMBL:Z95558) (105 aa) fasta scores: E(): 2.4e-24, 73.1% identity in 93 aa. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9CB63;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	158056	159252	.	+	0	Locus=ML0117;Name=ML0117;Function=;Product=Possible aminotransferase;Comments=ML0117, len: 398 aa. Possible aminotransferase (EC 2.6.1.-), highly similar to Rv3778c|P72044|AL123456 possible aminotransferase from M. tuberculosis (398 aa), Fasta scores: E(): 0, (83.4% identity in 398 aa overlap); and similar to many bacterial putative aminotransferases. Also similar to ML0596 and to the C-terminal half of ML0842 from M. leprae.;UniProt_AC=Q9CD97;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	159249	160259	.	-	0	Locus=ML0118c;Name=ML0118c;Function=;Product=Probable oxidireductase;Comments=ML0118c, len: 336 aa. Probable oxidoreductase (EC 1.-.-.-), highly similar to Rv3777|P72043 putative oxidireductase from M. tuberculosis (328 aa). Similar to many oxidoreductases from both bacteria and higher organisms e.g. QOR_MOUSE|P47199 cryZ, quinone oxidoreductase from Mus musculus (331 aa), Fasta scores: E(): 5.5e-21, (31.0% identity in 306 aa overlap). And similar to domains of polyketide synthases ML0135, ML0139, ML1229 and ML2355 from M. leprae. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases.;UniProt_AC=Q9CD96;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	234932	235534	.	+	0	Locus=ML0169;Name=ML0169;Function=;Product=Conserved hypothetical protein;Comments=ML0169, len: 200 aa. Conserved hypothetical protein, highly similar to Rv0966c|Y966_MYCTU|P71544 hypothetical protein from M. tuberculosis (200 aa), Fasta scores: E(): 0, (79.5% identity in 200 aa overlap). Also similar to CAB88834|AL353832 hypothetical protein SCE6.30C from Streptomyces coelicolor (277 aa), Fasta scores: E(): 3.3e-20, (41.0% identity in 205 aa overlap). Previously sequenced as Q9Z5H1|AL035500 (200 aa), Fasta scores: E(): 0, (100.0% identity in 200 aa overlap).;UniProt_AC=Q9Z5H1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	95132	95947	.	+	0	Locus=ML0074;Name=glpQ1;Function=;Product=Probable glycerophosphoryl diester phosphodiesterase GlpQ1 (glycerophosphodiester phosphodiesterase);Comments=ML0074, len: 271 aa. Probable glpQ1, glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46), highly similar to Rv3842c|P96236|AL123456 glpQ1, glycerophosphoryl diester phosphodiesterase from M. tuberculosis (274 aa), Fasta scores: E(): 0, (88.8% identity in 269 aa overlap). Also similar to GLPQ_BACSU|P37965 glpQ, glycerophosphoryl diester phosphodiesterase from Bacillus subtilis (293 aa), Fasta scores: E(): 2.3e-20, (32.0% identity in 250 aa overlap).;UniProt_AC=Q9CDC5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	170662	171351	.	+	0	Locus=ML0127;Name=ML0127;Function=;Product=Possible methyltransferase;Comments=ML0127, len: 229 aa. Possible methyltransferase (EC 2.1.1.-), highly similar to Rv2959c|Q50457|AL123456 Possible methyltransferase from M. tuberculosis (245 aa), Fasta scores: E(): 0, (76.1% identity in 226 aa overlap). Shows weak similarity to O85726|AF073896 cmcI, cephalosporin hydroxylase component of 7 alpha-cephem-methoxylase from Streptomyces clavuligerus (236 aa), Fasta scores: E(): 0.0001, (27.6% identity in 163 aa overlap ); and to other hypothetical proteins.;UniProt_AC=Q9CD89;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2081	3280	.	+	0	Locus=ML0002;Name=dnaN;Function=DNA polymerase III ia a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonucleases activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA [Catalytic activity: N deoxynucleoside triphosphate = N diphosphate + {DNA}N].;Product=Probable DNA polymerase III, [beta] subunit DnaN;Comments=ML0002, len: 399 aa. Probable dnaN, DNA polymerase III (beta chain) (EC 2.7.7.7) (see citations below). Equivalent to other Mycobacterial DNA POLYMERASES III BETA CHAIN e.g. Rv0002|DP3B_MYCTU|Q50790 from M. tuberculosis (402 aa), Fasta scores: E(): 0, (81.9% identity in 403 aa overlap); and DP3B_MYCSM|P52851 from M. smegmatis (397 aa), Fasta scores: E(): 0, (77.3% identity in 397 aa overlap). Previously sequenced as DP3B_MYCLE|P46387 (399 aa), Fasta scores: E(): 0, (100.0% identity in 399 aa overlap). Contains Pfam match to entry PF00712 DNA_pol3_beta, DNA polymerase III beta subunit.;UniProt_AC=P46387;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	3281	4438	.	+	0	Locus=ML0003;Name=recF;Function=;Product=Probable DNA replication and repair protein RecF;Comments=ML0003, len: 385 aa. Probable recF, DNA replication and repair protein (see citations below), highly similar to other Mycobacterial DNA replication and repair proteins e.g. Rv0003|RECF_MYCTU|Q59586 from M. tuberculosis (385 aa), Fasta scores: E(): 0, (76.4% identity in 385 aa overlap); and RECF_MYCSM|P50916 from M. smegmatis (384 aa), Fasta scores: E(): 0, (70.0% identity in 383 aa overlap). Previously sequenced as RECF_MYCLE|P46391 (385 aa), Fasta scores: E(): 0, (99.5% identity in 385 aa overlap). Contains 2 Pfam matches to entry PF00470 RecF, RecF protein. Contains PS00617 RecF protein signature 1. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00618 RecF protein signature 2. Belongs to the RecF family.;UniProt_AC=P46391;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	16566	16979	.	-	0	Locus=ML0012c;Name=ML0012c;Function=;Product=Probable conserved membrane protein;Comments=ML0012c, len: 137 aa. Probable conserved membrane protein, similar to Rv0010c|Y010_MYCTU|P71580 probable conserved membrane protein from M. tuberculosis (141 aa), Fasta scores: E(): 0, (71.5% identity in 137 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDE8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	17134	17415	.	-	0	Locus=ML0013c;Name=ML0013c;Function=;Product=Probable conserved transmembrane protein;Comments=ML0013c, len: 93 aa. Probable conserved transmembrane protein, similar to Rv0011c|Y011_MYCTU|P71581 probable conserved transmembrane protein from M. tuberculosis (93 aa), Fasta scores: E(): 0, (89.2% identity in 93 aa overlap); also similar to Q8NU99 Cgl0040 hypothetical membrane protein from Corynebacterium glutamicum (90 aa), E(): 0, (40.0% identity in 95 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDE7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	100648	102000	.	-	0	Locus=ML0081c;Name=ML0081c;Function=;Product=Probable conserved membrane protein;Comments=ML0081c, len: 450 aa. Probable conserved membrane protein, highly similar to Rv3835c|P96243|AL123456 conserved membrane protein from M. tuberculosis (449 aa), Fasta scores: E(): 0, (69.4% identity in 457 aa overlap). Contains hydrophobic, possible membrane-spanning region near the N-terminus.;UniProt_AC=Q9CDC2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	20879	22192	.	-	0	Locus=ML0017c;Name=pknA;Function=Involved in signal transduction (via phosphorylation). Thought to regulate morphological changes asociated with cell division/differentiation process. Phosphorylates at serine and threonine residues [catalytic activity: ATP + A Protein = ADP + A Phosphoprotein].;Product=Probable transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A);Comments=ML0017c, len: 437 aa. Probable pknA, transmembrane serine/threonine-protein kinase (EC 2.7.1.-), possibly magnesium/manganese dependent (see citations below), highly similar to Rv0015c|PKNA_MYCTU|P71585 pknA, serine/threonine protein kinase from M. tuberculosis (431 aa), Fasta scores: E(): 0, (81.0% identity in 431 aa overlap) and some similarity to Q9ZFS8|AF094711 pksC, serine/threonine protein kinase from Streptomyces coelicolor (556 aa), Fasta scores: E(): 2.1e-29, (39.9% identity in 346 aa overlap). Also similar to ML0016 and ML0897 and to part of ML0304 from M. leprae. Previously sequenced as PKNA_MYCLE|P54743 (437 aa), Fasta scores: E(): 0, (84.6% identity in 448 aa overlap). Contains Pfam match to entry PF00069 pkinase, Eukaryotic protein kinase domain. Contains PS00108 Serine/Threonine protein kinases active-site signature.;UniProt_AC=P54743;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	26584	27051	.	-	0	Locus=ML0021c;Name=ML0021c;Function=;Product=Conserved hypothetical protein;Comments=ML0021c, len: 155 aa. Conserved hypothetical protein, highly similar to Rv0019c|P71589 hypothetical protein from M. tuberculosis (155 aa), fasta scores: E(): 1.8e-59, (90.968% identity in 155 aa overlap); and similar to Q9XA20|AL079308 hypothetical protein SCH69.14 from Streptomyces coelicolor (172 aa), Fasta scores: E(): 2e-21, (44.4% identity in 171 aa overlap). Similar at the C-terminus to ML2076. Previously sequenced as Q50189|Z70722 (155 aa), Fasta scores: E(): 0, (100.0% identity in 155 aa overlap). Contains Pfam match to entry PF00498 FHA, FHA domain.;UniProt_AC=Q50189;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	27173	28639	.	-	0	Locus=ML0022c;Name=ML0022c;Function=;Product=Conserved hypothetical protein;Comments=ML0022c, len: 488 aa. Conserved hypothetical protein (see citations below), highly similar to Rv0020c|P71590|AL123456 hypothetical protein from M. tuberculosis (527 aa), Fasta scores: E(): 0, (71.9% identity in 531 aa overlap); and some similarity at the C-terminus with Q8NU92 Hypothetical protein Cgl0047 from Corynebacterium glutamicum (Brevibacterium flavum) (288 aa), Fasta scores: E(): 0, (55.1% identity in 127 aa overlap). Also similar at the C-terminus to ML2076. Previously sequenced as Q50190|Z70722 (463 aa), Fasta scores: E(): 0, (100.0% identity in 463 aa overlap). Contains Pfam match to entry PF00498 FHA, FHA domain.;UniProt_AC=Q9CDE4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	35287	36123	.	-	0	Locus=ML0031c;Name=ML0031c;Function=;Product=Probable secreted proline rich protein (proline rich 28 kda antigen);Comments=ML0031c, len: 278 aa. Probable secreted proline rich protein (see citations below), similar to Rv0040c|PR28_MYCTU|P71697 secreted proline rich 28 kDa antigen mtc28 from M. tuberculosis (311 aa), Fasta scores: E(): 0, (65.1% identity in 258 aa overlap). Previously sequenced as O33075|Y14967 (278 aa), Fasta scores: E(): 0, (100.0% identity in 278 aa overlap). C-terminal half is similar to a region of ML0246. Contains a probable N-terminal signal sequence.;UniProt_AC=O33075;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	381423	381647	.	-	0	Locus=ML0298c;Name=thiS;Function=;Product=Possible protein ThiS;Comments=ML0298c, len: 74 aa. Possible thiS protein, highly similar to Rv0416|P96262|AL123456 Possible thiS protein from M. tuberculosis (68 aa), Fasta scores: E(): 5.9e-17, (71.6% identity in 74 aa overlap). Shows some similarity to other bacterial thiS proteins e.g. THIS_ECOLI|O32583 thiS, hypothetical protein from Escherichia coli (66 aa), Fasta scores: E(): 0.41, (32.0% identity in 50 aa overlap). Previously sequenced as Q9ZBL3|AL035159 (74 aa), Fasta scores: E(): 1.2e-28, (100.0% identity in 74 aa overlap).;UniProt_AC=Q9ZBL3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	61720	62022	.	-	0	Locus=ML0050c;Name=esxB;Function=;Product=Possible 10 KDA culture filtrate antigen homolog EsxB (lhp) (cfp10);Comments=ML0050c, len: 100 aa. Possible esxB, 10 KDA culture filtrate antigen homolog (see citations below). Similar to Rv3874|O69739|AF004671 esxB, culture filtrate protein 10 kDa CFP-10 from M. tuberculosis (100 aa), Fasta scores: E(): 1.8e-10, (40.0% identity in 100 aa overlap). Also shows weak similarity to others M. tuberculosis proteins e.g. Rv1197|O05299|AL123456 hypothetical protein (98 aa), Fasta scores: E(): 0.061, (21.9% identity in 96 aa overlap), and Rv1038c|P96363|AL123456 hypothetical protein (98 aa), Fasta scores: E(): 0.084, (21.9% identity in 96 aa overlap). These and others form a protein family typically found downstream of a member of the ESAT6 family. Previously sequenced as O33084|Y14967 (100 aa), Fasta scores: E(): 0, (100.0% identity in 100 aa overlap). Belongs to the ESAT6 family.;UniProt_AC=O33084;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	88246	88719	.	-	0	Locus=ML0066c;Name=rraA;Function=;Product=Probable regulator of RNase E activity A RraA;Comments=ML0066c, len: 157 aa. Probable rraA, regulator of RNase E activity A, highly similar to Rv3853|P96224|AL123456 rraA, regulator of RNase E from M. tuberculosis (157 aa), Fasta scores: E(): 0, (87.1% identity in 155 aa overlap). Similar to many others e.g. RRAA_ECOLI|P32165 rraA, Regulator of ribonuclease activity A from Escherichia coli (161 aa), Fasta scores: E(): 2.4e-20, (45.6% identity in 149 aa overlap). Belongs to the rraA family. Previously known as menG.;UniProt_AC=Q9CDD2;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	115371	117302	.	+	0	Locus=ML0093;Name=glfT;Function=;Product=Bifunctional UDP-galactofuranosyl transferase GlfT;Comments=ML0093, len: 643 aa. Probable glfT, bifunctional UDP-galactofuranosyl transferase (EC 2.-.-.-) (see citations below), highly similar to Rv3808c|O53585|AL123456 bifunctional UDP-galactofuranosyl transferase from M. tuberculosis (637 aa), Fasta scores: E(): 0, (85.4% identity in 643 aa overlap).;UniProt_AC=Q9CDB7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	117295	117873	.	+	0	Locus=ML0094;Name=ML0094;Function=;Product=Possible conserved transmembrane protein;Comments=ML0094, len: 192 aa. Possible conserved transmembrane protein, highly similar to Rv3807c|O53584|AL123456) possible transmembrane protein from M. tuberculosis (165 aa), Fasta scores: E(): 0, (72.8% identity in 151 aa overlap); and similar to CAB89062|AL353872 putative integral membrane protein SC5G8.11 from Streptomyces coelicolor (169 aa), Fasta scores: E(): 1.7e-15, (45.1% identity in 153 aa overlap). Also similar to Q8NLQ8 Membrane-associated phospholipid phosphatase from Corynebacterium glutamicum (168 aa), Fasta scores: E(): 1.6e-27, (51.9% identity in 160 aa overlap). Contains hydrophobic, possible membrane-spanning region. Contains Pfam match to entry PF01569 PAP2, PAP2 superfamily.;UniProt_AC=Q9CDB6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	122310	123215	.	+	0	Locus=ML0098;Name=fbpD;Function=Involved in cell wall mycoloylation. Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity.;Product=Secreted MPB51/MPT51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) (85C) ;Comments=ML0098, len: 301 aa. Probable fbpD (alternate gene names: mpt51, mpb51, fbpC1), secreted MPB51/MPT51 antigen protein (fibronectin-binding protein C) (mycolyl transferase 85C) (EC 2.3.1.-) (see citations below), similar to Rv3803c|A85C_MYCTU|P17944 fbpD, secreted MPB51/MPT51 antigen protein from M. tuberculosis fbpC (340 aa), Fasta scores: E(): 0, (40.7% identity in 305 aa overlap). Also similar to the B- and C- proteins of the mycobacterial antigen 85 complexes. Similar to N-terminal region of CSP1_CORGL|Q01377  PS1 protein precursor from Corynebacterium glutamicum csp1 (657 aa), Fasta scores: E(): 1.4e-14, (31.5% identity in 248 aa overlap). Previously sequenced as MPB51 precursor, Q48923|D26486 (299 aa), Fasta scores: E(): 0, (77.5% identity in 302 aa overlap). Also similar to ML0097, ML2028 and ML2655 from M. leprae. Contains probable N-terminal signal sequence. Contains Pfam match to entry PF00756 Esterase, Putative esterase.;UniProt_AC=Q05868;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	147460	149358	.	-	0	Locus=ML0107c;Name=ML0107c;Function=;Product=Probable conserved transmembrane protein;Comments=ML0107c, len: 632 aa. Probable conserved transmembrane protein, highly similar to Rv3792|P72058|AL123456 transmembrane protein from M. tuberculosis (643 aa), Fasta scores: E(): 0, (77.5% identity in 631 aa overlap); and to the C-terminal half of O05765|U46844 membrane protein from Mycobacterium smegmatis ORF3 (603 aa), Fasta scores: E(): 0, (67.8% identity in 267 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDA6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	154576	155394	.	-	0	Locus=ML0114c;Name=rfbE;Function=;Product=Probable lipopolysaccharide-transport ATP-binding protein ABC transporter RfbE;Comments=ML0114c, len: 272 aa. Probable rfbE, polysaccharide-transport ATP-binding protein ABC transporter, involved in O-antigen/lipopolysaccharides (LPS) transport (see first citation below), equivalent to Rv3781|P72047|AL123456 probable rfbE, polysaccharide-transport ATP-binding protein ABC transporter from M. tuberculosis (273 aa), Fasta scores: E(): 0, (91.4% identity in 267 aa overlap). Similar to RFBE_YEREN|Q56903 rfbE, O-antigen export system ATP-binding protein from Yersinia enterocolitica (239 aa), Fasta scores: E(): 0, (46.9% identity in 224 aa overlap); and to other proteins involved in lipopolysaccharide transport. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the ATP-binding transport protein family (ABC transporters).;UniProt_AC=Q9CDA0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	155965	157929	.	-	0	Locus=ML0116c;Name=ML0116c;Function=;Product=Probable conserved transmembrane protein;Comments=ML0116c, len: 654 aa. Probable conserved transmembrane ala-, leu-rich protein, similar to Rv3779|P72045|AL123456 transmembrane protein from M. tuberculosis (666 aa), Fasta scores: E(): 0, (66.5% identity in 666 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CD98;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	167598	168914	.	+	0	Locus=ML0125;Name=ML0125;Function=;Product=Possible glycosyl transferase;Comments=ML0125, len: 438 aa. Possible glycosyl transferase (EC 2.4.1.-) (see citation below), highly similar to M. tuberculosis putative glycosyl transferases e.g. Rv2962c|P95130|AL123456 (449 aa), Fasta scores: E(): 0, (77.5% identity in 426 aa overlap); and Rv2958c|P95134|AL123456 (428 aa), Fasta scores: E(): 0, (74.6% identity in 418 aa overlap). Similar to Q9ZGH7|AF079762 desVII, glycosyl transferase from a macrolide antibiotic biosynthesis gene cluster in Streptomyces venezuelae (426 aa), Fasta scores: E(): 1e-09, (30.0% identity in 237 aa overlap). Shows similarity to bacterial and eukaryotic glycosyl transferases. Also similar to ML0128 and shows weaker similarity to ML0985 from M. leprae.;UniProt_AC=Q9CD91;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	173170	174426	.	-	0	Locus=ML0129c;Name=ML0129c;Function=;Product=Conserved hypothetical protein;Comments=ML0129c, len: 418 aa. Conserved hypothetical protein, highly similar to Rv2953|P95139|AL123456 conserved hypothetical protein from M. tuberculosis (418 aa), Fasta scores: E(): 0, (86.6% identity in 418 aa overlap); and to Rv2449c|O53176|AL123456 conserved hypothetical protein M. tuberculosis (419 aa), Fasta scores: E(): 0, (64.9% identity in 419 aa overlap). Similar to many bacterial hypothetical proteins.;UniProt_AC=Q9CD87;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	174466	175278	.	-	0	Locus=ML0130c;Name=ML0130c;Function=;Product=Probable methyltransferase (Methylase);Comments=ML0130c, len: 270 aa. Probable methyltransferase (EC 2.1.1.-), highly similar to Rv2952|Q50464|AL123456 probable methyltransferase from M. tuberculosis (270 aa), Fasta scores: E(): 0, (83.7% identity in 270 aa overlap); and similar to Q9RMN9 putative methyltransferase from Mycobacterium smegmatis (274 aa), Fasta scores: E(): 0, (50.6% identity in 257 aa overlap). Similar in part to Q54303|X86780 rapM, methyltransferase involved in rapamycin biosynthesis from Streptomyces hygroscopicus (317 aa), Fasta scores: E(): 5e-14, (38.6% identity in 158 aa overlap). Also similar to ML1881c a possible pseudogene similar to M. tuberculosis Rv2952.;UniProt_AC=Q9CD86;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	177170	179212	.	+	0	Locus=ML0132;Name=fadD29;Function=;Product=Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase);Comments=ML0132, len: 680 aa. Probable fadD29, fatty-acid-CoA synthetase (EC 6.2.1.-), similar to various mycobacterial enzymes believed to be involved in polyketide or fatty acid synthesis. Highly similar to Rv2950|P95141|AL123456 fadD29, fatty-acid-CoA synthetase from M. tuberculosis (619 aa), Fasta scores: E(): 0, (80.2% identity in 620 aa overlap); and  similar to P71495|U75685 acyl-CoA synthase from Mycobacterium bovis BCG (582 aa), Fasta scores: E(): 0, (58.5% identity in 585 aa overlap); and to domains of polyketide synthases e.g. Q50857|U24657 safB, saframycin Mx1 synthetase B from Myxococcus xanthus (1770 aa), Fasta scores: E(): 0, (36.2% identity in 589 aa overlap). Also similar to ML0100, ML0138, ML1234 and ML2358 from M. leprae. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme.;UniProt_AC=Q9CD84;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	179256	179888	.	+	0	Locus=ML0133;Name=ML0133;Function=;Product=Conserved hypothetical protein;Comments=ML0133, len: 210 aa. Conserved hypothetical protein, similar to Rv2949c|O86325|AL123456 conserved hypothetical protein from M. tuberculosis (199 aa), Fasta scores: E(): 0, (62.6% identity in 195 aa overlap). Shows weak similarity to O28875|AE001008 hypothetical protein AF1396 from Archaeoglobus fulgidus (162 aa), Fasta scores: E(): 4.2e-05, (26.6% identity in 154 aa overlap). Contains Pfam match to entry PF01947 DUF98, protein of unknown function.;UniProt_AC=Q9CD83;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	182173	188484	.	+	0	Locus=ML0135;Name=pks1;Function=;Product=Probable polyketide synthase Pks1;Comments=ML0135, len: 2103 aa. Probable pks1, polyketide synthase, The N-terminus is highly similar to Rv2947c|P96284|Z83858 pks15, probable polyketide synthase (496 aa), Fasta scores: E(): 0, (90.5% identity in 485 aa overlap); and the remainder is highly similar to Rv2946c|P96285|Z83858 pks1, probable polyketide synthase (1616 aa), Fasta scores: E(): 0, (82.5% identity in 1620 aa overlap). Also similar to many polyketide synthases from M. tuberculosis and other bacteria e.g. AAF71776|AF263912 NysC, nystatin biosynthesis polyketide synthase from Streptomyces noursei (11096 aa), Fasta scores: E(): 0, (50.2% identity in 2161 aa overlap). And similar to ML0101, ML0139, ML1229, ML2353, ML2354, ML2355, ML2356 and ML2357 from M. leprae. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q9CD81;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	194221	200571	.	+	0	Locus=ML0139;Name=mas;Function=;Product=Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas;Comments=ML0139, len: 2116 aa. Probable mas, mycocerosic acid synthase membrane associated, multifunctional enzyme (see citations below), highly similar to many polyketide synthases from M. tuberculosis e.g. Rv2940c|P96291|AL123456) mas, mycocerosic acid synthase (2111 aa), Fasta scores: E(): 0, (88.0% identity in 2119 aa overlap); and to MCAS_MYCBO|Q02251 mas, mycocerosic acid synthase from Mycobacterium bovis (2110 aa), Fasta scores: E(): 0, (85.1% identity in 2122 aa overlap). Also similar to ML0101, ML0135, ML1229, ML2353, ML2354, ML2355, ML2356 and ML2357 from M. leprae. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q9CD78;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	189253	191961	.	-	0	Locus=ML0137c;Name=mmpL7;Function=;Product=Conserved transmembrane transport protein MmpL7;Comments=ML0137c, len: 902 aa. mmpL7, conserved transmembrane transport protein (see citations below), member of RND superfamily, similar to members of the M. tuberculosis mmpL family of membrane proteins e.g. Rv2942|MML7_MYCTU|P96289, mmpL7, conserved transmembrane transport protein (920 aa), Fasta scores: E(): 0, (68.6% identity in 881 aa overlap). Also similar to ML1231 and ML2378 and the pseudogene ML2375 from M. leprae. Contains hydrophobic, possible membrane-spanning regions. Belongs to the MmpL family. In M. tuberculosis it has been experimentaly shown that FadD28 and MmpL7 are transcriptionally coupled.;UniProt_AC=Q7AQN7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	217160	218161	.	-	0	Locus=ML0154c;Name=ML0154c;Function=;Product=Conserved hypothetical protein;Comments=ML0154c, len: 333 aa. Conserved hypothetical protein, highly similar to Rv0950c|P71560|AL123456 conserved hypothetical protein from M. tuberculosis (332 aa), Fasta scores: E(): 0, (71.0% identity in 331 aa overlap). Shows weaker similarity to many bacterial hypothetical proteins which contains a Peptidase family M23/M37 domain. Previously sequenced as Q9Z5H9|AL035500) (343 aa), Fasta scores: E(): 0, (100.0% identity in 333 aa overlap). Contains Pfam match to entry PF01551 Peptidase_M37, Peptidase family M23/M37.;UniProt_AC=Q9CD71;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	265213	265815	.	+	0	Locus=ML0199;Name=ML0199;Function=;Product=Conserved hypothetical protein;Comments=ML0199, len: 200 aa. Conserved hypothetical protein, similar to Rv3647c|O06361|AL123456 hypothetical protein from M. tuberculosis (192 aa), Fasta scores: E(): 0, (80.4% identity in 199 aa overlap). Previously sequenced as O69549|AL023093 (200 aa), Fasta scores: E(): 0, (99.5% identity in 200 aa overlap).;UniProt_AC=O69549;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	214272	216608	.	+	0	Locus=ML0153;Name=uvrD1;Function=;Product=Probable ATP dependent DNA helicase UvrD1;Comments=ML0153, len: 778 aa. Probable uvrD1, ATP dependent DNA helicase (EC 3.6.1.-), highly similar to Rv0949|P71561|AL123456 uvrD1, ATP dependent DNA helicase from M. tuberculosis (771 aa), Fasta scores: E(): 0, (81.4% identity in 780 aa overlap). Similar to many DNA helicases e.g. PCRA_BACST|P56255 pcrA, ATP-dependent helicase from Bacillus stearothermophilus (724 aa), Fasta scores: E(): 0, (43.8% identity in 774 aa overlap). Also similar to ML0637 from M. leprae. Contains Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the UvrD subfamily of helicases. Note that previously known as uvrD.;UniProt_AC=Q9CD72;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	244225	244770	.	+	0	Locus=ML0177;Name=moaB;Function=Thought to be involved in molybdopterin biosynthesis. Catalyzes the dehydratation of 4A-hydroxytetrahydropterins [Catalytic activity: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4A-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O];Product=Possible pterin-4-alpha-carbinolamine dehydratase MoaB2 (4-alpha-hydroxy-tetrahydropterin dehydratase) (pterin-4-A-carbinolamine dehydratase) (phenylalanine hydroxylase-stimulating protein) (PHS) (pterin carbinolamine dehydratase) (PCD);Comments=ML0177, len: 181 aa. Possible moaB2, pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96), highly similar to Rv0984|O53897|AL123456 moaB2, possible pterin-4-alpha-carbinolamine dehydratase from M. tuberculosis (181 aa), Fasta scores: E(): 0, (92.7% identity in 179 aa overlap). Similar to many others e.g. Q9RKA9 Molybdenum cofactor biosynthesis protein from Streptomyces coelicolor A3(2) (179 aa), Fasta scores: E(): 5e-21, (50.0% identity in 150 aa overlap); and to the C-terminal halves of CNX1_ARATH|Q39054 cnx1, multifunctional two-domain protein involved in molybdenum cofactor biosynthesis from Arabidopsis thaliana (670 aa), Fasta scores: E(): 7.7e-10, (36.4% identity in 187 aa overlap); and MOCB_SYNP|Q56208 moaCB, molybdenum cofactor biosynthesis protein from Synechococcus sp. (strain PCC 7942) (319 aa), Fasta scores: E(): 1.3e-09, (35.9% identity in 142 aa overlap). Previously sequenced as Q9Z5G5|AL035500 (181 aa), Fasta scores: E(): 0, (99.4% identity in 181 aa overlap).;UniProt_AC=Q9Z5G5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	244787	245251	.	-	0	Locus=ML0178c;Name=mscL;Function=;Product=Possible large-conductance ion mechanosensitive channel MscL;Comments=ML0178c, len: 154 aa. Possible mscL, large conductance mechanosensitive ion channel (integral membrane protein) (see citations below), highly similar to Rv0985c|MSCL_MYCTU|O53898 mscL, possible mechanosensitive channel protein from M. tuberculosis (151 aa), Fasta scores: E(): 0, (71.0% identity in 155 aa overlap). Similar to many others e.g. MSCL_ECOLI|P23867 mscL, large-conductance mechanosensitive channel from Escherichia coli (136 aa), Fasta scores: E(): 1.3e-07, (32.1% identity in 134 aa overlap). Previously sequenced as MSCL_MYCLE|Q9Z5G4 (154 aa), Fasta scores: E(): 0, (100.0% identity in 154 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF01741 MscL, Large-conductance mechanosensitive channel, MscL. Contains PS01327 Large-conductance mechanosensitive channels mscL family signature. Belongs to the MSCL family.;UniProt_AC=Q9Z5G4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	257035	258567	.	-	0	Locus=ML0192c;Name=ML0192c;Function=;Product=Conserved membrane protein;Comments=ML0192c, len: 510 aa. Conserved membrane protein, highly similar to Rv1002c|O05586|AL123456 conserved membrane protein from M. tuberculosis (503 aa), Fasta scores: E(): 0, (80.4% identity in 510 aa overlap). Also similar to Q9RKD3|AL132674 putative integral membrane protein SCE87.05 from Streptomyces coelicolor (591 aa), Fasta scores: E(): 0, (36.7% identity in 531 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CD61;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	270605	271822	.	+	0	Locus=ML0202;Name=ML0202;Function=;Product=Possible DNA polymerase;Comments=ML0202, len: 405 aa.  Possible DNA polymerase (EC 2.7.7.-), highly similar to Rv3644c|O06363|AL123456 possible DNA polymerase from M. tuberculosis (401 aa), Fasta scores: E(): 0, (84.4% identity in 404 aa overlap). Similar to the N-termini of many DNA polymerase III subunits e.g. HOLB_ECOLI|P28631 holB, DNA polymerase III, delta' subunit from Escherichia coli (334 aa), Fasta scores: E(): 2.9e-13, (35.1% identity in 205 aa overlap); and Q9X906 putative DNA polymerase from Streptomyces coelicolor A3(2) (401 aa). Previously sequenced as O69546|AL023093 (405 aa), Fasta scores: E(): 0, (100.0% identity in 405 aa overlap). Also similar to the N-terminus of ML2335 of M. leprae.;UniProt_AC=O69546;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	266033	268876	.	+	0	Locus=ML0200;Name=topA;Function=;Product=Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-closing enzyme) (topt I);Comments=ML0200, len: 947 aa. Probable topA, DNA topoisomerase I (EC 5.99.1.2) (see citation below), highly similar to Rv3646c|TOP1_MYCTU|Q59567  topA, DNA topoisomerase I from M. tuberculosis (934 aa), Fasta scores: E(): 0, (84.3% identity in 942 aa overlap); and many other e.g. Q9X909|TOP1_STRCO DNA topoisomerase type I from Streptomyces coelicolor (952 aa). Previously sequenced as TOP1_MYCLE|O69548 (947 aa), Fasta scores: E(): 0, (100.0% identity in 947 aa overlap). Contains Pfam match to entry PF01131 Topoisom_bac, Prokaryotic DNA topoisomerase. Contains Pfam match to entry PF01751 Toprim, Toprim domain. Contains PS00396 Prokaryotic DNA topoisomerase I active site. Belongs to the prokaryotic typeI/III topoisomerase family.;UniProt_AC=O69548;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	281543	282031	.	-	0	Locus=ML0210c;Name=ppa;Function=;Product=Probable inorganic pyrophosphatase Ppa (pyrophosphate phospho-hydrolase_ (PPase) (inorganic diphosphatase) (Diphosphate phospho-hydrolase);Comments=ML0210c, len: 162 aa. Probable ppa, inorganic pyrophosphatase (EC 3.6.1.1), highly similar to Rv3628|IPYR_MYCTU|O06379 ppa, inorganic pyrophosphatase from M. tuberculosis (162 aa), Fasta scores: E(): 0, (89.5% identity in 162 aa overlap). Similar to many others e.g. IPYR_SULAC|P50308 ppa, inorganic pyrophosphatase from Sulfolobus acidocaldarius (173 aa), Fasta scores: E(): 1.1e-27, (45.9% identity in 159 aa overlap); and Q9X8I9|IPYR_STRCO inorganic pyrophosphatase from Streptomyces coelicolor A3(2) (163 aa). Previously sequenced as IPYR_MYCLE|O69540 (162 aa), Fasta scores: E(): 0, (99.4% identity in 162 aa overlap). Contains Pfam match to entry PF00719 Pyrophosphatase, Inorganic pyrophosphatase. Contains PS00387 Inorganic pyrophosphatase signature.;UniProt_AC=O69540;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	302835	303659	.	+	0	Locus=ML0232;Name=ML0232;Function=;Product=conserved hypothetical protein;Comments=ML0232, len: 274 aa. Conserved hypothetical protein, highly similar to Rv3600c|O06282|AL123456 conserved hypothetical protein from M. tuberculosis (272 aa), Fasta scores: E(): 0, (90.5% identity in 274 aa overlap). Similar to several other bacterial hypothetical proteins e.g. Q9X8N6|AL049628 hypothetical protein SCE94.31C from Streptomyces coelicolor (265 aa), Fasta scores: E(): 0, (52.0% identity in 269 aa overlap); and other bacterial proteins e.g. Q9F985 putative 32 kDa replication protein from Bacillus stearothermophilus (258 aa).;UniProt_AC=Q9CD56;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	306003	308549	.	+	0	Locus=ML0235;Name=clpC;Function=;Product=Probable ATP-dependent Clp protease ATP-binding subunit ClpC;Comments=ML0235, len: 848 aa. Probable clpC, ATP-dependent clp protease ATP-binding subunit (EC 3.4.-.-), equivalent to Rv3596c|CLPC_MYCTU|O06286 clpC, ATP-dependent clp protease ATP-binding subunit from M. tuberculosis (848 aa), Fasta scores: E(): 0, (97.2% identity in 845 aa overlap). Also highly similar to members of the clpA/clpB family e.g. P37571|CLPC_BACSU clpC, negative regulator of genetic competence (clpC-family) from Bacillus subtilis (810 aa), and HLYB_TREHY|Q54316 tlyB, hemolysin B from Treponema hyodysenteriae (828 aa), Fasta scores: E(): 0, (51.4% identity in 812 aa overlap). Also similar to ML2490 from M. leprae. Contains Pfam match to entry PF00495 clpA_B, Chaperonin clpA/B. Contains Pfam match to entry PF02151 UVR, UvrB/uvrC motif. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the clpA/clpB family, clpC subfamily.;UniProt_AC=P24428;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	316048	316968	.	+	0	Locus=ML0241;Name=ksgA;Function=;Product=Probable dimethyladenosine transferase KsgA (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (16S rRNA dimethylase) (High level kasugamycin resistance protein ksgA) (Kasugamycin dimethyltransferase);Comments=ML0241, len: 306 aa. Probable ksgA, dimethyladenosine transferase (EC 2.1.1.-), highly similar to Rv1010|O05595|AL123456 ksgA, dimethyladenosine transferase from M. tuberculosis (317 aa), Fasta scores: E(): 0, (85.0% identity in 294 aa overlap). Similar to many e.g. KSGA_ECOLI|M68521 ksgA, dimethyladenosine transferase from Escherichia coli (273 aa), Fasta scores: E(): 8.3e-23, (33.7% identity in 261 aa overlap). Contains Pfam match to entry PF00398 RrnaAD, Ribosomal RNA adenine dimethylases. Contains PS01131 Ribosomal RNA adenine dimethylases signature.;UniProt_AC=Q9CD52;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	318220	319854	.	+	0	Locus=ML0243;Name=pks16;Function=;Product=Putative polyketide synthetase Pks16;Comments=ML0243, len: 544 aa. Putative pks16, polyketide synthase, highly similar to Rv1013|O05598|AL123456 putative pks16, polyketide synthases from M. tuberculosis (544 aa), Fasta scores: E(): 0, (82.2% identity in 544 aa overlap); and other M. tuberculosis putative acyl-CoA synthases e.g. fadD33|Rv1345 (521 aa), fadD26|Rv2930 (583 aa). Similar to domains of other polyketide synthases e.g. Q9R9J1|AF184956 mycA, mycosubtilin synthetase from Bacillus subtilis (3971 aa), Fasta scores: E(): 0, (33.7% identity in 404 aa overlap). Also similar to ML0887, ML0100, ML0132, ML0138, ML1051, ML1234, ML1994, ML2358 and ML2546 from M. leprae. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature.;UniProt_AC=Q9CD50;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	323462	324445	.	-	0	Locus=ML0248c;Name=prsA;Function=Catalyzes the formation of PRPP from ATP and ribose 5-phosphate. PRPP is then  used in various biosynthetic  pathways, as for example in the formation of purines, pyrimidines, histidine and tryptophan. [Catalytic activity: ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate];Product=Probable ribose-phosphate pyrophosphokinase PrsA (Phosphoribosyl pyrophosphate synthetase) (PRPP synthetase);Comments=ML0248c, len: 327 aa. Probable prsA, ribose-phosphate pyrophosphokinase (EC 2.7.6.1), equivalent to Rv1017c|P96383|AL123456 prsA, ribose-phosphate pyrophosphokinase from M. tuberculosis (326 aa), Fasta scores: E(): 0, (92.0% identity in 326 aa overlap). Similar to others e.g. SW:KPRS_BACSU|P14193 prs, ribose-phosphate pyrophosphokinase from Bacillus subtilis (317 aa), Fasta scores: E(): 0, (45.8% identity in 323 aa overlap). Contains Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain. Contains PS00103 Purine/pyrimidine phosphoribosyl transferases signature. Belongs to the ribose-phosphate pyrophosphokinase family. Cofactor: both inorganic phosphate and magnesium ion are required for enzymes stability and activity.;UniProt_AC=Q9CD45;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	357557	358777	.	-	0	Locus=ML0275c;Name=metZ;Function=;Product=Probable O-succinylhomoserine sulfhydrylase MetZ (osh sulfhydrylase);Comments=ML0275c, len: 406 aa. Probable metZ, O-succinylhomoserine sulfhydrylase (EC 4.2.99.-), equivalent, but shorter 20 aa in N-terminus to Rv0391|P95199|AL123456 metZ, o-succinylhomoserine sulfhydrylase from M. tuberculosis (406 aa), Fasta scores: E(): 0, (87.9% identity in 406 aa overlap). Similar to many others e.g. METZ_PSEAE|P55218 metZ, o-succinylhomoserine sulfhydrylase from Pseudomonas aeruginosa (403 aa), Fasta scores: E(): 0, (44.3% identity in 406 aa overlap). Previously sequenced as O69592|AL023514 (426 aa), Fasta scores: E(): 0, (100.0% identity in 406 aa overlap). Also similar to ML2394 from M. leprae. Contains Pfam match to entry PF01053 Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme. Belongs to the trans-sulfuration enzymes family. Could also be a cystathionine gamma-synthase (EC 4.2.99.9).;UniProt_AC=Q9CCX4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	368449	369117	.	+	0	Locus=ML0287;Name=ML0287;Function=;Product=Possible conserved transmembrane protein;Comments=ML0287, len: 222 aa. Possible conserved transmembrane protein, highly similar to Rv0364|Y364_MYCTU|O06314 conserved transmembrane protein from M. tuberculosis (227 aa), Fasta scores: E(): 0, (66.1% identity in 227 aa overlap). Similar to many dedA-family proteins e.g. Q9X8J1|AL049841 possible membrane protein SCE9.18C from Streptomyces coelicolor (303 aa), Fasta scores: E(): 0, (42.8% identity in 201 aa overlap). Previously sequenced as O69601|AL023514 (222 aa), Fasta scores: E(): 0, (100.0% identity in 222 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF00597 DedA, DedA family. Belongs to the DedA family.;UniProt_AC=O69601;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	377487	379130	.	+	0	Locus=ML0294;Name=thiC;Function=;Product=Probable thiamine biosynthesis protein ThiC;Comments=ML0294, len: 547 aa. Probable thiC, thiamin biosynthesis protein, equivalent to Rv0423c|THIC_MYCTU|P96269 thiC, thiamine biosynthesis protein from M. tuberculosis (547 aa), Fasta scores: E(): 0, (90.1% identity in 547 aa overlap). Similar to many others e.g. THIC_ECOLI|P30136 thiC, thiamine biosynthesis protein from Escherichia coli (631 aa), Fasta scores: E(): 0, (59.2% identity in 593 aa overlap). Previously sequenced as THIC_MYCLE|Q9ZBL0 (547 aa), Fasta scores: E(): 0, (100.0% identity in 547 aa overlap). Contains Pfam match to entry PF01964 ThiC, ThiC family. Belongs to the ThiC family.;UniProt_AC=Q9ZBL0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	380645	381430	.	-	0	Locus=ML0297c;Name=thiG;Function=;Product=Probable thiamine biosynthesis protein ThiG (Thiazole biosynthesis protein);Comments=ML0297c, len: 261 aa. Probable thiG, thiamine biosynthesis protein, highly similar to Rv0417|P96263|AL123456 thiG, thiamine biosynthesis protein from M. tuberculosis (252 aa), Fasta scores: E(): 0, (86.8% identity in 250 aa overlap). Similar to many proteins involved in the biosynthesis of the thiazole moiety of thiamine e.g. THIG_ECOLI|P30139 thiG, thiamine biosynthetic protein (thiazole moiety) from Escherichia coli (281 aa), Fasta scores: E(): 0, (51.2% identity in 244 aa overlap). Previously sequenced as Q9ZBL2|AL035159 (261 aa), Fasta scores: E(): 0, (99.6% identity in 261 aa overlap). Belongs to the thiG family.;UniProt_AC=Q9ZBL2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	470283	470768	.	+	0	Locus=ML0377;Name=ML0377;Function=;Product=Conserved hypothetical protein;Comments=ML0377, len: 161 aa. Conserved hypothetical protein, highly similar to Rv3422c|YY22_MYCTU|Q50706 conserved hypothetical protein from M. tuberculosis (168 aa), Fasta scores: E(): 0, (77.4% identity in 146 aa overlap). Similar to many other bacterial hypothetical proteins e.g. O86788|YJEE_STRCO|SC6G4.25 from Streptomyces coelicolor (148 aa), Fasta scores: E(): 0, (48.3% identity in 120 aa overlap). Previously sequenced as YY22_MYCLE|Q49864 (161 aa), Fasta scores: E(): 0, (100.0% identity in 161 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q49864;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	904069	904566	.	+	0	Locus=ML0762;Name=ML0762;Function=;Product=Conserved hypothetical protein;Comments=ML0762, len: 165 aa. Conserved hypothetical protein, highly similar to Rv3258c|MTV015.03c|O53351|AL021840 Conserved hypothetical protein from Mycobacterium tuberculosis (163 aa), fasta scores: E(): 0, (76.9% identity in 169 aa overlap), and CAD95378| from M. bovis (163 aa). Similar to other hypothetical proteins e.g. Q9KZL4|AL353862|SCE34.11C hypothetical protein from Streptomyces coelicolor (140 aa), fasta scores: E(): 4.8e-16, (47.0% identity in 151 aa).;UniProt_AC=Q9CCJ8;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	113153	113863	.	-	0	Locus=ML0091c;Name=pirG;Function=;Product=Exported repetitive protein precursor PirG (28 KDa antigen precursor) (cell surface protein);Comments=ML0091c, len: 236 aa. Probable pirG (alternate gene names: P36 or erp for Exported Repeated Protein), cell surface protein precursor (see citations below), similar to Rv3810|ERP_MYCTU|Q50793 pirG, exported repetitive protein precursor from M. tuberculosis   (284 aa), Fasta scores: E(): 1.8e-23, (52.7% identity in 281 aa overlap). Previously sequenced as 28KD_MYCLE|P19361 (236 aa), Fasta scores: E(): 0, (99.6% identity in 236 aa overlap). Contains a probable N-terminal signal sequence.;UniProt_AC=P19361;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	92647	93270	.	-	0	Locus=ML0072c;Name=sodA;Function=;Product=Probable superoxide dismutase SodA;Comments=ML0072c, len: 207 aa. Probable sodA (alternate gene names: sodB, sod), superoxide dismutase (EC 1.15.1.1) (see citations below), highly similar to Rv3846|SODF_MYCTU|P17670 sodA, superoxide dismutase from M. tuberculosis (207 aa), Fasta scores: E(): 0, (80.1% identity in 206 aa overlap); and to many other mycobacterial superoxide dismutases. Previously sequenced as SODM_MYCLE|P13367 (206 aa), Fasta scores: E(): 0, (100.0% identity in 206 aa overlap). Contains Pfam match to entry PF00081 sodfe, Iron/manganese superoxide dismutases (SODM). Contains PS00088 Manganese and iron superoxide dismutases signature. Belongs to the iron/manganese superoxide dismutase family. In M. tuberculosis has been found extracellularly, no signal sequence is present. An alternative secretory pathway may be used.;UniProt_AC=P13367;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	192013	193752	.	-	0	Locus=ML0138c;Name=fadD28;Function=;Product=Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase);Comments=ML0138c, len: 579 aa. Probable fadD28 (alternate gene name: acoas), fatty-acid-CoA synthetase (EC 6.2.1.-) (see citations below), highly similar to several fatty-acyl-CoA synthases from M. tuberculosis e.g. Rv2941|P96290|AL123456 fadD29 (580 aa), Fasta scores: E(): 0, (81.9% identity in 580 aa overlap); and to P71495|U75685 fatty-acyl-CoA synthases from Mycobacterium bovis BCG (582 aa), Fasta scores: E(): 0, (81.4% identity in 580 aa overlap). Similar to the domains of some polyketide synthases e.g. Q50857|U24657 safB, saframycin Mx1 synthetase B from Myxococcus xanthus (1770 aa), Fasta scores: E(): 0, (35.8% identity in 590 aa overlap). And similar to ML0100, ML0132, ML0243, ML1234, ML2358 from M. leprae. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme.;UniProt_AC=Q9CD79;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	353007	354017	.	-	0	Locus=ML0269c;Name=fgd1;Function=;Product=Probable F420-dependent glucose-6-phosphate dehydrogenase Fgd1;Comments=ML0269c, len: 336 aa. Probable fgd1, F420-dependent glucose-6-phosphate dehydrogenase (EC 1.-.-.-), highly similar to others from Mycobacteria e.g. Rv0407|P96253|AL123456 from M. tuberculosis (336 aa), Fasta scores: E(): 0, (89.3% identity in 336 aa overlap); and Q9XC15|AF152394 from Mycobacterium avium (336 aa), Fasta scores: E(): 0, (88.4% identity in 336 aa overlap). And similar to other dehydrogenases e.g. putative dehydrogenase from  Streptomyces coelicolor A3(2) (325 aa). Previously sequenced as O69589|AL023514 (336 aa), Fasta scores: E(): 0, (100.0% identity in 336 aa overlap). Also shows weak similarity to ML0131 from M. leprae. Note that previously known as fgd.;UniProt_AC=O69589;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	85968	86612	.	-	0	Locus=ML0064c;Name=ethR;Function=;Product=Probable transcriptional regulatory repressor protein (TetR-family) EthR;Comments=ML0064c, len: 214 aa. Probable ethR (alternate gene names: aka, etaR), regulatory protein tetR family, involved in ethionamide sensitivity/resistance. Probably negatively controls neighbouring ethA (ML0065, alternate gene names: aka etaA) (see citations below). Highly similar to Rv3855|P96222|Al123456 ethR, regulatory protein tetR family protein from M. tuberculosis (216 aa), Fasta scores: E(): 0, (77.0% identity in 213 aa overlap). Also some similarity to other transcriptional regulators e.g. Q9S1R1 putative tetR-family transcriptional regulator from Streptomyces coelicolor A3 (204 aa), Fasta scores: E(): 0, (29.1% identity in 196 aa overlap). And similar to ML1070 from M. leprae. Contains a probable helix-turn-helix motif at aa 45-66 (Score 1261, SD +3.48) Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family. Belongs to the TetR/AcrR family of transcriptional regulators.;UniProt_AC=Q9CDD3;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	867697	869493	.	-	0	Locus=ML0726c;Name=accA3;Function=INVOLVED IN LONG-CHAIN FATTY ACID SYNTHESIS (AT THE FIRST STEP). CARRIES TWO FUNCTIONS: BIOTIN CARBOXYL CARRIER PROTEIN AND BIOTIN CARBOXYLTRANSFERASE [CATALYTIC ACTIVITY: ATP + BIOTIN-CARBOXYL-CARRIER PROTEIN + CO(2)  = ADP + ORTHOPHOSPHATE + CARBOXYBIOTIN-CARBOXYL-CARRIER PROTEIN].;Product=Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP);Comments=ML0726c, len: 598 aa. Probable accA3, bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain (EC 6.3.4.14), highly similar to P96890|AL123456|Rv3285 Probable accA3, bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain from M. tuberculosis (600 aa), Fasta scores: E(): 0, (88.7% identity in 601 aa overlap). Also highly similar to other proteins e.g. P71122|ACCBC ACYL COENZYME A CARBOXYLASE from Corynebacterium glutamicum (Brevibacterium flavum) (591 aa), FASTA scores: opt: 2776, E(): 8.6e-163, (70.202% identity in 594 aa overlap); Q54119|BCPA2 BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN from Saccharopolyspora erythraea (Streptomyces erythraeus) (591 aa), FASTA scores: E(): 2.1e-139, (69.192% identity in 594 aa overlap). Previously sequenced as BCCA_MYCLE|P46392 (598 aa), Fasta scores: E(): 0, (99.7% identity in 598 aa overlap). Contains Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzymes. Contains Pfam match to entry PF00289 CPSase_L_chain, Carbamoyl-phosphate synthase (CPSase). Contains PS00867 Carbamoyl-phosphate synthase subdomain signature 2. Contains PS00866 Carbamoyl-phosphate synthase subdomain signature 1. Contains PS00188 Biotin-requiring enzymes attachment site. Note previously known as bccA;UniProt_AC=P46392;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	723255	724511	.	+	0	Locus=ML0596;Name=csd;Function=;Product=Probable cysteine desulfurase Csd;Comments=ML0596, len: 418 aa. Probable csd, cysteine desulfurase (EC 4.4.1.- ), highly similar to O53155|AL123456|Rv1464 Probable csd, cysteine desulfurase from M. tuberculosis (417 aa), Fasta scores: E(): 0, (85.4% identity in 417 aa overlap); and CAD96166|Mb1499 from M. bovis (417 aa). Similar to others e.g. Q9XAD5|CSD_STRCO Probable cysteine desulfurase from streptomyces coelicolor (418 aa), fasta scores: E(): 2.5e-88, (53.382% identity in 414 aa overlap). Previously sequenced as Q49690|U00013 (418 aa), Fasta scores: E(): 0, (100.0% identity in 418 aa overlap). And similar to part of ML0842 and to ML0117 and ML1708. Contains Pfam match to entry PF00266 aminotran_5, Aminotransferases class-V. Contains PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. Belongs to the class-V of pyridoxal-phosphate-dependent aminotransferases. Csd subfamily.;UniProt_AC=Q49690;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	654435	656051	.	+	0	Locus=ML0539;Name=PPE;Function=;Product=PPE-family protein;Comments=ML0539, len: 538 aa. Member of the Mycobacteria PPE family, highly similar to P71657|AL123456|Rv1387 PPE20, PPE-family protein from M. tuberculosis (539 aa), Fasta scores: E(): 2.4e-119, (69.5% identity in 544 aa overlap); CAD94283|Mb1422 from M. bovis (539 aa). And similar to ML0411, ML1182, ML1828 and ML1991. Contains Pfam match to entry PF00823 PPE, PPE family.;UniProt_AC=Q9CCQ9;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	161741	162577	.	-	0	Locus=ML0120c;Name=echA1;Function=;Product=Possible enoyl-CoA hydratase EchA21 (enoyl hydrase) (unsaturated acyl-coA hydratase) (crotonase);Comments=ML0120c, len: 278 aa. Possible echA21, enoyl-CoA hydratase (EC 4.2.1.17), highly similar to Rv3774|P75019|AL123456 possible echA21, enoyl-CoA hydratase from M. tuberculosis  (274 aa), Fasta scores: E(): 0, (88.3% identity in 274 aa overlap); and similar to many others e.g. ECH1_RAT|Q62651 ech1, delta3,5-delta2,4-dienoyl-coa isomerase precursor from Rattus norvegicus (327 aa), Fasta scores: E(): 3.5e-31, (38.8% identity in 276 aa overlap). Also shows some similarity to bacterial putative enoyl-CoA hydratases. And similar to ML1241, ML1724, ML2118 and ML2402 from M. leprae. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.;UniProt_AC=Q9CD94;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	136573	139824	.	-	0	Locus=ML0104c;Name=embB;Function=Involved in the biosynthesis of the mycobacterial cell wall arabinan and resistance to ethambutol (Emb; dextro-2,2'-(ethylenediimino)-di-1-butanol). Polymerizes arabinose into the arabinan of arabiogalactan [Catalytic activity: UDP-L-arabinose + indol-3-ylacetyl-myo-inositol = UDP + indol-3-ylacetyl-myo-inositol L-arabinoside].;Product=Probable integral membrane indolylacetylinositol arabinosyltransferase EmbB (arabinosylindolylacetylinositol synthase);Comments=ML0104c, len: 1083 aa. Probable embB, integral membrane protein, indolylacetylinositol arabinosyltransferase (EC 2.4.2.34) (see citations below), highly similar to Rv3795|P72030|AL123456 embB, probable indolylacetylinositol arabinosyltransferase from M. tuberculosis (1098 aa), Fasta scores: E(): 0, (78.0% identity in 1101 aa overlap); and to other putative mycobacterial arabinosyltransferases. Also similar to ML0105 and ML0106 from M. leprae. Involved in resistance to ethambutol in M. tuberculosis. In M. tuberculosis embA is thought to be regulated by embR, but this regulator doesn't exist in M. leprae. Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDA9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	496061	497098	.	-	0	Locus=ML0398c;Name=ML0398c;Function=;Product=Possible D-ribose-binding protein;Comments=ML0398c, len: 345 aa. Possible D-ribose-binding protein, similar to many D-ribose-binding proteins e.g. RBSB_BACSU|P36949 rbsB, D-ribose-binding protein precursor from Bacillus subtilis (305 aa), Fasta scores: E(): 2e-16, (32.6% identity in 273 aa overlap). Previously sequenced as Q49738|U00015) (345 aa), Fasta scores: E(): 0, (100.0% identity in 345 aa overlap). Contains probable N-terminal signal sequence. Contains Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family.;UniProt_AC=Q49738;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	86681	88165	.	+	0	Locus=ML0065;Name=ethA;Function=;Product=Probable monooxygenase EthA;Comments=ML0065, len: 494 aa. Probable ethA (alternate gene names: aka, etaA), monooxygenase required for activation of the pro-drug ethionamide (EC 1.-.-.-) (see citations below), highly similar to other M. tuberculosis monooxygenases e.g. Rv3854c|P96223|AL123456 ethA, monooxygenase (489 aa), Fasta scores: E(): 0, (80.1% identity in 488 aa overlap); and  Rv0892 and Rv1393c. Also similar to the C-terminal half of Q9RZT0|AE001826 putative arylesterase/monoxygenase from Deinococcus radiodurans (833 aa), Fasta scores: E(): 0, (51.5% identity in 480 aa overlap). Shows weaker similarity to O50641|AB010439 steroid monooxygenase from Rhodococcus rhodochrous (549 aa), Fasta scores: E(): 2e-15, (24.9% identity in 469 aa overlap). Also similar to pseudogene ML1732. Contains Pfam match to entry PF00743 FMO-like, Flavin-binding monooxygenase-like.;UniProt_AC=Q7AQN8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	312208	313821	.	-	0	Locus=ML0238c;Name=metS;Function=It is probably essential for cell survival, being required not only for elongation of protein synthesis but also for the initiation of all mRMA translation through initiator tRNA(Fmet) aminoacylation [Catalytic activity: ATP + L-methionine + tRNA(met) = AMP + diphosphate + L-methionyl-tRNA(met)];Product=Probable methionyl-tRNA synthase MetS;Comments=ML0238c, len: 537 aa. Probable metS (MetG), methionyl-tRNA synthetase (EC 6.1.1.10), highly similar to Rv1007c|SYM_MYCTU|O05593 metS, methionyl-tRNA synthetase from M. tuberculosis (519 aa), Fasta scores: E(): 0, (85.7% identity in 516 aa overlap). Similar to several others e.g. SYM_BACST|P23920 metG (metS), methionyl-tRNA synthetase from Bacillus stearothermophilus (649 aa), Fasta scores: E(): 0, (40.9% identity in 550 aa overlap). Contains Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature. Belongs to class-I aminoacyl-tRNA synthetase family. Strong, to cysteinyl-tRNA synthetase.;UniProt_AC=Q9CD55;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	247094	248014	.	+	0	Locus=ML0182;Name=galU;Function=;Product=Probable UTP--glucose-1-phosphate uridylyltransferase GalU (UDP-glucose pyrophosphorylase) (UDPGP) (alpha-D-glucosyls-1-phosphate uridylyltransferase) (uridine diphosphoglucose pyrophosphorylase);Comments=ML0182, len: 306 aa. Probable galU, UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9), highly similar to Rv0993|O05576|AL123456 galU, UTP--glucose-1-phosphate uridylyltransferase from M. tuberculosis (306 aa), Fasta scores: E(): 0, (89.7% identity in 302 aa overlap). Similar to many others e.g. GALU_ECOLI|P25520 galU, UTP--glucose-1-phosphate uridylyltransferase from Escherichia coli (301 aa), Fasta scores: E(): 5.4e-33, (38.8% identity in 299 aa overlap). Previously sequenced as Q9Z5G1|AL035500 (306 aa), Fasta scores: E(): 0, (100.0% identity in 306 aa overlap). Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase. Belongs to the prokaryotic UDPGP family.;UniProt_AC=Q9Z5G1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	82285	83751	.	+	0	Locus=ML0062;Name=gltD;Function=;Product=Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate synthase) (NADH-GOGAT);Comments=ML0062, len: 488 aa. Probable gltD, small subunit of NADH-dependent glutamate synthase (EC 1.4.1.13), highly similar to Rv3858c|P96219|Al123456 gltD, probable NADH-dependent glutamate synthase small subunit from M. tuberculosis  (488 aa), Fasta scores: E(): 0, (87.7% identity in 488 aa overlap); and similar to many other putative glutamate synthase small subunits e.g. GLTD_ECOLI|P09832 gltD, glutamate synthase [NADPH] small chain from Escherichia coli (471 aa), Fasta scores: E(): 0, (37.8% identity in 474 aa overlap). Contains Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase.;UniProt_AC=Q9CDD4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	285584	286225	.	+	0	Locus=ML0214;Name=hpt;Function=;Product=Probable hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (IMP phosphoribosyltransferase) (IMP diphosphorylase) (transphosphoribosyltransferase) (guanine phosphoribosyltransferase);Comments=ML0214, len: 213 aa. Probable hpt (alternate gene name: hprT), hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8), highly similar to other mycobacterial hypoxanthine-guanine phosphoribosyltransferases e.g. Rv3624c|HPRT_MYCTU|O06383 from M. tuberculosis (216 aa), Fasta scores: E(): 0, (83.1% identity in 207 aa overlap); and P96794|HPRT_MYCAV from M. avium (203 aa). And similar to many other bacterial hypoxanthine phosphoribosyltransferases e.g. O33799|AF008931 from Salmonella typhimurium  (178 aa), Fasta scores: E(): 9.6e-32, (50.9% identity in 169 aa overlap). Previously sequenced as O69537|AL023093 (213 aa), Fasta scores: E(): 0, (99.5% identity in 213 aa overlap). Contains Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain. Contains PS00103 Purine/pyrimidine phosphoribosyl transferases signature. Belongs to the purine/pyrimidine phosphoribosyltransferase family;UniProt_AC=O69537;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	36321	39239	.	+	0	Locus=ML0032;Name=leuS;Function=;Product=Probable leucyl-tRNA synthetase LeuS (Leucine--tRNA ligase);Comments=ML0032, len: 972 aa. Probable leuS, leucyl-tRNA synthetase (EC 6.1.1.4), highly similar to Rv0041|SYL_MYCTU|P71698 leuS, leucyl-tRNA synthetase from M. tuberculosis (969 aa), Fasta scores: E(): 0, (83.6% identity in 972 aa overlap) and similar to SYL_BACSU|P36430 leuS, leucyl-tRNA synthetase from Bacillus subtilis (804 aa), Fasta scores: E(): 0, (45.7% identity in 941 aa overlap). Previously sequenced as SYL_MYCLE|Q50192 (972 aa), Fasta scores: E(): 0, (99.9% identity in 972 aa overlap). Contains Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature. Belongs to the class-I aminoacyl-tRNA synthetase family.;UniProt_AC=Q50192;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	25058	26587	.	-	0	Locus=ML0020c;Name=pstP;Function=;Product=Possible serine/threonine phosphatase PstP;Comments=ML0020c, len: 509 aa. Possible pstP, serine/threonine phosphatase (EC 3.1.3.16), highly similar to Rv0018c|P71588|AL123456 ppp, serine/threonine phosphatase from M. tuberculosis (514 aa), Fasta scores: E(): 0, (76.4% identity in 513 aa overlap); and similar to Q9XA19|AL079308 possible protein phosphatase from Streptomyces coelicolor (515 aa), Fasta scores: E(): 0, (40.2% identity in 532 aa overlap). Also similar to many other proteins of undefined function. Previously sequenced as Q50188|Z70722 (509 aa), Fasta scores: E(): 0, (99.6% identity in 509 aa overlap). Contains hydrophobic, possible membrane-spanning region. Proline-rich C-terminus. Previously known as ppp.;UniProt_AC=Q9CDE5;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	175441	176589	.	+	0	Locus=ML0131;Name=ML0131;Function=;Product=Possible oxidoreductase;Comments=ML0131, len: 382 aa. Possible oxidoreductase (EC 1.-.-.-), highly similar to Rv2951c|P95140|AL123456 possible oxidoreductase from M. tuberculosis (381 aa), Fasta scores: E(): 0, (84.8% identity in 382 aa overlap). Similar to O30260|AE001109 conserved hypothetical protein from Archaeoglobus fulgidus AF2411 (363 aa), Fasta scores: E(): 0, (31.5% identity in 362 aa overlap). Shows weak similarity to bacterial oxidoreductases e.g. O68447|AF041061 fgd, F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis (336 aa), Fasta scores: E(): 1.1e-09, (27.7% identity in 292 aa overlap). Shows weak similarity to ML0269 from M. leprae.;UniProt_AC=Q9CD85;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	282157	283542	.	+	0	Locus=ML0211;Name=ML0211;Function=;Product=Possible carboxypeptidase;Comments=ML0211, len: 461 aa. Possible carboxypeptidase, highly similar to Rv3627c|O06380|AL123456 hypothetical ala-rich protein from M. tuberculosis (461 aa), Fasta scores: E(): 0, (76.0% identity in 462 aa overlap). Shows weak similarity to penicillin-binding proteins e.g. O85665|AF071224 pbp3, penicillin binding protein 3 from Neisseria gonorrhoeae (469 aa), Fasta scores: E(): 4.5e-08, (33.1% identity in 163 aa overlap). Also similar to putative carboxypeptidases from Streptomyces coelicolor e.g. Q9X8I8|AL049841 SCE9.15C, possible penicillin-binding protein   (459 aa), Fasta scores: E(): 3.8e-32, (36.3% identity in 435 aa overlap). Previously sequenced as O69539|AL023093 (461 aa), Fasta scores: E(): 0, (99.8% identity in 461 aa overlap). Also similar to ML2215 a possible pseudogene similar to M. tuberculosis Rv3627c. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF02113 Peptidase_S13, D-Ala-D-Ala carboxypeptidase 3 (S13) family.;UniProt_AC=O69539;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	301463	302404	.	+	0	Locus=ML0230;Name=panC;Function=;Product=Probable pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme);Comments=ML0230, len: 313 aa. Probable panC, pantoate--beta-alanine ligase (EC 6.3.2.1), highly similar to Rv3602c|PANC_MYCTU|O06280 panC, pantoate--beta-alanine ligase from M. tuberculosis (309 aa), Fasta scores: E(): 0, (82.2% identity in 297 aa overlap). Similar to many others e.g. PANC_ECOL|P31663 panC, pantoate--beta-alanine ligase from Escherichia coli (283 aa), Fasta scores: E(): 0, (46.1% identity in 269 aa overlap). Previously sequenced as PANC_MYCLE|O69524 (191 aa), Fasta scores: E(): 0, (100.0% identity in 191 aa overlap). Belongs to the pantothenate synthetase family.;UniProt_AC=O69524;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	22189	23667	.	-	0	Locus=ML0018c;Name=pbpA;Function=;Product=Probable penicillin-binding protein PbpA;Comments=ML0018c, len: 492 aa. Probable pbpA, penicillin-binding protein, highly similar to Rv0016c|P71586|AL123456 pbpA, penicillin-binding protein from M. tuberculosis (491 aa), Fasta scores: E(): 0, (85.7% identity in 490 aa overlap). Also similar to PBPC_BACSU|P42971 pbpC, penicillin-binding protein 3 from Bacillus subtilis (668 aa), Fasta scores: E(): 2.8e-15, (24.5% identity in 444 aa overlap). Also similar to region of ML1577. Previously sequenced as Q50185|Z70722 (474 aa), Fasta scores: E(): 0, (96.4% identity in 472 aa overlap). Contains a probable N-terminal signal sequence. Contains Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain.;UniProt_AC=Q9CDE6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	361950	363248	.	-	0	Locus=ML0280c;Name=purA;Function=;Product=Probable adenylosuccinate synthase PurA (IMP--aspartate ligase) (AdSS) (AMPSase);Comments=ML0280c, len: 432 aa. Probable purA, adenylosuccinate synthase (EC 6.3.4.4), highly similar to Rv0357c|PURA_MYCTU|O08381 purA, adenylosuccinate synthase from M. tuberculosis (432 aa), Fasta scores: E(): 0, (87.9% identity in 431 aa overlap). Similar to many others e.g. PURA_ECOLI|P12283 purA, adenylosuccinate synthase from Escherichia coli (431 aa), Fasta scores: E(): 0, (51.1% identity in 425 aa overlap). Previously sequenced as PURA_MYCLE|O69595 (432 aa), Fasta scores: E(): 0, (100.0% identity in 432 aa overlap). Contains Pfam match to entry PF00709 Adenylsucc_synt, Adenylosuccinate synthetase. Contains PS00513 Adenylosuccinate synthetase active site. Contains PS01266 Adenylosuccinate synthetase GTP-binding site. Belongs to the adenylosuccinate synthetase family.;UniProt_AC=O69595;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	23664	25061	.	-	0	Locus=ML0019c;Name=rodA;Function=;Product=Probable cell-division protein RodA;Comments=ML0019c, len: 465 aa. Probable rodA (alternate gene name: ftsW), cell division protein, integral membrane protein, highly similar to Rv0017c|P71587 rodA, cell-division protein from M. tuberculosis (469 aa), Fasta scores: E(): 0, (82.3% identity in 469 aa overlap) and similar to Q9ZBA6|AL109663  ftsW, cell-division protein from Streptomyces coelicolor (456 aa), Fasta scores: E(): 3.3e-25, (32.1% identity in 377 aa overlap). Also similar to ML0913 from m. leprae. Previously sequenced as FTSW_MYCLE|Q50186 (465 aa), Fasta scores: E(): 0, (99.6% identity in 465 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein. Contains PS00428 Cell cycle proteins ftsW/rodA/spoVE signature. Belongs to the FtsW/RodA/SpoVE family.;UniProt_AC=Q50186;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	386630	388933	.	+	0	Locus=ML0304;Name=pknG;Function=Involved in signal transduction (via phosphorylation). Thought to regulate amino-acid uptake and stationary-phase metabolism. Phosphorylates the peptide substrate myelin basic protein (MBP) at serine residues [Catalytic activity: ATP + A protein = ADP + A phosphoprotein].;Product=Probable serine-threonine protein kinase PknG (protein kinase G) (STPK G);Comments=ML0304, len: 767 aa. Probable pknG, serine/threonine-protein kinase (EC 2.7.1.-) (see citations below), highly similar to Rv0410c|P96256|AL123456 pknG, serine/threonine protein kinase from M. tuberculosis (750 aa), Fasta scores: E(): 0, (83.1% identity in 756 aa overlap). Similar to many bacterial putative serine/threonine protein kinases e.g. CAB71204|AL138538 possible protein kinase from Streptomyces coelicolor (903 aa), Fasta scores: E(): 0, (42.0% identity in 793 aa overlap). Similar in part, to protein kinases from Myxococcus xanthus e.g. Q9XBP5|AF159692 pkn12, serine/threonine protein kinase (465 aa), Fasta scores: E(): 2.9e-10, (28.4% identity in 292 aa overlap). Previously sequenced as Q9ZBL8|AL035159) (763 aa), Fasta scores: E(): 0, (100.0% identity in 763 aa overlap). Also similar to regions of ML0016 and ML0017 from M.leprae. Contains Pfam match to entry PF00069 pkinase, Eukaryotic protein kinase domain. Contains PS00108 Serine/Threonine protein kinases active-site signature. Belongs to the Ser/Thr family of protein kinases.;UniProt_AC=P57993;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	397047	397949	.	-	0	Locus=ML0310c;Name=pssA;Function=;Product=Probable CDP-diacylglycerol-serine o-phosphatidyltransferase PssA (Phosphatidylserine synthase) (PS synthase);Comments=ML0310c, len: 300 aa. Probable pssA, PS synthase (CDP-diacylglycerol--serine O-phosphatidyltransferase) (EC 2.7.8.8) (see citation below), integral membrane protein, highly similar to Rv0436c|PSS_MYCTU|P96282 pssA, PS synthase (CDP-diacylglycerol--serine O-phosphatidyltransferase) from M. tuberculosis (286 aa), Fasta scores: E(): 0, (77.9% identity in 285 aa overlap). Similar to many others e.g. PSS_HELPY|Q48269 pssA, CDP-diacylglycerol-serine o-phosphatidyltransferase from Helicobacter pylori (237 aa), Fasta scores: E(): 2.3e-14, (34.6% identity in 234 aa overlap). Previously sequenced as Q9ZBM2|AL035159 (300 aa), Fasta scores: E(): 0, (100.0% identity in 300 aa overlap). Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. Contains PS00379 CDP-alcohol phosphatidyltransferases signature. Belongs to the CDP-alcohol phosphatidyltransferase class-I family.;UniProt_AC=Q9ZBM2;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	411593	412069	.	+	0	Locus=ML0322;Name=ispF;Function=Involved in the terpenoid biosynthesis pathway (at the fifth step). Converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP. Also converts 4-diphosphocytidyl-2C-methyl-D-erythritol into 2C-methyl-D-erythritol 3,4-cyclophosphate and CMP [Catalytic activity: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP].;Product=Probable 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF (MECPS) (MECDP-synthase );Comments=ML0322, len: 158 aa. Probable ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12), highly similar to Rv3581c|YZ81_MYCTU|P96863 probable ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from M. tuberculosis (159 aa), Fasta scores: E(): 0, (79.1% identity in 158 aa overlap). Similar to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthases, e.g. Escherichia coli 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, BAA95145|AB038256 (159 aa), Fasta scores: E(): 1e-17, (41.3% identity in 155 aa overlap). Contains the PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature and Pfam match to entry PF02542 YgbB, putative enzyme of deoxy-xylulose pathway. Belongs to the IspF family.;UniProt_AC=Q9CCW5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	425728	426555	.	-	0	Locus=ML0336c;Name=ML0336c;Function=;Product=Probable conserved ATP-binding protein ABC transporter;Comments=ML0336c, len: 275 aa. Probable conserved ATP-binding protein ABC transporter. Similar to many putative ABC-tranporter ATP-binding proteins e.g. O87477|EMBL:AF077010 troB, ABC transporter ATPase from Chlamydia trachomatis (286 aa), Fasta scores: E(): 4.7e-16, 31.4% identity in 223 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS);UniProt_AC=Q9CCW0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	426564	427472	.	-	0	Locus=ML0337c;Name=ML0337c;Function=;Product=Possible ABC transporter periplasmic binding protein;Comments=ML0337c, len: 302 aa. Possible periplasmic solute-binding protein. Similar but shorter than Rv2059|O07257 Conserved hypothetical protein (511 aa), fasta scores: E(): 2.6e-60 (61.132% identity in 265 aa overlap). Shows weak similarity to periplasmic solute-binding proteins e.g. Q55280|L34630  mntC, periplasmic-binding protein from Synechocystis sp. (strain PCC 6803)  (330 aa), Fasta scores: E(): 0.0001, 26.4% identity in 178 aa overlap.  Contains Pfam match to entry PF01297 Lipoprotein_4, Adhesion lipoprotein. Contains PS50893 ABC_TRANSPORTER_2 ATP-binding cassette and ABC transporter-type domain, PS00017 ATP_GTP_A ATP/GTP-binding site motif A. Belongs to the Periplasmic solute binding protein family.;UniProt_AC=Q9CCV9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	461186	461542	.	-	0	Locus=ML0369c;Name=ML0369c;Function=;Product=Conserved hypothetical protein;Comments=ML0369c, len: 118 aa. Conserved hypothetical unknown protein. Some similarity, in part, to putative oxidoreductase from Streptomyces coelicolor A3(2) (341 aa), Fasta scores: E(): 0, (43.7% identity in 55 aa overlap). Previously sequenced as Q49877|U00020 (118 aa), Fasta scores: E(): 0, (100.0% identity in 118 aa overlap).;UniProt_AC=Q49877;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	456985	457428	.	+	0	Locus=ML0364;Name=rplM;Function=;Product=Probable 50S ribosomal protein L13 RplM;Comments=ML0364, len: 147 aa. Probable rplM, 50S ribosomal protein L13, equivalent to Rv3443c|RL13_MYCTU|O06260 rplM, 50S ribosomal protein L13 from M. tuberculosis (147 aa), Fasta scores: E(): 0, (91.2% identity in 147 aa overlap). Also highly similar to others e.g. Q53874|RL13_STRCO|SC6G4.12 from Streptomyces coelicolor (147 aa). Previuosly sequenced as RL13_MYCLE|P38014 (147 aa), Fasta scores: E(): 0, (99.3% identity in 147 aa overlap). Contains Pfam match to entry PF00572 Ribosomal_L13, Ribosomal protein L13. Contains PS00783 Ribosomal protein L13 signature. Belongs to the L13P family of ribosomal proteins.;UniProt_AC=P38014;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	462980	464857	.	+	0	Locus=ML0371;Name=glmS;Function=;Product=Probable glucosamine-fructose-6-phosphate aminotransferase GlmS (Hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (Glucosamine-6-phosphate synthase);Comments=ML0371, len: 625 aa. Probable glmS, glucosamine--fructose-6-phosphate aminotransferase (EC 2.6.1.16), highly similar to Rv3436c|GLMS_MYCTU|O06253 probable glmS, glucosamine-fructose-6-phosphate aminotransferase from M. tuberculosis (623 aa), Fasta scores: E(): 0, (89.3% identity in 627 aa overlap). Similar to many others e.g. O68956|GLMS_MYCSM from Mycobacterium smegmatis (627 aa), Fasta scores: E(): 0, (84.9% identity in 630 aa overlap); O86781|GLMS_STRCO|SC6G4.18 from Streptomyces coelicolor (614 aa), Fasta scores: E(): 0, (63.3% identity in 626 aa overlap). Also similar to ML0689c a possible pseudogene similar to M. tuberculosis glmS. Previously sequenced as GLMS_MYCLE|P40831 (624 aa), Fasta scores: E(): 0, (99.7% identity in 624 aa overlap). Contains Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II. Contains 2 Pfam matches to entry PF01380 SIS, SIS domain. Belongs to the type-2 gatase domain in the N-terminal section. Belongs to the SIS family, GLMS subfamily, in the C-terminal section. ;UniProt_AC=P40831;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	461946	462815	.	-	0	Locus=ML0370c;Name=ML0370c;Function=;Product=Conserved hypothetical protein;Comments=ML0370c, len: 289 aa. Conserved hypothetical protein, highly similar to Rv3438|O06255|AL123456 conserved hypothetical protein from M. tuberculosis (280 aa), Fasta scores: E(): 0, (80.6% identity in 279 aa overlap). Previously sequenced as Q49872|U00020 (324 aa), Fasta scores: E(): 0, (100.0% identity in 289 aa overlap). Contains PS00107 Protein kinases ATP-binding region signature.;UniProt_AC=Q9CCV6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	473178	473480	.	+	0	Locus=ML0380;Name=groES;Function=;Product=10 kD chaperonin GroES (Protein Cpn10) (groES protein) (BCG-A heat shock protein) (10 kDa antigen);Comments=ML0380, len: 100 aa. groES (alternate gene names: cpn10, mpt57), 10 kDa chaperonin (protein cpn10) (see citations below), equivalent to Rv3418c|CH10_MYCTU|P09621 groES, 10 kD chaperonin from M. tuberculosis (100 aa), Fasta scores: E(): 3.6e-32, (89.9% identity in 99 aa overlap). Also highly similar to others e.g. P15020|CH10_MYCBO|MOPB|GROES from Mycobacterium bovis (99 aa), and P40172|CH10_STRCO|GROES|SC6G4.39 from Streptomyces coelicolor and Streptomyces lividans (102 aa). Previously sequenced as CH10_MYCLE|P24301 (99 aa), Fasta scores: E(): 0, (100.0% identity in 99 aa overlap). Contains Pfam match to entry PF00166 cpn10, Chaperonins 10 Kd subunit. Contains PS00681 Chaperonins cpn10 signature. Belongs to the groES chaperonin family.;UniProt_AC=P24301;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	480662	482251	.	+	0	Locus=ML0387;Name=guaB2;Function=;Product=Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD);Comments=ML0387, len: 529 aa. Probable guaB2, inosine-5'-monophosphate (IMP) dehydrogenase (EC 1.1.1.205), highly similar to Rv3411c|IMDH_MYCTU|Q50715 guaB2, probable inosine-5'-monophosphate dehydrogenase from M. tuberculosis (529 aa), Fasta scores: E(): 0, (92.4% identity in 529 aa overlap). Similar to many others e.g. IMDH_ECOLI|P06981 guaB, inosine-5'-monophosphate dehydrogenase from Escherichia coli (488 aa), Fasta scores: E(): 0, (54.3% identity in 490 aa overlap). Previously sequenced as IMDH_MYCLE|Q49729 (529 aa), Fasta scores: E(): 0, (100.0% identity in 529 aa overlap). Also similar to ML2066 and shows weaker similarity to ML0388 from M. leprae. Contains 2 Pfam matches to entry PF00571 CBS, CBS domain. Contains Pfam match to entry PF00478 IMPDH_C, IMP dehydrogenase / GMP reductase C terminus. Contains Pfam match to entry PF01574 IMPDH_N, IMP dehydrogenase / GMP reductase N terminus. Similar to other eukaryotic and prokaryotic IMPDH and to GMP reductase.;UniProt_AC=Q49729;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	482275	483387	.	+	0	Locus=ML0388;Name=guaB3;Function=;Product=Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogenase) (IMP oxidoreductase) (IMPD) (IMPDH);Comments=ML0388, len: 370 aa. Probable guaB3, inosine-5'-monophosphate (IMP) dehydrogenase (EC 1.1.1.205), equivalent to Rv3410c|YY10_MYCTU|Q50716 guaB3, probable inosine-5'-monophosphate dehydrogenase from M. tuberculosis (375 aa), Fasta scores: E(): 0, (90.5% identity in 368 aa overlap). This ORF is similar in part to ML0387 and ML2066 from M. leprae, which more closely resemble the experimentally characterised IMP-DH's (e.g. from Escherichia coli). This shorter homologue is conserved in several bacterial genera e.g Q9L0I6 putative inosine-5'-monophosphate dehydrogenase from Streptomyces coelicolor A3(2) (374 aa), Fasta scores: E(): 0, (52.2% identity in 368 aa overlap). Previously sequenced as YY10_MYCLE|U00015 (375 aa), Fasta scores: E(): 0, (100.0% identity in 370 aa overlap). Contains Pfam match to entry PF00478 IMPDH_C, IMP dehydrogenase / GMP reductase C terminus. Similar to other eukaryotic and prokaryotic IMPDH and to GMP reductase.;UniProt_AC=Q49721;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	511985	513274	.	-	0	Locus=ML0414c;Name=otsB2;Function=Involved in osmoregulatory trehalose biosynthesis. Mycobacteria can produce trehalose from glucose 6-phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway) [Catalytic activity: trehalose 6-phosphate + H(2)O = trehalose + orthophosphate].;Product=Possible trehalose-6-phosphate phosphatase OtsB2 (Trehalose-phosphatase) (TPP);Comments=ML0414c, len: 429 aa. Possible otsB2, trehalose-6-phosphate phosphatase (EC 3.1.3.12), highly similar to Rv3372|O50401|AL123456 otsB2, trehalose-6-phosphate phosphatase from M. tuberculosis (391 aa), Fasta scores: E(): 0, (67.1% identity in 425 aa overlap). Also weakly similar to several trehalose phosphatases e.g. except at N-terminus, to O64897|AF007779 tppB, trehalose-6-phosphate phosphatase from Arabidopsis thaliana (374 aa), Fasta scores: E(): 2.2e-17, (31.1% identity in 315 aa overlap). Previously sequenced as Q49734|U00015 (429 aa), Fasta scores: E(): 0, (100.0% identity in 429 aa overlap). Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign.;UniProt_AC=Q49734;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	524930	526144	.	+	0	Locus=ML0426;Name=lppS;Function=;Product=Probable conserved lipoprotein LppS;Comments=ML0426, len: 404 aa. Probable lppS, conserved lipoprotein, highly similar to Rv2518c|O53223|AL021185 probable lppS, lipoprotein from M. tuberculosis (408 aa), Fasta scores: E(): 0, (82.6% identity in 403 aa overlap). Does not contain a predicted membrane lipoprotein lipid attachment site (present in lppS), but does contain a possible N-terminal signal sequence. Similar to many predicted lipoproteins from Streptomyces coelicolor e.g. Q9X811|SC6G10.26c putative secreted protein from Streptomyces coelicolor (424 aa). Also similar to ML0569, ML2446 and ML2664 from M. leprae. Previously sequenced as O07707|Z97179 (407 aa), Fasta scores: E(): 0, (100.0% identity in 404 aa overlap).;UniProt_AC=Q9CCU5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	553375	554337	.	-	0	Locus=ML0453c;Name=ML0453c;Function=;Product=Probable acyltransferase;Comments=ML0453c, len: 320 aa. Probable acyltransferase (EC 2.3.1.-), highly similar to Rv2611c|O06203|AL123456 probable acyltransferase from M. tuberculosis (316 aa), Fasta scores: E(): 0, (71.5% identity in 312 aa overlap); and Q9F7Y8 putative acyltransferase from Mycobacterium smegmatis (303 aa), Fasta scores: E(): 0, (67.8% identity in 301 aa overlap). Also similar to other acyltransferases e.g. Q9L283|SCL2.16c putative acyltransferase from Streptomyces coelicolor (311 aa), Fasta scores: E(): 7.4e-48 (48.0% identity in 302 aa overlap); and AAF31766|AF130984 lipid A biosynthesis acyltransferase from Campylobacter jejuni (295 aa), Fasta scores: E(): 0.00017, (20.0% identity in 180 aa overlap). Previously sequenced as O07148|Z96801 (320 aa), Fasta scores: E(): 0, (99.7% identity in 320 aa overlap).;UniProt_AC=O07148;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	550194	551117	.	-	0	Locus=ML0450c;Name=snzP;Function=;Product=Possible pyridoxine biosynthesis protein SnzP;Comments=ML0450c, len: 307 aa. Possible snzP, pyridoxine biosynthesis protein. Highly similar to Rv2606c|YQ06_MYCTU|O06208 snzP, pyridoxine biosynthesis protein from M. tuberculosis (299 aa), Fasta scores: E(): 0, (89.7% identity in 291 aa overlap). Highly conserved in both bacteria and eukaryotes. Highly similar to several pyridoxine biosynthesis proteins and hypothetical proteins e.g. Q9UW83|AF133101 pyroA, pyridoxine biosynthesis protein from Emericella nidulans (304 aa), Fasta scores: E(): 0, (65.9% identity in 299 aa overlap); and SCL2.13c conserved hypothetical protein from Streptomyces coelicolor A3(2) (303 aa). Previously sequenced as YQ06_MYCLE|O07145 (333 aa), Fasta scores: E(): 0, (100.0% identity in 307 aa overlap). Contains Pfam match to entry PF01680, SOR_SNZ family. Contains PS01235 Uncharacterized protein family UPF0019 signature. Belongs to the SOR_SNZ family.;UniProt_AC=O07145;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	576362	577117	.	+	0	Locus=ML0475;Name=ML0475;Function=;Product=Conserved hypothetical protein;Comments=ML0475, len: 251 aa. Conserved hypothetical protein, highly similar to YQ03_MYCTU|O33214|Rv2603c Conserved hypothetical protein from M. tuberculosis (251 aa), Fasta scores: E(): 0, (92.4% identity in 251 aa overlap). Similar to many bacterial hypothetical proteins e.g. Q9L288|SCL2.11c HYPOTHETICAL 26.8 KDA PROTEIN from Streptomyces coelicolor (250 aa), FASTA scores: E(): 2.6e-73, (75.502% identity in 249 aa overlap); and Q9AE12|YFCA HYPOTHETICAL STRUCTURAL PROTEIN from Corynebacterium glutamicum (Brevibacterium flavum) (251 aa), faasta scores: E(): 5.6e-70, (71.315% identity in 251 aa overlap). Previously sequenced as YQ03_MYCLE|Q49645 (251 aa), Fasta scores: E(): 0, (100.0% identity in 251 aa overlap). Contains Pfam match to entry PF01709 DUF28, Domain of unknown function.;UniProt_AC=Q49645;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	667999	668823	.	-	0	Locus=ML0551c;Name=ML0551c;Function=;Product=Putative methyltransferase;Comments=ML0551c, len: 274 aa. Putative methyltransferase, highly similar to YE05_MYCTU|P71673|Rv1405c Putative methyltransferase from M. tuberculosis (274 aa), Fasta scores: E(): 0, (78.0% identity in 273 aa overlap). Shows weak similarity to other methyltransferses e.g. PMTA_RHOSH|Q05197 pmtA, phosphatidylethanolamine N-methyltransferase from Rhodobacter sphaeroides (203 aa), Fasta scores: E(): 7.9e-08, (31.3% identity in 144 aa overlap) and UBIE_ECOLI|P27851 ubiE, ubiquinone/menaquinone biosynthesis methyltransferase from Escherichia coli (251 aa), Fasta scores: E(): 9.1e-06, (28.0% identity in 118 aa overlap).;UniProt_AC=Q9CCQ1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	555663	557771	.	-	0	Locus=ML0456c;Name=thrS;Function=;Product=Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase);Comments=ML0456c, len: 702 aa. Probable thrS, threonyl-tRNA synthetase (Threonine--tRNA ligase) (EC 6.1.1.3), highly similar to Rv2614c|SYT_MYCTU|O06200 thrS, threonyl-tRNA synthetase from M. tuberculosis (692 aa), Fasta scores: E(): 0, (84.0% identity in 702 aa overlap). Similar to many e.g. SYT_THETH|P56881 from Thermus aquaticus (659 aa), Fasta scores: E(): 0, (45.0% identity in 645 aa overlap); P00955|SYT_ECOLI from Escherichia coli (642 aa). Previously sequenced as SYT_MYCLE|O07151 (702 aa), Fasta scores: E(): 0, (100.0% identity in 702 aa overlap). Contains Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II (G, H, P, S and T). Contains PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. Belongs to the class-II aminoacyl-tRNA synthetase family. Cofactor: Binds 1 zinc ion.;UniProt_AC=O07151;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	581788	582399	.	+	0	Locus=ML0482;Name=ruvA;Function=FORMS A COMPLEX WITH RUVB. RUVA STIMULATES, IN THE PRESENCE OF DNA, THE WEAK ATPASE ACTIVITY OF RUVB. THE RUVA-RUVB COMPLEX IN THE PRESENCE OF ATP RENATURES CRUCIFORM STRUCTURE IN SUPERCOILED DNA WITH PALINDROMIC SEQUENCE, INDICATING THAT IT MAY PROMOTE STRAND EXCHANGE REACTIONS IN HOMOLOGOUS RECOMBINATION. RUVAB IS AN HELICASE THAT MEDIATES THE HOLLIDAY JUNCTION MIGRATION BY LOCALIZED DENATURATION AND REANNELING.;Product=Probable Holliday junction DNA helicase component RuvA;Comments=ML0482, len: 203 aa. Probable ruvA, Holliday junction binding protein (see citations below), highly similar to Rv2593c|RUVA_MYCTU|Q50628 ruvA, Holliday junction DNA helicase from M. tuberculosis (196 aa), Fasta scores: E(): 0, (76.4% identity in 203 aa overlap). Also highly similar to others e.g. Q9L290|RUVA from Streptomyces coelicolor (201 aa), FASTA scores:E(): 3.7e-29,(47.500% identity in 200 aa overlap); and Q9AE10|RUVA from Corynebacterium glutamicum (Brevibacterium flavum) (206 aa), fasta scores: E(): 1.6e-26, (44.762% identity in 210 aa overlap). Previously sequenced as RUVA_MYCLE|P40832 (203 aa), Fasta scores: E(): 0, (99.5% identity in 203 aa overlap). Contains Pfam match to entry PF01330 RuvA, Bacterial DNA recombination protein, RuvA. Belongs to the ruvA family.;UniProt_AC=P40832;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	582396	583445	.	+	0	Locus=ML0483;Name=ruvB;Function=FORMS A COMPLEX WITH RUVA. RUVB COULD POSSESS WEAK ATPASE ACTIVITY, WHICH WILL BE STIMULATED BY THE RUVA PROTEIN IN THE PRESENCE OF DNA. THE RUVA-RUVB COMPLEX IN THE PRESENCE OF ATP RENATURES CRUCIFORM STRUCTURE IN SUPERCOILED DNA WITH PALINDROMIC SEQUENCE, INDICATING THAT IT MAY PROMOTE STRAND EXCHANGE REACTIONS IN HOMOLOGOUS RECOMBINATION. RUVAB IS AN HELICASE THAT MEDIATES THE HOLLIDAY JUNCTION MIGRATION BY LOCALIZED DENATURATION AND REANNELING.;Product=Holliday junction binding protein RuvB;Comments=ML0483, len: 349 aa. Probable ruvB, Holliday junction binding protein (EC 3.6.1.-) (see Mizrahi & Andersen 1998), highly similar to Rv2592c|RUVB_MYCTU|Q50629 ruvB, Holliday junction binding protein from M. tuberculosis (344 aa), Fasta scores: E(): 0, (94.4% identity in 342 aa overlap). Also highly similar to others e.g. Q9AE09|RUVB from Corynebacterium glutamicum (Brevibacterium flavum) (363 aa), E(): 7.2e-94, (74.850% identity in 334 aa overlap); and Q9L291|RUVB from Streptomyces coelicolor (357 aa), FASTA scores: E(): 8.1e-86, (66.859% identity in 347 aa overlap). Previously sequenced as RUVB_MYCLE|P40833 (369 aa), Fasta scores: E(): 0, (100.0% identity in 322 aa overlap). Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the ruvB family.;UniProt_AC=P40833;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	591835	593250	.	+	0	Locus=ML0488;Name=secF;Function=;Product=Probable protein-export membrane protein SecF;Comments=ML0488, len: 471 aa. Probable secF, protein-export membrane protein (integral membrane protein) (see citation below), highly similar to SECF_MYCTU|Q50635|Rv2586c secF, putative protein-export membrane protein from M. tuberculosis (442 aa), Fasta scores: E(): 0, (72.1% identity in 456 aa overlap); and CAD94802|Mb2617c from M. bovis (442 aa). Similar to others e.g. Q9AE06|SECF from Corynebacterium glutamicum (Brevibacterium flavum) (403 aa), FASTA scores: E(): 1.8e-67, (46.024% identity in 415 aa overlap); and Q53956|SECF_STRCO|SCL2.05c from Streptomyces coelicolor (373 aa), FASTA scores: E(): 3e-33, (35.941% identity in 409 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Belongs to the secD/secF family, secF family. Part of the prokaryotic protein translocation apparatus which comprises SecA1|ML0799, SecA2|ML2082c, SecD|ML0487, secG|ML0577, SecE|ML1907, SecF|ML0488 and SecY|ML1833.;UniProt_AC=P38386;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2403496	2404458	.	+	0	Locus=ML2011;Name=aao;Function=;Product=PROBABLE D-AMINO ACID OXIDASE AAO;Comments=ML2011, len: 320 aa. Probable aao, D-amino acid oxidase (EC 1.4.3.3). Similar to M. tuberculosis putative D-amino acid oxidase aao Rv1905c TR:O07727 (EMBL:Z97193) (320 aa), Fasta scores: E(): 0, 71.4% identity in 318 aa overlap, and to many others e.g. Bos taurus D-aspartate oxidase SW:OXDD_BOVIN (X95310) (341 aa), Fasta scores: E(): 7e-24, 30.2% identity in 328 aa overlap. Contains Pfam match to entry PF01266 DAO, D-amino acid oxidase.;UniProt_AC=Q9RIA4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	619667	621088	.	+	0	Locus=ML0510;Name=ML0510;Function=;Product=Conserved hypothetical protein;Comments=ML0510, len: 473 aa. Conserved hypothetical protein, highly similar to YP59_MYCT|Q50739|Rv2559c conserved hypothetical ala-, leu-, val-rich protein from M. tuberculosis (452 aa), Fasta scores: E(): 0, (83.4% identity in 452 aa overlap); and CAD94774|Mb2589c from M. bovis (452 aa). Similar to other proteins in bacteria and eukaryotes e.g. Q8NQ21 Uncharacterized ATPase related to the helicase subunit of the Holliday junction resolvase from Corynebacterium glutamicum (Brevibacterium flavum) (459 aa), fasta scores: E(): 1.5e-100, (62.690% identity in 461 aa overlap); and Q9KXP4|SC9C5.30c conserved ATP/GTP binding protein from Streptomyces coelicolor (451 aa), FASTA scores: E(): 3.7e-91, (61.574% identity in 432 aa overlap). Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA). Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CCT1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	631180	631788	.	-	0	Locus=ML0520c;Name=ML0520c;Function=;Product=Probable conserved transmembrane protein;Comments=ML0520c, len: 202 aa. Probable conserved transmembrane protein, highly similar to P95017|AL123456|Rv2536 Possible membrane protein from M. tuberculosis (230 aa), Fasta scores: E(): 2.6e-45, (63.2% identity in 201 aa overlap); and CAD94750|Mb2565 from M. bovis (230 aa). Contains hydrophobic, possible membrane-spanning regions. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CCS2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	633534	634106	.	+	0	Locus=ML0523;Name=nusB;Function=;Product=N utilization substance protein NusB (NusB protein);Comments=ML0523, len: 190 aa. nusB, N utilization substance protein, highly similar but longer to NUSB_MYCTU|P95020|Rv2533c nusB, putative transcription termination protein from M. tuberculosis (156 aa), Fasta scores: E(): 1e-43, (75.7% identity in 148 aa overlap); CAD94747|Mb2562c from M. bovis (156 aa). Also similar to many e.g. P54520|NUSB_BACSU from Bacillus subtilis (131 aa), FASTA scores: E(): 6.3e-15, (41.860% identity in 129 aa overlap); and NUSB_ECOLI|P04381 nusB, N utilization substance protein B from Escherichia coli (139 aa), Fasta scores: E(): 7.4e-08, (38.1% identity in 139 aa overlap). Contains Pfam match to entry PF01029 NusB, NusB family. Belongs to the NusB family.;UniProt_AC=Q9CCR9;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	645582	646547	.	+	0	Locus=ML0532;Name=pyrB;Function=;Product=Probable aspartate carbamoyltransferase PyrB (Aspartate transcarbamylase) (ATCase);Comments=ML0532, len: 321 aa. Probable pyrB, aspartate carbamoyltransferase (EC 2.1.3.2), highly similar to PYRB_MYCTU|P71808|Rv1380 pyrB, aspartate carbamoyltransferase from M. tuberculosis (319 aa), Fasta scores: E(): 0, (89.9% identity in 318 aa overlap); and CAD94276|Mb1415 from M. bovis (319 aa). Similar to many e.g. PYRB_STRCO|Q9KXR2 Aspartate carbamoyltransferase from Streptomyces coelicolor (326 aa), fasta scores: E(): 3.8e-74, (60.559% identity in 322 aa overlap); and PYRB_PSEPU|Q59711 aspartate carbamoyltransferase from Pseudomonas putida (334 aa), Fasta scores: (47.3% identity in 317 aa overlap). And weakly similarity to ML1410. Contains 2 Pfam matches to entry PF00185 OTCace, Aspartate/ornithine carbamoyltransferase. Contains PS00097 Aspartate and ornithine carbamoyltransferases signature. Belongs to the ATCases/OCTases family.;UniProt_AC=Q9CCR5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	678086	678556	.	+	0	Locus=ML0561;Name=ML0561;Function=;Product=Possible conserved membrane protein;Comments=ML0561, len: 156 aa. Possible conserved membrane protein, highly similar to YE17_MYCTU|P71686|Rv1417 Possible conserved membrane protein from M. tuberculosis (154 aa), Fasta scores: E(): 2.4e-43, (75.5% identity in 143 aa overlap); and CAD94313|Mb1452 from M. bovis (154 aa). Similar to other membrane  proteins e.g. Q9RKZ5 Putative membrane protein from Streptomyces coelicolor (156 aa), fasta scores: E(): 2e-05, (27.891% identity in 147 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CCP2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	657267	657899	.	+	0	Locus=ML0541;Name=gmk;Function=;Product=Probable guanylate kinase Gmk (GMP kinase).;Comments=ML0541, len: 210 aa. Probable gmk, guanylate kinase (EC 2.7.4.8), highly similar to KGUA_MYCTU|P71659|Rv1389 gmk, putative guanylate kinase from M. tuberculosis (208 aa), Fasta scores: E(): 1.8e-62, (79.1% identity in 201 aa overlap). Similar to many e.g. Q9KXS0|KGUA_STRCO Guanylate kinase from Streptomyces coelicolor (197 aa), fasta scores: E(): 3e-31, (53.889% identity in 180 aa overlap). Contains Pfam match to entry PF00625 Guanylate_kin, Guanylate kinase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00856 Guanylate kinase signature. Belongs to the Guanylate kinase family.;UniProt_AC=Q9CCQ7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	656896	657213	.	+	0	Locus=ML0540;Name=mihF;Function=;Product=Putative integration host factor MihF;Comments=ML0540, len: 105 aa. Putative mihF, integration host factor, highly similar at the carboxy terminus to P71658|AL123456|Rv1388 mihF, possible integration host factor from M. tuberculosis (190 aa), Fasta scores: E(): 3.8e-35, (98.1% identity in 105 aa overlap) and CAD94284|Mb1423 from M. bovis (190 aa). And highly similar to P96802|U75344 mihF, integration host factor from Mycobacterium smegmatis (105 aa), Fasta scores: E(): 7.5e-32, (94.1% identity in 102 aa overlap).;UniProt_AC=Q9CCQ8;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	652995	653843	.	+	0	Locus=ML0537;Name=pyrF;Function=;Product=Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase);Comments=ML0537, len: 282 aa. Probable pyrF, orotidine 5'-phosphate decarboxylase (EC 4.1.1.23), highly similar to DCOP_MYCTU|P77898|Rv1385 pyrF, orotidine 5'-phosphate decarboxylase from M. tuberculosis (274 aa), Fasta scores: E(): 3e-78, (77.3% identity in 282 aa overlap); and CAD94281|Mb1420 from M. bovis (274 aa). Similar to many e.g. DCOP_MYCSM|O08323 pyrF, orotidine 5'-phosphate decarboxylase from Mycobacterium smegmatis (276 aa), Fasta scores: E(): 2.1e-70, (72.5% identity in 280 aa overlap). Contains Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylases. Contains PS00156 Orotidine 5'-phosphate decarboxylase active site. Belongs to the OMP decarboxylase family.;UniProt_AC=Q9CCR1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	654130	654438	.	+	0	Locus=ML0538;Name=PE4;Function=;Product=PE-family protein;Comments=ML0538, len: 102 aa. Member of the Mycobacteria PE family, highly similar to YD86_MYCTU|P71656|Rv1386 PE15, PE-family protein from M. tuberculosis (102 aa), Fasta scores: E(): 2.8e-25, (72.5% identity in 102 aa overlap); CAD94282|Mb1421 from M. bovis (102 aa). And similar to ML2534, ML1183 ML1053 and ML2129.;UniProt_AC=Q9CCR0;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	674680	675396	.	-	0	Locus=ML0557c;Name=lprG;Function=;Product=Probable conserved lipoprotein LprG;Comments=ML0557c, len: 238 aa. Probable lprG, conserved lipoprotein, highly similar to LPRG_MYCTU|P71679|Rv1411c lprG, putative lipoprotein from M. tuberculosis (234 aa), Fasta scores: E(): 0, (68.1% identity in 238 aa overlap) and similar to other M. tuberculosis lipoproteins e.g. Rv1270c, Rv1368, Rv2945c. Also similar to CAD94307|Mb1446c from M. bovis (236 aa) and to ML0136 from M. leprae. Contains probable N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Note that the Rv1410c-Rv1411c operon seems transcribed from two promoters in Mycobacterium bovis BCG (see Bigi et al., 2000).;UniProt_AC=Q9CCP6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	659722	660933	.	+	0	Locus=ML0544;Name=metK;Function=Involved in the activated Methyl cycle. Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. [CATALYTIC ACTIVITY : ATP + L-METHIONINE + H(2)O = PHOSPHATE + DIPHOSPHATE + S-ADENOSYL-L-METHIONINE];Product=Probable S-adenosylmethionine synthase MetK (MAT) (AdoMet synthetase) (Methionine adenosyltransferase);Comments=ML0544, len: 403 aa. Probable metK, S-adenosylmethionine synthetase (EC 2.5.1.6), highly similar to METK_MYCTU|P77899|Rv1392 metK, putative S-adenosylmethionine synthase from M. tuberculosis (403 aa), Fasta scores: E(): 9.7e-149, (91.3% identity in 403 aa overlap); and CAD94288|Mb1427 from M. bovis (403 aa). Similar to others e.g. METK_STRST|Q9X4Q2 metK, S-adenosylmethionine synthase from Streptomyces spectabilis (411 aa), Fasta scores: E(): 2.3e-115, (73.6% identity in 398 aa overlap). Contains Pfam match to entry PF00438 S-AdoMet_synt, S-adenosylmethionine synthetase. Contains PS00377 S-adenosylmethionine synthetase signature 2. Contains PS00376 S-adenosylmethionine synthetase signature 1. Belongs to the AdoMet synthetase family.;UniProt_AC=Q9CCQ4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	667332	667817	.	+	0	Locus=ML0550;Name=ML0550;Function=;Product=Probable transcriptional regulatory protein (MarR family);Comments=ML0550, len: 161 aa. Probable transcriptional regulatory protein, highly similar to P71672|AL123456|Rv1404 Probable transcriptional regulatory protein from M. tuberculosis (160 aa), Fasta scores: E(): 0, (79.1% identity in 158 aa overlap); and CAD94300|Mb1439 from M. bovis (160 aa). Shows similarity to other regulatory proteins, particular from the marR family e.g. Q9K446 Putative transcriptional regulator from Streptomyces coelicolor (158 aa), fasta scores: E(): 3.7e-25, (54.930% identity in 142 aa overlap). Contains Pfam match to entry PF01047 MarR, MarR family. Belongs to the MarR family of transcriptional regulators.;UniProt_AC=Q9CCQ2;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	671417	672091	.	+	0	Locus=ML0554;Name=rpe;Function=;Product=Probable ribulose-phosphate 3-epimerase Rpe;Comments=ML0554, len: 224 aa. Probable rpe, ribulose-phosphate 3-epimerase (EC 5.1.3.1), highly similar to RPE_MYCTU|P71676|Rv1408 rpe, ribulose-phosphate 3-epimerase from M. tuberculosis (232 aa), Fasta scores: E(): 0, (91.0% identity in 221 aa overlap); and CAD94304|Mb1443 from M. bovis (232 aa). Similar to many e.g. Q9L0Z5|RPE_STRCO Ribulose-phosphate 3-epimerase from Streptomyces coelicolor (228 aa), E(): 3.8e-54, (60.731% identity in 219 aa overlap). Contains Pfam match to entry PF00834 Ribul_P_3_epim, Ribulose-phosphate 3 epimerase family. Contains PS01085 Ribulose-phosphate 3-epimerase family signature 1. Contains PS01086 Ribulose-phosphate 3-epimerase family signature 2. Belongs to the Ribulose-phosphate 3-epimerase family;UniProt_AC=Q9CCP9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	686814	687407	.	+	0	Locus=ML0568;Name=ML0568;Function=;Product=Possible conserved secreted protein;Comments=ML0568, len: 197 aa. Possible secreted protein (see citation below) with a N-terminal signal sequence, similar to O06823|AL123456|Rv1435c Probable conserved Pro-, Gly-, Val-rich secreted protein from M. tuberculosis (202 aa), Fasta scores: E(): 1.7e-07, (38.9% identity in 203 aa overlap); and CAD94331|Mb1470c from M. bovis (209 aa). Pro- and Val-rich protein.;UniProt_AC=Q9CCN7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	675553	676176	.	+	0	Locus=ML0558;Name=ribC;Function=INVOLVED IN RIBOFLAVIN SYNTHESIS. RIBOFLAVIN SYNTHASE IS A BIFUNCTIONAL ENZYME COMPLEX CATALYZING THE FORMATION OF RIBOFLAVIN FROM 5-AMINO-6-(1'-D)- RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE AND L-3,4-DIHYDROHY-2- BUTANONE-4-PHOSPHATE VIA 6,7-DIMETHYL-8-LUMAZINE. THE ALPHA SUBUNIT CATALYZES THE DISMUTATION OF 6,7-DIMETHYL-8-LUMAZINE TO RIBOFLAVIN AND 5-AMINO-6-(1'-D)-RIBITYL-AMINO-2,4(1H,3H)- PYRIMIDINEDIONE.;Product=Probable riboflavin synthase [alpha] chain RibC (RibE);Comments=ML0558, len: 207 aa. Probable ribC (ribE), Riboflavin synthase alpha chain (EC 2.5.1.9), highly similar to RISA_MYCTU|P71680|Rv1412 ribC, riboflavin synthase [alpha] chain from M. tuberculosis (201 aa), Fasta scores: E(): 7.1e-66, (82.4% identity in 199 aa overlap); and CAD94308|Mb1447 from M. bovis (201 aa). Similar to many e.g. RISA_BACSU|P16440 ribE, riboflavin synthase alpha chain from Bacillus subtilis (215 aa), Fasta scores: E(): 9.5e-28, (43.4% identity in 198 aa overlap). Contains 2 Pfam matches to entry PF00677 Lum_binding, Lumazine binding domain. Contains 2 x PS00693 Riboflavin synthase alpha chain family signature.;UniProt_AC=Q9CCP5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	677607	678089	.	+	0	Locus=ML0560;Name=ribH;Function=RIBOFLAVIN SYNTHASE IS A BIFUNCTIONAL ENZYME COMPLEX INVOLVED IN RIBOFLAVIN SYNTHESIS. RIBOFLAVIN SYNTHASE  CATALYZES THE FORMATION OF RIBOFLAVIN FROM 5-AMINO-6-(1'-D)- RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE AND  L-3,4-DIHYDROHY-2- BUTANONE-4-PHOSPHATE VIA 6,7-DIMETHYL-8-LUMAZINE. THE BETA SUBUNIT CATALYZES THE CONDENSATION OF 5-AMINO-6-(1'-D)-RIBITYL- AMINO-2,4(1H,3H)-PYRIMIDINEDIONE WITH L-3,4-DIHYDROHY-2-BUTANONE- 4-PHOSPHATE YIELDING 6,7-DIMETHYL-8-LUMAZINE.;Product=Probable riboflavin synthase beta chain RibH (6,7-dimethyl-8-ribityllumazine synthase) (DMRL synthase) (Lumazine synthase).;Comments=ML0560, len: 160 aa. Probable ribH, riboflavin synthase beta chain (EC 2.5.1.9), highly similar to RISB_MYCTU|P71685|Rv1416 ribH, riboflavin synthase [beta] chain from M. tuberculosis (154 aa), Fasta scores: E(): 0, (78.9% identity in 152 aa overlap); and CAD94312|Mb1451 from M. bovis (154 aa). Similar to many e.g. Q9EWJ9|RISB_STRCO 6,7-dimethyl-8-ribityllumazine synthase from Streptomyces coelicolor (161 aa), fasta scores: E(): 3.8e-30, (54.305% identity in 151 aa overlap). Contains Pfam match to entry PF00885 DMRL_synthase, 6,7-dimethyl-8-ribityllumazine synthase.;UniProt_AC=Q9CCP3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	678871	680814	.	+	0	Locus=ML0562;Name=uvrC;Function=INVOLVED IN NUCLEOTIDE EXCISION REPAIR. THE ABC EXCISION NUCLEASE IS A DNA REPAIR ENZYME THAT CATALYZES THE EXCISION REACTION OF UV-DAMAGED NUCLEOTIDE SEGMENTS PRODUCING OLIGOMERS HAVING THE MODIFIED BASE(S). ATTACHES TO THE UVRA-UVRB COMPLEX, DISPLACING UVRA, AND THE DAMAGED DNA STRAND IS NICKED ON BOTH SIDES OF THE DAMAGED SITE ;Product=Probable excinuclease ABC (subunit C - nuclease) UvrC (UvrC protein) (Excinuclease ABC subunit C);Comments=ML0562, len: 647 aa. Probable uvrC, excinuclease ABC, subunit C (see citations below), highly similar to UVRC_MYCTU|P71689|Rv1420 uvrC, excinuclease ABC subunit C from M. tuberculosis (646 aa), Fasta scores: E(): 0, (87.6% identity in 646 aa overlap); and CAD94316|1455 from M. bovis (646 aa). Similar to many e.g. Q9Z512|UVRC_STRCO UvrABC system protein C (UvrC protein) from Streptomyces coelicolor (728 aa), fasta scores: E(): 1.4e-90, (57.803% identity in 692 aa overlap). Contains Pfam match to entry PF01541 Exci_endo_N, Endo/excinuclease amino terminal domain. Contains Pfam match to entry PF02151 UVR, UvrB/uvrC motif. Contains Pfam match to entry PF00633 HHH, Helix-hairpin-helix motif. Belongs to the UrvC family.;UniProt_AC=Q9CCP1;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	699951	700184	.	+	0	Locus=ML0577;Name=secG;Function=;Product=Probable protein-export membrane protein (Translocase subunit) SecG;Comments=ML0577, len: 77 aa. Probable secG, protein-export membrane protein (translocase subunit) (see citation below), highly similar to SECG_MYCTU|O06819|Rv1440 secG, probable protein-export membrane protein from M. tuberculosis (77 aa), Fasta scores: E(): 1.1e-25, (96.1% identity in 77 aa overlap); and CAD96142|Mb1475 from M. bovis (77 aa). Similar to many e.g. Q9Z521|SECG_STRCO Protein-export membrane protein from Streptomyces coelicolor (102 aa), fasta scores: E(): 3.9e-12, (53.425% identity in 73 aa overlap). Previously sequenced as SECG_MYCLE|P38388 (77 aa), Fasta scores: E(): 3.1e-26, (100.0% identity in 77 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Part of the prokaryotic protein translocation apparatus which comprises SecA1|ML0799, SecA2|ML2082c, SecD|ML0487, secG|ML0577, SecE|ML1907, SecF|ML0488 and SecY|ML1833. ;UniProt_AC=P38388;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	712669	713604	.	-	0	Locus=ML0587c;Name=ML0587c;Function=;Product=Possible unidentified antibiotic-transport integral membrane protein ABC transporter;Comments=ML0587c, len: 311 aa. Possible unidentified antibiotic-transport integral membrane protein ABC transporter (see citation below), highly similar to O53148|AL123456|Rv1456c Possible unidentified antibiotic-transport integral membrane protein ABC transporter from M. tuberculosis (310 aa), Fasta scores: E(): 3.7e-95, (83.3% identity in 300 aa overlap); CAD96158|Mb1491c from M. bovis (310 aa). Similar to other bacterial hypothetical membrane proteins e.g. O87318|AF027770 fxtF, hypothetical protein from Mycobacterium smegmatis (236 aa), Fasta scores: E(): 1.3e-54, (67.5% identity in 228 aa overlap). Previously sequenced as O33142|Z99125 (311 aa), Fasta scores: E(): 0, (99.7% identity in 311 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=O33142;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1331541	1332053	.	+	0	Locus=ML1141;Name=atpF;Function=;Product=PROBABLE ATP SYNTHASE B CHAIN ATPF;Comments=ML1141, len: 170 aa. Probable atpF, ATP synthase B chain (EC 3.6.3.14). Identical to the previously sequenced Mycobacterium leprae ATP synthase B chain (EC 3.6.1.34) SW:ATPF_MYCLE (P45827) (170 aa), Fasta scores: E(): 0, 100.0% identity in 170 aa overlap. Also highly similar to many other proposed ATPase B chain family proteins e.g. Mycobacterium tuberculosis Rv1306 SW:ATPF_MYCTU (Q10596) (171 aa), Fasta scores: E(): 0, 79.5% identity in 171 aa overlap and Bacillus PS3 (Thermophilic bacterium PS-3) SW:ATPF_BACP3 (P09221) (163 aa), Fasta scores: E(): 0.00044, 22.5% identity in 142 aa overlap. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00430 ATP-synt_B, ATP synthase B/B' CF(0).;UniProt_AC=P45827;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	739212	740051	.	+	0	Locus=ML0607;Name=ML0607;Function=;Product=Conserved hypothetical protein;Comments=ML0607, len: 279 aa. Conserved hypothetical protein, highly similar to P71734|AL123456|Rv2409c conserved hypothetical protein from M. tuberculosis (279 aa), Fasta scores: E(): 2e-100, (82.1% identity in 279 aa overlap); and similar to YP69_MYCTU|Q50652|Rv2569c conserved hypothetical protein from M. tuberculosis (314 aa), Fasta scores: E(): 4.1e-13, (33.0% identity in 300 aa overlap). Similar to other bacterial hypothetical proteins e.g. Q9RSX6|AE002037|DR1993 conserved hypothetical protein from Deinococcus radiodurans (274 aa), Fasta scores: E(): 8.2e-25, (33.6% identity in 280 aa overlap). And similar to ML0508 from M. leprae. Previously sequenced as YP69_MYCLE|U00016 (279 aa), Fasta scores: E(): 0, (100.0% identity in 279 aa overlap). Contains Pfam match to entry PF01841 Transglut_core, Transglutaminase-like superfamily.;UniProt_AC=Q49757;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	715976	717757	.	-	0	Locus=ML0591c;Name=ML0591c;Function=;Product=Possible conserved integral membrane protein;Comments=ML0591c, len: 593 aa. Possible conserved integral membrane protein, highly similar to O53150|AL123456|Rv1459c Possible conserved integral membrane protein from M. tuberculosis (591 aa), Fasta scores: E(): 4.6e-90, (78.6% identity in 585 aa overlap); and CAD96161|Mb1494c from M. bovis (591 aa). Similar to other membrane proteins e.g. Q8FNS5 Putative integral membrane protein from Corynebacterium efficiens (521 aa), fasta scores: E(): 1.1e-23, (28.736% identity in 522 aa overlap). And similar to O53508|AL123456|Rv2174 from M. tuberculosis (516 aa) and ML0899 from M. leprae. Previously sequenced as Q49695|U00013 (593 aa), Fasta scores: E(): 0, (100.0% identity in 593 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q49695;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	721295	722473	.	+	0	Locus=ML0594;Name=ML0594;Function=;Product=Conserved hypothetical protein;Comments=ML0594, len: 392 aa. Conserved hypothetical protein, highly similar to YE62_MYCTU|O53153|Rv1462 Conserved hypothetical protein from M. tuberculosis (397 aa), Fasta scores: E(): 1.4e-132, (80.4% identity in 392 aa overlap); and CAD96164|Mb1497 from M. bovis (397 aa). Similar to many bacterial hypothetical proteins e.g. Q9XAD2|AL096839|SCC22.06C conserved hypothetical protein from Streptomyces coelicolor (394 aa), Fasta scores: E(): 2.3e-87, (58.6% identity in 365 aa overlap). Previously sequenced as YE62_MYCLE|Q49682 (392 aa), Fasta scores: E(): 0, (100.0% identity in 392 aa overlap). And similar to the C-terminal half of ML0593. Contains Pfam match to entry PF01458 UPF0051, Uncharacterized protein family (UPF0051).;UniProt_AC=Q49682;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	722470	723252	.	+	0	Locus=ML0595;Name=ML0595;Function=;Product=Probable conserved ATP-binding protein ABC transporter;Comments=ML0595, len: 260 aa. Probable conserved ATP-binding protein ABC transporter, highly similar to O53154|AL123456|Rv1463 conserved ATP-binding protein ABC transporter from M. tuberculosis (266 aa), Fasta scores: E(): 1.7e-81, (85.8% identity in 267 aa overlap); and CAD96165 from M. bovis (266 aa). Similar to many members of the ABC transporter family e.g. Q8NQ77 ABC-type transporter, ATPase component from Corynebacterium glutamicum (Brevibacterium flavum) (252 aa), fasta scores: E(): 3.1e-61, (65.873% identity in 252 aa overlap); and members found in chloroplast genomes e.g. ABCX_CYAPA|P48255 ycf16, probable ATP-dependent transporter from Cyanophora paradoxa (259 aa), Fasta scores: (54.2% identity in 227 aa overlap). Previously sequenced as Q49693|U00013 (260 aa), Fasta scores: E(): 0, (100.0% identity in 260 aa overlap). Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the ATP-binding transport protein family (ABC transporters).;UniProt_AC=Q49693;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	736550	738235	.	+	0	Locus=ML0605;Name=ML0605;Function=;Product=Conserved hypothetical protein;Comments=ML0605, len: 561 aa. Conserved hypothetical protein, highly similar to YO11_MYCTU|P71732|Rv2411c conserved hypothetical protein from M. tuberculosis (551 aa), Fasta scores: E(): 1.4e-187, (87.4% identity in 554 aa overlap); and CAD97295|Mb2434c from M. bovis (551 aa). Similar to other bacterial hypothetical proteins. This CDS and the downstream CDS are also similar to the N- and C-terminal regions respectively, of longer hypothetical proteins from M. tuberculosis and M. leprae e.g. YP67_MYCTU|Q50654|Rv2567 from M. tuberculosis (884 aa), Fasta scores: (32.2% identity in 537 aa overlap); and ML2679 from M. lperae (894 aa). Contains a Gln-rich region at the C-terminus. Previously sequenced as YO11_MYCLE|Q49755 (561 aa), Fasta scores: E(): 0, (100.0% identity in 561 aa overlap).;UniProt_AC=Q49755;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	748383	749429	.	+	0	Locus=ML0615;Name=subI;Function=;Product=Probable sulphate-binding lipoprotein SubI;Comments=ML0615, len: 348 aa. Probable subI, sulfate-binding lipoprotein component of sulfate transport system (see citations below), highly similar to P71744|AL123456|Rv2400c subI, probable sulfate-binding lipoprotein from M. tuberculosis subI (356 aa), Fasta scores: E(): 1.6e-109, (76.5% identity in 340 aa overlap). Similar to many e.g. SUBI_ECOLI|P06997 sbp, sulfate-binding protein precursor from Escherichia coli (329 aa), Fasta scores: E(): 1.2e-28, (35.7% identity in 291 aa overlap). Previously sequenced as Q49748|U00016 (358 aa), Fasta scores: E(): 0, (100.0% identity in 348 aa overlap). Contains Pfam match to entry PF01100 Sulphate_bind, Prokaryotic sulphate- and thiosulphate-binding protein. Belongs to the prokaryotic sulfate binding protein family.;UniProt_AC=Q9CCN3;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	757874	759010	.	+	0	Locus=ML0625;Name=dnaJ2;Function=;Product=Probable chaperone protein DnaJ2;Comments=ML0625, len: 378 aa. Probable dnaJ2, chaperone protein, highly similar to O05825|AL123456|Rv2373c Probable dnaJ2, chaperone protein from M. tuberculosis (382 aa), Fasta scores: E(): 1.7e-138, (88.0% identity in 382 aa overlap); and CAD97255|Mb2394c from M. bovis (382 aa). Similar to many e.g. Q9RDD7|DNJ2_STRCO Chaperone protein dnaJ2 from Streptomyces coelicolor (378 aa), fasta scores: E(): 1.2e-83, (54.068% identity in 381 aa overlap); and DNAJ_ECOLI|P08622 dnaJ, Dna protein from Escherichia coli (375 aa), Fasta scores:  (40.6% identity in 382 aa overlap). Also similar to ML2494. Previously sequenced as Q49762|U00016 (378 aa), Fasta scores: E(): 0, (99.7% identity in 378 aa overlap). Contains Pfam match to entry PF01556 DnaJ_C, DnaJ C terminal region. Contains Pfam match to entry PF00684 DnaJ_CXXCXGXG, DnaJ central domain (4 repeats). Contains Pfam match to entry PF00226 DnaJ, DnaJ domain. Belongs to the DNAJ family.;UniProt_AC=Q49762;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	765912	766718	.	+	0	Locus=ML0633;Name=recO;Function=;Product=Probable DNA repair protein RecO ;Comments=ML0633, len: 268 aa. Probable DNA repair protein recO (Recombination protein O),  highly similar to O05836|AL123456|Rv2362c Probable DNA repair protein recO from M. tuberculosis (265 aa), Fasta scores: E(): 1.1e-98, (86.6% identity in 268 aa overlap); and CAD97244|Mb2383c from M. bovis. Similar to others e.g. Q9L2H3|RECO_STRCO DNA repair protein recO from Streptomyces coelicolor (251 aa), Fasta scores: E(): 9.6e-50, (52.8% identity in 248 aa overlap). Shows weak similarity, except at C-terminus to RECO_BACSU|P42095 recO, DNA repair protein from Bacillus subtilis  (255 aa), Fasta scores: E(): 5.3e-11, (27.3% identity in 176 aa overlap). Previously sequenced as Q49754|U00016 (269 aa), Fasta scores: E(): 0, (100.0% identity in 268 aa overlap). Contain a Pfam match to PF02565; RecO. BELONGS TO THE RECO FAMILY.;UniProt_AC=Q9CCN0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	894550	895476	.	+	0	Locus=ML0752;Name=wbbL;Function=;Product=PROBABLE dTDP-RHA:A-D-GlcNAc-DIPHOSPHORYL POLYPRENOL, A-3-L-RHAMNOSYL TRANSFERASE WbbL1 (ALPHA-L-RHAMNOSE-(1->3)-ALPHA-D-GlcNAc(1->P)-P-DECAPRENYL);Comments=ML0752, len: 308 aa. Probable wbbL1, dTDP-rha:A-D-GlcNAc-diphosphoryl polyprenol A-3-L-rhamnosyl transferase (EC 2.-.-.-) (see citations below), highly similar to Rv3265c|MTCY71.05c|P96870|Z92771 wbbL1, dTDP-RHA:A-D-GLCNAC-DIPHOSPHORYL POLYPRENOL A-3-L-RHAMNOSYL TRANSFERASE from Mycobacterium tuberculosis (301 aa), fasta scores: E(): 3.4e-110, (84.7% identity in 301 aa), and to Q9RN50|AF187550 (see note * below) dTDP-rha:A-D-GlcNAc-diphosphoryl polyprenol from Mycobacterium smegmatis (296 aa), fasta scores: E(): 5.5e-89, (69.9% identity in 296 aa). Contains Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferases. [* Note: UNPUBLISHED (experimental study on Mycobacterium smegmatis). Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases - The cell wall arabinogalactan linker formation enzyme, dTDP-Rha:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase is essential for mycobacterial viability - Mills J.A., Motichka K., Jucker M., Wu H.P., Uhlic B.C., Stern R.J., Scherman M.S., Vissa V.D., Yan W., Pan F., Kimbrel S., Kundu M., McNeil M.].;UniProt_AC=Q9CCK7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	803527	804651	.	+	0	Locus=ML0667;Name=prfB;Function=;Product=Probable peptide chain release factor 2 PrfB (RF-2);Comments=ML0667, len: 374 aa. Probable prfB, peptide chain release factor 2, highly similar to RF2_MYCTU|O05782|Rv3105c prfB, peptide chain release factor 2 from M. tuberculosis (371 aa), Fasta scores: E(): 0, (90.1% identity in 372 aa overlap); and CAD96819|3132c from M. bovis (378 aa). Similar to many e.g. RF2_STRCO|Q53915  prfB, peptide chain release factor 2 from Streptomyces coelicolor (368 aa), Fasta scores: E(): 4.9e-99, (66.9% identity in 369 aa overlap). Also similar to ML1134. Previously sequenced as RF2_MYCLE|O32885 (374 aa), Fasta scores: E(): 0, (99.7% identity in 374 aa overlap). Contains Pfam match to entry PF00472 RF-1, Peptidyl-tRNA hydrolase domain. Contains PS00745 Prokaryotic-type class I peptide chain release factors signature. BELONGS TO THE PROKARYOTIC AND MITOCHONDRIAL RELEASE FACTORS FAMILY.;UniProt_AC=O32885;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	806611	807504	.	+	0	Locus=ML0670;Name=ftsX;Function=INVOLVED IN GROWTH (PRINCIPALLY DURING LOG PHASE CELLS). THOUGHT TO BE INVOLVED IN ACTIVE TRANSPORT OF SEPTATION COMPONENT ACROSS THE MEMBRANE. RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. IS CODED IN AN OPERON ESSENTIAL FOR CELL DIVISION.;Product=Putative cell division protein FtsX (SEPTATION COMPONENT-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER;Comments=ML0670, len: 297 aa. Putative ftsX, cell division protein, septation component transport integral membrane protein ABC transporter, highly similar to FTSX_MYCTU|P96293|Rv3101c Putative ftsX, cell division protein, septation component transport integral membrane protein ABC transporter from M. tuberculosis (297 aa), Fasta scores: E(): 0, (80.8% identity in 297 aa overlap); and CAD96815|Mb3128c from M. bovis (297 aa). Similar to many e.g. FTSX_BACSU|O34876 ftsX, cell division protein ftsX homolog from Bacillus subtilis (296 aa), Fasta scores: E(): 1.5e-14, (25.8% identity in 302 aa overlap). Previously sequenced as FTSX_MYCLE|O32882 (287 aa), Fasta scores: E(): 0, (99.7% identity in 287 aa overlap). Contains hydrophobic, possible membrane-spanning regions. BELONGS TO THE FTSX FAMILY.;UniProt_AC=O32882;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	901764	902903	.	-	0	Locus=ML0759c;Name=fbiA;Function=;Product=Probable F420 biosynthesis protein FbiA;Comments=ML0759c, len: 379 aa. Probable fbiA, F420 biosynthesis protein, equivalent to FBIA F420 biosynthesis protein fbiA from Mycobacterium bovis BCG (see citations below). Highly similar to Rv3261|MTCY71.01|P96866|Z92771 Probable fbiA, F420 biosynthesis protein from Mycobacterium tuberculosis (331 aa), fasta scores: E(): 4.4e-116, (79.0% identity in 333 aa); and to Q9KZK9|AL353862 hypothetical protein from Streptomyces coelicolor (319 aa), fasta scores: E(): 5.8e-65, (52.7% identity in 334 aa). Contains Pfam match to entry PF01933 UPF0052, Uncharacterised protein family.;UniProt_AC=Q9CCK1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	821180	822091	.	-	0	Locus=ML0685c;Name=ML0685c;Function=;Product=Possible hydrolase;Comments=ML0685c, len: 303 aa. Possible hydrolase, highly similar to CAD95491|Mb3370 Conserved hypothetical protein from M. bovis (297 aa), fasta scores: opt: 1343, E(): 1.1e-83, (67.133% identity in 286 aa overlap) and highly similar at the N terminus to O53387|AL123456|Rv3337 conserved hypothetical protein from  M. tuberculosis (82 aa), Fasta scores: E(): 2.8e-17, (74.3% identity in 70 aa overlap) and at the C terminus to O53388|AL123456|Rv3338 conserved hypothetical protein from M. tuberculosis (214 aa), Fasta scores: E(): 0, (65.9% identity in 214 aa overlap). Weakly similar to several hydrolases e.g. BAC74778|Q826V8 Putative hydrolase from Streptomyces avermitilis (307 aa), fasta scores: opt: 286, E(): 1e-11, (29.392% identity in 296 aa overlap). Previously sequenced as Q49926|U00022 (303 aa), Fasta scores: E(): 0, (99.7% identity in 303 aa overlap). Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.;UniProt_AC=Q49926;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	822127	823158	.	+	0	Locus=ML0686;Name=trpS;Function=;Product=Probable tryptophanyl-tRNA synthetase TrpS (TRYPTOPHAN--TRNA LIGASE) (TRPRS) (TRYPTOPHAN TRANSLASE);Comments=ML0686, len: 343 aa. Probable trpS, tryptophanyl-tRNA synthetase (EC 6.1.1.2), highly similar to SYW_MYCTU|O53386|Rv3336c trpS, tryptophanyl-tRNA synthetase from M. tuberculosis (336 aa), Fasta scores: E(): 0, (83.8% identity in 339 aa overlap); and CAD95489|Mb3369c from M. bovis (336 aa). Similar to many e.g. SYW_ECOLI|P00954 trpS, tryptophanyl tRNA synthetase from Escherichia coli (334 aa), Fasta scores: E(): 0, (49.6% identity in 335 aa overlap). Previously sequenced as SYW_MYCLE|Q49901 (343 aa), Fasta scores: E(): 0, (100.0% identity in 343 aa overlap). Contains Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature. BELONGS TO CLASS-I AMINOACYL-TRNA SYNTHETASE FAMILY.;UniProt_AC=Q49901;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	900394	901767	.	-	0	Locus=ML0758c;Name=fbiB;Function=;Product=Probable F420 biosynthesis protein  FbiB;Comments=ML0758c, len: 457 aa. Probable fbiB, F420 biosynthesis protein, equivalent to FBIB F420 biosynthesis protein fbiB from Mycobacterium bovis BCG (see citations below). Highly similar to Rv3262|MTCY71.02|P96867|Z92771 Probable fbiB, F420 biosynthesis protein from Mycobacterium tuberculosis (448 aa), fasta scores: E(): 6.9e-138, (82.2% identity in 445 aa), and to SCE34.18|Q9KZK8|AL353862 putative oxidoreductase from Streptomyces coelicolor (443 aa), fasta scores: E(): 5.4e-65, (50.8% identity in 455 aa); and several hypothetical bacterial proteins. Contains Pfam match to entry PF00881 Nitroreductase, Nitroreductase family. Contains Pfam match to entry PF01996 DUF129, Protein of unknown function.;UniProt_AC=Q9CCK2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2312622	2313215	.	+	0	Locus=ML1929;Name=def;Function=;Product=PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE);Comments=ML1929, len: 197 aa. Probable def, polypeptide deformylase (EC 3.5.1.31). Similar to M. tuberculosis polypeptide deformylase Rv0429c SW:DEF_MYCTU (P96275) (197 aa), Fasta scores: E(): 0, 83.7% identity in 196 aa overlap, and to many others e.g Streptomyces coelicolor polypeptide deformylase SW:DEF_STRCO (Q9XAQ2) (208 aa), Fasta scores: E(): 5.9e-20, 43.8% identity in 176 aa overlap. Contains Pfam match to entry PF01327 Pep_deformylase, Polypeptide deformylase.;UniProt_AC=Q9CBI2;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	833873	834667	.	-	0	Locus=ML0696c;Name=sdhB;Function=;Product=Probable succinate dehydrogenase (iron-sulfur protein subunit) SdhB (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE);Comments=ML0696c, len: 264 aa. Probable sdhB, iron-sulphur protein succinate dehydrogenase SdhB subunit (EC 1.3.99.1), highly similar to O53371|AL123456|Rv3319 sdhB, iron-sulphur protein succinate dehydrogenase from M. tuberculosis (263 aa), Fasta scores: E(): 0, (89.8% identity in 264 aa overlap); and CAD95442| from M. bovis (263 aa). Similar to many e.g. DHSB_ECOLI|P07014 sdhB, succinate dehydrogenase iron-sulfur protein from Escherichia coli  (238 aa), Fasta scores: E(): 0, (42.9% identity in 240 aa overlap). Previously sequenced as Q49916|U00022 (264 aa), Fasta scores: E(): 0, (100.0% identity in 264 aa overlap). Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains. Contains PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. COFACTOR: BINDS THREE DIFFERENT IRON-SULFUR CLUSTERS: A 2FE-2S, A 3FE-4S AND A 4FE-4S. THE IRON-SULFUR CENTERS ARE SIMILAR TO THOSE OF 'PLANT-TYPE' 2FE-2S AND 'BACTERIAL-TYPE' 4FE-4S FERREDOXINS. PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC ANCHOR PROTEIN.;UniProt_AC=Q49916;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	877854	879023	.	+	0	Locus=ML0737;Name=fadE25;Function=;Product=Probable acyl-CoA dehydrogenase FadE25;Comments=ML0737, len: 389 aa. Probable fadE25, Acyl-CoA Dehydrogenase (EC 1.3.99.-), highly similar to Rv3274c|MTCY71.14c|P96879|Z92771 fadE25, Acyl-CoA Dehydrogenase from Mycobacterium tuberculosis (389 aa), fasta scores: E(): 3.5e-155, (92.0% identity in 389 aa). Highly similar to others e.g. Q9RIQ5|AJ250495 fatty acid acyl-CoA dehydrogenase fadE from Streptomyces lividans (385 aa), fasta scores:E(): 3.9e-106, (67.6% identity in 383 aa). Also similar to ML0660, ML0661 and shows weaker similarity to ML2563 from M. leprae. Previously sequenced as ACD_MYCLE|P46703. Contains Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. Contains PS00073 Acyl-CoA dehydrogenases signature 2. Contains PS00072 Acyl-CoA dehydrogenases signature 1. BELONGS TO THE ACYL-COA DEHYDROGENASES FAMILY.;UniProt_AC=P46703;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	851949	853706	.	+	0	Locus=ML0713;Name=glpD;Function=INVOLVED IN AEROBIC RESPIRATION AND OXYDATION OF GLYCEROL. REDUCES AN ACCEPTOR AND GENERATES GLYCERONE PHOSPHATE FROM Sn-GLYCEROL 3-PHOSPHATE. POSSIBLY PLAY A ROLE IN METABOLISM OF RIBOFLAVIN, FAD,FMN [CATALYTIC ACTIVITY: SN-GLYCEROL 3-PHOSPHATE + ACCEPTOR = GLYCERONE PHOSPHATE + REDUCED ACCEPTOR].;Product=Probable glycerol-3-phosphate dehydrogenase GlpD;Comments=ML0713, len: 585 aa. Probable glpd, glycerol-3-phosphate dehydrogenase (EC 1.1.99.5), highly similar to O07168|AL123456|Rv3302c glpD2, glycerol-3-phosphate dehydrogenase from M. tuberculosis (585 aa), Fasta scores: E(): 3e-212, (90.8% identity in 584 aa overlap). Similar to many e.g. GLPD_ECOLI|P13035 glpD, glycerol-3-phosphate dehydrogenase from Escherichia coli (501 aa), Fasta scores: E(): 0, (35.2% identity in 492 aa overlap). Also similar to Q9ZB31|U57100 eriB, erythritol phosphate dehydrogenase from Brucella abortus (502 aa), Fasta scores: E(): 0, (35.4% identity in 483 aa overlap. Previously sequenced as GLPD_MYCLE|P53435 (585 aa), Fasta scores: E(): 0, (99.8% identity in 585 aa overlap). Contains Pfam match to entry PF01224 FAD_Gly3P_dh, FAD-dependent glycerol-3-phosphate dehydrogenase. Contains PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. Contains PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. BELONGS TO THE FAD-DEPENDENT GLYCEROL-3-PHOSPHATE DEHYDROGENASE FAMILY.;UniProt_AC=P53435;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	854777	855691	.	+	0	Locus=ML0715;Name=lpqC;Function=;Product=Possible esterase lipoprotein LpqC;Comments=ML0715, len: 304 aa. Possible lpqC, esterase lipoprotein (EC 3.1.-.-), highly similar to P96903|AL123456|Rv3298c Possible lpqC, esterase lipoprotein from M. tuberculosis (304 aa), Fasta scores: E(): 0, (72.0% identity in 300 aa overlap); and CAD95418|Mb3326c from M. bovis (304 aa). Shows weak similarity to hydrolases e.g. Q9Y871|AF164516 estA, cinnamoyl ester hydrolase from Piromyces equi (536 aa), Fasta scores: E(): 4.8e-12, (27.9% identity in 265 aa overlap) and PHA1_PSELE|P52090 phaZ1, secreted poly(3-hydroxyalkanoate) depolymerase C precursor from Pseudomonas lemoignei (414 aa), Fasta scores: E(): 2.5e-06, (25.6% identity in 320 aa overlap). Previously sequenced as Q49658|U00012 (302 aa), Fasta scores: E(): 0, (99.7% identity in 302 aa overlap). Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CCL5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	873721	874545	.	+	0	Locus=ML0732;Name=birA;Function=BIRA ACTS BOTH AS A BIOTIN-OPERON REPRESSOR AND AS THE ENZYME THAT SYNTHESIZES THE COREPRESSOR, ACETYL-COA:CARBON-DIOXIDE LIGASE. THIS PROTEIN ALSO ACTIVATES BIOTIN TO FORM BIOTINYL-5'-ADENYLATE AND TRANSFERS THE BIOTIN MOIETY TO BIOTIN-ACCEPTING PROTEINS [CATALYTIC ACTIVITY: ATP + BIOTIN + APO-[ACETYL-COA:CARBON-DIOXIDE LIGASE (ADP FORMING)] = AMP + PYROPHOSPHATE + [ACETYL-COA:CARBON-DIOXIDE LIGASE (ADP FORMING)]];Product=POSSIBLE BIFUNCTIONAL PROTEIN BirA: BIOTIN OPERON REPRESSOR + BIOTIN--[ACETYL-COA-CARBOXYLASE] SYNTHETASE (BIOTIN--PROTEIN LIGASE);Comments=ML0732, len: 274 aa. Possible birA, bifunctional protein: biotin operon repressor and biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15), highly similar to P96884|Z92771|Rv3279c|MTCY71.19c birA, bifunctional protein: biotin operon repressor and biotin--[acetyl-CoA-carboxylase] synthetase from Mycobacterium tuberculosis (266 aa), fasta scores: E(): 1.5e-69, (71.2% identity in 271 aa), and CAD95399| from M. bovis (266 aa). Similar to others e.g. P42975|BIRA_BACSU BirA bifunctional protein [Includ  (325 aa), fasta scores: E(): 2.2e-12, (31.321% identity in 265 aa overlap). Lacks the N-terminal helix-turn-helix domain, so may not act as a repressor. Contains Pfam match to entry PF01317 BPL, Biotin protein ligase.;UniProt_AC=Q9CCL3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	918369	920138	.	+	0	Locus=ML0775;Name=lpqB;Function=;Product=probable conserved lipoprotein LpqB;Comments=ML0775, len: 589 aa.  Probable lpqB, conserved lipoprotein, highly similar to Rv3244c|MTCY20B11.19c|O05889|Z95121 lpqB, conserved lipoprotein from Mycobacterium tuberculosis (583 aa), fasta scores: E(): 3.2e-198, (87.9% identity in 579 aa); and CAD95364| from M. bovis (583 aa). Similar to other putative lipoproteins e.g. Q9KYX0|AL355774|SCE33.13C putative lipoprotein from  Streptomyces coelicolor (615 aa), fasta scores: E(): 0.00039, (24.4% identity in 624 aa). Contains a probable N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CCJ0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1155160	1155675	.	+	0	Locus=ML0988;Name=recX;Function=;Product=PROBABLE REGULATORY PROTEIN RECX;Comments=ML0988, len: 171 aa. Probable recX, regulatory protein. Identical to the previously sequenced Mycobacterium leprae putative regulatory protein RecX, though to interact with RecA SW:RECX_MYCLE (P37859) (171 aa), Fasta scores: E(): 0, 100.0% identity in 171 aa overlap. Also highly similar to RecX from Mycobacterium tuberculosis Rv2736c SW:RECX_MYCTU (O33280) (174 aa), Fasta scores: E(): 0, 77.0% identity in 174 aa overlap and several others. Note the overlap with upstream recA.;UniProt_AC=P37859;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	877244	877759	.	+	0	Locus=ML0736;Name=purE;Function=INVOLVED IN PURINE BIOSYNTHESIS (SIXTH STEP). THIS SUBUNIT CAN ALONE TRANSFORM AIR TO CAIR, BUT IN ASSOCIATION WITH PURK, WHICH POSSESSES AN ATPASE ACTIVITY, AN ENZYME COMPLEX IS PRODUCED WHICH IS CAPABLE OF CONVERTING AIR TO CAIR EFFICIENTLY UNDER PHYSIOLOGICAL CONDITION [CATALYTIC ACTIVITY: 1-(5-PHOSPHORIBOSYL)-5-AMINO-4-IMIDAZOLE-CARBOXYLATE = 1-(5-PHOSPHORIBOSYL)-5-AMINOIMIDAZOLE + CO(2)].;Product=Probable phosphoribosylaminoimidazole carboxylase catalytic subunit PurE (AIR CARBOXYLASE) (AIRC);Comments=ML0736, len: 171 aa. Probable purE, phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21), highly similar to Rv3275c|MTCY71.15c|PUR6_MYCTU|P96880 purE, phosphoribosylaminoimidazole carboxylase catalytic subunit from Mycobacterium tuberculosis (174 aa), fasta scores: E(): 2.9e-49, (81.5% identity in 168 aa) and CAD95395| from M. bovis (174 aa). Similar to several e.g. PUR6_CORAM|Q44679 phosphoribosylaminoimidazole carboxylase catalytic subunit from  Corynebacterium ammoniagenes (177 aa),  fasta scores: E(): 1.1e-33, (66.2% identity in 148 aa). Previously sequenced as PUR6_MYCLE|P46702. Contains Pfam match to entry PF00731 AIRC, AIR carboxylase.;UniProt_AC=P46702;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	875925	877244	.	+	0	Locus=ML0735;Name=purK;Function=INVOLVED IN PURINE BIOSYNTHESIS (SIXTH STEP). POSSESSES AN ATPASE ACTIVITY THAT IS DEPENDENT ON THE PRESENCE OF AIR (AMINOIMIDAZOLE RIBONUCLEOTIDE). THE ASSOCIATION OF PURK AND PURE PRODUCES AN ENZYME COMPLEX CAPABLE OF CONVERTING AIR TO CAIR EFFICIENTLY UNDER PHYSIOLOGICAL CONDITION [CATALYTIC ACTIVITY: 1-(5-PHOSPHORIBOSYL)-5-AMINO-4-IMIDAZOLE-CARBOXYLATE = 1-(5-PHOSPHORIBOSYL)-5-AMINOIMIDAZOLE + CO(2)];Product=Probable phosphoribosylaminoimidazole carboxylase ATPase subunit PurK (AIR CARBOXYLASE) (AIRC);Comments=ML0735, len: 439 aa. Probable purK, phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21), highly similar to Rv3276c|MTCY71.16c|PURK_MYCTU purK, phosphoribosylaminoimidazole carboxylase ATPase subunit from Mycobacterium tuberculosis (429 aa), fasta scores: E(): 0, (76.1% identity in 444 aa). Similar to several e.g. PURK_CORAM|Q44678 phosphoribosylaminoimidazole carboxylase ATPase subunit purK  from Corynebacterium ammoniagenes (413 aa), fasta scores: E(): 9.9e-64, (48.3% identity in 404 aa). Previously sequenced as PURK_MYCLE|P46701. Contains Pfam match to entry PF02222 ATP-grasp, ATP-grasp domain.;UniProt_AC=P46701;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	903526	904029	.	-	0	Locus=ML0761c;Name=ML0761c;Function=;Product=conserved hypothetical protein;Comments=ML0761c, len: 167 aa. Conserved hypothetical protein, highly similar but longer than Rv3259|MTV015.04|O53352|AL021840 Conserved hypothetical protein from Mycobacterium tuberculosis (139 aa), fasta scores: E(): 6.9e-56, (89.2% identity in 139 aa); and CAD95379| from M. bovis (139 aa). Also similar to Q9S425|AF164439 hypothetical 6.0 kDa protein (partial CDS) from Mycobacterium smegmatis (54 aa), fasta scores: E(): 1e-10, (75.5% identity in 53 aa); and Q9KZL3 Hypothetical protein SCO3031 from Streptomyces coelicolor (117 aa), FASTA scores: E(): 0.012, (30.159% identity in 126 aa overlap).;UniProt_AC=Q9CCJ9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	904676	906082	.	+	0	Locus=ML0763;Name=pmmA;Function=;Product=probable phosphomannomutase PmmA (PMM) (PHOSPHOMANNOSE MUTASE);Comments=ML0763, len: 468 aa. Probable pmmA, phosphomannomutase (EC 5.4.2.8), highly similar to O86374|Z95121|Rv3257c pmmA, probable phosphomannomutase from M. tuberculosis (465 aa),  fasta scores: E(): 9.2e-162, (83.1% identity in 468 aa overlap); and CAD95377| from M. bovis (465 aa). Similar to several e.g. MANB_ECOLI|P24175 manB phosphomannomutase from Escherichia coli (456 aa), fasta scores: E(): 6.9e-58, (39.0% identity in 451 aa). Also similar to ML0366 and ML0706 from M. leprae. Contains Pfam match to entry PF00408 PGM_PMM, Phosphoglucomutase/phosphomannomutase.;UniProt_AC=Q9CCJ7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	913624	915102	.	+	0	Locus=ML0771;Name=sahH;Function=THIOESTER HYDROLASE WHICH ACTING ON ETHER BOUNDS. COULD BE INVOLVED IN METHIONINE AND SELENOAMINO ACID METABOLISMS. ALSO INVOLVED IN ACTIVATED METHYL. CYCLE ADENOSYLHOMOCYSTEINE IS A COMPETITIVE INHIBITOR OF S-ADENOSYL-L-METHIONINE-DEPENDENT METHYL TRANSFERASE REACTIONS; THEREFORE ADENOSYLHOMOCYSTEINASE MAY PLAY A KEY ROLE IN THE CONTROL OF METHYLATIONS VIA REGULATION OF THE INTRACELLULAR CONCENTRATION OF ADENOSYLHOMOCYSTEINE [CATALYTIC ACTIVITY: S-ADENOSYL-L-HOMOCYSTEINE + H(2)O = ADENOSINE + L-HOMOCYSTEINE].;Product=putative S-adenosyl-L-homocysteine hydrolase SahH;Comments=ML0771, len: 492 aa. Probable sahH, adenosylhomocysteinase (EC 3.3.1.1), highly similar to Rv3248c|MTCY20B11.23c|SAHH_MYCTU|O08364 Probable sahH, adenosylhomocysteinase from M. tuberculosis (495 aa), fasta scores: E(): 1.1e-187, (91.4% identity in 489 aa), and CAD95368|Mb3276c from M. bovis (495 aa). Also highly similar to other adenosylhomocysteinases e.g. SAHH_TRIVA|P51540 adenosylhomocysteinase from Trichomonas vaginalis (486 aa), fasta scores: E(): 3.2e-121, (62.3% identity in 478 aa). Contains Pfam match to entry PF00670 AdoHcyase, S-adenosyl-L-homocysteine hydrolase. Contains PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. Contains PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. BELONGS TO THE ADENOSYLHOMOCYSTEINASE FAMILY.;UniProt_AC=Q9CCJ4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	916684	918372	.	+	0	Locus=ML0774;Name=mtrB;Function=;Product=probable two-component sensory transduction histidine kinase MtrB;Comments=ML0774, len: 562 aa. Probable mtrB, sensor-like histidine kinase (EC 2.7.3.-) (see citations below), highly similar to Q50496|U14909|Rv3245c mtrB, sensor-like histidine kinase Mycobacterium (567 aa), fasta scores: E(): 2.2e-197, (88.3% identity in 566 aa); and CAD95365|Mb3273c from M. bovis (567 aa). Also similar to others e.g. Q9KYW9|SCE33.14c PUTATIVE TWO-COMPONENT SYSTEM HISTIDINE KINASE from Streptomyces coelicolor (688 aa), fasta scores: E(): 5.1e-78, (46.507% identity in 544 aa overlap). And similar to ML0175, ML2124 and ML2440 from M. leprae. Contains hydrophobic, possible membrane-spanning region. Contains Pfam match to entry PF00672 DUF5, Domain found in bacterial signal proteins. Contains Pfam match to entry PF00512 signal, Histidine kinase. SIMILAR TO OTHER PROKARYOTIC SENSORY TRANSDUCTION HISTIDINE KINASES.;UniProt_AC=Q9CCJ1;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	925682	926164	.	+	0	Locus=ML0781;Name=ML0781;Function=;Product=conserved hypothetical protein;Comments=ML0781, len: 160 aa. Conserved hypothetical protein, highly similar to Rv3237c|MTCY20B11.12c|O05882|Z95121 Conserved hypothetical protein from Mycobacterium tuberculosis (160 aa), fasta scores: E(): 0, (80.6% identity in 160 aa): and CAD95357|Mb3265c from M. bovis (160 aa). Similar to other hypothetical bacterial proteins and more weakly to putative potassium channels e.g. Q9RV81|AE001964|DR1148 conserved hypothetical protein from Deinococcus radiodurans  (175 aa), fasta scores: E(): 1.1e-19, (38.0% identity in 158 aa); Q58752|YD57_METJA Putative potassium channel protein from Methanococcus jannaschii  (343 aa), fasta scores: E(): 0.0081, (32.000% identity in 75 aa overlap).;UniProt_AC=Q9CCI6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	492715	493824	.	-	0	Locus=ML0396c;Name=ino2;Function=;Product=Probable myo-inositol-1-phosphate synthase Ino2 (Inositol 1-phosphate synthetase) (D-glucose 6-phosphate cycloaldolase) (Glucose 6-phosphate cyclase) (Glucocycloaldolase);Comments=ML0396c, len: 369 aa. Probable ino2 (alternate gene name: tbINO), myo-inositol-1-phosphate synthase (EC 5.5.1.4) (see citations below). Identical to ML2692 a possible orthologue of M. tuberculosis ino1. Possibly a paralogue of Rv0046c|P71703|AL123456 ino1, myo-inositol-1-phosphate synthase from M. tuberculosis (367 aa), Fasta scores: E(): 0, (91.8% identity in 366 aa overlap). Highly similar to other bacterial myo-inositol-1-phosphate synthase and hypothetical proteins e.g. Q8NLE6 Myo-inositol-1-phosphate synthase from Corynebacterium glutamicum (363 aa), Fasta scores: E(): 0, (73.9% identity in 361 aa overlap); and Q9X8T5|SCH24_21c Hypothetical protein from Streptomyces coelicolor (360 aa).  Previously sequenced as Q57240|U00015 (369 aa), Fasta scores: E(): 0, (100.0% identity in 369 aa overlap). Contains Pfam match to entry PF01658 Inos-1-P_synth, Myo-inositol-1-phosphate synthase.;UniProt_AC=Q57240;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2043781	2044290	.	-	0	Locus=ML1695c;Name=ilvN;Function=;Product=PROBABLE ACETOLACTATE SYNTHASE (SMALL SUBUNIT) ILVN (ACETOHYDROXY-ACID SYNTHASE) (AHAS) (ALS);Comments=ML1695c, len: 169 aa. Probable ilvN, acetolactate synthase small subunit (EC 4.1.3.18). Highly similar to many acetolactate synthases, small subunit, involved in valine and isoleucine biosynthesis, including: Mycobacterium avium SW:ILVH_MYCAV (Q59499) (167 aa), Fasta scores: E(): 0, 78.9% identity in 166 aa overlap and Mycobacterium tuberculosis Rv3002c SW:ILVH_MYCTU (O53249) (168 aa), Fasta scores: E(): 0, 83.5% identity in 164 aa overlap. Contains Pfam match to entry PF01842 ACT, ACT domain.;UniProt_AC=O33113;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	630654	631091	.	+	0	Locus=ML0519;Name=aroD;Function=INVOLVED AT THE THIRD STEP IN THE BIOSYNTHESIS OF CHORISMATE WITHIN THE BIOSYNTHESIS OF AROMATIC AMINO ACIDS (THE SHIKIMATE PATHWAY). CATALYZE A TRANS-DEHYDRATION VIA AN ENOLATE INTERMEDIATE [CATALYTIC ACTIVITY: 3-DEHYDROQUINATE = 3-DEHYDROSHIKIMATE + H(2)O].;Product=3-dehydroquinate dehydratase AroD (AroQ) (3-dehydroquinase) (Type II DHQase);Comments=ML0519, len: 145 aa. aroD, 3-dehydroquinate dehydratase (EC 4.2.1.10), highly similar to AROQ_MYCTU|P36918|Rv2537c aroD, 3-dehydroquinate dehydratase from M. tuberculosis (146 aa), Fasta scores: E(): 0, (85.9% identity in 142 aa overlap); and CAD94751|Mb2566c from M. bovis (147 aa). Similar to many e.g. AROQ_CORPS|P96750 aroQ, 3-dehydroquinate dehydratase from Corynebacterium pseudotuberculosis (146 aa), Fasta scores: E(): 6.7e-33, (61.0% identity in 136 aa overlap). Contains Pfam match to entry PF01220 DHquinase_II, Dehydroquinase class II. Contains PS01029 Dehydroquinase class II signature. Belongs to the type-II 3-dehydroquinase family.;UniProt_AC=Q9CCS3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	554334	555053	.	-	0	Locus=ML0454c;Name=pgsA;Function=;Product=Probable PI synthase PgsA1 (phosphatidylinositol synthase) (CDP-diacylglyceride--inositol3-phosphatidyltransferase) ;Comments=ML0454c, len: 239 aa. Probable pgsA1 (previously known as pgsA), PI synthase/CDP-diacylglyceride--inositol phosphatidyltransferase (EC 2.7.8.11), transmembrane protein, highly similar to Rv2612c|O06202|AL123456 pgsA1 probable PI synthase from M. tuberculosis (217 aa), Fasta scores: E(): 0, (79.3% identity in 213 aa overlap); and Q9F7Y9|PGSA phosphatidylinositol synthase from Mycobacterium smegmatis (222 aa). Shows weak similarity to PGSA_ECOLI|P06978 pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase from Escherichia coli  (738 aa), BlastP Expect 8.6. Previously sequenced as O07149|Z96801 (239 aa), Fasta scores: E(): 0, (100.0% identity in 239 aa overlap). Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. Contains PS00379 CDP-alcohol phosphatidyltransferases signature. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. Note that in Mycobacterium smegmatis, the psgA homologue is essential to the survival of the bacteria and seems cannot be compensated by any other enzyme of Mycobacterium smegmatis.;UniProt_AC=O07149;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	672088	673107	.	+	0	Locus=ML0555;Name=ribG;Function=INVOLVED IN RIBOFLAVIN BIOSYNTHESIS (AT THE SECOND AND THIRD STEPS). CONVERTS 2,5-DIAMINO-6-(RIBOSYLAMINO)-4(3H)-PYRIMIDINONE 5'-PHOSPHATE INTO 5-AMINO-6-(RIBOSYLAMINO)-2,4(1H,3H)-PYRIMIDINEDIONE 5'-PHOSPHATE [CATALYTIC ACTIVITY 1: 2,5-DIAMINO-6-HYDROXY-4-(5-PHOSPHORIBOSYLAMINO)PYRIMIDINE + H(2)O = 5-AMINO-6-(5-PHOSPHORIBOSYLAMINO)URACIL + NH(3)] [CATALYTIC ACTIVITY 2: 5-AMINO-6-(5-PHOSPHORIBITYLAMINO)URACIL + NADP(+) = 5-AMINO-6-(5-PHOSPHORIBOSYLAMINO)URACIL + NADPH].;Product=Probable bifunctional riboflavin-specific deaminase/reductase RibG: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) and 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase);Comments=ML0555, len: 339 aa. Probable ribG, bifunctional riboflavin biosynthesis protein, including diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) uracil reductase (EC 3.5.4.26 and 1.1.1.193), highly similar to RIBD_MYCTU|P71677|Rv1409 ribG, bifunctional riboflavin biosynthesis protein from M. tuberculosis (339 aa), Fasta scores: E(): 0, (78.2% identity in 339 aa overlap); and CAD94305|Mb1444 from M. bovis (339 aa). Similar to many e.g. RIBD_BACSU|P17618 ribD, diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)-uracil reductase from Bacillus subtilis (361 aa), Fasta scores: E(): 7.9e-33, (39.2% identity in 357 aa overlap). Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region. Contains Pfam match to entry PF01872 RibD_C, RibD C-terminal domain. Contains PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. IN THE N-TERMINAL SECTION; BELONGS TO THE CYTIDINE AND DEOXYCYTIDYLATE DEAMINASES FAMILY. IN THE C-TERMINAL SECTION; BELONGS TO THE HTP REDUCTASE FAMILY.;UniProt_AC=Q9CCP8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	921723	924545	.	+	0	Locus=ML0779;Name=secA1;Function=;Product=PROBABLE PREPROTEIN TRANSLOCASE SECA1 SUBUNIT;Comments=ML0779, len: 940 aa. Probable secA1, preprotein translocase subunit, component of secretion apparatus (see citations below), highly similar to Rv3240c|MTCY20B11.15c|SEA1_MYCTU|O05885 Probable secA1, preprotein translocase subunit from Mycobacterium tuberculosis (949 aa), fasta scores: E(): 0, (87.5% identity in 949 aa); and CAD95360|Mb3268c from M. bovis (949 aa). Highly similar to many e.g. P71533|SECA_MYCSM Preprotein translocase secA subunit from M. smegmatis (957 aa), fasta scores: E(): 0, (77.651% identity in 962 aa overlap). Also similar to ML2082 from M. leprae. Contains Pfam match to entry PF01043 SecA_protein, SecA protein, amino terminal region. Contains PS01312 Protein secA signatures. BELONGS TO THE SECA FAMILY. PART OF THE PROKARYOTIC PROTEIN TRANSLOCATION APPARATUS WHICH COMPRISE SECA, SECD|ML0487, SECE|ML1907, SECF|ML0488, SECG|ML0577 AND SECY|ML1833.;UniProt_AC=P57996;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	405519	407144	.	+	0	Locus=ML0317;Name=groEL2;Function=;Product=65 kDa chaperonin 2 GroEL2 (Protein Cpn60-2) (groEL protein 2) (65 kDa antigen) (Heat shock protein 65) (Cell wall protein A) (Antigen A).;Comments=ML0317, len: 541 aa. Probable groEL2 (alternate gene names: groL2, groEL-2, hsp65, hsp60), 65 kDa chaperonin 2 (see citations below), highly similar to Rv0440|CH62_MYCTU|P06806 groEL2, 60 kDa chaperonin 2 from M. tuberculosis (539 aa), Fasta scores: E(): 0, (94.8% identity in 541 aa overlap); and other bacterial chaperonin proteins. Previously sequenced as CH62_MYCLE|P09239 (540 aa), Fasta scores: E(): 0, (100.0% identity in 540 aa overlap). Also similar to ML0381 from M. leprae. Contains Pfam match to entry PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family. Contains PS00296 Chaperonins cpn60 signature. In M. tuberculosis purified 65 kDa antigen can elicit a strong delayed-type hypersensitivity reaction when infected in experimental animals.  This protein is one of the major immunoreactive proteins of mycobacteria. This antigen contains epitopes that are common to various species of mycobacteria. Belongs to the chaperonin (hsp60) family.;UniProt_AC=P09239;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	837680	838768	.	+	0	Locus=ML0700;Name=add;Function=;Product=Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE);Comments=ML0700, len: 362 aa. Probable add, adenosine deaminase (EC 3.5.4.4), highlt similar to O53365|AL123456|Rv3313c add, probable adenosine deaminase from M. tuberculosis (365 aa), Fasta scores: E(): 0, (88.2% identity in 356 aa overlap). Similar to many e.g. Q9AK25|ADD5_STRCO Probable adenosine deaminase 5 from Streptomyces coelicolor (396 aa), fasta scores: E(): 9.9e-99, 66.856% identity in 353 aa overlap); and ADD_ECOLI|P22333 add, adenosine deaminase from Escherichia coli (333 aa), Fasta scores: E(): 6.8e-19, (29.7% identity in 340 aa overlap). Previously sequenced as Q49907|U00022 (332 aa), Fasta scores: E(): 0, (99.7% identity in 332 aa overlap). Contains Pfam match to entry PF00962 A_deaminase, Adenosine/AMP deaminase. BELONGS TO THE ADENOSINE AND AMP DEAMINASES FAMILY.;UniProt_AC=Q9CCL9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1035227	1035583	.	+	0	Locus=ML0871;Name=ML0871;Function=;Product=conserved hypothetical protein;Comments=ML0871, len: 118 aa. Similar to Mycobacterium tuberculosis hypothetical 12.5 kDa protein Rv2204c or MTCY190.15C SW:YM04_MYCTU (Q10393) (118 aa) fasta scores: E(): 0, 92.4% identity in 118 aa. Similar to many hypothetical proteins e.g. Streptomyces coelicolor hypothetical 12.4 kDa protein SC6G10.34C TR:Q9X819 (EMBL:AL049497) (118 aa) fasta scores: E(): 0, 73.7% id in 118 aa. Contains Pfam match to entry PF01521 HesB-like, HesB-like domain. Contains PS01152 Hypothetical hesB/yadR/yfhF family signature. BELONGS TO THE HESB/YADR/YFHF FAMILY. ;UniProt_AC=Q9CCF5;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2324570	2325577	.	-	0	Locus=ML1938c;Name=lytB2;Function=;Product=PROBABLE LYTB-RELATED PROTEIN LYTB2;Comments=ML1938c, len: 335 aa. Probable LytB2-related protein. Similar to M. tuberculosis LytB protein homolog lytB2 Rv1110 SW:LYB1_MYCTU (O53458) (335 aa), Fasta scores: E(): 0, 82.9% identity in 333 aa overlap, and to many others e.g. Escherichia coli LytB protein SW:LYTB_ECOLI (P22565) (316 aa), Fasta scores: E(): 0, 51.5% identity in 309 aa overlap.;UniProt_AC=Q9X781;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	468133	469299	.	+	0	Locus=ML0375;Name=alr;Function=;Product=Probable alanine racemase Alr;Comments=ML0375, len: 388 aa. Probable alr, alanine racemase (EC 5.1.1.1), highly similar to Rv3423c|ALR_MYCTU|Q50705 alr, probable alanine racemase from M. tuberculosis (408 aa), Fasta scores: E(): 0, (84.6% identity in 382 aa overlap). Highly similar to other alanine racemases e.g. ALR_MYCSM|P94967 alr, alanine racemase from Mycobacterium smegmatis (389 aa), Fasta scores: E(): 0, (67.2% identity in 378 aa overlap); and O86786|ALR_STRCO|SC6G4.23 from Streptomyces coelicolor (391 aa). Previously sequenced as ALR_MYCLE|P38056 (388 aa), Fasta scores: E(): 0, (99.7% identity in 388 aa overlap). Contains 2 Pfam matches to entry PF00842 Ala_racemase, Alanine racemase. Belongs to the alanine racemase family.;UniProt_AC=P38056;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	627742	628965	.	+	0	Locus=ML0516;Name=aroF;Function=;Product=Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase).;Comments=ML0516, len: 407 aa. aroF, chorismate synthase (EC 4.6.1.4), highly similar to AROC_MYCTU|P95013|Rv2540c aroF, chorismate synthase from M. tuberculosis (401 aa), Fasta scores: E(): 0, (88.0% identity in 401 aa overlap); and CAD94754|Mb2569c from M. bovis (401 aa). Similar to many e.g. Q9KXQ4|AROC_STRCO|SC9C5.20c from Streptomyces coelicolor (394 aa), E(): 6.3e-98, (65.365% identity in 384 aa overlap). Contains Pfam match to entry PF01264 Chorismate_synt, Chorismate synthase. Contains PS00788 Chorismate synthase signature 2. Contains PS00789 Chorismate synthase signature 3. Contains PS00787 Chorismate synthase signature 1. Belongs to the Chorismate synthase family. Cofactor: Reduced flavin.;UniProt_AC=Q9CCS6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	606840	608609	.	+	0	Locus=ML0501;Name=aspS;Function=;Product=Probable aspartyl-tRNA synthetase AspS (aspartate--tRNA ligase) (AspRS) (aspartic acid translase);Comments=ML0501, len: 589 aa. Probable aspS, aspartyl-tRNA synthetase (EC 6.1.1.12), highly similar to SYD_MYCTU|Q50649|Rv2572c aspS, aspartyl-tRNA synthetase from M. tuberculosis  (596 aa), Fasta scores: E(): 0, (88.0% identity in 592 aa overlap); and CAD94787|Mb2602c from M. bovis (611 aa). And highly similar to many e.g. Q8FT19 Putative aspartyl-tRNA synthetase from Corynebacterium efficiens (617 aa), fasta scores: E(): 3.8e-190, (71.549% identity in 594 aa overlap); and SYD_ECOLI|P21889 aspS, aspartyl-tRNA synthetase from Escherichia coli (590 aa), Fasta scores: (46.8% identity in 583 aa overlap). Previously sequenced as SYD_MYCLE|P36429 (589 aa), Fasta scores: E(): 0, (99.8% identity in 589 aa overlap). Contains Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N). Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. Belongs to the class-II aminoacyl-tRNA synthetase family.;UniProt_AC=P36429;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	715032	715979	.	-	0	Locus=ML0590c;Name=ML0590c;Function=;Product=Possible unidentified antibiotic-transport ATP-binding protein ABC transporter;Comments=ML0590c, len: 315 aa. Possible unidentified antibiotic-transport ATP-binding protein ABC transporter (see citation below), highly similar to O53149|AL123456|Rv1458c Possible unidentified antibiotic-transport ATP-binding protein ABC transporter from M. tuberculosis (313 aa), Fasta scores: E(): 3.1e-109, (88.0% identity in 308 aa overlap). Similar to many e.g. Q9XAC8 Putative ABC transporter, ATP-binding protein from Streptomyces coelicolor (307 aa), fasta scores: E(): 9e-68, (59.539% identity in 304 aa overlap). Previously sequenced as Q49707|U00013 (315 aa), Fasta scores: E(): 0, (100.0% identity in 315 aa overlap). Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature. Belongs to the ATP-binding transport protein family.;UniProt_AC=Q49707;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	888794	890971	.	-	0	Locus=ML0747c;Name=ctpC;Function=;Product=Probable metal cation-transporting P-type ATPase C CtpC;Comments=ML0747c, len: 725 aa. Probable ctpC, metal cation-transport ATPase P-type (EC 3.6.3.-), integral membrane protein, highly similar to Rv3270|MTCY71.10|CTPC_MYCTU|P96875 ctpC, metal cation-transport ATPase P-type from Mycobacterium tuberculosis (718 aa), fasta scores: E(): 0, (86.0% identity in 713 aa), and to P77894|CTPV_MYCTU Probable cation-transporting ATPase from M. tuberculosis (770 aa), fasta scores: E(): 2.9e-70, (36.970% identity in 779 aa overlap). Similar to other metal transporting ATPases e.g. Q8FUE3 Putative copper-transporting ATPase from Corynebacterium efficiens   (578 aa), fasta scores: E(): 3.6e-72, (40.702% identity in 570 aa overlap). Contains hydrophobic, possible membrane-spanning region. Contains 2 Pfam matches to entry PF00122 E1-E2_ATPase, E1-E2 ATPase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00154 E1-E2 ATPases phosphorylation site. Contains PS01229 Hypothetical cof family signature 2. BELONGS TO THE CATION TRANSPORT ATPASES FAMILY (E1-E2 ATPASES), SUBFAMILY IB.;UniProt_AC=Q9CCL1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	412124	413545	.	+	0	Locus=ML0323;Name=cysS1;Function=;Product=Probable cysteinyl-tRNA synthase 1 CysS1 (Cysteine--tRNA ligase 1) (CysRS 1);Comments=ML0323, len: 473 aa. Probable cysS1, cysteinyl-tRNA synthetase (EC 6.1.1.16), highly similar to Rv3580c|SYC1_MYCTU|P96862 cysS1, cysteinyl-tRNA synthetase from M. tuberculosis (469 aa), Fasta scores: E(): 0, (86.5% identity in 467 aa overlap). Similar to many others e.g. SYC_ECOLI|P21888 cysS, cysteinyl-tRNA synthetase from Escherichia coli (461 aa), Fasta scores: E(): 0, (42.0% identity in 460 aa overlap). Also similar to ML1302 from M. leprae. Contains Pfam match to entry PF01406 tRNA-synt_1e, tRNA synthetases class I (C). Belongs to the class-I aminoacyl-tRNA synthetase family. Strongly similar to methionyl-tRNA synthetase.;UniProt_AC=P57990;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	827878	829113	.	-	0	Locus=ML0691c;Name=dacB1;Function=;Product=Probable D-alanyl-D-alanine carboxypeptidase DacB1 (PENICILLIN-BINDING PROTEIN) (DD-PEPTIDASE) (DD-CARBOXYPEPTIDASE) (PBP) (DD-TRANSPEPTIDASE) (SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE) (D-AMINO ACID HYDROLASE) ;Comments=ML0691c, len: 411 aa. Probable dacB1, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein) (EC 3.4.16.4), highly similar to O53380|AL123456|Rv3330 dacB1, D-alanyl-D-alanine carboxypeptidase from M. tuberculosis (405 aa), Fasta scores: E(): 0, (77.2% identity in 416 aa overlap); and CAD95475|Mb3363 from M. bovis (405 aa). Similar to several e.g. Q8FRR0 Putative penicillin-binding protein from Corynebacterium efficiens (447 aa), fasta scores: E(): 1.6e-50, (45.283% identity in 371 aa overlap). Previously sequenced as Q49917|U00022 (228 aa), Fasta scores: E(): 0, (100.0% identity in 228 aa overlap). Contains a probable N-terminal signal sequence. Contains Pfam match to entry PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase. BELONGS TO PEPTIDASE FAMILY S11; ALSO KNOWN AS THE D-ALANYL-D-ALANINE CARBOXYPEPTIDASE 1 FAMILY;UniProt_AC=Q9CCM2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	658334	659593	.	+	0	Locus=ML0543;Name=dfp;Function=;Product=Probable DNA/pantothenate metabolism flavoprotein homolog Dfp;Comments=ML0543, len: 419 aa. Probable dfp, DNA/pantothenate metabolism flavoprotein homolog, highly similar to DFP_MYCTU|P71661|Rv1391 probable dfp, DNA/pantothenate metabolism flavoprotein homolog from M. tuberculosis (418 aa), Fasta scores: E(): 1.8e-139, (87.0% identity in 409 aa overlap); and CAD94287|Mb1426 from M. bovis (418 aa). Similar to many e.g. DFP_ECOLI|P24285 dfp, DNA/pantothenate metabolism flavoprotein from Escherichia coli (430 aa), Fasta scores: E(): 0, (39.7% identity in 408 aa overlap). Contains match to Pfam entry PF02441 Flavoprotein.;UniProt_AC=Q9CCQ5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	810693	811541	.	+	0	Locus=ML0674;Name=folD;Function=NECESSARY FOR THE BIOSYNTHESIS OF PURINES, THYMYDYLATE, METHIONINE, HISTIDINE, PANTOTHENATE, AND FORMYL TRNA-MET [CATALYTIC ACTIVITY: 5,10-METHYLENETETRAHYDROFOLATE + NADP(+) = 5,10-METHENYLTETRAHYDROFOLATE + NADPH] [CATALYTIC ACTIVITY: 5,10-METHENYLTETRAHYDROFOLATE + H(2)O = 10-FORMYLTETRAHYDROFOLATE].;Product=Probable bifunctional protein fold: methylenetetrahydrofolate dehydrogenase + methenyltetrahydrofolate cyclohydrolase FolD;Comments=ML0674, len: 282 aa. Probable folD, bifunctional enzyme include methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5) and methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9), highly similar to O50385|AL123456|Rv3356c Probable folD, bifunctional enzyme from M. tuberculosis (281 aa), Fasta scores: E(): 0, (86.5% identity in 281 aa overlap); CAD95537|3391c from M. bovis (281 aa). Similar to many e.g. FOLD_ECOLI|P24186 folD, bifunctional methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase from Escherichia coli (287 aa), Fasta scores: E(): 0, (40.8% identity in 277 aa overlap). Previously sequenced as O32879|Z98271 (282 aa), Fasta scores: E(): 0, (99.6% identity in 282 aa overlap). Contains Pfam match to entry PF00763 THF_DHG_CYH, Tetrahydrofolate dehydrogenase/cyclohydrolase. SIMILAR TO OTHER DEHYDROGENASE/CYCLOHYDROLASE ENZYMES OR DOMAINS.;UniProt_AC=O32879;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	634644	637496	.	+	0	Locus=ML0524;Name=ML0524;Function=;Product=Probable amino acid decarboxylase;Comments=ML0524, len: 950 aa. Probable amino acid decarboxylase (EC 4.1.1.-), highly similar to P95022|AL123456|Rv2531c Probable amino acid decarboxylase from M. tuberculosis (947 aa), Fasta scores: E(): 0, (86.4% identity in 951 aa overlap); and CAD94745|Mb2560c from M. bovis (947 aa). Similar to decarboxylases of ornithine/arginine/lysine e.g. Q9I2S7|PA1818 Probable Orn/Arg/Lys decarboxylase from Pseudomonas aeruginosa (751 aa), FASTA scores: E(): 4.9e-20, (28.807% identity in 729 aa overlap); and DCOR_ECOLI|P21169 speC, ornithine decarboxylase (constitutive) from Escherichia coli (731 aa), Fasta scores: E(): 3e-16, (26.8% identity in 650 aa overlap). Contains Pfam match to entry PF01276 OKR_DC_1, Orn/Lys/Arg decarboxylase. Seems to belong to the family of ornithine, lysine and arginine decarboxylases. Note that previously known as adi.;UniProt_AC=Q9CCR8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	410871	411596	.	+	0	Locus=ML0321;Name=ispD;Function=Involved in the terpenoid biosynthesis pathway (at the third step). Catalyzes the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from 2C-methyl-D-erythritol 4-phosphate. [Catalytic activity: CTP and CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol].;Product=Probable 4-diphosphocytidyl-2C-methyl-D-erythritol synthase IspD (2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase) (MEP cytidylyltransferase) (MCT);Comments=ML0321, len: 241 aa. Probable ispD, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase (EC 2.7.7.-), highly similar to Rv3582c|YZ82_MYCTU|P96864 probable ispD, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase from M. tuberculosis (231 aa), Fasta scores: E(): 0, (66.0% identity in 241 aa overlap). Similar to other bacterial 4-diphosphocytidyl-2C-methyl-D-erythritol synthases e.g. CAB77327|AL160331 from Streptomyces coelicolor (270 aa), Fasta scores: E(): 4.3e-25, (45.0% identity in 240 aa overlap) and AAF43207|AF230736 ispD from Escherichia coli (236 aa), Fasta scores: E(): 0.0016, (36.1% identity in 244 aa overlap). Contains the PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature and Pfam match to entry PF01128 UPF0007, Uncharacterized protein family UPF0007. Belongs to the IspD family.;UniProt_AC=Q9CCW6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	742717	744657	.	+	0	Locus=ML0611;Name=lepA;Function=;Product=Probable GTP-binding protein LepA;Comments=ML0611, len: 646 aa. Probable lepA, GTP-binding protein (a protein of unknown function, but apparently with membrane-related functions and very similar to protein synthesis elongation factors; see citations below). Highly similar to LEPA_MYCTU|P71739|Rv2404c lepA, putative GTP-binding protein from M. tuberculosis (653 aa), Fasta scores: E(): 0, (88.0% identity in 649 aa overlap); and CAD97288|Mb2427c from M. bovis (653 aa). Similar to many e.g. LEPA_BACSU|P37949 lepA, GTP-binding protein from Bacillus subtilis (612 aa), Fasta scores: E(): 5.5e-144, (56.8% identity in 613 aa overlap). Previously sequenced as LEPA_MYCLE|P53530 (646 aa), Fasta scores: E(): 0, (99.8% identity in 646 aa overlap). Show weak similarity to ML1498, ML1877 and ML1878 from M. leprae. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family. Contains PS00301 GTP-binding elongation factors signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the GTP-binding elongation factor family, LepA subfamily.;UniProt_AC=P53530;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	493940	495748	.	-	0	Locus=ML0397c;Name=ML0397c;Function=;Product=Possible transporter protein;Comments=ML0397c, len: 602 aa. Possible transporter protein. Similar at the N-terminus to C-terminal (transporter) part of Q9RDI0 bifunctional carbohydrate binding and transport protein from Streptomyces coelicolor A3(2) (651 aa), Fasta scores: E(): 4.4e-35, (40.4% identity in 334 aa overlap). C-terminal half is similar to sugar permeases e.g. Escherichia coli AraH, L-arabinose transport system permease protein, SW:ARAH_ECOLI (P08532) (329 aa), Fasta scores: E(): 1.1e-26, 36.0% identity in 297 aa overlap. The N-terminal half shows weak similarity to other proteins containing PAS and DUF9 domains. There is a possibility that this is a signal transduction protein. Previously sequenced as Q49739|U00015 (577 aa), Fasta scores: E(): 0, (99.8% identity in 577 aa overlap). The C-terminal half is similar to ML1419 from M. leprae. The N-terminal half shows some similarity to ML1750 from M. leprae. Contains hydrophobic, possible membrane-spanning regions in the C-terminal half. Contains Pfam match to entry PF00989 PAS, PAS domain. Contains Pfam match to entry PF00990 DUF9, Domain of unknown function. Contains PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.;UniProt_AC=Q9CCU8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	528622	529428	.	-	0	Locus=ML0429c;Name=ML0429c;Function=;Product=Probable short-chain type dehydrogenase/reductase;Comments=ML0429c, len: 268 aa. Probable ala-rich oxidoreductase, short-chain dehydrogenase/reductase (EC 1.-.-.-), highly similar to Rv2509|O06172|AL123456 putative ala-rich oxidoreductase from M. tuberculosis (268 aa), Fasta scores: E(): 0, (88.8% identity in 267 aa overlap). Similar to many putative dehydrogenases e.g O86553|SC1F2.16c putative dehydrogenase from Streptomyces coelicolor (276 aa), FASTA scores: opt: 492, E(): 9.5e-23, (38.15% identity in 262 aa overlap). Previously sequenced as O07709|Z97179 (268 aa), Fasta scores: E(): 0, (100.0% identity in 268 aa overlap). Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature. Belongs to the short-chain dehydrogenase/reductase (SDR) family.;UniProt_AC=O07709;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	558364	559269	.	-	0	Locus=ML0458c;Name=ML0458c;Function=;Product=Possible oxidoreductase;Comments=ML0458c, len: 301 aa. Possible oxidoreductase (EC 1.-.-.-), similar to several putative oxidoreductase from both bacteria and eukaryotes e.g. SPBC215.11C|O94315|AL033534 putative aldo-keto reductase from Schizosaccharomyces pombe (306 aa), Fasta scores: E(): 0, (53.5% identity in 288 aa overlap); and P25906|YDBC_ECOLI putative dehydrogenase from Escherichia coli K12 (286 aa). Previously sequenced as O07152|Z96801 (306 aa), Fasta scores: E(): 0, (100.0% identity in 301 aa overlap). Contains 2 Pfam matches to entry PF00248 aldo_ket_red, Aldo/keto reductase family.;UniProt_AC=Q9CCT9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	673151	674680	.	-	0	Locus=ML0556c;Name=ML0556c;Function=INVOLVED IN TRANSPORT OF AMINOGLYCOSIDES AND TETRACYCLINE ACROSS THE MEMBRANE (EXPORT): DRUG RESISTANCE BY AN EXPORT MECHANISM (CONFERES RESISTANCE TO TOXIC COMPOUNDS BY REMOVING THEM FOR THE CELLS). RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE.;Product=Aminoglycoside/tetracycline-transport integral membrane protein;Comments=ML0556c, len: 509 aa. Aminoglycoside/tetracycline-transport integral membrane protein (see citation below), member of major facilitator superfamily (MFS), highly similar to P71678|AL123456|Rv1410c Aminoglycoside/tetracycline-transport integral membrane protein from M. tuberculosis (518 aa), Fasta scores: E(): 0, (82.0% identity in 506 aa overlap); and CAD94306|Mb1445c from M. bovis (518 aa). Similar to others e.g. P96712|D50098 bmr3, multidrug transporter from Bacillus subtilis (512 aa), Fasta scores: E(): 5.4e-24, (27.1% identity in 446 aa overlap). Also similar to ML1562. Contains hydrophobic, probable membrane-spanning regions. Contains Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter. Contains PS00216 Sugar transport proteins signature 1. Note that the ML0556c-ML0557c operon seems transcribed from two promoters in Mycobacterium bovis BCG (see Bigi et al., 2000);UniProt_AC=Q9CCP7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	657981	658313	.	+	0	Locus=ML0542;Name=rpoZ;Function=;Product=Probable DNA-directed RNA polymerase omega chain RpoZ (Transcriptase omega chain) (RNA polymerase omega subunit);Comments=ML0542, len: 110 aa. Probable rpoZ, DNA-directed RNA polymerase omega chain (EC 2.7.7.6), highly similar to YD90_MYCTU|P71660|Rv1390 rpoZ, DNA-directed RNA polymerase omega chain from M. tuberculosis (110 aa), Fasta scores: E(): 0, (90.0% identity in 110 aa overlap); and CAD94286|Mb1425 from M. bovis (110 aa). Also similar to Q9KXS1|RPOZ_STRCO Probable DNA-directed RNA polymermerase omega chain from Streptomyces coelicolor (90 aa), fasta scores: E(): 8.4e-19, (71.250% identity in 80 aa overlap). Subunit: CONSISTS OF A SIGMA FACTOR AND THE RNAP CORE ENZYME WHICH IS COMPOSED OF 2 ALPHA CHAINS, 1 BETA CHAIN, 1 BETA' CHAIN AND 1 OMEGA CHAIN. Belongs to the RNA polymerase omega chain family.;UniProt_AC=Q9CCQ6;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	718689	721298	.	+	0	Locus=ML0593;Name=ML0593;Function=;Product=Conserved hypothetical protein;Comments=ML0593, len: 869 aa. Conserved hypothetical protein, highly similar to YE61_MYCTU|O53152|Rv1461 Conserved hypothetical protein from M. tuberculosis (846 aa), Fasta scores: E(): 0, 54.3% identity in 920 aa overlap. N- and C-termini are similar to various bacterial hypothetical proteins e.g. Streptomyces coelicolor SCC22.07C, conserved hypothetical protein, TR:Q9XAD1 (EMBL:AL096839) (473 aa), Fasta scores: E(): 0, 45.5% identity in 853 aa overlap. Contains an intein from amino acids 202-587 inclusive. The intein is different to the one in the M. tuberculosis orthologue and at a different relative position. C-terminal half is similar to ML0594. Previously sequenced as SW:YE61_MYCLE (Q49689) (869 aa), Fasta scores: E(): 0, 99.9% identity in 869 aa overlap. Contains Pfam match to entry PF01458 UPF0051, Uncharacterized protein family (UPF0051). Contains PS00881 Protein splicing signature.;UniProt_AC=Q49689;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	834667	836421	.	-	0	Locus=ML0697c;Name=sdhA;Function=;Product=Probable succinate dehydrogenase (flavoprotein subunit) SdhA (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE);Comments=ML0697c, len: 584 aa. Probable sdhA, flavoprotein of succinate dehydrogenase SdhA subunit (EC 1.3.99.1), highly similar to O53370|AL123456|Rv3318 sdhA, succinate dehydrogenase from M. tuberculosis (590 aa), Fasta scores: E(): 0, (92.5% identity in 590 aa overlap); and CAD95440| from M. bovis (590 aa). Similar to many e.g. SW:DHSA_ECOLI (P10444) sdhA, succinate dehydrogenase flavoprotein subunit from Escherichia coli (588 aa), Fasta scores: E(): 0, (48.6% identity in 589 aa overlap). Previously sequenced as Q49924|U00022 (401 aa), Fasta scores: E(): 0, (97.2% identity in 395 aa overlap). Contains Pfam match to entry PF00890 FAD_binding_2, FAD binding domain. Contains PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. COFACTOR: FAD. SIMILAR TO THE FLAVOPROTEIN SUBUNITS OF OTHER SPECIES SUCCINATE DEHYDROGENASE AND OF FUMARATE REDUCTASE. PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC ANCHOR PROTEIN.;UniProt_AC=Q9CCM1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	926169	927326	.	+	0	Locus=ML0782;Name=ML0782;Function=;Product=probable conserved integral membrane transport protein;Comments=ML0782, len: 385 aa. Probable conserved integral membrane transport protein, possibly cation (Na/H) transporter, highly similar to Rv3236c|MTCY20B11.11c|O05881|Z95121 Probable conserved integral membrane transport protein from M. tuberculosis (385 aa), fasta scores: E(): 3.8e-117, (81.8% identity in 385 aa); and CAD95356|Mb3264c from M. bovis (385 aa). Similar to others e.g. O69958 Putative transmembrane transport protein from Streptomyces coelicolor (411 aa), fasta scores: E(): 1.5e-69, (51.882% identity in 372 aa overlap); and weakly similar to KEFB_ECOLI|P45522 glutathione-regulated potassium-efflux system protein kefB from Escherichia coli, fasta scores: E(): 4.7e-13, (26.0% identity in 362 aa). Contains hydrophobic, possible membrane-spanning regions. SEEMS TO BELONG TO THE CPA2 FAMILY.;UniProt_AC=Q9CCI5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	457993	459384	.	+	0	Locus=ML0366;Name=mrsA;Function=;Product=Probable phospho-sugar mutase / MrsA protein homolog;Comments=ML0366, len: 463 aa. Probable mrsA, phosphoglucomutase or phosphomannomutase (EC 5.4.2.-), highly similar to Rv3441c|O06258|AL123456 mrsA, phosphoglucomutase or phosphomannomutase from M. tuberculosis (448 aa), Fasta scores: E(): 0, (87.6% identity in 445 aa overlap). Similar to many other phospho-sugar mutases e.g. Q53876|SC6G4.14 putative phospho-sugar mutase (similar to phosphomannomutase) from Streptomyces coelicolor (452 aa), Fasta scores: E(): 0, 59.3% identity in 452 aa overlap) and MANB_SALTY|P26341 manB, phosphomannomutase from Salmonella typhimurium (264 aa), and Q9KG46|BH0267 phosphoglucosamine mutase from Bacillus halodurans (447 aa), Fasta scores: E(): 0, (47.2% identity in 445 aa overlap). Previously sequenced as Q49869|U00020 (463 aa), Fasta scores: E(): 0, (100.0% identity in 463 aa overlap). Also similar to ML0706 and ML0763 from M. leprae. Contains Pfam match to entry PF00408 PGM_PMM, Phosphoglucomutase/phosphomannomutase. Contains PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. Belongs to the phosphohexose mutases family.;UniProt_AC=Q49869;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1151513	1152691	.	+	0	Locus=ML0985;Name=ML0985;Function=;Product=possible glycosyltransferase;Comments=ML0985, len: 392 aa. Possible glycosyltransferase (EC 2.-.-.-). Identical to the previously sequenced Mycobacterium leprae possible glycosyl transferase TR:Q49841 (EMBL:Z94723) (392 aa), Fasta scores: E(): 0, 100.0% identity in 392 aa overlap. Also highly similar to Mycobacterium tuberculosis probable transferase Rv2739c TR:O33282 (EMBL:AL008967) (388 aa), Fasta scores: E(): 0, 80.9% identity in 388 aa overlap and Erwinia herbicola SW:CRTX_ERWHE (Q01330) (413 aa), Fasta scores: E(): 7.5e-07, 26.1% identity in 410 aa overlap.;UniProt_AC=Q49841;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	843848	845464	.	-	0	Locus=ML0706c;Name=pmmB;Function=;Product=Probable phosphomannomutase PmmB (PHOSPHOMANNOSE MUTASE);Comments=ML0706c, len: 538 aa. Probable pmmB, phosphomannomutase (EC 5.4.2.8), highly similar to O53360|AL123456|Rv3308 pmmB, probable phosphomannomutase from M. tuberculosis (534 aa), Fasta scores: E(): 0, (76.8% identity in 538 aa overlap); and CAD95428|Mb3336 from M. bovis (534 aa). Similar to several e.g. Q9AD82 Putative phosphomannomutase from Streptomyces coelicolor (549 aa), E(): 3e-78, (46.154% identity in 533 aa overlap). Shows weak similarity to ML0366 and ML0763. Previously sequenced as Q49913|U00022 (534 aa), Fasta scores: E(): 0, (99.8% identity in 534 aa overlap). Contains Pfam match to entry PF00408 PGM_PMM, Phosphoglucomutase/phosphomannomutase. Contains PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. BELONGS TO THE PHOSPHOHEXOSE MUTASES FAMILY.;UniProt_AC=Q9CCL7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	700215	703019	.	+	0	Locus=ML0578;Name=ppc;Function=Involved in the Tricarboxylic acid cycle, through THE CARBOXYLATION OF PHOSPHOENOLPYRUVATE (PEP) IT FORMS OXALOACETATE, A FOUR-CARBON DICARBOXYLIC ACID SOURCE FOR THE TRICARBOXYLIC ACID CYCLE [CATALYTIC ACTIVITY : PHOSPHATE + OXALOACETATE = H(2)O + PHOSPHOENOLPYRUVATE + CO(2];Product=Probable phosphoenolpyruvate carboxylase Ppc;Comments=ML0578, len: 934 aa. Probable ppc, phosphoenolpyruvate carboxylase (EC 4.1.1.31), similar to many e.g. CAPP_RHOPA|O32483 ppc, phosphoenolpyruvate carboxylase from Rhodopseudomonas palustris (936 aa), Fasta scores: E(): 5.6e-160, (45.7% identity in 936 aa overlap). Previously sequenced as CAPP_MYCLE|P46710 (907 aa), Fasta scores: E(): 0, (100.0% identity in 907 aa overlap). Contains 2 Pfam matches to entry PF00311 PEPCase, Phosphoenolpyruvate carboxylase. Contains PS00781 Phosphoenolpyruvate carboxylase active site 1. Contains PS00393 Phosphoenolpyruvate carboxylase active site 2. Belongs to the PEPCase family.;UniProt_AC=P46710;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	397946	398677	.	-	0	Locus=ML0311c;Name=psd;Function=;Product=Probable phosphatidylserine decarboxylase Psd;Comments=ML0311c, len: 243 aa. Probable psd, phosphatidylserine decarboxylase (EC 4.1.1.65), highly similar to Rv0437c|O86324|AL123456 psd, possible phosphatidylserine decarboxylase from M. tuberculosis (231 aa), Fasta scores: E(): 0, (72.6% identity in 241 aa overlap). Similar to some other phosphatidylserine decarboxylases e.g. AAF41369|AE002447 phosphatidylserine decarboxylase precursor-related protein from Neisseria meningitidis (265 aa), Fasta scores: E(): 2.5e-23, (39.2% identity in 217 aa overlap); and Q92IU5 Phosphatidylserine decarboxylase from Rickettsia conorii (231 aa). Previously sequenced as Q9ZBM3|AL035159 (202 aa), Fasta scores: E(): 0, (99.5% identity in 202 aa overlap). The start codon is uncertain. Codon usage suggests an alternative start at codon 63 (approx). Contains Pfam match to entry to PF02666 PS_Dcarbxylase, Phosphatidylserine decarboxylase. Belongs to the phosphatidylserine decarboxylases family.;UniProt_AC=Q9CCW9;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	595608	597971	.	+	0	Locus=ML0491;Name=relA;Function=INVOLVED IN THE METABOLISM OF PPGPP (AT THE FIRST STEP). IN EUBACTERIA PPGPP (GUANOSINE 3'-DIPHOSPHATE 5-'DIPHOSPHATE) IS A MEDIATOR OF THE STRINGENT RESPONSE THAT COORDINATES A VARIETY OF CELLULAR ACTIVITIES IN RESPONSE TO CHANGES IN NUTRITIONAL ABUNDANCE. THIS ENZYME CATALYZES THE FORMATION OF PPPGPP WHICH IS THEN HYDROLYSED TO FORM PPGPP [CATALYTIC ACTIVITY: ATP + GTP = AMP + GUANOSINE 3'-DIPHOSPHATE 5-'TRIPHOSPHATE].;Product=PROBABLE GTP PYROPHOSPHOKINASE RELA (ATP:GTP 3'- PYROPHOSPHOTRANSFERASE) (PPGPP SYNTHETASE I) ((P)PPGPP SYNTHETASE) (GTP DIPHOSPHOKINASE);Comments=ML0491, len: 787 aa. Probable relA, GTP pyrophosphokinase (EC 2.7.6.5), highly similar to RELA_MYCTU|Q50638|Rv2583c Probable relA, GTP pyrophosphokinase from M. tuberculosis (790 aa), Fasta scores: E(): 0, (93.4% identity in 790 aa overlap). Also similar to others e.g. O87331|RELA_CORGL|RELA|REL from Corynebacterium glutamicum (Brevibacterium flavum) (760 aa), FASTA scores: E(): 6.1e-209, (66.0% identity in 756 aa overlap). Previously sequenced as RELA_MYCLE|Q49640 (787 aa), Fasta scores: E(): 0, (99.9% identity in 787 aa overlap). Contains a probable helix-turn-helix motif at aa 41-62 (Score 1005, SD +2.61) Contains Pfam match to entry PF01842 ACT, ACT domain. Belongs to the RelA/SpoT family.;UniProt_AC=Q49640;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1118733	1119146	.	-	0	Locus=ML0949c;Name=ML0949c;Function=;Product=Possible regulatory protein (TetR family);Comments=ML0949c, len: 137 aa. Possible regulatory protein, some similarity to other transcription regulator proteins e.g. Q92T19 Putative transcription regulator protein from Rhizobium meliloti (197 aa), fasta scores: E(): 0.04, (35.294% identity in 68 aa overlap). Contains a match to Pfam entry PF00440 Bacterial regulatory proteins, tetR family.;UniProt_AC=Q9CCD1;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	581225	581791	.	+	0	Locus=ML0481;Name=ruvC;Function=NUCLEASE THAT RESOLVES HOLLIDAY JUNCTION INTERMEDIATES IN GENETIC RECOMBINATION. CLEAVES THE CRUCIFORM STRUCTURE IN SUPERCOILED DNA BY NICKING TO STRANDS WITH THE SAME POLARITY AT SITES SYMMETRICALLY OPPOSED AT THE JUNCTION IN THE HOMOLOGOUS ARMS AND LEAVES A 5'TERMINAL PHOSPHATE AND A 3'TERMINAL HYDROXYL GROUP [CATALYTIC ACTIVITY: ENDONUCLEOLYTIC CLEAVAGE AT A JUNCTION SUCH AS A RECIPROCAL SINGLE-STRANDED CROSSOVER BETWEEN TWO HOMOLOGOUS DNA DUPLEXES (HOLLIDAY JUNCTION)].;Product=Probable crossover junction endodeoxyribonuclease RuvC (HOLLIDAY JUNCTION NUCLEASE) (HOLLIDAY JUNCTION RESOLVASE).;Comments=ML0481, len: 188 aa. Probable ruvC, Holliday junction resolvase (EC 3.1.22.4) (see citations below), highly similar to RUVC_MYCTU|Q50627|Rv2594c ruvC, crossover junction endodeoxyribonuclease from M. tuberculosis (188 aa), Fasta scores: E(): 0, (81.5% identity in 184 aa overlap). Also highly similar to others e.g. Q9AE11|RUVC from Corynebacterium glutamicum (Brevibacterium flavum) (221 aa), fasta scores: E(): 9.7e-41, (57.672% identity in 189 aa overlap); and Q9L289|RUVC_STRCO|SCL2.10c from Streptomyces coelicolor (188 aa), fasta scores: E(): 4.2e-39, (64.286% identity in 168 aa overlap). Previously sequenced as RUVC_MYCLE|P40834 (188 aa), Fasta scores: E(): 0, (100.0% identity in 188 aa overlap). Contains Pfam match to entry PF02075 RuvC, Crossover junction endodeoxyribonuclease RuvC. Contains PS01321 Crossover junction endodeoxyribonuclease RuvC signature. Contains PS00572 Glycosyl hydrolases family 1 active site.;UniProt_AC=P40834;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	836930	837391	.	-	0	Locus=ML0699c;Name=sdhC;Function=;Product=Probable succinate dehydrogenase (cytochrome B-556 subunit) SdhC (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE);Comments=ML0699c, len: 153 aa. Probable sdhC, cytochrome B-556 of succinate dehydrogenase SdhC subunit (EC 1.3.99.1), transmembrane protein, highly similar but longer than O53368|AL123456|Rv3316 sdhC, cytochrome B-556 of succinate dehydrogenase from M. tuberculosis (112 aa), Fasta scores: E(): 0, (88.4% identity in 112 aa overlap); and CAD95437|Mb3345 from M. bovis (112 aa). Similar to many e.g. Q9KZ88 Putative succinate dehydrogenase membrane subunit from Streptomyces coelicolor (126 aa), fasta scores: E(): 5.4e-24, (57.273% identity in 110 aa overlap). Previously sequenced as Q49919|U00022 (244 aa), Fasta scores: E(): 0, (100.0% identity in 153 aa overlap). Contains Pfam match to entry PF01127 Sdh_cyt, Succinate dehydrogenase cytochrome b subunit. PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC ANCHOR PROTEIN. BELONGS TO THE CYTOCHROME B560 FAMILY.;UniProt_AC=Q9CCM0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	590037	591830	.	+	0	Locus=ML0487;Name=secD;Function=;Product=Probable protein-export membrane protein SecD;Comments=ML0487, len: 597 aa. Probable secD, protein-export membrane protein (integral membrane protein) (see citation below), highly similar to SECD_MYCTU|Q50634|Rv2587c secD, putative protein-export membrane protein from M. tuberculosis (573 aa), Fasta scores: E(): 3.5e-141, (80.6% identity in 583 aa overlap); and CAD94803|Mb2618c from M. bovis (573 aa). Also similar to others e.g. Q53955|SECD_STRCO from Streptomyces coelicolor (570 aa), FASTA scores: E(): 2.6e-35, (37.655% identity in 563 aa overlap. Previously sequenced as SECD_MYCLE|P38387 (571 aa), Fasta scores: E(): 0, (99.8% identity in 571 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Belongs to the secD/secF family, secD family. Part of the prokaryotic protein translocation apparatus which comprises SecA1|ML0799, SecA2|ML2082c, SecD|ML0487, secG|ML0577,, SecE|ML1907, SecF|ML0488 and SecY|ML1833.;UniProt_AC=P38387;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	769119	771272	.	+	0	Locus=ML0637;Name=uvrD2;Function=INVOLVED IN NUCLEOTIDE EXCISION REPAIR. HAS BOTH ATPASE AND HELICASE ACTIVITIES. UNWINDS DNA DUPLEXES WITH 3' TO 5' POLARITY WITH RESPECT TO THE BOUND STRAND AND INITIATES UNWINDING MOST EFFECTIVELY WHEN A SINGLE-STRANDED REGION IS PRESENT. INVOLVED IN THE POSTINCISION EVENTS OF NUCLEOTIDE EXCISION REPAIR AND METHYL-DIRECTED MISMATCH REPAIR.;Product=Probable ATP-dependent DNA helicase II UvrD2;Comments=ML0637, len: 717 aa. Probable uvrD2, ATP dependent DNA helicase II (EC 3.6.1.-), highly similar to UVRD_MYCTU|O53344|Rv3198c uvrD2, probable ATP-dependent DNA helicase II from M. tuberculosis (700 aa), Fasta scores: E(): 0, (82.9% identity in 706 aa overlap); and CAD95314|Mb3222c (700 aa) from M. bovis. Similar to many e.g. UVRD_ECOLI|P03018 uvrD, DNA helicase II from Escherichia coli (720 aa), Fasta scores: E(): 1.1e-20, (32.6% identity in 660 aa overlap). And similar to ML0153|uvrD1. Previously sequenced as UVRD_MYCLE|P53528 (457 aa), Fasta scores: E(): 0, (100.0% identity in 439 aa overlap). Contains Pfam match to entry PF00570 HRDC, HRDC domain. Contains Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE UVRD SUBFAMILY OF HELICASES.;UniProt_AC=P53528;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1648224	1650959	.	-	0	Locus=ML1381c;Name=polA;Function=;Product=PROBABLE DNA POLYMERASE I POLA;Comments=ML1381c, len: 911 aa. Probable polA, DNA polymerase I (EC 2.7.7.7). Highly similar to DNA polymerase I (EC 2.7.7.7) (PolI) from many bacteria including: Escherichia coli SW:DPO1_ECOLI (P00582) (928 aa), Fasta scores: E(): 0, 36.4% identity in 945 aa overlap and Mycobacterium tuberculosis Rv1629 SW:DPO1_MYCTU (Q07700) (904 aa), Fasta scores: E(): 0, 85.2% identity in 901 aa overlap. Previously sequenced SW:DPO1_MYCLE (P46835) (911 aa), Fasta scores: E(): 0, 99.9% identity in 911 aa overlap. Contains Pfam match to entry PF01367 5_3_exonuclease, 5'-3' exonuclease. Contains Pfam match to entry PF00476 DNA_pol_A, DNA polymerase family A. Contains PS00447 DNA polymerase family A signature.;UniProt_AC=P46835;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	552241	553365	.	-	0	Locus=ML0452c;Name=ML0452c;Function=;Product=Probable alpha-mannosyltransferase PimA;Comments=ML0452c, len: 374 aa. Probable pimA, alpha-mannosyltransferase (EC 2.4.1.-), highly similar to Rv2610c|O06204|AL123456 pimA, alpha-mannosyltransferase from M. tuberculosis   (378 aa), Fasta scores: E(): 0, (82.3% identity in 378 aa overlap). N-terminus is highly similar to Q9FY7 putative alpha-mannosyl transferase (fragment) from Mycobacterium smegmatis (27 aa) (see citation below). Also highly similar to Q9L284|SCL2.15c putative sugar transferase from Streptomyces coelicolor (387 aa), FASTA scores: opt: 1222, E(): 1.8e-67, (52.95% identity in 376 aa overlap); and similar in part to various proteins e.g. Q9R6U1|U45308 sqdX, required for biosynthesis of the sulfolipid sulfoquinovosyldiacylglycerol from Synechococcus sp. (377 aa), Fasta scores: E(): 6.9e-12, (25.9% identity in 390 aa overlap) and to CDS from the Bordetella parapertussis ipopolysaccharide biosynthesis locus e.g. O52848|AJ224768 wlbH, putative glcNac transferase  (390 aa), Fasta scores: E(): 6.1e-12, (27.3% identity in 392 aa overlap). Previously sequenced as O07147|Z96801 (374 aa), Fasta scores: E(): 0, (100.0% identity in 374 aa overlap). Shows weak similarity to ML0886, ML1715 and ML2443 from M. leprae. Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O07147;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1242376	1242738	.	+	0	Locus=ML1079;Name=tatB;Function=;Product=Probable protein TatB;Comments=ML1079, len: 120 aa. Probable TatB, component of twin-arginine translocation protein export system. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49973 (EMBL:U15180) (120 aa), Fasta scores: E(): 0, 98.3% identity in 120 aa overlap. Also highly similar to Mycobacterium tuberculosis TatB protein Rv1224 TR:O33220 (EMBL:Z98260) (131 aa), Fasta scores: E(): 0, (74.0% identity in 131 aa overlap). Also similar, in parts, to Escherichia coli TatB or MttA2, Sec-independent protein translocase, TR:O69415 (EMBL:AJ005830) (171 aa), Fasta scores: E(): 0.00022, 29.8% identity in 121 aa overlap. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CCA4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1276461	1277822	.	-	0	Locus=ML1103c;Name=ML1103c;Function=;Product=PROBABLE OXIDOREDUCTASE;Comments=ML1103c, len: 453 aa. Probable oxidoreductase. Similar to many putative oxidoreductase subunits including: Escherichia coli glycolate oxidase subunit GlcD SW:GLCD_ECOLI (P52075) (499 aa), Fasta scores: E(): 0, 38.8% identity in 456 aa overlap and Mycobacterium tuberculosis probable oxidoreductase Rv1257c TR:Q11061 (EMBL:Z77137) (455 aa), Fasta scores: E(): 0, 85.8% identity in 451 aa overlap. Contains Pfam match to entry PF01565 FAD_binding_4, FAD binding domain.;UniProt_AC=Q9CC92;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1441071	1441751	.	+	0	Locus=ML1218;Name=bioD;Function=;Product=Probable dethiobiotin synthetase BioD;Comments=ML1218, len: 226 aa. Probable bioD, dethiobiotin synthetase (EC 6.3.3.3). Identical to the previously sequenced Mycobacterium leprae dethiobiotin synthetase (EC 6.3.3.3) SW:BIOD_MYCLE (P45486) (223 aa), Fasta scores: E(): 0, 99.6% identity in 223 aa overlap. Also highly similar to several others involved in biotin biosynthesis e.g. Mycobacterium bovis SW:BIOD_MYCBO (O52587) (226 aa), Fasta scores: E(): 0, 74.2% identity in 225 aa overlap and Mycobacterium tuberculosis Rv1570 SW:BIOD_MYCTU (O06620) (226 aa), Fasta scores: E(): 0, 74.2% identity in 225 aa overlap.;UniProt_AC=P45486;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	956157	957890	.	-	0	Locus=ML0808c;Name=entC;Function=COULD BE INVOLVED IN ENTEROBACTIN BIOSYNTHESIS. ENTEROBACTIN IS AN IRON-CHELATING COMPOUND INVOLVED IN TRANSPORTING IRON FROM THE BACTERIAL ENVIRONMENT INTO THE CELL CYTOPLASM. COULD BE ALSO INVOLVED IN 2,3-DIHYDROXYBENZOATE OR ENTEROCHELIN OR MENAQUINONE BIOSYNTHESIS [CATALYTIC ACTIVITY: CHORISMATE = ISOCHORISMATE].;Product=probable isochorismate synthase EntC;Comments=ML0808c, len: 577 aa. Probable entC, isochorismate synthase (EC 5.4.99.6), highly similar to Rv3215|MTCY07D11.11c|O05851|Z95120 entC, isochorismate synthase from Mycobacterium tuberculosis (372 aa), fasta scores: E(): 0, (73.5% identity in 366 aa) and to Bacillus subtilis isochorismate synthase dhbC (398 aa) DHBC_BACSU|P45744 fasta scores: E(): 0, 37.9% identity in 396 aa. Also similar to ML0236 and ML1269 from M. leprae. The predicted CDS has an N-terminal extension of approx. 210 aa not present in known isochorismate synthases. Contains Pfam match to entry PF00425 chorismate_bind, chorismate binding enzyme.;UniProt_AC=Q9CCH5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1064747	1066264	.	-	0	Locus=ML0899c;Name=ML0899c;Function=;Product=Possible conserved integral membrane protein;Comments=ML0899c, len: 505 aa. Possible conserved integral membrane protein. Identical to the previously sequenced Mycobacterium leprae putative integral membrane protein TR:O69566 (EMBL:AL022602) (505 aa), Fasta scores: E(): 0, 100.0% identity in 505 aa overlap. Also highly similar to Mycobacterium tuberculosis putative membrane protein Rv2174 TR:O53508 (EMBL:AL021957) (516 aa), Fasta scores: E(): 0, 78.9% identity in 502 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=O69566;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1183484	1184176	.	-	0	Locus=ML1013c;Name=ideR;Function=TRANSCRIPTIONAL REGULATORY PROTEIN (REPRESSOR AND ACTIVATOR), IRON-BINDING REPRESSOR OF SIDEROPHORE BIOSYNTHESIS AND IRON UPTAKE. SEEMS TO REGULATE A VARIETY OF GENES ENCODING A VARIETY OF PROTEINS e.g. TRANSPORTERS, PROTEINS INVOLVED IN SIDEROPHORE SYNTHESIS AND IRON STORAGE, MEMBERS OF THE PE/PPE FAMILY, ENZYMES INVOLVED IN LIPID METABOLISM, TRANSCRIPTIONAL REGULATORY PROTEINS, ETC. ALSO ACTIVATOR OF BFRA GENE.;Product=IRON-DEPENDENT REPRESSOR AND ACTIVATOR IDER;Comments=ML1013c, len: 230 aa. Probable ideR, iron dependent repressor and activator. Highly similar to  multiple iron-binding regulatory proteins such as Mycobacterium tuberculosis Rv2711 SW:IDER_MYCTU (Q50495) (230 aa), Fasta scores: E(): 0, 90.0% identity in 230 aa overlap and Corynebacterium diphtheriae SW:DTXR_CORDI (P33120) (226 aa), Fasta scores: E(): 0, 56.1% identity in 230 aa overlap. Contains Pfam match to entry PF01325 Fe_dep_repress, Iron dependent repressor.;UniProt_AC=Q9CCB5;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	965933	967120	.	+	0	Locus=ML0817;Name=moeB1;Function=;Product=PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE);Comments=ML0817, len: 395 aa. Probable moeB1, molybdopterin cofactor biosynthesis protein. Similar to Rv3206c|O05860|AL123456 M. tuberculosis moeB homologue (392 aa), Fasta scores: E(): 0, 86.4% identity in 391 aa overlap and to Rv3116|O05792|AL123456 M. tuberculosis moeB2 putative molybdopterin biosynthesis protein  (389 aa), Fasta scores: E(): 0, 57.8% identity in 384 aa overlap. Similar to many e.g. Q9ZNW0|AF124160 Arabidopsis thaliana cnx5, molybdopterin synthase sulphurylase, (464 aa), Fasta scores: E(): 0, 34.5% identity in 406 aa overlap. Contains Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain. Contains Pfam match to entry PF00899 ThiF_family, ThiF family. BELONGS TO THE HesA /MoeB/ThiF FAMILY;UniProt_AC=Q9CCG8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	988461	990389	.	+	0	Locus=ML0833;Name=dnaG;Function=;Product=PROBABLE DNA PRIMASE DNAG;Comments=ML0833, len: 642 aa. Probable dnaG, DNA primase (EC 2.7.7.-). Similar to Rv2343c|PRIM_MYCTU|P95239 Mycobacterium tuberculosis DNA primase (639 aa) fasta scores: E(): 0, 80.4% identity in 642 aa, and to O52200|AF027507 Mycobacterium smegmatis primase dnaG (636 aa) fasta scores: E(): 0, 76.2% id in 642 aa. Contains Pfam match to entry PF01751 Toprim, Toprim domain. Contains Pfam match to entry PF01807 zf-CHC2, CHC2 zinc finger.;UniProt_AC=Q9CCG2;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1002562	1004115	.	+	0	Locus=ML0844;Name=narK;Function=;Product=PROBABLE NITRITE EXTRUSION PROTEIN 1 NARK (NITRITE FACILITATOR 1);Comments=ML0844, len: 517 aa. Probable narK, nitrite extrusion protein, possibly member of major facilitator superfamily (MFS).  Similar to Mycobacterium tuberculosis putative nitrite extrusion protein narK1 or Rv2329c or MTCY3G12.05 TR:P71883 (EMBL:Z79702) (515 aa) fasta scores: E(): 0, 69.3% identity in 488 aa and to Escherichia coli nitrite extrusion protein 2 narU SW:NARU_ECOLI (P37758; P77696) (462 aa) fasta scores: E(): 0, 36.6% identity in 459 aa. There is a frameshift near the C-terminus relative to the M. tuberculosis homologue. Previously sequenced as TR:O32974 (EMBL:Z98741). Contains hydrophobic, probable membrane-spanning regions. BELONGS TO THE NARK/NASA FAMILY OF TRANSPORTERS.;UniProt_AC=O32974;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1019693	1020445	.	-	0	Locus=ML0857c;Name=ML0857c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML0857c, len: 250 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rv2219 or MTCY190.30 SW:YM19_MYCTU (Q10405) (250 aa) fasta scores: E(): 0, 80.8% identity in 250 aa. Similar to Streptomyces coelicolor putative integral membrane protein SC3H12.04 TR:CAB90843 (EMBL:AL355740) (234 aa) fasta scores: E(): 1.2e-26, 39.6% identity in 230 aa and to Streptomyces coelicolor putative integral membrane protein SC5F7.05 TR:Q9S2P0 (EMBL:AL096872) (234 aa) fasta scores: E(): 1.2e-26, 39.6% identity in 230 aa. Previously sequenced as TR:O32963 (EMBL:Z98741). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=O32963;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1250667	1251530	.	+	0	Locus=ML1088;Name=sugB;Function=;Product=PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGB;Comments=ML1088, len: 287 aa. Probable sugB, sugar-transport integral membrane protein ABC transporter. Previously sequenced Mycobacterium leprae MalG TR:Q49977 (EMBL:U15180) (296 aa), Fasta scores: E(): 0, 100.0% identity in 287 aa overlap. Also highly similar to many putative membrane transport proteins including: Mycobacterium tuberculosis probable sugar transport protein Rv1237 TR:O50453 (EMBL:AL021006) (274 aa), Fasta scores: E(): 0, 89.4% identity in 274 aa overlap and Thermococcus litoralis inner membrane protein MalG TR:O51925 (EMBL:AF012836) (278 aa), Fasta scores: E(): 4.1e-31, 35.9% identity in 270 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component.;UniProt_AC=Q9CCA1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1012138	1013133	.	+	0	Locus=ML0852;Name=ribF;Function=;Product=PROBABLE BIFUNCTIONAL FAD SYNTHETASE/RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF: RIBOFLAVIN KINASE (FLAVOKINASE) + FMN ADENYLYLTRANSFERASE (FAD PYROPHOSPHORYLASE) (FAD SYNTHETASE)(FAD DIPHOSPHORYLASE) (FLAVIN ADENINE DINUCLEOTIDE SYNTHETASE);Comments=ML0852, len: 331 aa. Probable ribF, FAD synthetase/riboflavin biosynthesis protein, bifunctional enzyme (EC 2.7.1.26. Similar to Mycobacterium tuberculosis riboflavin kinase ribF or Rv2786c or MTV002.51C TR:O33328 (EMBL:AL008967) (331 aa) fasta scores: E(): 0, 87.5% identity in 327 aa and to many others e.g. Corynebacterium ammoniagenes riboflavin biosynthesis protein RibF (includes riboflavin kinase) ribF SW:RIBF_CORAM (Q59263) (338 aa) fasta scores: E(): 0, 47.7% identity in 321 aa. Previously sequenced as TR:O32968 (EMBL:Z98741). Contains Pfam match to entry PF01687 FAD_Synth, Riboflavin kinase / FAD synthetase.;UniProt_AC=O32968;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2028724	2029326	.	-	0	Locus=ML1683c;Name=hupB;Function=;Product=PROBABLE DNA-BINDING PROTEIN HU HOMOLOG HUPB (HISTONE-LIKE PROTEIN) (HLP) (21-KDA LAMININ-2-BINDING PROTEIN);Comments=ML1683c, len: 200 aa. Probable hupB, DNA-binding protein HU homolog. Highly similar to Mycobacterial histone-like proteins e.g. Mycobacterium smegmatis TR:Q9ZHC5 (EMBL:AF068138) (269 aa), BlastP Expect 0.0014 and Mycobacterium tuberculosis Rv2986c SW:DBH_MYCTU (P95109) (214 aa), Fasta scores: E(): 0, 80.1% identity in 216 aa overlap. Also similar to many bacterial histone-like DNA-binding proteins e.g. Bacillus stearothermophilus SW:DBH_BACST (P02346) (90 aa), Fasta scores: E(): 2e-09, 48.3% identity in 89 aa overlap. Note that the C-terminus is rich in the amino acids Ala, Val and Lys. Contains Pfam match to entry PF00216 Bac_DNA_binding, Bacterial DNA-binding protein. Contains PS00045 Bacterial histone-like DNA-binding proteins signature.;UniProt_AC=O33125;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1027289	1028863	.	-	0	Locus=ML0864c;Name=pepB;Function=;Product=Probable cytosol aminopeptidase PepB;Comments=ML0864c, len: 524 aa. Probable pepB, cytosol aminopeptidase (EC 3.4.11.1). Similar to Mycobacterium tuberculosis probable cytosol aminopeptidase pepA or pepB or Rv2213 or MTCY190.24 SW:AMPA_MYCTU (Q10401) (515 aa) fasta scores: E(): 0, 83.0% identity in 522 aa. Similar to many e.g. Rickettsia prowazekii cytosol aminopeptidase pepA or rp142 SW:AMPA_RICPR (P27888) (500 aa) fasta scores: E(): 0, 39.1% identity in 384 aa. Previously sequenced as TR:O32956 (EMBL:Z98741). Contains Pfam match to entry PF00883 Peptidase_M17, Cytosol aminopeptidase family. Contains PS00631 Cytosol aminopeptidase signature. Belongs to peptidase family M17.;UniProt_AC=O32956;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1029024	1030127	.	+	0	Locus=ML0865;Name=gcvT;Function=;Product=Probable aminomethyltransferase GcvT (Glycine cleavage system T protein);Comments=ML0865, len: 367 aa. Probable gcvT, aminomethyltransferase (EC 2.1.2.10). Similar to Mycobacterium tuberculosis probable aminomethyltransferase gcvT or Rv2211c or MTCY190.22 SW:GCST_MYCTU (Q10376) (379 aa) fasta scores: E(): 0, 84.7% identity in 367 aa. Similar to many e.g. Escherichia coli aminomethyltransferase gcvT SW:GCST_ECOLI (P27248) (363 aa) fasta scores: E(): 0, 39.0% identity in 364 aa. Previously sequenced as TR:O32955 (EMBL:Z98741). Contains Pfam match to entry PF01571 GCV_T, Glycine cleavage T-protein (aminomethyl transferase). Belongs to the gcvT family.;UniProt_AC=O32955;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1037609	1039642	.	-	0	Locus=ML0874c;Name=asnB;Function=;Product=Probable asparagine synthetase [glutamine-hydrolyzing] AsnB;Comments=ML0874c, len: 677 aa.  Probable asnB, asparagine synthetase (EC 6.3.5.4). Similar to Mycobacterium tuberculosis putative asparagine synthetase [glutamine-hydrolyzing] Rv2201 or mtcy190.12 SW:ASNH_MYCTU (Q10374) (652 aa) fasta scores: E(): 0, 83.3% identity in 659 aa and to Bacillus subtilis asparagine synthetase [glutamine-hydrolyzing] 1 asnB or asn SW:ASNB_BACSU (P54420; O34902) (632 aa) fasta scores: E(): 0, 49.0% id in 614 aa. Contains Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II. Contains Pfam match to entry PF00733 Asn_synthase, Asparagine synthase.;UniProt_AC=Q9CCF2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1044810	1045994	.	-	0	Locus=ML0880c;Name=qcrA;Function=;Product=Probable Rieske iron-sulfur protein QcrA (Ubiquinol-cytochrome C reductase iron-sulfur subunit);Comments=ML0880c, len: 394 aa. Probable qcrA, Rieske iron-sulfur protein. Similar to Mycobacterium tuberculosis putative ubiquinol-cytochrome C reductase iron-sulfur subunit qcrA or Rv2195 or MTCY190.06 SW:QCRA_MYCTU (Q10387) (429 aa) fasta scores: E(): 0, 80.9% identity in 398 aa. Contains hydrophobic, probable membrane-spanning regions. Contains PS00200 Rieske iron-sulfur protein signature 2. THE MAIN SUBUNITS OF THE UBIQUINOL:CYTOCHROME C COMPLEX ARE: CYTOCHROME B, THE RIESKE PROTEIN AND A CYTOCHROME C SUBUNIT.;UniProt_AC=Q9CCE7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1519744	1521162	.	+	0	Locus=ML1277;Name=pykA;Function=;Product=Probable pyruvate kinase PykA;Comments=ML1277, len: 472 aa. Probable pyruvate kinase (EC 2.7.1.40). Highly similar to many pyruvate kinases including: Mycobacterium tuberculosis Rv1617 SW:KPYK_MYCTU (O06134) (472 aa), Fasta scores: E(): 0, 90.7% identity in 472 aa overlap and Corynebacterium glutamicum SW:KPYK_CORGL (Q46078) (475 aa), Fasta scores: E(): 0, 71.8% identity in 468 aa overlap. Contains Pfam match to entry PF00224 PK, Pyruvate kinase. Contains PS00110 Pyruvate kinase active site signature.;UniProt_AC=Q9CC49;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1043158	1044813	.	-	0	Locus=ML0879c;Name=qcrB;Function=;Product=Probable Ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit);Comments=ML0879c, len: 551 aa. Probable qcrB, Ubiquinol-cytochrome C reductase cytochrome B subunit (cytB), integral membrane protein. Similar to Mycobacterium tuberculosis ubiquinol-cytochrome C reductase cytochrome B subunit qcrB or Rv2196 or MTCY190.07 SW:QCRB_MYCTU (Q10388) (549 aa) fasta scores: E(): 0, 92.5% identity in 548 aa and to Streptomyces lividans ubiquinol-cytochrome C reductase cytochrome b subunit qcrB SW:QCRB_STRLI (Q9ZFB6) (549 aa) fasta scores: E(): 0, 44.8% identity in 533 aa. N-terminal half is similar to some cytochomes e.g. Bacillus stearothermophilus menaquinol-cytochrome C reductase cytochrome B subunit qcrB SW:QCRB_BACST (Q45658) (224 aa) fasta scores: E(): 1.1e-13, 27.1% identity in 207 aa. Contains hydrophobic, probable membrane-spanning regions. Contains Pfam match to entry PF00033 cytochrome_b_N, Cytochrome b(N-terminal)/b6/petB. BELONGS TO THE CYTOCHROME B FAMILY. CORRESPONDS TO THE AMINO END OF MITOCHONDRIAL CYTOCHROME B. ;UniProt_AC=P15878;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1052135	1053289	.	+	0	Locus=ML0886;Name=ML0886;Function=;Product=possible glycosyl transferase.;Comments=ML0886, len: 384 aa. Possible glycosyl transferase. Similar to Mycobacterium tuberculosis hypothetical protein TR:O53522 (EMBL:AL021957) (385 aa), Fasta scores: E(): 0, 81.5% identity in 383 aa overlap and several Streptomyces coelicolor putative glycosyl transferases e.g. TR:Q9X7Z1 (EMBL:AL049497) (412 aa), Fasta scores: E(): 0, 52.2% identity in 387 aa overlap(EMBL:AL049497). Previously sequenced Mycobacterium leprae hypothetical protein TR:O69579 (EMBL:AL022602) (384 aa), Fasta scores: E(): 0, 99.7% identity in 384 aa overlap(EMBL:AL022602).Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1.;UniProt_AC=O69579;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1071590	1072708	.	+	0	Locus=ML0906;Name=ML0906;Function=;Product=conserved hypothetical protein;Comments=ML0906, len: 372 aa. Conserved hypothetical protein. Identical over 340 aa to the previously sequenced Mycobacterium leprae hypothetical protein SW:YL65_MYCLE (SW:O69560) (340 aa), Fasta scores: E(): 0, 99.7% identity in 340 aa overlap. Also highly similar to many other proteins of undefined function including: Mycobacterium tuberculosis Rv2165c TR:O06212 (EMBL:Z95388) (396 aa), Fasta scores: E(): 0, 74.2% identity in 376 aa overlap and Escherichia coli SW:YABC_ECOLI (SW:P18595) (313 aa), Fasta scores: E(): 0, 41.6% identity in 298 aa overlap. Contains Pfam match to entry PF01795 DUF36, Domain of unknown function.;UniProt_AC=O69560;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1076004	1077596	.	+	0	Locus=ML0909;Name=murE;Function=;Product=ProbableUDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE;Comments=ML0909, len: 530 aa. Probable murE, UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase (EC 6.3.2.13). Identical to the previously sequenced Mycobacterium leprae UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) SW:MURE_MYCLE (AL022602) (530 aa), Fasta scores: E(): 0, 99.8% identity in 530 aa overlap. Also highly similar to MurE orthologues from Mycobacterium tuberculosis SW:MURE_MYCTU (O06219) (535 aa), Fasta scores: E(): 0, 74.4% identity in 519 aa overlap and Escherichia coli SW:MURE_ECOLI (P22188) (494 aa), Fasta scores: E(): 0, 39.1% identity in 493 aa overlap. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family. Belongs to the murCDEF family. ;UniProt_AC=O69557;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1073835	1075862	.	+	0	Locus=ML0908;Name=pbpB;Function=;Product=Probable penicillin-binding membrane protein PbpB;Comments=ML0908, len: 675 aa. Probable pbpB, penicillin-binding membrane protein. Identical to the previously sequenced Mycobacterium leprae penicillin binding protein 2 TR:O69558 (EMBL:AL022602) (675 aa), Fasta scores: E(): 0, 99.9% identity in 675 aa overlap(EMBL:AL022602). Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2163c TR:O06214 (EMBL:Z95388) (679 aa), Fasta scores: E(): 0, 80.6% identity in 677 aa overlap(EMBL:Z95388) and to many other penicillin-binding proteins e.g. Neisseria meningitidis SW:PBP2_NEIME (P11882) (581 aa), Fasta scores: E(): 4.3e-29, 32.4% identity in 590 aa overlap(P11882). Contains Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O69558;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2232818	2233159	.	-	0	Locus=ML1849c;Name=rplN;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L14 RPLN;Comments=ML1849c, len: 113 aa. Probable rplN,50S ribosomal protein L14.  Similar to M. tuberculosis 50S ribosomal protein L14 Rv0714 SW:RL14_MYCTU (P95062) (122 aa), Fasta scores: E(): 0, 96.5% identity in 113 aa overlap. Contains Pfam match to entry PF00238 Ribosomal_L14, Ribosomal protein L14p/L23e. Contains PS00049 Ribosomal protein L14 signature.;UniProt_AC=O32993;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1084524	1086011	.	+	0	Locus=ML0915;Name=murC;Function=;Product=Probable UDP-N-acetylmuramate-alanine ligase MurC;Comments=ML0915, len: 495 aa. Probable murC, UDP-N-acetylmuramate-alanine ligase (EC 6.3.2.8). Identical, over available sequence, to the previously sequenced Mycobacterium leprae UDP-N-acetylmuramate-alanine ligase (fragment) TR:O69551 (EMBL:AL022602) (235 aa), Fasta scores: E(): 0, 99.6% identity in 235 aa overlap. Also highly similar to UDP-N-acetylmuramate-alanine ligases from Mycobacterium tuberculosis SW:MURC_MYCTU (SW:O06225) (494 aa), Fasta scores: E(): 0, 79.8% identity in 494 aa overlap and Escherichia coli SW:MURC_ECOLI (SW:P17952) (491 aa), Fasta scores: E(): 0, 35.2% identity in 477 aa overlap. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family. Belongs to the murCDEF family. ;UniProt_AC=P57994;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1091351	1092151	.	+	0	Locus=ML0922;Name=wag31;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN WAG31;Comments=ML0922, len: 266 aa. Probable wag31, conserved hypothetical protein. Identical to the previously sequenced and characterised Mycobacterium leprae antigen 84 SW:AG84_MYCLE (P46815) (266 aa), Fasta scores: E(): 0, 100.0% identity in 266 aa overlap. Also highly similar to Mycobacterium tuberculosis Rv2145c SW:AG84_MYCTU (P46816) (260 aa), Fasta scores: E(): 0, 83.1% identity in 266 aa overlap. Similar to ML2253c from M. leprae. Contains several possible coiled-coil regions. Note previously known as ag84.;UniProt_AC=P46815;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1124870	1125379	.	+	0	Locus=ML0956;Name=ML0956;Function=;Product=Putative integral membrane protein.;Comments=ML0956, len: 169 aa. Putative integral membrane protein. Similar to Q9RKN9|AL133220 Streptomyces coelicolor putative membrane protein  (180 aa), Fasta scores: E(): 2.8e-13, (43.8% identity in 137 aa overlap). Almost identical to the previously sequenced O05565|Z94723 Mycobacterium leprae hypothetical protein (214 aa), Fasta scores: E(): 0, 100.0% identity in 169 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains a Pfam match to entry PF04173 DoxD-like family.;UniProt_AC=Q9CCC8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1231780	1232007	.	+	0	Locus=ML1067;Name=ML1067;Function=;Product=conserved hypothetical protein;Comments=ML1067, len: 75 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49958 (EMBL:U15180) (75 aa), Fasta scores: E(): 1.9e-29, 100.0% identity in 75 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1211 TR:O05312 (EMBL:Z93777) (75 aa), Fasta scores: E(): 1.6e-26, 90.7% identity in 75 aa overlap.;UniProt_AC=Q49958;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1127780	1130062	.	-	0	Locus=ML0961c;Name=metE;Function=CATALYZES THE TRANSFER OF A METHYL GROUP FROM 5-METHYLTETRAHYDROFOLATE TO HOMOCYSTEINE RESULTING IN METHIONINE FORMATION (PATHWAY: TERMINAL STEP IN THE DE NOVO BIOSYNTHESIS OF METHIONINE) [CATALYTIC ACTIVITY : 5-METHYLTETRAHYDROPTEROYLTRI-L-GLUTAMATE  + L- HOMOCYSTEINE = TETRAHYDROPTEROYLTRI-L-GLUTAMATE + L-METHIONINE.];Product=PROBABLE5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE METE (methionine synthase, vitamin-B12 independent isozyme);Comments=ML0961c, len: 760 aa. Probable metE, 5-methyltetrahydropteroyltriglutamate-homocystein methyltransferase (EC 2.1.1.14). Identical to the previously sequenced Mycobacterium leprae 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) SW:METE_MYCLE (O05564) (760 aa), Fasta scores: E(): 0, 100.0% identity in 760 aa overlap. Also highly similar to MetE orthologues from Mycobacterium tuberculosis Rv1133c SW:METE_MYCTU (O06584) (759 aa), Fasta scores: E(): 0, 85.0% identity in 759 aa overlap and Escherichia coli SW:METE_ECOLI (P25665) (752 aa), Fasta scores: E(): 0, 47.5% identity in 754 aa overlap. Contains Pfam match to entry PF01717 Methionine_synt, Methionine synthase, vitamin-B12 independent. BELONGS TO THE VITAMIN-B12 INDEPENDENT METHIONINE SYNTHASE FAMILY.;UniProt_AC=O05564;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1152705	1152908	.	+	0	Locus=ML0986;Name=ML0986;Function=;Product=conserved hypothetical protein;Comments=ML0986, len: 67 aa. Conserved hypothetical protein. Highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv2738c TR:O33281 (EMBL:AL008967) (68 aa), Fasta scores: E(): 7.9e-24, 85.1% identity in 67 aa overlap and Streptomyces coelicolor TR:O50484 (EMBL:AL020958) (64 aa), Fasta scores: E(): 2.5e-08, 44.4% identity in 63 aa overlap.;UniProt_AC=Q9CCC1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1157284	1157913	.	+	0	Locus=ML0990;Name=ML0990;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML0990, len: 209 aa. Probable conserved transmembrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49834 (EMBL:U00019) (209 aa), Fasta scores: E(): 0, 100.0% identity in 209 aa overlap. Also highly similar to Mycobacterium tuberculosis Rv2732c TR:O33237 (EMBL:Z98209) (204 aa), Fasta scores: E(): 0, 70.6% identity in 201 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q49834;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1153059	1155194	.	+	0	Locus=ML0987;Name=recA;Function=INVOLVED IN REGULATION OF NUCLEOTIDE EXCISION REPAIR, IN GENETIC RECOMBINATION, AND IN INDUCTION OF THE SOS RESPONSE. ENDONUCLEASE WHICH CAN CATALYZE THE HYDROLYSIS OF ATP IN THE PRESENCE OF SINGLE-STRANDED DNA, THE ATP-DEPENDENT UPTAKE OF SINGLE-STRANDED DNA BY DUPLEX DNA, AND THE ATP-DEPENDENT HYBRIDIZATION OF HOMOLOGOUS SINGLE-STRANDED DNAS. IT INTERACTS WITH LEXA CAUSING ITS ACTIVATION AND LEADING TO ITS AUTOCATALYTIC CLEAVAGE.;Product=RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN].;Comments=ML0987, len: 711 aa. Probable RecA protein (EC 3.1.-.-). Identical to the previously sequenced and characterised Mycobacterium leprae RecA protein involved in DNA recombination and the SOS response SW:RECA_MYCLE (P35901) (711 aa), Fasta scores: E(): 0, 100.0% identity in 711 aa overlap. Also highly similar to many others e.g. Mycobacterium tuberculosis Rv2737c SW:RECA_MYCTU (P26345) (790 aa), Fasta scores: E(): 0, 46.7% identity in 814 aa overlap. Note the Mycobacterium leprae RecA protein is known to possess an intron which is self-spliced at the post-translational level. Contains 2 Pfam matches to entry PF00154 recA, recA bacterial DNA recombination proteins. Contains PS00321 recA signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00881 Protein splicing signature. Belongs to the recA family. ;UniProt_AC=P35901;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1172922	1174985	.	+	0	Locus=ML1002;Name=ML1002;Function=;Product=Possible conserved transmembrane protein;Comments=ML1002, len: 687 aa. Possible conserved transmembrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49837 (EMBL:U00019) (687 aa), Fasta scores: E(): 0, 99.9% identity in 687 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2721c TR:O07219. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q49837;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1176011	1176505	.	+	0	Locus=ML1004;Name=ML1004;Function=;Product=possible conserved membrane protein;Comments=ML1004, len: 164 aa. Possible conserved membrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49846 (EMBL:U00019) (164 aa), Fasta scores: E(): 0, 100.0% identity in 164 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2719c TR:O07218 (EMBL:Z96072) (165 aa), Fasta scores: E(): 1.8e-23, 55.2% identity in 163 aa overlap. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q49846;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1176667	1177131	.	+	0	Locus=ML1005;Name=ML1005;Function=;Product=conserved hypothetical protein;Comments=ML1005, len: 154 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49844 (EMBL:U00019) (154 aa), Fasta scores: E(): 0, 100.0% identity in 154 aa overlap. Also highly similar to a number of other proteins of unknown function e.g. Mycobacterium tuberculosis Rv2718c TR:O07217 (EMBL:Z96072) (154 aa), Fasta scores: E(): 0, 92.7% identity in 151 aa overlap and Escherichia coli SW:YBAD_ECOLI (P25538) (149 aa), Fasta scores: E(): 9.7e-21, 45.6% identity in 147 aa overlap. Belongs to the UPF0168 family. ;UniProt_AC=Q49844;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1191846	1192721	.	+	0	Locus=ML1024;Name=suhB;Function=;Product=possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ).;Comments=ML1024, len: 291 aa. Possible subH, inositol monophosphatase. Identical to the previously sequenced Mycobacterium leprae extragenic suppressor protein SuhB homologue SW:SUHB_MYCLE (P46813) (291 aa), Fasta scores: E(): 0, 99.7% identity in 291 aa overlap. Also highly similar to many other members of the inositol monophosphatase family including: Mycobacterium tuberculosis, Rv2701c SW:SUHB_MYCTU (O07203) (290 aa), Fasta scores: E(): 0, 77.6% identity in 294 aa overlap and Escherichia coli ShuB, SW:SUHB_ECOLI (P22783) (267 aa), Fasta scores: E(): 1.6e-18, 34.7% identity in 239 aa overlap, shown to suppress the effect of a temperature-sensitive mutation in E. coli. Note the predicted translational start site for this CDS maybe incorrect due to the overlap with CDS ML1023. Contains Pfam match to entry PF00459 inositol_P, Inositol monophosphatase family. Contains PS00629 Inositol monophosphatase family signature 1. Contains PS00630 Inositol monophosphatase family signature 2. Belongs to the inositol monophosphatase family. ;UniProt_AC=P46813;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1194377	1194841	.	+	0	Locus=ML1028;Name=dut;Function=INVOLVED IN BIOSYNTHESIS OF THYMIDYLATE. THIS ENZYME IS INVOLVED IN NUCLEOTIDE METABOLISM: IT PRODUCES DUMP, THE IMMEDIATE PRECURSOR OF THYMIDINE NUCLEOTIDES AND IT DECREASES THE INTRACELLULAR CONCENTRATION OF DUTP SO THAT URACIL CANNOT BE INCORPORATED INTO DNA [CATALYTIC ACTIVITY: DUTP + H(2)O = DUMP + PYROPHOSPHATE].;Product=PROBABLE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DUT (DUTPASE) (DUTP PYROPHOSPHATASE) (DEOXYURIDINE 5'-TRIPHOSPHATASE) (DUTP DIPHOSPHATASE) (DEOXYURIDINE-TRIPHOSPHATASE);Comments=ML1028, len: 154 aa. Probable dut, deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23). Identical to the previously sequenced Mycobacterium leprae deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23) SW:DUT_MYCLE (Q49992) (155 aa), Fasta scores: E(): 0, 100.0% identity in 154 aa overlap. Also highly similar to many other dUTPases, involved in nucleotide metabolism, including Mycobacterium tuberculosis SW:DUT_MYCTU (O07199) (154 aa), Fasta scores: E(): 0, 90.3% identity in 154 aa overlap and Escherichia coli SW:DUT_ECOLI (P06968) (461 aa), BlastP Expect 8.8. Contains Pfam match to entry PF00692 dUTPase, dUTPase. BELONGS TO THE DUTPASE FAMILY. ;UniProt_AC=Q49992;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1208220	1209293	.	+	0	Locus=ML1043;Name=hemE;Function=;Product=PROBABLE UROPORPHYRINOGEN DECARBOXYLASE HEME (UROPORPHYRINOGEN III DECARBOXYLASE) (URO-D) (UPD);Comments=ML1043, len: 357 aa. Probable hemE, uroporphyrinogen decarboxylase (EC 4.1.1.37). Identical to the previously sequenced Mycobacterium leprae uroporphyrinogen decarboxylase (EC 4.1.1.37) SW:DCUP_MYCLE (P46809) (357 aa), Fasta scores: E(): 0, 100.0% identity in 357 aa overlap. Also highly similar to many others including: Mycobacterium tuberculosis SW:DCUP_MYCTU (O53231) (357 aa), Fasta scores: E(): 0, 83.8% identity in 357 aa overlap and Bacillus subtilis SW:DCUP_BACSU (P32395) (353 aa), Fasta scores: E(): 0, 43.5% identity in 354 aa overlap. Contains Pfam match to entry PF01208 URO-D, Uroporphyrinogen decarboxylase (URO-D). Contains PS00907 Uroporphyrinogen decarboxylase signature 2. Contains PS00906 Uroporphyrinogen decarboxylase signature 1. Belongs to the uroporphyrinogen decarboxylase family.;UniProt_AC=P46809;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1210651	1211346	.	+	0	Locus=ML1045;Name=ML1045;Function=;Product=conserved hypothetical protein;Comments=ML1045, len: 696 aa. Conserved hypothetical protein. Identical, apart from N-terminus, to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q50009 (EMBL:U15181) (297 aa), Fasta scores: E(): 0, 100.0% identity in 231 aa overlap. Also highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv2676c TR:P71973 (EMBL:Z80225) (231 aa), Fasta scores: E(): 0, 87.4% identity in 231 aa overlap and Streptomyces coelicolor TR:O69830 (EMBL:AL023517) (243 aa), Fasta scores: E(): 0, 61.3% identity in 222 aa overlap.;UniProt_AC=Q9CCB2;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1218565	1219830	.	-	0	Locus=ML1052c;Name=ML1052c;Function=;Product=conserved hypothetical protein;Comments=ML1052c, len: 421 aa. Conserved hypothetical protein. Previously sequenced Mycobacterium leprae hypothetical protein TR:Q50018 (EMBL:U15181) (517 aa), Fasta scores: E(): 0, 100.0% identity in 421 aa overlap. Also highly similar to several hypothetical proteins from Mycobacterium tuberculosis e.g. Rv1194c TR:O05296 (EMBL:Z93777) (421 aa), Fasta scores: E(): 0, 70.1% identity in 421 aa overlap.;UniProt_AC=Q9CCB1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1230988	1231566	.	+	0	Locus=ML1066;Name=tagA;Function=;Product=PROBABLE DNA-3-METHYLADENINE GLYCOSYLASE I TAGA (TAG I) (3-methyladenine-DNA glycosylase I, constitutive) (DNA-3-methyladenine glycosidase I );Comments=ML1066, len: 192 aa. Probable tagA, DNA-3-methyladenine glycosidase I (EC 3.2.2.20). Identical to the previously sequenced Mycobacterium leprae TR:Q49957 (EMBL:U15180) (192 aa), Fasta scores: E(): 0, 99.5% identity in 192 aa overlap. Also highly similar to DNA-3-methyladenine glycosidases from  Mycobacterium tuberculosis Rv1210 TR:O05311 (EMBL:Z93777) (204 aa), Fasta scores: E(): 0, 80.2% identity in 192 aa overlap and Escherichia coli SW:3MG1_ECOLI (P05100) (187 aa), Fasta scores: E(): 1.8e-27, 43.8% identity in 185 aa overlap.;UniProt_AC=Q49957;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1239343	1240134	.	+	0	Locus=ML1076;Name=sigE;Function=;Product=ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGE;Comments=ML1076, len: 263 aa. sigE, alternative sigma factor of extracytoplasmic function (ECF) family. Highly similar to many proposed ECF-family RNA-polymerase sigma factors including: Mycobacterium tuberculosis SigE Rv1221 TR:O06289 (EMBL:U87242) (257 aa), Fasta scores: E(): 0, 82.1% identity in 252 aa overlap, Mycobacterium avium SigE TR:O05735 (EMBL:U87308) (251 aa), Fasta scores: E(): 0, 80.6% identity in 247 aa overlap and Bacillus subtilis SW:SIGW_BACSU (Q45585) (187 aa), Fasta scores: E(): 2.9e-16, 35.7% identity in 171 aa overlap. Contains a possible helix-turn-helix motif situated between residues 213..234 (+3.09 SD). Contains a probable helix-turn-helix motif at aa 213-234 (Score 1147, SD +3.09) Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). BELONGS TO THE SIGMA-70 FACTOR FAMILY, ECF SUBFAMILY.;UniProt_AC=Q9CCA6;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1253342	1254451	.	-	0	Locus=ML1090c;Name=corA;Function=;Product=POSSIBLE MAGNESIUM AND COBALT TRANSPORT TRANSMEMBRANE PROTEIN CORA;Comments=ML1090c, len: 369 aa. Possible corA, magnesium and cobalt transport transmembrane protein. Previously sequenced Mycobacterium leprae TR:Q49979 (EMBL:U15180) (373 aa), Fasta scores: E(): 0, 100.0% identity in 369 aa overlap. Highly similar to Mycobacterium tuberculosis magnesium and cobalt transport protein, CorA (Rv1239c) TR:O50455 (EMBL:AL021006) (366 aa), Fasta scores: E(): 0, 79.4% identity in 369 aa overlap. Also weakly similar to Haemophilus influenzae SW:CORA_HAEIN (P44998) (315 aa), Fasta scores: E(): 2.8e-07, 24.1% identity in 323 aa overlap, CorA transporter. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01544 CorA, CorA-like Mg2+ transporter protein.;UniProt_AC=Q9CCA0;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1272635	1273774	.	+	0	Locus=ML1101;Name=ML1101;Function=;Product=PROBABLE ACYLTRANSFERASE;Comments=ML1101, len: 379 aa. Probable acyltransferase (EC 2.3.1.-). Similar to several acyltransferases including: Streptomyces thermotolerans macrolide antibiotics 3-O-acyltransferase TR:Q56074 (EMBLD30759:) (389 aa), Fasta scores: E(): 1.3e-14, 29.4% identity in 377 aa overlap and Mycobacterium tuberculosis probable acyltransferase Rv1254 TR:Q11064 (EMBL:Z77137) (383 aa), Fasta scores: E(): 0, 79.6% identity in 378 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CC93;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1289626	1291380	.	-	0	Locus=ML1114c;Name=ML1114c;Function=;Product=PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER;Comments=ML1114c, len: 584 aa. Probable drugs-transport transmembrane ATP-binding protein ABC transporter. Highly similar to many proposed ABC transporter proteins including: Mycobacterium tuberculosis Rv1273c SW:YC73_MYCTU (Q11046) (582 aa), Fasta scores: E(): 0, 78.4% identity in 583 aa overlap and Bacillus subtilis hypothetical ABC transporter ATP-binding protein SW:YFIB_BACSU (P54718) (573 aa), Fasta scores: E(): 0, 34.4% identity in 569 aa overlap. Also similar to the adjoining CDS ML1113c. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.;UniProt_AC=Q9CC88;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1299723	1301396	.	-	0	Locus=ML1121c;Name=oppA;Function=;Product=PROBABLE PERIPLASMIC OLIGOPEPTIDE-BINDING LIPOPROTEIN OPPA;Comments=ML1121c, len: 557 aa. Probable oppA, oligopeptide-binding lipoprotein component of peptide transport system. Similar to several including: Mycobacterium tuberculosis extracellular solute-binding Rv1280c SW:YC80_MYCTU (Q11041) (591 aa), Fasta scores: E(): 0, 80.3% identity in 548 aa overlap and Escherichia coli putative binding protein YddS precursor SW:YDDS_ECOLI (P76128) (516 aa), Fasta scores: E(): 2.3e-10, 22.5% identity in 480 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. BELONGS TO THE BACTERIAL EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 5.;UniProt_AC=Q9CC82;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1316574	1318226	.	+	0	Locus=ML1127;Name=argS;Function=;Product=PROBABLE ARGINYL-TRNA SYNTHETASE ARGS (ARGRS) (Arginine--tRNA ligase);Comments=ML1127, len: 550 aa. Probable argS, arginyl-tRNA synthase (EC  6.1.1.19). Identical to the previously sequenced Mycobacterium leprae arginyl-tRNA synthetase (arginine--tRNA ligase) SW:SYR_MYCLE (P45840) (550 aa), Fasta scores: E(): 0, 99.6% identity in 550 aa overlap. Also highly similar to many other  arginyl-tRNA synthetases including: Mycobacterium tuberculosis Rv1292 SW:SYR_MYCTU (Q10609) (550 aa), Fasta scores: E(): 0, 84.9% identity in 550 aa overlap and Brevibacterium lactofermentum SW:SYR_BRELA (P41253) (550 aa), Fasta scores: E(): 0, 63.8% identity in 550 aa overlap. Contains Pfam match to entry PF00750 tRNA-synt_1d, tRNA synthetases class I (R). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature.;UniProt_AC=P45840;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2762496	2762933	.	-	0	Locus=ML2332c;Name=ML2332c;Function=;Product=conserved hypothetical protein;Comments=ML2332c, len: 145 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 15.7 kDa protein Rv3718c TR:O69685 (EMBL:AL022121) (147 aa) fasta scores: E(): 0, 81.9% identity in 144 aa and Streptomyces coelicolor conserved hypothetical protein TR:Q9ZBJ2 (EMBL:AL035161) (147 aa) fasta scores: E(): 1.4e-22, 47.6% identity in 147 aa.;UniProt_AC=O69517;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1331274	1331519	.	+	0	Locus=ML1140;Name=atpE;Function=;Product=PROBABLE ATP SYNTHASE C CHAIN ATPE (LIPID-BINDING PROTEIN) (DICYCLOHEXYLCARBODIIMIDE-BINDING PROTEIN);Comments=ML1140, len: 81 aa. Probable atpE, ATP synthase C chain (EC 3.6.3.14). Identical to the previously sequenced Mycobacterium leprae ATP synthase C chain protein SW:ATPL_MYCLE (P45828) (81 aa), Fasta scores: E(): 1.1e-25, 100.0% identity in 81 aa overlap. Also highly similar to many other Prokaryotic and Eukaryotic proposed ATPase C chain family proteins e.g. Mycobacterium tuberculosis Rv1305 SW:ATPL_MYCTU (Q10598) (81 aa), Fasta scores: E(): 6.4e-24, 92.6% identity in 81 aa overlap and Euglena gracilis SW:ATPH_EUGGR (P10603) (81 aa), Fasta scores: E(): 4.8e-06, 36.7% identity in 79 aa overlap. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00137 ATP-synt_C, ATP synthase subunit C. Contains PS00605 ATP synthase c subunit signature.;UniProt_AC=P45828;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1336078	1337535	.	+	0	Locus=ML1145;Name=atpD;Function=;Product=PROBABLE ATP SYNTHASE BETA CHAIN ATPD;Comments=ML1145, len: 485 aa. Probable atpD, ATP synthase [beta] chain (EC 3.6.3.14). Identical to the previously sequenced Mycobacterium leprae ATP synthase beta chain (EC 3.6.1.34) SW:ATPB_MYCLE (P45823) (485 aa), Fasta scores: E(): 0, 100.0% identity in 485 aa overlap. Also highly similar to many other proposed ATPase beta chain family proteins e.g. Mycobacterium tuberculosis Rv1310 SW:ATPB_MYCTU (Q10593) (486 aa), Fasta scores: E(): 0, 92.6% identity in 484 aa overlap and Streptomyces lividan SW:ATPB_STRLI (P50004) (477 aa), Fasta scores: E(): 0, 70.3% identity in 478 aa overlap. Contains Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family. Contains Pfam match to entry PF00306 ATP-synt_ab_C, ATP synthase ab C terminal. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00152 ATP synthase alpha and beta subunits signature.;UniProt_AC=P45823;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3128842	3131709	.	-	0	Locus=ML2620c;Name=mmpL3;Function=;Product=POSSIBLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL3;Comments=ML2620c, len: 955 aa. Possible mmpl3, conserved transmembrane transport protein. Similar to many Mycobacterium tuberculosis mmp-family membrane proteins e.g. Mmpl3 OR Rv0206c SW:MML3_MYCTU (O53657) fasta scores: E(): 0, 75.7% identity in 966 aa, and to Streptomyces coelicolor putative membrane transport protein SCF51A.01C TR:Q9RL63 (EMBL:AL121596) fasta scores: E(): 0, 28.8% identity in 791 aa. Also similar to ML2617 from M. leprae. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=O06081;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1346363	1346860	.	-	0	Locus=ML1151c;Name=ogt;Function=REPAIR OF ALKYLATED GUANINE IN DNA BY STOICHIOMETRICALLY TRANSFERRING THE ALKYL GROUP AT THE O-6 POSITION TO A CYSTEINE RESIDUE IN THE ENZYME. THIS IS A SUICIDE REACTION: THE ENZYME IS IRREVERSIBLY INACTIVATED [CATALYTIC ACTIVITY : DNA (CONTAINING 6-O-METHYLGUANINE) + [PROTEIN]-L-CYSTEINE = DNA (WITHOUT 6-O-METHYLGUANINE) + PROTEIN  S-METHYL-L-CYSTEINE.];Product=PROBABLE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase);Comments=ML1151c, len: 165 aa. Probable methylated-DNA-protein-cysteine methyltransferase (EC 2.1.1.63). Identical to the previously sequenced Mycobacterium leprae putative methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) SW:OGT_MYCLE (P52982) (165 aa), Fasta scores: E(): 0, 100.0% identity in 165 aa overlap. Also highly similar to many others e.g. Mycobacterium tuberculosis Rv1316c SW:OGT_MYCTU (Q10627) (165 aa), Fasta scores: E(): 0, 78.2% identity in 165 aa overlap and Bacillus subtilis SW:OGT_BACSU (P11742) (165 aa), Fasta scores: E(): 1e-20, 44.7% identity in 159 aa overlap. Contains Pfam match to entry PF01035 Methyltransf_1, 6-O-methylguanine DNA methyltransferase. Contains PS00374 Methylated-DNA--protein-cysteine methyltransferase active site.;UniProt_AC=P52982;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1352356	1352823	.	-	0	Locus=ML1157c;Name=ML1157c;Function=;Product=conserved hypothetical protein;Comments=ML1157c, len: 155 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae TR:Q49717 (EMBL:U00014) (155 aa), Fasta scores: E(): 0, 99.4% identity in 155 aa overlap. Similar to Q8VK36 Conserved hypothetical protein from M. tuberculosis (152 aa), fasta scores: E(): 2.8e-47, 74.675% identity in 154 aa overlap and Streptomyces coelicolor conserved hypothetical protein TR:CAB70628 (EMBL:AL137242) (146 aa), Fasta scores: E(): 1.5e-19, 42.1% identity in 140 aa overlap. Contains Pfam match to entry PF01626 4HPPD_C, 4-hydroxyphenylpyruvate dioxygenase C terminal domain.;UniProt_AC=Q49717;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1365554	1366642	.	+	0	Locus=ML1167;Name=ML1167;Function=;Product=PROBABLE HYDROLASE;Comments=ML1167, len: 362 aa. Probable Hydrolase. Previously sequenced Mycobacterium leprae hypothetical protein SW:YD33_MYCLE (P53425) (362 aa), Fasta scores: E(): 0, 100.0% identity in 362 aa overlap. Similar to Mycobacterium tuberculosis Rv1333 TR:YD33_MYCTU Q10644 Probable Hydrolase (344 aa), fasta scores: E(): 3.1e-97, (76.705% identity in 352 aa overlap); and Streptomyces coelicolor TR:CAB90977 (EMBL:AL355832) Hypothetical protein (348 aa), Fasta scores: E(): 0, (48.2% identity in 365 aa overlap); and Flavobacterium sp. TR:Q57326 (EMBL:D26094) endo-type 6-aminohexanoate oligomer hydrolase (355 aa), Fasta scores: E(): 1.4e-11, 31.6% identity in 351 aa overlap.;UniProt_AC=P53425;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1369208	1370026	.	+	0	Locus=ML1172;Name=murI;Function=;Product=PROBABLE GLUTAMATE RACEMASE MURI;Comments=ML1172, len: 272 aa. Probable glutamate racemase (EC 5.1.1.3). Identical to the previously sequenced Mycobacterium leprae probable glutamate racemase (EC 5.1.1.3) SW:MURI_MYCLE (P46705) (272 aa), Fasta scores: E(): 0, 100.0% identity in 272 aa overlap. Also highly similar to many others involved in peptidoglycan biosynthesis including glutamate racemases from Mycobacterium tuberculosis Rv1338 SW:MURI_MYCTU (Q10626) (271 aa), Fasta scores: E(): 0, 88.9% identity in 271 aa overlap and Bacillus subtilis SW:MURI_BACSU (P94556) (272 aa), Fasta scores: E(): 0, 42.2% identity in 268 aa overlap. Contains Pfam match to entry PF01177 Asp_Glu_race, Aspartate / glutamate racemase. Contains PS00924 Aspartate and glutamate racemases signature 2. Contains PS00923 Aspartate and glutamate racemases signature 1.;UniProt_AC=P46705;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3176736	3177233	.	+	0	Locus=ML2654;Name=ML2654;Function=;Product=conserved hypothetical protein;Comments=ML2654, len: 165 aa. Conserved hypothetical protein. Similar to many proteins of undefined function e.g. Streptomyces coelicolor hypothetical 18.3 kda protein TR:Q9RJE5 (EMBL:AL133171) fasta scores: E(): 0, 60.1% in 163 aa. Contains Pfam match to entry PF01143 UPF0025, Uncharacterized protein family UPF0025.;UniProt_AC=Q9CCZ0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1396625	1405855	.	+	0	Locus=ML1191;Name=fas;Function=;Product=PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE);Comments=ML1191, len: 3076 aa. Probable fas, fatty acid synthase (EC 2.3.1.-). Identical to the previously sequenced Mycobacterium leprae putative type I fatty acid synthase TR:Q9X7E2 (EMBL:AL049478) (3076 aa), Fasta scores: E(): 0, 100.0% identity in 3076 aa overlap. Also highly similar to many other fatty acid synthases including: Mycobacterium tuberculosis Rv2524c TR:P95029 (EMBL:Z83863) (3069 aa), Fasta scores: E(): 0, 85.8% identity in 3081 aa overlap and Corynebacterium ammoniagenes fatty-acid synthase (EC 2.3.1.85) TR:Q59497 (EMBL:X87822) (3063 aa), Fasta scores: E(): 0, 44.3% identity in 3106 aa overlap. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF01575 MaoC_dehydratas, MaoC like domain. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q9X7E2;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1417032	1417637	.	+	0	Locus=ML1199;Name=lspA;Function=THIS PROTEIN SPECIFICALLY CATALYZES THE REMOVAL OF SIGNAL PEPTIDES FROM PROLIPOPROTEINS [CATALYTIC ACTIVITY : CLEAVAGE OF N-TERMINAL LEADER SEQUENCES FROM MEMBRANE PROLIPOPROTEINS. HYDROLYSES XAA-XBB-XBB-|-CYS, IN WHICH XAA IS HYDROPHOBIC (PREFERABLY LEU), XBB IS OFTEN SER OR ALA, XCC IS OFTEN GLY OR ALA, AND THE CYS IS ALKYLATED ON SULFUR WITH A DIACYLGLYCERYL GROUP].;Product=PROBABLE LIPOPROTEIN SIGNAL PEPTIDASE LSPA;Comments=ML1199, len: 201 aa. Probable lspA, lipoprotein signal peptidase (EC 3.4.23.36). Identical to the previously sequenced Mycobacterium leprae lipoprotein signal peptidase TR:Q9X7E7 (EMBL:AL049478) (201 aa), Fasta scores: E(): 0, 100.0% identity in 201 aa overlap. Also highly similar to lipoprotein signal peptidases from: Mycobacterium tuberculosis Rv1539 SW:LSPA_MYCTU (Q10764) (202 aa), Fasta scores: E(): 0, 80.6% identity in 201 aa overlap and Bacillus subtilis SW:LSPA_BACSU (Q45479) (154 aa), Fasta scores: E(): 1.2e-12, 36.8% identity in 163 aa overlap. Contains Pfam match to entry PF01252 Peptidase_A8, Signal peptidase (SPase) II. Contains PS00855 Signal peptidases II signature.;UniProt_AC=Q9X7E7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1434682	1436883	.	-	0	Locus=ML1213c;Name=ML1213c;Function=;Product=CONSERVED HYPOTHETICAL MEMBRANE PROTEIN;Comments=ML1213c, len: 733 aa. Conserved hypothetical membrane protein.  Previously sequenced Mycobacterium leprae putative membrane protein (fragment) TR:Q9X7F3 (EMBL:AL049478) (274 aa), Fasta scores: E(): 0, 100.0% identity in 274 aa overlap. Also similar to a number of Prokaryotic and Eukaryotic proteins of undefined function including: Mycobacterium tuberculosis Rv1565c TR:O06625 (EMBL:Z95586) (729 aa), Fasta scores: E(): 0, 76.5% identity in 729 aa overlap and Caenorhabditis elegans TR:O62230 (EMBL:Z81528) (698 aa), Fasta scores: E(): 5.2e-09, 24.8% identity in 646 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CC68;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1439917	1441074	.	+	0	Locus=ML1217;Name=bioF;Function=;Product=PROBABLE 8-AMINO-7-OXONONANOATE SYNTHASE BIOF (AONS) (8-AMINO-7-KETOPELARGONATE SYNTHASE) (7-KETO-8-AMINO-PELARGONIC ACID SYNTHETASE) (7-KAP SYNTHETASE) (L-ALANINE--PIMELYL CoA LIGASE);Comments=ML1217, len: 385 aa. Probable bioF1, 8-amino-7-oxononanoate synthase (EC 2.3.1.47)Identical to the previously sequenced Mycobacterium leprae 8-amino-7-oxononanoate synthase (EC 2.3.1.47) SW:BIOF_MYCLE (P45487) (385 aa), Fasta scores: E(): 0, 100.0% identity in 385 aa overlap. Also highly similar to many othes e.g. Escherichia coli SW:BIOF_ECOLI (P12998) (384 aa), Fasta scores: E(): 0, 36.9% identity in 379 aa overlap, involved in biotin biosynthesis, and Mycobacterium tuberculosis Rv1569 SW:BIOF_MYCTU (O06621) (386 aa), Fasta scores: E(): 0, 80.1% identity in 381 aa overlap. Contains Pfam match to entry PF00222 aminotran_2, Aminotransferases class-II. Contains PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. BELONGS TO CLASS-II OF PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES.;UniProt_AC=P45487;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1446716	1447774	.	+	0	Locus=ML1225;Name=nadA;Function=;Product=Probable quinolinate synthetase A NadA;Comments=ML1225, len: 352 aa. Probable nadA, quinolinate synthetase. Identical to the previously sequenced Mycobacterium leprae probable quinolinate synthetase A TR:Q49622 (EMBL:U00010) (368 aa), Fasta scores: E(): 0, 100.0% identity in 352 aa overlap. Also similar to quinolinate synthetases from Escherichia coli SW:NADA_ECOLI (P11458) (347 aa), Fasta scores: E(): 2.6e-27, 33.3% identity in 330 aa overlap and Mycobacterium tuberculosis Rv1594 TR:O06596 (EMBL:Z95586) (349 aa), Fasta scores: E(): 0, 84.4% identity in 352 aa overlap. Belongs to the quinolinate synthetase A family. Subfamily 2.;UniProt_AC=Q49622;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2884103	2884711	.	-	0	Locus=ML2413c;Name=ML2413c;Function=;Product=Possible phosphoglycerate mutase;Comments=ML2413c, len: 202 aa. Possible phosphoglycerate mutase (EC 5.4.2.1). Similar to Mycobacterium tuberculosis conserved hypothetical protein Rv0525 TR:O06391 (EMBL:Z95558) (202 aa) fasta scores: E(): 0, 82.5% identity in 200 aa, and to Escherichia coli probable phosphoglycerate mutase SW:PMG2_ECOLI (P36942) (215 aa) fasta scores: E(): 0.002, 26.1% identity in 184 aa. Contains Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase family.;UniProt_AC=Q49821;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1447771	1449354	.	+	0	Locus=ML1226;Name=nadB;Function=QUINOLINATE BIOSYNTHESIS. CATALYZES THE OXIDATION OF L-ASPARTATE TO IMINOASPARTATE WHICH IS CONDENSED WITH DIHYDROXYACETONE PHOSPHATE TO QUINOLINATE UNDER THE ACTION OF QUINOLINATE SYNTHASE A [CATALYTIC ACTIVITY : L-ASPARTATE + H(2)O + O(2) = OXALOACETATE + NH(3) + H(2)O(2)];Product=Probable L-aspartate oxidase NadB;Comments=ML1226, len: 286 aa. Probable nadB, L-aspartate oxidase (EC 1.4.3.16). Previously sequenced Mycobacterium leprae L-aspartate oxidase SW:NADB_MYCLE (Q49617) (424 aa), Fasta scores: E(): 0, 99.8% identity in 400 aa overlap. Note ML1226 differs in length from that previously sequenced, possibly due to a frameshift in the original sequence. Highly similar to several proteins involved in quinolinate biosynthesis e.g. Mycobacterium tuberculosis Rv1595 SW:NADB_MYCTU (O06595) (527 aa), Fasta scores: E(): 0, 76.7% identity in 529 aa overlap and Escherichia coli SW:NADB_ECOLI (P10902) (540 aa), Fasta scores: E(): 6.2e-31, 38.8% identity in 533 aa overlap. Contains Pfam match to entry PF00890 FAD_binding_2, FAD binding domain.;UniProt_AC=Q49617;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1460739	1462154	.	+	0	Locus=ML1230;Name=papA3;Function=;Product=PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA3;Comments=ML1230, len: 471 aa. Probable papA3, conserved polyketide synthase associated protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49618 (EMBL:U00010) (471 aa), Fasta scores: E(): 0, 99.8% identity in 471 aa overlap. Also highly similar to Mycobacterium tuberculosis proteins encoded downstream of several polyketide synthases e.g. Rv1182 TR:O50438 (EMBL:AL010186) (472 aa), Fasta scores: E(): 0, 75.8% identity in 471 aa overlap.;UniProt_AC=Q49618;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1233352	1234566	.	+	0	Locus=ML1069;Name=glgC;Function=;Product=PROBABLE GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE GLGC (ADP-glucose synthase) (ADP-glucose pyrophosphorylase);Comments=ML1069, len: 404 aa. Probable glgC, glucose-1-phosphate adenylyltransferase (EC 2.7.7.27). Identical to the previously sequenced Mycobacterium leprae GlgC TR:Q49961 (EMBL:U15180) (419 aa), Fasta scores: E(): 0, 100.0% identity in 404 aa overlap. Also highly similar to many glucose-1-phosphate adenylyltransferases involved in glycogen biosynthesis e.g. from Mycobacterium tuberculosis Rv1213 SW:GLGC_MYCTU (O05314) (404 aa), Fasta scores: E(): 0, 92.6% identity in 404 aa overlap and Escherichia coli SW:GLGC_ECOLI (P00584) (430 aa), Fasta scores: E(): 0, 39.6% identity in 407 aa overlap. Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase. Contains PS00809 ADP-glucose pyrophosphorylase signature 2. Contains PS00810 ADP-glucose pyrophosphorylase signature 3. Contains PS00808 ADP-glucose pyrophosphorylase signature 1. BELONGS TO THE BACTERIAL AND PLANTS GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE FAMILY.;UniProt_AC=Q9CCA8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1489173	1490843	.	+	0	Locus=ML1248;Name=ML1248;Function=;Product=PROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER;Comments=ML1248, len: 556 aa. Probable ATP binding protein ABC-transporter. Highly similar to many proposed ABC-transporter ATP-binding proteins including: Escherichia coli SW: YJJK_ECOLI and Mycobacterium tuberculosis Rv2477c TR:O53204 (EMBL:AL021246) (558 aa), Fasta scores: E(): 0, 92.3% identity in 557 aa overlap. Contains 2 Pfam matches to entry PF00005 ABC_tran, ABC transporter. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop). Contains 2 x PS00211 ABC transporters family signature.;UniProt_AC=Q9X7B1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1504776	1505408	.	+	0	Locus=ML1259;Name=hisB;Function=;Product=Probable imidazole glycerol-phosphate dehydratase HisB;Comments=ML1259, len: 210 aa. Probable hisB, imidazole glycerol-phosphate dehydratase (EC 4.2.1.19). Highly similar to many imidazoleglycerol-phosphate dehydratases involved in histidine biosynthesis e.g. from Mycobacterium tuberculosis Rv1601 SW:HIS7_MYCTU (O06590) (210 aa), Fasta scores: E(): 0, 84.8% identity in 210 aa overlap and Streptomyces coelicolor SW:HIS7_STRCO (P16247) (197 aa), Fasta scores: E(): 0, 56.4% identity in 202 aa overlap. Contains 2 Pfam matches to entry PF00475 IGPD, Imidazoleglycerol-phosphate dehydratase. Contains PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. Contains PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. Belongs to the imidazoleglycerol-phosphate dehydratase family.;UniProt_AC=Q9X7B9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1513728	1514525	.	+	0	Locus=ML1270;Name=ML1270;Function=;Product=possible conserved membrane protein;Comments=ML1270, len: 265 aa. Possible conserved membrane protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1610 TR:O06128 (EMBL:Z95554) (235 aa), Fasta scores: E(): 0, 65.8% identity in 231 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00218 IGPS, Indole-3-glycerol phosphate synthases.;UniProt_AC=Q9CC55;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1740908	1741462	.	+	0	Locus=ML1448;Name=sigC;Function=;Product=PROBABLE RNA POLYMERASE SIGMA FACTOR, ECF SUBFAMILY, SIGC;Comments=ML1448, len: 184 aa. Probable sigC, RNA polymerase sigma factor, ECF subfamily. Similar to many ECF-subfamily RNA polymerase sigma factors including: Bacillus subtilis SigX SW:SIGX_BACSU (P35165) (194 aa), Fasta scores: E(): 1.3e-07, 32.0% identity in 128 aa overlap and Mycobacterium tuberculosis Rv2069 SW:RPSC_MYCTU (Q10679) (185 aa), Fasta scores: E(): 0, 81.2% identity in 181 aa overlap. Also similar to ML1956c a possible pseudogene similar to M. tuberculosis sigC. Contains a putative helix-turn-helix motif situated between residues 156..177 (+2.77 SD). Contains a probable helix-turn-helix motif at aa 146-167 (Score 1052, SD +2.77) Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). Contains PS01063 Sigma-70 factors ECF subfamily signature. Belongs to ECF subfamily.;UniProt_AC=Q9CC01;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1531870	1532487	.	+	0	Locus=ML1286;Name=ML1286;Function=;Product=Probable two-component system transcriptional regulator;Comments=ML1286, len: 205 aa. Probable two-component system transcriptional regulator. Similar to many proposed two-component response regulators including: Streptomyces coelicolor TR:Q9S2J0 (EMBL:AL109732) (218 aa), Fasta scores: E(): 0, 65.3% identity in 202 aa overlap and Azotobacter vinelandii TR:Q44531 (EMBL:X83602) (192 aa), Fasta scores: E(): 4.5e-11, 30.1% identity in 186 aa overlap. Also highly similar to Mycobacterium tuberculosis probable two-component response system transcriptional regulator Rv1626 TR:O06143 (EMBL:Z95554) (205 aa), Fasta scores: E(): 0, 90.7% identity in 205 aa overlap. Contains Pfam match to entry PF00072 response_reg, Response regulator receiver domain.;UniProt_AC=Q9CC47;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1189188	1190912	.	-	0	Locus=ML1022c;Name=sigA;Function=;Product=RNA polymerase sigma factor SigA;Comments=ML1022c, len: 574 aa. Probable sigA (also known as rpoT), RNA polymerase sigma factor. Identical to the previously sequenced Mycobacterium leprae RNA polymerase sigma factor, rpoT TR:Q59532 (EMBL:U15181) (574 aa), Fasta scores: E(): 0, 99.8% identity in 574 aa overlap. Also highly similar to many other proposed sigma factors e.g. Mycobacterium tuberculosis SigA (RpoD), RNA polymerase sigma factor Rv2703 SW:RPSA_MYCTU (Q60162) (528 aa), Fasta scores: E(): 0, 80.5% identity in 533 aa overlap. The C-terminus is highly similar to ML1014 from M. leprae. Contains a probable helix-turn-helix motif at aa 533-554 (Score 1603, SD +4.65) Contains Pfam match to entry PF00140 sigma70, Sigma-70 factor. Contains PS00716 Sigma-70 factors family signature 2. Contains PS00715 Sigma-70 factors family signature 1. Belongs to the sigma-70 factor family. Previously known as rpoT.;UniProt_AC=Q59532;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1260031	1263813	.	-	0	Locus=ML1095c;Name=sucA;Function=THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-CoA & CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS:2-OXOGLUTARATE DEHYDROGENASE (E1), DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) [CATALYTIC ACTIVITY: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2];Product=PROBABLE 2-OXOGLUTARATE DEHYDROGENASE SUCA (Alpha-ketoglutarate dehydrogenase);Comments=ML1095c, len: 1260 aa. Probable sucA, 2-oxoglutarate dehydrogenase (EC 1.2.4.2). This CDS appears to constitute the E1  components of the 2-oxoglutarate dehydrogenase complex.  The predicted product of this CDS is similar to several 2-oxoglutarate dehydrogenase e.g. Mycobacterium tuberculosis Rv1248c TR:O50463 (EMBL:AL021006) (1214 aa), Fasta scores: E(): 0, 89.0% identity in 1224 aa overlap and Corynebacterium glutamicum TR:P96746 (EMBL:D84102) (1257 aa), Fasta scores: E(): 0, 58.9% identity in 1253 aa overlap. Contains Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase (catalytic domain). Contains Pfam match to entry PF00676 E1_dehydrog, Dehydrogenase E1 component. Previously known as odhA.;UniProt_AC=Q9CC97;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1405884	1406276	.	+	0	Locus=ML1192;Name=acpS;Function=BIOSYNTHESIS OF FATTY ACIDS AND LIPIDS. TRANSFERS THE 4'-PHOSPHOPANTETHEINE MOIETY FROM COENZYME A TO A SER OF ACYL-CARRIER PROTEIN. CATALYZES THE FORMATION OF HOLO-ACP, WHICH MEDIATES THE TRANSFER OF ACYL FATTY-ACID INTERMEDIATES DURING THE BIOSYNTHESIS OF FATTY ACIDS AND LIPIDS [CATALYTIC ACTIVITY: CoA + APO-[ACYL-CARRIER PROTEIN] = ADENOSINE 3',5'-BISPHOSPHATE + HOLO-[ACYL-CARRIER PROTEIN] ].;Product=HOLO-[ACYL-CARRIER PROTEIN] SYNTHASE ACPS (HOLO-ACP SYNTHASE) (CoA:APO-[ACP]PANTETHEINEPHOSPHOTRANSFERASE) (CoA:APO-[ACYL-CARRIER PROTEIN]PANTETHEINEPHOSPHOTRANSFERASE);Comments=ML1192, len: 130 aa. Probable acpS, holo-[acyl-carrier protein] synthase (EC 2.7.8.7). Identical to the previously sequenced Mycobacterium leprae holo-[acyl-carrier protein] synthase (ACP) SW:ACPS_MYCLE (Q9X7E3) (130 aa), Fasta scores: E(): 0, 99.2% identity in 130 aa overlap. Also highly similar to ACPs from Mycobacterium tuberculosis Rv2523c SW:ACPS_MYCTU (O53228) (130 aa), Fasta scores: E(): 0, 86.7% identity in 128 aa overlap and Escherichia coli SW:ACPS_ECOLI (P24224) (125 aa), Fasta scores: E(): 0.00025, 35.1% identity in 131 aa overlap. Contains Pfam match to entry PF01648 ACPS, 4'-phosphopantetheinyl transferase superfamily.;UniProt_AC=Q9X7E3;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1279265	1279954	.	+	0	Locus=ML1105;Name=udgB;Function=;Product=conserved hypothetical protein;Comments=ML1105, len: 229 aa. Conserved hypothetical protein. Similar to many proteins of undefined function including: Mycobacterium tuberculosis Rv1259 SW:YC59_MYCTU (Q11059) (299 aa), Fasta scores: E(): 0, 85.5% identity in 228 aa overlap and Streptomyces coelicolor TR:Q9S2L3 (EMBL:AL109732) (237 aa), Fasta scores: E(): 0, 54.5% identity in 231 aa overlap.;UniProt_AC=Q9CC91;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1199240	1200529	.	-	0	Locus=ML1036c;Name=arsA;Function=;Product=PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSA;Comments=ML1036c, len: 429 aa. Probable arsA, arsenic-transport integral membrane protein. Identical to the previously sequenced Mycobacterium leprae probable membrane transport protein SW:AG45_MYCLE (P46838) (429 aa), Fasta scores: E(): 0, 99.8% identity in 429 aa overlap. Also highly similar to Mycobacterium tuberculosis arsenic-transport integral membrane proteins Rv2684 YQ84_MYCTU (O07186) (429 aa), Fasta scores: E(): 0, 74.3% identity in 428 aa overlap and O07187|YQ85_MYCTU|Rv2685 (428 aa), fasta scores: E(): 3.3e-128, (74.239% identity in 427 aa overlap). Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=P46838;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2201528	2201920	.	-	0	Locus=ML1818c;Name=trxB;Function=;Product=PROBABLE THIOREDOXIN TRXB;Comments=ML1818c, len: 130 aa. Probable trxB, thioredoxin. Similar to M. tuberculosis thioredoxin trxB1 Rv1471 TR:O53162 (EMBL:AL021184) (123 aa), Fasta scores: E(): 2.4e-25, 65.4% identity in 107 aa overlap, and M. tuberculosis thioredoxin trxA Rv1470 TR:O53161 (EMBL:AL021184) (124 aa), Fasta scores: E(): 1.6e-17, 47.0% identity in 117 aa overlap. Also similar to Escherichia coli thioredoxin 2 SW:THI2_ECOLI (P33636) (139 aa), Fasta scores: E(): 1.7e-07, 37.1% identity in 89 aa overlap. Also similar to ML2703 from M. leprae. Contains Pfam match to entry PF00085 thiored, Thioredoxin.;UniProt_AC=Q9CBL1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1333461	1335137	.	+	0	Locus=ML1143;Name=atpA;Function=;Product=PROBABLE ATP SYNTHASE ALPHA CHAIN ATPA;Comments=ML1143, len: 558 aa. Probable atpA, ATP synthase [alpha] chain (EC 3.6.3.14). Identical to the previously sequenced Mycobacterium leprae ATP synthase alpha chain (EC 3.6.1.34) SW:ATPA_MYCLE (P45825) (558 aa), Fasta scores: E(): 0, 100.0% identity in 558 aa overlap. Also highly similar to many other proposed ATPase alpha chain family proteins e.g. Mycobacterium tuberculosis Rv1308 TR:ATPA_MYCTU and Streptomyces lividans SW:ATPA_STRLI (P50001) (528 aa), Fasta scores: E(): 0, 69.0% identity in 516 aa overlap. Contains Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family. Contains Pfam match to entry PF00422 ATP-synt_A-c, ATP synthase Alpha chain, C terminal. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00152 ATP synthase alpha and beta subunits signature.;UniProt_AC=P45825;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1032059	1033114	.	-	0	Locus=ML0868c;Name=cobT;Function=Involved in Cobalamin biosynthesis. Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). [Catalytic activity : Beta-nicotinate D-ribonucleotide + dimethylbenzimidazole = nicotinate + N1-(5-phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole.;Product=Probablenicotinate-nucleotide-dimethylbenzimidazol phosphoribosyltransferase CobT;Comments=ML0868c, len: 351 aa. Probable cobT, nicotinate-nucleotide-dimethylbenzimidazol phosphoribosyltransferase (EC 2.4.2.21). Similar to Mycobacterium tuberculosis putative nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase cobT or Rv2207 or MTCY190.18 SW:COBT_MYCTU (Q10396) (361 aa) fasta scores: E(): 0, 81.4% identity in 355 aa. Similar to many e.g. Salmonella typhimurium nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase cobT SW:COBT_SALTY (Q05603) (356 aa) fasta scores: E(): 5.9e-32, 34.1% identity in 340 aa. Previously sequenced as O32953 (EMBL:Z98741). Belongs to the cobT family. ;UniProt_AC=O32953;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1164320	1165210	.	+	0	Locus=ML0996;Name=dapF;Function=;Product=PROBABLE DIAMINOPIMELATE EPIMERASE DAPF (DAP EPIMERASE);Comments=ML0996, len: 296 aa. Probable dapF, diaminopimelate epimerase (EC 5.1.1.7). Identical to the previously sequenced Mycobacterium leprae  diaminopimelate epimerase (DAP epimerase) involved in the biosynthesis of lysine from aspartate semialdehyde SW:DAPF_MYCLE (P46814) (296 aa), Fasta scores: E(): 0, 100.0% identity in 296 aa overlap. Also highly similar to DAP epimerases from Mycobacterium tuberculosis Rv2726c SW:DAPF_MYCTU (O33231) (289 aa), Fasta scores: E(): 0, 76.0% identity in 292 aa overlap and Escherichia coli SW:DAPF_ECOLI (P08885) (274 aa), Fasta scores: E(): 4.2e-13, 32.3% identity in 294 aa overlap. Contains Pfam match to entry PF01678 DAP_epimerase, Diaminopimelate epimerase. Contains PS01326 Diaminopimelate epimerase signature. Belongs to the diaminopimelate epimerase family.;UniProt_AC=P46814;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1201218	1203149	.	+	0	Locus=ML1038;Name=dxs;Function=INVOLVED IN THE DEOXYXYLULOSE-5-PHOSPHATE PATHWAY (DXP) OF ISOPRENOIDBIOSYNTHESIS (AT THE FIRST STEP), AND IN THE BIOSYNTHETIC PATHWAY TO THIAMINE AND PYRIDOXOL (AT THE FIRST STEP). CATALYZES THE ACYLOIN CONDENSATION REACTION BETWEEN ATOMS 2 AND 3 OF PYRUVATE AND GLYCERALDEHYDE 3-PHOSPHATE TO YIELD 1-DEOXY-D-XYLULOSE-5-PHOSPHATE (DXP).;Product=PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE DXS1 (1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE) (DXP SYNTHASE) (DXPS);Comments=ML1038, len: 643 aa. Probable dxs1, 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.-.-). Identical to the previously sequenced Mycobacterium leprae probable 1-deoxyxylulose-5-phosphate synthase (DXP synthase) SW:DXS_MYCL (Q50000) (643 aa), Fasta scores: E(): 0, 100.0% identity in 643 aa overlap. Also highly similar to many members of the transketolase family including DXP synthases from Mycobacterium tuberculosis Rv2682c SW:DXS_MYCTU (O07184) (638 aa), Fasta scores: E(): 0, 86.4% identity in 632 aa overlap and Escherichia coli SW:DXS_ECOLI (P77488) (619 aa), Fasta scores: E(): 0, 39.2% identity in 625 aa overlap. Contains PS00801 Transketolase signature 1. Contains PS00802 Transketolase signature 2.;UniProt_AC=Q50000;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1024956	1026746	.	+	0	Locus=ML0862;Name=ephD;Function=;Product=Possible short-chain dehydrogenase EphD;Comments=ML0862, len: 596 aa. Possible ephD, short-chain dehydrogenase. Similar to Mycobacterium tuberculosis probable oxidoreductase ephD or Rv2214c or MTCY190.25C SW:EPHD_MYCTU (Q10402) (592 aa) fasta scores: E(): 0, 80.4% identity in 596 aa. Similar to many putative oxidorecuctases e.g. Streptomyces coelicolor putative oxidoreductase SCD78.21C TR:Q9ZBX8 (EMBL:AL034355) (585 aa) fasta scores: E(): 0, 42.4% id in 582 aa. C-terminal half is similar to Pseudomonas paucimobilis C alpha-dehydrogenase ligD SW:LIGD_PSEPA (Q01198) (305 aa) fasta scores: E(): 1.1e-15, 26.8% id in 269 aa. Previously sequenced as TR:O32958 (EMBL:Z98741). Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature. BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY.;UniProt_AC=O32958;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1053286	1055088	.	-	0	Locus=ML0887c;Name=fadD15;Function=;Product=Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE);Comments=ML0887c, len: 600 aa. Probable fadD15, long-chain-fatty-acid-CoA ligase (EC 6.2.1.3). Similar to Mycobacterium tuberculosis putative long-chain-fatty-acid-CoA ligase, fadD15, TR:O53521 (EMBL:AL021957) (600 aa), Fasta scores: E(): 0, 80.3% identity in 600 aa overlap. The C-terminus of the predicted product of this CDS is identical to the previously sequenced Mycobacterium leprae putative long-chain- fatty-acid-CoA ligase TR:O69578 (EMBL:AL022602) (351 aa), Fasta scores: E(): 0, 100.0% identity in 351 aa overlap. Also similar to Haemophilus influenzae putative long-chain-fatty-acid-CoA ligase (EC 6.2.1.3) SW:LCFH_HAEIN (SW:P44446) (607 aa), Fasta scores: E(): 0, 30.3% identity in 587 aa overlap. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature.;UniProt_AC=Q9CCE6;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1628893	1629699	.	+	0	Locus=ML1368;Name=scpA;Function=;Product=conserved hypothetical protein;Comments=ML1368, len: 268 aa. Conserved hypothetical protein. Similar to many proteins of undefined function e.g. Bacillus subtilis SW:YPUG_BACSU (P35154) (251 aa), Fasta scores: E(): 2e-12, 26.0% identity in 242 aa overlap and Mycobacterium tuberculosis Rv1709 TR:O33208 (EMBL:Z98268) (278 aa), Fasta scores: E(): 0, 78.9% identity in 251 aa overlap.;UniProt_AC=Q49888;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1013842	1016163	.	+	0	Locus=ML0854;Name=gpsI;Function=INVOLVED IN mRNA DEGRADATION. HYDROLYSES SINGLE-STRANDED POLYRIBONUCLEOTIDES PROCESSIVELY IN THE 3' TO 5' DIRECTION. INVOLVED IN THE RNA DEGRADOSOME, A MULTI-ENZYME COMPLEX IMPORTANT IN RNA PROCESSING AND MESSENGER RNA DEGRADATION [CATALYTIC ACTIVITY: RNA(N+1) + PHOSPHATE = RNA(N) + A NUCLEOSIDE DIPHOSPHATE].;Product=BIFUNCTIONAL PROTEIN POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE GPSI: GUANOSINE PENTAPHOSPHATE SYNTHETASE + POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE PHOSPHORYLASE) (PNPASE);Comments=ML0854, len: 773 aa. Probable gpsI, polyribonucleotide nucleotidyltransferase (EC 2.7.7.8; 2.7.6.-). Similar to Mycobacterium tuberculosis guanosine pentaphosphate synthetase / polyribonucleotide nucleotidyltransferase gpsI or Rv2783c or MTV002.48C TR:O33325 (EMBL:AL008967) (752 aa) fasta scores: E(): 0, 90.0% identity in 757 aa, to Streptomyces antibioticus guanosine pentaphosphate synthetase gpsI TR:Q53597 (EMBL:U19858) (740 aa) fasta scores: E(): 0, 67.2% identity in 751 aa and to Bacillus subtilis polyribonucleotide nucleotidyltransferase pnpA or comR SW:PNPA_BACSU (P50849) (704 aa) fasta scores: E(): 0, 45.0% identity in 723 aa. Previously sequenced as TR:O32966 (EMBL:Z98741). Contains Pfam match to entry PF00013 KH-domain, KH domain. Contains 2 Pfam matches to entry PF01138 RNase_PH, 3' exoribonuclease family. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain.;UniProt_AC=Q9CCF8;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1502300	1503649	.	+	0	Locus=ML1257;Name=hisD;Function=Involved in histidine biosynthesis pathway (last step). THIS PROTEIN IS CONSIDERED AS A BIFUNCTIONAL ENZYME, POSSESSING TWO ACTIVE SITES, ONE AN ALCOHOL DEHYDROGENASE AND THE OTHER AN ALDEHYDE DEHYDROGENASE [CATALYTIC ACTIVITY : L-HISTIDINOL + 2 NAD(+) + H(2)O = L-HISTIDINE + 2 NADH].;Product=Probable histidinol dehydrogenase HisD (HDH);Comments=ML1257, len: 449 aa. Probable hisD, histidinol dehydrogenase (EC 1.1.1.23).  Highly similar to many histidinol dehydrogenases constituting the first stage in the histidine biosynthetic pathway e.g. Mycobacterium tuberculosis Rv1599 SW:HISX_MYCTU (Z95586) (438 aa), Fasta scores: E(): 0, 84.8% identity in 442 aa overlap and Mycobacterium smegmatis SW:HISX_MYCSM (P28736) (445 aa), Fasta scores: E(): 0, 77.5% identity in 449 aa overlap. Contains Pfam match to entry PF00815 Histidinol_dh, Histidinol dehydrogenase. Contains PS00611 Histidinol dehydrogenase signature. Belongs to the histidinol dehydrogenase family.;UniProt_AC=Q9CC57;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1325822	1326907	.	+	0	Locus=ML1134;Name=prfA;Function=;Product=PROBABLE PEPTIDE CHAIN RELEASE FACTOR 1 PRFA (RF-1);Comments=ML1134, len: 361 aa. Probable prfA, peptide chain release factor 1. Identical to the previously sequenced Mycobacterium leprae peptide chain release factor 1 (RF-1), directing the termination of translation, SW:RF1_MYCLE (P45833) (357 aa), Fasta scores: E(): 0, 99.7% identity in 357 aa overlap. Also highly similar to many other Prokaryotic and Eukaryotic chain release factors e.g. from Mycobacterium tuberculosis Rv1299 SW:RF1_MYCTU (Q10605) (357 aa), Fasta scores: E(): 0, 89.4% identity in 360 aa overlap and Kluyveromyces lactis (Yeast) SW:RF1M_KLULA (P41767) (396 aa), Fasta scores: E(): 0, 39.9% identity in 368 aa overlap. Contains Pfam match to entry PF00472 RF-1, Peptidyl-tRNA hydrolase domain. Also similar to M. leprae ML0667. Contains PS00745 Prokaryotic-type class I peptide chain release factors signature.;UniProt_AC=P45833;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1410788	1413967	.	+	0	Locus=ML1195;Name=ileS;Function=;Product=isoleucyl-tRNA synthetase IleS;Comments=ML1195, len: 1059 aa. Probable ileS, isoleucyl-tRNA synthase (EC 6.1.1.5). Identical to the previously sequenced Mycobacterium leprae isoleucyl-tRNA synthetase SW:SYI_MYCLE (Q9X7E5) (1059 aa), Fasta scores: E(): 0, 100.0% identity in 1059 aa overlap. Also highly similar to many Prokaryotic and Eukaryotic tRNA synthases e.g. Mycobacterium tuberculosis Rv1536 SW:SYI_MYCTU (Q10765) (1041 aa), Fasta scores: E(): 0, 84.4% identity in 1059 aa overlap and Schizosaccharomyces pombe SW:SYIC_SCHPO (O13651) (1064 aa), Fasta scores: E(): 0, 39.5% identity in 1041 aa overlap. Also similar to ML1472 (valyl-tRNA synthase) from M. leprae. Contains Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature.;UniProt_AC=Q9X7E5;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1428254	1429537	.	+	0	Locus=ML1209;Name=ilvA;Function=INVOLVED IN ISOLEUCINE BIOSYNTHESIS (FIRST STEP). CATALYZES THE FORMATION OF ALPHA-KETOBUTYRATE FROM THREONINE IN A TWO STEP REACTION. THE FIRST STEP IS A DEHYDRATION OF THREONINE, FOLLOWED BY REHYDRATION AND LIBERATION OF AMMONIA [CATALYTIC ACTIVITY : L-THREONINE + H(2)O = 2-OXOBUTANOATE + NH(3) + H(2)O].;Product=Probable threonine dehydratase IlvA;Comments=ML1209, len: 427 aa. Probable ilvA, threonine dehydratase (EC 4.2.1.16). Identical to the previously sequenced Mycobacterium leprae probable threonine deaminase TR:Q9X7F1 (EMBL:AL04947) (427 aa), Fasta scores: E(): 0, 100.0% identity in 427 aa overlap. Highly similar to many other threonine dehydratase including: Mycobacterium tuberculosis Rv1559 SW:THD1_MYCT and Corynebacterium glutamicum SW:THD1_CORGL (Q04513) (436 aa), Fasta scores: E(): 0, 60.7% identity in 415 aa overlap. Contains Pfam match to entry PF00585 Thr_dehydrat_C, C-terminal domain of Threonine dehydratase. Contains Pfam match to entry PF00291 S_T_dehydratase, Pyridoxal-phosphate dependent enzyme. Contains PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.;UniProt_AC=Q9X7F1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1175024	1175731	.	-	0	Locus=ML1003c;Name=lexA;Function=INVOLVED IN REGULATION OF NUCLEOTIDE EXCISION REPAIR AND SOS RESPONSE. REPRESSES A NUMBER OF GENES INVOLVED IN THE RESPONSE TO DNA DAMAGE (SOS RESPONSE), INCLUDING RECA AND LEXA. HAS BEEN SHOWN TO BIND TO THE 14 BP PALINDROMIC SEQUENCE 5'-CGAACNNNNGTTCG-3'. IN THE PRESENCE OF SINGLE-STRANDED DNA, RECA INTERACTS WITH LEXA CAUSING AN AUTOCATALYTIC CLEAVAGE WHICH DISRUPTS THE DNA-BINDING PART OF LEXA, LEADING TO DEREPRESSION OF THE SOS REGULON AND EVENTUALLY DNA REPAIR [CATALYTIC ACTIVITY: HYDROLYSIS OF ALA-|-GLY BOND IN REPRESSOR LEXA].;Product=REPRESSOR LEXA;Comments=ML1003c, len: 235 aa. Probable lexA, repressor (EC 3.4.21.88). Identical to the previously sequenced Mycobacterium leprae LexA protein TR:Q49848 (EMBL:U00019) (235 aa), Fasta scores: E(): 0, 100.0% identity in 235 aa overlap. Also highly similar to many other LexA proteins known to repress genes in response to DNA damage, as part of the SOS response e.g. from Mycobacterium tuberculosis Rv2720 TR:Q50765 (EMBL:X91407) (217 aa), Fasta scores: E(): 0, 89.4% identity in 218 aa overlap and Escherichia coli SW:LEXA_ECOLI (P03033) (202 aa), Fasta scores: E(): 2.3e-10, 33.5% identity in 215 aa overlap. Note codon 19 represents an alternative possible translational start site. Contains Pfam match to entry PF00717 Peptidase_S24, Peptidase family S24. Contains Pfam match to entry PF01726 LexA_DNA_bind, LexA DNA binding domain.;UniProt_AC=Q49848;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1005909	1008083	.	+	0	Locus=ML0848;Name=ML0848;Function=;Product=POSSIBLE TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSORTER;Comments=ML0848, len: 724 aa. Possible transmembrane ATP-binding protein ABC transporter.  Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv2326c or MTCY3G12.08 SW:YN26_MYCTU (P71886) (697 aa) fasta scores: E(): 0, 76.9% identity in 697 aa. Shares similar domains with many ABC-type transporters e.g. Streptomyces roseofulvus ATPase component of putative ABC transporter frnD TR:O68910 (EMBL:AF058302) (524 aa) fasta scores: E(): 8.4e-14, 31.5% identity in 495 aa and Synechococcus sp. nitrate transport ATP-binding protein NrtD nrtD SW:NRTD_SYNP7 (P38046) (274 aa) fasta scores: E(): 1.6e-12, 34.8% identity in 198 aa. Previously sequenced as TR:O32971 (EMBL:Z98741). Contains hydrophobic, possible membrane-spanning regions. Contains 2 Pfam matches to entry PF00005 ABC_tran, ABC transporter. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop). Contains 2 x PS00211 ABC transporters family signature. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).;UniProt_AC=Q9CCF9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1163318	1164253	.	+	0	Locus=ML0995;Name=miaA;Function=CATALYZES THE FIRST STEP IN THE BIOSYNTHESIS OF 2-METHYLTHIO-N6-(DELTA(2)-ISOPENTENYL)-ADENOSINE (MS[2]I[6]A]) ADJACENT TO THE ANTICODON OF SEVERAL TRNA SPECIES [CATALYTIC ACTIVITY: ISOPENTENYL DIPHOSPHATE + TRNA = PYROPHOSPHATE + TRNA CONTAINING 6-ISOPENTENYLADENOSINE].;Product=PROBABLE TRNA DELTA(2)-ISOPENTENYLPYROPHOSPHATE TRANSFERASE MIAA (IPP TRANSFERASE) (ISOPENTENYL-DIPHOSPHATE:TRNA ISOPENTENYLTRANSFERASE) (IPTASE) (IPPT);Comments=ML0995, len: 311 aa. Probable miaA, tRNA delta(2)-isopentenylpyrophosphate transferase (EC 2.5.1.8) . Identical to the previously sequenced Mycobacterium leprae tRNA delta(2)-isopentenylpyrophosphate transferase (EC 2.5.1.8) SW:MIAA_MYCLE (P46811) (311 aa), Fasta scores: E(): 0, 100.0% identity in 311 aa overlap, as well as several other IPP transferases e.g. from Mycobacterium tuberculosis SW:MIAA_MYCTU (O33232) (314 aa), Fasta scores: E(): 0, 82.2% identity in 314 aa overlap and Escherichia coli SW:MIAA_ECOLI (P16384) (316 aa), Fasta scores: E(): 2.2e-27, 35.5% identity in 293 aa overlap. Contains Pfam match to entry PF01715 IPPT, IPP transferase. Belongs to the IPP transferase family.;UniProt_AC=P46811;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1155734	1157287	.	+	0	Locus=ML0989;Name=ML0989;Function=;Product=CONSERVED HYPOTHETICAL ALANINE, ARGININE-RICH PROTEIN;Comments=ML0989, len: 517 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YR33_MYCLE (Q49842) (516 aa), Fasta scores: E(): 0, 99.8% identity in 516 aa overlap. Also highly similar to many other proteins of undefined function belonging to the the Pfam UPF0004 family, including: Mycobacterium tuberculosis Rv2733c SW:YR33_MYCTU (O33238) (512 aa), Fasta scores: E(): 0, 80.4% identity in 509 aa overlap and Bacillus subtilis YMCB_BACSU. Contains Pfam match to entry PF00919 UPF0004, Uncharacterized protein family UPF0004. Contains PS01278 Uncharacterized protein family UPF0004 signature. Belongs to the UPF0004 family. ;UniProt_AC=Q49842;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1266651	1270109	.	-	0	Locus=ML1098c;Name=ML1098c;Function=;Product=conserved hypothetical protein;Comments=ML1098c, len: 1152 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1251c TR:O50466 (EMBL:AL021006) (1139 aa), Fasta scores: E(): 0, 75.5% identity in 1141 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CC95;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1287740	1289629	.	-	0	Locus=ML1113c;Name=ML1113c;Function=;Product=PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER;Comments=ML1113c, len: 629 aa. Probable drugs-transport transmembrane ATP-binding protein ABC transporter. Highly similar to many proposed ABC transporter proteins including: Mycobacterium tuberculosis Rv1272c YC72_MYCTU (Q11047) (631 aa), Fasta scores: E(): 0, 75.4% identity in 623 aa overlap and Bacillus subtilis hypothetical ABC transporter ATP-binding protein SW:YFIC_BACSU (P54719) (604 aa), Fasta scores: E(): 0, 43.2% identity in 532 aa overlap. Also similar to the adjoining CDS ML1114. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.;UniProt_AC=Q9CC89;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1462236	1465187	.	+	0	Locus=ML1231;Name=mmpL10;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL10;Comments=ML1231, len: 983 aa. Probable mmpL10, conserved transmembrane transport protein. Previously sequenced Mycobacterium leprae membrane protein MMPL10 SW:MMLA_MYCLE (Q49619) (1008 aa), Fasta scores: E(): 0, 100.0% identity in 983 aa overlap. Also highly similar to many MMPL-family Mycobacterium tuberculosis proteins e.g. Rv1183 SW:MMLA_MYCTU (O50439) (1002 aa), Fasta scores: E(): 0, 70.4% identity in 978 aa overlap. Also similar to ML2378 and ML0137 from M. leprae. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q49619;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1243758	1244909	.	-	0	Locus=ML1080c;Name=mrp;Function=;Product=PROBABLE MRP-RELATED PROTEIN MRP;Comments=ML1080c, len: 383 aa. Probable Mrp protein. Previously sequenced Mycobacterium leprae SW:MRP_MYCLE (P53382) (435 aa), Fasta scores: E(): 0, 100.0% identity in 383 aa overlap. Similar to many other MRP-family proteins, the function of which is unknown, e.g. Mycobacterium tuberculosis Rv1229c SW:MRP_MYCTU (O33225) (390 aa), Fasta scores: E(): 0, 82.1% identity in 374 aa overlap and Escherichia coli SW:MRP_ECOLI (P21590) (379 aa), Fasta scores: E(): 8.3e-30, 33.3% identity in 360 aa overlap. Contains Pfam match to entry PF01883 DUF59, Domain of unknown function. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS01215 Mrp family signature. BELONGS TO THE MRP/NBP35 FAMILY OF ATP-BINDING PROTEINS.;UniProt_AC=P53382;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2758991	2759683	.	+	0	Locus=ML2327;Name=cobQ2;Function=;Product=POSSIBLE COBYRIC ACID SYNTHASE COBQ2;Comments=ML2327, len: 230 aa. Possible cobQ2, cobyric acid synthase. Similar to Mycobacterium tuberculosis cobQ2, cobyric acid synthase Rv3713 TR:O69680 (EMBL:AL022121) (231 aa) fasta scores: E(): 0, 86.5% identity in 230 aa. Also weakly similar to others e.g. Pseudomonas denitrificans cobB SW:COBB_PSEDE (P21632) (433 aa) fasta scores: E(): 0.0027, 30.7% identity in 166 aa. Contains Pfam match to entry PF01656 CBIA, Cobyrinic acid a,c-diamide synthase.;UniProt_AC=O69521;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1339583	1340839	.	+	0	Locus=ML1150;Name=murA;Function=;Product=PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA;Comments=ML1150, len: 418 aa. Probable murA, UDP-N-acetylglucosamine-1-carboxyvinyltransferase (EC 2.5.1.7). Identical to the previously sequenced Mycobacterium leprae UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) SW:MURA_MYCLE (P45821) (418 aa), Fasta scores: E(): 0, 99.8% identity in 418 aa overlap representing the first step in peptidoglycan biosynthesis. Also highly similar to many other UDP-N-acetylglucosamine 1-carboxyvinyltransferases e.g. Mycobacterium tuberculosis Rv1315 SW:MURA_MYCTU (Q10604) (418 aa), Fasta scores: E(): 0, 95.9% identity in 417 aa overlap and Escherichia coli SW:MURA_ECOLI (P2890) (419 aa), Fasta scores: E(): 0, 45.7% identity in 416 aa overlap. Contains Pfam match to entry PF00275 EPSP_syntase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase).;UniProt_AC=P45821;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1016252	1017526	.	+	0	Locus=ML0855;Name=pepR;Function=;Product=PROBABLE ZINC PROTEASE PEPR;Comments=ML0855, len: 424 aa. Probable pepR, protease/peptidase (EC 3.4.99.-). Similar to Mycobacterium tuberculosis hypothetical zinc protease Rv2782c or MTV002.47C SW:YR82_MYCTU (O33324) (438 aa) fasta scores: E(): 0, 84.3% identity in 421 aa and to others, both bacterial and eukaryotic e.g. Homo sapiens mitochondrial processing peptidase beta subunit precursor pmpcB or mppB SW:MPPB_HUMAN (O75439) (489 aa) fasta scores: E(): 0, 30.6% identity in 434 aa. Previously sequenced as SW:YR82_MYCLE (O32965). Contains Pfam match to entry PF00675 Peptidase_M16, Insulinase (Peptidase family M16). Contains PS00143 Insulinase family, zinc-binding region signature. BELONGS TO PEPTIDASE FAMILY M16, ALSO KNOWN AS THE INSULINASE FAMILY. COFACTOR: REQUIRES DIVALENT CATIONS FOR ACTIVITY. BINDS ZINC.;UniProt_AC=O32965;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1062991	1064193	.	-	0	Locus=ML0897c;Name=pknL;Function=;Product=PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE L PKNL (PROTEIN KINASE L) (STPK L);Comments=ML0897c, len: 400 aa. Probable pknL, transmembrane serine/threonine-protein kinase (EC 2.7.1.-).  Identical to the previously sequenced Mycobacterium leprae putative serine/threonine protein kinase TR:O69568 (EMBL:AL022602) (400 aa), Fasta scores: E(): 0, 99.8% identity in 400 aa overlap. Also highly similar to many other putative serine/threonine protein kinases e.g. from Mycobacterium tuberculosis: Rv2176 TR:O53510 (EMBL:AL021957) (399 aa), Fasta scores: E(): 0, 75.3% identity in 400 aa overlap and SW:PKNB_MYCTU (SW:P71584) (626 aa), Fasta scores: E(): 2e-31, 39.5% identity in 311 aa overlap. Also similar to ML0016 and ML0017 from M. leprae. Contains Pfam match to entry PF00069 pkinase, Eukaryotic protein kinase domain. Contains PS00108 Serine/Threonine protein kinases active-site signature. Contains PS00107 Protein kinases ATP-binding region signature. BELONGS TO THE SER/THR FAMILY OF PROTEIN KINASES;UniProt_AC=O69568;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1184333	1185292	.	-	0	Locus=ML1014c;Name=sigB;Function=THE SIGMA FACTOR IS AN INITIATION FACTOR THAT PROMOTES ATTACHMENT OF THE RNA POLYMERASE TO SPECIFIC INITIATION SITES AND THEN IS RELEASED. MAY CONTROL THE REGULONS OF STATIONARY PHASE AND GENERAL STRESS RESISTANCE. IN M. TUBERCULOSIS IT SEEMS TO BE REGULATED BY SIGH AND SIGE. SEEMS TO REGULATE KATG AND THE HEAT-SHOCK RESPONSE;Product=RNA polymerase principal sigma factor SigB;Comments=ML1014c, len: 319 aa. Probable sigB, RNA polymerase sigma factorIdentical to the previously sequenced Mycobacterium leprae RNA polymerase sigma factor TR:Q59531 (EMBL:U15181) (319 aa), Fasta scores: E(): 0, 100.0% identity in 319 aa overlap. Also highly similar to many Sigma-70 family proteins e.g. Mycobacterium tuberculosis Rv2710 TR:Q59563 (EMBL:U10059) (323 aa), Fasta scores: E(): 0, 96.2% identity in 316 aa overlap and Streptomyces coelicolor SW:HRDB_STRCO (P18183) (442 aa), Fasta scores: E(): 0, 60.7% identity in 303 aa overlap. Highly similar to the C-terminus of ML1022 from M. leprae. Contains a putative helix-turn-helix motif situated between residues 278..299 (+5.61 SD). Contains a probable helix-turn-helix motif at aa 278-299 (Score 1887, SD +5.61) Contains Pfam match to entry PF00140 sigma70, Sigma-70 factor. Contains PS00716 Sigma-70 factors family signature 2. Contains PS00715 Sigma-70 factors family signature 1. BELONGS TO THE SIGMA-70 FACTOR FAMILY.;UniProt_AC=Q59531;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2046991	2047824	.	-	0	Locus=ML1698c;Name=ML1698c;Function=;Product=conserved membrane protein;Comments=ML1698c, len: 277 aa. Conserved membrane protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv3005c TR:O53252 (EMBL:AL021287) (279 aa), Fasta scores: E(): 0, 68.7% identity in 278 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=O33110;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1319645	1320970	.	+	0	Locus=ML1129;Name=thrA;Function=INVOLVED IN THE CONVERSION OF L-ASPARTATE TO HOMOSERINE (THIRD STEP). HOMOSERINE PARTICIPATES IN THE BIOSYNTHESIS OF THREONINE AND THEN ISOLEUCINE AND IN THE BIOSYNTHESIS OF METHIONINE  [CATALYTIC ACTIVITY : L-HOMOSERINE + NAD(P)(+) = L-ASPARTATE 4-SEMIALDEHYDE + NAD(P)H.];Product=PROBABLE HOMOSERINE DEHYDROGENASE THRA;Comments=ML1129, len: 441 aa. Probable thrA (hom), homoserine dehydrogenase (EC 1.1.1.3). Identical to the previously sequenced Mycobacterium leprae homoserine dehydrogenase SW:DHOM_MYCLE (P46806) (441 aa), Fasta scores: E(): 0, 99.8% identity in 441 aa overlap. Also highly similar to orthologues from Mycobacterium tuberculosis SW:DHOM_MYCTU (Q10601) (441 aa), Fasta scores: E(): 0, 89.5% identity in 438 aa overlap and Corynebacterium glutamicum SW:DHOM_CORGL (P08499) (445 aa), Fasta scores: E(): 0, 60.3% identity in 431 aa overlap. Contains Pfam match to entry PF00742 Homoserine_dh, Homoserine dehydrogenase. Contains Pfam match to entry PF01842 ACT, ACT domain. Contains PS01042 Homoserine dehydrogenase signature.;UniProt_AC=P46806;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1512142	1513731	.	+	0	Locus=ML1269;Name=trpE;Function=Possibly involved in biosynthesis of tryptophan (at the first step).  Supposed tetramer of two components I and two components II: component I (ML1269|trpE) catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II (ML0015|trpG) provides glutamine aminotranferase activity. Possibly participates in the tryptophan-dependent indole-3-acetic acid production [Catalytic activity: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate]. ;Product=Probable anthranilate synthase component I TrpE (GLUTAMINE AMIDOTRANSFERASE);Comments=ML1269, len: 529 aa. Probable trpE, anthranilate synthase component I (EC 4.1.3.27). Highly similar to many anthranilate synthase component I family proteins involved in tryptophan biosynthesis e.g. Mycobacterium tuberculosis Rv1609 SW:TRPE_MYCTU (O06127) (516 aa), Fasta scores: E(): 0, 88.0% identity in 508 aa overlap and Pseudomonas putida SW:TRPE_PSEPU (P20579) (493 aa), Fasta scores: E(): 0, 44.4% identity in 504 aa overlap. Contains Pfam match to entry PF00425 chorismate_bind, chorismate binding enzyme.;UniProt_AC=Q9X7C5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1690893	1692107	.	+	0	Locus=ML1409;Name=argD;Function=;Product=Probable Acetylornithine aminotransferase ArgD;Comments=ML1409, len: 404 aa. Probable argD, Acetylornithine aminotransferase (EC 2.6.1.11). Highly similar to many acetylornithine aminotransferases (EC 2.6.1.11) involved in arginine biosynthesis, including: Escherichia coli SW:ARGD_ECOLI (P18335) (405 aa), Fasta scores: E(): 0, 38.7% identity in 390 aa overlap and Mycobacterium tuberculosis Rv1655 SW:ARGD_MYCTU (P94990) (400 aa), Fasta scores: E(): 0, 82.9% identity in 397 aa overlap. Contains Pfam match to entry PF00202 aminotran_3, Aminotransferases class-III pyridoxal-phosphate. Contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. Belongs to class-III of pyridoxal-phosphate-dependent aminotransferases.;UniProt_AC=Q9CC12;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1762675	1764114	.	-	0	Locus=ML1465c;Name=obg;Function=;Product=PROBABLE GTP1/OBG-FAMILY GTP-BINDING PROTEIN OBG;Comments=ML1465c, len: 479 aa. Probable obg, nucleotide-binding protein. Highly similar to several proposed GTP-binding proteins including: Escherichia coli SW:YHBZ_ECOLI (P42641) (390 aa), Fasta scores: E(): 0, 41.6% identity in 353 aa overlap and Mycobacterium tuberculosis hypothetical protein Rv2440c SW:P71909. Contains Pfam match to entry PF01018 GTP1_OBG, GTP1/OBG family. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CBZ4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1536153	1537556	.	+	0	Locus=ML1288;Name=ML1288;Function=;Product=possible peptidase;Comments=ML1288, len: 467 aa. Possible peptidase. Similar to several members of the ARGE/DAPE/ACY1 protein family including: Mycobacterium tuberculosis Rv2141c, TR:O06234 (EMBL:Z95388) (448 aa), Fasta scores: E(): 0, 83.9% identity in 448 aa overlap and Streptomyces coelicolor putative aminoacylase TR:Q9ZBI7 (EMBL:AL035161) (443 aa), Fasta scores: E(): 0, 47.6% identity in 433 aa overlap). Contains Pfam match to entry PF01546 Peptidase_M20, Peptidase family M20/M25/M40. Contains PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.;UniProt_AC=Q9CC46;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1546120	1546968	.	+	0	Locus=ML1297;Name=ML1297;Function=;Product=Possible conserved transmembrane protein;Comments=ML1297, len: 282 aa. Possible conserved transmembrane protein. Similar to Mycobacterium tuberculosis Rv2136c TR:O06239 (EMBL:Z95388) (276 aa), Fasta scores: E(): 0, 82.6% identity in 276 aa overlap. Also similar to several proposed undecaprenol kinases or bacitracin resistance proteins including: Escherichia coli SW:BACA_ECOLI (P31054) (273 aa), Fasta scores: E(): 3.7e-23, 34.0% identity in 265 aa overlap and  Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CC42;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1543268	1544341	.	-	0	Locus=ML1293c;Name=pyrD;Function=;Product=Probable dihydroorotate dehydrogenase PyrD;Comments=ML1293c, len: 357 aa. Probable pyrD, dihydroorotate dehydrogenase (EC 1.3.3.1). Highly similar to many dihydroorotate dehydrogenases involved in pyrimidine biosynthesis, including: Escherichia coli PyrD SW:PYRD_ECOLI (P05021) (336 aa), Fasta scores: E(): 0, 42.3% identity in 333 aa overlap and Mycobacterium tuberculosis PyrD Rv2139 SW:PYRD_MYCTU (O06236) (357 aa), Fasta scores: E(): 0, 80.9% identity in 351 aa overlap. Contains Pfam match to entry PF01180 DHOdehase, Dihydroorotate dehydrogenase. Contains PS00912 Dihydroorotate dehydrogenase signature 2. Contains PS00911 Dihydroorotate dehydrogenase signature 1.;UniProt_AC=P46727;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1552523	1554019	.	-	0	Locus=ML1304c;Name=ansP1;Function=;Product=POSSIBLE L-ASPARAGINE PERMEASE ANSP1 (L-ASPARAGINE TRANSPORT PROTEIN);Comments=ML1304c, len: 498 aa. Probable ansP1, L-asparagine permeas. Highly similar to many L-asparagine transport proteins including: Salmonella typhimurium AnsP SW:ANSP_SALTY (P40812) (497 aa), Fasta scores: E(): 0, 58.7% identity in 477 aa overlap and Mycobacterium tuberculosis Rv2127 SW:ANSP_MYCTU (O33261) (489 aa), Fasta scores: E(): 0, 83.4% identity in 488 aa overlap and O06297|Rv0346c Possible ansP2, L-asparagine permease (487 aa), fasta scores: E(): 5.5e-129, (69.556% identity in 473 aa overlap). Almost identical to the duplicated sequence ML1305. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00324 aa_permeases, Amino acid permease. Contains PS00218 Amino acid permeases signature.;UniProt_AC=Q49801;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1759309	1761351	.	-	0	Locus=ML1463c;Name=nadE;Function=;Product=PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]);Comments=ML1463c, len: 680 aa. Probable nadE, glutamine-dependent NAD(+) synthetase (EC 6.3.5.1). Highly similar to several e.g. Rhodobacter capsulatus SW:NADE_RHOCA (Q03638) (552 aa), Fasta scores: E(): 3.6e-11, 24.9% identity in 579 aa overlap glutamine-dependent NAD(+) synthetase and Mycobacterium tuberculosis Rv2438c TR:P71911 (EMBL:Z81451) (679 aa), Fasta scores: E(): 0, 84.4% identity in 679 aa overlap. Contains Pfam match to entry PF00795 CN_hydrolase, Carbon-nitrogen hydrolase. Contains PS00591 Glycosyl hydrolases family 10 active site. BELONGS TO THE NAD SYNTHETASE FAMILY IN THE C-TERMINAL SECTION.;UniProt_AC=Q9CBZ6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1579805	1581163	.	+	0	Locus=ML1328;Name=paf;Function=;Product=Probable proteasome associated factor Paf;Comments=ML1328, len: 452 aa. Probable paf, proteasome associated factor (see Darwin et al., 2003). Highly similar to Mycobacterium tuberculosis Rv2097c SW:YK97_MYCTU (Q10706) paf, proteasome associated factor (452 aa), Fasta scores: E(): 0, 94.9% identity in 452 aa overlap. And many proteins of unknown function including: Rhodococcus erythropolis TR:P72263 (EMBL:Z82004) (447 aa), Fasta scores: E(): 0, 89.3% identity in 447 aa overlap. Contains a putative helix-turn-helix motif situated between residues 380..401 (+3.12 SD). Contains a probable helix-turn-helix motif at aa 380-401 (Score 1155, SD +3.12).;UniProt_AC=P54077;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1583188	1583475	.	+	0	Locus=ML1331;Name=tatA;Function=INVOLVED IN PROTEINS EXPORT: REQUIRED FOR CORRECT LOCALIZATION OF PRECURSOR PROTEINS BEARING SIGNAL PEPTIDES WITH THE TWIN ARGININE CONSERVED MOTIF S/T-R-R-X-F-L-K. THIS SEC-INDEPENDENT PATHWAY IS TERMED TAT FOR TWIN-ARGININE TRANSLOCATION SYSTEM. THIS SYSTEM MAINLY TRANSPORTS PROTEINS WITH BOUND COFACTORS THAT REQUIRE FOLDING PRIOR TO EXPORT.;Product=PROBABLE SEC-INDEPENDENT PROTEIN TRANSLOCASE MEMBRANE-BOUND PROTEIN TATA;Comments=ML1331, len: 95 aa. Probable tatA, membrane-bound protein, component of twin-arginine translocation protein export system (see Berks et al., 2000). Highly similar to others e.g. Streptomyces coelicolor putative secreted protein TR:Q9RJ68 (EMBL:AL132648) (95 aa), Fasta scores: E(): 5.1e-09, 45.3% identity in 86 aa overlap and Mycobacterium tuberculosis Rv2094c SW:YK94_MYCTU (Q10703) (83 aa), Fasta scores: E(): 5.2e-21, 68.2% identity in 88 aa overlap. Contains a possible N-terminal signal sequence. Note codon 8 may offer an alternative translational start site. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE TATA/E FAMILY.;UniProt_AC=P54079;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1595453	1596775	.	-	0	Locus=ML1338c;Name=ML1338c;Function=;Product=possible conserved integral membrane protein;Comments=ML1338c, len: 440 aa. Possible conserved integral membrane protein. Similar to several membrane proteins e.g. Mycobacterium tuberculosis Rv2673 TR:P71970 (EMBL:Z80225) (433 aa), Fasta scores: E(): 0, 82.0% identity in 434 aa overlap and weakly similar to Streptomyces coelicolor TR:Q53873 (EMBL:AL031317) (411 aa), Fasta scores: E(): 1.1e-12, 28.3% identity in 410 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=O05686;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1611524	1612168	.	+	0	Locus=ML1351;Name=mpg;Function=;Product=POSSIBLE 3-METHYLADENINE DNA GLYCOSYLASE MPG;Comments=ML1351, len: 214 aa. Possible mpg, 3-methylpurine DNA glycosylase (EC 3.2.2.-). Similar to several DNA-3-methyladenine glycosylases from both Prokaryotes and Eukaryotes e.g. Bacillus subtilis SW:3MGH_BACSU (P94378) (196 aa), Fasta scores: E(): 7.7e-13, 38.4% identity in 185 aa overlap and Arabidopsis thaliana SW:3MG_ARATH (Q39147) (254 aa), Fasta scores: E(): 1.1e-11, 32.0% identity in 194 aa overlap. Also highly similar to Mycobacterium tuberculosis Rv1688 putative 3-methyladenine DNA glycosylase SW:3MGH_MYCTU (O33190) (203 aa), Fasta scores: E(): 0, 78.3% identity in 203 aa overlap. Note codon 12 may offer an alternative translational start site.;UniProt_AC=O05678;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1624156	1625928	.	+	0	Locus=ML1363;Name=pyrG;Function=;Product=Probable CTP synthase PyrG;Comments=ML1363, len: 590 aa. Probable pyrG, CTP synthase (EC 6.3.4.2). Highly similar to many CTP synthases, catalysing the last step in pyrimidine biosynthesis, including: Escherichia coli SW:PYRG_ECOLI (P08398) (544 aa), Fasta scores: E(): 0, 50.5% identity in 548 aa overlap and Mycobacterium tuberculosis Rv1699 SW:PYRG_MYCTU (P96351) (586 aa), Fasta scores: E(): 0, 89.2% identity in 590 aa overlap. Contains Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I. Contains PS00442 Glutamine amidotransferases class-I active site.;UniProt_AC=P53529;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1626542	1627492	.	+	0	Locus=ML1365;Name=ML1365;Function=;Product=PROBABLE INTEGRASE/RECOMBINASE;Comments=ML1365, len: 316 aa. Probable integrase/recombinase. Highly similar to several including: Escherichia coli integrase/recombinase XerD which is involved in site specific recombination, SW:XERD_ECOLI (P21891) (298 aa), Fasta scores: E(): 5.7e-29, 40.3% identity in 308 aa overlap. Also similar to several other Mycobacterium tuberculosis integrase/recombinases e.g. Rv1701 TR:O33200 (EMBL:Z98268) (311 aa), Fasta scores: E(): 0, 85.9% identity in 311 aa overlap and Rv2894c SW:YS94_MYCTU (Q10815) (298 aa), Fasta scores: E(): 0, 42.9% identity in 312 aa overlap. Also similar to ML1365 from M. leprae. Contains Pfam match to entry PF00589 Phage_integrase, 'Phage' integrase family.;UniProt_AC=Q49890;Is_Pseudogene=No;Functional_Category=insertion seqs and phages
AL450380.2	Mycobrowser_v2	CDS	1652732	1654177	.	+	0	Locus=ML1382;Name=rpsA;Function=;Product=PROBABLE RIBOSOMAL PROTEIN S1 RPSA;Comments=ML1382, len: 481 aa. Probable rpsA, 30S ribosomal protein S1. Highly similar to multiple 30S ribosomal proteins S1 including: Escherichia coli SW:RS1_ECOLI (P02349) (557 aa), Fasta scores: E(): 0, 39.1% identity in 471 aa overlap and Mycobacterium tuberculosis Rv1630 SW:RS1_MYCTU (O06147) (481 aa), Fasta scores: E(): 0, 93.8% identity in 481 aa overlap. Previously sequenced SW:RS1_MYCLE (P46836) (482 aa), Fasta scores: E(): 0, 93.2% identity in 483 aa overlap. Contains 4 Pfam matches to entry PF00575 S1, S1 RNA binding domain.;UniProt_AC=P46836;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1665178	1666761	.	-	0	Locus=ML1389c;Name=ML1389c;Function=;Product=Probable conserved transmembrane protein;Comments=ML1389c, len: 527 aa. Probable conserved transmembrane protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1635c TR:O06152 (EMBL:Z95554) (556 aa), Fasta scores: E(): 0, 71.6% identity in 528 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Also similar to ML2515 a possible pseudogene similar to M. tuberculosis Rv1635c.;UniProt_AC=Q9CC27;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1629747	1630442	.	+	0	Locus=ML1369;Name=scpB;Function=;Product=conserved hypothetical protein;Comments=ML1369, len: 231 aa. Conserved hypothetical protein. Similar to many proteins of undefined function e.g. Streptomyces coelicolor TR:Q9S231 (EMBL:AL109848) (223 aa), Fasta scores: E(): 0, 54.5% identity in 187 aa overlap and Mycobacterium tuberculosis Rv1710 TR:O33209 (EMBL:Z98268) (231 aa), Fasta scores: E(): 0, 77.9% identity in 231 aa overlap.;UniProt_AC=O05669;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1692181	1693101	.	+	0	Locus=ML1410;Name=argF;Function=;Product=Probable Ornithine carbamoyltransferase, anabolic ArgF;Comments=ML1410, len: 306 aa. Probable argF, Ornithine carbamoyltransferase (EC 2.1.3.3). Highly similar to many ornithine carbamoyltransferase involved in arginine biosynthesis, including: Bacillus subtilis SW:OTCA_BACSU (P18186) (319 aa), Fasta scores: E(): 0, 48.0% identity in 304 aa overlap and Mycobacterium tuberculosis Rv1656 SW:OTCA_MYCTU (P94991) (307 aa), Fasta scores: E(): 0, 85.0% identity in 306 aa overlap. Start changed, was originally 15 codons upstream. Contains Pfam match to entry PF00185 OTCace, Aspartate/ornithine carbamoyltransferase. Contains PS00097 Aspartate and ornithine carbamoyltransferases signature.;UniProt_AC=Q9CC11;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1711570	1712640	.	-	0	Locus=ML1424c;Name=ML1424c;Function=;Product=Probable sugar-transport ATP-binding protein ABC transporter;Comments=ML1424c, len: 356 aa. Probable sugar-transport ATP-binding protein ABC transporter. Highly similar to several binding-protein-dependent transport proteins including: Escherichia coli SN-glycerol-3-phosphate transport ATP-binding protein SW:UGPC_ECOLI (P10907) (356 aa), Fasta scores: E(): 0, 47.9% identity in 363 aa overlap and Mycobacterium tuberculosis ABC-type sugar transport protein Rv2038c TR:O53482 (EMBL:AL021899) (357 aa), Fasta scores: E(): 0, 79.7% identity in 355 aa overlap. Also similar to ML1089, ML0669 and ML1892 from M. leprae. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.;UniProt_AC=O32942;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1712643	1713494	.	-	0	Locus=ML1425c;Name=ML1425c;Function=;Product=Probable sugar-transport integral membrane protein ABC transporter;Comments=ML1425c, len: 283 aa. Probable sugar-transport integral membrane protein ABC transporter. Highly similar to many putative ABC_transport proteins e.g. Mycobacterium tuberculosis sugar transport protein Rv2039c TR:O53483 (EMBL:AL021899) (280 aa), Fasta scores: E(): 0, 79.2% identity in 283 aa overlap. Also similar to ML2039c from M. leprae. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign.;UniProt_AC=O32941;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1714437	1715774	.	-	0	Locus=ML1427c;Name=ML1427c;Function=;Product=Probable sugar-binding lipoprotein;Comments=ML1427c, len: 445 aa. Probable sugar-binding lipoprotein. Similar to several putative ABC_transport proteins e.g. Mycobacterium tuberculosis lipoprotein component of sugar transport system  Rv2041c TR:O53485 (EMBL:AL021899) (439 aa), Fasta scores: E(): 0, 77.4% identity in 446 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=O32939;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1751755	1752984	.	-	0	Locus=ML1458c;Name=proA;Function=INVOLVED IN PROLINE BIOSYNTHESIS PATHWAY (AT THE SECOND STEP). CATALYZES THE NADPH DEPENDENT REDUCTION OF L-GAMMA- GLUTAMYL 5-PHOSPHATE INTO L-GLUTAMATE 5-SEMIALDEHYDE AND PHOSPHATE. THE PRODUCT SPONTANEOUSLY UNDERGOES CYCLIZATION TO FORM 1-PYRROLINE-5-CARBOXYLATE. [CATALYTIC ACTIVITY: L-GLUTAMATE 5-SEMIALDEHYDE + PHOSPHATE + NADP(+) = L-GAMMA-GLUTAMYL 5-PHOSPHATE + NADPH].;Product=PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDEHYDE DEHYDROGENASE);Comments=ML1458c, len: 409 aa. Probable proA, gamma-glutamyl phosphate reductase protein (EC 1.2.1.41). Highly similar to many gamma-glutamyl phosphate reductases involved in proline biosynthesis, e.g. Bacillus subtilis SW:PROA_BACSU (P39821) (415 aa), Fasta scores: E(): 0, 47.3% identity in 412 aa overlap and Mycobacterium tuberculosis Rv2427c SW:PROA_MYCTU (P71921) (415 aa), Fasta scores: E(): 0, 82.2% identity in 409 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase family. Contains PS01223 Gamma-glutamyl phosphate reductase signature. BELONGS TO THE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE FAMILY.;UniProt_AC=Q9CBZ7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1765045	1767819	.	-	0	Locus=ML1468c;Name=rne;Function=;Product=possible ribonuclease E Rne;Comments=ML1468c, len: 924 aa. Possible rne, ribonuclease (EC 3.1.-.-). Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E SW:RNE_ECOLI (P21513) (1061 aa), Fasta scores: E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis Rv2444c TR:P71905 (EMBL:Z81451) (953 aa), Fasta scores: E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain.;UniProt_AC=Q9CBZ1;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1764229	1764495	.	-	0	Locus=ML1466c;Name=rpmA;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L27 RPMA;Comments=ML1466c, len: 88 aa. Probable rpmA, 50S ribosomal protein L27. Highly similar to many 50s ribosomal proteins (L27) including: Escherichia coli SW:RL27_ECOLI (P02427) (84 aa), Fasta scores: E(): 5.8e-16, 63.9% identity in 83 aa overlap and Mycobacterium tuberculosis Rv2441c SW:RL27_MYCTU (Z8145) (86 aa), Fasta scores: E(): 3.3e-28, 93.8% identity in 81 aa overlap. Contains Pfam match to entry PF01016 Ribosomal_L27, Ribosomal L27 protein. Contains PS00831 Ribosomal protein L27 signature.;UniProt_AC=Q9CBZ3;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1768990	1770447	.	-	0	Locus=ML1471c;Name=folC;Function=CONVERSION OF FOLATES TO POLYGLUTAMATE DERIVATIVES. BACTERIA REQUIRE FOLATE FOR THE BIOSYNTHESIS OF GLYCINE, METHIONINE, FORMYL-MET-TRNA, THYMIDYLATES, PURINES, AND PANTOTHENATE [CATALYTIC ACTIVITY: ATP + {TETRAHYDROFOLYL-[GLU]}(N) + L-GLUTAMATE = ADP + PHOSPHATE + {TETRAHYDROFOLYL-[GLU]}(N+1)].;Product=PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS);Comments=ML1471c, len: 485 aa. Probable folC, folylpolyglutamate synthase (EC 6.3.2.17). Highly similar to many folylpolyglutamate synthases including: Lactobacillus casei SW:FOLC_LACCA (P15925) (428 aa), Fasta scores: E(): 0, 34.1% identity in 437 aa overlap and Mycobacterium tuberculosis Rv2447c TR:O53174 (EMBL:AL021246) (487 aa), Fasta scores: E(): 0, 78.7% identity in 483 aa overlap. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family. Contains PS01012 Folylpolyglutamate synthase signature 2. BELONGS TO THE FOLYLPOLYGLUTAMATE SYNTHASE FAMILY.;UniProt_AC=Q9CBY8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1787919	1788542	.	-	0	Locus=ML1485c;Name=ML1485c;Function=;Product=conserved hypothetical protein;Comments=ML1485c, len: 207 aa. Conserved hypothetical protein. Highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis Rv2466c TR:O53193 (EMBL:AL02124) (207 aa), Fasta scores: E(): 0, 80.6% identity in 206 aa overlap and Streptomyces coelicolor TR:CAB71809 (EMBL:AL138662) (216 aa), Fasta scores: E(): 0, 52.3% identity in 214 aa overlap.;UniProt_AC=Q9CBY0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1783575	1784984	.	-	0	Locus=ML1481c;Name=tig;Function=;Product=PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG;Comments=ML1481c, len: 469 aa. Probable tig, trigger factor (TF), a chaperone protein. Highly similar to many including: Escherichia coli trigger factor Tig, SW:TIG_ECOLI (P22257) (432 aa), Fasta scores: E(): 8.1e-23, 25.4% identity in 433 aa overlap and Mycobacterium tuberculosis trigger factor Rv2462c SW:TIG_MYCTU (O53189) (466 aa), Fasta scores: E(): 0, 70.1% identity in 468 aa overlap.;UniProt_AC=Q9CBY2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1822935	1824611	.	-	0	Locus=ML1512c;Name=ML1512c;Function=;Product=conserved hypothetical protein;Comments=ML1512c, len: 558 aa. Conserved hypothetical protein. Highly similar to many proteins of undefined function including: Bacillus subtilis SW:YKQC_BACSU (Q45493) (555 aa), Fasta scores: E(): 0, 36.9% identity in 547 aa overlap and Mycobacterium tuberculosis Rv2752c TR:O33294 (EMBL:AL008967) (558 aa), Fasta scores: E(): 0, 89.1% identity in 558 aa overlap. Contains Pfam match to entry PF02147 UPF0036, Uncharacterized protein family UPF0036. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily.;UniProt_AC=Q9CBW5;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1794103	1794429	.	-	0	Locus=ML1489c;Name=fdxC;Function=;Product=PROBABLE FERREDOXIN FDXC;Comments=ML1489c, len: 108 aa. Probable fdxC, ferredoxin. Highly similar to many ferredoxins including: Mycobacterium smegmatis SW:FER_MYCSM (P00215) (106 aa), Fasta scores: E(): 0, 86.7% identity in 105 aa overlap and Mycobacterium tuberculosis Rv1177 TR:O50433 (EMBL:AL010186) (108 aa), Fasta scores: E(): 0, 90.6% identity in 106 aa overlap. Contains Pfam match to entry PF00037 fer4, 4Fe-4S binding domain. Contains PS00198 4Fe-4S ferredoxins. Note previously known as fdxA. ;UniProt_AC=Q9CBX7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1550234	1551388	.	+	0	Locus=ML1302;Name=mshC;Function=;Product=Probable cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC;Comments=ML1302, len: 384 aa. Probable mshC, cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase (see Rawat et al., 2002). Highly similar to multiple cysteinyl-tRNA synthetases including: Escherichia coli SW:SYC_ECOLI (P21888) (461 aa), Fasta scores: E(): 0, 36.8% identity in 386 aa overlap and to Mycobacterium tuberculosis Rv2130C SW:SYC2_MYCTU (O33264) mshC, cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase (414 aa), Fasta scores: E(): 0, 85.1% identity in 383 aa overlap. Contains Pfam match to entry PF01406 tRNA-synt_1e, tRNA synthetases class I (C). Note previously known as cysS2.;UniProt_AC=Q49784;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1788674	1791262	.	+	0	Locus=ML1486;Name=pepN;Function=;Product=PROBABLE AMINOPEPTIDASE N PEPN (LYSYL AMINOPEPTIDASE) (LYS-AP) (ALANINE AMINOPEPTIDASE);Comments=ML1486, len: 862 aa. Probable pepN, aminopeptidase (EC 3.4.11.2). Highly similar to many aminopeptidases including: Streptomyces lividans aminopeptidase N (EC 3.4.11.2) SW:AMPN_STRLI (Q11010) (857 aa), Fasta scores: E(): 0, 51.6% identity in 866 aa overlap and Mycobacterium tuberculosis aminopeptidase Rv2467 TR:O53194 (EMBL:AL021246) (861 aa), Fasta scores: E(): 0, 83.3% identity in 862 aa overlap. Contains Pfam match to entry PF01433 Peptidase_M1, Peptidase family M1. Contains PS00142 Neutral zinc metallopeptidases. BELONGS TO PEPTIDASE FAMILY M1 (ZINC METALLOPROTEASE), ALSO KNOWN AS THE PEPN SUBFAMILY. ;UniProt_AC=Q9CBX9;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1693617	1694816	.	+	0	Locus=ML1412;Name=argG;Function=;Product=Probable Argininosuccinate synthase ArgG (Citrulline--aspartate ligase);Comments=ML1412, len: 399 aa. Probable argG, Argininosuccinate synthase (EC 6.3.4.5). Highly similar to many argininosuccinate synthases involved in arginine biosynthesis, including: Streptomyces clavuligerus SW:ASSY_STRCL (P50986) (397 aa), Fasta scores: E(): 0, 67.0% identity in 397 aa overlap and Mycobacterium tuberculosis Rv1658 SW:ASSY_MYCTU (P94993) (398 aa), Fasta scores: E(): 0, 91.0% identity in 398 aa overlap. Contains Pfam match to entry PF00764 Arginosuc_synth, Arginosuccinate synthase. Contains PS00564 Argininosuccinate synthase signature 1. Contains PS00565 Argininosuccinate synthase signature 2. Belongs to the argininosuccinate synthase family. Subfamily 1;UniProt_AC=Q9CC10;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1905767	1906945	.	-	0	Locus=ML1581c;Name=gcpE;Function=;Product=PROBABLE GCPE PROTEIN;Comments=ML1581c, len: 392 aa. Probable gcpE protein. Highly similar to many GcpE orthologues the function of which is unknown. However in E. coli gcpE has been shown to be an essential gene. Similar to Escherichia coli SW:GCPE_ECOLI (P27433) (372 aa), Fasta scores: E(): 0, 45.5% identity in 330 aa overlap and Mycobacterium tuberculosis Rv2868c TR:O33350 (EMBL:AL008883) (387 aa), Fasta scores: E(): 0, 87.6% identity in 388 aa overlap.;UniProt_AC=Q9CBU5;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1779777	1781057	.	-	0	Locus=ML1477c;Name=clpX;Function=;Product=PROBABLE ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX;Comments=ML1477c, len: 426 aa. Probable clpX, ATP-dependent Clp protease ATP-binding subunit (EC 3.4.-.-). Highly similar to many ATP-dependent Clp protease ATP-binding subunits e.g. Bacillus subtilis SW:CLPX_BACSU (P50866) (420 aa), Fasta scores: E(): 0, 63.4% identity in 426 aa overlap and Mycobacterium tuberculosis Rv2457c SW:CLPX_MYCTU (O53184) (426 aa), Fasta scores: E(): 0, 96.0% identity in 426 aa overlap. Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA). Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CBY6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2670329	2671879	.	+	0	Locus=ML2247;Name=cpsA;Function=;Product=POSSIBLE CONSERVED PROTEIN CPSA;Comments=ML2247, len: 516 aa. Possible cpsA, conserved protein. Similar to Mycobacterium tuberculosis cpsa CPSA OR Rv3484 OR MTCY13E12.37 TR:O06347 (EMBL:Z95390) fasta scores: E(): 0, 74.9% identity in 518 aa, and to Streptococcus agalactiae cpsx protein CPSX TR:Q9S2Z3 (EMBL:Y17241) fasta scores: E(): 1.9e-09, 26.0% identity in 254 aa, and to Streptomyces coelicolor putative transcriptional regulator SC6G4.33 TR:O86796 (EMBL:AL031317) fasta scores: E(): 4.6e-09, 27.2% identity in 327 aa.;UniProt_AC=Q50160;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1797616	1800207	.	-	0	Locus=ML1492c;Name=fbiC;Function=;Product=PROBABLE F420 BIOSYNTHESIS PROTEIN FBIC;Comments=ML1492c, len: 863 aa. Probable fbiC, F420 biosynthesis protein. Highly similar to Mycobacterium tuberculosis TR:O50429 (EMBL:AL010186) Probable fbiC, F420 biosynthesis protein (856 aa), Fasta scores: E(): 0, 88.3% identity in 846 aa overlap. And similar to many proteins of undefined function including: Streptomyces coelicolor TR:CAB88436 (EMBL:AL353815) (867 aa), Fasta scores: E(): 0, 62.5% identity in 839 aa overlap and ;UniProt_AC=Q9CBX6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1584499	1587261	.	+	0	Locus=ML1333;Name=helY;Function=;Product=PROBABLE ATP-DEPENDENT DNA HELICASE HELY;Comments=ML1333, len: 920 aa. Probable helY, DNA helicase (EC 3.6.1.-). Highly similar to many proposed Prokaryotic and Eukaryotic helicases including: Mycobacterium tuberculosis Rv2092c SW:HELY_MYCTU (Q10701) (906 aa), Fasta scores: E(): 0, 82.5% identity in 922 aa overlap and Saccharomyces cerevisiae ATP-dependent RNA helicase Dob1 SW:MTR4_YEAST (P47047) (1073 aa), Fasta scores: E(): 0, 27.2% identity in 972 aa overlap. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9ZBD8;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1606117	1609125	.	+	0	Locus=ML1346;Name=ML1346;Function=;Product=possible long-chain acyl-CoA synthase;Comments=ML1346, len: 1002 aa. Possible long-chain acyl-CoA synthase. Similar to many Prokaryotic and Eukaryotic long-chain acyl-CoA synthetases including: Mus musculus SW:VLCS_MOUSE (O35488) (620 aa), Fasta scores: E(): 1.5e-20, 24.7% identity in 570 aa overlap and Chromatium vinosum poly-beta-hydroxybutyrate polymerase (EC 2.3.1.-) SW:PHBC_CHRvI (P45370) (355 aa), Fasta scores: E(): 4.7e-17, 28.2% identity in 348 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1683 TR:O33185 (EMBL:Z98268) (999 aa), Fasta scores: E(): 0, 85.6% identity in 1002 aa overlap. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00120 Lipases.;UniProt_AC=Q9CC34;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1628033	1628896	.	+	0	Locus=ML1367;Name=ML1367;Function=;Product=PUTATIVE INITIATION INHIBITOR PROTEIN;Comments=ML1367, len: 287 aa. Putative initiation inhibitor protein, a soj-related protein probably  involved in cell process, similar to several proteins involved in plasmid/chromosome partioning or regulation of sporulation e.g. Neisseria meningitidis ParA family protein TR:CAB83392 (EMBL:AL162752) (257 aa), Fasta scores: E(): 0, 42.1% identity in 252 aa overlap and Bacillus subtilis SW:SOJ_BACSU (P37522) (253 aa), Fasta scores: E(): 0, 46.2% identity in 247 aa overlap, respectively. Also highly similar to Mycobacterium tuberculosis Rv1708 TR:O33207 (EMBL:Z98268) (318 aa), Fasta scores: E(): 0, 89.5% identity in 286 aa overlap. Contains Pfam match to entry PF00991 ParA, ParA family ATPase. Contains Pfam match to entry PF00142 fer4_NifH, 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family.;UniProt_AC=Q9CC29;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1568248	1570077	.	+	0	Locus=ML1316;Name=mpa;Function=;Product=Probable mycobacterium proteasome ATPase Mpa;Comments=ML1316, len: 609 aa. Probable mpa, mycobacterium proteasome ATPase (see Darwin et al., 2003) Highly similar to Mycobacterium tuberculosis mpa, proteasome ATPase Rv2115c SW:YL15_MYCTU (O33250) (609 aa), Fasta scores: E(): 0, 92.8% identity in 609 aa overlap. And many AAA ATPase-family proteins including: Rhodococcus erythropolis ARC protein TR:O50202 (EMBL:AF088800) (591 aa), Fasta scores: E(): 0, 81.8% identity in 588 aa overlap, Methanococcus jannaschii cell division cycle protein SW:YB56_METJA (Q58556) (903 aa), Fasta scores: E(): 1.6e-17, 46.8% identity in 250 aa overlap. Contains possible coiled-coils between residues 76..98. Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00674 AAA-protein family signature.;UniProt_AC=P46509;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1734473	1736407	.	-	0	Locus=ML1441c;Name=ppm1b;Function=;Product=Polyprenol-monophosphomannose synthase Ppm1b;Comments=ML1441c, len: 644 aa. Probable ppm1b, Polyprenol-monophosphomannose synthase. Highly similar to the N-terminus of a Polyprenol-monophosphomannose synthase from Mycobacterium tuberculosis Rv2051c TR:O53493 (EMBL:AL021899) (874 aa), Fasta scores: E(): 0, 67.7% identity in 601 aa overlap. Homology to Rv2051c continues downstream of this ORF in a different frame suggesting a possible frameshift. Also similar to several apolipoprotein N-acyltransferases (EC 2.3.1.-) involved in lipoprotein biosynthesis e.g. Rhizobium meliloti SW:LNT_RHIME (Q52910) (541 aa), Fasta scores: E(): 1.3e-08, 26.0% identity in 515 aa overlap. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00795 CN_hydrolase, Carbon-nitrogen hydrolase.;UniProt_AC=O32928;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1598386	1599192	.	-	0	Locus=ML1340c;Name=ribD;Function=INVOLVED IN RIBOFLAVIN BIOSYNTHESIS (AT THE SECOND AND THIRD STEPS). CONVERTS 2,5-DIAMINO-6-(RIBOSYLAMINO)-4(3H)-PYRIMIDINONE 5'-PHOSPHATE INTO 5-AMINO-6-(RIBOSYLAMINO)-2,4(1H,3H)-PYRIMIDINEDIONE 5'-PHOSPHATE [CATALYTIC ACTIVITY 1: 2,5-DIAMINO-6-HYDROXY-4-(5-PHOSPHORIBOSYLAMINO)PYRIMIDINE + H(2)O = 5-AMINO-6-(5-PHOSPHORIBOSYLAMINO)URACIL + NH(3)] [CATALYTIC ACTIVITY 2: 5-AMINO-6-(5-PHOSPHORIBITYLAMINO)URACIL + NADP(+) = 5-AMINO-6-(5-PHOSPHORIBOSYLAMINO)URACIL + NADPH].;Product=POSSIBLE BIFUNCTIONAL ENZYME RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBD: DIAMINOHYDROXYPHOSPHORIBOSYLAMINOPYRIMIDINE DEAMINASE (RIBOFLAVIN-SPECIFIC DEAMINASE) + 5-AMINO-6-(5-PHOSPHORIBOSYLAMINO)URACIL REDUCTASE (HTP REDUCTASE);Comments=ML1340c, len: 268 aa. Possible ribD (alternate gene name: ribG), bifunctional riboflavin biosynthesis protein including diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) uracil reductase (EC 3.5.4.26 and 1.1.1.193). Similar to Mycobacterium tuberculosis Rv2671 TR:P71968 (EMBL:Z80225) bifunctional riboflavin biosynthesis protein (258 aa), Fasta scores: E(): 0, 72.9% identity in 251 aa overlap. And similar to the C-terminal reductase domains of several riboflavin biosynthetic proteins e.g. Escherichia coli RibD SW:RIBD_ECOLI (X64395) (367 aa), Fasta scores: E(): 0.0028, 23.8% identity in 227 aa overlap. Contains Pfam match to entry PF01872 RibD_C, RibD C-terminal domain.;UniProt_AC=O05684;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1975129	1975827	.	-	0	Locus=ML1638c;Name=ML1638c;Function=;Product=conserved hypothetical protein;Comments=ML1638c, len: 232 aa. Conserved hypothetical protein.  Highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis Rv2229c SW:YM29_MYCTU (Q10513) (245 aa), Fasta scores: E(): 0, 60.9% identity in 230 aa overlap. Contains a possible coiled-coil between residues 100..139.;UniProt_AC=Q9CBS9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1661669	1663765	.	+	0	Locus=ML1387;Name=uvrB;Function=INVOLVED IN NUCLEOTIDE EXCISION REPAIR. THE ABC EXCISION NUCLEASE IS A DNA REPAIR ENZYME THAT CATALYZES THE EXCISION REACTION OF UV-DAMAGED NUCLEOTIDE SEGMENTS PRODUCING OLIGOMERS HAVING THE MODIFIED BASE(S). UVRB STIMULATES THE ATPASE ACTIVITY OF UVRA IN THE PRESENCE OF UV-IRRADIATED DOUBLE-STRANDED DNA. IT ALSO ENHANCES THE ABILITY OF UVRA TO BIND TO UV-IRRADIATED DUPLEX DNA;Product=PROBABLE EXCINUCLEASE ABC (SUBUNIT B - HELICASE) UVRB;Comments=ML1387, len: 698 aa. Probable uvrB, excinuclease ABC subunit B. Highly similar to many excinucleases ABC (subunit B), involved in DNA repair following UV damage, including: Micrococcus luteus SW:UVRB_MICLU (P10125) (709 aa), Fasta scores: E(): 0, 71.4% identity in 700 aa overlap and Mycobacterium tuberculosis Rv1633 SW:UVRB_MYCTU (O06150) (698 aa), Fasta scores: E(): 0, 94.7% identity in 698 aa overlap. Contains Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase. Contains Pfam match to entry PF02151 UVR, UvrB/uvrC motif. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=P57991;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2761710	2762480	.	+	0	Locus=ML2331;Name=ML2331;Function=;Product=possible secreted protein;Comments=ML2331, len: 256 aa. Possible secreted protein. Similar to Mycobacterium tuberculosis hypothetical 24.8 kDa protein Rv3717 TR:O69684 (EMBL:AL022121) (241 aa) fasta scores: E(): 0, 82.0% identity in 244 aa, and to Streptomyces coelicolor putative secreted protein TR:CAB93433 (EMBL:AL357591) (336 aa) fasta scores: E(): 1.5e-24, 38.8% identity in 242 aa. Note contains a Pfam match to PF01520 N-acetylmuramoyl-L-alanine amidase. Contains Pfam match to entry PF01520 Amidase_3, N-acetylmuramoyl-L-alanine amidase. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CB75;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1880183	1882957	.	-	0	Locus=ML1556c;Name=infB;Function=IF-2, ONE OF THE ESSENTIAL COMPONENTS FOR THE INITIATION OF PROTEIN SYNTHESIS IN VITRO, PROTECTS FORMYLMETHIONYL-TRNA FROM SPONTANEOUS HYDROLYSIS AND PROMOTES ITS BINDING TO THE 30S RIBOSOMAL SUBUNITS. IT IS ALSO INVOLVED IN THE HYDROLYSIS OF GTP DURING THE FORMATION OF THE 70S RIBOSOMAL COMPLEX.;Product=PROBABLE TRANSLATION INITIATION FACTOR IF-2 INFB;Comments=ML1556c, len: 924 aa. Probable infB, initiation factor IF-2. Highly similar to Mycobacterium tuberculosis SW:IF2_MYCTU (P71613) (900 aa), Fasta scores: E(): 0, 83.6% identity in 933 aa overlap.  Similar in the C-terminus to many translation initiation factors e.g. Bacillus subtilis SW:IF2_BACSU (P17889) (716 aa), Fasta scores: E(): 0, 45.5% identity in 686 aa overlap. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family. Contains Pfam match to entry PF02131 IF2, Initiation factor 2. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9Z5I9;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1871005	1871967	.	-	0	Locus=ML1546c;Name=truB;Function=;Product=PROBABLE TRNA PSEUDOURIDINE SYNTHASE B TRUB (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE);Comments=ML1546c, len: 320 aa. Probable tRNA pseudouridine 55 synthase (EC 4.2.1.70). Highly similar to many tRNA pseudouridine synthases B including: Escherichia coli SW:TRUB_ECOLI (X13270) (314 aa), Fasta scores: E(): 1.7e-19, 36.4% identity in 316 aa overlap and Mycobacterium tuberculosis Rv2793c SW:TRUB_MYCTU (O33335) (298 aa), Fasta scores: E(): 0, 74.1% identity in 293 aa overlap. Contains Pfam match to entry PF01509 TruB_N, TruB family pseudouridylate synthase (N terminal domain).;UniProt_AC=Q9Z5I4;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1877248	1878690	.	+	0	Locus=ML1553;Name=proS;Function=;Product=Probable prolyl tRNA synthetase ProS;Comments=ML1553, len: 480 aa. Probable proS, prolyl-tRNA synthetase (EC 6.1.1.15). Highly similar to many prolyl tRNA synthetases including: SYP_CLOST|Q9L4Q8 from Clostridium sticklandii  (481 aa), Fasta scores: E(): 0, (46.5% identity in 477 aa overlap) and to parts of the Eukaryotic multifunctional aminoacyl-tRNA synthetases such as Homo sapiens (Human) SYEP_HUMAN|P07814 (1440 aa), Fasta scores: E(): 0, (44.5% identity in 467 aa overlap). Note codon 8 may offer an alternative translational start site. Contains Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II (G, H, P, S and T). Belongs to class-II aminoacyl-tRNA synthetase family.;UniProt_AC=Q9Z5I7;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1901941	1903767	.	-	0	Locus=ML1577c;Name=ML1577c;Function=;Product=POSSIBLE PENICILLIN-BINDING LIPOPROTEIN;Comments=ML1577c, len: 608 aa. Probable penicillin binding protein. Similar to many penicillin binding proteins e.g. Streptomyces clavuligerus high molecular weight group B penicillin binding protein TR:P72405 (EMBL:U56256) (551 aa), Fasta scores: E(): 6.3e-27, 29.9% identity in 609 aa overlap and Mycobacterium tuberculosis Rv2864c SW:O33346. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CBU6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2451096	2452046	.	+	0	Locus=ML2064;Name=blaR;Function=;Product=CONSERVED HYPOTHETICAL TRANSMEMBRANE PROTEIN;Comments=ML2064, len: 316 aa. Conserved hypothetical transmembrane protein.  Similar to Mycobacterium tuberculosis transmembrane protein Rv1845c TR:P95164 (EMBL:Z83859) fasta scores: E(): 0, 87.6% in 314 aa, and to Streptomyces coelicolor putative integral membrane protein SC10A7.04 TR:Q9XAS1 (EMBL:AL078618) fasta scores: E(): 1.8e-19, 32.6% in 328 aa.;UniProt_AC=O32910;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1886300	1887904	.	-	0	Locus=ML1562c;Name=efpA;Function=;Product=POSSIBLE INTEGRAL MEMBRANE EFFLUX PROTEIN EFPA;Comments=ML1562c, len: 534 aa. Possible efpA, integral membrane efflux protein. Highly similar to several transmembrane transport proteins including: Streptomyces lipmanii SW:PUR8_STRLP (P42670) (503 aa), Fasta scores: E(): 0, 33.3% identity in 481 aa overlap and Mycobacterium tuberculosis Rv2846c TR:O05813 (EMBL:Z95207) (530 aa), Fasta scores: E(): 0, 86.5% identity in 535 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter.;UniProt_AC=Q9Z5J5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1906998	1908212	.	-	0	Locus=ML1582c;Name=ML1582c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML1582c, len: 404 aa. Probable conserved transmembrane protein. Similar to many including several putative metalloproteases e.g. Treponema pallidum TR:O83609 (EMBL:AE001235) (450 aa), Fasta scores: E(): 1.6e-10, 27.5% identity in 265 aa overlap and several proteins of undefined function e.g. Mycobacterium tuberculosis Rv2869c TR:O33351 (EMBL:AL008883) (404 aa), Fasta scores: E(): 0, 82.2% identity in 404 aa overlap. Contains possible membrane spanning hydrophobic domains and a possible N-terminal signal sequence. Contains Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF).;UniProt_AC=Q9CBU4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1975873	1977030	.	-	0	Locus=ML1639c;Name=ML1639c;Function=;Product=conserved hypothetical protein;Comments=ML1639c, len: 385 aa. Conserved hypothetical protein. Highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis Rv2230c SW:YM30_MYCTU (Q10514) (379 aa), Fasta scores: E(): 0, 79.5% identity in 385 aa overlap. Contains Pfam match to entry PF01784 DUF34, Domain of unknown function.;UniProt_AC=O69481;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2066954	2068522	.	+	0	Locus=ML1714;Name=ML1714;Function=;Product=conserved hypothetical protein;Comments=ML1714, len: 522 aa. Conserved hypothetical protein. Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis hypothetical protein Rv3031 TR:O53278 (EMBL:AL021287) (526 aa), Fasta scores: E(): 0, 86.3% identity in 526 aa overlap and Pyrococcus abyssi TR:Q9V0M7 (EMBL:AJ248285) (602 aa), Fasta scores: E(): 2.7e-22, 30.0% identity in 556 aa overlap.;UniProt_AC=Q9CBR4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2347451	2347564	.	-	0	Locus=ML1961c;Name=rpmJ;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L36 RPMJ;Comments=ML1961c, len: 37 aa. Probable rpmJ, 50S ribosomal protein L36. Similar to M. tuberculosis 50S ribosomal protein L36 rpmJ Rv3461c SW:RL36_MYCTU (P45810) (37 aa), Fasta scores: E(): 1e-15, 86.5% identity in 37 aa overlap. Contains PS00828 Ribosomal protein L36 signature.;UniProt_AC=Q9X7A2;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2692771	2693568	.	+	0	Locus=ML2269;Name=bpoC;Function=;Product=POSSIBLE PEROXIDASE BPOC (NON-HAEM PEROXIDASE);Comments=ML2269, len: 265 aa. Possible bpoC, peroxidase (EC 1.11.1.-). Similar to Mycobacterium tuberculosis hypothetical protein Rv0554 or MTCY25D10.33 TR:O06420 (EMBL:Z95558) (262 aa) fasta scores: E(): 0, 83.5% identity in 261 aa. Shows weak similarity to various hydrolases e.g. Rhodococcus opacus 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase pcaL TR:O67982 (EMBL:AF003947) (400 aa) fasta scores: E(): 1.9e-11, 27.4% identity in 266 aa. Also similar to oxidoreductases which have an alpha/beta hydrolase fold e.g. Streptomyces aureofaciens non-haem bromoperoxidase bpoA2 SW:BPA2_STRAU (P29715) (277 aa) fasta scores: E(): 1.6e-13, 29.5% identity in 275 aa. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.;UniProt_AC=Q9CBB1;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2557045	2559306	.	+	0	Locus=ML2156;Name=ML2156;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML2156, len: 753 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis Rv0862c hypothetical 79.7 kda protein TR:O53874 (EMBL:AL022004) fasta scores: E(): 0, 77.6% in 753 aa, and to Streptomyces coelicolor hypothetical 90.4 kda protein TR:CAB93395 (EMBL:AL357524) fasta scores: E(): 3.9e-27, 34.6% in 856 aa. Contains a probable helix-turn-helix motif at aa 277-298 (Score 1075, SD +2.85);UniProt_AC=Q9CBE1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2469475	2469873	.	-	0	Locus=ML2077c;Name=gcvH;Function=;Product=PROBABLE GLYCINE CLEAVAGE SYSTEM H PROTEIN GCVH;Comments=ML2077c, len: 132 aa. Probable gcvH, glycine cleavage system H protein. Similar to Mycobacterium tuberculosis probable glycine cleavage system H protein SW:GCSH_MYCTU (Q50607) fasta scores: E(): 0, 78.4% in 134 aa, and to Escherichia coli glycine cleavage system H protein SW:GCSH_ECOLI (P23884) fasta scores: E(): 1.5e-22, 49.6% in 129 aa. Contains Pfam match to entry PF01597 GCV_H, Glycine cleavage H-protein. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.;UniProt_AC=O32920;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2586148	2586552	.	+	0	Locus=ML2174;Name=cdd;Function=;Product=PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE);Comments=ML2174, len: 134 aa. Probable cdd, cytidine deaminase (EC 3.5.4.5). Similar to Mycobacterium tuberculosis cytidine deaminase Rv3315c TR:O53367 (EMBL:AL021841) fasta scores: E(): 3e-28, 56.8% in 132 aa, and to Mus musculus cytidine deaminase SW:CDD_MOUSE (P56389) fasta scores: E(): 5.2e-12, 39.8% in 118 aa. Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region. Contains PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.;UniProt_AC=Q9CBD3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2009608	2010252	.	-	0	Locus=ML1666c;Name=ML1666c;Function=;Product=PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN;Comments=ML1666c, len: 214 aa. Probable conserved integral membrane protein. Similar to several proteins of undefined function including: Streptomyces coelicolor putative integral membrane protein  TR:CAB93387 (EMBL:AL357523) (240 aa), Fasta scores: E(): 3.6e-25, 36.1% identity in 191 aa overlap and Mycobacterium tuberculosis Rv2968c TR:P95126 (EMBL:Z83018) (210 aa), Fasta scores: E(): 0, 72.4% identity in 214 aa overlap. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=O69464;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2381503	2383101	.	+	0	Locus=ML1994;Name=fadD10;Function=;Product=POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE);Comments=ML1994, len: 532 aa. Possible fadD10, fatty-acid-CoA synthetase (EC 6.2.1.-). Similar to Mycobacterium tuberculosis putative fatty-acid-CoA synthases e.g. Rv0099 or MTCY251.18 TR:Q10878 (EMBL:Z74410) (540 aa) fasta scores: E(): 0, 74.6% identity in 531 aa. Previously sequenced as TR:Q50176 (EMBL:Z46257). Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature.;UniProt_AC=Q50176;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2311565	2312068	.	-	0	Locus=ML1926c;Name=ML1926c;Function=;Product=putative tuberculin related peptide (AT103);Comments=ML1926c, len: 167 aa. Putative tuberculin related peptide (AT103). Similar to M. tuberculosis tuberculin related peptide (AT103) Rv0431 TR:P96277 (EMBL:Z84724) (164 aa), Fasta scores: E(): 1.6e-32, 67.5% identity in 163 aa overlap and TR:O69619 (EMBL:D00815) (172 aa), Fasta scores: E(): 1.5e-32, 67.1% identity in 164 aa overlap.;UniProt_AC=Q9CBI5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2327636	2327899	.	+	0	Locus=ML1941;Name=xseB;Function=BIDIRECTIONALLY DEGRADES SINGLE-STRANDED DNA INTO LARGE ACID-INSOLUBLE  OLIGONUCLEOTIDES, WHICH ARE THEN DEGRADED FURTHER INTO SMALL ACID-SOLUBLE OLIGONUCLEOTIDES [CATALYTIC ACTIVITY: EXONUCLEOLYTIC CLEAVAGE IN EITHER 5'- TO 3'- OR 3'- TO 5'-DIRECTION TO YIELD 5'-PHOSPHOMONONUCLEOTIDES.];Product=PROBABLE EXODEOXYRIBONUCLEASE VII (SMALL SUBUNIT) XSEA (EXONUCLEASE VII SMALL SUBUNIT);Comments=ML1941, len: 87 aa. Probable xseB, exonuclease VII small subunit (EC 3.1.11.6). Similar to M. tuberculosis exonuclease VII small subunit xseB Rv1107c, and to many others e.g. Escherichia coli exodeoxyribonuclease large subunit SW:EX7S_ECOLI (P22938) (79 aa), Fasta scores: E(): 0.021, 41.8% identity in 55 aa overlap.;UniProt_AC=Q9X784;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2865946	2867340	.	-	0	Locus=ML2396c;Name=cbs;Function=;Product=Probable cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (Hemoprotein H-450);Comments=ML2396c, len: 464 aa. Probable cbs (previously cysM2), cystathionine beta-synthase (EC 4.2.1.22). Similar to Prokaryotic and Eukaryotic cystathionine beta-synthases including: Mycobacterium tuberculosis Rv1077 TR:O53425 (EMBL:AL021897) (464 aa) fasta scores: E(): 0, 90.1% id in 464 aa and Homo sapiens SW:CBS_HUMAN (550 aa) fasta scores: E(): 0, 39.5% identity in 479 aa. Also similar to ML0839 from M. leprae. Contains 2 Pfam matches to entry PF00571 CBS, CBS domain. Contains Pfam match to entry PF00291 S_T_dehydratase, Pyridoxal-phosphate dependent enzyme. BELONGS TO THE CYSTEINE SYNTHASE/CYSTATHIONINE BETA-SYNTHASE FAMILY. Previously known as cysM2.;UniProt_AC=Q9CB65;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1953455	1954747	.	-	0	Locus=ML1628c;Name=ftsY;Function=;Product=PROBABLE CELL DIVISION PROTEIN FTSY (SRP RECEPTOR) (SIGNAL RECOGNITION PARTICLE RECEPTOR);Comments=ML1628c, len: 430 aa. Probable ftsY, cell division protein. Highly similar to the C-terminal portion of many proposed SRP family cell division proteins: Escherichia coli FtsY SW:FTSY_ECOLI (P10121) (497 aa), Fasta scores: E(): 0, 40.5% identity in 338 aa overlap. Also highly similar over the entire range to Mycobacterium tuberculosis Rv2921c SW:FTSY_MYCTU (Q10969) (422 aa), Fasta scores: E(): 0, 81.4% identity in 429 aa overlap. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00448 SRP54, SRP54-type protein. Contains PS00300 SRP54-type proteins GTP-binding domain signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O33010;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2450663	2451091	.	+	0	Locus=ML2063;Name=blaI;Function=;Product=POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN;Comments=ML2063, len: 142 aa. Possible transcriptional regulatory protein. Similar to Mycobacterium tuberculosis transcriptional regulatory protein Rv1846c TR:P95163 (EMBL:AL008609) fasta scores: E(): 0, 95.1% in 123 aa, and weakly to Bacillus licheniformis penicillinase repressor SW:BLAI_BACLI (P06555; P12286) fasta scores: E(): 1.1, 21.7% in 129 aa.;UniProt_AC=O32909;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2683154	2684398	.	-	0	Locus=ML2260c;Name=pitA;Function=;Product=PROBABLE LOW-AFFINITY INORGANIC PHOSPHATE TRANSPORTER INTEGRAL MEMBRANE PROTEIN PITA;Comments=ML2260c, len: 414 aa. Probable pitA, low-affinity inorganic phosphate transporter integral membrane protein. Similar to Mycobacterium tuberculosis probable low-affinity inorganic phosphate transporter PIT OR PITA OR Rv0545c OR MTCY25D10.24C SW:PIT_MYCTU (O06411) fasta scores: E(): 0, 76.3% identity in 418 aa, and to Bacillus subtilis probable low-affinity inorganic phosphate transporter PIT SW:PIT_BACSU (O34436) fasta scores: E(): 0, 43.9% identity in 312 aa. Contains Pfam match to entry PF01384 PHO4, Phosphate transporter family. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q50173;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2129664	2131040	.	-	0	Locus=ML1755c;Name=sdaA;Function=;Product=PROBABLE L-SERINE DEHYDRATASE SDAA (L-SERINE DEAMINASE) (SDH) (L-SD);Comments=ML1755c, len: 458 aa. Probable sdaA, L-serine dehydratase (EC 4.2.1.13). Highly similar to many L-serine dehydratases including: Escherichia coli SW:TDCG_ECOLI (P42630) (454 aa), Fasta scores: E(): 0, 53.2% identity in 457 aa overlap and Mycobacterium tuberculosis Rv0069c SW:SDHL_MYCTU (O53614) (461 aa), Fasta scores: E(): 0, 69.2% identity in 461 aa overlap.;UniProt_AC=Q9CBP2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2037162	2038172	.	-	0	Locus=ML1691c;Name=leuB;Function=;Product=PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH);Comments=ML1691c, len: 336 aa. Probable leuB, 3-isopropylmalate dehydrogenase (EC 1.1.1.85). Highly similar to 3-isopropylmalate dehydrogenases, involved in leucine biosynthesis, from Mycobacterium bovis SW:LEU3_MYCBO (P94929) (336 aa), Fasta scores: E(): 0, 83.9% identity in 336 aa overlap and Mycobacterium tuberculosis Rv2995c SW:LEU3_MYCTU (P95313) (336 aa), Fasta scores: E(): 0, 83.9% identity in 336 aa overlap. Contains Pfam match to entry PF00180 isodh, Isocitrate and isopropylmalate dehydrogenases.;UniProt_AC=O33117;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2721471	2722016	.	+	0	Locus=ML2296;Name=ML2296;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2296, len: 181 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv3669 or MTV025.017 TR:O69637 (EMBL:AL022121) (172 aa) fasta scores: E(): 0, 77.9% identity in 181 aa. Similar to Streptomyces coelicolor putative integral membrane transport protein SCH5.28 TR:Q9X930 (EMBL:AL035636) (162 aa) fasta scores: E(): 3.3e-10, 37.3% identity in 153 aa, and to putative integral membrane protein SCI7.29C TR:Q9X9W1 (EMBL:AL096743) (165 aa) fasta scores: E(): 1.1e-05, 32.1% identity in 134 aa. Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CB97;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2027720	2028655	.	+	0	Locus=ML1682;Name=mutT1;Function=;Product=POSSIBLE HYDROLASE MUTT1;Comments=ML1682, len: 311 aa. Possible mutT1 hydrolase. Similar to Mycobacterium tuberculosis TR:P95110 (EMBL:Z83018) Rv2985 (317 aa), Fasta scores: E(): 0, 71.5% identity in 316 aa overlap and Streptomyces coelicolor putative MutT-like protein TR:CAB88476 (EMBL:AL353816) (142 aa), Fasta scores: E(): 2.6e-17, 47.7% identity in 128 aa overlap. Contains Pfam match to entry PF00293 mutT, Bacterial  mutT protein. Contains PS00893 mutT domain signature.;UniProt_AC=Q9CBR8;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2220763	2222079	.	-	0	Locus=ML1833c;Name=secY;Function=;Product=PROBABLE PREPROTEIN TRANSLOCASE SECY;Comments=ML1833c, len: 438 aa. Probable secY, preprotein translocase. Similar to M. tuberculosis preprotein translocase secy subunit Rv0732 SW:SECY_MYCTU (P94926) (441 aa), Fasta scores: E(): 0, 91.6% identity in 441 aa overlap, and to many others e.g. Bacillus subtilis SW:SECY_BACSU (P16336) (431 aa), Fasta scores: E(): 0, 42.7% identity in 445 aa overlap. Contains Pfam match to entry PF00344 secY, eubacterial secY protein. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00756 Protein secY signature 2.;UniProt_AC=O33006;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1923194	1924027	.	-	0	Locus=ML1598c;Name=rpsB;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S2 RPSB;Comments=ML1598c, len: 277 aa. Probable rpsB, 30S ribosomal protein S2. Highly similar to many 30s ribosomal proteins (S2) including: Bacillus subtilis SW:RS2_BACSU (P21464) (245 aa), Fasta scores: E(): 0, 57.6% identity in 250 aa overlap and Mycobacterium tuberculosis Rv2890c SW:RS2_MYCTU (Q10796) (287 aa), Fasta scores: E(): 0, 91.5% identity in 270 aa overlap. Contains Pfam match to entry PF00318 Ribosomal_S2, Ribosomal protein S2. Contains PS00962 Ribosomal protein S2 signature 1.;UniProt_AC=O33038;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1922362	1923192	.	-	0	Locus=ML1597c;Name=tsf;Function=;Product=PROBABLE ELONGATION FACTOR TSF (EF-TS);Comments=ML1597c, len: 276 aa. Probable tsf, elongation factor (EF-Ts). Highly similar to many elongation factors including: Streptomyces coelicolor SW:EFTS_STRCO (O31213) (278 aa), Fasta scores: E(): 0, 52.5% identity in 282 aa overlap and Mycobacterium tuberculosis Rv2889c SW:EFTS_MYCTU (Q10788) (271 aa), Fasta scores: E(): 0, 83.7% identity in 276 aa overlap. Contains Pfam match to entry PF02094 TS-N, TS-N domain. Contains Pfam match to entry PF00889 EF_TS, Elongation factor TS. Contains PS01127 Elongation factor Ts signature 2. Contains PS01126 Elongation factor Ts signature 1.;UniProt_AC=O33039;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1954861	1958472	.	-	0	Locus=ML1629c;Name=smc;Function=;Product=PROBABLE CHROMOSOME PARTITION PROTEIN SMC;Comments=ML1629c, len: 1203 aa. Probable smc, chromosome partition protein. Highly similar to many proteins involved in chromosome segregation and partition including: Bacillus subtilis Smc SW:SMC_BACSU (P51834) (1186 aa), Fasta scores: E(): 0, 31.5% identity in 1242 aa overlap and Mycobacterium tuberculosis Rv2922c SW:SMC_MYCTU (Q1097) (1205 aa), Fasta scores: E(): 0, 79.2% identity in 1208 aa overlap. Contains multiple possible coiled-coiled regions between residues 174..190, 260..279, 340..374, 397..433, 451..489, 725..754. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CBT5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2020081	2021058	.	-	0	Locus=ML1676c;Name=thiL;Function=;Product=PROBABLE THIAMINE-MONOPHOSPHATE KINASE THIL (THIAMINE-PHOSPHATE KINASE);Comments=ML1676c, len: 325 aa. Probable thiL, thiamine-monophosphate kinase (EC 2.7.4.16). Similar to several thiamine-monophosphate kinases including: Escherichia coli SW:THIL_ECOLI (P77785) (325 aa), Fasta scores: E(): 1.1e-18, 35.3% identity in 278 aa overlap and Mycobacterium tuberculosis Rv2977c TR:P95118 (P95118) (333 aa), Fasta scores: E(): 0, 80.9% identity in 314 aa overlap. Contains Pfam match to entry PF00586 AIRS, AIR synthase related protein.;UniProt_AC=Q9CBS2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1945512	1947482	.	+	0	Locus=ML1623;Name=htpG;Function=;Product=PROBABLE CHAPERONE PROTEIN  HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G);Comments=ML1623, len: 656 aa. Probable htpG, heat shock protein Hsp90 family.  Highly similar to many heat shock 90 family proteins, including: Escherichia coli SW:HTPG_ECOLI (P10413) (624 aa), Fasta scores: E(): 0, 45.4% identity in 656 aa overlap and Mycobacterium tuberculosis Rv2299c SW:HTPG_MYCTU (Q50667) (647 aa), Fasta scores: E(): 0, 80.8% identity in 656 aa overlap. Contains 2 Pfam matches to entry PF00183 HSP90, Hsp90 protein. Contains PS00298 Heat shock hsp90 proteins family signature.;UniProt_AC=O33012;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1964380	1965915	.	-	0	Locus=ML1632c;Name=ML1632c;Function=;Product=Probable exported protease;Comments=ML1632c, len: 511 aa. Probable exported protease. Highly similar to Mycobacterium tuberculosis Rv2223C SW:YM23_MYCTU (Q10508) (520 aa), Fasta scores: E(): 0, 75.8% identity in 520 aa overlap. And similar to Streptomyces lividans tripeptidylaminopeptidase precursor TR:Q54410 (EMBL:L27466) (537 aa), Fasta scores: E(): 0, 30.9% identity in 489 aa overlap. Also similar to ML1633 from M. leprae. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.;UniProt_AC=Q9CBT2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1999998	2000846	.	-	0	Locus=ML1658c;Name=fpg;Function=INVOLVED IN BASE EXCISION REPAIR (REPAIR OF OXIDIZED PURINES). THIS ENZYME MAY PLAY A SIGNIFICANT ROLE IN PROCESSES LEADING TO RECOVERY FROM MUTAGENESIS AND/OR CELL DEATH BY ALKYLATING AGENTS [CATALYTIC ACTIVITY HYDROLYSIS OF DNA CONTAINING RING-OPENED N7-METHYLGUANINE RESIDUES, RELEASING 2,6-DIAMINO-4-HYDROXY-5-(N-METHYL)FORMAMIDOPYRIMIDE].;Product=Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA GLYCOSYLASE);Comments=ML1658c, len: 282 aa. Probable formamidopyrimidine-DNA glycosylase (EC 3.2.2.23). Highly similar to many formamidopyrimidine-DNA glycosylases thought to be involved in DNA repair after exposure to alkylating agents e.g. Escherichia coli SW:FPG_ECOLI (P05523) (215 aa), BlastP Expect 8.7 and Mycobacterium tuberculosis SW:FPG_MYCTU (Q10959) (289 aa), Fasta scores: E(): 0, 80.6% identity in 289 aa overlap. Contains Pfam match to entry PF01149 Fapy_DNA_glyco, Formamidopyrimidine-DNA glycosylase.;UniProt_AC=O69470;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1994880	1996130	.	+	0	Locus=ML1655;Name=kasA;Function=INVOLVED IN FATTY ACID BIOSYNTHESIS (MYCOLIC ACIDS SYNTHESIS); INVOLVED IN MEROMYCOLATE EXTENSION. CATALYZES THE CONDENSATION REACTION OF FATTY ACID SYNTHESIS BY THE ADDITION TO AN ACYL ACCEPTOR OF TWO CARBONS FROM MALONYL-ACP [CATALYTIC ACTIVITY: ACYL-[ACYL-CARRIER PROTEIN] + MALONYL-[ACYL-CARRIER PROTEIN] = 3-OXOACYL-[ACYL-CARRIER PROTEIN] + [ACYL-CARRIER PROTEIN] + CO(2)].;Product=3-oxoacyl-[acyl-carrier-protein] synthase 1 KasA (BETA-KETOACYL-ACP SYNTHASE) (KAS I) ;Comments=ML1655, len: 416 aa. Probable kasA, 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41). Highly similar to many 3-oxoacyl-[acyl-carrier-protein] synthases II involved in fatty acid biosynthesis including: Escherichia coli SW:FABF_ECOLI (P39435) (412 aa), Fasta scores: E(): 0, 41.1% identity in 411 aa overlap and Mycobacterium tuberculosis Rv2245 SW:FAB1_MYCTU (Q10524) (416 aa), Fasta scores: E(): 0, 92.5% identity in 416 aa overlap. Also highly similar to the adjoining CDS ML1655. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase.;UniProt_AC=Q9CBS7;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2025422	2027641	.	+	0	Locus=ML1681;Name=ppk;Function=;Product=PROBABLE POLYPHOSPHATE KINASE PPK (POLYPHOSPHORIC ACID KINASE) (ATP-POLYPHOSPHATE PHOSPHOTRANSFERASE);Comments=ML1681, len: 739 aa. Probable ppk, polyphosphate kinase (EC 2.7.4.1). Highly similar to many polyphosphate kinases including: Escherichia coli SW:PPK_ECOLI (P28688) (687 aa), Fasta scores: E(): 0, 34.4% identity in 655 aa overlap and Mycobacterium tuberculosis Rv2984 TR:P95111 (EMBL:Z83018) (742 aa), Fasta scores: E(): 0, 87.9% identity in 742 aa overlap.;UniProt_AC=O33127;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2054614	2054913	.	-	0	Locus=ML1703c;Name=gatC;Function=COMPONENT OF THE TRANSLATIONAL APPARATUS. FURNISHES A MEANS FOR FORMATION OF CORRECTLY CHARGED GLN-TRNA(GLN) THROUGH THE TRANSAMIDATION OF MISACYLATED GLU- TRNA(GLN) IN ORGANISMS WHICH LACK GLUTAMINYL-TRNA SYNTHETASE. THE REACTION TAKES PLACE IN THE PRESENCE OF GLUTAMINE AND ATP THROUGH AN ACTIVATED GAMMA-PHOSPHO-GLU-TRNA(GLN) [CATALYTIC ACTIVITY: ATP + L-GLUTAMYL-TRNA(GLN) + L-GLUTAMINE = ADP + PHOSPHATE + L-GLUTAMINYL-TRNA(GLN) + L-GLUTAMATE].;Product=PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT C) GATC (Glu-ADT SUBUNIT C);Comments=ML1703c, len: 99 aa. Probable gatC, glutamyl-tRNA(Gln) amidotransferase, subunit C (EC 6.3.5.-). Highly similar to many glutamyl-tRNA(Gln) amidotransferases (subunit C) including: Bacillus subtilis SW:GATC_BACSU (O06492) (96 aa), Fasta scores: E(): 6.9e-08, 37.9% identity in 95 aa overlap and Mycobacterium tuberculosis Rv3012c SW:GATC_MYCTU (O53259) (99 aa), Fasta scores: E(): 3.1e-28, 74.7% identity in 99 aa overlap.;UniProt_AC=O33104;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2060896	2062128	.	-	0	Locus=ML1708c;Name=iscS;Function=;Product=PROBABLE CYSTEINE DESULFURASE ISCS (NIFS PROTEIN HOMOLOG) (NITROGENASE METALLOCLUSTERS BIOSYNTHESIS PROTEIN NIFS);Comments=ML1708c, len: 410 aa.  Probable iscS (alternate gene name: nifS), cysteine desulfurase (NifS-like protein) (EC 4.4.1.-). Highly similar to Mycobacterium tuberculosis NifS-like protein Rv3025c TR:O53272 (EMBL:AL021287) (393 aa), Fasta scores: E(): 0, 84.9% identity in 391 aa overlap and many aminotransferases resembling NifS e.g. Azotobacter vinelandii SW:NIFS_AZOVI (P05341) (402 aa), Fasta scores: E(): 0, 39.1% identity in 394 aa overlap. Also similar to ML0596 from M. leprae. Contains Pfam match to entry PF00266 aminotran_5, Aminotransferases class-V.;UniProt_AC=Q9CBR5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2068548	2069864	.	+	0	Locus=ML1715;Name=ML1715;Function=;Product=POSSIBLE TRANSFERASE;Comments=ML1715, len: 438 aa. Possible transferase. Highly similar to several proteins of undefined function including: Mycobacterium tuberculosis hypothetical protein Rv3032 TR:O53279 (EMBL:AL021287) (414 aa), Fasta scores: E(): 0, 87.9% identity in 414 aa overlap. Also similar to a putative transferase from Streptomyces coelicolor TR:Q9Z5B7 (EMBL:AL035478) (406 aa), Fasta scores: E(): 2.8e-22, 30.1% identity in 415 aa overlap. Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1.;UniProt_AC=Q9CBR3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2242938	2243594	.	-	0	Locus=ML1863c;Name=rplC;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L3 RPLC;Comments=ML1863c, len: 218 aa. Probable rplC, 50S ribosomal protein L3. Similar to M. tuberculosis 50S ribosomal protein L3 Rv0701 SW:RL3_MYCTU (P95049) (217 aa), Fasta scores: E(): 0, 93.5% identity in 217 aa overlap. Contains Pfam match to entry PF00297 Ribosomal_L3, Ribosomal protein L3. Contains PS00474 Ribosomal protein L3 signature.;UniProt_AC=P30762;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2083355	2084590	.	-	0	Locus=ML1727c;Name=serB2;Function=;Product=PROBABLE PHOSPHOSERINE PHOSPHATASE SERB2 (PSP) (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSPASE);Comments=ML1727c, len: 411 aa. Probable serB2, Phosphoserine phosphatase (EC 3.1.3.3). Similar in the C-terminus to many phosphoserine phosphatases including: Escherichia coli SW:SERB_ECOLI (P06862) (322 aa), Fasta scores: E(): 1.7e-29, 38.5% identity in 309 aa overlap and Mycobacterium tuberculosis Rv3042c TR:O53289 (EMBL:AL021287) (409 aa), Fasta scores: E(): 0, 86.3% identity in 408 aa overlap. Contains Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase.;UniProt_AC=Q9CBQ6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2090620	2091597	.	-	0	Locus=ML1731c;Name=nrdF;Function=INVOLVED IN THE DNA REPLICATION PATHWAY. CATALYZES THE BIOSYNTHESIS OF DEOXYRIBONUCLEOTIDES FROM THE CORRESPONDING RIBONUCLEOTIDES, PRECURSORS THAT ARE NECESSARY FOR DNA SYNTHESIS [CATALYTIC ACTIVITY: 2'-DEOXYRIBONUCLEOSIDE DIPHOSPHATE + OXIDIZED THIOREDOXIN + H(2)O = RIBONUCLEOSIDE DIPHOSPHATE + REDUCED THIOREDOXIN].;Product=RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R2F PROTEIN);Comments=ML1731c, len: 325 aa. Probable nrdF, ribonucleoside-diphosphate reductase, beta chain (EC 1.17.4.1). Highly similar to many ribonucleoside-diphosphate reductase 2 beta chains, involved in DNA replication, including: Escherichia coli SW:RIR4_ECOLI (P37146) (319 aa), Fasta scores: E(): 0, 71.6% identity in 320 aa overlap and Mycobacterium tuberculosis Rv3048c TR:Q50549 (EMBL:AL021287) (324 aa), Fasta scores: E(): 0, 93.5% identity in 324 aa overlap. Contains Pfam match to entry PF00268 ribonuc_red, Ribonucleotide reductases. Contains PS00368 Ribonucleotide reductase small subunit signature.;UniProt_AC=Q9CBQ2;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2123775	2127095	.	-	0	Locus=ML1753c;Name=ML1753c;Function=;Product=PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN;Comments=ML1753c, len: 1106 aa. Probable transcriptional regulatory protein. Highly similar to many from Mycobacterium tuberculosis e.g. probable transcriptional regulatory protein Rv1358 TR:Q11028 (EMBL:Z75555) (1159 aa), Fasta scores: E(): 0, 58.1% identity in 1084 aa overlap. Contains a putative helix-turn-helix motif situated between residues 1063..1084 (+2.87 SD). Contains a probable helix-turn-helix motif at aa 1063-1084 (Score 1080, SD +2.87) Contains Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00622 Bacterial regulatory proteins.;UniProt_AC=Q9CBP3;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2117017	2119182	.	-	0	Locus=ML1751c;Name=moeY;Function=;Product=POSSIBLE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEY;Comments=ML1751c, len: 721 aa. Possible moeY, Molybdopterin biosynthesis protein. Similar to Mycobacterium tuberculosis SW:YD55_MYCTU (Q11025) (715 aa), Fasta scores: E(): 0, 57.3% identity in 705 aa overlap. Contains Pfam match to entry PF00899 ThiF_family, ThiF family.;UniProt_AC=Q9CBP5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2143283	2144269	.	+	0	Locus=ML1768;Name=uspA;Function=;Product=PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPA;Comments=ML1768, len: 328 aa. Probable sugar transport integral membrane protein. Similar to M. tuberculosis Rv2316 TR:P71896 (EMBL:Z79702) (290 aa), Fasta scores: E(): 0, 82.4% identity in 289 aa overlap probable sugar transport protein uspA, and to many others e.g. Thermococcus litoralis maltore transporter malF TR:O51924 (EMBL:AF012836) (300 aa), Fasta scores: E(): 4.7e-28, 33.6% identity in 283 aa overlap. Also similar to ML1426, ML1087, ML1425 and ML1088 from M. leprae. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component.;UniProt_AC=Q9CBN8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2145172	2146512	.	+	0	Locus=ML1770;Name=uspC;Function=;Product=PROBABLE PERIPLASMIC SUGAR-BINDING LIPOPROTEIN USPC;Comments=ML1770, len: 446 aa. Probable uspC, sugar-binding lipoprotein component of sugar transport system. Similar to M. tuberculosis Rv2318 TR:P71894 (EMBL:Z79702) (440 aa), Fasta scores: E(): 0, 74.7% identity in 446 aa overlap probable sugar transport periplasmic binding protein uspC and to many others e.g. Alicyclobacillus acidocaldarius maltose binding protein precursor TR:Q9RHZ6 (EMBL:AJ252161) (427 aa), Fasta scores: E(): 3.8e-05, 22.2% identity in 347 aa overlap. Also similar to ML1427 from M. leprae. Contains probable signal sequence. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein.;UniProt_AC=Q9CBN6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2183202	2184326	.	-	0	Locus=ML1802c;Name=ML1802c;Function=;Product=POSSIBLE EXPORTED CONSERVED PROTEIN;Comments=ML1802c, len: 374 aa. Possible exported conserved protein. Similar to M. tuberculosis Rv1488 SW:YE88_MYCTU (P71768) (381 aa), Fasta scores: E(): 0, 89.8% identity in 373 aa overlap, and to many others members of the BAND 7 / MEC-2 family e.g. Streptomyces coelicolor conserved hypothetical protein SCI5.04C TR:Q9X9Z6 (EMBL:AL079332) (319 aa), Fasta scores: E(): 0, 54.7% identity in 311 aa overlap. Contains Pfam match to entry PF01145 Band_7, SPFH domain / Band 7 family. Contains PS00024 Hemopexin domain signature. Contains PS01270 Band 7 protein family signature.;UniProt_AC=Q9CBM5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2322206	2323276	.	-	0	Locus=ML1936c;Name=ML1936c;Function=;Product=Probable GTP binding protein;Comments=ML1936c, len: 356 aa. Probable GTP binding protein. Similar to M. tuberculosis probable GTP binding protein Rv1112 TR:O53459 (EMBL:AL021897) (357 aa), Fasta scores: E(): 0, 85.9% identity in 354 aa overlap, and to many others e.g. Haemophilus influenzae probable GTP-binding protein SW:YCHF_HAEIN (P44681) (362 aa), Fasta scores: E(): 0, 53.8% identity in 355 aa overlap. Also similar to ML1465 from M. leprae. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9X779;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2180192	2182102	.	-	0	Locus=ML1800c;Name=mutA;Function=;Product=PROBABLE METHYLMALONYL-CoA MUTASE SMALL SUBUNIT MUTA (MCM);Comments=ML1800c, len: 636 aa. Probable mutA, methylmalonyl-CoA mutase small subunit. Similar to M. tuberculosis mutA Rv1492 SW:MUTA_MYCTU (P71773) (615 aa), Fasta scores: E(): 0, 75.3% identity in 636 aa overlap, and many other methylmalonyl-CoA mutase beta-subunit e.g. Streptomyces cinnamonensis SW:SW:MUTA_STRCM (Q05064) (616 aa), Fasta scores: E(): 0, 42.7% identity in 626 aa overlap. Also similar to ML1799 from M. leprae. Contains Pfam match to entry PF01642 MM_CoA_mutase, Methylmalonyl-CoA mutase. Contains PS00544 Methylmalonyl-CoA mutase signature.;UniProt_AC=Q9CBM6;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2186802	2187611	.	-	0	Locus=ML1806c;Name=inhA;Function=THIS ISOZYME IS INVOLVED IN MYCOLIC ACID BIOSYNTHESIS. SECOND REDUCTIVE STEP IN FATTY ACID BIOSYNTHESIS. INVOLVED IN THE RESISTANCE AGAINST THE ANTITUBERCULOSIS DRUGS ISONIAZID AND ETHIONAMIDE [CATALYTIC ACTIVITY: ACYL-[ACYL-CARRIER PROTEIN] + NAD(+) = TRANS-2,3-DEHYDROACYL-[ACYL-CARRIER PROTEIN] + NADH].;Product=NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE);Comments=ML1806c, len: 269 aa. Probable inhA, NADH-dependent enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.9). Similar to M. tuberculosis inhA Rv1484 SW:INHA_MYCTU (P46533) (269 aa), Fasta scores: E(): 0, 90.3% identity in 269 aa overlap, and to many others e.g. Escherichia coli enoyl-[acyl-carrier-protein] reductase [NADH] SW:FABI_ECOLI (P29132) (261 aa), Fasta scores: E(): 1.2e-17, 33.2% identity in 268 aa overlap. Also similar to ML1807 from M. leprae.;UniProt_AC=Q9CBM1;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2212455	2214173	.	-	0	Locus=ML1828c;Name=PPE;Function=;Product=PPE-family protein;Comments=ML1828c, len: 572 aa. Member of the PPE protein family. Similar to Mycobacterium tuberculosis PPE-family proteins e.g. Rv0256c or MTV034.22C TR:O53678 (EMBL:AL021929) (556 aa) fasta scores: E(): 0, 63.5% identity in 564 aa. Previously sequenced as TR:O33009 (EMBL:Z98756). Contains Pfam match to entry PF00823 PPE, PPE family.;UniProt_AC=O33009;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	2226943	2228751	.	-	0	Locus=ML1839c;Name=sppA;Function=;Product=POSSIBLE PROTEASE IV SPPA (ENDOPEPTIDASE IV) (SIGNAL PEPTIDE PEPTIDASE);Comments=ML1839c, len: 602 aa. Possible protease IV, signal peptide peptidase (EC 3.4.21.-). Similar to M. tuberculosis protease IV, signal peptide peptidase Rv0724, TR:P95072 (EMBL:Z84395) (623 aa), Fasta scores: E(): 0, 80.2% identity in 602 aa overlap, and to many others e.g. Escherichia coli protease IV SW:SPPA_ECOLI (P08395) (618 aa), Fasta scores: E(): 2.3e-24, 33.1% identity in 531 aa overlap. Contains 2 Pfam matches to entry PF01343 Peptidase_U7, Peptidase family U7.;UniProt_AC=O33003;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2231264	2231662	.	-	0	Locus=ML1845c;Name=rpsH;Function=;Product=PROBABLE 30S RIBOSOMAL PROTEIN S8 RPSH;Comments=ML1845c, len: 132 aa. Probable rpsH, 30S ribosomal protein S8. Similar to M. tuberculosis 30S ribosomal protein S8 Rv0718 SW:RS8_MYCTU (P95066) (132 aa), Fasta scores: E(): 0, 93.9% identity in 132 aa overlap. Contains Pfam match to entry PF00410 Ribosomal_S8, Ribosomal protein S8. Contains PS00053 Ribosomal protein S8 signature.;UniProt_AC=O32997;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2240243	2240770	.	-	0	Locus=ML1858c;Name=rplV;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L22 RPLV;Comments=ML1858c, len: 175 aa. Probable rplV, 50S ribosomal protein L22. Similar to M. tuberculosis 50S ribosomal protein L22 Rv0706 SW:RL22_MYCTU (P95054) (197 aa), Fasta scores: E(): 0, 76.3% identity in 190 aa overlap. Contains Pfam match to entry PF00237 Ribosomal_L22, Ribosomal protein L22p/L17e. Contains PS00464 Ribosomal protein L22 signature.;UniProt_AC=O32986;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2257096	2259201	.	-	0	Locus=ML1878c;Name=fusA1;Function=;Product=PROBABLE ELONGATION FACTOR G FUSA1 (EF-G);Comments=ML1878c, len: 701 aa. Probable fusA1, elongation factor G. Similar to M. tuberculosis elongation factor G Rv0684 SW:EFG_MYCTU (O53790) (701 aa), Fasta scores: E(): 0, 90.3% identity in 701 aa overlap, and to many others e.g. Escherichia coli SW:EFG_ECOLI (P02996) (703 aa), Fasta scores: E(): 0, 59.2% identity in 703 aa overlap. Also similar to ML1498, ML0611, ML1877 and ML1556 from M. leprae. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family. Contains Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus. Contains PS00301 GTP-binding elongation factors signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=P30767;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2280870	2281403	.	-	0	Locus=ML1896c;Name=rplJ;Function=;Product=PROBABLE 50S RIBOSOMAL PROTEIN L10 RPLJ;Comments=ML1896c, len: 177 aa. Probable rplJ, 50S ribosomal protein L10. Similar to M. tuberculosis 50S ribosomal protein L10 rplJ OR Rv0651 SW:RL10_MYCTU (P96940) (178 aa), Fasta scores: E(): 0, 89.3% identity in 178 aa overlap. Contains Pfam match to entry PF00466 Ribosomal_L10, Ribosomal protein L10.;UniProt_AC=Q9CBK7;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2273276	2276812	.	-	0	Locus=ML1891c;Name=rpoB;Function=;Product=DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT);Comments=ML1891c, len: 1178 aa. Probable rpoB, DNA-directed RNA polymerase, beta chain (EC 2.7.7.6). Similar to M. tuberculosis DNA-directed RNA polymerase beta chain Rv0667 SW:RPOB_MYCTU (P47766) (1178 aa), Fasta scores: E(): 0, 94.9% identity in 1178 aa overlap, and to many others e.g. Synechocystis sp. SW:RPOB_SYNY3 (P77965) (1102 aa), Fasta scores: E(): 0, 55.0% identity in 1129 aa overlap. Contains Pfam match to entry PF00562 RNA_pol_B, RNA polymerase beta subunit. Contains PS01166 RNA polymerases beta chain signature.;UniProt_AC=P30760;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2287638	2288534	.	+	0	Locus=ML1903;Name=mmaA4;Function=INVOLVED IN MYCOLIC ACIDS MODIFICATION. CATALYZES UNUSUAL S-ADENOSYL-METHIONINE-DEPENDENT TRANSFORMATION OF A CIS-OLEFIN MYCOLIC ACID INTO A SECONDARY ALCOHOL. CATALYZES INTRODUCTION OF A HYDROXYL GROUP AT THE DISTAL POSITION ON MYCOLIC ACID CHAINS TO PRODUCE THE HYDROXYL MYCOLATE. Mycolic acids represent a major constituent of the mycobacterial cell wall complex. Methyl transfer results in formation of a secondary hydroxy group with an adjacent methyl branch; Olefinic mycolic acid methyl transferase.;Product=METHOXY MYCOLIC ACID SYNTHASE 4 MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE);Comments=ML1903, len: 298 aa. Probable mmaA4, methyl mycolic acid synthase (EC 2.1.1.-). Similar to M. tuberculosis methyl mycolic acid synthase 4 Rv0642c TR:P72028 (EMBL:U66108) (301 aa), Fasta scores: E(): 0, 87.5% identity in 296 aa overlap, and to many others e.g. M. tuberculosis cyclopropane-fatty-acyl-phospholipid synthase 1 SW:CFA1_MYCTU (Q11195) (287 aa), Fasta scores: E(): 0, 57.0% identity in 286 aa overlap. Also similar to ML2459, ML2426 and ML2334 from M. leprae.;UniProt_AC=Q9CBK3;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2294070	2294549	.	-	0	Locus=ML1910c;Name=ML1910c;Function=;Product=conserved hypothetical protein;Comments=ML1910c, len: 159 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical proteins e.g. Rv0635 or MTCY20H10.16 TR:P96926 (EMBL:Z92772) (158 aa) fasta scores: E(): 0, 84.9% identity in 159 aa. Also similar to Streptomyces coelicolor hypothetical protein SCD82.07 TR:CAB77410 (EMBL:AL160431) (150 aa) fasta scores: E(): 1.9e-11, 30.4% identity in 148 aa.;UniProt_AC=Q9CBJ6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2569168	2571312	.	-	0	Locus=ML2161c;Name=fadB;Function=;Product=PROBABLE FATTY OXIDATION PROTEIN FADB;Comments=ML2161c, len: 714 aa. Probable fadB, fatty oxidation protein. Similar to Mycobacterium tuberculosis fadB, fatty oxidationprotein Rv0860 TR:O53872 (EMBL:AL022004) fasta scores: E(): 0, 88.6% in 719 aa, and to Escherichia coli fatty oxidation complex alpha subunit SW:FADB_ECOLI (P21177) fasta scores: E(): 0, 33.0% in 684 aa. Also similar to ML1724, ML2402, ML2401, ML1241 and ML2118 from M. leprae. Contains Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.;UniProt_AC=Q9CBD8;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2302772	2303413	.	-	0	Locus=ML1919c;Name=ML1919c;Function=;Product=CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE);Comments=ML1919c, len: 213 aa. Probable carbonic anhydrase (EC 4.2.1.1). Similar to M. tuberculosis putative carbonic anhydrase Rv3588c TR:O53573 (EMBL:AL022075) (207 aa), Fasta scores: E(): 0, 84.5% identity in 207 aa overlap, and to others e.g. Chlamydomonas reinhardtii carbonic anhydrase precursor TR:Q39589 (EMBL:U41189) (267 aa), Fasta scores: E(): 7.9e-19, 34.4% identity in 192 aa overlap. Contains Pfam match to entry PF00484 Pro_CA, Prokaryotic-type carbonic anhydrases. Contains PS00704 Prokaryotic-type carbonic anhydrases signature 1. Contains PS00705 Prokaryotic-type carbonic anhydrases signature 2.;UniProt_AC=Q9CBJ1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2310778	2311500	.	-	0	Locus=ML1925c;Name=sodC;Function=;Product=PROBABLE PERIPLASMIC SUPEROXIDE DISMUTASE [CU-ZN] SODC;Comments=ML1925c, len: 240 aa. Probable periplasmic superoxide dismutase precursor (EC 1.15.1.1). Similar to M. tuberculosis superoxide dismutase precursor (Cu-Zn) Rv0432 TR:P96278 (EMBL:Z84724) (240 aa), Fasta scores: E(): 0, 72.0% identity in 239 aa overlap, and weakly similar to many others e.g. Photobacterium leiognathi superoxide dismutase SW:SODC_PHOLE (P00446) (173 aa), Fasta scores: E(): 0.0018, 29.6% identity in 189 aa overlap. Contains Pfam match to entry PF00080 sodcu, Copper/zinc superoxide dismutase (SODC). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CBI6;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2327950	2329080	.	+	0	Locus=ML1942;Name=ML1942;Function=;Product=PROBABLE CHOLESTEROL DEHYDROGENASE;Comments=ML1942, len: 376 aa. Probable cholesterol dehydrogenase (EC 1.1.1.-). Similar to M. tuberculosis cholesterol dehydrogenase Rv1106c TR:O53454 (EMBL:AL021897) (370 aa), Fasta scores: E(): 0, 75.5% identity in 375 aa overlap, and to Nocardia sp NAD(P)-dependent cholesterol dehydrogenase TR:Q03704 (EMBL:D90244) (364 aa), Fasta scores: E(): 0, 71.0% identity in 366 aa overlap. Also similar to ML0204 and ML1964 from M. leprae. Contains Pfam match to entry PF01073 3Beta_HSD, 3-beta hydroxysteroid dehydrogenase/isomerase family.;UniProt_AC=Q9X785;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2337626	2338927	.	-	0	Locus=ML1951c;Name=phoH2;Function=;Product=PROBABLE PHOH-LIKE PROTEIN PHOH2 (PHOSPHATE STARVATION-INDUCIBLE PROTEIN PSIH);Comments=ML1951c, len: 433 aa. Probable phoH2, PhoH-like protein. Similar to M. tuberculosis PhoH-like protein phoH2 Rv1095 TR:O53443 (EMBL:AL021897) (433 aa), Fasta scores: E(): 0, 92.8% identity in 432 aa overlap, and to others e.g. Escherichia coli PhoH-like protein YBEZ SW:PHOL_ECOLI (P77349) (359 aa), Fasta scores: E(): 1.1e-16, 31.2% identity in 276 aa overlap. Also similar to ML0627 from M. leprae. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9X792;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1965990	1967597	.	-	0	Locus=ML1633c;Name=ML1633c;Function=;Product=Probable exported protease;Comments=ML1633c, len: 535 aa. Probable exported protease (EC 3.4.-.-). Highly similar to Q10509|YM24_MYCTU Hypothetical protein Rv2224c from M. tuberculosis (520 aa), fasta scores: E(): 8.6e-188, (84.808% identity in 520 aa overlap) and  Mycobacterium tuberculosis Rv2223c SW:YM23_MYCTU (Q10508) (520 aa), Fasta scores: E(): 0, 50.1% identity in 511 aa overlap. Also similar to Streptomyces lividans tripeptidylaminopeptidase precursor TR:Q54410 (EMBL:L27466) (537 aa), Fasta scores: E(): 4.3e-23, 30.7% identity in 508 aa overlap.  Note this CDS is also highly similar to the adjoining CDS ML1632. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.;UniProt_AC=Q9CBT1;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2344713	2345756	.	-	0	Locus=ML1957c;Name=rpoA;Function=DNA-DEPENDENT RNA POLYMERASE CATALYZES THE TRANSCRIPTION OF DNA INTO RNA USING THE FOUR RIBONUCLEOSIDE TRIPHOSPHATES AS SUBSTRATES. THE AMINO-TERMINAL PORTION IS INVOLVED IN THE ASSEMBLY OF CORE RNAP, WHEREAS THE C-TERMINAL IS INVOLVED IN INTERACTION WITH TRANSCRIPTIONAL REGULATORS [CATALYTIC ACTIVITY: N NUCLEOSIDE TRIPHOSPHATE = N PYROPHOSPHATE + RNA(N)].;Product=PROBABLE DNA-DIRECTED RNA POLYMERASE (ALPHA CHAIN) RPOA (TRANSCRIPTASE ALPHA CHAIN) (RNA POLYMERASE ALPHA SUBUNIT) (DNA-DIRECTED RNA NUCLEOTIDYLTRANSFERASE);Comments=ML1957c, len: 347 aa. Probable rpoA, DNA-directed RNA polymerase (alpha chain) (EC 2.7.7.6). Similar to M. tuberculosis [alpha] subunit of RNA polymerase rpoA Rv3457c SW:RPOA_MYCTU (O06324) (347 aa), Fasta scores: E(): 0, 95.7% identity in 347 aa overlap. Contains Pfam match to entry PF01000 RNA_pol_A_bac, Bacterial RNA polymerase, alpha chain. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9X798;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2349343	2349951	.	+	0	Locus=ML1965;Name=rmlC;Function=INVOLVED IN dTDP-L-RHAMNOSE BIOSYNTHESIS, WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS: CONVERSION OF dTDP-4-KETO-6-DEOXY-D-GLUCOSE TO DTDP-4-KETO-RHAMNOSE [CATALYTIC ACTIVITY: dTDP-4-DEHYDRO-6-DEOXY-D-GLUCOSE = dTDP-4-DEHYDRO-6-DEOXY-L-MANNOSE].;Product=dTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC (dTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (dTDP-L-RHAMNOSE SYNTHETASE) (THYMIDINE DIPHOSPHO-4-KETO-RHAMNOSE 3,5-EPIMERASE);Comments=ML1965, len: 202 aa. Probable rmlC, dTDP-4-dehydrorhamnose 3,5-epimerase. Similar to M. tuberculosis dTDP-4-dehydrorhamnose 3,5-epimerase rmlC Rv3465 TR:O06330 (EMBL:Z95390) (202 aa), Fasta scores: E(): 0, 75.4% identity in 199 aa overlap, and to many others e.g. Streptomyces griseus DTDP-4-dehydrorhamnose 3,5-epimerase SW:STRM_STRGR (P29783) (200 aa), Fasta scores: E(): 0, 45.6% identity in 193 aa overlap. Contains Pfam match to entry PF00908 dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase.;UniProt_AC=Q9X7A4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2388284	2390263	.	+	0	Locus=ML1998;Name=ML1998;Function=;Product=PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN;Comments=ML1998, len: 659 aa. Probable conserved integral membrane protein. Similar to M. tuberculosis membrane protein Rv0102 SW:Y102_MYCTU (Q10897) (661 aa), Fasta scores: E(): 0, 70.2% identity in 662 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=P53525;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2411322	2412236	.	+	0	Locus=ML2020;Name=ML2020;Function=;Product=conserved hypothetical protein;Comments=ML2020, len: 304 aa. Conserved hypothetical protein. Similar to M. tuberculosis conserved hypothetical protein Rv1896c TR:O07736 (EMBL:Z97193) (303 aa), Fasta scores: E(): 0, 78.0% identity in 300 aa overlap, and to many other M. tuberculosis hypothetical proteins e.g. Rv3399 SW:YX99_MYCTU (Z77165) (348 aa), Fasta scores: E(): 0, 41.4% identity in 304 aa overlap. Also similar to ML2640 and ML2539 from M. leprae.;UniProt_AC=Q9CBG0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3063270	3063896	.	-	0	Locus=ML2568c;Name=ML2568c;Function=;Product=POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY);Comments=ML2568c, len: 208 aa. Possible transcriptional regulatory protein (TetR-family). Similar to several putative transcriptional regulators e.g. Mycobacterium tuberculosis Rv0238 TR:O53661 (EMBL:AL021929) fasta scores: E(): 0, 80.9% id in 199 aa, and to Streptomyces coelicolor TR:CAB77290 (EMBL:AL160312) fasta scores: E(): 2.7e-20, 39.0% identity in 205 aa. Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family.;UniProt_AC=O69500;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2441104	2442111	.	-	0	Locus=ML2053c;Name=adhA;Function=;Product=Probable alcohol dehydrogenase AdhA;Comments=ML2053c, len: 335 aa. Probable adhA, alcohol dehydrogenase (EC 1.1.1.1). Similar to Mycobacterium tuberculosis adhA or Rv1862 or MTCY359.11 TR:P95153 (EMBL:Z83859) (346 aa) fasta scores: E(): 0, 84.5% identity in 336 aa. Similar to Rhizobium meliloti alcohol dehydrogenase adhA SW:ADHA_RHIME (O31186) (340 aa) fasta scores: E(): 6.3e-26, 33.1% identity in 344 aa and many putative alcohol dehydrogenases. Also similar to ML1730, ML1784 and ML2025 from M. leprae. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains PS00059 Zinc-containing alcohol dehydrogenases signature.;UniProt_AC=Q9CBF1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2448429	2449829	.	+	0	Locus=ML2061;Name=ndh;Function=;Product=PROBABLE NADH DEHYDROGENASE NDH;Comments=ML2061, len: 466 aa. Probable ndh, NADH dehydrogenase (EC 1.6.99.3). Similar to Mycobacterium tuberculosis hypothetical 49.6 kda protein TR:P95160 (EMBL:Z83859) fasta scores: E(): 0, 90.2% in 460 aa, and to Corynebacterium glutamicum NADH dehydrogenase TR:Q9X710 (EMBL:AJ238250) fasta scores: E(): 0, 56.5% in 455 aa. Contains Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase.;UniProt_AC=O32907;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2458003	2460198	.	+	0	Locus=ML2069;Name=glcB;Function=;Product=PROBABLE MALATE SYNTHASE G GLCB;Comments=ML2069, len: 731 aa. Probable glcB, malate synthase G (EC 4.1.3.2). Similar to Mycobacterium tuberculosis probable malate synthase g SW:MASZ_MYCTU (Q50596) fasta scores: E(): 0, 82.4% in 729 aa, and to Escherichia coli malate synthase g SW:MASZ_ECOLI () fasta scores: E(): 0, 56.9% in 731 aa.;UniProt_AC=O32913;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2481551	2482855	.	-	0	Locus=ML2088c;Name=ML2088c;Function=;Product=putative cytochrome p450;Comments=ML2088c, len: 434 aa. Putative cytochrome p450. Similar to several e.g. Q9X8Q3|AL049754 Streptomyces coelicolor putative cytochrome p-450 hydroxylase (411 aa), fasta scores: E(): 0, (37.4% in 401 aa), and to Rv1880c|YI80_MYCTU|O08464 Mycobacterium tuberculosis putative cytochrome p450 (438 aa), fasta scores: E(): 0, (38.0% in 416 aa). And to BIOI_BACSU|P53554 Bacillus subtilis biotin biosynthesis; cytochrome p450-like enzyme (395 aa), fasta scores: E(): 0, (37.1% in 383 aa). Contains Pfam match to entry PF00067 p450, Cytochrome P450. BELONGS TO THE CYTOCHROME P450 FAMILY.;UniProt_AC=Q9CBE7;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2559343	2560992	.	+	0	Locus=ML2157;Name=ercC3;Function=;Product=PROBABLE DNA HELICASE ERCC3;Comments=ML2157, len: 549 aa. Probable ercC3, DNA helicase (EC 3.6.1.-). Similar to Mycobacterium tuberculosis putative DNA helicase Rv0861c|TR:O53873 (EMBL:AL022004) fasta scores: E(): 0, 91.1% in 542 aa, and to Saccharomyces cerevisiae DNA repair helicase RAD25 SW:RA25_YEAST (Q00578) fasta scores: E(): 0, 29.3% in 611 aa. Contains Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain.;UniProt_AC=Q9CBE0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2472094	2472714	.	-	0	Locus=ML2081c;Name=pgsA2;Function=THOUGHT TO BE INVOLVED IN CARDIOLIPIN BIOSYNTHESIS; GENERATES CARDIOLIPIN FROM PHOSPHATIDYLGLYCEROL AND CDP-DIACYLGLYCEROL [CATALYTIC ACTIVITY : MAY BE: PHOSPHATIDYLGLYCEROL + PHOSPHATIDYLGLYCEROL -> CARDIOLIPIN + GLYCEROL, OR: CDP-DIACYLGLYCEROL + GLYCEROL 3-PHOSPHATE = CMP + 3-(3-PHOSPHATIDYL)-GLYCEROL 1-PHOSPHATE].;Product=PROBABLECDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE PGSA2 (PGP SYNTHASE) (PHOSPHATIDYLGLYCEROPHOSPHATE SYNTHASE) (3-PHOSPHATIDYL-1'-GLYCEROL-3'PHOSPHATE SYNTHASE);Comments=ML2081c, len: 206 aa. Probable pgsA2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase (EC 2.7.8.5). Similar to Mycobacterium tuberculosis putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl- transferase SW:PGSA_MYCTU (Q50611) fasta scores: E(): 0, 76.6% in 205 aa, and to Escherichia coli CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase SW:PGSA_ECOLI (P06978) fasta scores: E(): 4.5e-11, 30.5% in 177 aa. Also similar to ML0979 from M. leprae. Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. Contains PS00379 CDP-alcohol phosphatidyltransferases signature.;UniProt_AC=O32921;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2490070	2491029	.	-	0	Locus=ML2094c;Name=pstC2;Function=;Product=PHOSPHATE-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER PSTC2;Comments=ML2094c, len: 319 aa. Probable pstC2, phosphate-transport integral membrane ABC transporter. Similar to Mycobacterium tuberculosis phosphate transport system integral membrane ABC transporter pstc2 Rv0929 TR:O86344 (EMBL:Z47983) fasta scores: E(): 0, 83.0% in 317 aa, and to Escherichia coli phosphate transport system permease protein pstc SW:PSTC_ECOLI (P07653) fasta scores: E(): 1.7e-30, 33.9% in 304 aa. Also similar to ML2191c a possible pseudogene similar to M. tuberculosis pstC2. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign.;UniProt_AC=Q50098;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2531621	2532916	.	-	0	Locus=ML2130c;Name=gltA2;Function=;Product=PROBABLE CITRATE SYNTHASE I GLTA2;Comments=ML2130c, len: 431 aa. Probable gltA2, citrate synthase 1 (EC 4.1.3.7). Similar to Mycobacterium tuberculosis citrate synthase 1 Rv0896 SW:CISY_MYCTU (Q10530) fasta scores: E(): 0, 91.0% in 431 aa, and to Corynebacterium glutamicum citrate synthase SW:CISY_CORGL (P42457) fasta scores: E(): 0, 62.7% in 432 aa. Contains Pfam match to entry PF00285 citrate_synt, Citrate synthase. Contains PS00480 Citrate synthase signature.;UniProt_AC=O33066;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2524876	2526216	.	+	0	Locus=ML2124;Name=prrB;Function=;Product=TWO COMPONENT SENSOR HISTIDINE KINASE PRRB;Comments=ML2124, len: 446 aa. Probable prrB, two component sensor histidine kinase (EC 2.7.3.-). Similar to Mycobacterium tuberculosis probable sensor-like histidine kinase Rv0902c SW:Y902_MYCTU (Q10560) fasta scores: E(): 0, 92.4% in 446 aa, and to Escherichia coli sensor protein cpxa SW:CPXA_ECOLI (P08336) fasta scores: E(): 7e-14, 28.9% in 301 aa. Contains Pfam match to entry PF00672 DUF5, Domain found in bacterial signal proteins. Contains Pfam match to entry PF00512 signal, Histidine kinase.;UniProt_AC=O33071;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	3102980	3103534	.	+	0	Locus=ML2598;Name=ML2598;Function=;Product=PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN;Comments=ML2598, len: 184 aa. Probable conserved Mce associated membrane protein. Similar to Mycobacterium tuberculosis MCE associated membrane protein Rv0178 TR:O07422 (EMBL:Z97050) fasta scores: E(): 0, 65.6% identity in 244 aa. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CD05;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2588604	2589557	.	-	0	Locus=ML2177c;Name=ML2177c;Function=Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. {Catalytic activity: Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate].;Product=probable uridine phosphorylase;Comments=ML2177c, len: 317 aa. Probable uridine phosphorylase (EC 2.4.2.3), similar to P52624|UDP1_MOUSE Mus musculus uridine phosphorylase (311 aa), fasta scores: E(): 1.9e-21, (34.0% in 268 aa), and to Q16831|UDP1_HUMAN Homo sapiens uridine phosphorylase (310 aa), fasta scores: E(): 2.2e-19, (32.4% in 275 aa). Contains PS01232 Purine and other phosphorylases family 1 signature.;UniProt_AC=Q9CBD1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2606838	2608127	.	-	0	Locus=ML2192c;Name=pstS4;Function=;Product=Probable phosphate-binding protein 4 precursor PstS4;Comments=ML2192c, len: 429 aa. Probable pstS4, phosphate-binding protein 4 precursor, similar to several mycobacterial phosphate-binding proteins e.g. Q9KK89|PST3_MYCAV Phosphate-binding protein 3 precursor (369 aa), fasta scores: E(): 6.9e-63, (47.011% identity in 368 aa overlap) and Rv0928|O86343|PST3_MYCTU Phosphate-binding protein 3 precursor  (370 aa), fasta score: E(): 1.3e-62, (46.505% identity in 372 aa overlap), and to PSTS_ECOLI|P06128|P76744 Escherichia coli phosphate-binding periplasmic protein precursor  (346 aa), fasta scores: E(): 1.3e-20, (27.9% in 344 aa). Also similar to ML2095|Q9CBE5|PST3_MYCLE from M. leprae. Contains Pfam match to entry PF01449 PstS, Phosphate-binding protein. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Note M. tuberculosis does not have pstS3 at this location;UniProt_AC=Q50043;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2619428	2620522	.	-	0	Locus=ML2205c;Name=purM;Function=;Product=PROBABLE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE PURM (AIRS) (PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE) (AIR SYNTHASE);Comments=ML2205c, len: 364 aa. Probable purM, 5'-phosphoribosyl-5-aminoimidazole synthetase (EC 6.3.3.1). Similar to Mycobacterium tuberculosis 5'-phosphoribosyl-5-aminoimidazole synthetase Rv0809 TR:O53823 (EMBL:AL022004) fasta scores: E(): 0, 87.1% identity in 364 aa, and to Bacillus subtilis phosphoribosylformylglycinamidine cyclo-ligase PURM SW:PUR5_BACSU (P12043) fasta scores: E(): 0, 46.4% identity in 334 aa. Contains Pfam match to entry PF00586 AIRS, AIR synthase related protein.;UniProt_AC=Q9CBC2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2626960	2629224	.	-	0	Locus=ML2211c;Name=purL;Function=;Product=PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE II PURL (FGAM SYNTHASE II);Comments=ML2211c, len: 754 aa. purL, phosphoribosylformylglycinamidine synthase II (EC 6.3.5.3). Similar to Mycobacterium tuberculosis phosphoribosylformylglycinamidine synthase II PURL OR Rv0803 OR MTCY07H7A.06C SW:PURL_MYCTU (P54876; O06631) fasta scores: E(): 0, 90.3% identity in 754 aa, and to Bacillus subtilis phosphoribosylformylglycinamidine synthase ii PURL SW:PURL_BACSU (P12042) fasta scores: E(): 0, 43.0% identity in 739 aa. Contains 2 Pfam matches to entry PF00586 AIRS, AIR synthase related protein.;UniProt_AC=Q50023;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2698914	2700140	.	-	0	Locus=ML2276c;Name=ML2276c;Function=;Product=possibleputative FAD-linked oxidoreductase;Comments=ML2276c, len: 408 aa. Possible FAD-linked oxidoreductase. Similar to Mycobacterium tuberculosis putative oxidoreductase Rv0561c or MTCY25D10.40C TR:O06427 (EMBL:Z95558) (408 aa) fasta scores: E(): 0, 84.5% identity in 406 aa. Shows weak similarity to many oxidoreductases e.g. Escherichia coli FixC protein fixC SW:FIXC_ECOLI (P31575; P75626) (428 aa) fasta scores: E(): 1.7e-05, 25.4% identity in 417 aa. Contains Pfam match to entry PF01494 FAD_binding_3, FAD binding domain.;UniProt_AC=Q9CBA6;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2645038	2645931	.	-	0	Locus=ML2227c;Name=purC;Function=;Product=PHOSPHORIBOSYLAMINOIMIDAZOLE- SUCCINOCARBOXAMIDE SYNTHASE PURC (SAICAR SYNTHETASE);Comments=ML2227c, len: 297 aa. purC, phosphoribosylaminoimidazole-succinocarboxamid synthase (EC 6.3.2.6). Similar to Mycobacterium tuberculosis phosphoribosylaminoimidazole-succinocarboxamide synthase PURC OR Rv0780 OR MTCY369.24 SW:PUR7_MYCTU (Q59566; P77904) fasta scores: E(): 0, 81.5% identity in 297 aa, and to Haemophilus influenzae putative phosphoribosylaminoimidazole-succinocarboxamide synthase PURC OR HI1726 SW:PUR7_HAEIN (P43851) fasta scores: E(): 0, 46.0% identity in 287 aa, and to Candida maltosa phosphoribosylamidoimidazole-succinocarboxamide synthase ADE1 SW:PUR7_CANMA (P27602) fasta scores: E(): 0, 45.1% identity in 288 aa. Contains Pfam match to entry PF01259 SAICAR_synt, SAICAR synthetase. Contains PS01057 SAICAR synthetase signature 1. Contains PS01058 SAICAR synthetase signature 2.;UniProt_AC=O08361;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2684496	2684912	.	-	0	Locus=ML2261c;Name=ML2261c;Function=;Product=conserved hypothetical protein;Comments=ML2261c, len: 138 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0546c OR MTCY25D10.25C TR:O06412 (EMBL:Z95558) fasta scores: E(): 0, 84.7% identity in 131 aa. Also some similarity to Haemophilus influenzae lactoylglutathione lyase GLOA OR HI0323 SW:LGUL_HAEIN (P44638) fasta scores: E(): 0.084, 29.1% identity in 127 aa.;UniProt_AC=Q9CBB6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2697290	2698006	.	+	0	Locus=ML2273;Name=menH;Function=;Product=PROBABLE UBIQUINONE/MENAQUINONE BIOSYNTHESIS METHYLTRANSFERASE MENH (2-heptaprenyl-1,4-naphthoquinone methyltransferase);Comments=ML2273, len: 238 aa. Probable menH, ubiquinone/menaquinone biosynthesis methyltransferase (EC 2.1.1.-). Similar to Mycobacterium tuberculosis putative ubiquinone/menaquinone biosynthesis methyltransferase Rv0558 or MTCY25D10.37 TR:O06424 (EMBL:Z95558) (234 aa) fasta scores: E(): 0, 83.3% identity in 228 aa. Similar to many e.g. Streptomyces coelicolor putative ubiquinone/menaquinone methyltransferase SC10A7.27C TR:Q9XAP8 (EMBL:AL078618) (231 aa) fasta scores: E(): 0, 64.9% identity in 225 aa and to Escherichia coli ubiquinone/menaquinone biosynthesis methyltransferase UbiE ubiE SW:UBIE_ECOLI (P27851) (251 aa) fasta scores: E(): 2.7e-19, 42.8% identity in 229 aa. Contains Pfam match to entry PF01209 Ubie_methyltran, ubiE/COQ5 methyltransferase family.;UniProt_AC=Q9CBA8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3104669	3106066	.	-	0	Locus=ML2600c;Name=ML2600c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2600c, len: 465 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 47.6 kda protein Rv0180c TR:O07424 (EMBL:Z97050) fasta scores: E(): 0, 76.7% identity in 447 aa. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CD04;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2702665	2704155	.	-	0	Locus=ML2279c;Name=ML2279c;Function=;Product=Probable transmembrane transport protein;Comments=ML2279c, len: 496 aa. Probable transmembrane transport protein. Similar to the N-terminal part of Mycobacterium tuberculosis transmembrane carbonic anhydrase Rv3273 or MTCY71.13 TR:P96878 (EMBL:Z92771) (764 aa) fasta scores: E(): 0, 59.4% identity in 483 aa. Similar to many putative membrane proteins e.g. Streptomyces coelicolor putative integral membrane protein sch5.25 TR:Q9X927 (EMBL:AL035636) (830 aa) fasta scores: E(): 0, 46.5% identity in 475 aa. Contains Pfam match to entry PF00916 Sulfate_transp, Sulfate transporter family.;UniProt_AC=Q9CBA3;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2730220	2731365	.	+	0	Locus=ML2306;Name=ML2306;Function=;Product=PROBABLE ANION TRANSPORTER ATPASE;Comments=ML2306, len: 381 aa. Probable anion transporter ATPase. Similar to Mycobacterium tuberculosis putative anion transporting ATPase Rv3680 TR:O69648 (EMBL:AL022121) (386 aa) fasta scores: E(): 0, 88.1% identity in 370 aa, and to Streptomyces coelicolor putative ion-transporting ATPase TR:Q9XA35 (EMBL:AL079353) (481 aa) fasta scores: E(): 0, 48.6% identity in 432 aa. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CB87;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2725730	2726491	.	-	0	Locus=ML2301c;Name=nth;Function=HAS BOTH AN APURINIC AND/OR APYRIMIDINIC ENDONUCLEASE ACTIVITY AND A DNA N-GLYCOSYLASE ACTIVITY. INCISES DAMAGED DNA AT CYTOSINES, THYMINES AND GUANINES. ACTS ON A DAMAGED STRAND (OXIDIZED PYRIMIDINES), 5' FROM THE DAMAGED SITE [CATALYTIC ACTIVITY: ENDONUCLEOLYTIC CLEAVAGE NEAR APURINIC OR APYRIMIDINIC SITES TO PRODUCTS WITH 5'-PHOSPHATE].;Product=PROBABLE ENDONUCLEASE III NTH (DNA-(APURINIC OR APYRIMIDINIC SITE)LYASE) (AP LYASE) (AP ENDONUCLEASE CLASS I) (ENDODEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC)) (DEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC));Comments=ML2301c, len: 253 aa. Probable nth, endonuclease III. Similar to Mycobacterium tuberculosis endonuclease III ntH or Rv3674c or MTV025.022C SW:END3_MYCTU (O69642) (245 aa) fasta scores: E(): 0, 89.4% identity in 226 aa. Similar to many e.g. Micrococcus luteus ultraviolet N-glycosylase/ap lyase pdG SW:UVEN_MICLU (P46303) (279 aa) fasta scores: E(): 0, 57.7% identity in 246 aa and to Escherichia coli endonuclease III ntH SW:END3_ECOLI (P20625) (211 aa) fasta scores: E(): 7.6e-24, 36.6% identity in 205 aa. Contains Pfam match to entry PF00730 Endonuclease_3, Endonuclease III. Contains PS01155 Endonuclease III family signature. Contains PS00764 Endonuclease III iron-sulfur binding region signature.;UniProt_AC=Q9CB92;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2884711	2886051	.	-	0	Locus=ML2414c;Name=hemL;Function=;Product=PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT);Comments=ML2414c, len: 446 aa. Probable hemL, glutamate-1-semialdehyde aminotransferase (EC  5.4.3.8). Similar to Mycobacterium tuberculosis glutamate-1-semialdehyde 2,1-aminomutase HemL Rv0524 SW:GSA_MYCTU (O06390) (462 aa) fasta scores: E(): 0, 82.4% identity in 460 aa, and to Escherichia coli glutamate-1-semialdehyde 2,1-aminomutase HemL SW:GSA_ECOLI (P23893; P78277) (426 aa) fasta scores: E(): 0, 53.0% id in 419 aa. Also similar to ML1409 from M. leprae. Contains Pfam match to entry PF00202 aminotran_3, Aminotransferases class-III pyridoxal-phosphate. Contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.;UniProt_AC=P46716;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2277267	2278283	.	-	0	Locus=ML1892c;Name=mkl;Function=;Product=POSSIBLE RIBONUCLEOTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER MKL;Comments=ML1892c, len: 338 aa. Possible mkl, ribonucleotide-transport ATP-binding protein ABC transporter.  Similar to M. tuberculosis ABC transporter Rv0655 SW:MKL_MYCTU (O06784) (359 aa), Fasta scores: E(): 0, 93.2% identity in 336 aa overlap, and to many others e.g. Escherichia coli hypothetical ABC transporter ATP-binding protein SW:YRBF_ECOLI (P45393) (269 aa), Fasta scores: E(): 2.4e-32, 38.9% identity in 252 aa overlap. Also similar to ML0669, ML1424, ML1089, ML2352, ML2189, ML0336, ML1122, ML1113, ML0595, ML1114, ML0590, ML1726 and ML1816 from M. leprae. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.;UniProt_AC=P30769;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2754647	2756470	.	+	0	Locus=ML2324;Name=leuA;Function=INVOLVED IN LEUCINE BIOSYNTHESIS (AT THE FIRST STEP). CATALYZES CONDENSATION OF ACETYL-CoA AND 2-OXOISOVALERATE TO FORM 2-ISOPROPYLMALATE SYNTHASE [CATALYTIC ACTIVITY: 3-CARBOXY-3-HYDROXY-4-METHYLPENTANOATE + CoA = ACETYL-COA + 3-METHYL-2-OXOBUTANOATE + H(2)O].;Product=2-ISOPROPYLMALATE SYNTHASE LEUA (ALPHA-ISOPROPYLMALATE SYNTHASE) (ALPHA-IPM SYNTHETASE);Comments=ML2324, len: 607 aa. leu, 2-isopropylmalate synthase (EC 4.1.3.12). Similar to Mycobacterium tuberculosis 2-isopropylmalate synthase leuA or Rv3710 SW:LEU1_MYCTU (P96420; O69677) (644 aa) fasta scores: E(): 0, 80.7% identity in 642 aa, and to Corynebacterium glutamicum 2-isopropylmalate synthase leuA SW:LEU1_CORGL (P42455) (616 aa) fasta scores: E(): 0, 66.8% identity in 602 aa. Contains Pfam match to entry PF00682 HMGL-like, HMGL-like. Contains PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. Contains PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1.;UniProt_AC=Q9CB76;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2767659	2768939	.	-	0	Locus=ML2336c;Name=ML2336c;Function=;Product=conserved hypothetical protein;Comments=ML2336c, len: 426 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical 44.4 kDa protein Rv3722c TR:O69689 (EMBL:AL022121) (435 aa) fasta scores: E(): 0, 87.6% identity in 396 aa, and to Deinococcus radiodurans conserved hypothetical protein TR:Q9RU17 (EMBL:AE002001) (452 aa) fasta scores: E(): 0, 43.1% identity in 450 aa. Note start changed since first submission.;UniProt_AC=Q9CB73;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2779484	2781682	.	-	0	Locus=ML2341c;Name=ML2341c;Function=;Product=possible transcriptional regulatory protein;Comments=ML2341c, len: 732 aa. Possible transcriptional regulatory protein. The N-terminus of the predicted product of this CDS is similar to many adenylate cyclases e.g. Stigmatella aurantiaca adenylate cyclase 2 CyaB SW:CYAB_STIAU (P40138; O54080) (352 aa) fasta scores: E(): 3.8e-07, 35.9% identity in 192 aa. The C-terminus is similar to many proteins of undefined function and to several proposed regulatory proteins e.g. Streptomyces coelicolor putative regulatory protein TR:Q9Z573 (EMBL:AL035569) (194 aa), BlastP Expect 6.1. Contains Pfam match to entry PF00211 guanylate_cyc, Adenylate and Guanylate cyclase catalytic domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CB72;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	2816101	2821716	.	-	0	Locus=ML2357c;Name=ppsA;Function=;Product=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA;Comments=ML2357c, len: 1871 aa. Probable ppsA, type-I polyketide synthase. Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) fasta scores: E(): 0, 76.1% identity in 1888 aa and to Penicillium patulum 6-methylsalicylic acid synthase SW:MSAS_PENPA (P22367) (1774 aa) fasta scores: E(): 0, 33.8% identity in 1823 aa. Also similar to ML2353, ML2354, ML0139, ML0135, ML2354, ML2355, ML2356, ML1229 and ML0101 from M. leprae. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q9Z5K6;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2305502	2306866	.	+	0	Locus=ML1923;Name=lpqF;Function=;Product=PROBABLE CONSERVED LIPOPROTEIN LPQF;Comments=ML1923, len: 454 aa. Probable lpqF, conserved lipoproteins. Similar to M. tuberculosis lipoprotein Rv3593 lpqF TR:O06155 (EMBL:Z95555) (452 aa), Fasta scores: E(): 0, 79.2% identity in 451 aa overlap, and weakly to several beta-lactamase proteins e.g. Xanthomonas maltophilia chromosomic class A beta-lactamase TR:Q9X5A7 (EMBL:AF123246) (304 aa), Fasta scores: E(): 0.019, 26.2% identity in 260 aa overlap.;UniProt_AC=Q9CBI7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2804876	2811481	.	-	0	Locus=ML2355c;Name=ppsC;Function=;Product=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC;Comments=ML2355c, len: 2201 aa. ppsC, type-I polyketide synthase. Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% identity in 2217 aa. Also similar to ML2353, ML2354, ML0139, ML0135, ML2354, ML2356, ML2357, ML1229 and ML0101 from M. leprae. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl synthases active site.;UniProt_AC=Q49933;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2863244	2863738	.	+	0	Locus=ML2393;Name=greA;Function=NECESSARY FOR EFFICIENT RNA POLYMERASE TRANSCRIPTION ELONGATION PAST TEMPLATE-ENCODED ARRESTING SITES. THE ARRESTING SITES IN DNA HAVE THE PROPERTY OF TRAPPING A CERTAIN FRACTION OF ELONGATING RNA POLYMERASES THAT PASS THROUGH, RESULTING IN LOCKED TERNARY COMPLEXES. CLEAVAGE OF THE NASCENT TRANCRIPT BY CLEAVAGE FACTORS SUCH AS GREA OR GREB ALLOWS THE RESUMPTION OF ELONGATION FROM THE NEW 3'TERMINUS. GREA RELEASES SEQUENCES OF 2 TO 3 NUCLEOTIDES ;Product=PROBABLE TRANSCRIPTION ELONGATION FACTOR GREA (Transcript cleavage factor greA);Comments=ML2393, len: 164 aa. Probable greA, transcription elongation factor G. Similar to Mycobacterium tuberculosis transcription elongation factor Rv1080c SW:GREA_MYCTU (O53428) (164 aa) fasta scores: E(): 0, 94.5% identity in 164 aa, and to Escherichia coli transcription elongation factor GreA SW:GREA_ECOLI (P21346; P78111) (158 aa) fasta scores: E(): 1e-08, 34.6% identity in 159 aa. Contains Pfam match to entry PF01272 GreA_GreB, Prokaryotic transcription elongation factor, GreA/GreB. Contains PS00829 Prokaryotic transcription elongation factors signature 1. Contains PS00830 Prokaryotic transcription elongation factors signature 2.;UniProt_AC=P46808;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2038222	2039808	.	-	0	Locus=ML1692c;Name=serA1;Function=;Product=PROBABLE D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA1 (PGDH);Comments=ML1692c, len: 528 aa. Probable serA1, D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95). Highly similar to many D-3-phosphoglycerate dehydrogenases involved in serine biosynthesis including: Bacillus subtilis SW:SERA_BACSU (P35136) (525 aa), Fasta scores: E(): 0, 36.1% identity in 527 aa overlap and Mycobacterium tuberculosis Rv2996c SW:SERA_MYCTU (O53243) (528 aa), Fasta scores: E(): 0, 89.6% identity in 528 aa overlap. Contains Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases. Contains Pfam match to entry PF01842 ACT, ACT domain. Contains PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. Contains PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3.;UniProt_AC=O33116;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2144256	2145080	.	+	0	Locus=ML1769;Name=uspB;Function=;Product=PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPB;Comments=ML1769, len: 274 aa. Probable uspB, sugar-transport integral membrane protein ABC transporter. Similar to M. tuberculosis Rv2317 TR:P71895 (EMBL:Z79702) uspB, sugar-transport integral membrane protein ABC transporter (274 aa), Fasta scores: E(): 0, 85.0% identity in 274 aa overlap, and to many others e.g. Thermomonospora fusca cellobiose transport permease bglB TR:AAF37729 (EMBL:AF086819) (305 aa), Fasta scores: E(): 1.9e-24, 30.2% identity in 275 aa overlap. Also similar to ML1425 and ML1088 from M. leprae. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Note previously known as uspE.;UniProt_AC=Q9CBN7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2612068	2612901	.	+	0	Locus=ML2198;Name=cysA2;Function=;Product=PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE);Comments=ML2198, len: 277 aa. Probable cysA2, thiosulfate sulfurtransferase (EC 2.8.1.1). Similar to several e.g. Mycobacterium tuberculosis putative thiosulfate sulfurtransferase SW:THTR_MYCTU (O05793) Rv0815c and Rv3117 fasta scores: E(): 0, 85.2% in 277 aa, and to Saccharopolyspora erythraea putative thiosulfate sulfurtransferase SW:THTR_SACER (P16385) fasta scores: E(): 0, 74.1% in 274 aa, and to Corynebacterium glutamicum thiosulfate sulfurtransferase SW:THTR_CORGL (P71121) fasta scores: E(): 0, 44.5% in 218 aa. Also similar to ML0728 from M. leprae. Contains 2 Pfam matches to entry PF00581 Rhodanese, Rhodanese-like domain. Contains PS00683 Rhodanese C-terminal signature.;UniProt_AC=Q50036;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2369809	2372205	.	-	0	Locus=ML1985c;Name=aceA;Function=;Product=PROBABLE ISOCITRATE LYASE AceA (ISOCITRASE) (ISOCITRATASE) (ICL);Comments=ML1985c, len: 798 aa. Probable aceA, isocitrate lyase (EC 4.1.3.1). Previously sequenced as Mycobacterium leprae isocitrate lyase SW:ACEA_MYCLE (P46831) (606 aa), Fasta scores: E(): 0, 99.8% identity in 568 aa overlap. Similar to M. tuberculosis isocitrate lyase N-terminal and C-terminal modules aceAa Rv1915 TR:O07718 (EMBL:Z97193) (367 aa), Fasta scores: E(): 0, 87.1% identity in 295 aa overlap and aceAb Rv1916 TR:O07717 (EMBL:Z97193) (398 aa), Fasta scores: E(): 0, 87.9% identity in 397 aa overlap, and to many others e.g. Coprinus cinereus isocitrate lyase SW:ACEA_COPCI (O13439) (537 aa), Fasta scores: E(): 0, 38.1% identity in 586 aa overlap. Contains 2 Pfam matches to entry PF00463 ICL, Isocitrate lyase. Contains PS00161 Isocitrate lyase signature.;UniProt_AC=P46831;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1997451	1998872	.	+	0	Locus=ML1657;Name=accD6;Function=;Product=ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6;Comments=ML1657, len: 473 aa. Probable accD6, acetyl/propionyl CoA carboxylase [beta] subunit (EC 6.4.1.3). Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (476 aa), Fasta scores: E(): 0, 70.9% identity in 477 aa overlap and Mycobacterium tuberculosis Rv2247 SW:PCCB_MYCTU (Q10506) (473 aa), Fasta scores: E(): 0, 92.8% identity in 473 aa overlap. Also similar to ML0731 from M. leprae. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O69472;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1989171	1991981	.	+	0	Locus=ML1651;Name=aceE;Function=;Product=Probable pyruvate dehydrogenase E1 component aceE (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE);Comments=ML1651, len: 936 aa. Probable aceE, pyruvate dehydrogenase E1 component (EC 1.2.4.1). Highly similar to many pyruvate dehydrogenases including: Escherichia coli pyruvate dehydrogenase E1 component SW:ODP1_ECOLI (P06958) (886 aa), Fasta scores: E(): 0, 51.3% identity in 892 aa overlap and Mycobacterium tuberculosis Rv2241 SW:ODP1_MYCTU (Q10504) (901 aa), Fasta scores: E(): 0, 89.5% identity in 904 aa overlap.;UniProt_AC=Q9CBS8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2693812	2695482	.	+	0	Locus=ML2270;Name=menD;Function=INVOLVED IN MENAQUINONE BIOSYNTHESIS (AT THE FIRST STEP) [CATALYTIC ACTIVITY 1: ISOCHORISMATE + 2-KETOGLUTARATE = 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE + PYRUVATE + CO(2)] [CATALYTIC ACTIVITY 2: 2-OXOGLUTARATE = SUCCINATE SEMIALDEHYDE + CO(2)].;Product=PROBABLE BIFUNCTIONAL MENAQUINONE BIOSYNTHESIS PROTEIN MEND : 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE (SHCHC SYNTHASE) + 2-OXOGLUTARATE DECARBOXYLASE (ALPHA- KETOGLUTARATE DECARBOXYLASE) (KDC);Comments=ML2270, len: 556 aa. Probable menD, menaquinone biosynthesis protein, including 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.1.3.-) and 2-oxoglutarate decarboxylase (EC 4.1.1.71) activities. Similar to Mycobacterium tuberculosis menD or Rv0555 or MTCY25D10.34 TR:O06421 (EMBL:Z95558) (554 aa) fasta scores: E(): 0, 85.4% identity in 556 aa. Similar to Bacillus subtilis menaquinone biosynthesis protein MenD (includes 2-succinyl-6-hydroxy- 2,4-cyclohexadiene-1-carboxylate synthase, 2-oxoglutarate decarboxylase) menD SW:MEND_BACSU (P23970; P23969; O34492) (580 aa) fasta scores: E(): 2.9e-21, 31.6% identity in 594 aa.;UniProt_AC=Q9CBB0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2087923	2089011	.	+	0	Locus=ML1730;Name=adhC;Function=;Product=PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC;Comments=ML1730, len: 362 aa. Probable adhC, NADP-dependent alcohol dehydrogenase (EC 1.1.1.2). Highly similar to many Prokaryotic and Eukaryotic dehydrogenases including: Mycobacterium tuberculosis Rv3045 SW:ADH_MYCTU (P31975) (346 aa), Fasta scores: E(): 0, 85.8% identity in 346 aa overlap and Arabidopsis thaliana SW:CAD1_ARATH (P42734) (360 aa), Fasta scores: E(): 0, 48.8% identity in 344 aa overlap. Also similar to ML2053 from M. leprae. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains PS00059 Zinc-containing alcohol dehydrogenases signature. Note previously known as adhA.;UniProt_AC=Q9CBQ3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2751631	2752686	.	-	0	Locus=ML2322c;Name=asd;Function=INVOLVED AT THE SECOND STEP IN THE COMMON BIOSYNTHETIC PATHWAY LEADING FROM ASP TO THE CELL WALL PRECURSOR MESO-DIAMINOPIMELATE, TO LYS, TO MET, TO ILE AND TO THR [CATALYTIC ACTIVITY: L-ASPARTATE-SEMIALDEHYDE + ORTHOPHOSPHATE + NADP(+) = L-ASPARTYL PHOSPHATE + NADPH].;Product=ASPARTATE-SEMIALDEHYDE DEHYDROGENASE ASD (ASA DEHYDROGENASE) (ASADH) (ASPARTIC SEMIALDEHYDE DEHYDROGENASE) (L-ASPARTATE-BETA-SEMIALDEHYDE DEHYDROGENASE);Comments=ML2322c, len: 351 aa. asd, aspartate semialdehyde dehydrogenase (EC 1.2.1.11). Similar to Mycobacterium tuberculosis aspartate-semialdehyde dehydrogenase Rv3708c SW:DHAS_MYCTU (345 aa) fasta scores: E(): 0, 84.4% identity in 347 aa, and to Mycobacterium bovis aspartate-semialdehyde dehydrogenase SW:DHAS_MYCBO (345 aa) fasta scores: E(): 0, 82.1% identity in 347 aa. Contains Pfam match to entry PF01118 Semialdhyde_dh, Semialdehyde dehydrogenase. Contains PS01103 Aspartate-semialdehyde dehydrogenase signature.;UniProt_AC=Q9CB78;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2084630	2086354	.	-	0	Locus=ML1728c;Name=ctaD;Function=CYTOCHROME C OXIDASE IS THE COMPONENT OF THE RESPIRATORY CHAIN THAT CATALYZES THE REDUCTION OF OXYGEN TO WATER. SUBUNITS 1-3 FORM THE FUNCTIONAL CORE OF THE ENZYME COMPLEX. CO I IS THE CATALYTIC SUBUNIT OF THE ENZYME. ELECTRONS ORIGINATING IN CYTOCHROME C ARE TRANSFERRED VIA THE COPPER A CENTER OF SUBUNIT 2 AND HEME A OF SUBUNIT 1 TO THE BIMETALLIC CENTER FORMED BY HEME A3 AND COPPER B  [CATALYTIC ACTIVITY: 4 FERROCYTOCHROME C + O(2) = 2 H(2)O + 4 FERRICYTOCHROME C].;Product=PROBABLE CYTOCHROME C OXIDASE POLYPEPTIDE I CTAD (CYTOCHROME AA3 SUBUNIT 1);Comments=ML1728c, len: 574 aa. Probable ctaD, cytochrome C oxidase, polypeptide I (EC 1.9.3.1). Highly similar to many cytochrome C oxidases including: Bacillus firmus SW:COX1_BACFI (Q04440) (624 aa), Fasta scores: E(): 0, 51.9% identity in 522 aa overlap and Mycobacterium tuberculosis Rv3043c SW:COX1_MYCTU (O53290) (573 aa), Fasta scores: E(): 0, 95.4% identity in 566 aa overlap. Contains Pfam match to entry PF00115 COX1, Cytochrome C and Quinol oxidase polypeptide I. Contains PS00077 Heme-copper oxidase catalytic subunit.;UniProt_AC=Q9CBQ5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2793929	2794924	.	-	0	Locus=ML2352c;Name=drrA;Function=PROBABLY INVOLVED IN ACTIVE TRANSPORT OF ANTIBIOTIC AND PHTHIOCEROL DIMYCOCEROSATE (DIM) ACROSS THE MEMBRANE (EXPORT). DRRA, DRRB|Rv2936|MTCY19H9.05 AND DRRC|Rv2938|MTCY19H9.06 MAY ACT JOINTLY TO CONFER DAUNORUBICIN AND DOXORUBICIN RESISTANCE BY AN EXPORT MECHANISM. RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM.;Product=PROBABLE DAUNORUBICIN-DIM-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER DRRA;Comments=ML2352c, len: 331 aa. Probable drrA, daunorubicin-DIM-transport resistance ATP-binding protein ABC transporter, probably involved in daunorubicin resistance and phthiocerol dimycocerosate transport. Similar to several antibiotic resistant proteins including: Mycobacterium tuberculosis Rv2936 TR:P96205 (EMBL:Z83857) (331 aa) fasta scores: E(): 0, 85.2% identity in 331 aa and Streptomyces peucetius daunorubicin resistance ATP-binding protein DrrA SW:DRRA_STRPE (P32010) (330 aa) fasta scores: E(): 0, 46.0% identity in 322 aa. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.;UniProt_AC=Q49938;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1943808	1945373	.	-	0	Locus=ML1622c;Name=ffh;Function=;Product=PROBABLE SIGNAL RECOGNITION PARTICLE PROTEIN FFH (FIFTY-FOUR HOMOLOG) (SRP PROTEIN);Comments=ML1622c, len: 521 aa. Probable ffh, signal recognition particle protein. Highly similar to many signal recognition particle proteins, involved in the reconition of the signal sequence and the efficient export of the protein, including: Bacillus subtilis SW:SR54_BACSU (P37105) (446 aa), Fasta scores: E(): 0, 51.0% identity in 435 aa overlap and Mycobacterium tuberculosis Rv2916c SW:SR54_MYCTU (Q10963) (525 aa), Fasta scores: E(): 0, 87.8% identity in 526 aa overlap. Contains Pfam match to entry PF00448 SRP54, SRP54-type protein. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O33013;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2053124	2054617	.	-	0	Locus=ML1702c;Name=gatA;Function=COMPONENT OF THE TRANSLATIONAL APPARATUS. FURNISHES A MEANS FOR FORMATION OF CORRECTLY CHARGED GLN-TRNA(GLN) THROUGH THE TRANSAMIDATION OF MISACYLATED GLU-TRNA(GLN) IN ORGANISMS WHICH LACK GLUTAMINYL-TRNA SYNTHETASE. THE REACTION TAKES PLACE IN THE PRESENCE OF GLUTAMINE AND ATP THROUGH AN ACTIVATED GAMMA-PHOSPHO-GLU-TRNA(GLN) [CATALYTIC ACTIVITY: ATP + L-GLUTAMYL-TRNA(GLN) + L-GLUTAMINE = ADP + PHOSPHATE + L-GLUTAMINYL-TRNA(GLN) + L-GLUTAMATE].;Product=PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A);Comments=ML1702c, len: 497 aa. Probable gatA, glutamyl-tRNA(Gln) amidotransferase, subunit A (EC 6.3.5.-). Highly similar to many glutamyl-tRNA(Gln) amidotransferases (subunit A) including: Bacillus subtilis SW:GATA_BACSU (O06491) (485 aa), Fasta scores: E(): 0, 50.8% identity in 476 aa overlap and Mycobacterium tuberculosis Rv3011c SW:GATA_MYCTU (O53258) (494 aa), Fasta scores: E(): 0, 88.5% identity in 494 aa overlap. Contains Pfam match to entry PF01425 Amidase, Amidase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE AMIDASE FAMILY;UniProt_AC=O33105;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2463426	2466284	.	-	0	Locus=ML2072c;Name=gcvB;Function=THE GLYCINE CLEAVAGE SYSTEM CATALYSES THE DEGRADATION OF GLYCINE. THE P PROTEIN BINDS THE ALPHA-AMINO GROUP OF GLYCINE THROUGH ITS PYRIDOXAL PHOSPHATE COFACTOR; CO(2) IS RELEASED AND THE REMAINING METHYLAMINE MOIETY IS THEN TRANSFERRED TO THE LIPOAMIDE COFACTOR OF THE H PROTEIN [CATALYTIC ACTIVITY : GLYCINE + LIPOYLPROTEIN = S- AMINOMETHYLDIHYDROLIPOYLPROTEIN + CO(2)];Product=Probable glycine dehydrogenase GcvB (Glycine decarboxylase) (Glycine cleavage system P-protein);Comments=ML2072c, len: 952 aa. Probable gcvB, glycine decarboxylase (EC 1.4.4.2). Similar to Mycobacterium tuberculosis probable glycine dehydrogenase [decarboxylating] SW:GCSP_MYCTU (Q50601) fasta scores: E(): 0, 84.7% in 942 aa, and to Escherichia coli glycine dehydrogenase [decarboxylating] SW:GCSP_ECOLI (P33195) fasta scores: E(): 0, 53.5% in 956 aa.;UniProt_AC=O32915;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2700171	2701163	.	+	0	Locus=ML2277;Name=grcC1;Function=;Product=PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE);Comments=ML2277, len: 330 aa. Probable grcC1, polyprenyl diphosphate synthase (EC 2.5.1.-). Similar to Mycobacterium tuberculosis polyprenyl diphosphate synthase Rv0562 or MTCY25D10.41 TR:O06428 (EMBL:Z95558) (335 aa) fasta scores: E(): 0, 76.4% identity in 335 aa and to Mycobacterium tuberculosis isoprene biosynthesis transferase Rv0989c or MTCI237.03C TR:O05572 (EMBL:Z94752) (325 aa) fasta scores: E(): 0, 53.6% identity in 323 aa. Similar to many polyprenyl synthase components e.g. Bacillus stearothermophilus heptaprenyl diphosphate synthase component ii hepT or heps-2 SW:HEP2_BACST (P55785) (320 aa) fasta scores: E(): 1.2e-31, 33.8% id in 320 aa. Contains Pfam match to entry PF00348 polyprenyl_synt, Polyprenyl synthetases. Contains PS00444 Polyprenyl synthetases signature 2.;UniProt_AC=Q9CBA5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2453707	2455143	.	+	0	Locus=ML2066;Name=guaB1;Function=;Product=PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD);Comments=ML2066, len: 478 aa. Probable guaB1, inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205). Previously sequenced as TR:O32912 (EMBL:AL008609) fasta scores: E(): 0, 100.0% in 478 aa. Similar to Mycobacterium tuberculosis inosine-5'-monophosphate dehydrogenase Rv1843c SW:YI43_MYCTU (Q50591) fasta scores: E(): 0, 86.4% in 478 aa, and to Bacillus subtilis inosine-5'-monophosphate dehydrogenase SW:IMDH_BACSU (P21879) fasta scores: E(): 0, 37.7% in 472 aa. Also similar to ML0387 and ML0388 from M. leprae. Contains 2 Pfam matches to entry PF00571 CBS, CBS domain. Contains Pfam match to entry PF00478 IMPDH_C, IMP dehydrogenase / GMP reductase C terminus. Contains Pfam match to entry PF01574 IMPDH_N, IMP dehydrogenase / GMP reductase N terminus.;UniProt_AC=O32912;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2220221	2220766	.	-	0	Locus=ML1832c;Name=kad;Function=THIS SMALL UBIQUITOUS ENZYME IS ESSENTIAL IN INTRACELLULAR NUCLEOTIDE METABOLISM, IN ADDITION IT HAS BEEN FOUND TO ACTS AS BOTH A NUCLEOSIDE MONO- AND DI-PHOSPHATE KINASE SUGGESTING IT MAY HAVE A ROLE IN RNA AND DNA BIOSYNTHESIS [CATALYTIC ACTIVITY: ATP + AMP = ADP + ADP].;Product=PROBABLE ADENYLATE KINASE KAD (ATP-AMP TRANSPHOSPHORYLASE);Comments=ML1832c, len: 181 aa. Probable kad, adenylate kinase (EC 2.7.4.3). Similar to M. tuberculosis adenylate kinase kad Rv0733 SW:KAD_MYCTU (O53796) (181 aa), Fasta scores: E(): 0, 83.4% identity in 181 aa overlap, and to many thers e.g. Bacillus subtilis adenylate kinase SW:KAD_BACSU (P16304) (217 aa), Fasta scores: E(): 2.9e-20, 39.3% identity in 211 aa overlap. Contains Pfam match to entry PF00406 adenylatekinase, Adenylate kinase. Contains PS00113 Adenylate kinase signature.;UniProt_AC=O33007;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2005139	2005612	.	-	0	Locus=ML1663c;Name=kdtB;Function=INVOLVED IN THE COENZYME A (CoA) BIOSYNTHESIS (AT THE FOURTH STEP). REVERSIBLY TRANSFERS AN ADENYLYL GROUP FROM ATP TO 4'-PHOSPHOPANTETHEINE, YIELDING DEPHOSPHO-CoA (DPCOA) AND PYROPHOSPHATE [CATALYTIC ACTIVITY: ATP + PANTETHEINE 4'-PHOSPHATE = DIPHOSPHATE + DEPHOSPHO-CoA].;Product=PROBABLE PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE KDTB (PANTETHEINE- PHOSPHATE ADENYLYLTRANSFERASE) (PPAT) (DEPHOSPHO-CoA PYROPHOSPHORYLASE);Comments=ML1663c, len: 157 aa.  Probable kdtB (alternate gene name: coaD), phosphopantetheine adenylyltransferase (EC 2.7.7.3). Highly similar to many phosphopantetheine adenylyltransferases  involved in coenzyme A biosynthesis, including: Escherichia coli SW:COAD_ECOLI (P23875) (159 aa), Fasta scores: E(): 5.9e-25, 43.5% identity in 154 aa overlap and Mycobacterium tuberculosis Rv2965c SW:COAD_MYCTU (Q50452) (161 aa), Fasta scores: E(): 0, 85.6% identity in 153 aa overlap. Contains Pfam match to entry PF01467 Cytidylyltransf, Cytidylyltransferase. Note previously known as coaD.;UniProt_AC=O69466;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2856888	2858291	.	+	0	Locus=ML2387;Name=lpd;Function=;Product=DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE);Comments=ML2387, len: 467 aa. Probable lpd, dihydrolipoamide dehydrogenase. Highly similar to many dihydrolipoamide dehydrogenases including: Mycobacterium tuberculosis Rv0462 TR:O53747 (EMBL:AL021933) (464 aa) fasta scores: E(): 0, 83.1% identity in 467 aa and Bacillus subtilis SW:DLD2_BACSU (P54533) (474 aa) fasta scores: E(): 0, 43.2% identity in 477 aa. Contains Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. Contains PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.;UniProt_AC=Q50068;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2082428	2083345	.	-	0	Locus=ML1726c;Name=ML1726c;Function=;Product=PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER;Comments=ML1726c, len: 305 aa. Probable conserved ATP-binding protein ABC transporter. Highly similar to many putative ABC transport, ATP-binding proteins including: Streptomyces coelicolor TR:CAB76322 (EMBL:AL158060) (279 aa), Fasta scores: E(): 0, 44.4% identity in 277 aa overlap and Mycobacterium tuberculosis Rv3041c TR:O53288 (EMBL:AL021287) (287 aa), Fasta scores: E(): 0, 83.4% identity in 289 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS). ;UniProt_AC=Q9CBQ7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2115128	2116999	.	-	0	Locus=ML1750c;Name=ML1750c;Function=;Product=conserved hypothetical protein;Comments=ML1750c, len: 623 aa. Conserved hypothetical protein. The C-terminus of this protein is highly similar to many including several hypothetical proteins and putative phosphodiesterases e.g. Mycobacterium tuberculosis Rv1354c SW:YD54_MYCTU (Q11024) (623 aa), Fasta scores: E(): 0, 63.3% identity in 605 aa overlap and Streptomyces coelicolor TR:Q9Z584 (EMBL:AL035569) (746 aa), Fasta scores: E(): 0, 40.0% identity in 455 aa overlap. The C-terminus of the predicted product of this CDS is similar to ML1752 from M. leprae. Contains Pfam match to entry PF00990 DUF9, Domain of unknown function. Contains Pfam match to entry PF00563 DUF2, Domain of unknown function 2. Contains Pfam match to entry PF01590 GAF, GAF domain.;UniProt_AC=Q9CBP6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2358459	2360177	.	+	0	Locus=ML1974;Name=ML1974;Function=;Product=POSSIBLE CONSERVED PERMEASE;Comments=ML1974, len: 572 aa. Possible conserved permease. Similar to M. tuberculosis probable permease Rv1979c SW:YJ79_MYCTU (Q10875) (481 aa), Fasta scores: E(): 0, 76.8% identity in 462 aa overlap, and to e.g. Arabidopsis thaliana putative amino acid transporter TR:Q9SQZ0 (EMBL:AC011560) (584 aa), Fasta scores: E(): 2.1e-13, 23.0% identity in 508 aa overlap. Also similar to ML1304 and ML1305 from M. leprae. Contains Pfam match to entry PF00324 aa_permeases, Amino acid permease. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CBH5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2284613	2285473	.	+	0	Locus=ML1900;Name=mmaA1;Function=INVOLVED IN MYCOLIC ACIDS MODIFICATION. CATALYZES UNUSUAL S-ADENOSYL-METHIONINE-DEPENDENT TRANSFORMATION OF A CIS-OLEFIN MYCOLIC ACID INTO A SECONDARY ALCOHOL. CATALYZES INTRODUCTION OF A HYDROXYL GROUP AT THE DISTAL POSITION ON MYCOLIC ACID CHAINS TO PRODUCE THE HYDROXYL MYCOLATE. Mycolic acids represent a major constituent of the mycobacterial cell wall complex. Methyl transfer results in formation of a secondary hydroxy group with an adjacent methyl branch; Olefinic mycolic acid methyl transferase.;Product=METHOXY MYCOLIC ACID SYNTHASE 1 MMAA1 (METHYL MYCOLIC ACID SYNTHASE 1) (MMA1) (HYDROXY MYCOLIC ACID SYNTHASE);Comments=ML1900, len: 286 aa. Probable mmaA1, methyl mycolic acid synthase 1 (EC 2.1.1.-). Similar to M. tuberculosis methyl mycolic acid synthase 1 Rv0645c TR:P94922 (EMBL:U77466) (286 aa), Fasta scores: E(): 0, 87.4% identity in 286 aa overlap, and to many others e.g. M. tuberculosis cyclopropane-fatty-acyl-phospholipid synthase 1 SW:CFA1_MYCTU (Q11195) (287 aa), Fasta scores: E(): 0, 54.9% identity in 284 aa overlap. Also similar to ML2459, ML2426 and ML2334 from M. leprae.;UniProt_AC=Q9CBK4;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2922797	2923900	.	-	0	Locus=ML2447c;Name=murB;Function=;Product=PROBABLE UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE MURB (UDP-N-ACETYLMURAMATE DEHYDROGENASE);Comments=ML2447c, len: 367 aa. Probable murA, UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.1.1.158). Similar to Mycobacterium tuberculosis UDP-N-acetylenolpyruvoylglucosamine reductase Rv0482 SW:MURB_MYCTU (Q11148) fasta scores: E(): 0, 79.0% identity in 372 aa, and to Escherichia coli UDP-N-acetylenolpyruvoylglucosamine reductase MurB SW:MURB_ECOLI (P08373) fasta scores: E(): 3.6e-12, 35.5% identity in 352 aa. Contains Pfam match to entry PF02215 MurB, UDP-N-acetylenolpyruvoylglucosamine reductase.;UniProt_AC=Q9CB48;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2846834	2849713	.	+	0	Locus=ML2378;Name=mmpL4;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL4;Comments=ML2378, len: 959 aa. Probable mmpL4, conserved transmembrane protein. Similar to many membrane proteins including: Mycobacterium tuberculosis membrane protein MmpL4 or Rv0450c SW:MML4_MYCTU (O53735) (967 aa) fasta scores: E(): 0, 78.4% identity in 962 aa, and to Mycobacterium avium TmtpB TR:Q9XCF5 (EMBL:AF143772) (963 aa) fasta scores: E(): 0, 61.8% identity in 945 aa. Also similar to ML0259 a possible pseudogene similar to M. tuberculosis mmpL4. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=P54881;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2160282	2161367	.	+	0	Locus=ML1784;Name=mscR;Function=;Product=Probable S-nitrosomycothiol reductase MscR;Comments=ML1784, len: 361 aa. Probable mscR, S-nitrosomycothiol reductase. Similar to M. tuberculosis mscR Rv2259 TR:O53533 (EMBL:AL021925) (361 aa), Fasta scores: E(): 0, 88.9% identity in 361 aa overlap, and to other alcohol dehydrogenases e.g. Amycolatopsis methanolica NAD/mycothiol-dependent formaldehyde dehydrogenase SW:FADH_AMYME (P80094) (360 aa), Fasta scores: E(): 0, 80.4% identity in 358 aa overlap. Also similar to ML1730 and ML2053 from M. leprae. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains PS00190 Cytochrome c family heme-binding site signature. Contains PS00059 Zinc-containing alcohol dehydrogenases signature. Note previously known as adhE2. ;UniProt_AC=Q9CBN2;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2094331	2096412	.	-	0	Locus=ML1734c;Name=nrdE;Function=INVOLVED IN THE DNA REPLICATION PATHWAY. CATALYZES THE BIOSYNTHESIS OF DEOXYRIBONUCLEOTIDES FROM THE CORRESPONDING RIBONUCLEOTIDES, PRECURSORS THAT ARE NECESSARY FOR DNA SYNTHESIS. [CATALYTIC ACTIVITY: 2'-DEOXYRIBONUCLEOSIDE DIPHOSPHATE + OXIDIZED THIOREDOXIN + H(2)O = RIBONUCLEOSIDE DIPHOSPHATE + REDUCED THIOREDOXIN].;Product=RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN);Comments=ML1734c, len: 693 aa. Probable nrdE, ribonucleoside diphosphate reductase [alpha] chain (EC 1.17.4.1). Highly similar to Mycobacterium tuberculosis ribonucleoside-diphosphate reductase alpha chain (EC 1.17.4.1) Rv3051c SW:RIR1_MYCTU (P50640) (693 aa), Fasta scores: E(): 0, 93.2% identity in 693 aa overlap. Contains Pfam match to entry PF00317 ribonucleo_red, Ribonucleotide reductase. Contains PS00089 Ribonucleotide reductase large subunit signature.;UniProt_AC=Q9CBQ0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2790919	2792190	.	-	0	Locus=ML2349c;Name=papA5;Function=;Product=POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA5;Comments=ML2349c, len: 423 aa. Possible papA5, conserved polyketide synthase (PKS) associated protein (see Camacho et al., 2001). Similar to Mycobacterium tuberculosis Rv2939 TR:P96208 (EMBL:Z83857) papA5, conserved polyketide synthase (PKS) associated protein (422 aa), fasta scores: E(): 0, 83.8% identity in 426 aa and Mycobacterium bovis SW:YMA3_MYCBO (Q02279) (354 aa) fasta scores: E(): 0, 81.6% identity in 347 aa.;UniProt_AC=Q49939;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2630076	2631407	.	-	0	Locus=ML2213c;Name=pepC;Function=;Product=PROBABLE AMINOPEPTIDASE PEPC;Comments=ML2213c, len: 443 aa. Probable pepC, aminopeptidase I (EC 3.4.11.-). Similar to Mycobacterium tuberculosis aminopeptidase Rv0800 OR MTCY07H7A.09C TR:O06634 (EMBL:Z95618) fasta scores: E(): 0, 78.3% identity in 433 aa, and to Saccharomyces cerevisiae vacuolar aminopeptidase I precursor ApE1 SW:AMPL_YEAST (P14904; P22060) fasta scores: E(): 5.7e-22, 31.5% identity in 454 aa. Contains Pfam match to entry PF02127 Peptidase_M18, Aminopeptidase I zinc metalloprotease (M18).;UniProt_AC=Q50022;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2961008	2961547	.	-	0	Locus=ML2487c;Name=pyrE;Function=;Product=PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE);Comments=ML2487c, len: 179 aa. Probable pyrE, purine/pyrimidine phosphoribosyltransferase (EC 2.4.2.10). Similar to Mycobacterium tuberculosis  purine/pyrimidine phosphoribosyltransferase Rv0382c or MTV036.17c TR:O53717 (EMBL:AL021931) fasta scores: E(): 0, 86.2% identity in 174 aa, and to Pyrococcus abyssi orotate phosphoribosyltransferase pyre or pab2430 SW:PYRE_PYRAB (P56814) fasta scores: E(): 7.6e-16, 37.1% identity in 175 aa. Contains Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain. Contains PS00589 PTS HPR component serine phosphorylation site signature.;UniProt_AC=Q9CB28;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2732194	2734605	.	+	0	Locus=ML2308;Name=ponA2;Function=INVOLVED IN PEPTIDOGLYCAN SYNTHESIS (AT THE FINAL STAGES), CELL WALL FORMATION. SYNTHESIS OF CROSS-LINKED PEPTIDOGLYCAN FROM THE LIPID INTERMEDIATES. THE ENZYME HAS A PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE N-TERMINAL DOMAIN (FORMATION OF LINEAR GLYCAN STRANDS) AND A PENICILLIN-SENSITIVE TRANSPEPTIDASE C-TERMINAL DOMAIN (CROSS-LINKING OF THE PEPTIDE SUBUNITS). SUPPOSED INVOLVED IN STATIONARY-PHASE SURVIVAL.;Product=PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE (PEPTIDOGLYCAN TGASE) + PENICILLIN-SENSITIVE TRANSPEPTIDASE (DD-TRANSPEPTIDASE)];Comments=ML2308, len: 803 aa. Probable ponA2, penicillin-binding protein (class A), bienzymatic membrane-associated protein with transglycosylase (EC 2.4.2.-) and transpeptidase (EC 3.4.-.-) activities. Previously characterised Mycobacterium leprae penicillin-binding protein Pon1 TR:P72351 (EMBL:S82044) (821 aa) fasta scores: E(): 0, 98.6% identity in 783 aa. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain. Contains Pfam match to entry PF00912 Transglycosyl, Transglycosylase. NOte previously known as pon1.;UniProt_AC=Q9CB85;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2620622	2622292	.	-	0	Locus=ML2206c;Name=purF;Function=;Product=AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE);Comments=ML2206c, len: 556 aa. Probable purF, amidophosphoribosyltransferase (EC 2.4.2.14). Similar to Mycobacterium tuberculosis amidophosphoribosyltransferase precursor Rv0808 SW:PUR1_MYCTU (O06626) fasta scores: E(): 0, 91.3% identity in 518 aa, and to Bacillus subtilis amidophosphoribosyltransferase precursor PURF SW:PUR1_BACSU (P00497) fasta scores: E(): 0, 45.1% identity in 470 aa. Contains 2 Pfam matches to entry PF00310 GATase_2, Glutamine amidotransferases class-II. Contains Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain. Contains PS00103 Purine/pyrimidine phosphoribosyl transferases signature.;UniProt_AC=Q50028;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2014730	2016961	.	-	0	Locus=ML1671c;Name=recG;Function=CRITICAL ROLE IN RECOMBINATION AND DNA REPAIR. HELP PROCESS HOLLIDAY JUNCTION INTERMEDIATES TO MATURE PRODUCTS BY CATALYSING BRANCH MIGRATION. HAS A DNA UNWINDING ACTIVITY CHARACTERISTIC OF A DNA HELICASE WITH A 3' TO 5' POLARITY. RECG UNWIND BRANCHED DUPLEX DNA (Y-DNA).;Product=PROBABLE ATP-DEPENDENT DNA HELICASE RECG;Comments=ML1671c, len: 743 aa. Probable recG, ATP-dependent DNA helicase (EC 3.6.1.-). Highly similar to many ATP-dependent DNA helicases including: Staphylococcus aureus SW:RECG_STAAU (O50581) (686 aa), Fasta scores: E(): 2e-24, 35.7% identity in 701 aa overlap and Mycobacterium tuberculosis Rv2973c SW:RECG_MYCTU (P95122) (737 aa), Fasta scores: E(): 0, 79.4% identity in 744 aa overlap. Contains Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O69460;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2255797	2256987	.	-	0	Locus=ML1877c;Name=tuf;Function=;Product=PROBABLE IRON-REGULATED ELONGATION FACTOR TU TUF (EF-TU);Comments=ML1877c, len: 396 aa. Probable tuf, iron-regulated elongation factor EF-Tu. Similar to M. tuberculosis elongation factor TU Rv0685 SW:EFTU_MYCTU (P31501) (396 aa), Fasta scores: E(): 0, 94.9% identity in 396 aa overlap, and to many others e.g. Escherichia coli SW:EFTU_ECOLI (P02990) (393 aa), Fasta scores: E(): 0, 74.9% identity in 395 aa overlap. Also similar to ML1498, ML1556, ML0611 and ML1878 from M. leprae. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family. Contains PS00301 GTP-binding elongation factors signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=P30768;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	2326360	2327646	.	+	0	Locus=ML1940;Name=xseA;Function=BIDIRECTIONALLY DEGRADES SINGLE-STRANDED DNA INTO LARGE ACID-INSOLUBLE OLIGONUCLEOTIDES, WHICH ARE THEN DEGRADED FURTHER INTO SMALL ACID-SOLUBLE OLIGONUCLEOTIDES [CATALYTIC ACTIVITY: EXONUCLEOLYTIC CLEAVAGE IN EITHER 5'- TO 3'- OR 3'- TO 5'-DIRECTION TO YIELD 5'-PHOSPHOMONONUCLEOTIDES] ;Product=PROBABLE EXODEOXYRIBONUCLEASE VII (LARGE SUBUNIT) XSEA (EXONUCLEASE VII LARGE SUBUNIT);Comments=ML1940, len: 428 aa. Probable xseA, exonuclease VII large subunit (EC 3.1.11.6). Similar to M. tuberculosis exonuclease VII large subunit xseA Rv1108c, and to many others e.g. Escherichia coli exodeoxyribonuclease large subunit SW:EX7L_ECOLI (P04994) (456 aa), Fasta scores: E(): 1.7e-28, 31.8% identity in 425 aa overlap.;UniProt_AC=Q9X783;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	3033668	3035314	.	-	0	Locus=ML2546c;Name=fadD2;Function=;Product=PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE);Comments=ML2546c, len: 548 aa. Probable fadD2, acyl-CoA ligase (EC 6.2.1.-). Similar to Rhizobium trifolii malonyl CoA synthetase MATB TR:Q9ZIP5 (EMBL:AF117694) fasta scores: E(): 2.4e-31, 31.2% identity in 507 aa and Mycobacterium tuberculosis hypothetical 59.9 kda protein Rv0270 TR:P95227 (EMBL:Z86089) fasta scores: E(): 0, 82.3% id in 558 aa. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature.;UniProt_AC=Q9CD27;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2962283	2963143	.	-	0	Locus=ML2489c;Name=ML2489c;Function=;Product=POSSIBLE CONSERVED SECRETED PROTEIN;Comments=ML2489c, len: 286 aa. Possible conserved secreted protein. Similar to Mycobacterium tuberculosis hypothetical secreted protein Rv0383c or MTV036.18c TR:O53718 (EMBL:AL021931) fasta scores: E(): 0, 82.2% identity in 286 aa. Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CB27;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2893807	2894796	.	-	0	Locus=ML2419c;Name=hemB;Function=;Product=PROBABLE DELTA-AMINOLEVULINIC ACID DEHYDRATASE HEMB (PORPHOBILINOGEN SYNTHASE) (ALAD) (ALADH);Comments=ML2419c, len: 329 aa. Probable hemB, delta-aminolevulinic acid dehydratase (EC 4.2.1.24). Similar to many including: Mycobacterium tuberculosis delta-aminolevulinic acid dehydratase Rv0512 SW:HEM2_MYCTU (O33357) (329 aa) fasta scores: E(): 0, 87.5% identity in 329 aa, and to Escherichia coli delta-aminolevulinic acid dehydratase HemB SW:HEM2_ECOLI (P15002; P78247) (323 aa) fasta scores: E(): 0, 46.7% identity in 317 aa. Contains Pfam match to entry PF00490 ALAD, Delta-aminolevulinic acid dehydratase. Contains PS00169 Delta-aminolevulinic acid dehydratase active site.;UniProt_AC=P46723;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2894843	2896534	.	-	0	Locus=ML2420c;Name=hemD;Function=;Product=PROBABLE UROPORPHYRIN-III C-METHYLTRANSFERASE HEMD (UROPORPHYRINOGEN III METHYLASE) (UROGEN III METHYLASE) (SUMT) (UROGEN III METHYLASE) (UROM);Comments=ML2420c, len: 563 aa. Probable hemD, uroporphyrin-III C-methyltransferase (EC 2.1.1.107). Similar to Mycobacterium tuberculosis Rv0511 TR:P95077 (EMBL:Z83865) (565 aa) fasta scores: E(): 0, 85.7% identity in 565 aa and to Clostridium josui porphyrin biosynthesis protein HemD [includes: uroporphyrin-III C-methyltransferase hemD SW:HEM4_CLOJO (Q59294) (504 aa) fasta scores: E(): 3e-24, 24.4% identity in 545 aa. Contains Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases.;UniProt_AC=Q9CB60;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2905498	2906382	.	-	0	Locus=ML2430c;Name=proC;Function=;Product=PROBABLE PYRROLINE-5-CARBOXYLATE REDUCTASE PROC (P5CR) (P5C REDUCTASE);Comments=ML2430c, len: 294 aa. Probable proC, pyrroline-5-carboxylate reductase (EC 1.5.1.2). Similar to Mycobacterium tuberculosis pyrroline-5-carboxylate reductase Rv0500 SW:PROC_MYCTU (Q11141) (295 aa) fasta scores: E(): 0, 82.4% identity in 295 aa, and to Escherichia coli pyrroline-5-carboxylate reductase SW:PROC_ECOLI (P00373) (269 aa) fasta scores: E(): 1.2e-17, 34.0% identity in 285 aa. Contains Pfam match to entry PF01089 P5CR, Delta 1-pyrroline-5-carboxylate reductase. Contains PS00521 Delta 1-pyrroline-5-carboxylate reductase signature.;UniProt_AC=P46725;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2918008	2919294	.	-	0	Locus=ML2443c;Name=mshA;Function=;Product=GLYCOSYLTRANSFERASE MSHA;Comments=ML2443c, len: 428 aa. Probable mshA, glycosyltransferase (EC 2.4.1.-). Similar to many proteins on undefined function and possible transferases including: Mycobacterium tuberculosis glycosyltransferase Rv0486 SW:Y486_MYCTU (Q11152) (480 aa) fasta scores: E(): 0, 86.6% identity in 432 aa, and to Streptomyces coelicolor putative transferase TR:Q9Z5B7 (EMBL:AL035478) (406 aa) fasta scores: E(): 1.7e-30, 34.2% identity in 401 aa. Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1.;UniProt_AC=P54138;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3085096	3086280	.	-	0	Locus=ML2583c;Name=ML2583c;Function=;Product=Possible glycosyl transferase;Comments=ML2583c, len: 394 aa. Possible glycosyl transferase. Similar to Mycobacterium tuberculosis hypothetical protein Rv0225 TR:P96407 (EMBL:Z92669) fasta scores: E(): 0, 84.9% identity in 383 aa and to Methanobacterium thermoautotrophicum LPS biosynthesis related protein TR:O26275 (EMBL:AE000805) fasta scores: E(): 9.9e-21, 29.3% identity in 375 aa. Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1.;UniProt_AC=O69493;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2966123	2967706	.	+	0	Locus=ML2491;Name=ML2491;Function=;Product=CONSERVED HYPOTHETICAL PROTEIN;Comments=ML2491, len: 527 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv1754c TR:O06790 (EMBL:Z95890) (563 aa) fasta scores: E(): 5.9e-92, 61.49% identity in 548 aa, and to Mycobacterium smegmatis hypothetical 35.9 kda protein in asd 3'region SW:YASD_MYCSM (P41402) fasta scores: E(): 0.0048, 25.0% identity in 348 aa. Note start changed since original submission.;UniProt_AC=Q9CB25;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	2984308	2985174	.	-	0	Locus=ML2503c;Name=rmlA;Function=;Product=ALPHA-D-GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE RMLA (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE);Comments=ML2503c, len: 288 aa. Probable rmlA, glucose-1-phosphate thymidyltransferase (EC 2.7.7.24). Similar to Mycobacterium tuberculosis glucose-1-phosphate thymidylyltransferase Rv0334 TR:P72017 (EMBL:U55242) fasta scores: E(): 0, 86.9% id in 282 aa, and to Escherichia coli glucose-1-phosphate thymidylyltransferase RfbA SW:RBA2_ECOLI (P55253) fasta scores: E(): 0, 61.1% identity in 283 aa. Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase.;UniProt_AC=Q9CB18;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3037546	3038214	.	+	0	Locus=ML2549;Name=ML2549;Function=;Product=conserved hypothetical protein;Comments=ML2549, len: 222 aa. Conserved hypothetical protein. Similar to several proteins of undefined function including: Mycobacterium tuberculosis hypothetical protein Rv0264c TR:P95221 (EMBL:Z86089) fasta scores: E(): 0, 75.2% identity in 202 aa, and to Escherichia coli hypothetical protein SW:YBGJ_ECOLI (P75744) fasta scores: E(): 9.5e-20, 40.1% identity in 182 aa.;UniProt_AC=Q9CD26;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3055237	3057072	.	+	0	Locus=ML2563;Name=fadE5;Function=;Product=PROBABLE ACYL-CoA DEHYDROGENASE FADE5;Comments=ML2563, len: 611 aa. Probable fadE5, acyl-CoA dehydrogenase (EC 1.3.99.-).  Similar to Mycobacterium tuberculosis putative acyl-CoA dehydrogenase Rv0244c TR:O53666 (EMBL:AL021929) fasta scores: E(): 0, 89.4% identity in 611 aa. Contains 2 Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase.;UniProt_AC=O69506;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	3080183	3081337	.	-	0	Locus=ML2580c;Name=ML2580c;Function=;Product=PROBABLE INTEGRAL MEMBRANE ACYLTRANSFERASE;Comments=ML2580c, len: 384 aa. Probable integral membrane acyltransferase (EC 2.3.1.-). Similar to Mycobacterium tuberculosis integral membrane acyltransferase Rv0228 TR:P96410 (EMBL:Z92669) fasta scores: E(): 0, 79.5% identity in 381 aa, and to Streptomyces mycarofaciens acyltransferase involved in midecamycin biosynthesis SW:MDMB_STRMY (Q00718) fasta scores: E(): 1.3e-13, 28.8% identity in 400 aa. Also similar to ML1101 from M. leprae.;UniProt_AC=O69496;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3082931	3084733	.	+	0	Locus=ML2582;Name=ML2582;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2582, len: 600 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 59.1 kda protein Rv0226c OR MTCY08D5.21C TR:P96408 (EMBL:Z92669) fasta scores: E(): 0, 70.1% identity in 581 aa. Contains a possible N-terminal signal sequence and multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CD17;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3094813	3096372	.	+	0	Locus=ML2591;Name=mce1C;Function=;Product=MCE-FAMILY PROTEIN MCE1C;Comments=ML2591, len: 519 aa. mce1C, Mce-family protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0171 TR:O07415 (EMBL:Z97050) fasta scores: E(): 0, 72.4% identity in 525 aa. Orthologue of M. tuberculosis Mce1C (Rv0171). Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CD12;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	3099133	3100683	.	+	0	Locus=ML2594;Name=mce1F;Function=;Product=MCE-FAMILY PROTEIN MCE1F;Comments=ML2594, len: 516 aa. mce1F, Mce-family protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0174 TR:O07418 (EMBL:Z97050) fasta scores: E(): 0, 76.5% identity in 515 aa. Orthologue of M. tuberculosis Mce1F (Rv0174). Contains a possible N-terminal signal sequence.;UniProt_AC=Q9CD09;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	3072692	3074065	.	+	0	Locus=ML2573;Name=gabD;Function=;Product=PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD;Comments=ML2573, len: 457 aa. Probable gabD, succinate-semialdehyde dehydrogenase (EC 1.2.1.16). Similar to Mycobacterium tuberculosis GabD1 OR Rv0234c TR:P96417 (EMBL:Z92669) fasta scores: E(): 0, 82.9% identity in 479 aa, and to Escherichia coli succinate-semialdehyde dehydrogenase [NADP+] GabD SW:GABD_ECOLI (P25526) fasta scores: E(): 0, 35.4% identity in 460 aa. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase family. Contains PS00070 Aldehyde dehydrogenases cysteine active site.;UniProt_AC=O69497;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2963228	2965774	.	-	0	Locus=ML2490c;Name=clpB;Function=;Product=PROBABLE ENDOPEPTIDASE ATP BINDING PROTEIN (CHAIN B) CLPB (CLPB PROTEIN) (HEAT SHOCK PROTEIN F84.1);Comments=ML2490c, len: 848 aa. Probable clpB, endopeptidase ATP binnding protein. Similar to Mycobacterium tuberculosis ClpB protein Rv0384c SW:CLPB_MYCTU (O53719) fasta scores: E(): 0, 89.0% identity in 848 aa, and to Escherichia coli protein ClpB TR:BAA16476 (EMBL:D90887) fasta scores: E(): 0, 54.8% id in 847 aa. Also similar to ML0235 from M. leprae. Contains Pfam match to entry PF00495 clpA_B, Chaperonin clpA/B. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00870 Chaperonins clpA/B signature 1. Contains PS00871 Chaperonins clpA/B signature 2.;UniProt_AC=Q9CB26;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	2926564	2927244	.	-	0	Locus=ML2451c;Name=deoC;Function=;Product=PROBABLE DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOC (PHOSPHODEOXYRIBOALDOLASE) (DEOXYRIBOALDOLASE);Comments=ML2451c, len: 226 aa. Probable deoC, deoxyribose-phosphate aldolase (EC 4.1.2.4). Similar to Mycobacterium tuberculosis deoxyribose-phosphate aldolase Rv0478 SW:DEOC_MYCTU (Q11138) fasta scores: E(): 0, 78.6% identity in 224 aa, and to Bacillus subtilis deoxyribose-phosphate aldolase DeoC SW:DEOC_BACSU (P39121) fasta scores: E(): 9.9e-24, 44.7% identity in 206 aa. Contains Pfam match to entry PF01791 DeoC, Deoxyribose-phosphate aldolase.;UniProt_AC=Q9CB45;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3230323	3232137	.	-	0	Locus=ML2680c;Name=dnaB;Function=;Product=PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase;Comments=ML2680c, len: 604 aa. Probable dnaB, replicative DNA helicase(EC 3.6.1.-). Similar to Mycobacterium tuberculosis replicative DNA helicase Rv0058 SW:DNAB_MYCTU (P71715) fasta scores: E(): 0, 66.6% in 554 aa, and to Escherichia coli replicative DNA helicase SW:DNAB_ECOLI (P03005) fasta scores: E(): 5.3e-31, 29.6% in 585 aa. Note the M. leprae DnaB orthologue contains an intein (approximately between residues 274..418). Contains a probable helix-turn-helix motif at aa 505-526 (Score 1068, SD +2.82) Contains Pfam match to entry PF00772 DnaB, DnaB-like helicase. Belongs to the helicase family. DnaB subfamily. ;UniProt_AC=P46394;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	3058972	3060336	.	+	0	Locus=ML2565;Name=fabG4;Function=;Product=PROBABLE 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG4 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE);Comments=ML2565, len: 454 aa. Probable fabG4, 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100). Highly similar to Mycobacterium tuberculosis fabG4, 3-oxoacyl-[acyl-carrier protein] reductase Rv0242c TR:O53665 (EMBL:AL021929) fasta scores: E(): 0, 84.8% id in 454 aa. The C-terminal portion of the predicted product of this CDS is similar to many 3-oxoacyl-[acyl-carrier protein] reductases e.g. Vibrio harveyi FabG SW:FABG_VIBHA (P55336) fasta scores: E(): 4.5e-27, 41.1% identity in 241 aa.  Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature.;UniProt_AC=O69504;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2897502	2898905	.	-	0	Locus=ML2422c;Name=hemA;Function=;Product=PROBABLE GLUTAMYL-TRNA REDUCTASE HEMA (GLUTR);Comments=ML2422c, len: 467 aa. Probable hemA, glutamyl-tRNA reductase (EC 1.2.1.-). Similar to Mycobacterium tuberculosis glutamyl-tRNA reductase Rv0509 SW:HEM1_MYCTU (Q11139) (468 aa) fasta scores: E(): 0, 82.3% identity in 463 aa, and to Bacillus subtilis glutamyl-tRNA reductase SW:HEM1_BACSU (P16618) (455 aa) fasta scores: E(): 0, 30.3% identity in 458 aa. Contains Pfam match to entry PF00745 GlutR, Glutaminyl-tRNA reductase. Contains PS00747 Glutamyl-tRNA reductase signature.;UniProt_AC=P46724;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2940912	2941700	.	+	0	Locus=ML2467;Name=ML2467;Function=CATALYZES THE FIRST COMMITTED STEP IN THE SYNTHESIS OF DECAPRENYL DIPHOSPHATE, A MOLECULE WHICH HAS A CENTRAL ROLE IN THE BIOSYNTHESIS OF MOST FEATURES OF THE MYCOBACTERIAL CELL WALL. ADDS ONE ISOPRENE UNIT TO OMEGA,E-GERANYL DIPHOSPHATE. THE PRODUCT, OMEGA,E, Z-FARNESYL DIPHOSPHATE, IS THE PUTATIVE SUBSTRATE OF Rv2361c PRODUCT [CATALYTIC ACTIVITY: Geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate].;Product=SHORT (C15) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE (Z-FPP SYNTHASE) (Z-FARNESYL DIPHOSPHATE SYNTHASE) (Z-FPP SYNTHETASE) (Z-FARNESYL DIPHOSPHATE SYNTHETASE) (GERANYLTRANSTRANSFERASE) (FARNESYL PYROPHOSPHATE SYNTHETASE);Comments=ML2467, len: 262 aa. Possible short chain Z-isoprenyl diphosphate synthetase (EC 2.5.1.10). Similar to Mycobacterium tuberculosis short chain Z-isoprenyl diphosphate synthetase Rv1086 SW:YA86_MYCTU (O53434) fasta scores: E(): 0, 90.5% identity in 262 aa and to Synechocystis sp. undecaprenyl pyrophosphate synthetase SW:UPPS_SYNY3 (Q55482) fasta scores: E(): 5.2e-29, 40.2% identity in 239 aa. Contains Pfam match to entry PF01255 UPP_synthetase, Putative undecaprenyl diphosphate synthase. Contains PS01066 Undecaprenyl pyrophosphate synthetase family signature.;UniProt_AC=Q9CB36;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	2980189	2982831	.	+	0	Locus=ML2501;Name=ML2501;Function=;Product=PROBABLE IRON-SULFUR-BINDING REDUCTASE;Comments=ML2501, len: 880 aa. Probable iron-sulphur-binding reductase. Similar to Mycobacterium tuberculosis hypothetical protein Rv0338c  TR:O33268 (EMBL:Z97991) fasta scores: E(): 0, 78.1% identity in 894 aa, and to Streptomyces coelicolor putative iron-sulphur-binding reductase SCH35.51C TR:Q9X8V5 (EMBL:AL078610) fasta scores: E(): 0, 48.2% id in 776 aa. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00037 fer4, 4Fe-4S binding domain. Contains PS00070 Aldehyde dehydrogenases cysteine active site. Contains 2 x PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.;UniProt_AC=Q9CB20;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3185869	3187515	.	-	0	Locus=ML2661c;Name=fadD7;Function=;Product=PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE);Comments=ML2661c, len: 548 aa. Probable fadD7, fatty-acid-CoA synthase (EC 6.2.1.-).  Similar to many Prokaryotic and Eukaryotic acyl-CoA synthases including: Mycobacterium tuberculosis fadD7 protein Rv0119 TR:O07169 (EMBL:Z96071) fasta scores: E(): 0, 71.3% in 520 aa, and to Saccharomyces cerevisiae peroxisomal-coenzyme a synthetase SW:FAT2_YEAST (P38137) fasta scores: E(): 0, 35.6% in 526 aa. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature.;UniProt_AC=Q9CCY8;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	3065565	3069782	.	+	0	Locus=ML2570;Name=ML2570;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2570, len: 1405 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0236c TR:P96419 (EMBL:Z92669) fasta scores: E(): 0, 78.7% identity in 1397 aa. Contains a possible N-terminal signal sequence and multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CD19;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3264173	3264919	.	-	0	Locus=ML2708c;Name=gidB;Function=;Product=PROBABLE GLUCOSE-INHIBITED DIVISION PROTEIN B GIDB (Methyltransferase);Comments=ML2708c, len: 248 aa. Probable gidB, Glucose inhibited division protein B (EC 2.1.-.-). Similar to Mycobacterium paratuberculosis putative glucose inhibited division protein B TR:AAF33688 (EMBL:AF222789) fasta scores: E(): 0, 64.2% in 243 aa, and to Mycobacterium tuberculosis glucose inhibited division protein B SW:GIDB_MYCTU (O53597) fasta scores: E(): 0, 68.4% in 212 aa. Belongs to the gidB family.;UniProt_AC=Q50203;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3194558	3196414	.	-	0	Locus=ML2667c;Name=ML2667c;Function=;Product=possible membrane transport protein;Comments=ML2667c, len: 618 aa. Possible membrane transport protein. Similar to several manganese transport proteins e.g. Pseudomonas aeruginosa manganese transport protein MntH1 SW:MNT1_PSEAE (Q9RPF3) fasta scores: E(): 6.5e-13, 27.4% in 420 aa, and to Deinococcus radiodurans probable manganese transport protein MntH SW:MNTH_DEIRA (Q9RTP8) fasta scores: E(): 4e-15, 27.2% in 419 aa. Also similar to Q8VP26 Natural resistance-associated macrophage protein from Burkholderia cenocepacia (548 aa), fasta scores: E(): 8.3e-90, (48.700% identity in 577 aa overlap). Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CCY6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3197970	3199970	.	-	0	Locus=ML2670c;Name=ML2670c;Function=;Product=POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE;Comments=ML2670c, len: 666 aa. Possible transmembrane acyltransferase (EC 2.3.1.-). Similar to Mycobacterium tuberculosis transmembrane acetyltransferase TR:O53633 (EMBL:AL021926) fasta scores: E(): 0, 78.6% in 681 aa. Also similar to Salmonella typhimurium OafA, a member of the integral membrane trans-acylases TR:P74874 (EMBL:U65941) fasta scores: E(): 7.9e-16, 25.2% in 658 aa. Contains multiple possible membrane spanning hydrophobic domains. Contains 2 Pfam matches to entry PF01757 DUF33, Domain of unknown function.;UniProt_AC=Q9CCY5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3225410	3228091	.	+	0	Locus=ML2679;Name=ML2679;Function=;Product=Conserved hypothetical protein;Comments=ML2679, len: 893 aa. Conserved hypothetical protein. Similar in parts to many proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical 95.4 kda protein Rv2567 SW:YP67_MYCTU (Q50654; Q50731) fasta scores: E(): 0, 75.2% in 883 aa. Similar to ML0605 and ML0507 (psuedogene).;UniProt_AC=O53121;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	3248277	3249737	.	-	0	Locus=ML2697c;Name=pcnA;Function=;Product=PROBABLE POLY(A) POLYMERASE PCNA (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) (NTP POLYMERASE) (RNA ADENYLATING ENZYME) (POLY(A) POLYMERASE);Comments=ML2697c, len: 486 aa. Probable pcnA, polynucleotide polymerase (EC 2.7.7.19). Similar to several polynucleotide polymerases (EC 2.7.7.19) including Mycobacterium tuberculosis TR:O05438 (EMBL:Z94121) fasta scores: E(): 0, 83.9% in 478 aa, and Bacillus subtilis poly SW:PAPS_BACSU (P42977) fasta scores: E(): 1.4e-24, 30.3% in 456 aa. Contains Pfam match to entry PF01966 HD, HD domain. Contains Pfam match to entry PF01743 PolyA_pol, Poly A polymerase family. Contains PS00018 EF-hand calcium-binding domain.;UniProt_AC=Q9CCY1;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1853565	1854770	.	-	0	Locus=ML1537c;Name=eccE5;Function=;Product=ESX CONSERVED COMPONENT ECCE5. PROBABLE MEMBRANE PROTEIN.;Comments=ML1537c, len: 401 aa. Conserved membrane protein. Highly similar to a protein of unknown function from Mycobacterium tuberculosis Rv1797 TR:O53946 (EMBL:AL022021) (406 aa), Fasta scores: E(): 0, 68.5% identity in 406 aa overlap. Contains a possible N-terminal signal sequence and a possible membrane spanning hydrophobic domain. Contains PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.;UniProt_AC=Q9CBV4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3253066	3256686	.	+	0	Locus=ML2700;Name=ML2700;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2700, len: 1206 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 123.6 kda protein Rv3910 TR:O05435 (EMBL:Z94121) fasta scores: E(): 0, 75.1% in 1182 aa. Also the N-terminus is similar to several virulence associated proteins e.g. Salmonella typhimurium virulence factor MviN SW:MVIN_SALTY (P37169) fasta scores: E(): 3e-17, 29.0% in 527 aa. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CCX9;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3259768	3260988	.	+	0	Locus=ML2704;Name=ML2704;Function=;Product=PROBABLE HYDROLASE;Comments=ML2704, len: 406 aa. Probable hydrolase. Similar to Mycobacterium tuberculosis putative hydrolase Rv3915 TR:O53593 (EMBL:AL021426) fasta scores: E(): 0, 86.9% in 406 aa. Contains 2 Pfam matches to entry PF01471 PG_binding_1, Putative peptidoglycan binding domain. Contains Pfam match to entry PF01520 Amidase_3, N-acetylmuramoyl-L-alanine amidase.;UniProt_AC=Q9CCX8;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3262117	3263124	.	-	0	Locus=ML2706c;Name=parB;Function=;Product=PROBABLE CHROMOSOME PARTITIONING PROTEIN PARB;Comments=ML2706c, len: 335 aa. Probable parB, chromosome partitioning protein. Similar to many proteins thought to be involved with chromosome partitioning e.g. Mycobacterium tuberculosis hypothetical 37.0 kda protein Rv3917c TR:O53595 (EMBL:AL021426) fasta scores: E(): 0, 78.6% in 332 aa, and to Streptomyces coelicolor ParB TR:Q9RFM2 (EMBL:AF187159) fasta scores: E(): 0, 50.7% in 347 aa, and to Bacillus subtilis stage 0 sporulation protein J SW:SP0J_BACSU (P26497) fasta scores: E(): 1.7e-28, 42.3% in 272 aa. Contains Pfam match to entry PF02195 ParBc, ParB-like nuclease domain.;UniProt_AC=Q50201;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3265654	3266796	.	-	0	Locus=ML2710c;Name=ML2710c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2710c, len: 380 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis putative membrane protein Rv3921c TR:O53599 (EMBL:AL021426) fasta scores: E(): 0, 77.1% in 380 aa, and to Streptomyces coelicolor inner membrane protein TR:O54569 (EMBL:AF031590) fasta scores: E(): 1.8e-18, 29.0% in 366 aa. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF02096 60KD_IMP, 60Kd inner membrane protein.;UniProt_AC=Q50205;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3267135	3267497	.	-	0	Locus=ML2712c;Name=rnpA;Function=RNaseP CATALYZES THE REMOVAL OF THE 5'-LEADER SEQUENCE FROM PRE-tRNA TO PRODUCE THE MATURE 5'TERMINUS. IT CAN ALSO CLEAVE OTHER RNA SUBSTRATES SUCH AS 4.5S RNA. THE PROTEIN COMPONENT PLAYS AN AUXILIARY BUT ESSENTIAL ROLE IN VIVO BY BINDING TO THE 5'-LEADER SEQUENCE AND BROADENING THE SUBSTRATE SPECIFICITY OF THE RIBOZYME [CATALYTIC ACTIVITY: ENDONUCLEOLYTIC CLEAVAGE OF RNA, REMOVING 5'-EXTRA-NUCLEOTIDE FROM tRNA PRECURSOR].;Product=RIBONUCLEASE P PROTEIN COMPONENT RNPA (RNaseP PROTEIN) (RNase P PROTEIN) (PROTEIN C5);Comments=ML2712c, len: 120 aa. rnpA, ribonuclease P protein component (EC 3.1.26.5). Similar to Mycobacterium tuberculosis ribonuclease P protein component Rv3923c SW:RNPA_MYCTU (Q50789; O53601) fasta scores: E(): 2.9e-26, 63.0% in 119 aa, and to Streptomyces bikiniensis ribonuclease P protein component SW:RNPA_STRBI (P25817) fasta scores: E(): 1.1e-08, 34.8% in 115 aa. Contains Pfam match to entry PF00825 Ribonuclease_P, Ribonuclease P. Contains PS00648 Bacterial ribonuclease P protein component signature.;UniProt_AC=P46610;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	3258259	3259635	.	+	0	Locus=ML2703;Name=trxC;Function=THIOREDOXIN PARTICIPATES IN VARIOUS REDOX REACTIONS THROUGH THE REVERSIBLE OXIDATION OF ITS ACTIVE CENTER DITHIOL, TO A DISULFIDE, & CATALYZES DITHIOL-DISULFIDE EXCHANGE REACTIONS. FORMS TOGETHER WITH THIOREDOXIN REDUCTASE AND NADPH A REDOX ACTIVE SYSTEM WHICH DONATES ELECTRONS TO A WIDE VARIETY OF DIFFERENT METABOLIC PROCESS. SEEMS REGULATED BY SIGH (Rv3223c PRODUCT).;Product=THIOREDOXIN TRXC (TRX) (MPT46);Comments=ML2703, len: 458 aa. Probable trxC, Thioredoxin Previously sequenced and characterised: Mycobacterium leprae bifunctional thioredoxin reductase/thioredoxin [includes: thioredoxin reductase SW:TRXB_MYCLE (P46843) fasta scores: E(): 0, 100.0% in 458 aa. Contains Pfam match to entry PF00085 thiored, Thioredoxin. Contains Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. Contains PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. Contains PS00194 Thioredoxin family active site. Note previously known as trxB.;UniProt_AC=P46843;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3241430	3242539	.	+	0	Locus=ML2692;Name=ML2692;Function=;Product=Probable myo-inositol-1-phosphate synthase Ino1 (Inositol 1-phosphate synthetase) (D-glucose 6-phosphate cycloaldolase) (Glucose 6-phosphate cyclase) (Glucocycloaldolase);Comments=ML2692, len: 369 aa. Probable ino1 (alternate gene name: tbINO), myo-inositol-1-phosphate synthase (EC 5.5.1.4) (see citations below). Identical to ML0396c a possible paralogue of M. tuberculosis ino1. Equivalent to Rv0046c|P71703|AL123456 ino1, myo-inositol-1-phosphate synthase from M. tuberculosis (367 aa), Fasta scores: E(): 0, (91.8% identity in 366 aa overlap). Highly similar to other bacterial myo-inositol-1-phosphate synthase and hypothetical proteins e.g. Q8NLE6 Myo-inositol-1-phosphate synthase from Corynebacterium glutamicum (363 aa), Fasta scores: E(): 0, (73.9% identity in 361 aa overlap); and Q9X8T5|SCH24_21c Hypothetical protein from Streptomyces coelicolor (360 aa).  Contains Pfam match to entry PF01658 Inos-1-P_synth, Myo-inositol-1-phosphate synthase.;UniProt_AC=Q57240;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3210656	3212896	.	-	0	Locus=ML2672c;Name=icd2;Function=;Product=PROBABLE ISOCITRATE DEHYDROGENASE [NADP] ICD2 (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP);Comments=ML2672c, len: 746 aa. Probable icd2, isocitrate dehydrogenase [NADP] (EC 1.1.1.42). Similar to Vibrio sp isocitrate dehydrogenase [NADP] 2 SW:IDH2_VIBA1 (P41561) fasta scores: E(): 0, 59.6% in 741 aa and to Mycobacterium tuberculosis Rv0066c isocitrate dehydrogenase TR:O53611 (EMBL:AL021428) fasta scores: E(): 0, 85.4% in 745 aa.;UniProt_AC=O53115;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	3234977	3236671	.	-	0	Locus=ML2687c;Name=ML2687c;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;Comments=ML2687c, len: 564 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical transmembrane protein cy21d4.14 Rv0051 TR:P71708 (EMBL:Z80775) fasta scores: E(): 0, 78.7% in 531 aa, and to Streptomyces coelicolor hypothetical 44.5 kda protein TR:Q9X7Z2 (EMBL:AL049497) fasta scores: E(): 1.1e-06, 29.6% in 416 aa. Also similar to ML0471 a possible pseudogene similar to M. tuberculosis Rv0051. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=O53127;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3122785	3125826	.	-	0	Locus=ML2617c;Name=mmpL11;Function=;Product=PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL11;Comments=ML2617c, len: 1013 aa. Probable mmpL11, conserved transmembrane transportprotein. Similar to Mycobacterium tuberculosis putative membrane protein Mmpl11 Rv0202c SW:MMLB_MYCTU (O53653) fasta scores: E(): 0, 72.8% identity in 1017 aa, and to Streptomyces coelicolor putative integral membrane protein SC3A4.16C TR:CAB89762 (EMBL:AL354616) fasta scores: E(): 0, 31.8% identity in 761 aa. Also similar to ML2620 from M. leprae. Contains a possible N-terminal signal sequence and multiple other possible membrane spanning hydrophobic domains.;UniProt_AC=O06079;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3061377	3062279	.	+	0	Locus=ML2566;Name=htdX;Function=;Product=conserved hypothetical protein;Comments=ML2566, len: 300 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0241c TR:O53664 (EMBL:AL021929) fasta scores: E(): 0, 81.8% identity in 280 aa, and to Streptomyces coelicolor putative dehydratase TR:CAB77291 (EMBL:AL160312) fasta scores: E(): 2.1e-27, 39.5% identity in 271 aa. Contains Pfam match to entry PF01575 MaoC_dehydratas, MaoC like domain. Contains PS00211 ABC transporters family signature.;UniProt_AC=Q9CD22;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1240281	1240700	.	+	0	Locus=ML1077;Name=rseA;Function=;Product=conserved hypothetical protein;Comments=ML1077, len: 139 aa. Conserved hypothetical protein. Highly similar to anti-sigma factor rseA from Mycobacterium tuberculosis Rv1222 (regulates negatively sigE), Fasta scores: E(): 0, 70.7% identity in 150 aa overlap; and Mycobacterium avium TR:O05736 (EMBL:U87308) (133 aa), Fasta scores: E(): 0, 71.7% identity in 138 aa overlap; and Mycobacterium smegmatis TR:O05768 (EMBL:U87307) (145 aa), Fasta scores: E(): 0, 66.2% identity in 139 aa overlap.;UniProt_AC=Q9CCA5;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	243054	244202	.	+	0	Locus=ML0176;Name=pepD;Function=;Product=Probable serine protease (serine proteinase);Comments=ML0176, len: 382 aa. Probable secreted or membrane serine protease (EC 3.4.21.-), highly similar to Rv0983|O53896|AL123456 probable serine protease from M. tuberculosis (464 aa), Fasta scores: E(): 0, (80.7% identity in 383 aa overlap); and in part to Rv1223|O06291|AL123456 htrA, putative serine protease from M. tuberculosis (549 aa), Fasta scores: E(): 0, (41.8% identity in 347 aa overlap). Similar to many putative serine protease e.g. Q8NS10 trypsin-like serine protease from Corynebacterium glutamicum (413 aa), Fasta scores: E(): 1.3e-35, 47.2% identity in 362 aa overlap. Also similar to ML1078 and ML2659 from M. leprae. Previously sequenced as Q9Z5G6|AL035500 (452 aa), Fasta scores: E(): 0, (100.0% identity in 382 aa overlap). Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF). Contains Pfam match to entry PF00089 trypsin, Trypsin.;UniProt_AC=Q9CD67;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	117870	118778	.	+	0	Locus=ML0095;Name=ubiA;Function=;Product=Possible conserved integral membrane protein;Comments=ML0095, len: 302 aa. Possible conserved integral membrane protein, highly similar to Rv3806c|O53583|AL123456 integral membrane protein from M. tuberculosis (302 aa), Fasta scores: E(): 0, (83.8% identity in 302 aa overlap); and similar to other bacterial putative membrane proteins e.g. CAB89063|AL353872 putative integral membrane protein SC5G8.12 from Streptomyces coelicolor (322 aa), Fasta scores: E(): 0, (48.6% identity in 290 aa overlap); and NOEC_AZOCA|Q43967 possible integral membrane protein found near nod locus from Azorhizobium caulinodans noeC (307 aa), Fasta scores: E(): 1.1e-12, (31.4% identity in 191 aa overlap). Also similar to Q8NLQ9 4-hydroxybenzoate polyprenyltransferases from Corynebacterium glutamicum (332 aa), Fasta scores: E(): 0, (60.8% identity in 293 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CDB5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	50656	51996	.	+	0	Locus=ML0041;Name=mycP1;Function=;Product=Possible secreted protease;Comments=ML0041, len: 446 aa. Possible secreted protease (EC 3.4.21.-), highly similar to Rv3883c|O05461|AL123456 Possible secreted protease from M. tuberculosis (446 aa), Fasta scores: E(): 0, (79.1% identity in 446 aa overlap). Shows weaker similarity to known bacterial proteases e.g. Q46541|L18984 acidic protease V5 from Bacteroides nodosus aprV5 (595 aa), Fasta scores: E(): 1.8e-07, (28.1% identity in 442 aa overlap). Also similar to ML1538 and ML2528 from M. leprae. Previously sequenced as O33076|Y14967 (446 aa), Fasta scores: E(): 0, (99.8% identity in 446 aa overlap). Contains a probable N-terminal signal sequence. Contains 2 Pfam matches to entry PF00082 Peptidase_S8, Subtilase family.;UniProt_AC=O33076;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	68866	70587	.	-	0	Locus=ML0055c;Name=eccA1;Function=;Product=ESX CONSERVED COMPONENT ECCA1;Comments=ML0055c, len: 573 aa. esx conserved component, member of the CBXX/CFQX family of hypothetical proteins; C-terminal end is highly similar to many e.g. SP5K_BACSU|P27643 SpoVK/SpoVJ, stage V sporulation protein from Bacillus subtilis (322 aa), Fasta scores: E(): 3.5e-26, (33.7% identity in 332 aa overlap). Also highly similar to several M. tuberculosis hypothetical proteins e.g. Rv3868|Y2G8_MYCTU|O69733 hypothetical protein of the CBXX/CFQX family from M. tuberculosis (573 aa), Fasta scores: E(): 0, (89.2% identity in 573 aa overlap); and Rv0282. Previously sequenced as Y2G8_MYCLE|O33089 (573 aa), Fasta scores: E(): 0, (100.0% identity in 573 aa overlap). Similar to ML1536 and ML2537 from M. leprae. Shows weak similarity to ML0798. Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA). Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O33089;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3022091	3024013	.	-	0	Locus=ML2537c;Name=eccA3;Function=;Product=ESX CONSERVED COMPONENT ECCA3;Comments=ML2537c, len: 640 aa. esx conserved component, similar to many Mycobacterium tuberculosis hypothetical proteins e.g. Rv0282 |Y282_MYCTU (O53687) fasta scores: E(): 0, 83.6% identity in 628 aa. The C-terminus is also similar to many CBXX/CFQX family proteins e.g. Alcaligenes eutrophus CBXP_ALCEU (Q04540) fasta scores: E(): 3.8e-24, 36.4% identity in 283 aa. Also similar to ML0055 and ML1536 from M. leprae. Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA). Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CD28;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1851736	1853568	.	-	0	Locus=ML1536c;Name=eccA5;Function=;Product=ESX CONSERVED COMPONENT ECCA5;Comments=ML1536c, len: 610 aa. esx conserved component, highly similar to several Mycobacterium tuberculosis proteins of undefined function e.g. Rv1798|YH98_MYCTU (O53947) (610 aa), Fasta scores: E(): 0, 89.7% identity in 609 aa overlap. The C-terminus of this protein is also similar to several including: Bacillus subtilis stage V sporulation protein K SP5K_BACSU (P27643) (322 aa), Fasta scores: E(): 2.2e-20, 34.5% identity in 310 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CBV5;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	67417	68862	.	-	0	Locus=ML0054c;Name=eccB1;Function=;Product=ESX CONSERVED COMPONENT ECCB1. POSSIBLE MEMBRANE PROTEIN.;Comments=ML0054c, len: 481 aa. esx conserved component, possible membrane protein, highly similar to several M. tuberculosis hypothetical proteins e.g. Rv3869|O69734|AL123456 conserved membrane protein (480 aa), Fasta scores: E(): 0, (75.7% identity in 478 aa overlap). Similar to ML1544 and ML2536 from M. leprae. Previously sequenced as O33088|Y14967 (481 aa), Fasta scores: E(): 0, (100.0% identity in 481 aa overlap). Contains hydrophobic, possible membrane-spanning region near the N-terminus.;UniProt_AC=O33088;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3020440	3022098	.	-	0	Locus=ML2536c;Name=eccB3;Function=;Product=ESX CONSERVED COMPONENT ECCB3. POSSIBLE MEMBRANE PROTEIN.;Comments=ML2536c, len: 552 aa. esx conserved component, possible membrane protein. Similar to several Mycobacterium tuberculosis hypothetical proteins e.g. Rv0283 TR:O53688 (EMBL:AL021930) fasta scores: E(): 0, 70.8% identity in 552 aa. Also similar to ML1544 from M. leprae. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9CD29;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1866375	1867895	.	-	0	Locus=ML1544c;Name=eccB5;Function=;Product=ESX CONSERVED COMPONENT ECCB5. POSSIBLE MEMBRANE PROTEIN.;Comments=ML1544c, len: 506 aa. esx conserved component, probable membrane protein. Highly similar to many Mycobacterium tuberculosis proteins of unknown function including:Rv1782 TR:O53933 (EMBL:AL022021) (506 aa), Fasta scores: E(): 0, 82.6% identity in 506 aa overlap. Also similar to ML0054 from M. leprae. Contains a possible membrane spanning hydrophobic domain.;UniProt_AC=Q9Z5I3;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	65186	67420	.	-	0	Locus=ML0053c;Name=eccCa1;Function=;Product=ESX CONSERVED COMPONENT ECCCA1. POSSIBLE TRANSMEMBRANE PROTEIN.;Comments=ML0053c, len: 744 aa. esx conserved component, possible transmembrane protein, highly similar to Rv3870|O69735|AL123456 conserved transmembrane protein from M. tuberculosis (747 aa), Fasta scores: E(): 0, (85.4% identity in 746 aa overlap). Show some similarity with the N-terminal part of several proteins while the downstream ML0052 is similar to the corresponding C-terminal part e.g. O86653|AL031231 putative ATP/GTP-binding proteins from Streptomyces coelicolor (1321 aa), Fasta scores: E(): 0, (34.7% identity in 760 aa overlap); Rv3447c|O06264|AL123456 unknown membrane protein from M. tuberculosis (1236 aa), Fasta scores: E(): 0, (37.2% identity in 732 aa overlap); and Rv1784. Related proteins are also found in Bacillus spp. Similar to the N-terminal halves of ML1543 and ML2535. Contains hydrophobic, possible membrane-spanning region near the N-terminus. Contains Pfam match to entry PF01580 FtsK_SpoIIIE, FtsK/SpoIIIE family. Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=O33087;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	63319	65112	.	-	0	Locus=ML0052c;Name=eccCb1;Function=;Product=ESX CONSERVED COMPONENT ECCCB1;Comments=ML0052c, len: 597 aa. esx conserved component, highly similar to Rv3871|O69736|AL123456 conserved hypothetical protein from M. tuberculosis (591 aa), Fasta scores: E(): 0, (80.9% identity in 596 aa overlap). Show some similarity with the C-terminal part of several proteins while the upstream ML0053 is similar to the corresponding N-terminal part e.g. O86653|AL031231 putative ATP/GTP-binding proteins from Streptomyces coelicolor (1321 aa), Fasta scores: E(): 0, (34.7% identity in 574 aa overlap); Rv3447c|O06264|AL123456 unknown membrane protein from M. tuberculosis (1236 aa), Fasta scores: E(): 0, (35.2% identity in 588 aa overlap); and Rv1784. Related proteins are also found in Bacillus spp. Similar to the C-terminal halves of ML1543 and ML2535. Previously sequenced as O33086|Y14967 (597 aa), Fasta scores: E(): 0, (99.7% identity in 597 aa overlap). Contains 2 Pfam matches to entry PF01580 FtsK_SpoIIIE, FtsK/SpoIIIE family. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CDD7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3016454	3020443	.	-	0	Locus=ML2535c;Name=eccC3;Function=;Product=ESX CONSERVED COMPONENT ECCC3. POSSIBLE MEMBRANE PROTEIN.;Comments=ML2535c, len: 1329 aa. esx conserved component, possible membrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0284 TR:O53689 (EMBL:AL021930) fasta scores: E(): 0, 84.2% identity in 1318 aa and to Streptomyces coelicolor ATP/GTP binding protein SC3C3.20C TR:O86653 (EMBL:AL031231) fasta scores: E(): 0, 36.0% identity in 1379 aa. Also similar in regions to several cell division proteins e.g. Coxiella burnetii cell division protein, FtsK homologue, FTSK_COXBU (P39920) E(): 4.2e-07 28.3% identity in 304. And similar to ML0053 from M. leprae. Contains a possible membrane spanning hydrophobic domain. Contains 2 Pfam matches to entry PF01580 FtsK_SpoIIIE, FtsK/SpoIIIE family. Contains 3 x PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CD30;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1862221	1866378	.	-	0	Locus=ML1543c;Name=eccC5;Function=;Product=ESX CONSERVED COMPONENT ECCC5. PROBABLE MEMBRANE PROTEIN (SpoIIIE FAMILY);Comments=ML1543c, len: 1385 aa. esx conserved component, probable membrane protein (SpoIIIE-family). Highly similar to the C-terminus of Rv1784 hypothetical protein TR:O53935 (EMBL:AL022021) (932 aa), Fasta scores: E(): 0, 87.8% identity in 932 aa overlap. The N-terminus is similar to Rv1783 conserved membrane protein TR:O53934 (EMBL:AL022021) (435 aa), Fasta scores: E(): 0, 87.1% identity in 395 aa overlap. The C-terminus is also similar to several others e.g. Bacillus subtilis SP3E_BACSU (P21458) (787 aa), Fasta scores: E(): 3e-09, 24.0% identity in 391 aa overlap stage III sporulation protein E (SpoIIIE) a protein required for chromosome segregation. Also similar to ML2535 from M. leprae. Contains possible N-terminal membrane spanning hydrophobic domains. Contains 2 Pfam matches to entry PF01580 FtsK_SpoIIIE, FtsK/SpoIIIE family. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9Z5I2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1856526	1858037	.	-	0	Locus=ML1539c;Name=eccD5;Function=;Product=ESX CONSERVED COMPONENT ECCD5. PROBABLE MEMBRANE PROTEIN.;Comments=ML1539c, len: 503 aa. esc conserved component, hypothetical membrane protein. Similar to several Mycobacterium tuberculosis proteins of undefined function e.g. putative membrane protein Rv1795 TR:O53944 (EMBL:AL022021) (503 aa), Fasta scores: 76.9% identity in 503 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CBV2;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	3009264	3010283	.	-	0	Locus=ML2527c;Name=eccE3;Function=;Product=ESX CONSERVED COMPONENT ECCE3. PROBABLE TRANSMEMBRANE PROTEIN.;Comments=ML2527c, len: 339 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0292 TR:O53696 (EMBL:AL021930) fasta scores: E(): 0, 61.6% identity in 333 aa. Contains possible membrane spanning hydrophobic domains.;UniProt_AC=Q9CD37;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1871964	1872647	.	-	0	Locus=ML1547c;Name=pptT;Function=;Product=probable phosphopantetheinyl transferase, by homology with phosphopantetheinyl transferase pptT(Rv2794c) from M. tuberculosis H37Rv;Comments=ML1547c, len: 227 aa. Highly similar to phosphopantetheinyl transferase pptT from Mycobacterium tuberculosis Rv2794c (227 aa), Fasta scores: E(): 0, 79.7% identity in 227 aa overlap. Weakly similar to a number of proteins essential for the production of iron chelators e.g. Escherichia coli enterobactin synthetase component D SW:ENTD_ECOLI (P19925) (209 aa), Fasta scores: E(): 0.002, 29.4% identity in 177 aa overlap. Also similar to Streptomyces sp. L-proline 3-hydroxylase TR:O24813 (EMBL:AB007189) (208 aa), Fasta scores: E(): 0, 50.7% identity in 209 aa overlap;UniProt_AC=Q9Z5I5;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	3118774	3120777	.	-	0	Locus=ML2613c;Name=zmp1;Function=;Product=probable zinc metalloprotease;Comments=ML2613c, len: 667 aa. Probable zinc metalloprotease (EC 3.4.24.-). Similar to Mycobacterium tuberculosis zinc metalloprotease Rv0198c TR:O53649 (EMBL:AL021928) fasta scores: E(): 0, 80.8% identity in 667 aa. Also similar to many Eukaryotic metalloproteases denoted endothelin-converting enzymes e.g. Homo sapiens ECE1 SW:ECE1_HUMAN (P42892) fasta scores: E(): 0, 32.6% identity in 685 aa. Contains Pfam match to entry PF01431 Peptidase_M13, Peptidase family M13. Contains PS00142 Neutral zinc metallopeptidases.;UniProt_AC=O06075;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	297941	298516	.	+	0	Locus=ML0226;Name=folK;Function=;Product=Probable2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase FolK (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK) (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase) (7,8-dihydro-6-hydroxymethylpterin-diphosphokinase) (6-hydroxymethyl-7,8-dihydropterin diphosphokinase);Comments=ML0226, len: 191 aa. Probable folK, 2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase (EC 2.7.6.3), highly similar to Rv3606c|HPPK_MYCTU|O06276 folK, 2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase from M. tuberculosis (188 aa), Fasta scores: E(): 0, (63.2% identity in 190 aa overlap). Similar to many others e.g. to the C-terminal half of SULD_STRPN|P22291 sulD, bifunctional folate synthesis protein (includes: dihydroneopterin aldolase and 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase) from Streptococcus pneumoniae (270 aa), Fasta scores: E(): 1.8e-07, (37.8% identity in 135 aa overlap). Previously sequenced as HPPK_MYCLE|O69528 (191 aa), Fasta scores: E(): 0, (100.0% identity in 191 aa overlap). Contains Pfam match to entry PF01288 HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Contains PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. Belongs to the HPPK family.;UniProt_AC=O69528;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	648423	649550	.	+	0	Locus=ML0535;Name=carA;Function=;Product=Probable carbamoyl-phosphate synthase small chain CarA (Carbamoyl- phosphate synthetase glutamine chain). SUBUNIT: COMPOSED OF TWO CHAINS; THE SMALL (OR GLUTAMINE) CHAIN PROMOTES THE HYDROLYSIS OF GLUTAMINE TO AMMONIA, WHICH IS USED BY THE LARGE (OR AMMONIA) CHAIN TO SYNTHESIZE CARBAMOYL PHOSPHATE. Belongs to the CarA family.;Comments=ML0535, len: 375 aa. Probable carA, Carbamoyl-phosphate synthase small chain (EC 6.3.5.5), highly similar to P71811|AL123456|Rv1383 carA, carbamoyl-phosphate synthase subunit from M. tuberculosis (376 aa), Fasta scores: E(): 0, (85.4% identity in 377 aa overlap); and CAD94279|Mb1418 from M. bovis (376 aa). Similar to many e.g. CARA_ECOLI|P00907 carA, carbamoyl-phosphate synthase subunit from Escherichia coli (382 aa), Fasta scores: E(): 0, (43.2% identity in 389 aa overlap). Contains Pfam match to entry PF00988 CPSase_sm_chain, Carbamoyl-phosphate synthase small chain, CPSase domain. Contains Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I. Contains PS00442 Glutamine amidotransferases class-I active site.;UniProt_AC=Q9CCR3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1484292	1486031	.	+	0	Locus=ML1245;Name=plsC;Function=C-TERMINUS: INVOLVED IN PHOSPHOLIPID BIOSYNTHESIS (AT THE SECOND STEP); CONVERTS LYSOPHOSPHATIDIC ACID (LPA) INTO PHOSPHATIDIC ACID BY INCORPORATING ACYL MOIETY AT THE 2 POSITION [CATALYTIC ACTIVITY 2: ACYL-CoA + 1-ACYL-SN-GLYCEROL 3-PHOSPHATE = CoA + 1,2-DIACYL-SN-GLYCEROL 3-PHOSPHATE]. N-TERMINUS: COULD BE GENERATE SERINE AND PHOSPHATE FROM PHOSPHOSERINE; MAY CATALYZE THE LAST STEP IN THE BIOSYNTHESIS OF SERINE FROM CARBOHYDRATES (THE REACTION MECHANISM COULD BE PROCEED VIA THE FORMATION OF A PHOSPHORYL-ENZYME INTERMEDIATES) [CATALYTIC ACTIVITY 1: PHOSPHOSERINE + H(2)O = SERINE + PHOSPHATE].;Product=POSSIBLE TRANSMEMBRANE PHOSPHOLIPID BIOSYNTHESIS BIFUNCTIONAL ENZYME PLSC: PUTATIVE L-3-PHOSPHOSERINE PHOSPHATASE (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSP) (PSPASE) + 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE (1-AGP ACYLTRANSFERASE) (1-AGPAT) (LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE) (LPAAT);Comments=ML1245, len: 579 aa.  Possible plsC, a transmembrane phospholipid biosynthesis bifunctional enzyme, including L-3-phosphoserine phosphatase (EC 3.1.3.3) and 1-acyl-Sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51). The N-terminus is similar to several phosphoserine phosphatases e.g. Haemophilus influenzae SW:SERB_HAEIN (P44997) (795 aa), BlastP Expect 9.8 and the C-terminus is similar to many  Prokaryotic and Eukaryotic acyltransferases e.g. Salmonella typhimurium 1-acyl-SN-glycerol-3-phosphate acyltransferase SW:PLSC_SALTY (P26974) (245 aa), Fasta scores: E(): 1.4e-11, 35.3% identity in 167 aa overlap. Highly similar over entire protein to Mycobacterium tuberculosis putative transferase Rv2483c TR:O53208 (EMBL:AL021246) (580 aa), Fasta scores: E(): 0, 77.1% identity in 573 aa overlap. Contains Pfam match to entry PF01553 Acyltransferase, Acyltransferase.;UniProt_AC=Q9X7A9;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	2677270	2678766	.	+	0	Locus=ML2254;Name=otsA;Function=INVOLVED IN OSMOREGULATORY TREHALOSE BIOSYNTHESIS. Mycobacteria can produce trehalose from glucose 6-phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway) [CATALYTIC ACTIVITY: UDP-GLUCOSE + D-GLUCOSE 6-PHOSPHATE = UDP + ALPHA,ALPHA-TREHALOSE 6-PHOSPHATE].;Product=PROBABLE ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING] OTSA (TREHALOSE-6-PHOSPHATE SYNTHASE) (UDP-GLUCOSE-GLUCOSEPHOSPHATE GLUCOSYLTRANSFERASE) (TREHALOSEPHOSPHATE-UDP GLUCOSYLTRANSFERASE) (TREHALOSE-6-PHOSPHATE SYNTHETASE) (TREHALOSE-PHOSPHATE SYNTHASE) (TREHALOSE-PHOSPHATE SYNTHETASE) (TRANSGLUCOSYLASE) (TREHALOSEPHOSPHATE-UDP GLUCOSYL TRANSFERASE);Comments=ML2254, len: 498 aa. Probable otsA, trehalose-phosphate synthase (EC 2.4.1.15). Similar to Mycobacterium tuberculosis otsA or Rv3490 or MTCY13E12.43 TR:O06353 (EMBL:Z95390) (500 aa) fasta scores: E(): 0, 80.3% identity in 497 aa. Similar to Candida albicans alpha,alpha-trehalose-phosphate synthase [UDP-forming] tps1 SW:TPS1_CANAL (Q92410) (478 aa) fasta scores: E(): 0, 37.8% identity in 473 aa. Previously sequenced as TR:Q50167 (EMBL:U15187). Contains Pfam match to entry PF00982 TrehaloseP_syn, Trehalose-6-phosphate synthase domain.;UniProt_AC=Q50167;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	15426	15767	.	-	0	Locus=ML0010c;Name=ML0010c;Function=;Product=Possible membrane protein (pseudogene);Comments=ML0010c, len: 342 bp. Possible pseudogene of M. tuberculosis orthologue Rv0008c (438 bp) (Best blastx scores: 124);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	17483	18283	.	+	0	Locus=ML0014;Name=ML0014;Function=;Product=Probable conserved membrane protein (pseudogene);Comments=ML0014, len: 801 bp. Possible pseudogene of M. tuberculosis orthologue Rv0012 (789 bp) (Best blastx scores: 411);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	780285	780361	.	+	0	Locus=MLP000013;Name=metU;Function=;Product=tRNA-Met anticodon CAT;Comments=tRNA Met anticodon CAT, Cove scores: 88.77;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	663497	663988	.	+	0	Locus=ML0547;Name=ML0547;Function=;Product=Possible membrane protein (pseudogene);Comments=ML0547, len: 492 bp. Possible pseudogene of M. tuberculosis orthologue Rv1401 (603 bp) (Best blastx scores: 114);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	12856	13230	.	-	0	Locus=ML0008c;Name=ML0008c;Function=;Product=Hypothetical protein;Comments=ML0008c, len: 124 aa. Hypothetical unknown protein.;UniProt_AC=Q9CDF1;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	13775	13966	.	+	0	Locus=ML0009;Name=ML0009;Function=;Product=Hypothetical protein;Comments=ML0009, len: 63 aa. Hypothetical unknown protein.;UniProt_AC=Q9CDF0;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	4435	5004	.	+	0	Locus=ML0004;Name=ML0004;Function=;Product=Conserved hypothetical protein;Comments=ML0004, len: 189 aa. Conserved hypothetical protein (see citation below), similar to hypothetical proteins from mycobacteria e.g. Rv0004|P71573|AL123456 from M. tuberculosis  (187 aa), Fasta scores: E(): 0, (77.2% identity in 167 aa overlap). Previously sequenced as Q50181|Z70722 (199 aa), Fasta scores: E(): 0, (99.5% identity in 187 aa overlap).;UniProt_AC=Q9CDF4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	11195	12106	.	+	0	Locus=ML0007;Name=ML0007;Function=;Product=Possible conserved membrane protein;Comments=ML0007, len: 303 aa. Possible conserved membrane protein, similar to Rv0007|P71575|AL123456 possible conserved membrane protein from M. tuberculosis (304 aa), Fasta scores: E(): 0, (54.2% identity in 319 aa overlap). Previously sequenced as O32870|Z70722 (303 aa), Fasta scores: E(): 0, (99.7% identity in 303 aa overlap). Contains hydrophobic, possible membrane-spanning regions near the C-terminus. Contains a region identical to ML2630.;UniProt_AC=O32870;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	31015	31651	.	-	0	Locus=ML0026;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML0026, len: 637 bp. Possible pseudogene similar to M. tuberculosis PPE protein, most similar to PPE26|Rv1789 (Best blastx scores: 99), but similar to several others e.g. PPE31, PPE22, PPE14 etc.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	32113	32920	.	-	0	Locus=ML0027c;Name=ML0027c;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML0027c, len: 808 bp. Possible pseudogene of M. tuberculosis orthologue Rv0037c (1326 bp) (Best blastx scores: 178);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	12404	12479	.	+	0	Locus=MLP000002;Name=alaT;Function=;Product=tRNA-Ala anticodon TGC;Comments=tRNA Ala anticodon TGC, Cove scores: 86.68;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	28890	28972	.	+	0	Locus=MLP000003;Name=leuT;Function=;Product=tRNA-Leu anticodon CAG;Comments=tRNA Leu anticodon CAG, Cove scores: 63.58;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	207844	207954	.	-	0	Locus=ML0146c;Name=ML0146c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0146c, len: 111 bp. Possible pseudogene of M. tuberculosis orthologue Rv0941c (774 bp) (Best blastx scores: 108);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	206601	206740	.	-	0	Locus=ML0145c;Name=ML0145c;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML0145c, len: 140 bp. Possible transposase remnant, some similarity to Q9RBZ3 transposase from Pseudomonas syringae (1071 bp), (blastx scores: 51) and to Q44454|Z18270 transposase from Agrobacterium tumefaciens (1098 bp), (blastx scores: 41). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	39947	40211	.	+	0	Locus=ML0033;Name=ML0033;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0033, len: 265 bp. Possible pseudogene similar to M. tuberculosis ortholog Rv3906c (507 bp) (Best blastx scores: 95);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	40825	41032	.	+	0	Locus=ML0034;Name=esxC;Function=;Product=Putative ESAT-6 like protein esxC (pseudogene);Comments=ML0034, len: 208 bp. Possible pseudogene of M. tuberculosis orthologue Rv3890c (285 bp) (Best blastx scores: 54);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	42222	43083	.	+	0	Locus=ML0035;Name=ML0035;Function=;Product=Probable conserved membrane protein (pseudogene);Comments=ML0035, len: 862 bp. Possible pseudogene of M. tuberculosis orthologue Rv3888c (1023 bp) (Best blastx scores: 182);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	44077	45332	.	+	0	Locus=ML0037;Name=mycP2;Function=;Product=Probable alanine and proline rich membrane-anchored mycosin mycP2 (pseudogene);Comments=ML0037, len: 1256 bp. Possible pseudogene of M. tuberculosis orthologue Rv3886c|mycP2 (1650 bp) (Best blastx scores: 160);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	49689	49946	.	-	0	Locus=ML0040c;Name=ML0040c;Function=;Product=Probable transposase remnant (pseudogene);Comments=ML0040c, len: 258 bp. Possible transposase remnant, similar to the N-terminus of Rv2424c|P71924 probable transposase for IS1558 from M. tuberculosis (999 bp);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	235667	235822	.	+	0	Locus=ML0170;Name=ML0170;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0170, len: 156 bp. Possible pseudogene of M. tuberculosis orthologue Rv0965c (420 bp) (Best blastx scores: 115);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	711833	712695	.	+	0	Locus=ML0586;Name=ML0586;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0586, len: 863 bp. Possible pseudogene of M. tuberculosis orthologue Rv1455 (864 bp) (Best blastx scores: 414);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	28954	29265	.	-	0	Locus=ML0023c;Name=ML0023c;Function=;Product=Hypothetical protein;Comments=ML0023c, len: 103 aa. Hypothetical unknown protein. Improbable CDS, possibly the remains of a disrupted gene.;UniProt_AC=Q9CDE3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	29775	30026	.	+	0	Locus=ML0024;Name=ML0024;Function=;Product=Hypothetical protein;Comments=ML0024, len: 83 aa. Hypothetical unknown protein.;UniProt_AC=Q9CDE2;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	30293	30583	.	-	0	Locus=ML0025c;Name=ML0025c;Function=;Product=Hypothetical protein;Comments=ML0025c, len: 96 aa. Hypothetical unknown protein.;UniProt_AC=Q9CDE1;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	33100	33705	.	+	0	Locus=ML0028;Name=ML0028;Function=;Product=Conserved hypothetical protein;Comments=ML0028, len: 201 aa. Conserved hypothetical protein, highly similar to Rv0038|P71608|AL123456 hypothetical protein from M. tuberculosis (202 aa), Fasta scores: E(): 0, (88.1% identity in 202 aa overlap). Similar to CAB72194|AL138851 hypothetical protein SCE59.07C from Streptomyces coelicolor (193 aa), Fasta scores: E(): 3.5e-28, (45.6% identity in 182 aa overlap) and shows weak similarity to many other bacterial hypothetical proteins. Previously sequenced as Q50191|Z70722 (202 aa), Fasta scores: E(): 0, (100.0% identity in 201 aa overlap).;UniProt_AC=Q50191;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	tRNA	165035	165127	.	+	0	Locus=MLP000005;Name=serT;Function=;Product=tRNA-Ser anticodon GCT;Comments=tRNA Ser anticodon GCT, Cove scores: 56.23;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	165147	165219	.	+	0	Locus=MLP000006;Name=argU;Function=;Product=tRNA-Arg anticodon ACG;Comments=tRNA Arg anticodon ACG, Cove scores: 76.52;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	73832	74366	.	-	0	Locus=ML0059c;Name=ML0059c;Function=;Product=Hypothetical alanine rich protein (pseudogene);Comments=ML0059c, len: 535 bp. Possible pseudogene of M. tuberculosis orthologue Rv3863 (1176 bp) (Best blastx scores: 119);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	76494	76713	.	-	0	Locus=ML0060c;Name=ML0060c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0060c, len: 220 bp. Possible pseudogene of M. tuberculosis orthologue Rv3860 (1170 bp) (Best blastx scores: 354);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	84980	85727	.	+	0	Locus=ML0063;Name=ML0063;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0063, len: 748 bp. Possible pseudogene of M. tuberculosis orthologue Rv3856c (1005 bp) (Best blastx scores: 211);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	271901	271976	.	+	0	Locus=MLP000008;Name=thrU;Function=;Product=tRNA-Thr anticodon CGT;Comments=tRNA Thr anticodon CGT, Cove scores: 85.20;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	236614	237352	.	+	0	Locus=ML0171;Name=ML0171;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0171, len: 739 bp. Possible pseudogene of M. tuberculosis orthologue Rv0963c (801 bp) (Best blastx scores: 311);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	237609	238202	.	+	0	Locus=ML0172;Name=lprP;Function=;Product=Possible lipoprotein LprP (pseudogene);Comments=ML0172, len: 594 bp. Possible pseudogene of M. tuberculosis orthologue lprP|Rv0962c (675 bp) (Best blastx scores: 310);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	89620	90336	.	-	0	Locus=ML0068c;Name=ML0068c;Function=;Product=Conserved hypothetical protein;Comments=ML0068c, len: 238 aa. Conserved hypothetical protein, highly similar to Rv3850|P96227|AL123456 hypothetical protein from M. tuberculosis (218 aa), Fasta scores: E(): 0, (78.3% identity in 217 aa overlap).;UniProt_AC=Q9CDD0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	90521	90919	.	-	0	Locus=ML0069c;Name=ML0069c;Function=;Product=Conserved hypothetical protein;Comments=ML0069c, len: 132 aa. Conserved hypothetical protein, highly similar to Rv3849|P96228|AL123456) hypothetical protein from M. tuberculosis (132 aa), Fasta scores: E(): 0, (84.0% identity in 131 aa overlap).;UniProt_AC=Q9CDC9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	91296	91559	.	-	0	Locus=ML0070c;Name=ML0070c;Function=;Product=Hypothetical protein;Comments=ML0070c, len: 87 aa. Hypothetical unknown protein.;UniProt_AC=Q9CDC8;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	62201	63109	.	-	0	Locus=ML0051c;Name=PPE68;Function=;Product=PPE family protein;Comments=ML0051c, len: 302 aa. Member of the Mycobacteria PPE family. Similar to Rv3873|O69738|AL123456 PPE-family protein from M. tuberculosis (368 aa), Fasta scores: E(): 6.1e-32, (46.2% identity in 288 aa overlap). Lacks the PPE motif at the N-terminus. N-terminus is similar to the N-termini of ML0539, ML1828 and ML1991. Previously sequenced as O33085|Y14967 (302 aa), Fasta scores: E(): 0, (100.0% identity in 302 aa overlap). Contains Pfam match to entry PF00823 PPE, PPE family.;UniProt_AC=O33085;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	95965	96439	.	-	0	Locus=ML0075c;Name=bfrB;Function=;Product=Possible bacterioferritin BfrB (pseudogene);Comments=ML0075c, len: 475 bp. Possible pseudogene of M. tuberculosis orthologue bfrB|Rv3841 (546 bp) (Best blastx scores: 190);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	97037	97282	.	-	0	Locus=ML0076c;Name=ML0076c;Function=;Product=Possible transcriptional regulator protein (pseudogene);Comments=ML0076c, len: 246 bp. Possible pseudogene of M. tuberculosis orthologue Rv3840 (414 bp) (Best blastx scores: 196);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	97832	98119	.	-	0	Locus=ML0077c;Name=ML0077c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0077c, len: 288 bp. Possible pseudogene of M. tuberculosis orthologue Rv3839 (777 bp) (Best blastx scores: 251);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	100374	100651	.	-	0	Locus=ML0080c;Name=ML0080c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0080c, len: 278 bp. Possible pseudogene of M. tuberculosis orthologue Rv3836 (414 bp) (Best blastx scores: 137);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	105732	106191	.	-	0	Locus=ML0083c;Name=ML0083c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0083c, len: 460 bp. Possible pseudogene of M. tuberculosis orthologue Rv3831 (483 bp) (Best blastx scores: 151);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	106286	106599	.	-	0	Locus=ML0084c;Name=ML0084c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0084c, len: 314 bp. Possible pseudogene of M. tuberculosis orthologue Rv3819 (336 bp) (Best blastx scores: 138);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	106635	108159	.	-	0	Locus=ML0085c;Name=ML0085c;Function=;Product=hypothetical protein (pseudogene);Comments=ML0085c, len: 1525 bp. Possible pseudogene of M. tuberculosis orthologue Rv3818 (1551 bp) (Best blastx scores: 275).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	108258	108991	.	-	0	Locus=ML0086c;Name=ML0086c;Function=;Product=Possible phosphotransferase (pseudogene);Comments=ML0086c, len: 734 bp. Possible pseudogene of M. tuberculosis orthologue Rv3817 (756 bp) (Best blastx scores: 203);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	109842	110234	.	+	0	Locus=ML0088;Name=ML0088;Function=;Product=Possible acyltransferase (pseudogene);Comments=ML0088, len: 393 bp. Possible pseudogene of M. tuberculosis orthologue Rv3815c (756 bp) (Best blastx scores: 228);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	111660	112884	.	-	0	Locus=ML0090c;Name=ML0090c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0090c, len: 1225 bp. Possible pseudogene of M. tuberculosis orthologue Rv3811 (1620 bp) (Best blastx scores: 228);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	227008	227286	.	-	0	Locus=ML0162c;Name=ML0162c;Function=;Product=Hypothetical protein;Comments=ML0162c, len: 92 aa. Hypothetical unknown protein. Improbable CDS suggested by GC frameplot. Possibly the remains of a disrupted gene. Previously sequenced as Q9Z5H3|AL035500 (92 aa), Fasta scores: E(): 0, (98.9% identity in 92 aa overlap).;UniProt_AC=Q9Z5H3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	205253	206396	.	-	0	Locus=ML0144c;Name=ML0144c;Function=;Product=Putative group II intron maturase-related protein (pseudogene);Comments=ML0144c, len: 1144 bp. Possible pseudogene, similar to several maturases e.g. Q9MD87|AF218567 putative maturase from Cryphonectria parasitica (Cheshnut blight fungus) (2334 bp), (blastx scores: 143); and Rv0071|O53616 Putative maturase from M. tuberculosis (705 bp), (blastx scores: 153). Belongs to the LEPREP family of dispersed repeats (see citation below);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	524676	524751	.	-	0	Locus=MLP000011;Name=lysU;Function=;Product=tRNA-Lys anticodon CTT;Comments=tRNA Lys anticodon CTT, Cove scores: 84.12;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	526169	526244	.	-	0	Locus=MLP000012;Name=hisT;Function=;Product=tRNA-His anticodon GTG;Comments=tRNA His anticodon GTG, Cove scores: 82.48;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	340549	341173	.	-	0	Locus=ML0261c;Name=trcR;Function=;Product=Two-component transcriptional regulator TrcR (pseudogene);Comments=ML0261c, len: 625 bp. Possible pseudogene of M. tuberculosis orthologue Rv1033c|trcR (774 bp) (Best blastx scores: 192).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	109049	109822	.	+	0	Locus=ML0087;Name=ML0087;Function=;Product=Possible acyltransferase;Comments=ML0087, len: 257 aa. Possible acyltransferase (EC 2.3.1.-), highly similar to Rv3816c|O07807|AL123456 possible acyltransferase from M. tuberculosis (259 aa), Fasta scores: E(): 0, (81.5% identity in 254 aa overlap). Also similar to the neighboring putative acyltransferases in M. tuberculosis, Rv3815c and Rv3814c. Also similar to ML0892. Shows similarity to many putative bacterial acyltransferases. Contains Pfam match to entry PF01553 Acyltransferase, Acyltransferase.;UniProt_AC=Q9CDC0;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	133849	135036	.	-	0	Locus=ML0103c;Name=fadE35;Function=;Product=Probable acyl-CoA dehydrogenase FadE35 (pseudogene);Comments=ML0103c, len: 1188 bp. Possible pseudogene of M. tuberculosis orthologue fadE35|Rv3797 (1782 bp) (Best blastx scores: 159);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	990847	990919	.	+	0	Locus=MLP000014;Name=asnT;Function=;Product=tRNA-Asn anticodon GTT;Comments=tRNA Asn anticodon GTT, Cove scores: 78.91;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	341956	342250	.	-	0	Locus=ML0262c;Name=esxJ;Function=;Product=Putative ESAT-6 like protein EsxJ (pseudogene);Comments=ML0262c, len: 295 bp. Probable pseudogene of M. tuberculosis orthologue Rv1038c (297 bp) (Best blastx scores: 310);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	123370	124380	.	+	0	Locus=ML0099;Name=ML0099;Function=;Product=Probable conserved membrane protein;Comments=ML0099, len: 336 aa. Probable conserved membrane protein, highly similar to Rv3802c|O53581|AL123456 hypothetical protein from M. tuberculosis (336 aa), Fasta scores: E(): 0, (75.5% identity in 335 aa overlap). Contains hydrophobic, possible membrane-spanning region near the N-terminus;UniProt_AC=Q9CDB3;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	152204	152371	.	-	0	Locus=ML0111c;Name=ML0111c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0111c, len: 168 bp. Possible pseudogene of M. tuberculosis orthologue Rv3788 (486 bp) (Best blastx scores: 157);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	310900	311580	.	+	0	Locus=ML0237;Name=ML0237;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0237, len: 681 bp. Possible pseudogene of M. tuberculosis orthologue Rv1006 (1704 bp) (Best blastx scores: 389);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	164082	164876	.	-	0	Locus=ML0122c;Name=hisC2;Function=;Product=Probable histidinol-phosphate aminotransferase HisC2 (pseudogene);Comments=ML0122c, len: 795 bp. Possible pseudogene of M. tuberculosis orthologue Rv3772|hisC2 (1062 bp) (Best blastx scores: 574). Also similar to ML1830c a possible pseudogene similar to M. tuberculosis hisC2.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	166460	166833	.	+	0	Locus=ML0123;Name=ML0123;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0123, len: 376 bp. Possible pseudogene of M. tuberculosis orthologue Rv3767c (945 bp) (Best blastx scores: 169);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	360751	361125	.	+	0	Locus=ML0278;Name=ML0278;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0278, len: 375 bp. Possible pseudogene similar to M. tuberculosis ortholog Rv0387c (735 bp) (Best blastx scores: 97).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1117523	1117780	.	-	0	Locus=ML0947c;Name=ML0947c;Function=;Product=hypothetical protein;Comments=ML0947c, len: 85 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCD2;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	150128	151510	.	-	0	Locus=ML0109c;Name=ML0109c;Function=;Product=Probable oxidoreductase;Comments=ML0109c, len: 460 aa. Probable oxidoreductase (EC 1.-.-.-), highly similar to Rv3790|P72056|AL123456) probable oxidoreductase from M. tuberculosis (461 aa), Fasta scores: E(): 0, (86.6% identity in 461 aa overlap). Also similar to many bacterial putative oxidoreductases. Contains Pfam match to entry PF01565 FAD_binding_4, FAD binding domain.;UniProt_AC=Q9CDA4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	751048	751489	.	+	0	Locus=ML0618;Name=cysA1;Function=;Product=Probable sulphate transport ATP-binding protein ABC transporter CysA1 (pseudogene);Comments=ML0618, len: 442 bp. Possible pseudogene of M. tuberculosis orthologue cysA1|Rv2397c  (1056 bp) (Best blastx scores: 153).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	171616	172923	.	+	0	Locus=ML0128;Name=ML0128;Function=;Product=Possible glycosyl transferase;Comments=ML0128, len: 435 aa. Possible glycosyl transferase (EC 2.4.1.-) (see citation below), highly similar to the possible glycosyl transferase from M. tuberculosis e.g. Rv2958c|P95134|AL123456 (428 aa), Fasta scores: E(): 0, (75.1% identity in 417 aa overlap) and Rv2962c|P95130|AL123456 (449 aa), Fasta scores: E(): 0, (74.4% identity in 425 aa overlap). Similar to Q9ZGH7|AF079762 desVII, glycosyl transferase from a macrolide antibiotic biosynthesis gene cluster in Streptomyces venezuelae (426 aa), Fasta scores: E(): 1.1e-09, (30.9% identity in 223 aa overlap). Shows similarity to bacterial and eukaryotic glycosyl transferases. Also similar to ML0125 and shows weaker similarity to ML0985 from M. leprae.;UniProt_AC=Q9CD88;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	200930	201848	.	+	0	Locus=ML0140;Name=ML0140;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0140, len: 919 bp. Possible pseudogene similar to M. tuberculosis Rv0221 (1410 bp) (Best blastx scores: 157);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	204890	204988	.	-	0	Locus=ML0143c;Name=ML0143c;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML0143c, len: 99 bp. Possible transposase remnant, similar to Q44454|Z18270 transposase from Agrobacterium tumefaciens (1098 bp), (blastx scores: 93); and to Q9R9U9|AJ245436 transposase tnpa1 from Pseudomonas putida (1065 bp), (blastx scores: 89). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	188551	189252	.	+	0	Locus=ML0136;Name=lppX;Function=;Product=Probable conserved lipoprotein LppX;Comments=ML0136, len: 233 aa. Probable lppX, conserved lipoprotein, highly similar to Rv2945c|LPPX_MYCTU|Z83858 lppX, conserved lipoprotein from M. tuberculosis (233 aa), Fasta scores: E(): 0, (76.4% identity in 233 aa overlap); and similar to other probable mycobacterial lipoproteins e.g. LPRG_MYCTU|AJ000500 lprG, 27 kDa lipoprotein antigen from Mycobacterium bovis (236 aa), Fasta scores: E(): 2.5e-13, (31.2% identity in 202 aa overlap). And is similar to ML0557 from M. leprae. Contains a probable N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9CD80;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	tRNA	1531701	1531777	.	-	0	Locus=MLP000021;Name=leuV;Function=;Product=tRNA-Leu anticodon CAA;Comments=tRNA Leu anticodon CAA, Cove scores: 48.78;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	209823	210314	.	+	0	Locus=ML0148;Name=ML0148;Function=;Product=Possible formamidopyrimidine-DNA glycosylase (pseudogene);Comments=ML0148, len: 492 bp. Possible pseudogene of M. tuberculosis orthologue Rv0944 (477 bp) (Best blastx scores: 261);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	210338	211058	.	+	0	Locus=ML0149;Name=ML0149;Function=;Product=Probable short-chain dehydrogenase/reductase (pseudogene);Comments=ML0149, len: 721 bp. Possible pseudogene of M. tuberculosis orthologue Rv0945 (762 bp) (Best blastx scores: 196);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	764434	765813	.	-	0	Locus=ML0632c;Name=amiA2;Function=;Product=Probable amidase AmiA2 (pseudogene);Comments=ML0632c, len: 1380 bp. Possible pseudogene of M. tuberculosis orthologue amiA2|Rv2363 (Best blastx scores: 975);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	204363	204611	.	+	0	Locus=ML0142;Name=ML0142;Function=;Product=Probable membrane protein;Comments=ML0142, len: 82 aa. Probable membrane protein. Contains hydrophobic, possible membrane-spanning region.;UniProt_AC=Q9CD76;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	214001	214189	.	+	0	Locus=ML0152;Name=ML0152;Function=;Product=Hypothetical protein;Comments=ML0152, len: 62 aa. Improbable CDS suggested by GC frameplot. Possibly the remains of a disrupted gene.;UniProt_AC=Q9CD73;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	208911	209279	.	+	0	Locus=ML0147;Name=ML0147;Function=;Product=conserved hypothetical protein (pseudogene);Comments=ML0147, len: 369 bp. Possible pseudogene similar to the N-terminal region (non-repetitive domains) of several M. tuberculosis PE-family proteins e.g. Rv1803c|O53952|AL123456 PE_family, PGRS-subfamily protein (1917 bp). The start codon appears to have been mutated (ATG to ATA).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	213175	213492	.	-	0	Locus=ML0151c;Name=ML0151c;Function=;Product=Conserved hypothetical protein;Comments=ML0151c, len: 105 aa. Conserved hypothetical protein, highly similar to Rv0948c|Y948_MYCTU|P71562 hypothetical protein from M. tuberculosis (105 aa), Fasta scores: E(): 1.9e-32, (83.8% identity in 105 aa overlap). Also similar to CAB82023|AL161755 hypothetical protein SCD63.16C from Streptomyces coelicolor (110 aa), Fasta scores: E(): 3.9e-06, (44.4% identity in 72 aa overlap); and to the N-terminus of two chorismate mutase/prephenate dehydratase.;UniProt_AC=Q9CD74;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	220591	221452	.	-	0	Locus=ML0157c;Name=ML0157c;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML0157c, len: 862 bp. Possible pseudogene of M. tuberculosis orthologue Rv0953c (849 bp) (Best blastx scores: 518);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	1535955	1536040	.	-	0	Locus=MLP000022;Name=leuU;Function=;Product=tRNA-Leu anticodon GAG;Comments=tRNA Leu anticodon GAG, Cove scores: 59.66;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	1602380	1602454	.	-	0	Locus=MLP000023;Name=valU;Function=;Product=tRNA-Val anticodon GAC;Comments=tRNA Val anticodon GAC, Cove scores: 88.42;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	228347	229628	.	+	0	Locus=ML0163;Name=ML0163;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0163, len: 1282 bp. Possible pseudogene of M. tuberculosis orthologue Rv0959 (2019 bp) (Best blastx scores: 266);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	229629	230493	.	+	0	Locus=ML0164;Name=fadE13;Function=;Product=Probable acyl-CoA dehydrogenase FadE13 (pseudogene);Comments=ML0164, len: 865 bp. Possible pseudogene of M. tuberculosis orthologue fadE13|Rv0975c (1149 bp)  (Best blastx scores: 280);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	230546	231663	.	+	0	Locus=ML0165;Name=accD2;Function=;Product=Probable acetyl-/propionyl-CoA carboxylase (beta subunit) AccD2 (pseudogene);Comments=ML0165, len: 1118 bp. Possible pseudogene of M. tuberculosis orthologue accD2|Rv0974c (1590 bp) (Best blastx scores: 451).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	231672	233398	.	+	0	Locus=ML0166;Name=accA2;Function=;Product=Probable acetyl-/propionyl-CoA carboxylase (alpha subunit) AccA2 (pseudogene);Comments=ML0166, len: 1727 bp. Possible pseudogene of M. tuberculosis orthologue accA2|Rv0973c (2004 bp) (Best blastx scores: 317);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	233449	234077	.	+	0	Locus=ML0167;Name=fadE12;Function=;Product=Probable acyl-CoA dehydrogenase FadE12 (pseudogene);Comments=ML0167, len: 629 bp. Possible pseudogene of M. tuberculosis orthologue fadE12|Rv0972c (1167 bp) (Best blastx scores: 396);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	234124	234820	.	+	0	Locus=ML0168;Name=echA7;Function=;Product=Probable enoyl-CoA hydratase EchA7 (pseudogene);Comments=ML0168, len: 697 bp. Possible pseudogene of M. tuberculosis orthologue echA7|Rv0971c (810 bp) (Best blastx scores: 174);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	767601	767933	.	+	0	Locus=ML0635;Name=ML0635;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0635, len: 333 bp. Possible pseudogene of M. tuberculosis orthologue Rv2360c (429 bp) (Best blastx scores: 192).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	221657	222601	.	+	0	Locus=ML0158;Name=ML0158;Function=;Product=Probable conserved transmembrane protein;Comments=ML0158, len: 314 aa. Probable conserved transmembrane protein, similar to Rv0954|34KD_MYCTU|P71556 conserved transmembrane protein from M. tuberculosis (303 aa), Fasta scores: E(): 0, (55.8% identity in 312 aa overlap) and to 34KD_MYCPA|Q04959 34 kDa antigenic protein from Mycobacterium paratuberculosis (298 aa), Fasta scores: E(): 0, (61.7% identity in 311 aa overlap). Previously sequenced as O87894|U82111 (336 aa), Fasta scores: E(): 0, (99.7% identity in 314 aa overlap). Contains hydrophobic, membrane-spanning regions.;UniProt_AC=Q9CD70;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	tRNA	1602469	1602542	.	-	0	Locus=MLP000024;Name=cysU;Function=;Product=tRNA-Cys anticodon GCA;Comments=tRNA Cys anticodon GCA, Cove scores: 68.63;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	1602568	1602643	.	-	0	Locus=MLP000025;Name=glyT;Function=;Product=tRNA-Gly anticodon GCC;Comments=tRNA Gly anticodon GCC, Cove scores: 89.46;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	245324	245983	.	-	0	Locus=ML0179c;Name=ML0179c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0179c, len: 660 bp. Probable pseudogene of M. tuberculosis orthologue Rv0990c (657 bp) (Best blastx scores: 338);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	339324	340503	.	-	0	Locus=ML0260c;Name=trcS;Function=;Product=Two component sensor histidine kinase TrcS (pseudogene);Comments=ML0260c, len: 1180 bp. Possible pseudogene of M. tuberculosis orthologue Rv1032c (1530 bp) (Best blastx scores: 284);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	240237	240410	.	+	0	Locus=ML0173;Name=rpmF;Function=;Product=Probable 50S ribosomal protein L32 RpmF;Comments=ML0173, len: 57 aa. Probable rpmF, ribosomal protein L32, similar to many e.g. Rv0979A|P58287|RL32_MYCTU 50S ribosomal protein L32 from M. tuberculosis (57 aa), fasta scores: E(): 4.9e-19, (84.2.462% identity in 57 aa overlap); and R322_STRCO|Q9RL50 probable 50S ribosomal protein from Streptomyces coelicolor (56 aa), fasta scores: E(): 1.5e-09, (63.462% identity in 52 aa overlap). Belongs to the L32P family of ribosomal proteins.;UniProt_AC=Q9CD69;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	251982	252266	.	+	0	Locus=ML0186;Name=ML0186;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0186, len: 285 bp. Possible pseudogene of M. tuberculosis orthologue Rv0997 (432 bp) (Best blastx scores: 101);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	1602822	1602896	.	+	0	Locus=MLP000026;Name=valT;Function=;Product=tRNA-Val anticodon CAC;Comments=tRNA Val anticodon CAC, Cove scores: 85.25;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	254397	255092	.	+	0	Locus=ML0189;Name=ML0189;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0189, len: 696 bp. Possible pseudogene of M. tuberculosis orthologue Rv0999 (759 bp) (Best blastx scores: 400);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	255879	256895	.	+	0	Locus=ML0191;Name=arcA;Function=;Product=Probable arginine deiminase ArcA (pseudogene);Comments=ML0191, len: 1017 bp. Possible pseudogene of M. tuberculosis orthologue arcA|Rv1001 (1209 bp) (Best blastx scores: 249);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	261342	262320	.	-	0	Locus=ML0195c;Name=ML0195c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0195c, len: 979 bp. Possible pseudogene of M. tuberculosis orthologue Rv3651 (1038 bp) (Best blastx scores: 218);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	263238	264560	.	-	0	Locus=ML0197c;Name=ML0197c;Function=;Product=Probable helicase (pseudogene);Comments=ML0197c, len: 1323 bp. Possible pseudogene of M. tuberculosis orthologue Rv3649 (2316 bp) (Best blastx scores: 213);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	783903	785174	.	-	0	Locus=ML0647c;Name=aofH;Function=;Product=Probable flavin-containing monoamine oxidase AofH (pseudogene);Comments=ML0647c, len: 1272 bp. Possible pseudogene of M. tuberculosis orthologue Rv3170|aofH (1347 bp) (Best blastx scores: 441);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	254028	254291	.	+	0	Locus=ML0188;Name=ML0188;Function=;Product=Hypothetical protein;Comments=ML0188, len: 87 aa. Hypothetical unknown protein. Contains PS01047 Heavy-metal-associated domain.;UniProt_AC=Q9CD63;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	252658	253719	.	+	0	Locus=ML0187;Name=ML0187;Function=;Product=Conserved hypothetical protein;Comments=ML0187, len: 353 aa. Conserved hypothetical protein, highly similar to Rv0998|O05581|AL123456 conserved hypothetical protein, possibly cyclic nucleotide-dependent protein kinase from M. tuberculosis (333 aa), Fasta scores: E(): 0, (69.7% identity in 330 aa overlap); and similar to many hypothetical proteins. Contains Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain. Contains PS00889 Cyclic nucleotide-binding domain signature 2.;UniProt_AC=Q9CD64;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	277944	279039	.	+	0	Locus=ML0206;Name=ML0206;Function=;Product=Probable conserved integral membrane (pseudogene);Comments=ML0206, len: 1096 bp. Possible pseudogene of M. tuberculosis orthologue Rv3630 (1296 bp) (Best blastx scores: 392);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	280783	281282	.	-	0	Locus=ML0209c;Name=ML0209c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0209c, len: 500 bp. Possible pseudogene similar to M. tuberculosis Rv1748 (732 bp) (Best blastx scores: 146);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	273290	274999	.	-	0	Locus=ML0203c;Name=ML0203c;Function=;Product=Probable conserved transmembrane protein;Comments=ML0203c, len: 569 aa. Probable conserved transmembrane protein, highly similar to Rv3635|O06372|AL123456 probable transmembrane protein from M. tuberculosis (591 aa), Fasta scores: E(): 0, (77.2% identity in 569 aa overlap). Previously sequenced as O69545|AL023093 (569 aa), Fasta scores: E(): 0, (99.8% identity in 569 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=O69545;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	279784	280125	.	+	0	Locus=ML0208;Name=ML0208;Function=;Product=Possible conserved membrane protein;Comments=ML0208, len: 113 aa. Possible conserved membrane protein, highly similar to Rv3632|O06375|AL123456 conserved membrane protein from M. tuberculosis (114 aa), Fasta scores: E(): 0, (82.0% identity in 111 aa overlap). Previously sequenced as O69541|AL023093 (113 aa), Fasta scores: E(): 0, (100.0% identity in 113 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=O69541;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	283539	284579	.	+	0	Locus=ML0212;Name=ML0212;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0212, len: 1041 bp. Probable pseudogene of M. tuberculosis orthologue Rv3626c (1053 bp) (Best blastx scores: 1003);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	286276	286674	.	-	0	Locus=ML0215c;Name=lpqG;Function=;Product=Probable conserved lipoprotein LpqG (pseudogene);Comments=ML0215c, len: 399 bp. Possible pseudogene of M. tuberculosis orthologue lpqG|Rv3623 (723 bp) (Best blastx scores: 222).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	286829	287302	.	-	0	Locus=ML0216c;Name=ML0216c;Function=;Product=Conserved 13E12 repeat family protein (pseudogene);Comments=ML0216c, len: 474 bp. Possible pseudogene similar to M. tuberculosis Rv0393 (1326 bp) (Best blastx scores: 102);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	290378	290991	.	-	0	Locus=ML0219c;Name=ML0219c;Function=;Product=Possible dehydrogenase (pseudogene);Comments=ML0219c, len: 614 bp. Possible pseudogene similar to M. tuberculosis Rv3729 (1191 bp) (Best blastx scores: 114);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	291435	292461	.	-	0	Locus=ML0220c;Name=ML0220c;Function=;Product=Possible monooxygenase (pseudogene);Comments=ML0220c, len: 1027 bp. Possible pseudogene of M. tuberculosis orthologue Rv3618 (1188 bp) (Best blastx scores: 208). Also similar to ML1984c a possible pseudogene similar to M. tuberculosis Rv3618.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	292471	293353	.	-	0	Locus=ML0221c;Name=ephA;Function=;Product=Probable epoxide hydrolase EphA (pseudogene);Comments=ML0221c, len: 883 bp. Possible pseudogene of M. tuberculosis orthologue ephA|Rv3617 (969 bp) (Best blastx scores: 177).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	1785229	1785299	.	+	0	Locus=MLP000029;Name=glyV;Function=;Product=tRNA-Gly anticodon TCC;Comments=tRNA Gly anticodon TCC, Cove scores: 63.84;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	1987247	1987321	.	-	0	Locus=MLP000030;Name=valV;Function=;Product=tRNA-Val anticodon TAC;Comments=tRNA Val anticodon TAC, Cove scores: 84.14;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	288678	288923	.	+	0	Locus=ML0217;Name=ML0217;Function=;Product=Hypothetical protein;Comments=ML0217, len: 81 aa. Hypothetical unknown protein. Possibly the remains of a disrupted gene.;UniProt_AC=Q9CD59;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	289829	290215	.	-	0	Locus=ML0218c;Name=ML0218c;Function=;Product=Hypothetical protein;Comments=ML0218c, len: 128 aa. Hypothetical unknown protein. Improbable CDS suggested by GC frameplot. Possibly the remains of a disrupted gene. Previously sequenced as O69534|AL023093 (128 aa), Fasta scores: E(): 0, (99.2% identity in 128 aa overlap).;UniProt_AC=O69534;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	793593	793874	.	-	0	Locus=ML0656c;Name=ML0656c;Function=;Product=Hypothetical protein;Comments=ML0656c, len: 93 aa. Hypothetical protein. Previously sequenced as O32893|Z98271 (93 aa), Fasta scores: E(): 0, (100.0% identity in 93 aa overlap).;UniProt_AC=O32893;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	tRNA	2033113	2033188	.	-	0	Locus=MLP000031;Name=gluU;Function=;Product=tRNA-Glu anticodon CTC;Comments=tRNA Glu anticodon CTC, Cove scores: 62.17;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2033276	2033350	.	-	0	Locus=MLP000032;Name=glnU;Function=;Product=tRNA-Gln anticodon CTG;Comments=tRNA Gln anticodon CTG, Cove scores: 56.59;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	795538	795864	.	-	0	Locus=ML0659c;Name=ML0659c;Function=;Product=Hypothetical protein;Comments=ML0659c, len: 108 aa. Hypothetical protein. Previously sequenced as O32892|Z98271 (108 aa), Fasta scores: E(): 0, (100.0% identity in 108 aa overlap).;UniProt_AC=O32892;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	296696	297550	.	+	0	Locus=ML0224;Name=folP1;Function=Involved in dihydrofolate biosynthesis (at the second step). Catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide [Catalytic activity: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate  = pyrophosphate + dihydropteroate].;Product=Probable dihydropteroate synthase 1 FolP1 (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate dipyrophosphorylase 1);Comments=ML0224, len: 284 aa. Probable folP1, dihydropteroate synthase 1 (EC 2.5.1.15), highly similar to Rv3608c|DHP1_MYCTU|O06274 probable folP1, dihydropteroate synthase 1 from M. tuberculosis  (280 aa), Fasta scores: E(): 0, (76.8% identity in 284 aa overlap); and similar to many others e.g. P28822|DHPS_BACSU dihydropteroate synthase from Bacillus subtilis (285 aa). Previously sequenced as O69530|AL023093 (284 aa), Fasta scores: E(): 0, (99.6% identity in 284 aa overlap). Also similar to ML1063 from M. leprae. Mutations in this gene result in diaminodiphenylsulfone resistance. Contains Pfam match to entry PF00809 DHPS, Dihydropteroate synthase. Contains PS00793 Dihydropteroate synthase signature 2.;UniProt_AC=P0C0X1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	tRNA	2133851	2133926	.	-	0	Locus=MLP000033;Name=alaU;Function=;Product=tRNA-Ala anticodon GGC;Comments=tRNA Ala anticodon GGC, Cove scores: 82.89;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2135501	2135574	.	-	0	Locus=MLP000034;Name=metV;Function=;Product=tRNA-Met anticodon CAT;Comments=tRNA Met anticodon CAT, Cove scores: 90.06;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	814146	814373	.	+	0	Locus=ML0679;Name=ML0679;Function=;Product=Hypothetical protein;Comments=ML0679, len: 75 aa. Hypothetical protein.;UniProt_AC=Q9CCM3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	305368	305706	.	+	0	Locus=ML0234;Name=lsr2;Function=;Product=Lsr2 protein precursor (15 kDa antigen)(A15);Comments=ML0234, len: 112 aa. lsr2, highly similar to Rv3597c|LSR2_MYCTU|O06285 lsr2, probable lsr protein from M. tuberculosis (112 aa), Fasta scores: E(): 0, (92.9% identity in 112 aa overlap). Homologues also occur in Streptomyces coelicolor e.g. Q9X8N1|AL049628 putative lsr2-like protein SCE94.26C (111 aa), Fasta scores: E(): 7.3e-18, (56.3% identity in 112 aa overlap). ;UniProt_AC=P24094;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	309643	310899	.	-	0	Locus=ML0236c;Name=pabB;Function=;Product=Probable para-aminobenzoate synthase component I PabB;Comments=ML0236c, len: 418 aa. Probable pabB, para-aminobenzoate synthase component I (EC 4.1.3.-), highly similar to Rv1005c|O05591|Z94752 pabB, putative para-aminobenzoate synthase component I from M. tuberculosis (458 aa), Fasta scores: E(): 0, (79.1% identity in 412 aa overlap). Similar to many others e.g. PABB_ECOLI|P05041 pabB, para-aminobenzoate synthase component I from Escherichia coli (453 aa), Fasta scores: E(): 5.5e-31, (35.2% identity in 378 aa overlap). Also similar to the C-terminal halves of ML0808 and ML1269 from M. leprae. When compared to the predicted M. tuberculosis translation, this CDS is missing the N-terminal 30 aa, thus it may be a pseudogene. Contains Pfam match to entry PF00425 chorismate_bind, chorismate binding enzyme.;UniProt_AC=Q7AQL1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	344904	345275	.	-	0	Locus=ML0264c;Name=ML0264c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0264c, len: 372 bp. Possible pseudogene similar to M. tuberculosis Rv2775 (462 bp) (Best blastx scores: 95);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	346709	347435	.	+	0	Locus=ML0266;Name=ML0266;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0266, len: 727 bp. Possible pseudogene similar to M. tuberculosis orthologue Rv1056 (765 bp) (Best blastx scores: 289);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	350965	351892	.	-	0	Locus=ML0267c;Name=ackA;Function=;Product=Probable acetate kinase AckA (pseudogene);Comments=ML0267c, len: 928 bp. Possible pseudogene of M. tuberculosis orthologue ackA|Rv0409 (1158 bp) (Best blastx scores: 257);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	326387	326995	.	+	0	Locus=ML0250;Name=ML0250;Function=;Product=Probable transcriptional regulatory protein (Probably TetR-family) (pseudogene);Comments=ML0250, len: 609 bp. Possible pseudogene of M. tuberculosis orthologue Rv1019 (594 bp) (Best blastx scores: 404);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	327120	327945	.	-	0	Locus=ML0251c;Name=ML0251c;Function=;Product=Probable diaminopimelate decarboxylase (pseudogene);Comments=ML0251c, len: 829 bp. Possible pseudogene similar to M. tuberculosis lysA|Rv1293 (1341 bp) (Best blastx scores: 114), also similar to ML1128 a possible orthologue of M. tuberculosis lysA.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	331780	332529	.	+	0	Locus=ML0253;Name=ML0253;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0253, len: 750 bp. Possible pseudogene of M. tuberculosis orthologue Rv1021 (978 bp) (Best blastx scores: 252).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	2292908	2292980	.	-	0	Locus=MLP000035;Name=trpT;Function=;Product=tRNA-Trp anticodon CCA;Comments=tRNA Trp anticodon CCA, Cove scores: 79.38;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	369473	369612	.	+	0	Locus=ML0288;Name=ML0288;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML0288, len: 140 bp. Possible transposase remnant, some similarity to Q9RBZ3 transposase from Pseudomonas syringae (1071 bp), (blastx scores: 51) and to Q44454|Z18270 transposase from Agrobacterium tumefaciens (1098 bp), (blastx scores: 41). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	332923	333664	.	+	0	Locus=ML0254;Name=lpqU;Function=;Product=Probable conserved lipoprotein LpqU (pseudogene);Comments=ML0254, len: 742 bp. Possible pseudogene of M. tuberculosis orthologue lpqU|Rv1022 (732 bp) (Best blastx scores: 224);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	337531	339287	.	+	0	Locus=ML0259;Name=ML0259;Function=;Product=Probable conserved transmembrane transport protein (pseudogene);Comments=ML0259, len: 1757 bp. Possible pseudogene similar to M. tuberculosis mmpL4|Rv0450c (2904 bp) (Best blastx scores: 308), also similar to ML2378 a possible orthologue of M. tuberculosis mmpL4.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	351893	352999	.	-	0	Locus=ML0268c;Name=pta;Function=;Product=Probable phosphate acetyltransferase Pta (pseudogene);Comments=ML0268c, len: 1107 bp. Possible pseudogene of M. tuberculosis orthologue pta|Rv0408 (2073 bp)  (Best blastx scores: 310).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	355303	355922	.	+	0	Locus=ML0272;Name=ML0272;Function=;Product=Probable short-chain dehydrogenase/reductase (pseudogene);Comments=ML0272, len: 620 bp. Possible short-chain dehydrogenase/reductase pseudogene. Similar to several M. tuberculosis genes e.g. Rv1941, Rv2214c, Rv2857c (Best blastx scores: 134).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	355941	356489	.	+	0	Locus=ML0273;Name=fadE7;Function=;Product=Acyl-CoA dehydrogenase FadE7 (pseudogene);Comments=ML0273, len: 549 bp. Possible pseudogene of M. tuberculosis orthologue fadE7|Rv0400c (1188 bp) (Best blastx scores: 140).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	356520	356618	.	+	0	Locus=ML0274;Name=ML0274;Function=;Product=Possible secreted protein (pseudogene);Comments=ML0274, len: 99 bp. Possible pseudogene of M. tuberculosis orthologue Rv0398c (642 bp) (Best blastx scores: 86);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	360202	360638	.	+	0	Locus=ML0277;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML0277, len: 437 bp. Possible pseudogene of M. tuberculosis orthologue PPE9|Rv0388c (543 bp) (Best blastx scores: 74);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	12194	12270	.	+	0	Locus=MLP000001;Name=ileT;Function=;Product=tRNA-Ile anticodon GAT;Comments=tRNA Ile anticodon GAT, Cove scores: 88.84;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	345708	345920	.	+	0	Locus=ML0265;Name=ML0265;Function=;Product=Hypothetical protein;Comments=ML0265, len: 70 aa. Hypothetical protein. Improbable CDS suggested by GC frameplot. Possibly the remains of a disrupted gene.;UniProt_AC=O69587;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	335129	335812	.	+	0	Locus=ML0256;Name=ML0256;Function=;Product=Possible conserved membrane protein;Comments=ML0256, len: 227 aa. Possible conserved membrane protein, highly similar to Rv1024|P96376|AL123456 hypothetical protein from M. tuberculosis (228 aa), Fasta scores: E(): 0, (70.5% identity in 220 aa overlap). Also similar to  putative membrane protein from Streptomyces coelicolor A3(2) (174 aa). Contains a hydrophobic, possible membrane-spanning region.;UniProt_AC=Q9CD41;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	614637	615000	.	-	0	Locus=ML0506c;Name=ML0506c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0506c, len: 364 bp. Possible pseudogene similar to M. tuberculosis orthologue Rv2570 (390 bp) (Best blastx scores: 169).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	364131	364909	.	+	0	Locus=ML0282;Name=ML0282;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML0282, len: 779 bp. Possible pseudogene of M. tuberculosis orthologue Rv0359 (780 bp) (Best blastx scores: 161).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	661596	662510	.	-	0	Locus=ML0545c;Name=lipH;Function=;Product=Probable lipase LipH (pseudogene);Comments=ML0545c, len: 915 bp. Possible pseudogene of M. tuberculosis orthologue lipH|Rv1399c (960 bp) (Best blastx scores: 213).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	358834	359277	.	-	0	Locus=ML0276c;Name=ML0276c;Function=;Product=Conserved hypothetical protein;Comments=ML0276c, len: 147 aa. Conserved hypothetical protein, highly similar to Rv0390|P95198|AL123456 conserved hypothetical protein from M. tuberculosis (140 aa), Fasta scores: E(): 0, (79.0% identity in 138 aa overlap). Also similar to other bacterial hypothetical proteins e.g. Q9ZCV8|AJ235272 RP600, hypothetical protein from Rickettsia prowazekii (123 aa), Fasta scores: E(): 8.6e-05, (35.1% identity in 134 aa overlap). Previously sequenced as O69593|AL023514 (147 aa), Fasta scores: E(): 0, (100.0% identity in 147 aa overlap).;UniProt_AC=O69593;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	380011	380147	.	+	0	Locus=ML0296;Name=ML0296;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0296, len: 137 bp. Possible pseudogene of M. tuberculosis orthologue Rv0421c (630 bp) (Best blastx scores: 85).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	383529	384154	.	-	0	Locus=ML0301c;Name=mutT3;Function=;Product=Possible mutator protein MutT3 (pseudogene);Comments=ML0301c, len: 626 bp. Possible pseudogene of M. tuberculosis orthologue mutT3|Rv0413 (654 bp) (Best blastx scores: 180).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	372034	372426	.	-	0	Locus=ML0291c;Name=ML0291c;Function=;Product=Hypothetical protein;Comments=ML0291c, len: 130 aa. Hypothetical unknown function. Previously sequenced as O69603|AL023514 (130 aa), Fasta scores: E(): 0, (99.2% identity in 130 aa overlap).;UniProt_AC=O69603;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	373605	373844	.	-	0	Locus=ML0292c;Name=ML0292c;Function=;Product=Hypothetical protein;Comments=ML0292c, len: 79 aa. Hypothetical unknown function. Possibly the remains of a disrupted gene.;UniProt_AC=Q9CCX2;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	375453	375662	.	-	0	Locus=ML0293c;Name=ML0293c;Function=;Product=Hypothetical protein;Comments=ML0293c, len: 69 aa. Hypothetical unknown function. Possibly the remains of a disrupted gene.;UniProt_AC=Q9CCX1;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	369817	370960	.	+	0	Locus=ML0289;Name=ML0289;Function=;Product=Putative group II intron maturase-related protein (pseudogene);Comments=ML0289, len: 1144 bp. Possible pseudogene, similar to several maturases e.g. Q9MD87|AF218567 putative maturase from Cryphonectria parasitica (Cheshnut blight fungus) (2334 bp, (blastx scores: 143); and Rv0071|O53616 Putative maturase from M. tuberculosis (705 bp), (blastx scores: 153). Belongs to the LEPREP family of dispersed repeats (see citation below);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	371225	371323	.	+	0	Locus=ML0290;Name=ML0290;Function=;Product=Possible transposase remnant (pseudogene);Comments=ML0290, len: 99 bp. Possible transposase remnant, similar to Q44454|Z18270 transposase from Agrobacterium tumefaciens (1098 bp), (blastx scores: 93); and to Q9R9U9|AJ245436 transposase tnpa1 from Pseudomonas putida (1065 bp), (blastx scores: 89). Belongs to the LEPREP family of dispersed repeats (see citation below).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	2594585	2594661	.	-	0	Locus=MLP000039;Name=pheU;Function=;Product=tRNA-Phe anticodon GAA;Comments=tRNA Phe anticodon GAA, Cove scores: 79.14;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2594797	2594869	.	-	0	Locus=MLP000041;Name=gluT;Function=;Product=tRNA-Glu anticodon TTC;Comments=tRNA Glu anticodon TTC, Cove scores: 65.04;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2594993	2595065	.	+	0	Locus=MLP000042;Name=lysT;Function=;Product=tRNA-Lys anticodon TTT;Comments=tRNA Lys anticodon TTT, Cove scores: 79.95;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	390458	391902	.	-	0	Locus=ML0305c;Name=ML0305c;Function=;Product=Possible integral membrane protein (pseudogene);Comments=ML0305c, len: 1445 bp. Possible pseudogene of M. tuberculosis orthologue Rv0537c (1434 bp) (Best blastx scores: 503);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	2769260	2769345	.	+	0	Locus=MLP000046;Name=serV;Function=;Product=tRNA-Ser anticodon GGA;Comments=tRNA Ser anticodon GGA, Cove scores: 57.12;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2949306	2949396	.	+	0	Locus=MLP000047;Name=serX;Function=;Product=tRNA-Ser anticodon CGA;Comments=tRNA Ser anticodon CGA, Cove scores: 64.30;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	477372	477956	.	+	0	Locus=ML0384;Name=sigD;Function=;Product=Probable alternative RNA polymerase sigma-D factor SigD (pseudogene);Comments=ML0384, len: 585 bp. Possible pseudogene of M. tuberculosis orthologue sigD|Rv3414c (639 bp) (Best blastx scores: 312);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	2989364	2989437	.	+	0	Locus=MLP000048;Name=glyU;Function=;Product=tRNA-Gly anticodon CCC;Comments=tRNA Gly anticodon CCC, Cove scores: 81.00;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	497358	498002	.	+	0	Locus=ML0399;Name=ML0399;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0399, len: 645 bp. Possible pseudogene of M. tuberculosis orthologue Rv3395c (615 bp) (Best blastx scores: 208);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	505778	506545	.	+	0	Locus=ML0408;Name=ML0408;Function=;Product=Possible IS1081 transposase (pseudogene);Comments=ML0408, len: 768 bp. Possible pseudogene similar to M. tuberculosis IS1081 transposase (Best blastx scores: 140);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	537010	538545	.	+	0	Locus=ML0437;Name=accA1;Function=;Product=Probable acetyl/propionyl-CoA carboxylase [alpha subunit] AccA1 (pseudogene);Comments=ML0437, len: 1536 bp. Possible pseudogene of M. tuberculosis orthologue accA1|Rv2501c (1965 bp) (Best blastx scores: 865);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	579204	579571	.	-	0	Locus=ML0477c;Name=ML0477c;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML0477c, len: 368 bp. Possible pseudogene of M. tuberculosis orthologue Rv2600 (402 bp) (Best blastx scores: 202);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	611088	612391	.	-	0	Locus=ML0504c;Name=ML0504c;Function=;Product=Transposase (pseudogene);Comments=ML0504c, len: 1304 bp. Possible pseudogene similar to transposase Q9K502 from Mycobacterium avium istA (Best blastx scores: 250).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	612561	613459	.	-	0	Locus=ML0505c;Name=ML0505c;Function=;Product=Probable transposase (pseudogene);Comments=ML0505c, len: 899 bp. Possible pseudogene similar to M. tuberculosis transposase Rv2424c (1002 bp) (Best blastx scores: 206);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	662675	663498	.	-	0	Locus=ML0546c;Name=lipI;Function=;Product=Probable lipase LipI (pseudogene);Comments=ML0546c, len: 824 bp. Possible pseudogene of M. tuberculosis orthologue lipI|Rv1400c (963 bp) (Best blastx scores: 262).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	480094	480507	.	-	0	Locus=ML0386c;Name=ML0386c;Function=;Product=Conserved hypothetical protein;Comments=ML0386c, len: 137 aa. Conserved hypothetical protein, equivalent to Rv3412|YY12_MYCTU|Q50714 conserved hypothetical protein from M. tuberculosis (136 aa), Fasta scores: E(): 0, (93.4% identity in 136 aa overlap). Also similar to Q8NSR6 Hypothetical protein Cgl0602 from Corynebacterium glutamicum (126 aa), Fasta scores: E(): 0, (42.2% identity in 116 aa overlap). Previously sequenced as YY12_MYCLE|Q49742 (137 aa), Fasta scores: E(): 0, (99.3% identity in 137 aa overlap).;UniProt_AC=Q49742;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	879313	879459	.	-	0	Locus=ML0738c;Name=pstA2;Function=;Product=Phosphate-transport integral membrane ABC transporter PstA2 (pseudogene);Comments=ML0738c, len: 147 bp. Possible pseudogene of M. tuberculosis orthologue pstA2|Rv0936 (906 bp) (Best blastx scores: 95).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	882888	883983	.	+	0	Locus=ML0742;Name=pstS2;Function=;Product=Periplasmic phosphate-binding lipoprotein PstS2 (pseudogene);Comments=ML0742, len: 1096 bp. Possible pseudogene of M. tuberculosis orthologue pstS2|Rv0932c (1113 bp) (Best blastx scores: 440).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	908397	909754	.	-	0	Locus=ML0766c;Name=ML0766c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0766c, len: 1358 bp. Possible pseudogene of M. tuberculosis orthologue Rv3254 (1389 bp) (Best blastx scores: 402).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	909847	911323	.	+	0	Locus=ML0767;Name=ML0767;Function=;Product=Possible cationic amino acid transport integral membrane protein (pseudogene);Comments=ML0767, len: 1477 bp. Possible pseudogene of M. tuberculosis orthologue Rv3253c (1488 bp) (Best blastx scores: 1109).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	160312	160401	.	+	0	Locus=MLP000004;Name=serU;Function=;Product=tRNA-Ser anticodon TGA;Comments=tRNA Ser anticodon TGA, Cove scores: 59.58;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	251305	251377	.	+	0	Locus=MLP000007;Name=alaV;Function=;Product=tRNA-Ala anticodon CGC;Comments=tRNA Ala anticodon CGC, Cove scores: 82.84;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	326132	326203	.	-	0	Locus=MLP000009;Name=glnT;Function=;Product=tRNA-Gln anticodon TTG;Comments=tRNA Gln anticodon TTG, Cove scores: 52.56;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	344340	344413	.	+	0	Locus=MLP000010;Name=leuX;Function=;Product=tRNA-Leu anticodon TAA;Comments=tRNA Leu anticodon TAA, Cove scores: 63.13;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	1316303	1316378	.	-	0	Locus=MLP000015;Name=argV;Function=;Product=tRNA-Arg anticodon CCG;Comments=tRNA Arg anticodon CCG, Cove scores: 91.71;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	1374079	1374161	.	+	0	Locus=MLP000019;Name=leuW;Function=;Product=tRNA-Leu anticodon TAG;Comments=tRNA Leu anticodon TAG, Cove scores: 55.29;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	61406	61693	.	-	0	Locus=ML0049c;Name=esxA;Function=;Product=Probable 6 kDa early secretory antigenic target homolog EsxA (ESAT-6-like protein) (L-ESAT);Comments=ML0049c, len: 95 aa. Probable esxA, 6 KDa early secretory antigenic target homolog (see citations below). Similar to Rv3875|ESA6_MYCTU|Q57165 esxA, early secretory antigenic target from M. tuberculosis (94 aa), Fasta scores: E(): 4.2e-10, (36.3% identity in 91 aa overlap). Also shows weak similarity to others e.g. CFP7_MYCTU|O53693 esxH, 10 KDa antigen from M. tuberculosis (95 aa), Fasta scores: E(): 0.17, (25.6% identity in 78 aa overlap). Other members of this family include ML0363. Previously sequenced as ESA6_MYCLE|Q50206 (95 aa), Fasta scores: E(): 0, (100.0% identity in 95 aa overlap). Belongs to the ESAT6 family. Note that previously known as esat-6.;UniProt_AC=Q50206;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	398721	399954	.	-	0	Locus=ML0312c;Name=moeA2;Function=;Product=Probable molybdenum cofactor biosynthesis protein MoeA2 (pseudogene);Comments=ML0312c, len: 1234 bp. Possible pseudogene of M. tuberculosis orthologue moeA2|Rv0438c (1218 bp) (Best blastx scores: 245). Note that previously known as moeA3.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	968481	969134	.	-	0	Locus=ML0820c;Name=lipV;Function=;Product=Probable lipase LipV (pseudogene);Comments=ML0820c, len: 654 bp. Possible pseudogene of M. tuberculosis orthologue lipV|Rv3203 (675 bp) (Best blastx scores: 236).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	1481451	1481524	.	-	0	Locus=MLP000020;Name=argW;Function=;Product=tRNA-Arg anticodon TCT;Comments=tRNA Arg anticodon TCT, Cove scores: 69.26;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	1638370	1638446	.	+	0	Locus=MLP000027;Name=proT;Function=;Product=tRNA-Pro anticodon GGG;Comments=tRNA Pro anticodon GGG, Cove scores: 80.45;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	1785017	1785093	.	-	0	Locus=MLP000028;Name=proU;Function=;Product=tRNA-Pro anticodon TGG;Comments=tRNA Pro anticodon TGG, Cove scores: 89.79;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2294807	2294883	.	-	0	Locus=MLP000036;Name=metT;Function=;Product=tRNA-Met anticodon CAT;Comments=tRNA Met anticodon CAT, Cove scores: 89.68;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2294937	2295009	.	-	0	Locus=MLP000037;Name=thrT;Function=;Product=tRNA-Thr anticodon GGT;Comments=tRNA Thr anticodon GGT, Cove scores: 79.74;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2506608	2506680	.	+	0	Locus=MLP000038;Name=argT;Function=;Product=tRNA-Arg anticodon CCT;Comments=tRNA Arg anticodon CCT, Cove scores: 73.39;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2594690	2594766	.	-	0	Locus=MLP000040;Name=aspT;Function=;Product=tRNA-Asp anticodon GTC;Comments=tRNA Asp anticodon GTC, Cove scores: 87.88;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2659699	2659773	.	+	0	Locus=MLP000043;Name=thrV;Function=;Product=tRNA-Thr anticodon TGT;Comments=tRNA Thr anticodon TGT, Cove scores: 85.47;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	tRNA	2707392	2707475	.	+	0	Locus=MLP000044;Name=tyrT;Function=;Product=tRNA-Tyr anticodon GTA;Comments=tRNA Tyr anticodon GTA, Cove scores: 59.73;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	323092	323406	.	-	0	Locus=ML0247c;Name=arsC;Function=Reduction of arsenate [AS(V)] to arsenite [AS(III)]. this protein expands the substrate specificity of arsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [Catalytic activity: Arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin].;Product=Possible arsenate reductase ArsC;Comments=ML0247c, len: 104 aa. Possible arsC, arsenate reductase, similar to several others e.g. ARC1_ECOLI|P08692 arsC, arsenate reductase from Escherichia coli (141 aa), Fasta scores: E(): 1.7e-07, (38.8% identity in 103 aa overlap).;UniProt_AC=Q9CD46;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	264898	265101	.	+	0	Locus=ML0198;Name=cspA;Function=;Product=Probable cold shock protein A CspA;Comments=ML0198, len: 67 aa. Probable cspA, cold shock protein A, identical to Rv3648c|CSPA_MYCTU|O06360 probable cspA, cold shock protein A from M. tuberculosis (67 aa), Fasta scores: E(): 3.9e-27, (97.0% identity in 67 aa overlap). Similar to many others e.g.  CSP_ARTGO|P54584 csp, cold shock protein from Arthrobacter globiformis (67 aa), Fasta scores: E(): 8.8e-19, (71.6% identity in 67 aa overlap). Previously sequenced as O69550|AL023093 (67 aa), Fasta scores: E(): 1.2e-27, (100.0% identity in 67 aa overlap). Also similar to ML2147 from M. leprae. Contains Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain. Contains PS00352 'Cold-shock' DNA-binding domain signature.;UniProt_AC=O69550;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	1	1566	.	+	0	Locus=ML0001;Name=dnaA;Function=Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (DNAA BOX): 5'-TTATC(C/A)A(C/A)A-3'. DNAA binds to ATP and to acidic phospholipids.;Product=Probable chromosomal replication initiator protein DnaA;Comments=ML0001, len: 521 aa. Probable dnaA, chromosomal replication initiator protein (see citations below), highly similar to other Mycobacterial chromosomal replication initiator proteins e.g. Rv0001|DNAA_MYCTU|P49993 from M. tuberculosis (507 aa), Fasta scores: E(): 0, (87.2% identity in 507 aa overlap); and DNAA_MYCSM|P49992 from M. smegmatis (495 aa), Fasta scores: E(): 0, (69.2% identity in 441 aa overlap). Previously sequenced as DNAA_MYCLE|P46388 (521 aa), Fasta scores: E(): 0, (99.8% identity in 521 aa overlap). Contains Pfam match to entry PF00308 bac_dnaA, Bacterial dnaA protein. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS01008 DnaA protein signature. Belongs to the DnaA family. Note that the first base of this gene has been taken as base 1 of the Mycobacterium leprae genomic sequence.;UniProt_AC=P46388;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	976029	977055	.	+	0	Locus=ML0823;Name=ML0823;Function=;Product=Possible transmembrane cation transporter (pseudogene);Comments=ML0823, len: 1027 bp. Possible pseudogene of M. tuberculosis orthologue Rv3200c (1068 bp) (Best blastx scores: 571).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	tRNA	2736804	2736877	.	+	0	Locus=MLP000045;Name=proY;Function=;Product=tRNA-Pro anticodon CGG;Comments=tRNA Pro anticodon CGG, Cove scores: 75.56;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	392397	393160	.	+	0	Locus=ML0306;Name=ML0306;Function=;Product=Possible conserved membrane protein (pseudogene);Comments=ML0306, len: 764 bp. Possible pseudogene of M. tuberculosis orthologue Rv0538 (1647 bp) (Best blastx scores: 184);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	393501	393921	.	+	0	Locus=ML0307;Name=ML0307;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0307, len: 421 bp. Possible pseudogene of M. tuberculosis orthologue Rv0434 (654 bp) (Best blastx scores: 130);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	395182	397023	.	-	0	Locus=ML0309c;Name=ML0309c;Function=;Product=Putative conserved ATPase (pseudogene);Comments=ML0309c, len: 1842 bp. Possible pseudogene of M. tuberculosis orthologue Rv0435c (2187 bp) (Best blastx scores: 329);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	333751	335094	.	+	0	Locus=ML0255;Name=eno;Function=;Product=Probable enolase Eno (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase);Comments=ML0255, len: 447 aa. Probable eno, enolase (EC 4.2.1.11), highly similar to Rv1023|ENO_MYCTU|P96377 eno, probable enolase from M. tuberculosis  (429 aa), Fasta scores: E(): 0, (88.8% identity in 429 aa overlap). Similar to many others e.g. ENO_BACSU|P37869 eno, enolase (2-phosphoglycerate dehydratase) from Bacillus subtilis (430 aa), Fasta scores: E(): 0, (58.8% identity in 425 aa overlap). Contains Pfam match to entry PF00113 enolase, Enol-ase. Contains PS00164 Enolase signature. Magnesium is required for catalysis and for stabilizing the dimer. Belongs to the enolase family.;UniProt_AC=Q9CD42;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	456419	456733	.	+	0	Locus=ML0363;Name=esxT;Function=;Product=PUTATIVE ESAT-6 LIKE PROTEIN ESXT;Comments=ML0363, len: 104 aa. Possible esxT, Esat-6 like protein. Similar to M. tuberculosis Rv3444c, esat6-family protein, TR:O06261 (EMBL:Al123456) (100 aa), Fasta scores: E(): 3.3e-20, 71.2% identity in 73 aa overlap and others of the esat6 family e.g. esat6 itself, 6 kDa early secretory antigenic target, SW:ESA6_MYCTU (Q57165) (94 aa), Fasta scores: E(): 1.5, 28.4% identity in 67 aa overlap.;UniProt_AC=Q9CCV7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1473958	1475002	.	+	0	Locus=ML1236;Name=pks11;Function=;Product=Possible chalcone synthase Pks11 (pseudogene);Comments=ML1236, len: 1045 bp. Possible pseudogene of M. tuberculosis orthologue pks11|Rv1665 (1062 bp) (Best blastx scores: 356).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	539671	540205	.	+	0	Locus=ML0439;Name=ML0439;Function=;Product=Possible oxidase regulatory-related protein (pseudogene);Comments=ML0439, len: 535 bp. Possible pseudogene of M. tuberculosis orthologue Rv2499c (558 bp) (Best blastx scores: 164);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	540205	540783	.	+	0	Locus=ML0440;Name=citE;Function=;Product=Probable citrate (pro-3S) lyase [beta subunit] CitE (pseudogene);Comments=ML0440, len: 579 bp. Possible pseudogene of M. tuberculosis orthologue citE|Rv2498c (822 bp) (Best blastx scores: 389);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	324556	326034	.	-	0	Locus=ML0249c;Name=glmU;Function=;Product=Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU;Comments=ML0249c, len: 492 aa. Probable glmU, UDP-n-acetylglucosamine pyrophosphorylase (EC 2.7.7.23), highly similar to Rv1018c|P96382|AL123456 glmU, probable UDP-N-acetylglucosamine pyrophosphorylase from M. tuberculosis (495 aa), Fasta scores: E(): 0, (82.1% identity in 492 aa overlap). Similar to many others e.g. GLMU_NEIGO|Q50986 glmU, UDP-N-acetylglucosamine pyrophosphorylase from Neisseria gonorrhoeae (456 aa), Fasta scores: E(): 0, (37.4% identity in 462 aa overlap). Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase. Contains 5 Pfam matches to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats).;UniProt_AC=Q9CD44;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1522332	1523603	.	+	0	Locus=ML1279;Name=ML1279;Function=;Product=Conserved membrane protein (pseudogene);Comments=ML1279, len: 1272 bp. Possible pseudogene of M. tuberculosis orthologue Rv1619 (1455 bp) (Best blastx scores: 351).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	149361	150125	.	-	0	Locus=ML0108c;Name=ML0108c;Function=;Product=Probable short-chain type dehydrogenase/reductase;Comments=ML0108c, len: 254 aa. Probable short-chain dehydrogenase/reductase (EC 1.-.-.-), highly similar to Rv3791|Y1J1_MYCTU|P72057 short-chain dehydrogenase/reductase from M. tuberculosis (254 aa), Fasta scores: E(): 0, (89.0% identity in 254 aa overlap); and to other Mycobacterial putative oxidoreductases. Also similar to Q9KZA5 putative short-chain dehydrogenase from Streptomyces coelicolor A3(2) (256 aa), Fasta scores: E(): 3.2e-41, (44.8% identity in 254 aa overlap). Shows weaker similarity to PHBB_ALCEU|P14697 phbB, acetoacetyl-CoA reductase from Alcaligenes eutrophus (246 aa), Fasta scores: E(): 3e-09, (28.3% identity in 191 aa overlap). Also shows weak similarity to ML0429 and to the C-terminal half of ML2565 from M. leprae. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature. Belongs to the short-chain dehydrogenase/reductase (SDR) family.;UniProt_AC=Q9CDA5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	250221	251249	.	+	0	Locus=ML0185;Name=ML0185;Function=;Product=Probable conserved transmembrane protein;Comments=ML0185, len: 342 aa. Probable conserved transmembrane protein, highly similar to Rv0996|O05579|AL123456 conserved transmembrane protein from M.tuberculosis (358 aa), Fasta scores: E(): 0, (66.4% identity in 360 aa overlap). Previously sequenced as Q9Z5F8|AL035500 (342 aa), Fasta scores: E(): 0, (100.0% identity in 342 aa overlap). Contains possible signal sequence and other hydrophobic domains.;UniProt_AC=Q9Z5F8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	450364	451274	.	-	0	Locus=ML0356c;Name=fadE27;Function=;Product=Probable acyl-CoA dehydrogenase FadE27 (pseudogene);Comments=ML0356c, len: 911 bp. Possible pseudogene of M. tuberculosis orthologue fadE27|Rv3505 (1122 bp) (Best blastx scores: 223);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	452647	452817	.	+	0	Locus=ML0358;Name=fdxD;Function=;Product=Probable ferredoxin FdxD (pseudogene);Comments=ML0358, len: 171 bp. Possible pseudogene of M. tuberculosis orthologue fdxD|Rv3503c (192 bp) (Best blastx scores: 212);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	452940	453842	.	+	0	Locus=ML0359;Name=ML0359;Function=;Product=Probable short-chain dehydrogenase/reductase (pseudogene);Comments=ML0359, len: 903 bp. Possible pseudogene of M. tuberculosis orthologue Rv3502c (954 bp) (Best blastx scores: 300);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	414866	415129	.	+	0	Locus=ML0325;Name=ML0325;Function=;Product=hypothetical protein;Comments=ML0325, len: 87 aa. hypothetical protein. Possibly the remains of a disrupted gene.;UniProt_AC=Q9CCW3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	299138	300436	.	+	0	Locus=ML0228;Name=ML0228;Function=;Product=Probable conserved transmembrane protein rich in alanine, arginine and proline;Comments=ML0228, len: 432 aa. Probable conserved ala-, arg-, pro-rich transmembrane protein, similar to Rv3604c|O06278|AL123456  ala-, arg-, pro-rich transmembrane protein from M. tuberculosis (397 aa), Fasta scores: E(): 0, (59.7% identity in 432 aa overlap). Previously sequenced as O69526|AL023093 (432 aa), Fasta scores: E(): 0, (100.0% identity in 432 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=O69526;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	451303	452425	.	-	0	Locus=ML0357c;Name=fadE26;Function=;Product=Probable acyl-CoA dehydrogenase FadE26 (pseudogene);Comments=ML0357c, len: 1123 bp. Possible pseudogene of M. tuberculosis orthologue fadE26|Rv3504 (1203 bp) (Best blastx scores: 551);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	454076	454786	.	+	0	Locus=ML0360;Name=yrbE4A;Function=;Product=Conserved hypothetical unknown integral membrane protein, part of mce4 operon YrbE4A (pseudogene);Comments=ML0360, len: 711 bp. Possible pseudogene of M. tuberculosis orthologue Rv3501c|yrbE4A (765 bp) (Best blastx scores: 493);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1121896	1122135	.	+	0	Locus=ML0953;Name=ML0953;Function=;Product=hypothetical protein;Comments=ML0953, len: 79 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCC9;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	211150	212814	.	-	0	Locus=ML0150c;Name=pgi;Function=;Product=Probable glucose-6-phosphate isomerase Pgi (phosphoglucose isomerase) (phosphohexose isomerase) (PHI);Comments=ML0150c, len: 554 aa. Probable pgi, glucose-6-phosphate isomerase (EC 5.3.1.9), highly similar to Rv0946c|G6PI_MYCTU|P77895 pgi, glucose-6-phosphate isomerase from M. tuberculosis (553 aa), Fasta scores: E(): 0, (85.5% identity in 552 aa overlap); and to G6PI_MYCSM|P96803 pgi, glucose-6-phosphate isomerase from Mycobacterium smegmatis (442 aa), Fasta scores: E(): 0, (84.1% identity in 440 aa overlap). Contains Pfam match to entry PF00342 PGI, Phosphoglucose isomerase. Contains PS00765 Phosphoglucose isomerase signature 1. Contains PS00174 Phosphoglucose isomerase signature 2. Belongs to the GPI family.;UniProt_AC=Q9CD75;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	224616	226199	.	+	0	Locus=ML0161;Name=purH;Function=Involved in de novo purine biosynthesis (at the ninth and tenth steps) [Catalytiv activity 1: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide] [Catalytiv activity 2: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide].;Product=Probable bifunctional purine biosynthesis protein PurH : phosphoribosylaminoimidazolecarboxamide formyltransferase (aicar transformylase) and inosinemonophosphatecyclohydrolase (IMP cyclohydrolase) (inosinicase) (IMP synthetase) (ATIC);Comments=ML0161, len: 527 aa. Probable purH, bifunctional purine biosynthesis protein including 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase (EC 2.1.2.3) and inosine-monophosphate (IMP) cyclohydrolase (EC 3.5.4.10), highly similar to Rv0957|PUR9_MYCTU|P71553 purH from (523 aa), Fasta scores: E(): 0, (88.1% identity in 520 aa overlap). Similar to many e.g. PUR9_BACSU|P12048 purN, phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase from Bacillus subtilis (512 aa), Fasta scores: E(): 0, (43.2% identity in 519 aa overlap). Previously sequenced as PUR9_MYCLE|Q9Z5H5 (527 aa), Fasta scores: E(): 0, (100.0% identity in 527 aa overlap). Contains Pfam match to entry PF01808 AICARFT_IMPCHas, AICARFT/IMPCHase bienzyme. Belongs to the PurH family.;UniProt_AC=Q9Z5H5;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	485790	486125	.	+	0	Locus=ML0391;Name=ML0391;Function=;Product=Possible transcriptional regulator (pseudogene);Comments=ML0391, len: 336 bp. Possible pseudogene of M. tuberculosis orthologue Rv3405c (567 bp) (Best blastx scores: 162);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	400043	400676	.	-	0	Locus=ML0313c;Name=ML0313c;Function=;Product=Probable dehydrogenase/reductase (pseudogene);Comments=ML0313c, len: 634 bp. Possible pseudogene of M. tuberculosis orthologue Rv0439c (936 bp) (Best blastx scores: 248);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	408188	409346	.	-	0	Locus=ML0318c;Name=radA;Function=;Product=Probable DNA repair protein RadA (pseudogene);Comments=ML0318c, len: 1159 bp. Possible pseudogene of M. tuberculosis orthologue radA|Rv3585 (1443 bp)  (Best blastx scores: 221);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	540803	541461	.	+	0	Locus=ML0441;Name=pdhA;Function=;Product=Probable pyruvate dehydrogenase E1 component [alpha subunit] PdhA (pseudogene);Comments=ML0441, len: 659 bp. Possible pseudogene of M. tuberculosis orthologue pdhA|Rv2497c (1104 bp) (Best blastx scores: 325);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1431583	1432440	.	-	0	Locus=ML1211c;Name=treY;Function=;Product=Maltooligosyltrehalose synthase TreY (pseudogene);Comments=ML1211c, len: 858 bp. Possible pseudogene of M. tuberculosis orthologue treY|Rv1563c  (2298 bp) (Best blastx scores: 368).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	416570	416846	.	-	0	Locus=ML0326c;Name=esxR;Function=;Product=Low molecular weight protein antigen EsxR (pseudogene);Comments=ML0326c, len: 277 bp. Possible pseudogene of M. tuberculosis orthologue Rv3019c|esxR (291 bp) (Best blastx scores: 118);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	416867	417153	.	-	0	Locus=ML0327c;Name=esxS;Function=;Product=Conserved hypothetical protein EsxS (pseudogene);Comments=ML0327c, len: 287 bp. Possible pseudogene of M. tuberculosis orthologue Rv3020c|esxS (294 bp) (Best blastx scores: 124).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	417243	418419	.	-	0	Locus=ML0328c;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML0328c, len: 1177 bp. Possible pseudogene of M. tuberculosis orthologue Rv3021c|PPE47 (1077 bp)  (Best blastx scores: 169).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	420550	420877	.	-	0	Locus=ML0329c;Name=ML0329c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0329c, len: 328 bp. Possible pseudogene of M. tuberculosis orthologue Rv1942c (330 bp) (Best blastx scores: 168);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	420877	420990	.	-	0	Locus=ML0330c;Name=ML0330c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0330c, len: 114 bp. Possible pseudogene of M. tuberculosis orthologue Rv1943c (378 bp) (Best blastx scores: 154);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	421106	422311	.	-	0	Locus=ML0331c;Name=arsB2;Function=;Product=Possible arsenical pump integral membrane protein ArsB2 (pseudogene);Comments=ML0331c, len: 1206 bp. Possible pseudogene of M. tuberculosis orthologue arsB2|Rv3578 (1242 bp) (Best blastx scores: 423);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	422318	423056	.	-	0	Locus=ML0332c;Name=ML0332c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0332c, len: 739 bp. Possible pseudogene of M. tuberculosis orthologue Rv3577 (867 bp) (Best blastx scores: 257).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	424107	424679	.	-	0	Locus=ML0334c;Name=lppH;Function=;Product=Possible conserved lipoprotein LppH (pseudogene);Comments=ML0334c, len: 573 bp. Possible pseudogene of M. tuberculosis orthologue lppH|Rv3576 (714 bp) (Best blastx scores: 216). Note that previously known as pknM.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	427652	428676	.	+	0	Locus=ML0338;Name=ML0338;Function=;Product=Transcriptional regulatory protein (probably LacI family) (pseudogene);Comments=ML0338, len: 1025 bp. Possible pseudogene similar to M. tuberculosis orthologue Rv3575c (1080 bp) (Best blastx scores: 220);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	428888	429250	.	-	0	Locus=ML0339c;Name=ML0339c;Function=;Product=Transcriptional regulatory protein (probably TetR-family) (pseudogene);Comments=ML0339c, len: 363 bp. Possible pseudogene of M. tuberculosis orthologue Rv3574 (600 bp) (Best blastx scores: 269);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1010013	1011177	.	+	0	Locus=ML0850;Name=ltp1;Function=;Product=Probable lipid-transfer protein Ltp1 (pseudogene);Comments=ML0850, len: 1165 bp. Possible pseudogene of M. tuberculosis orthologue ltp1|Rv2790c (1206 bp) (Best blastx scores: 347).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	409443	409994	.	-	0	Locus=ML0319c;Name=lpqE;Function=;Product=Possible lipoprotein LpqE;Comments=ML0319c, len: 183 aa. Possible lpqE, conserved lipoprotein, highly similar to Rv3584|O53569|AL123456 lpqE, conserved lipoprotein from M. tuberculosis (182 aa), Fasta scores: E(): 0, (63.4% identity in 175 aa overlap). Previously sequenced as Q9ZBM7|AL035159 (183 aa), Fasta scores: E(): 0, (99.5% identity in 183 aa overlap). Contains a probable N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=Q9ZBM7;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	429654	431496	.	+	0	Locus=ML0340;Name=fadE34;Function=;Product=Probable acyl-CoA dehydrogenase FadE34 (pseudogene);Comments=ML0340, len: 1843 bp. Possible pseudogene of M. tuberculosis orthologue fadE34|Rv3573c (2136 bp) (Best blastx scores: 539);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	431728	432219	.	-	0	Locus=ML0341c;Name=ML0341c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0341c, len: 492 bp. Possible pseudogene of M. tuberculosis orthologue Rv3572 (531 bp) (Best blastx scores: 324);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	432324	433324	.	-	0	Locus=ML0342c;Name=hmp;Function=;Product=Possible hemoglobine-related protein Hmp (pseudogene);Comments=ML0342c, len: 1001 bp. Possible pseudogene of M. tuberculosis orthologue Rv3571|hmp (1077 bp) (Best blastx scores: 484);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	434747	435271	.	+	0	Locus=ML0344;Name=bphD;Function=;Product=Probable 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD (pseudogene);Comments=ML0344, len: 525 bp. Possible pseudogene of M. tuberculosis orthologue Rv3569c|bphD (876 bp) (Best blastx scores: 339);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	435603	436742	.	-	0	Locus=ML0345c;Name=ltp3;Function=;Product=Probable lipid carrier protein or keto acyl-CoA thiolase Ltp3 (pseudogene);Comments=ML0345c, len: 1140 bp. Possible pseudogene of M. tuberculosis orthologue Rv3523|ltp3 (1185 bp) (Best blastx scores: 319);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	436784	437195	.	-	0	Locus=ML0346c;Name=ltp4;Function=;Product=Possible lipid transfer protein or keto acyl-CoA thiolase Ltp4 (pseudogene);Comments=ML0346c, len: 412 bp. Possible pseudogene of M. tuberculosis orthologue Rv3522|ltp4 (1065 bp) (Best blastx scores: 167);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	437392	437982	.	-	0	Locus=ML0347c;Name=ML0347c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0347c, len: 591 bp. Possible pseudogene of M. tuberculosis orthologue Rv3521 (912 bp) (Best blastx scores: 236);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	439394	439705	.	-	0	Locus=ML0349c;Name=ML0349c;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0349c, len: 312 bp. Possible pseudogene of M. tuberculosis orthologue Rv3519 (711 bp) (Best blastx scores: 156);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	442416	443186	.	-	0	Locus=ML0350c;Name=ML0350c;Function=;Product=Possible transferase (pseudogene);Comments=ML0350c, len: 771 bp. Possible pseudogene similar to M. tuberculosis Rv3729 (2331 bp) (Best blastx scores: 294);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	444088	444738	.	-	0	Locus=ML0351c;Name=echA19;Function=;Product=Possible enoyl-CoA hydratase EchA19 (pseudogene);Comments=ML0351c, len: 651 bp. Possible pseudogene of M. tuberculosis orthologue echA19|Rv3516 (792 bp) (Best blastx scores: 238);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	444861	445796	.	+	0	Locus=ML0352;Name=fadD19;Function=;Product=Probable fatty-acid-CoA synthetase FadD19 (pseudogene);Comments=ML0352, len: 936 bp. Possible pseudogene of M. tuberculosis orthologue fadD19|Rv3515c (1647 bp) (Best blastx scores: 221);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	446610	447406	.	+	0	Locus=ML0353;Name=ML0353;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0353, len: 797 bp. Possible pseudogene of M. tuberculosis orthologue Rv3510c (837 bp) (Best blastx scores: 461);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	449016	450184	.	-	0	Locus=ML0355c;Name=fadD17;Function=;Product=Possible fatty-acid-CoA synthase FadD17 (pseudogene);Comments=ML0355c, len: 1169 bp. Possible pseudogene of M. tuberculosis orthologue fadD17|Rv3506 (1509 bp) (Best blastx scores: 515);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2615455	2615694	.	-	0	Locus=ML2201c;Name=ML2201c;Function=;Product=hypothetical protein;Comments=ML2201c, len: 79 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBC5;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	454841	455650	.	+	0	Locus=ML0361;Name=yrbE4B;Function=;Product=Conserved hypothetical unknown integral membrane protein, part of mce4 operon YrbE4B (pseudogene);Comments=ML0361, len: 810 bp. Possible pseudogene of M. tuberculosis orthologue Rv3500c|yrbE4B (843 bp) (Best blastx scores: 393);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	455771	456329	.	+	0	Locus=ML0362;Name=mce4A;Function=;Product=Mce-family protein Mce4A (pseudogene);Comments=ML0362, len: 559 bp. Possible pseudogene of M. tuberculosis orthologue mce4A|Rv3499c (1203 bp) (Best blastx scores: 195);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	459448	459649	.	+	0	Locus=ML0367;Name=ML0367;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0367, len: 202 bp. Possible pseudogene of M. tuberculosis orthologue Rv3440c (312 bp) (Best blastx scores: 104);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	459676	460545	.	+	0	Locus=ML0368;Name=ML0368;Function=;Product=Conserved hypothetical alanine and proline rich protein (pseudogene);Comments=ML0368, len: 870 bp. Possible pseudogene of M. tuberculosis orthologue Rv3439c (1404 bp) (Best blastx scores: 221);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	464952	465074	.	-	0	Locus=ML0372c;Name=ML0372c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0372c, len: 123 bp. Possible pseudogene similar to several M. tuberculosis conserved hypothetical proteins e.g. Rv3399 (1047 bp), Rv1729, Rv1889c and Rv0893c etc (Best blastx scores: 137).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	466654	468023	.	+	0	Locus=ML0374;Name=gadB;Function=;Product=Probable glutamate decarboxylase GadB (pseudogene);Comments=ML0374, len: 1370 bp. Possible pseudogene of M. tuberculosis orthologue gadB|Rv3432c (1383 bp) (Best blastx scores: 527);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	541507	542533	.	+	0	Locus=ML0442;Name=pdhB;Function=;Product=Probable pyruvate dehydrogenase E1 component [beta subunit] PdhB (pseudogene);Comments=ML0442, len: 1027 bp. Possible pseudogene of M. tuberculosis orthologue pdhB|Rv2496c (1047 bp) (Best blastx scores: 387);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	542562	543750	.	+	0	Locus=ML0443;Name=pdhC;Function=;Product=Probable dihydrolipoamide S-acetyltransferase E2 component PdhC (pseudogene);Comments=ML0443, len: 1189 bp. Possible pseudogene of M. tuberculosis orthologue pdhC|Rv2495c (1182 bp) (Best blastx scores: 324);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	500827	501748	.	-	0	Locus=ML0403c;Name=iunH;Function=;Product=Probable nucleoside hydrolase IunH (pseudogene);Comments=ML0403c, len: 922 bp. Possible pseudogene of M. tuberculosis orthologue iunH|Rv3393 (927 bp) (Best blastx scores: 213);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	501851	502404	.	+	0	Locus=ML0404;Name=cmaA1;Function=;Product=Cyclopropane mycolic acid synthase 1 CmaA1 (pseudogene);Comments=ML0404, len: 554 bp. Possible pseudogene of M. tuberculosis orthologue cmaA1|Rv3392c (864 bp)  (Best blastx scores: 278);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	457425	457886	.	+	0	Locus=ML0365;Name=rpsI;Function=;Product=Probable 30S ribosomal protein S9 RpsI;Comments=ML0365, len: 153 aa. Probable rpsI, ribosomal protein S9, highly similar to Rv3442c|RS9_MYCTU|O06259 rpsI, 30S ribosomal protein S9 from M. tuberculosis (151 aa), Fasta scores: E(): 0, (83.2% identity in 155 aa overlap). Also highly similar to others e.g. Q53875|RS9_STRCO|SC6G4.13 from Streptomyces coelicolor (170 aa). Previously sequenced as RS9_MYCLE|P40828 (153 aa), Fasta scores: E(): 0, (99.3% identity in 153 aa overlap). Contains Pfam match to entry PF00380 Ribosomal_S9, Ribosomal protein S9/S16. Contains PS00360 Ribosomal protein S9 signature. Belongs to the S9P family of ribosomal proteins.;UniProt_AC=P40828;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	477952	478699	.	+	0	Locus=ML0385;Name=ML0385;Function=;Product=Hypothetical alanine and proline rich protein (pseudogene);Comments=ML0385, len: 748 bp. Possible pseudogene of M. tuberculosis orthologue Rv3413c (900 bp) (Best blastx scores: 318);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	485209	485601	.	-	0	Locus=ML0390c;Name=ML0390c;Function=;Product=Probable dioxygenase (pseudogene);Comments=ML0390c, len: 393 bp. Possible pseudogene of M. tuberculosis orthologue Rv3406 (888 bp) (Best blastx scores: 382);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	580138	580326	.	-	0	Locus=ML0479c;Name=ML0479c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0479c, len: 189 bp. Possible pseudogene of M. tuberculosis orthologue Rv2598 (495 bp) (Best blastx scores: 204).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	580454	581051	.	-	0	Locus=ML0480c;Name=ML0480c;Function=;Product=Probable membrane protein (pseudogene);Comments=ML0480c, len: 598 bp. Possible pseudogene of M. tuberculosis orthologue Rv2597 (621 bp) (Best blastx scores: 175).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	469289	470290	.	+	0	Locus=ML0376;Name=ML0376;Function=;Product=Possible membrane protein;Comments=ML0376, len: 333 aa. Possible membrane protein. Some similarity with O86787 putative lipase from Streptomyces coelicolor A3(2) (420 aa), Fasta scores: E(): 0, (29.0% identity in 286 aa overlap). Contains hydrophobic, possible membrane-spanning region near the N-terminus.;UniProt_AC=Q9CCV4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	471841	472896	.	+	0	Locus=ML0379;Name=gcp;Function=;Product=Probable O-sialoglycoprotein endopeptidase Gcp (Glycoprotease);Comments=ML0379, len: 351 aa. Probable gcp, glycoprotease (EC 3.4.24.57), highly similar to Rv3419c|GCP_MYCTU|Q50709 gcp, probable O-sialoglycoprotein endopeptidase from M. tuberculosis (344 aa), Fasta scores: E(): 0, (86.1% identity in 345 aa overlap). Similar to other O-sialoglycoprotein endopeptidases e.g. GCP_PASHA|P36175 from Pasteurella haemolytica (325 aa), Fasta scores: E(): 0, (45.8% identity in 319 aa overlap); and O86793|GCP_STRCO|SC6G4.30 from Streptomyces coelicolor (374 aa). Previously sequenced as GCP_MYCLE|P37969 (351 aa), Fasta scores: E(): 0, (100.0% identity in 351 aa overlap). Contains Pfam match to entry PF00814 Peptidase_M22, Glycoprotease family. Contains PS01016 Glycoprotease family signature. Belongs to the Peptidase family M22; also known as the Glycoprotease family.;UniProt_AC=P37969;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	544152	545200	.	-	0	Locus=ML0444c;Name=ML0444c;Function=;Product=Possible group II intron maturase (pseudogene);Comments=ML0444c, len: 1049 bp. Possible pseudogene similar to M. tuberculosis Rv0071 (708 bp) (Best blastx scores: 239);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	498083	499158	.	+	0	Locus=ML0400;Name=ML0400;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0400, len: 1076 bp. Possible pseudogene of M. tuberculosis orthologue Rv3394c (1584 bp) (Best blastx scores: 268);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	499304	499756	.	-	0	Locus=ML0401c;Name=ML0401c;Function=;Product=Probable phosphate transport system transcriptional regulatory protein PhoY2 (pseudogene);Comments=ML0401c, len: 453 bp. Possible pseudogene similar to M. tuberculosis phoY2|Rv0821c (642 bp) (Best blastx scores: 152) also similar to ML2188 a possible orthologue of M. tuberculosis phoY2.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	499942	500373	.	-	0	Locus=ML0402c;Name=ML0402c;Function=;Product=Probable serine esterase, cutinase family (pseudogene);Comments=ML0402c, len: 432 bp. Possible pseudogene similar to M. tuberculosis Rv1758|cut1 (525 bp) (Best blastx scores: 151);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	491044	492633	.	+	0	Locus=ML0395;Name=guaA;Function=;Product=Probable GMP synthase [glutamine-hydrolyzing] GuaA (Glutamine amidotransferase) (GMP synthetase) ;Comments=ML0395, len: 529 aa. Probable guaA, gmp synthase (EC 6.3.5.2) (see citation below), highly similar to Rv3396c|GUAA_MYCTU|Q50729 guaA, GMP synthase from M. tuberculosis  (525 aa), Fasta scores: E(): 0, (86.9% identity in 525 aa overlap). Also similar to others e.g. GUAA_BACSU|P29727 guaA, GMP synthase [glutamine-hydrolyzing] from Bacillus subtilis (513 aa), Fasta scores: E(): 0, (50.7% identity in 515 aa overlap); and Q9L0H2|GUAA_STRCO from Streptomyces coelicolor (526 aa). Previously sequenced as GUAA_MYCLE|P46810 (590 aa), Fasta scores: E(): 0, (100.0% identity in 529 aa overlap). Contains Pfam match to entry PF00958 GMP_synt_C, GMP synthase C terminal domain. Contains Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I. Contains PS00442 Glutamine amidotransferases class-I active site. Belongs to the type-1 glutamine amidotransferase family in the N-terminal section. And belongs to the GMP synthase family in the C-terminal section.;UniProt_AC=P46810;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	506862	507533	.	-	0	Locus=ML0409c;Name=ML0409c;Function=;Product=Possible IS6110 transposase (pseudogene);Comments=ML0409c, len: 672 bp. Possible pseudogene similar to M. tuberculosis IS6110 transposase (Best blastx scores: 164);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	510370	510982	.	-	0	Locus=ML0412c;Name=lpqD;Function=;Product=Probable conserved lipoprotein LpqD (pseudogene);Comments=ML0412c, len: 613 bp. Possible pseudogene of M. tuberculosis orthologue lpqD|Rv3390 (711 bp)  (Best blastx scores: 254);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	513500	514619	.	-	0	Locus=ML0415c;Name=ML0415c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0415c, len: 1120 bp. Possible pseudogene of M. tuberculosis orthologue Rv3371 (1341 bp) (Best blastx scores: 169);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	514920	517124	.	+	0	Locus=ML0416;Name=dnaE2;Function=;Product=DNA polymerase III [alpha chain] DnaE2 (pseudogene);Comments=ML0416, len: 2205 bp. Possible pseudogene of M. tuberculosis orthologue dnaE2|Rv3370c (3240 bp) (Best blastx scores: 538);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	517300	517584	.	-	0	Locus=ML0417c;Name=ML0417c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0417c, len: 285 bp. Possible pseudogene of M. tuberculosis orthologue Rv3369 (435 bp) (Best blastx scores: 151);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	546028	546565	.	-	0	Locus=ML0445c;Name=ML0445c;Function=;Product=REP-family protein (pseudogene);Comments=ML0445c, len: 538 bp. Possible pseudogene similar to M. tuberculosis REP-family protein, similar to Rv1128c, Rv1702, Rv3466 etc (Best blastx scores: 218).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	546689	547133	.	-	0	Locus=ML0446c;Name=echA14;Function=;Product=Probable enoyl-CoA hydratase EchA14 (pseudogene);Comments=ML0446c, len: 445 bp. Possible pseudogene similar to M. tuberculosis orthologue echA14|Rv2486 (771 bp) (Best blastx scores: 194);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	519276	521680	.	+	0	Locus=ML0420;Name=ML0420;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0420, 2405 bp. Possible pseudogene of M. tuberculosis orthologue Rv3365c (2631 bp) (Best blastx scores: 540);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	521735	522127	.	+	0	Locus=ML0421;Name=ML0421;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0421, len: 393 bp. Possible pseudogene of M. tuberculosis orthologue Rv3364c (393 bp) (Best blastx scores: 181);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	522248	522814	.	+	0	Locus=ML0422;Name=ML0422;Function=;Product=Probable ATP/GTP-binding protein (pseudogene);Comments=ML0422, len: 567 bp. Possible pseudogene of M. tuberculosis orthologue Rv3362c (582 bp) (Best blastx scores: 425);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	522865	523112	.	+	0	Locus=ML0423;Name=ML0423;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0423, len: 248 bp. Possible pseudogene of M. tuberculosis orthologue Rv3361c (552 bp) (Best blastx scores: 162);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	527083	528558	.	+	0	Locus=ML0428;Name=ML0428;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0428, len: 1476 bp. Possible pseudogene of M. tuberculosis orthologue Rv2510c (1602 bp) (Best blastx scores: 399);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1352048	1352331	.	+	0	Locus=ML1156;Name=ML1156;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1156, len: 284 bp. Possible pseudogene of M. tuberculosis orthologue Rv1322 (297 bp) (Best blastx scores: 222).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	531815	532465	.	-	0	Locus=ML0432c;Name=ML0432c;Function=;Product=Probable transcriptional regulatory protein (TetR-family) (pseudogene);Comments=ML0432c, len: 651 bp. Possible pseudogene of M. tuberculosis orthologue Rv2506 (648 bp) (Best blastx scores: 173);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	532615	533913	.	+	0	Locus=ML0433;Name=fadD35;Function=;Product=Probable fatty-acid-CoA synthase FadD35 (pseudogene);Comments=ML0433, len: 1299 bp. Possible pseudogene of M. tuberculosis orthologue fadD35|Rv2505c (1644 bp) (Best blastx scores: 403);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	534034	534711	.	+	0	Locus=ML0434;Name=scoA;Function=;Product=Probable succinyl-CoA:3-ketoacid-Coenzyme A transferase [alpha subunit] ScoA (pseudogene);Comments=ML0434, len: 678 bp. Possible pseudogene of M. tuberculosis orthologue scoA|Rv2504c (747 bp)  (Best blastx scores: 439);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	534770	535415	.	+	0	Locus=ML0435;Name=scoB;Function=;Product=Probable succinyl-CoA:3-ketoacid-CoA transferase [beta subunit] ScoB (pseudogene);Comments=ML0435, len: 646 bp. Possible pseudogene of M. tuberculosis orthologue scoB|Rv2503c (657 bp)  (Best blastx scores: 465);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	535415	537001	.	+	0	Locus=ML0436;Name=accD1;Function=;Product=Probable acetyl/propionyl-CoA carboxylase, [beta subunit] AccD1 (pseudogene);Comments=ML0436, len: 1587 bp. Possible pseudogene of M. tuberculosis orthologue accD1|Rv2502c (1590 bp) (Best blastx scores: 396);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	538599	539716	.	+	0	Locus=ML0438;Name=fadE19;Function=;Product=Possible acyl-CoA dehydrogenase FadE19 (MmgC) (pseudogene);Comments=ML0438, len: 1118 bp. Possible pseudogene of M. tuberculosis orthologue fadE19|Rv2500c (1185 bp) (Best blastx scores: 346);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	549367	550150	.	-	0	Locus=ML0449c;Name=tesB2;Function=;Product=Probable acyl-CoA thioesterase II TesB2 (TEII) (pseudogene);Comments=ML0449c, len: 784 bp. Possible pseudogene of M. tuberculosis orthologue tesB2|Rv2605c (846 bp) (Best blastx scores: 159);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	824242	825377	.	-	0	Locus=ML0688c;Name=nagA;Function=;Product=Probable N-acetylglucosamine-6-Phosphate deacetylase NagA (pseudogene);Comments=ML0688c, len: 1136 bp. Possible pseudogene of M. tuberculosis orthologue nagA|Rv3332 (1152 bp) (Best blastx scores: 253).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1708604	1709271	.	-	0	Locus=ML1421c;Name=ML1421c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1421c, len: 668 bp. Possible pseudogene of M. tuberculosis orthologue Rv2005c (888 bp) (Best blastx scores: 239).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	547993	548265	.	+	0	Locus=ML0448;Name=ML0448;Function=;Product=Hypothetical protein;Comments=ML0448, len: 90 aa. Hypothetical Unknown protein. Previously sequenced as O07143|Z96801 (90 aa), Fasta scores: E(): 0, (100.0% identity in 90 aa overlap).;UniProt_AC=O07143;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	557909	558314	.	-	0	Locus=ML0457c;Name=ML0457c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0457c, len: 406 bp. Possible pseudogene similar to M. tuberculosis Rv0356c (645 bp) (Best blastx scores: 97), also similar to ML0279c a possible orthologue of M. tuberculosis Rv0356c. ;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	559294	559667	.	+	0	Locus=ML0459;Name=ML0459;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0459, len: 374 bp. Possible pseudogene of M. tuberculosis orthologue Rv2616 (501 bp) (Best blastx scores: 154);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	559772	559990	.	-	0	Locus=ML0460c;Name=ML0460c;Function=;Product=Probable transmembrane protein (pseudogene);Comments=ML0460c, len: 219 bp. Possible pseudogene of M. tuberculosis orthologue Rv2617c (441 bp) (Best blastx scores: 163);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	560206	560552	.	+	0	Locus=ML0461;Name=ML0461;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0461, len: 347 bp. Possible pseudogene of M. tuberculosis orthologue Rv2618 (678 bp) (Best blastx scores: 222);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	561079	561564	.	-	0	Locus=ML0462c;Name=ML0462c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0462c, len: 486 bp. Possible pseudogene similar to M. tuberculosis Rv0021c (969 bp) (Best blastx scores: 169);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	561580	561829	.	-	0	Locus=ML0463c;Name=ML0463c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0463c, len: 250 bp. Possible pseudogene similar to M. tuberculosis Rv2619c (354 bp) (Best blastx scores: 147);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1508865	1509125	.	-	0	Locus=ML1265c;Name=ML1265c;Function=;Product=Possible conserved transmembrane protein (pseudogene);Comments=ML1265c, len: 261 bp. Possible pseudogene similar to M. tuberculosis Rv2345 (1983 bp) (Best blastx scores: 100) and also similar to Rv2689 and Rv1376. Also similar to ML0830c a possible pseudogene similar to M. tuberculosis Rv2345.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	574033	574275	.	+	0	Locus=ML0472;Name=ML0472;Function=;Product=Hypothetical protein;Comments=ML0472, len: 80 aa. Hypothetical unknown protein. Improbable CDS suggested by GC frameplot and codon usage plots. Possibly the remains of a disrupted gene.;UniProt_AC=Q9CCT7;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	555050	555670	.	-	0	Locus=ML0455c;Name=ML0455c;Function=;Product=Conserved hypothetical protein;Comments=ML0455c, len: 206 aa. Conserved hypothetical protein, highly similar to Rv2613c|O06201|AL123456 conserved hypothetical protein from M. tuberculosis (195 aa), Fasta scores: E(): 0, (84.7% identity in 196 aa overlap). Similar to many HIT-family hypothetical proteins e.g. Q9L279|SCL2.20 from Streptomyces coelicolor (186 aa), Fasta scores: E(): 0, (84.7% identity in 196 aa overlap); and Q9F7Z0 from Mycobacterium smegmatis (see citation below) (205 aa). Previously sequenced as O07150|Z96801 (186 aa), Fasta scores: E(): 0, (100.0% identity in 186 aa overlap). Contains Pfam match to entry PF01230 HIT, HIT family. In M. tuberculosis it seems the Rv2613c and downstream ORF Rv2612c|psgA1 are expressed from the same promoter (see citation below) and that Rv2613c should be involved in lipid metabolism.;UniProt_AC=Q9CCU0;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	562651	563431	.	+	0	Locus=ML0465;Name=ML0465;Function=;Product=Possible adenylate cyclase (pseudogene);Comments=ML0465, len: 781 bp. Possible pseudogene similar to M. tuberculosis (1626 bp), Rv1319c (1608 bp) or Rv1320c (1704 bp) (Best blastx scores: 85) also similar to ML1154c (pseudogene) a possible orthologue of M. tuberculosis of Rv1318c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	567987	569439	.	+	0	Locus=ML0469;Name=fadD13;Function=;Product=Probable fatty-acyl-CoA synthetase (pseudogene);Comments=ML0469, len: 1453 bp. Possible pseudogene similar to M. tuberculosis orthologue fadD13|Rv3089 (1512 bp) (Best blastx scores: 97).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	573280	573919	.	+	0	Locus=ML0471;Name=ML0471;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML0471, len: 640 bp. Possible pseudogene similar to M. tuberculosis Rv0051 (1683 bp) also similar to ML2687c a possible orthologue of M. tuberculosis Rv0051.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	577203	579168	.	-	0	Locus=ML0476c;Name=speE;Function=;Product=Probable spermidine synthase SpeE (pseudogene);Comments=ML0476c, len: 1966 bp. Possible pseudogene of M. tuberculosis orthologue speE|Rv2601 (1572 bp), interrupted by insertion of an RLEP repeat (Best blastx scores: 229).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	579688	580080	.	-	0	Locus=ML0478c;Name=ML0478c;Function=;Product=Probable conserved membrane protein (pseudogene);Comments=ML0478c, len: 393 bp. Possible pseudogene of M. tuberculosis orthologue Rv2599 (432 bp) (Best blastx scores: 115);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	561809	562096	.	+	0	Locus=ML0464;Name=ML0464;Function=;Product=hypothetical protein;Comments=ML0464, len: 95 aa. Hypothetical Unknown protein. Previously sequenced as O07155|Z96801 (110 aa), Fasta scores: E(): 0, (100.0% identity in 95 aa overlap).;UniProt_AC=Q9CCT8;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	571604	571894	.	-	0	Locus=ML0470c;Name=ML0470c;Function=;Product=Hypothetical protein;Comments=ML0470c, len: 96 aa. Hypothetical unknown protein. Previously sequenced as O07161|Z96801 (96 aa), Fasta scores: E(): 0, (100.0% identity in 96 aa overlap).;UniProt_AC=O07161;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	574539	574811	.	+	0	Locus=ML0473;Name=ML0473;Function=;Product=Hypothetical protein;Comments=ML0473, len: 90 aa. Hypothetical unknown protein. Improbable CDS suggested by GC frameplot and codon usage plots. Possibly the remains of a disrupted gene. Though similar in part to ML2478 hypothetical unknown protein from M. leprae (129 aa), Fasta scores: E(): 0, (38.2% identity in 55 aa overlap);UniProt_AC=Q9CCT6;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	594986	595505	.	+	0	Locus=ML0490;Name=apt;Function=;Product=Probable adenine phosphoribosyltransferase Apt (pseudogene);Comments=ML0490, len: 520 bp. Possible pseudogene of M. tuberculosis orthologue apt|Rv2584c (672 bp) (Best blastx scores: 222).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	642926	643497	.	-	0	Locus=ML0529c;Name=ML0529c;Function=;Product=Putative transferase (pseudogene);Comments=ML0529c, len: 572 bp. Possible pseudogene of M. tuberculosis orthologue Rv1377c (639 bp) (Best blastx scores: 217).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	643653	645021	.	-	0	Locus=ML0530c;Name=ML0530c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0530c, len: 1369 bp. Possible pseudogene of M. tuberculosis orthologue Rv1378c (1428 bp)  (Best blastx scores: 627).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	645042	645573	.	+	0	Locus=ML0531;Name=pyrR;Function=;Product=Probable pyrimidine operon regulatory protein PyrR (pseudogene);Comments=ML0531, len: 532 bp. Possible pseudogene of M. tuberculosis orthologue pyrR|Rv1379 (582 bp) (Best blastx scores: 355);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	621129	621843	.	-	0	Locus=ML0511c;Name=ML0511c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0511c, len: 715 bp. Possible pseudogene of M. tuberculosis orthologue Rv2558 (711 bp) (Best blastx scores: 199);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	601751	602326	.	+	0	Locus=ML0496;Name=ML0496;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0496, len: 576 bp. Possible pseudogene of M. tuberculosis orthologue Rv2578c (1023 bp) (Best blastx scores: 339);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	602343	603850	.	-	0	Locus=ML0497c;Name=ML0497c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0497c, len: 1508 bp. Possible pseudogene of M. tuberculosis orthologue Rv2577 (1590 bp) (Best blastx scores: 414).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	604111	604426	.	+	0	Locus=ML0498;Name=ML0498;Function=;Product=Possible conserved membrane protein (pseudogene);Comments=ML0498, len: 316 bp. Possible pseudogene of M. tuberculosis orthologue Rv2576c (465 bp) (Best blastx scores: 119).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	605197	606016	.	-	0	Locus=ML0499c;Name=ML0499c;Function=;Product=Possible conserved membrane glycine rich protein (pseudogene);Comments=ML0499c, len: 820 bp. Possible pseudogene of M. tuberculosis orthologue Rv2575 (882 bp) (Best blastx scores: 329).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	606109	606593	.	-	0	Locus=ML0500c;Name=ML0500c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0500c, len: 485 bp. Possible pseudogene of M. tuberculosis orthologue Rv2573 (741 bp) (Best blastx scores: 211).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	608648	609030	.	+	0	Locus=ML0502;Name=ML0502;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0502, len: 383 bp. Possible pseudogene similar to several M. tuberculosis conserved hypothetical proteins e.g Rv1558, Rv3547 and Rv3178 (Best blastx scores: 72);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	609985	610359	.	+	0	Locus=ML0503;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML0503, len: 375 bp. Possible pseudogene similar to several M. tuberculosis PPE genes e.g. PPE41|Rv2430c, PPE22|Rv1705c, PPE26|Rv1789, PPE15|Rv1039c and PPE43|Rv2768c (Best blastx scores: 98);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	601153	601598	.	+	0	Locus=ML0495;Name=PE_PGRS2;Function=;Product=PE_PGRS-family protein (pseudogene);Comments=ML0495, len: 446 bp. Possible pseudogene similar to M. tuberculosis PE_PGRS genes e.g PE_PGRS58, PE_PGRS26, PE_PGRS27 etc (Best blastx scores: 176).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	615181	617504	.	+	0	Locus=ML0507;Name=ML0507;Function=;Product=Conserved hypothetical alanine and leucine rich protein (pseudogene);Comments=ML0507, len: 2324 bp. Possible pseudogene similar to M. tuberculosis Rv2567 (2655 bp) (Best blastx scores: 542) and similar to M. leprae ML2679 a possible orthologue of M. tuberculosis Rv2567.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	618436	619451	.	+	0	Locus=ML0509;Name=ML0509;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0509, len: 1016 bp. Possible pseudogene of M. tuberculosis orthologue Rv2568c (1026 bp) (Best blastx scores: 271);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	599741	601024	.	+	0	Locus=ML0494;Name=hisS;Function=;Product=Probable histidyl-tRNA synthase HisS (Histidine--tRNA ligase) (HisRS) (Histidine--Translase);Comments=ML0494, len: 427 aa. Probable hisS, histidyl-tRNA synthetase (EC 6.1.1.21), highly similar to SYH_MYCTU|Q50641|Rv2580c hisS, histidyl-tRNA synthase from M. tuberculosis (423 aa), Fasta scores: E(): 9.9e-145, (85.9% identity in 417 aa overlap); and CAD94796|Mb2611c from M. bovis (423 aa). Also highly similar to many e.g. Q9KXP2|HISS from Streptomyces coelicolor (425 aa), FASTA scores: ; SYH_ECOLI|P04804 hisS, histidyl-tRNA synthase from Escherichia coli (423 aa), Fasta scores: (42.1% identity in 413 aa overlap). Previously sequenced as SYH_MYCLE|P46696 (427 aa), Fasta scores: E(): 0, (99.5% identity in 427 aa overlap). Contains Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II (G, H, P, S and T). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature. Belongs to the class-II aminoacyl-tRNA synthetase family.;UniProt_AC=P46696;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	647833	648322	.	+	0	Locus=ML0534;Name=ML0534;Function=;Product=Possible export or membrane protein (pseudogene);Comments=ML0534, len: 490 bp. Possible pseudogene of M. tuberculosis orthologue Rv1382 (498 bp) (Best blastx scores: 331).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	846401	847611	.	+	0	Locus=ML0708;Name=amiB1;Function=;Product=Probable aminohydrolase AmiB1 (pseudogene);Comments=ML0708, len: 1211 bp. Possible pseudogene of M. tuberculosis orthologue amiB1|Rv3306c (1185 bp) (Best blastx scores: 355).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	624887	625441	.	+	0	Locus=ML0513;Name=ML0513;Function=;Product=Conserved hypothetical protein;Comments=ML0513, len: 184 aa. Conserved hypothetical protein, highly similar to YP54_MYCTU|P94999|Rv2554c conserved hypothetical protein from M. tuberculosis (170 aa), Fasta scores: E(): 5.1e-40, (72.0% identity in 161 aa overlap); and CAD94769|Mb2584c from M. bovis (170 aa). Similar to many bacterial hypothetical proteins e.g. Q9KXQ0|SC9C5.24C hypothetical protein from Streptomyces coelicolor (167 aa), Fasta scores: E(): 8.9e-25, (54.8% identity in 155 aa overlap).;UniProt_AC=Q9CCS9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	638095	638980	.	-	0	Locus=ML0526c;Name=ML0526c;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML0526c, len: 886 bp. Possible pseudogene similar to M. tuberculosis Rv1260 (1119 bp)  (Best blastx scores: 110).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	641811	642796	.	-	0	Locus=ML0528c;Name=ML0528c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0528c, len: 986 bp. Possible pseudogene of M. tuberculosis orthologue Rv1367c (1134 bp) (Best blastx scores: 289);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	639679	639933	.	-	0	Locus=ML0527c;Name=ML0527c;Function=;Product=Hypothetical protein;Comments=ML0527c, len: 84 aa. Hypothetical protein.;UniProt_AC=Q9CCR6;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	631822	632952	.	+	0	Locus=ML0521;Name=pepQ;Function=;Product=Probable cytoplasmic peptidase PepQ;Comments=ML0521, len: 376 aa. Probable pepQ, cytoplasmic peptidase (EC 3.4.-.-), highly similar to P95018|AL123456|Rv2535c pepQ, putative cytoplasmic peptidase from M. tuberculosis (372 aa), Fasta scores: E(): 0, (83.0% identity in 376 aa overlap); and CAD94749|Mb2564c from M. bovis (372 aa). Similar to many e.g. P54518|YQHT_BACSU Putative peptidase yqhT from Bacillus subtilis (353 aa), FASTA scores: E(): 3.5e-42, (40.111% identity in 359 aa overlap). Contains Pfam match to entry PF00557 Peptidase_M24, metallopeptidase family M24. Contains PS00491 Aminopeptidase P and proline dipeptidase signature. Contains PS00211 ABC transporters family signature. Possibly belongs to the peptidase family M24B.;UniProt_AC=Q9CCS1;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	637493	637669	.	+	0	Locus=ML0525;Name=ML0525;Function=;Product=Conserved hypothetical protein;Comments=ML0525, len: 58 aa. Conserved hypothetical protein, weakly similar to O53218|AL123456|Rv2493 conserved hypothetical protein from M. tuberculosis (73 aa), Fasta scores: E(): 0.15, (47.7% identity in 44 aa overlap); and CAD94744|Mb2521 from M. bovis (73 aa).;UniProt_AC=Q9CCR7;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	684846	686399	.	+	0	Locus=ML0567;Name=ML0567;Function=;Product=Conserved membrane protein (pseudogene);Comments=ML0567, len: 1554 bp. Possible pseudogene of M. tuberculosis orthologue Rv1431 (1770 bp) (Best blastx scores: 550).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	691277	691439	.	+	0	Locus=ML0568B;Name=ML0568B;Function=;Product=Probable transposase (pseudogene);Comments=ML0568B, len: 163 bp. Possible pseudogene similar to several M. tuberculosis transposases associated with IS6110 (Best blastx scores: 75) and identical to ML1291c, ML1242A, ML0599A, ML1820A from M. leprae.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	666225	667067	.	-	0	Locus=ML0549c;Name=ML0549c;Function=;Product=Putative methyltransferase (pseudogene);Comments=ML0549c, len: 843 bp. Possible pseudogene of M. tuberculosis orthologue Rv1403c (825 bp) (Best blastx scores: 822).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	847646	848748	.	+	0	Locus=ML0709;Name=amiA1;Function=;Product=Possible N-acyl-L-amino acid amidohydrolase AmiA1 (pseudogene);Comments=ML0709, len: 1103 bp. Possible pseudogene of M. tuberculosis orthologue amiA1|Rv3305c (1170 bp) (Best blastx scores: 489).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1421621	1422381	.	+	0	Locus=ML1205;Name=ML1205;Function=;Product=Possible ketoacyl reductase (pseudogene);Comments=ML1205, len: 761 bp. Possible pseudogene of M. tuberculosis orthologue Rv1544 (804 bp) (Best blastx scores: 215). Also similar to ML2488 a possible pseudogene similar to M. tuberculosis Rv1544.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	670029	671363	.	+	0	Locus=ML0553;Name=fmu;Function=;Product=Probable Fmu protein (Sun protein)(pseudogene);Comments=ML0553, len: 1335 bp. Possible pseudogene of M. tuberculosis orthologue fmu|Rv1407 (1374 bp) (Best blastx scores: 1324).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	690749	690991	.	+	0	Locus=ML0568A;Name=ML0568A;Function=;Product=Conserved hypothetical protein;Comments=ML0568A, len: 80 aa. Conserved hypothetical protein, identical to the other hypothetical CDS  ML0599B and ML1292c from M. leprae.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	669004	669960	.	+	0	Locus=ML0552;Name=fmt;Function=MODIFIES THE FREE AMINO GROUP OF THE AMINOACYL MOIETY OF METHIONYL-TRNA(FMET). THE FORMYL GROUP APPEARS TO PLAY A DUAL ROLE IN THE INITIATOR IDENTITY OF N-FORMYLMETHIONYL-TRNA BY:(I) PROMOTING ITS RECOGNITION BY IF2 AND (II) IMPAIRING ITS BINDING TO EFTU-GTP. [CATALYTIC ACTIVITY : 10-FORMYLTETRAHYDROFOLATE + L-METHIONYL-TRNA + H(2)O = TETRAHYDROFOLATE + N-FORMYLMETHIONYL-TRNA] ;Product=Probable methionyl-tRNA formyltransferase Fmt;Comments=ML0552, len: 318 aa. Probable fmt, methionyl-tRNA formyltransferase (EC 2.1.2.9), highly similar to FMT_MYCTU|P71674|Rv1406 Probable fmt, methionyl-tRNA formyltransferase from M. tuberculosis (312 aa), Fasta scores: E(): 0, (81.0% identity in 316 aa overlap). Similar to many e.g. Q9L0Y6|FMT_STRCO Methionyl-tRNA formyltransferase from Streptomyces coelicolor (310 aa), fasta scores: E(): 4.7e-63, (57.962% identity in 314 aa overlap). Contains Pfam match to entry PF00551 formyl_transf, Formyl transferase. Belongs to the Fmt family.;UniProt_AC=Q9CCQ0;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	683867	684276	.	+	0	Locus=ML0566;Name=ML0566;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0566, len: 410 bp. Possible pseudogene of M. tuberculosis orthologue Rv1425 (1380 bp) (Best blastx scores: 264);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	740724	741532	.	-	0	Locus=ML0608c;Name=ML0608c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0608c, len: 809 bp. Possible pseudogene of M. tuberculosis orthologue Rv2407 (822 bp) (Best blastx scores: 558).;UniProt_AC=Q49744;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	741779	741992	.	+	0	Locus=ML0609;Name=ML0609;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0609, len: 214 bp. Possible pseudogene of M. tuberculosis orthologue Rv2406c (429 bp) (Best blastx scores: 134).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	742053	742615	.	-	0	Locus=ML0610c;Name=ML0610c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0610c, len: 563 bp. Possible pseudogene of M. tuberculosis orthologue Rv2405 (570 bp) (Best blastx scores: 219);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	697928	698203	.	+	0	Locus=ML0573;Name=ML0573;Function=;Product=Hypothetical protein;Comments=ML0573, len: 91 aa. Hypothetical protein. Previously sequenced as Q49684|U00013 (91 aa), Fasta scores: E(): 0, (98.9% identity in 91 aa overlap). Contains Pfam match to entry PF00121 TIM, Triosephosphate isomerase.;UniProt_AC=Q49684;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	698200	698517	.	+	0	Locus=ML0574;Name=ML0574;Function=;Product=Hypothetical protein;Comments=ML0574, len: 105 aa. Hypothetical protein. Previously sequenced as Q49680|U00013 (105 aa), Fasta scores: E(): 0, (99.0% identity in 105 aa overlap).;UniProt_AC=Q49680;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	698675	698893	.	+	0	Locus=ML0575;Name=ML0575;Function=;Product=Hypothetical protein;Comments=ML0575, len: 72 aa. Hypothetical protein.;UniProt_AC=Q9CCN6;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	699709	699939	.	+	0	Locus=ML0576;Name=ML0576;Function=;Product=Hypothetical protein;Comments=ML0576, len: 76 aa. Hypothetical protein. Previously sequenced as Q49681|U00013 (76 aa), Fasta scores: E(): 1.5e-31, (100.0% identity in 76 aa overlap).;UniProt_AC=Q49681;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	682780	683757	.	+	0	Locus=ML0565;Name=whiA;Function=;Product=Probable transcriptional regulatory protein WhiA;Comments=ML0565, len: 325 aa. Putative whiA, transcriptional regulatory protein, highly similar to P71692|AL123456|Rv1423 Putative whiA, transcriptional regulator from M. tuberculosis (325 aa), Fasta scores: E(): 9.5e-114, (92.0% identity in 325 aa overlap); and CAD94319|Mb1458 from M. bovis (325 aa). Similar to Q9S4Y1|AF106003 whiA, sporulation regulatory protein from Streptomyces coelicolor (330 aa), Fasta scores: E(): 5.5e-85, (67.6% identity in 324 aa overlap).;UniProt_AC=Q9CCN8;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	704919	706435	.	-	0	Locus=ML0581c;Name=zwf2;Function=;Product=Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (pseudogene);Comments=ML0581c, len: 1517 bp. Possible pseudogene of M. tuberculosis orthologue zwf2|Rv1447c (1545 bp) (Best blastx scores: 638).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	710905	711811	.	-	0	Locus=ML0585c;Name=qor;Function=;Product=Probable quinone reductase Qor (pseudogene);Comments=ML0585c, len: 907 bp. Possible pseudogene of M. tuberculosis orthologue qor|Rv1454c (987 bp) (Best blastx scores: 228);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	704002	704799	.	-	0	Locus=ML0580c;Name=opcA;Function=;Product=Putative OxPP cycle protein OpcA;Comments=ML0580c, len: 265 aa. Putative opcA, OxPP cycle protein, highly similar to O06813|AL123456|Rv1446c Putative opcA, OxPP cycle protein from M. tuberculosis (303 aa), Fasta scores: E(): 8.5e-66, (70.3% identity in 239 aa overlap); and CAD96148|Mb1481c from M. bovis (303 aa). Similar to Q8FT73 Putative oxppcycle protein OpcA from Corynebacterium efficiens (321 aa), fasta scores: E(): 9.9e-23, (34.826% identity in 201 aa overlap); and similar to several hypothetical proteins from Streptomyces coelicolor e.g. Q9XAB8|AL096839|SCC22.20 (351 aa), Fasta scores: E(): 7.1e-21, (36.0% identity in 203 aa overlap), although these have a short N-terminal extension relative to this homologue. Previously sequenced as Q49699|U00013 (265 aa), Fasta scores: E(): 0, (100.0% identity in 265 aa overlap).;UniProt_AC=Q49699;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	713859	714101	.	+	0	Locus=ML0588;Name=ML0588;Function=;Product=Hypothetical protein;Comments=ML0588, len: 80 aa. Hypothetical protein. Some similarity to several PPE family proteins e.g. P71657|Rv1387 PPE family protein from M. tuberculosis (539 aa), fasta scores: E(): 0.00072, (55.263% identity in 38 aa overlap). Previously sequenced as Q49686|U00013 (80 aa), Fasta scores: E(): 0, (98.8% identity in 80 aa overlap).;UniProt_AC=Q49686;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	707606	709705	.	-	0	Locus=ML0583c;Name=tkt;Function=This enzyme, together with transaldolase, provides a link between the glycolytic and pentose-phosphate pathways. It catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5-phosphate to an aldose receptor [Catalytic activity: Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate];Product=Probable transketolase Tkt (TK);Comments=ML0583c, len: 699 aa. Probable tkt, Transketolase (EC 2.2.1.1), highly similar to TKT_MYCTU|O06811|Rv1449c tkt, transketolase from M. tuberculosis (700 aa), Fasta scores: E(): 0, (89.1% identity in 700 aa overlap); and CAD96151|Mb1484c from M. bovis (700 aa). Similar to many e.g. TKT2_YEAST|P33315 tkl2, transketolase 2 from Saccharomyces cerevisiae (681 aa), Fasta scores: E(): 3.4e-99, (42.8% identity in 684 aa overlap). Previously sequenced as TKT_MYCLE|P46708 (699 aa), Fasta scores: E(): 0, (99.9% identity in 699 aa overlap). Contains Pfam match to entry PF00456 transketolase, Transketolase. Contains PS00801 Transketolase signature 1. Contains PS00802 Transketolase signature 2. Belongs to the Transketolase family. In M. tuberculosis tkt is thought to be differentially expressed within host cells (see Triccas et al., 1999).;UniProt_AC=P46708;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	725441	727010	.	-	0	Locus=ML0599c;Name=fadE15;Function=;Product=Probable acyl-CoA dehydrogenase FadE15 (pseudogene);Comments=ML0599c, len: 1570 bp. Possible pseudogene of M. tuberculosis orthologue fadE15|Rv1467c (1830 bp) (Best blastx scores: 267).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	727436	727598	.	-	0	Locus=ML0599A;Name=ML0599A;Function=;Product=Probable transposase (pseudogene);Comments=ML0599A, len: 163 bp. Possible pseudogene similar to several M. tuberculosis transposases associated with IS6110 (Best blastx scores: 75) and identical to ML1291c, ML1242A, ML1820A, ML0568B from M. leprae.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	731676	732619	.	-	0	Locus=ML0600c;Name=ML0600c;Function=;Product=Probable acyl-CoA dehydrogenase (pseudogene);Comments=ML0600c, len: 944 bp. Possible pseudogene similar to several acyl-CoA dehydrogenase in M. tuberculosis e.g. fadE26|Rv3504, fadE29|Rv3543c, fadE17|Rv1934c, fadE30|Rv3562 etc (Best blastx scores: 114);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	733141	733880	.	+	0	Locus=ML0601;Name=ML0601;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0601, len: 740 bp. Possible pseudogene of M. tuberculosis orthologue Rv2415c (894 bp) (Best blastx scores: 191);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	809937	810484	.	-	0	Locus=ML0673c;Name=ML0673c;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML0673c, len: 548 bp. Possible pseudogene of M. tuberculosis orthologue Rv3359 (1191 bp) (Best blastx scores: 307);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	733928	734849	.	+	0	Locus=ML0602;Name=ML0602;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0602, len: 922 bp. Possible pseudogene of M. tuberculosis orthologue Rv2414c (1545 bp) (Best blastx scores: 167).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	727883	728125	.	-	0	Locus=ML0599B;Name=ML0599B;Function=;Product=Conserved hypothetical protein;Comments=ML0599B, len: 80 aa. Conserved hypothetical protein, identical to the other hypothetical CDS ML0568A and ML1292c from M. leprae.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	729142	729540	.	-	0	Locus=ML0599D;Name=ML0599D;Function=;Product=Hypothetical protein;Comments=ML0599D, len: 132 aa. Hypothetical protein.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	729793	730215	.	-	0	Locus=ML0599E;Name=ML0599E;Function=;Product=Hypothetical protein;Comments=ML0599E, len: 140 aa. Hypothetical protein.;UniProt_AC=;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	724508	725005	.	+	0	Locus=ML0597;Name=ML0597;Function=;Product=Possible nitrogen fixation related protein;Comments=ML0597, len: 165 aa. Possible nitrogen fixation related protein, highly similar to O53156|AL123456|Rv1465 Possible nitrogen fixation related protein from M. tuberculosis (162 aa), Fasta scores: E(): 0, (79.4% identity in 165 aa overlap); and CAD96167|Mb1500 from M. bovis (162 aa). Also similar to O32163|NIFU_BACSU NifU-like protein from Bacillus subtilis (147 aa), fasta scores: E(): 9.5e-18, (41.481% identity in 135 aa overlap). Previously sequenced as Q49683|U00013 (165 aa), Fasta scores: E(): 0, (100.0% identity in 165 aa overlap). Contains Pfam match to entry PF01883 DUF59, Domain of unknown function. Contains Pfam match to entry PF01592 NifU_N, NifU-like N terminal domain.;UniProt_AC=Q49683;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	812528	813382	.	+	0	Locus=ML0677;Name=ML0677;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML0677, len: 855 bp. Possible pseudogene similar to M. tuberculosis Rv0063 and also similar to Rv3351 and Rv3353 (Best blastx scores: 243).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	744739	746655	.	-	0	Locus=ML0612c;Name=ML0612c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0612c, len: 1917 bp. Possible pseudogene of M. tuberculosis orthologue Rv2402 (1929 bp) (Best blastx scores: 1589).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	746876	747775	.	-	0	Locus=ML0613c;Name=ML0613c;Function=;Product=Probable oxidoreductase (pseudogene);Comments=ML0613c, len: 900 bp. Possible pseudogene similar to M. tuberculosis Rv1751 (1383 bp) (Best blastx scores: 134);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	749510	750256	.	+	0	Locus=ML0616;Name=cysT;Function=;Product=Probable sulphate transport integral membrane protein ABC transporter CysT (pseudogene);Comments=ML0616, len: 747 bp. Possible pseudogene of M. tuberculosis orthologue cysT|Rv2399c (852 bp) (Best blastx scores: 386).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	750259	750926	.	+	0	Locus=ML0617;Name=cysW;Function=;Product=Probable sulphate transport integral membrane protein ABC transporter CysW (pseudogene);Comments=ML0617, len: 668 bp. Possible pseudogene of M. tuberculosis orthologue cysW|Rv2398c (819 bp) (Best blastx scores: 281).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	751914	752429	.	-	0	Locus=ML0619c;Name=ML0619c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0619c, len: 516 bp. Possible pseudogene of M. tuberculosis orthologue Rv2387 (1254 bp) (Best blastx scores: 213);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	754091	754774	.	-	0	Locus=ML0621c;Name=ML0621c;Function=;Product=Possible alternative RNA polymerase sigma factor (pseudogene);Comments=ML0621c, len: 684 bp. Possible pseudogene similar to M. tuberculosis sigI gene (Best blastx scores: 110);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	754966	755391	.	-	0	Locus=ML0622c;Name=ML0622c;Function=;Product=Probable transposase fusion protein (pseudogene);Comments=ML0622c, len: 426 bp. Possible pseudogene similar to M. tuberculosis Rv3327 (1713 bp) (Best blastx scores: 106).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	755667	755985	.	-	0	Locus=ML0623c;Name=ML0623c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0623c, len: 319 bp. Possible pseudogene of M. tuberculosis orthologue Rv2375 (318 bp) (Best blastx scores: 230).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	761728	763013	.	+	0	Locus=ML0629;Name=ML0629;Function=;Product=Probable conserved transmembrane protein (pseudogene);Comments=ML0629, len: 1286 bp. Possible pseudogene of M. tuberculosis orthologue Rv2366c (1308 bp) (Best blastx scores: 651).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	736155	736415	.	-	0	Locus=ML0604c;Name=rpsT;Function=;Product=Probable 30S ribosomal protein S20 RpsT;Comments=ML0604c, len: 86 aa. Probable rpsT, 30s ribosomal protein s20, highly similar to RS20_MYCTU|P71731|Rv2412 rpsT, 30S ribosomal protein S20 from M. tuberculosis (86 aa), Fasta scores: E(): 8.8e-27, (87.2% identity in 86 aa overlap); and CAD97296|Mb2435 from M. bovis (86 aa). Similar to many e.g. RS20_ECOLI|P02378 rpsT, 30S ribosomal protein S20 from Escherichia coli (86 aa), Fasta scores: E(): 1.5e-08, (41.7% identity in 84 aa overlap). Previously sequenced as RS20_MYCLE|O33132 (86 aa), Fasta scores: E(): 2.1e-30, (98.8% identity in 86 aa overlap). Contains Pfam match to entry PF01649 Ribosomal_S20p, Ribosomal protein S20. Belongs to the S20P family of ribosomal proteins.;UniProt_AC=O33132;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	747778	748065	.	+	0	Locus=ML0614;Name=ML0614;Function=;Product=Possible conserved membrane protein;Comments=ML0614, len: 95 aa. Possible conserved membrane protein, similar but longer at the N terminus to Rv2401A possible conserved membrane protein from M. tuberculosis (67 aa), E(): 1.9e-15, (67.692% identity in 65 aa overlap); and CAD97285|Mb2424c possible conserved membrane protein from M. bovis (67 aa), fasta scores: E(): 4.9e-14, (66.154% identity in 65 aa overlap). Previously sequenced as Q49760|U00016 (95 aa), Fasta scores: E(): 0, (100.0% identity in 95 aa overlap).;UniProt_AC=Q49760;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	767996	768474	.	-	0	Locus=ML0636c;Name=ML0636c;Function=;Product=Possible lipoprotein (pseudogene);Comments=ML0636c, len: 479 bp. Possible pseudogene similar to M. tuberculosis lpqQ|Rv0835 (645 bp) (Best blastx scores: 118).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	768880	768987	.	-	0	Locus=ML0636A;Name=ML0636A;Function=;Product=Possible glutaredoxin protein (pseudo);Comments=ML0636A, len: 108 bp. Possible pseudogene similar to M. tuberculosis Rv3198A (255 bp) (Best blastx scores: 132).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	792431	793543	.	+	0	Locus=ML0655;Name=ML0655;Function=;Product=Possible conserved secreted protein (pseudogene);Comments=ML0655, len: 1113 bp. Possible pseudogene of M. tuberculosis orthologue Rv3163c (1272 bp) (Best blastx scores: 376);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	794102	794682	.	-	0	Locus=ML0657c;Name=nuoN;Function=;Product=Probable NADH dehydrogenase I (chain N) NuoN (pseudogene);Comments=ML0657c, len: 581 bp. Possible pseudogene of M. tuberculosis orthologue nuoN|Rv3158 (1596 bp) (Best blastx scores: 137).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	794995	795484	.	-	0	Locus=ML0658c;Name=fadB4;Function=;Product=Probable NADPH quinone oxidoreductase FadB4 (pseudogene);Comments=ML0658c, len: 490 bp. Possible pseudogene of M. tuberculosis orthologue fadB4|Rv3141  (972 bp) (Best blastx scores: 267);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	771427	771729	.	+	0	Locus=ML0638;Name=ML0638;Function=;Product=Possible secreted protein;Comments=ML0638, len: 100 aa. Possible secreted protein. Previously sequenced as Q49769|U00016 (100 aa), Fasta scores: E(): 0, (99.0% identity in 100 aa overlap). Contains a possible N-terminal signal sequence.;UniProt_AC=Q49769;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	759042	759815	.	+	0	Locus=ML0626;Name=ML0626;Function=;Product=Conserved hypothetical protein;Comments=ML0626, len: 257 aa. Conserved hypothetical protein, highly similar to O05826|AL123456|Rv2372c conserved hypothetical protein from M. tuberculosis (262 aa), Fasta scores: E(): 0, (76.9% identity in 255 aa overlap); and CAD97254|Mb2393c from M. bovis (262 aa). Similar to many bacterial hypothetical proteins e.g. Q9S3Y4|AF170561 sdrD, hypothetical protein from Streptomyces coelicolor (216 aa), Fasta scores: E(): 1.2e-28, (44.8% identity in 223 aa overlap). Previously sequenced as Q49763|U00016 (128 aa), Fasta scores: E(): 0, (100.0% identity in 126 aa overlap). Belongs to the UPF0088 family.;UniProt_AC=Q9CCN1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	773608	774444	.	-	0	Locus=ML0641c;Name=ML0641c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0641c, len: 837 bp. Possible pseudogene of M. tuberculosis orthologue Rv3196 (900 bp) (Best blastx scores: 289).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	782072	782520	.	+	0	Locus=ML0645;Name=ML0645;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0645, len: 449 bp. Possible pseudogene of M. tuberculosis orthologue Rv3172c (483 bp) (Best blastx scores: 176).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	783178	783858	.	+	0	Locus=ML0646;Name=hpx;Function=;Product=Possible non-heme haloperoxidase Hpx (pseudogene);Comments=ML0646, len: 681 bp. Possible pseudogene of M. tuberculosis orthologue hpx|Rv3171c (900 bp) (Best blastx scores: 187).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	786099	787166	.	-	0	Locus=ML0648c;Name=ML0648c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0648c, len: 1068 bp. Possible pseudogene of M. tuberculosis orthologue Rv3169 (1125 bp) (Best blastx scores: 168);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	787163	788297	.	-	0	Locus=ML0649c;Name=ML0649c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0649c, len: 1135 bp. Possible pseudogene of M. tuberculosis orthologue Rv3168 (1137 bp) (Best blastx scores: 320).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	788363	788663	.	+	0	Locus=ML0650;Name=ML0650;Function=;Product=Probable transcriptional regulator Probably TetR-family) (pseudogene);Comments=ML0650, len: 301 bp. Possible pseudogene of M. tuberculosis orthologue Rv3167c (627 bp) (Best blastx scores: 210);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	788695	789823	.	-	0	Locus=ML0651c;Name=ML0651c;Function=;Product=REP-family protein (pseudogene);Comments=ML0651c, len: 1129 bp. Possible pseudogene similar to M. tuberculosis REP-family proteins (Best blastx scores: 93);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	790109	791037	.	+	0	Locus=ML0652;Name=ML0652;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0652, len: 929 bp. Possible pseudogene of M. tuberculosis orthologue Rv3166c (960 bp) (Best blastx scores: 276).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	791049	791529	.	+	0	Locus=ML0653;Name=ML0653;Function=;Product=Hypothetical protein (pseudogene);Comments=ML0653, len: 481 bp. Possible pseudogene of M. tuberculosis orthologue Rv3165c (483 bp) (Best blastx scores: 151).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	791658	792393	.	+	0	Locus=ML0654;Name=moxR3;Function=;Product=Probable methanol dehydrogenase transcriptional regulatory protein MoxR3 (pseudogene);Comments=ML0654, len: 736 bp. Possible pseudogene of M. tuberculosis orthologue moxR3|Rv3164c (963 bp) (Best blastx scores: 249).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1776717	1777664	.	-	0	Locus=ML1475c;Name=ML1475c;Function=;Product=Probable oxidoreductase, beta subunit (pseudogene);Comments=ML1475c, len: 948 bp. Possible pseudogene of M. tuberculosis orthologue Rv2454c (1122 bp) (Best blastx scores: 505).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	800706	801967	.	+	0	Locus=ML0665;Name=agpS;Function=;Product=Possible alkyl-dihydroxyacetonephosphate synthase AgpS (pseudogene);Comments=ML0665, len: 1262 bp. Possible pseudogene of M. tuberculosis orthologue Rv3107c|agpS (1584 bp) (Best blastx scores: 234).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	804681	805480	.	+	0	Locus=ML0668;Name=ML0668;Function=;Product=Possible conserved transmembrane protein (pseudogene);Comments=ML0668, len: 800 bp. Possible pseudogene of M. tuberculosis orthologue Rv3104c (927 bp) (Best blastx scores: 303).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	800117	800380	.	+	0	Locus=ML0664;Name=ML0664;Function=;Product=Hypothetical protein;Comments=ML0664, len: 87 aa. Hypothetical protein.;UniProt_AC=Q9CCM5;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	799662	799976	.	+	0	Locus=ML0663;Name=ML0663;Function=;Product=Conserved hypothetical protein;Comments=ML0663, len: 104 aa. Conserved hypothetical protein, highly similar to Q8VJ68|MT3222 Hypothetical protein from M. tuberculosis strain CDC1551 (110 aa), fasta scores:  opt: 483, E(): 1e-27, (69.307% identity in 101 aa overlap). Previously sequenced as O32888|Z98271 (104 aa), Fasta scores: E(): 0, (99.0% identity in 104 aa overlap).;UniProt_AC=O32888;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	808149	808842	.	+	0	Locus=ML0672;Name=ML0672;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0672, len: 694 bp. Possible pseudogene of M. tuberculosis orthologue Rv3099c (852 bp) (Best blastx scores: 271).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	814993	816276	.	+	0	Locus=ML0680;Name=ML0680;Function=;Product=REP-family protein (pseudogene);Comments=ML0680, len: 1284 bp. Possible pseudogene similar to M. tuberculosis REP-family proteins (Best blastx scores: 392);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	816354	817056	.	-	0	Locus=ML0681c;Name=ML0681c;Function=;Product=Possible methyltransferase (pseudogene);Comments=ML0681c, len: 703 bp. Possible pseudogene of M. tuberculosis orthologue Rv3342 (732 bp) (Best blastx scores: 374).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	818273	819513	.	-	0	Locus=ML0683c;Name=metC;Function=;Product=Probable O-acetyl-L-homoserine sulfhydrylase MetC (pseudogene);Comments=ML0683c, len: 1241 bp. Possible pseudogene of M. tuberculosis orthologue metC|Rv3340 (1350 bp) (Best blastx scores: 582);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	819972	821101	.	+	0	Locus=ML0684;Name=icd1;Function=;Product=Probable isocitrate dehydrogenase Icd1 (pseudogene);Comments=ML0684, len: 1130 bp. Possible pseudogene of M. tuberculosis orthologue icd1|Rv3339c (1230 bp) (Best blastx scores: 480);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	813433	813960	.	-	0	Locus=ML0678c;Name=ML0678c;Function=;Product=Hypothetical protein;Comments=ML0678c, len: 175 aa. Hypothetical protein. Previously sequenced as O32876|Z98271 (175 aa), Fasta scores: E(): 0, (99.4% identity in 175 aa overlap).;UniProt_AC=O32876;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	811544	811819	.	+	0	Locus=ML0675;Name=ML0675;Function=;Product=Probable integral membrane protein;Comments=ML0675, len: 91 aa. Probable integral membrane protein highly similar to O50384|AL123456|Rv3355c Probable integral membrane protein from M. tuberculosis (97 aa), Fasta scores: E(): 1.2e-24, (77.9% identity in 95 aa overlap); and CAD95535|Mb3390c from M. bovis (97 aa). Also similar to O50377|Rv3346c Hypothetical protein from M. tuberculosis (85 aa), fasta scores: E(): 5.2e-18, (68.421% identity in 95 aa overlap). Previously sequenced as O32878|Z98271 (91 aa), Fasta scores: E(): 0, (98.9% identity in 91 aa overlap).;UniProt_AC=O32878;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	811816	812292	.	-	0	Locus=ML0676c;Name=ML0676c;Function=;Product=Conserved hypothetical protein;Comments=ML0676c, len: 158 aa. Conserved hypothetical protein, highly similar to O50383|AL123456|Rv3354 conserved hypothetical protein from M. tuberculosis (129 aa), Fasta scores: E(): 6.2e-24, (55.9% identity in 127 aa overlap) and CAD95533|Mb3389 from M. bovis (129 aa). Also similar to O33192|AL123456|Rv1690, probable lipoprotein lprJ from M. tuberculosis (127 aa), Fasta scores: E(): 2e-09, (33.3% identity in 105 aa overlap). Previously sequenced as O32877|Z98271 (168 aa), Fasta scores: E(): 0, (100.0% identity in 158 aa overlap).;UniProt_AC=Q9CCM4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	825392	826049	.	-	0	Locus=ML0689c;Name=ML0689c;Function=;Product=Probable glucosamine-fructose-6-phosphate aminotransferase (pseudogene);Comments=ML0689c, len: 658 bp. Possible pseudogene similar to M. tuberculosis glmS (1875 bp), (Best blastx scores: 90), also similar to ML0371 a possible orthologue of M. tuberculosis glmS.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	826328	827764	.	-	0	Locus=ML0690c;Name=sugI;Function=;Product=Probable sugar transport integral membrane protein SugI (pseudogene);Comments=ML0690c, len: 1437 bp. Possible pseudogene of M. tuberculosis orthologue sugI|Rv3331  (1509 bp) (Best blastx scores: 360). Also similar to ML2511 a possible pseudogene similar to M. tuberculosis sugI.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	830043	831173	.	-	0	Locus=ML0692c;Name=ML0692c;Function=;Product=Probable aminotransferase (pseudogene);Comments=ML0692c, len: 1131 bp. Possible pseudogene of M. tuberculosis orthologue Rv3329 (1317 bp) (Best blastx scores: 840).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	831184	831979	.	+	0	Locus=ML0693;Name=sigJ;Function=;Product=Probable alternative RNA polymerase sigma factor, ECF family SigJ (pseudogene);Comments=ML0693, len: 796 bp. Possible pseudogene of M. tuberculosis orthologue sigJ|Rv3328c (939 bp) (Best blastx scores: 342).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	832027	832537	.	-	0	Locus=ML0694c;Name=ML0694c;Function=;Product=Probable transposase fusion protein (pseudogene);Comments=ML0694c, len: 511 bp. Possible pseudogene of M. tuberculosis orthologue Rv3327 (1713 bp) (Best blastx scores: 175).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	833166	833502	.	+	0	Locus=ML0695;Name=ML0695;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML0695, len: 337 bp. Possible pseudogene similar to M. tuberculosis Rv2893 (978 bp) (Best blastx scores: 106).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	897494	897754	.	-	0	Locus=ML0755c;Name=ML0755c;Function=;Product=conserved hypothetical protein;Comments=ML0755c, len: 86 aa. Conserved hypothetical protein, some similarity to Q9FCJ0 Hypothetical protein SCO5198 from Streptomyces coelicolor (171 aa), fasta scores:  E(): 0.0049, (40.299% identity in 67 aa overlap);UniProt_AC=Q9CCK5;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	823170	824111	.	+	0	Locus=ML0687;Name=ML0687;Function=;Product=Probable conserved integral membrane protein;Comments=ML0687, len: 313 aa. Probable conserved integral membrane protein, highly similar to O53385|AL123456|Rv3335c conserved integral membrane protein from M. tuberculosis (289 aa), Fasta scores: E(): 0, (68.8% identity in 288 aa overlap); and from CAD95487| M. bovis (289 aa). Similar to several bacterial hypothetical proteins e.g. YHJD_ECOLI|P37642 yhjD, hypothetical protein from Escherichia coli (337 aa), Fasta scores: E(): 5e-30, (34.9% identity in 278 aa overlap); and Q8ZA35 Putative membrane protein from Yersinia pestis (360 aa), fasta scores: E(): 1.9e-31, (35.689% identity in 283 aa overlap). Previously sequenced as Q49909|U00022 (313 aa), Fasta scores: E(): 0, (100.0% identity in 313 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q49909;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	838835	839853	.	+	0	Locus=ML0701;Name=ML0701;Function=;Product=Probable membrane protein (pseudogene);Comments=ML0701, len: 1019 bp. Possible pseudogene similar to M. tuberculosis Rv1481 (1008 bp) (Best blastx scores: 222), and similar to ML0702.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	839857	840814	.	-	0	Locus=ML0702c;Name=ML0702c;Function=;Product=Probable membrane protein (pseudogene);Comments=ML0702c, len: 958 bp. Possible pseudogene similar to  M. tuberculosis Rv1481 (1008 bp) (Best blastx scores: 92), and similar to ML0701.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	842233	843070	.	-	0	Locus=ML0704c;Name=ML0704c;Function=;Product=Possible acid phosphatase (pseudogene);Comments=ML0704c, len: 838 bp. Possible pseudogene of M. tuberculosis orthologue Rv3310 (900 bp) (Best blastx scores: 491).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	843206	843832	.	+	0	Locus=ML0705;Name=upp;Function=;Product=Probable uracil phophoribosyltransferase Upp (pseudogene);Comments=ML0705, len: 627 bp. Possible pseudogene of M. tuberculosis orthologue upp|Rv3309c (624 bp) (Best blastx scores: 251).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	848944	849543	.	+	0	Locus=ML0710;Name=ML0710;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0710, len: 600 bp. Possible pseudogene similar to M. tuberculosis Rv2248 (816 bp) (Best blastx scores: 255).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	850437	851855	.	+	0	Locus=ML0712;Name=lpdA;Function=;Product=Probable dihydrolipoamide dehydrogenase LpdA (pseudogene);Comments=ML0712, len: 1419 bp. Possible pseudogene of M. tuberculosis orthologue lpdA|Rv3303c (1482 bp) (Best blastx scores: 410).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	853694	854514	.	+	0	Locus=ML0714;Name=ML0714;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0714, len: 821 bp. Possible pseudogene of M. tuberculosis orthologue Rv3300c (918 bp) (Best blastx scores: 559).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	856125	859814	.	-	0	Locus=ML0716c;Name=lhr;Function=;Product=Probable ATP-dependent helicase Lhr (pseudogene);Comments=ML0716c, len: 3690 bp. Possible pseudogene of M. tuberculosis orthologue lhr|Rv3296  (4542 bp) (Best blastx scores: 824);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	862130	863300	.	-	0	Locus=ML0719c;Name=ML0719c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0719c, len: 1171 bp. Possible pseudogene of M. tuberculosis orthologue Rv3292 (1248 bp) (Best blastx scores: 499).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	863878	865226	.	+	0	Locus=ML0721;Name=lat;Function=;Product=Probable lysine-epsilon aminotransferase Lat (pseudogene);Comments=ML0721, len: 1349 bp. Possible pseudogene of M. tuberculosis orthologue lat|Rv3290c (1350 bp) (Best blastx scores: 509).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	865372	865701	.	+	0	Locus=ML0722;Name=ML0722;Function=;Product=Possible transmembrane protein (pseudogene);Comments=ML0722, len: 330 bp. Possible pseudogene of M. tuberculosis orthologue Rv3289c (378 bp) (Best blastx scores: 261).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	865726	866097	.	+	0	Locus=ML0723;Name=usfY;Function=;Product=Putative protein UsfY (pseudogene);Comments=ML0723, len: 372 bp. Possible pseudogene of M. tuberculosis orthologue Rv3288c|usfY (414 bp) (Best blastx scores: 210);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	866037	866822	.	+	0	Locus=ML0724;Name=rsbW;Function=;Product=Anti-sigma factor RsbW (pseudogene);Comments=ML0724, len: 786 bp. Possible pseudogene of M. tuberculosis orthologue rsbW|Rv3287c (438 bp) (Best blastx scores: 286).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	866918	867686	.	+	0	Locus=ML0725;Name=sigF;Function=;Product=Alternate RNA polymerase sigma factor (ECF subfamily) SigF (pseudogene);Comments=ML0725, len: 769 bp. Possible pseudogene of M. tuberculosis orthologue sigF|Rv3286c (786 bp) (Best blastx scores: 406).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	869613	870012	.	-	0	Locus=ML0727c;Name=ML0727c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0727c, len: 400 bp. Possible pseudogene of M. tuberculosis orthologue Rv3284 (432 bp) (Best blastx scores: 203).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	860657	861953	.	-	0	Locus=ML0718c;Name=pcd;Function=;Product=Probable piperideine-6-carboxylic acid dehydrogenase Pcd (pseudogene);Comments=ML0718c, len: 1297 bp. Possible pseudogene of M. tuberculosis orthologue pcd|Rv3293 (1485 bp) (Best blastx scores: 421).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1011356	1011966	.	-	0	Locus=ML0851c;Name=sirR;Function=;Product=Probable transcriptional repressor SirR (pseudogene);Comments=ML0851c, len: 611 bp. Possible pseudogene of M. tuberculosis orthologue sirR|Rv2788 (687 bp) (Best blastx scores: 192).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	899661	900353	.	-	0	Locus=ML0757c;Name=ML0757c;Function=;Product=hypothetical protein;Comments=ML0757c, len: 230 aa. Hypothetical protein, shows some similarity to Q8VJ42 Hypothetical protein MT3362 from M. tuberculosis CDC1551 (44 aa), fasta scores: E(): 0.00082, (77.419% identity in 31 aa overlap).;UniProt_AC=Q9CCK3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	849829	850308	.	-	0	Locus=ML0711c;Name=ML0711c;Function=;Product=Conserved hypothetical protein;Comments=ML0711c, len: 159 aa. Conserved hypothetical protein, highly similar to O53356|AL123456|Rv3304 conserved hypothetical protein from M. tuberculosis (159 aa), Fasta scores: E(): 9.2e-64, (91.8% identity in 159 aa overlap); and CAD95424|Mb from M. bovis (159 aa). Similiar to Q82I17 Hypothetical protein from Streptomyces avermitilis (145 aa), fasta scores: opt: 612, E(): 2.3e-34, (59.184% identity in 147 aa overlap). Shows weak similarity to other hypothetical proteins e.g. Q44546|M23528 hypothetical protein from Azotobacter vinelandii (183 aa), Fasta scores: E(): 1.3e-06, (30.1% identity in 146 aa overlap).  Previously sequenced as Q49927|U00022 (174 aa), Fasta scores: E(): 0, (98.7% identity in 149 aa overlap).;UniProt_AC=Q9CCL6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	879535	880519	.	-	0	Locus=ML0739c;Name=pstC1;Function=;Product=Phosphate-transport integral membrane ABC transporter PstC1 (pseudogene);Comments=ML0739c, len: 985 bp. Possible pseudogene of M. tuberculosis orthologue pstC|Rv0935 (1017 bp) (Best blastx scores: 346).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	881784	882589	.	-	0	Locus=ML0741c;Name=pstB;Function=;Product=Phosphate-transport ATP-binding protein ABC transporter PstB (pseudogene);Comments=ML0741c, len: 806 bp. Possible pseudogene of M. tuberculosis orthologue pstB|Rv0933 (831 bp) (Best blastx scores: 307);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	871120	871761	.	-	0	Locus=ML0729c;Name=ML0729c;Function=;Product=Conserved hypothetical protein;Comments=ML0729c, len: 213 aa. Conserved hypothetical protein, similar to P96887|AL123456|Rv3282 conserved hypothetical protein from M. tuberculosis (222 aa), Fasta scores: E(): 2.7e-57, (68.5% identity in 213 aa overlap); and CAD95402| from M. bovis (222 aa). Similar to maf-family proteins and other hypothetical proteins e.g. MAF_BACSU|Q02169 maf, protein involved in septum formation from Bacillus subtilis (189 aa), Fasta scores: E(): 4.8e-08, (29.1% identity in 196 aa overlap). Also similar to the N-terminal half of O95671|Y15521 asmtl, acetylserotonin methytransferase-like gene from Homo sapiens (629 aa), Fasta scores: E(): 2.1e-09, (31.6% identity in 193 aa overlap). Previously sequenced as Q49670|U00012 (213 aa), Fasta scores: E(): 0, (100.0% identity in 213 aa overlap).;UniProt_AC=Q49670;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	884242	885772	.	+	0	Locus=ML0743;Name=pknD;Function=;Product=Transmembrane serine-threonine protein kinase D PknD (pseudogene);Comments=ML0743, len: 1531 bp. Possible pseudogene of M. tuberculosis orthologue pknD|Rv0931c (1995 bp) (Best blastx scores: 458).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	885849	886982	.	-	0	Locus=ML0744c;Name=ML0744c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0744c, len: 1134 bp. Possible pseudogene of M. tuberculosis orthologue Rv3272 (1185 bp) (Best blastx scores: 782).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	887114	887967	.	-	0	Locus=ML0745c;Name=ML0745c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0745c, len: 854 bp. Possible pseudogene similar to several M. tuberculosis conserved hypothetical proteins e.g. Rv0731c, Rv3399, Rv3787 and Rv1729c (Best blastx scores: ).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	888119	888694	.	+	0	Locus=ML0746;Name=ML0746;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML0746, len: 576 bp. Possible pseudogene of M. tuberculosis orthologue Rv3271c (669 bp) (Best blastx scores: 151).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	891409	892025	.	-	0	Locus=ML0749c;Name=ML0749c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0749c, len: 617 bp. Possible pseudogene of M. tuberculosis orthologue Rv3268 (690 bp) (Best blastx scores: 385);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	896666	897427	.	+	0	Locus=ML0754;Name=ML0754;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0754, len: 762 bp. Possible pseudogene similar to several M. tuberculosis conserved hypothetical protein e.g. Rv3714, Rv3517, Rv1482, Rv1073 and Rv3555 (Best blastx scores: 231).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1094008	1094115	.	-	0	Locus=ML0924A;Name=ML0924A;Function=;Product=Probable conserved membrane protein,;Comments=ML0924A, len: 108 bp. Possible pseudogene similar to the N-terminus of Rv2219A from M. tuberculosis (Best blastx score: 71).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	911578	912771	.	+	0	Locus=ML0768;Name=alkB;Function=;Product=Probable transmembrane alkane 1-monooxygenase alkB (pseudogene);Comments=ML0768, len: 1194 bp. Possible pseudogene of M. tuberculosis orthologue Rv3252c|alkB (1251 bp) (Best blastx scores: 358).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	912780	912896	.	+	0	Locus=ML0769;Name=rubB;Function=;Product=Probable rubredoxin RubB (pseudogene);Comments=ML0769, len: 117 bp. Possible pseudogene of M. tuberculosis orthologue Rv3250c|rubB (183 bp) or Rv3251c|rubA (168 bp) (Best blastx scores: 105).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	912999	913509	.	+	0	Locus=ML0770;Name=ML0770;Function=;Product=Possible transcriptional regulatory protein (Probably TetR-family) (pseudogene);Comments=ML0770, len: 511 bp. Possible pseudogene of M. tuberculosis orthologue Rv3249c (636 bp) (Best blastx scores: 273);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1017531	1018540	.	+	0	Locus=ML0856;Name=ML0856;Function=;Product=Possible alanine rich oxidoreductase (pseudogene);Comments=ML0856, len: 1010 bp. Possible pseudogene of M. tuberculosis orthologue Rv2781c (1035 bp) (Best blastx scores: 337).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1422521	1422943	.	+	0	Locus=ML1206;Name=ML1206;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1206, len: 423 bp. Possible pseudogene of M. tuberculosis orthologue Rv1546 (432 bp) (Best blastx scores: 213).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	906079	907176	.	+	0	Locus=ML0764;Name=ML0764;Function=;Product=conserved hypothetical protein;Comments=ML0764, len: 365 aa. Conserved hypothetical protein, highly similar to Rv3256c|O05899|Z95121 Conserved hypothetical protein from M. tuberculosis (346 aa), fasta scores: E(): 0, (75.3% identity in 365 aa overlap); and CAD95376|Mb3284c from M. bovis (346 aa). Also similar to other hypothetical bacterial proteins e.g. Q8FRJ8 Conserved hypothetical protein from Corynebacterium efficiens (329 aa), fasta scores: E(): 7.4e-11, (30.258% identity in 271 aa overlap).;UniProt_AC=Q9CCJ6;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	903228	903497	.	+	0	Locus=ML0760;Name=whiB2;Function=;Product=Probable transcriptional regulatory protein WhiB-like WhiB2;Comments=ML0760, len: 89 aa. Probable whiB2 (alternate gene name: whmD), WhiB-like regulatory protein (see Hutter & Dick 1999), similar to Q53963|X62287 WhiB paralogue of Streptomyces coelicolor (85 aa), fasta scores: E(): 4.8e-26, (85.5% identity in 69 aa overlap). Highly similar to  Rv3260c|MTV015.05c|O53353|AL021840 whiB2 regulatory protein from Mycobacterium tuberculosis (89 aa), fasta scores: E(): 0, (85.4% identity in 89 aa overlap); to Q9S426|AF164439 whmD regulatory protein (see Gomez & Bishai 2000) from Mycobacterium smegmatis (129 aa), fasta scores: E(): 1.6e-29, (84.1% identity in 82 aa overlap). Also similar to ML0382, ML0639, ML0804 and ML2307 from M. leprae.;UniProt_AC=Q9CCK0;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	924815	925330	.	+	0	Locus=ML0780;Name=ML0780;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML0780, len: 516 bp. Possible pseudogene of M. tuberculosis orthologue Rv3238c (735 bp) (Best blastx scores: 169).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	927402	927983	.	-	0	Locus=ML0783c;Name=ML0783c;Function=;Product=Hypothetical alanine, arginine and proline rich protein (pseudogene);Comments=ML0783c, len: 582 bp. Possible pseudogene of M. tuberculosis orthologue Rv3235 (642 bp) (Best blastx scores: 155).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	928182	928875	.	+	0	Locus=ML0784;Name=ML0784;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0784, len: 694 bp. Possible pseudogene of M. tuberculosis orthologue Rv3234c (816 bp) (Best blastx scores: 286).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	928968	929497	.	+	0	Locus=ML0785;Name=ML0785;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0785, len: 530 bp. Possible pseudogene of M. tuberculosis orthologue Rv3233c (591 bp) (Best blastx scores: 202).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	929728	930224	.	+	0	Locus=ML0786;Name=pvdS;Function=;Product=Possible alternative RNA polymerase sigma factor PvdS (pseudogene);Comments=ML0786, len: 497 bp. Possible pseudogene of M. tuberculosis orthologue Rv3232c|pvdS (888 bp) (Best blastx scores: 85).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	930317	930631	.	+	0	Locus=ML0787;Name=ML0787;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0787, len: 315 bp. Possible pseudogene of M. tuberculosis orthologue Rv3231c (510 bp) (Best blastx scores: 184);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	930895	931943	.	+	0	Locus=ML0788;Name=ML0788;Function=;Product=Putative oxidoreductase (pseudogene);Comments=ML0788, len: 1049 bp. Possible pseudogene of M. tuberculosis orthologue Rv3230c (1143 bp) (Best blastx scores: 278).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	933511	934327	.	-	0	Locus=ML0790c;Name=ML0790c;Function=;Product=Probable beta-ketoacyl-CoA thiolase (pseudogene);Comments=ML0790c, len: 817 bp. Possible pseudogene similar to M. tuberculosis fadA3|Rv1074c (1218 bp) (Best blastx scores: 143) and to fadA6 and fadA5.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1031320	1032062	.	-	0	Locus=ML0867c;Name=cobS;Function=;Product=Probable cobalamin (5'-phosphate) synthase CobS (pseudogene);Comments=ML0867c, len: 743 bp. Possible pseudogene of M. tuberculosis orthologue cobS|Rv2208 (750 bp) (Best blastx scores: 348).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1918059	1918506	.	-	0	Locus=ML1593c;Name=ML1593c;Function=;Product=Immunogenic protein (pseudogene);Comments=ML1593c, len: 448 bp. Possible pseudogene similar to M. tuberculosis Rv1926c|mpt63 (480 bp) (Best blastx scores: 67).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	920656	920850	.	+	0	Locus=ML0777;Name=ML0777;Function=;Product=hypothetical protein;Comments=ML0777, len: 64 aa. Hypothetical protein.;UniProt_AC=Q9CCI8;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	920259	920516	.	+	0	Locus=ML0776;Name=ML0776;Function=;Product=conserved hypothetical protein;Comments=ML0776, len: 85 aa. Conserved hypothetical protein, highly similar to the N-terminal half of Rv3242c|MTCY20B11.17c|O05887 Conserved hypothetical protein from Mycobacterium tuberculosis (213 aa),  fasta scores: E(): 6.8e-18, (78.1% identity in 64 aa); and CAD95362| from M. bovis (213 aa).;UniProt_AC=Q9CCI9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	920954	921643	.	+	0	Locus=ML0778;Name=ML0778;Function=;Product=conserved hypothetical protein;Comments=ML0778, len: 229 aa. Conserved hypothetical protein, similar to many hypothetical proteins and to some putative ribosomal proteins e.g. Rv3241c|MTCY20B11.16c|O05886|Z95121 Conserved hypothetical protein from Mycobacterium tuberculosis (213 aa), fasta scores: E(): 4.4e-79, (89.3% identity in 206 aa); and RR30_SPIOL|P19954 30s ribosomal protein S30, chloroplast precursor RPS30 from Spinacia oleracea (302 aa), fasta scores: E(): 1.3e-10, (26.8% identity in 213 aa).;UniProt_AC=Q9CCI7;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	937637	938914	.	-	0	Locus=ML0794c;Name=ML0794c;Function=;Product=REP-family protein (pseudogene);Comments=ML0794c, len: 1278 bp. Possible pseudogene similar to M. tuberculosis REP-family proteins (Best blastx scores: 135);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	939223	941361	.	-	0	Locus=ML0795c;Name=atsD;Function=;Product=Possible arylsulfatase AtsD (pseudogene);Comments=ML0795c, len: 2139 bp. Possible pseudogene of M. tuberculosis orthologue atsD|Rv0663 (2367 bp) (Best blastx scores: 485).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1509242	1510184	.	-	0	Locus=ML1266c;Name=ML1266c;Function=;Product=Membrane serine-threonine protein kinase (pseudogene);Comments=ML1266c, len: 943 bp. Possible pseudogene similar to M. tuberculosis pknF|Rv1746 (1431 bp) (Best blastx scores: 141) and similar to pknJ|Rv2088 and pknI|Rv2914c. Also similar to ML1386 a possible pseudogene similar to M. tuberculosis pknF.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1427779	1428215	.	+	0	Locus=ML1208;Name=ML1208;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1208, len: 437 bp. Possible pseudogene of M. tuberculosis orthologue Rv1558 (447 bp) (Best blastx scores: 405).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	934529	935512	.	-	0	Locus=ML0791c;Name=ML0791c;Function=;Product=conserved hypothetical protein;Comments=ML0791c, len: 327 aa. Conserved hypothetical protein, highly similar to Rv3228|MTCY20B11.03|O05873|Z95121 Conserved hypothetical protein from M.tuberculosis (330 aa), fasta scores: E(): 0, (84.0% identity in 331 aa); and CAD95349| from M. bovis (330 aa). Also similar to several hypothetical bacterial proteins e.g. Q9K4A8|SC7E4.08c from Streptomyces coelicolor (337 aa), FASTA scores: E(): 3.7e-43 (54.819% identity in 332 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop).;UniProt_AC=Q9CCI4;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	881072	881655	.	-	0	Locus=ML0740c;Name=pstS1;Function=;Product=Periplasmic phosphate-binding lipoprotein PstS1 (pseudogene);Comments=ML0740c, len: 584 bp. Possible pseudogene of M. tuberculosis orthologue pstS1|Rv0934 (1125 bp) (Best blastx scores: 238).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1430415	1431246	.	+	0	Locus=ML1210;Name=ML1210;Function=;Product=Putative transcriptional regulatory protein (pseudogene);Comments=ML1210, len: 832 bp. Possible pseudogene similar to several transcriptional regulators e.g. Q827C4 Putative GntR-family transcriptional regulator from Streptomyces avermitilis (Best blastx scores: 195).;UniProt_AC=Q9CC69;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	753533	754036	.	+	0	Locus=ML0620;Name=cfp2;Function=;Product=Low molecular weight antigen, secreted protein;Comments=ML0620, len: 167 aa. cfp2 (alternate gene name: mtb12), low molecular weight antigen, secreted protein, similar to MB12_MYCTU|O05822|Rv2376c cfp2, low molecular weight antigen from M. tuberculosis (168 aa), Fasta scores: E(): 0, (65.5% identity in 165 aa overlap); and CAD97258|Mb2397c from M. bovis (168 aa). Previously sequenced as MB12_MYCLE|Q49771 (165 aa), Fasta scores: E(): 0, (100.0% identity in 165 aa overlap). Belongs to the mtb12 family.;UniProt_AC=Q49771;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	760115	761164	.	+	0	Locus=ML0627;Name=phoH1;Function=;Product=Probable phoH-like protein PhoH1 (Phosphate starvation-inducible protein PsiH);Comments=ML0627, len: 329 aa. Probable phoH1, phoH-like protein (phosphate starvation-induced protein), probably ATP-binding protein, highly similar to PHOL_MYCTU|O05830|Rv2368c phoH, phoH-family protein from M. tuberculosis (352 aa), Fasta scores: E(): 1.4e-116, (88.9% identity in 352 aa overlap); and CAD97250|Mb2389c from M. bovis (352 aa). Similar to others e.g. PHOH_ECOLI|P31544 phoH, phosphate starvation-inducible protein from Escherichia coli (354 aa), Fasta scores: E(): 1.2e-29, (36.8% identity in 304 aa overlap). Some similarity to ML1951 from M. leprae. Previously sequenced as PHOL_MYCLE|Q49751 (349 aa), Fasta scores: E(): 0, (99.7% identity in 349 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the PhoH family. Note that previously known as phoH.;UniProt_AC=Q49751;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	872009	873658	.	-	0	Locus=ML0731c;Name=accD5;Function=;Product=Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE);Comments=ML0731c, len: 549 aa. Probable accD5, propyonyl-CoA carboxylase beta chain 5 (EC 6.4.1.3), highly similar to Rv3280|MTCY71.20|P96885|Z92771 accD5, propyonyl-CoA carboxylase beta chain 5 from Mycobacterium tuberculosis (548 aa), fasta scores: E(): 0, (88.7% identity in 549 aa); and CAD95400|Mb3308 from M. bovis (548 aa). Also highly similar to others e.g. PCCB_SACER|P53003 pccB propionyl-CoA carboxylase beta chain from Saccharopolyspora erythraea (546 aa), fasta scores: E(): 3.2e-158, (69.1% identity in 530 aa); and O87201|DTSR2 DTSR2 PROTEIN INVOLVED IN GLUTAMATE PRODUCTION from Corynebacterium glutamicum (Brevibacterium flavum) (537 aa), FASTA scores: opt: 2604, E(): 5.9e-168, (72.71% identity in 537 aa overlap) (see Kimura et al., 1996). Also similar to ML0102 and ML1657 from M. leprae. Previously sequenced as PCCB_MYCLE|P53002. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. BELONGS TO THE ACCD/PCCB FAMILY.;UniProt_AC=P53002;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	935509	936801	.	-	0	Locus=ML0792c;Name=aroA;Function=INVOLVED IN THE BIOSYNTHESIS OF CHORISMATE WITHIN THE BIOSYNTHESIS OF AROMATIC AMINO ACIDS (THE SHIKIMATE PATHWAY). ACTS IN THE SIXTH STEP OF THIS PATHWAY. [CATALYTIC ACTIVITY: PHOSPHOENOLPYRUVATE + 3-PHOSPHOSHIKIMATE = ORTHOPHOSPHATE + O(5)-(1-CARBOXYVINYL)-3-PHOSPHOSHIKIMATE].;Product=probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS);Comments=ML0792c, len: 430 aa. Probable aroA, 3-phosphoshikimate 1-carboxyvinyl transferase (EC 2.5.1.19) (see citation below), highly similar to Rv3227|MTCY20B11.02|AROA_MYCTU|P22487 aroA, 3-phosphoshikimate 1-carboxyvinyl transferase from Mycobacterium tuberculosis (450 aa), fasta scores: E(): 2e-132, (79.0% identity in 428 aa); and CAD95348|Mb3256 from M. bovis (450 aa). Similar to several e.g. Q9K4A7|ARA2_STRCO 3-phosphoshikimate 1-carboxyvinyl transferase from Streptomyces coelicolor (438 aa), fasta scores: E(): 1.2e-69, (53.009% identity in 432 aa overlap). Contains Pfam match to entry PF00275 EPSP_syntase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). Contains PS00885 EPSP synthase signature 2. BELONGS TO THE EPSP SYNTHASE FAMILY.;UniProt_AC=Q9CCI3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	523804	524289	.	-	0	Locus=ML0424c;Name=bcp;Function=;Product=Probable bacterioferritin comigratory protein Bcp;Comments=ML0424c, len: 161 aa. Probable bcp, bacterioferritin comigratory protein, highly similar to Rv2521|O5322|AL123456 bcp, bacterioferritin comigratory protein from M. tuberculosis (157 aa), Fasta scores: E(): 0, (79.6% identity in 157 aa overlap). Similar to many members of the AhpC/TSA family, suggesting a protective, antioxidant role. e.g. shows similarity to BAA90524|AB037598 prxQ, peroxiredoxin Q from Sedum lineare (186 aa), Fasta scores: E(): 3e-17, (40.0% identity in 155 aa overlap); P23480|BCP_ECOLI|B2480|BAB36765|Z3739|ECS3342 BACTERIOFERRITIN COMIGRATORY PROTEIN from Escherichia coli strain K12 (156 aa). Previously sequenced as O07705|Z97179 (161 aa), Fasta scores: E(): 0, (99.4% identity in 161 aa overlap). Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family.;UniProt_AC=O07705;Is_Pseudogene=No;Functional_Category=virulence, detoxification, adaptation
AL450380.2	Mycobrowser_v2	CDS	483452	485161	.	+	0	Locus=ML0389;Name=choD;Function=;Product=Probable cholesterol oxidase precursor ChoD (cholesterol-O2 oxidoreductase);Comments=ML0389, len: 569 aa. Probable choD, cholesterol oxidase precursor (EC 1.1.3.6), highly similar to Rv3409c|Q57307|Al123456 choD, putative cholesterol oxidase from M. tuberculosis (578 aa), Fasta scores: E(): 0, (88.6% identity in 569 aa overlap). Also similar to CHOD_STRSQ|P12676 choA, cholesterol oxidase precursor from Streptomyces sp. (strain SA-COO) (546 aa), Fasta scores: E(): 0.013, (26.6% identity in 561 aa overlap); and similar to other oxidoreductases e.g. Q9A7T6|CC1634 OXIDOREDUCTASE (GMC FAMILY) from Caulobacter crescentus (579 aa). Previously sequenced as Q59530|U00015 (585 aa), Fasta scores: E(): 0, (100.0% identity in 569 aa overlap).;UniProt_AC=Q9CCV1;Is_Pseudogene=No;Functional_Category=lipid metabolism
AL450380.2	Mycobrowser_v2	CDS	1170356	1170599	.	+	0	Locus=ML1000;Name=ML1000;Function=;Product=Putative ESAT-6 like protein (pseudogene);Comments=ML1000, len: 244 bp. Possible pseudogene similar to several M. tuberculosis putative ESAT-6 like proteins e.g. Rv2346, Rv1198, Rv3619 and Rv1037 etc (Best blastx scores: 132).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1506795	1507575	.	+	0	Locus=ML1262;Name=impA;Function=;Product=Probable inositol monophosphtase ImpA (pseudogene);Comments=ML1262, len: 781 bp. Possible pseudogene of M. tuberculosis orthologue impA|Rv1604 (813 bp) (Best blastx scores: 633).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	845461	846267	.	-	0	Locus=ML0707c;Name=deoD;Function=;Product=Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP);Comments=ML0707c, len: 268 aa. Probable deoD, purine nucleoside phosphorylase (EC 2.4.2.1), highly similar to PUNA_MYCTU|O53359|Rv3307 probable deoD purine nucleoside phosphorylase from M. tuberculosis (268 aa), Fasta scores: E(): 5.8e-81, (82.1% identity in 262 aa overlap). Similar to many others e.g. PUNA_BACST|P77834 deoD, purine nucleoside phosphorylase I from Bacillus stearothermophilus (274 aa), Fasta scores: E(): 6.5e-16, (43.1% identity in 246 aa overlap). Previously sequenced as PUNA_MYCLE|P46862 (268 aa), Fasta scores: E(): 0, (99.6% identity in 268 aa overlap). Contains Pfam match to entry PF00896 Mtap_PNP, phosphorylases family 2. Contains PS01240 Purine and other phosphorylases family 2 signature. BELONGS TO THE PNP/MTAP FAMILY 2 OF PHOSPHORYLASES.;UniProt_AC=P46862;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1498154	1498540	.	-	0	Locus=ML1253c;Name=glbO;Function=;Product=POSSIBLE GLOBIN (OXYGEN-BINDING PROTEIN) GLBO;Comments=ML1253c, len: 128 aa. Possible glbO, globin-like protein. Highly similar to putative globins from Mycobacterium tuberculosis Rv2470 TR:O53197 (EMBL:AL021246) (128 aa), Fasta scores: E(): 0, 88.7% identity in 124 aa overlap and Mycobacterium bovis TR:AAF36597 (EMBL:AF213450) (128 aa), Fasta scores: E(): 0, 88.7% identity in 124 aa overlap.;UniProt_AC=Q9CC59;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1367137	1367393	.	+	0	Locus=ML1169;Name=ML1169;Function=;Product=9.5 kDa culture filtrate antigen Cfp10A (pseudogene);Comments=ML1169, len: 257 bp. Possible pseudogene of M. tuberculosis orthologue Rv1335 (282 bp) (Best blastx scores: 114).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1527795	1528795	.	-	0	Locus=ML1283c;Name=cydB;Function=;Product=Probable integral membrane cytochrome D ubiquinol oxidase (subunit II) CydB  (pseudogene);Comments=ML1283c, len: 1001 bp. Possible pseudogene of M. tuberculosis orthologue cydB|Rv1622c (1041 bp) (Best blastx scores: 722).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	588044	589384	.	-	0	Locus=ML0485c;Name=gabT;Function=;Product=Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEMIALDEHYDE TRANSAMINASE) (GABA AMINOTRANSFERASE) (GABA-AT);Comments=ML0485c, len: 446 aa. Probable gabT, 4-aminobutyrate aminotransferase (EC 2.6.1.9), highly similar to GABT_MYCTU|Q50632|Rv2589 gabT, 4-aminobutyrate aminotransferase from M. tuberculosis (449 aa), Fasta scores: E(): 9.5e-157, (83.7% identity in 449 aa overlap); and CAD94805 4-aminobutyrate aminotransferase from M. bovis (449 aa), fasta scores:  E(): 9.5e-157, (83.742% identity in 449 aa overlap). Similar to many e.g. O86823|GABT from Streptomyces coelicolor (444 aa), FASTA scores: E(): 8.9e-111, (61.765% identity in 442 aa overlap); GABT_ECOLI|P22256 gabT, 4-aminobutyrate aminotransferase from Escherichia coli (426 aa), Fasta scores: E(): 0, (43.1% identity in 422 aa overlap). Also similar to ML1216, ML1409 and ML2414. Previously sequenced as GABT_MYCLE|P40829 (446 aa), Fasta scores: E(): 0, (99.8% identity in 446 aa overlap). Contains Pfam match to entry PF00202 aminotran_3, Aminotransferases class-III pyridoxal-phosphate. Contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferases. Cofactor: pyridoxal phosphate.;UniProt_AC=P40829;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	1181061	1181483	.	-	0	Locus=ML1011c;Name=ML1011c;Function=;Product=hypothetical protein;Comments=ML1011c, len: 140 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCB6;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1235301	1235648	.	-	0	Locus=ML1071c;Name=ML1071c;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML1071c, len: 348 bp. Possible pseudogene of M. tuberculosis orthologue Rv1216c (675 bp) (Best blastx scores: 244).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1530419	1531375	.	-	0	Locus=ML1285c;Name=cya;Function=;Product=Membrane anchored adenylyl cyclase Cya (pseudogene);Comments=ML1285c, len: 957 bp. Possible pseudogene of M. tuberculosis orthologue Rv1625c|cya (1332 bp) (Best blastx scores: 272).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	508756	509982	.	+	0	Locus=ML0411;Name=ML0411;Function=;Product=serine-rich antigen;Comments=ML0411, len: 408 aa. Member of the Mycobacteria PPE family. Similar to numerous M. tuberculosis PPE-family proteins e.g. Rv2108|P95315|AL123456 PPE-family protein (243 aa), Fasta scores: E(): 5.8e-17, (34.4% identity in 212 aa overlap). M. leprae serine-rich antigen (25L) (45 kDa protein). Also similar to ML0539, ML1182 and ML1991 from M. leprae. Previously sequenced as SRA_MYCLE|Q07297 (408 aa), Fasta scores: E(): 0, (100.0% identity in 408 aa overlap). Contains Pfam match to entry PF00823 PPE, PPE family.;UniProt_AC=Q07297;Is_Pseudogene=No;Functional_Category=PE/PPE
AL450380.2	Mycobrowser_v2	CDS	529521	530885	.	+	0	Locus=ML0430;Name=ML0430;Function=;Product=Probable conserved integral membrane leucine and alanine rich protein;Comments=ML0430, len: 454 aa. Probable conserved integral membrane leu-, ala-rich protein, highly similar to Rv2508c|O06171|AL123456 conserved integral membrane from M. tuberculosis (445 aa), Fasta scores: E(): 0, (75.7% identity in 441 aa overlap). Also similar to hypothetical or membrane proteins e.g. Q9RKX9|AL133213|SC6D7.19C putative integral membrane protein from Streptomyces coelicolor (486 aa), Fasta scores: E(): 1.5e-13, (29.7% identity in 445 aa overlap). Previously sequenced as O07710|Z97179 (464 aa), Fasta scores: E(): 0, (100.0% identity in 454 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CCU4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1716108	1716700	.	-	0	Locus=ML1429c;Name=ML1429c;Function=;Product=Probable alternative RNA polymerase sigma factor (pseudogene);Comments=ML1429c, len: 593 bp. Possible pseudogene similar to several M. tuberculosis sigma factors e.g. sig I|Rv1189, sig J|Rv3328c, sigE|Rv1221 and sigG|Rv0182c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	680811	681707	.	+	0	Locus=ML0563;Name=ML0563;Function=;Product=Conserved hypothetical protein;Comments=ML0563, len: 298 aa. Conserved hypothetical protein, highly similar to YE21_MYCTU|P71690|Rv1421 conserved hypothetical protein from M. tuberculosis (301 aa), Fasta scores: E(): 0, (92.3% identity in 285 aa overlap); and CAD94317|Mb1456 from M. bovis (301 aa). Conserved in other bacteria e.g. Q9Z513|YJ52_STRCO Hypothetical UPF0042 protein from Streptomyces coelicolor (299 aa), fasta scores: E(): 2.2e-62, (54.698% identity in 298 aa overlap). Contains a match to Pfam entry PF03668; ATP_bind2;1.;UniProt_AC=Q9CCP0;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1235877	1236695	.	-	0	Locus=ML1072c;Name=ML1072c;Function=;Product=Probable tetronasin-transport integral membrane ABC transporter (pseudogene);Comments=ML1072c, len: 819 bp. Possible pseudogene of M. tuberculosis orthologue Rv1217c (1647 bp) (Best blastx scores: 362).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	735003	736118	.	+	0	Locus=ML0603;Name=ML0603;Function=;Product=Probable lipoprotein;Comments=ML0603, len: 371 aa. Probable lipoprotein, highly similar but longer at the N-terminus to P71730|AL123456|Rv2413c conserved hypothetical protein from M. tuberculosis (316 aa), Fasta scores: E(): 0, (83.5% identity in 316 aa overlap); and CAD97297|Mb2436c from M. bovis (316 aa). Also similar to Q9RDM2|AL136518|SCC123.02C putative DNA-binding protein from Streptomyces coelicolor (336 aa), Fasta scores: E(): 0, (39.3% identity in 326 aa overlap). Previously sequenced as Q49756|U00016 (389 aa), Fasta scores: E(): 0, (100.0% identity in 371 aa overlap). Contains a possible N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.;UniProt_AC=O33133;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	772069	773490	.	-	0	Locus=ML0640c;Name=ML0640c;Function=;Product=Probable conserved ATP-binding protein ABC transporter;Comments=ML0640c, len: 473 aa. Probable conserved ATP-binding protein ABC transporter, highly similar to O53343|AL123456|Rv3197 conserved ATP-binding protein ABC transporter from M. tuberculosis (447 aa), Fasta scores: E(): 0, (83.0% identity in 447 aa overlap); and CAD95312|Mb3220 from M. bovis (447 aa). Similar to other proteins (generally ABC transporters) e.g. Q9FCJ6 Hypothetical protein SCO5192 from Streptomyces coelicolor (469 aa), fasta scores: opt: 1252, E(): 3.3e-72, (46.222% identity in 450 aa overlap). Also similar to ML1898. Previously sequenced as Q49747|U00016 (267 aa), Fasta scores: E(): 0, (99.6% identity in 248 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).;UniProt_AC=Q9CCM8;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	955684	955999	.	-	0	Locus=ML0807c;Name=ML0807c;Function=;Product=Possible acyltransferase (pseudogene);Comments=ML0807c, len: 316 bp. Possible pseudogene of M. tuberculosis orthologue Rv3216 (333 bp) (Best blastx scores: 171).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1717311	1718070	.	-	0	Locus=ML1431c;Name=ML1431c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1431c, len: 760 bp. Possible pseudogene of M. tuberculosis orthologue Rv2042c (798 bp) (Best blastx scores: 314).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	915870	916556	.	+	0	Locus=ML0773;Name=mtrA;Function=;Product=probable two-component sensory transduction transcriptional regulatory protein MtrA;Comments=ML0773, len: 228 aa. Probable mtrA, transcriptional activator, response regulator (see citations below), highly similar to Rv3246c|MTCY20B11.21c|Q50447|Z95121 mtrA, transcriptional activator from Mycobacterium tuberculosis (228 aa), fasta scores: E(): 1.3e-92, (98.7% identity in 228 aa); and CAD93364|Mb3274c from M. bovis (227 aa). Also highly similar to others e.g. AFQ1_STRCO|Q04942 transcriptional regulatory protein afsQ1 from Streptomyces coelicolor (225 aa), fasta scores: E(): 1.7e-40, (47.1% identity in 221 aa). Also similar to ML0174, ML1286, ML2123 and ML2439 from M. leprae. Contains Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal. Contains Pfam match to entry PF00072 response_reg, Response regulator receiver domain. SIMILAR TO BACTERIAL REGULATORY PROTEINS INVOLVED IN SIGNAL TRANSDUCTION. THE N-TERMINAL REGION IS SIMILAR TO THAT OF OTHER REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEMS. Experiments in M. tuberculosis have showed mtrA is differentially expressed in virulent and avirulent strains during growth in macrophages.;UniProt_AC=Q9CCJ2;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	943530	944970	.	-	0	Locus=ML0797c;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML0797c, len: 1440 bp. Possible pseudogene similar to several M. tuberculosis PPE-family proteins e.g. PPE23, PPE32, PPE14 PPE26 etc (Best blastx scores: 193).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	958212	958644	.	+	0	Locus=ML0809;Name=ML0809;Function=;Product=Possible soj/parA-related protein (pseudogene);Comments=ML0809, len: 432 bp. Possible pseudogene of M. tuberculosis orthologue Rv3213c (801 bp) (Best blastx scores: 239).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1026904	1027218	.	+	0	Locus=ML0863;Name=ML0863;Function=;Product=hypothetical protein;Comments=ML0863, len: 104 aa. Hypothetical unknown protein. Previously sequenced as O32957|Z98741.;UniProt_AC=O32957;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	598030	598917	.	-	0	Locus=ML0492c;Name=ppiB;Function=;Product=Probable peptidyl-prolyl cis-trans isomerase B PpiB (Cyclopphilin) (Ppiase) (Rotamase) (Peptidylprolyl isomerase);Comments=ML0492c, len: 295 aa. Probable ppiB, cyclophilin (peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8), highly similar to CYPB_MYCTU|Q50639|Rv2582 ppiB, probable peptidyl-prolyl cis-trans isomerase from M. tuberculosis (308 aa), Fasta scores: E(): 1.3e-79, (72.5% identity in 295 aa overlap); and CAD94798|Mb2613 from M. bovis (308 aa). Also similar to others e.g. Q9KJG8|PPIB PEPTIDYL-PROLYL CIS-TRANS ISOMERASE from Streptomyces lividans (277 aa), FASTA scores: E(): 4.1e-24, (40.268% identity in 298 aa overlap). Previously sequenced as CYPB_MYCLE|P46697 (295 aa), Fasta scores: E(): 0, (99.7% identity in 295 aa overlap).  Contains hydrophobic, possible membrane-spanning region. Alternatively, this may represent an N-terminal signal sequence, given the potential start codon at codon 33. Contains Pfam match to entry PF00160 pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase. Belongs to the cyclophilin-type Ppiase family.;UniProt_AC=P46697;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	664261	666216	.	+	0	Locus=ML0548;Name=priA;Function=RECOGNIZES A SPECIFIC HAIRPIN SEQUENCE ON PHIX SSDNA; THIS STRUCTURE IS THEN RECOGNIZED AND BOUND BY PROTEINS PRIB AND PRIC. FORMATION OF THE PRIMOSOME PROCEEDS WITH THE SUBSEQUENT ACTIONS OF DNAB, DNAC, DNAT AND PRIMASE. PRIA THEN FUNCTIONS AS A HELICASE WITHIN THE PRIMOSOME ;Product=Putative primosomal protein N' PriA (Replication factor Y).;Comments=ML0548, len: 651 aa. Putative priA, primosomal protein N', highly similar to PRIA_MYCTU|P71670|Rv1402 priA, putative primosomal protein N' from M. tuberculosis (655 aa), Fasta scores: E(): 0, (80.7% identity in 658 aa overlap); and CAD94298|Mb1437 from M. bovis (655 aa). Similar to many e.g. PRIA_ECOLI|P17888 priA, primosomal protein N' from Escherichia coli (732 aa), Fasta scores: E(): 1.2e-16, (28.1% identity in 445 aa overlap). COMPARED TO OTHER BACTERIAL PRIA, IT HAS A VERY DIVERGENT HELICASE DOMAIN. Belongs to the helicase family. PriA subfamily.;UniProt_AC=Q9CCQ3;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1740102	1740488	.	-	0	Locus=ML1446c;Name=ML1446c;Function=;Product=conserved hypothetical protein;Comments=ML1446c, len: 128 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2061c TR:O86340 (EMBL:Z97984) (134 aa), Fasta scores: E(): 0, 70.2% identity in 131 aa overlap.;UniProt_AC=Q9CC02;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	676303	677610	.	+	0	Locus=ML0559;Name=ribA;Function=;Product=Probable riboflavin biosynthesis protein RibA : GTP cyclohydrolase II + 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase);Comments=ML0559, len: 435 aa. Probable ribA, Riboflavin biosynthesis protein (EC 3.5.4.25), highly similar to GCH2_MYCTU|P71684|Rv1415 ribA2, probable Riboflavin biosynthesis protein from M. tuberculosis (425 aa), Fasta scores: E(): 1.1e-171, (93.4% identity in 425 aa overlap); and CAD94311|Mb1450 from M. bovis (425 aa). Similar to many e.g. O24752|GCH2_CORAM Riboflavin biosynthesis protein ribA from Corynebacterium ammoniagenes (Brevibacterium ammoniagenes) (423 aa), fasta scores: E(): 3.2e-105, (60.775% identity in 413 aa overlap). Contains Pfam match to entry PF00926 DHBP_synthase, 3,4-dihydroxy-2-butanone 4-phosphate synthase. Contains Pfam match to entry PF00925 GTP_cyclohydro2, GTP cyclohydrolase II. IN THE N-TERMINAL SECTION; BELONGS TO THE DHBP SYNTHASE FAMILY. IN THE C-TERMINAL SECTION; BELONGS TO THE GTP CYCLOHYDROLASE II FAMILY.;UniProt_AC=Q9CCP4;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	955208	955729	.	+	0	Locus=ML0806;Name=ML0806;Function=;Product=probable conserved integral membrane protein;Comments=ML0806, len: 173 aa. Probable conserved integral membrane protein, highly similar but longer at the N terminus to Rv3217c|MTCY07D11.09|O05849|Z95120 conserved integral membrane protein from Mycobacterium tuberculosis (143 aa), fasta scores: E(): 1.3e-38, (77.1% identity in 140 aa); and CAD95335|Mb3243c from M. bovis (143 aa). Also similar to others e.g. Q9F3L9|2SC7G11.04 Putative integral membrane protein from Streptomyces coelicolor (152 aa), fasta scores: E(): 2.6e-05, (36.207% identity in 116 aa overlap). Contains hydrophobic, possible membrane-spanning regions.;UniProt_AC=Q9CCH6;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	961969	962655	.	+	0	Locus=ML0812;Name=ML0812;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0812, len: 687 bp. Possible pseudogene of M. tuberculosis orthologue Rv3210c (696 bp) (Best blastx scores: 523).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	968159	968447	.	-	0	Locus=ML0819c;Name=ML0819c;Function=;Product=Possible DNA-methyltransferase (pseudogene);Comments=ML0819c, len: 289 bp. Possible pseudogene of M. tuberculosis orthologue Rv3204 (306 bp) (Best blastx scores: 245).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	915145	915777	.	+	0	Locus=ML0772;Name=tmk;Function=;Product=probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK);Comments=ML0772, len: 210 aa. Probable tmk, thymidylate kinase (EC 2.7.4.9), highly similar to MTCY20B11|Rv3247c|O05891|Z95121 Probable tmk, thymidylate kinase from Mycobacterium tuberculosis (214 aa), fasta scores: E(): 0, (77.3% identity in 207 aa); and CAD95367| from M. bovis (214 aa). Also similar to other thymidylate kinases e.g. Q8NSC3 Thymidylate kinase from Corynebacterium glutamicum (Brevibacterium flavum) (203 aa), fasta scores: E(): 6.9e-29, (50.746% identity in 201 aa overlap); and KTHY_HUMAN|P23919 thymidylate kinase tymK from Homo sapiens  fasta scores: E(): 0.005, (29.1% identity in 196 aa). Contains Pfam match to entry PF02223 Thymidylate_kin, Thymidylate kinase. Contains PS01331 Thymidylate kinase signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. BELONGS TO THE THYMIDYLATE KINASE FAMILY.;UniProt_AC=Q9CCJ3;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	384334	385650	.	+	0	Locus=ML0302;Name=ML0302;Function=;Product=Possible conserved membrane protein (pseudogene);Comments=ML0302, len: 1316 bp. Possible pseudogene of M. tuberculosis orthologue Rv0412c (1320 bp) (Best blastx scores: 1672);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	969796	972902	.	+	0	Locus=ML0821;Name=ML0821;Function=;Product=Possible ATP-dependent DNA helicase (pseudogene);Comments=ML0821, len: 3107 bp. Possible pseudogene of M. tuberculosis orthologue Rv3202c (3168 bp) (Best blastx scores: 725).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	949528	950330	.	-	0	Locus=ML0800c;Name=ML0800c;Function=;Product=Probable iron-regulated short-chain dehydrogenase/reductase (pseudogene);Comments=ML0800c, len: 803 bp. Possible pseudogene of M. tuberculosis orthologue Rv3224 (849 bp) (Best blastx scores: 426).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	950850	951069	.	+	0	Locus=ML0801;Name=sigH;Function=;Product=Alternative RNA polymerase sigma factor (ECF subfamily) SigH (pseudogene);Comments=ML0801, len: 220 bp. Possible pseudogene of M. tuberculosis orthologue sigH|Rv3223c (651 bp) (Best blastx scores: 162).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	951242	951440	.	+	0	Locus=ML0801A;Name=ML0801A;Function=;Product=Possible anti-sigma factor (pseudogene);Comments=ML0801A, len: 199 bp. Possible pseudogene of M. tuberculosis orthologue Rv3221A (306 bp) (Best blastx scores: 176).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	951152	951388	.	+	0	Locus=ML0801A;Name=ML0801A;Function=;Product=Possible anti-sigma factor (pseudogene);Comments=ML0801A, len: 199 bp. Possible pseudogene of M. tuberculosis orthologue Rv3221A (306 bp) (Best blastx scores: 176).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	954250	955186	.	-	0	Locus=ML0805c;Name=ML0805c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0805c, len: 937 bp. Possible pseudogene of M. tuberculosis orthologue Rv3218 (966 bp) (Best blastx scores: 324).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1309377	1309920	.	-	0	Locus=ML1126c;Name=ML1126c;Function=;Product=Possible lipoprotein (pseudogene);Comments=ML1126c, len: 544 bp. Possible pseudogene similar to M. tuberculosis lpqQ|Rv0835 (645 bp) (Best blastx scores: 222).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	475772	476080	.	-	0	Locus=ML0382c;Name=whiB3;Function=;Product=Probable transcriptional regulatory protein WhiB-like WhiB3;Comments=ML0382c, len: 102 aa. Probable whiB3 (alternate gene name: whmB), WhiB-like regulatory protein (see citations below), highly similar to Rv3416|Q50710|AL123456 whiB3, WhiB-like regulatory protein from M. tuberculosis (102 aa), Fasta scores: E(): 0, (86.3% identity in 102 aa overlap). Similar to many e.g. O88103|AJ010601 whiD, developmental regulatory gene from Streptomyces coelicolor (112 aa), Fasta scores: E(): 1.1e-24, (61.8% identity in 102 aa overlap). Previously sequenced as Q49871|U00015 (102 aa), Fasta scores: E(): 0, (100.0% identity in 102 aa overlap). Also similar to ML0760, ML0804 and ML2307 from M.leprae. Contains Pfam entry to PF02467, Transcription factor WhiB.;UniProt_AC=Q49871;Is_Pseudogene=No;Functional_Category=regulatory proteins
AL450380.2	Mycobrowser_v2	CDS	1281254	1282169	.	-	0	Locus=ML1108c;Name=ML1108c;Function=;Product=Probable aminotransferase (pseudogene);Comments=ML1108c, len: 916 bp.  Possible pseudogene of M. tuberculosis orthologue Rv0075 (1173 bp) (Best blastx scores: 290).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1383638	1384716	.	-	0	Locus=ML1184c;Name=ML1184c;Function=;Product=Possible zinc-containing alcohol dehydrogenase nad dependent (pseudogene);Comments=ML1184c, len: 1079 bp. Possible pseudogene similar to M. tuberculosis paralogue adhB|Rv0761c  (Best blastx scores: 217) and also similar to adhD|Rv3086.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1384842	1385330	.	-	0	Locus=ML1185c;Name=ML1185c;Function=;Product=Probable cytochrome p450 (pseudogene);Comments=ML1185c, len: 489 bp. Possible pseudogene similar to several M. tuberculosis cytochrome p450 e.g. cyp126|Rv0778, cyp144|Rv1777, cyp140|Rv1880c etc (Best blastx scores: 111).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1414049	1414555	.	-	0	Locus=ML1196c;Name=ML1196c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1196c, len: 507 bp. Possible pseudogene similar to M. tuberculosis Rv3832c (576 bp) (Best blastx scores: 159).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1474994	1475164	.	-	0	Locus=ML1238c;Name=cyp139;Function=;Product=Probable cytochrome p450 Cyp139 (pseudogene);Comments=ML1238c, len: 171 bp. Possible pseudogene of M. tuberculosis orthologue Rv1666c|cyp139 (1293 bp) (Best blastx scores: 147).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1511584	1512033	.	-	0	Locus=ML1268c;Name=bcpB;Function=;Product=Probable peroxidoxin BcpB (pseudogene);Comments=ML1268c, len: 450 bp. Possible pseudogene of M. tuberculosis orthologue bcpB|Rv1608c (465 bp) (Best blastx scores: 328).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1523865	1524236	.	+	0	Locus=ML1280;Name=ML1280;Function=;Product=Short-chain alcohol dehydrogenase family (pseudogene);Comments=ML1280, len: 372 bp. Possible pseudogene similar to several M. tuberculosis short-chain alcohol dehydrogenases e.g. Rv0765c, Rv1865, Rv1050 and Rv3057 (Best blastx scores: 81).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1524339	1526032	.	-	0	Locus=ML1281c;Name=cydC;Function=;Product=Probable 'component linked with the assembly of cytochrome' transmembrane ATP-binding protein ABC transporter CydC (pseudogene);Comments=ML1281c, len: 1694 bp. Possible pseudogene of M. tuberculosis orthologue Rv1620c|cydC (1731 bp) (Best blastx scores: 430).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1470765	1473312	.	+	0	Locus=ML1235;Name=pks9;Function=;Product=Probable polyketide synthase Pks9 (pseudogene);Comments=ML1235, len: 2548 bp. Possible pseudogene of M. tuberculosis orthologue pks9|Rv1664 (3054 bp) (Best blastx scores: 267).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1346880	1348316	.	-	0	Locus=ML1152c;Name=alkA;Function=;Product=Probable regulatory protein AlkA (pseudogene);Comments=ML1152c, len: 1437 bp. Possible pseudogene of M. tuberculosis orthologue alkA|Rv1317c (1491 bp) (Best blastx scores: 233).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1348503	1349672	.	+	0	Locus=ML1153;Name=ML1153;Function=;Product=Possible oxidoreductase (pseudogene);Comments=ML1153, len: 1170 bp. Possible pseudogene similar to M. tuberculosis Rv0063 (1440 bp) (Best blastx scores: 343);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1747565	1747954	.	-	0	Locus=ML1453c;Name=ML1453c;Function=;Product=conserved hypothetical protein;Comments=ML1453c, len: 129 aa. Conserved hypothetical protein. Similar to a number of proteins of undefined function e.g. Mycobacterium tuberculosis Rv2420c TR:O86327 (EMBL:Z81368) (126 aa), Fasta scores: E(): 0, 87.0% identity in 123 aa overlap.;UniProt_AC=Q9CBZ9;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1327810	1328472	.	+	0	Locus=ML1136;Name=ML1136;Function=;Product=conserved hypothetical protein;Comments=ML1136, len: 220 aa. Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD01_MYCLE (P45831) (220 aa), Fasta scores: E(): 0, 99.5% identity in 220 aa overlap. Also highly similar to several other proteins of undefined function e.g. Mycobacterium tuberculosis Rv1301 SW:YD01_MYCTU (Q10618) (217 aa), Fasta scores: E(): 0, 83.3% identity in 215 aa overlap. Contains Pfam match to entry PF01300 Sua5_yciO_yrdC, SUA5/yciO/yrdC family. Contains PS01147 SUA5/yciO/yrdC family signature.;UniProt_AC=P45831;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	rRNA	1346189	1346304	.	+	0	Locus=MLP000018;Name=rrf;Function=;Product=;Comments=5S ribosomal RNA gene as assigned by Liesack W.C et al., (1991) FEBS Lett. 281:114-118;UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	972941	975901	.	+	0	Locus=ML0822;Name=ML0822;Function=;Product=Probable ATP-dependent DNA helicase (pseudogene);Comments=ML0822, len: 2961 bp. Possible pseudogene of M. tuberculosis orthologue Rv3201c (3306 bp) (Best blastx scores: 510);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	981139	981420	.	-	0	Locus=ML0827c;Name=ML0827c;Function=;Product=putative transposase (pseudogene);Comments=ML0827c, len: 282 bp. Possible pseudogene of a Tn3-type element transposase similar to Rv2355 Probable IS6110 transposase;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	rRNA	1341147	1342695	.	+	0	Locus=MLP000016;Name=rrs;Function=;Product=;Comments=16S ribosomal RNA gene. As assigned by Sela S., Clark-Curtiss J.E. Gene 98:123-127 (1991) (EMBL:M58020);UniProt_AC=;Is_Pseudogene=No;Functional_Category=stable RNAs
AL450380.2	Mycobrowser_v2	CDS	1518433	1518669	.	+	0	Locus=ML1275;Name=ML1275;Function=;Product=hypothetical protein;Comments=ML1275, len: 78 aa. Hypothetical unknown protein.;UniProt_AC=Q9CC51;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1092699	1093053	.	-	0	Locus=ML0924c;Name=ML0924c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0924c, len: 355 bp. Possible pseudogene of M. tuberculosis orthologue Rv2143 (1059 bp) (Best blastx scores: 106).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1115200	1116010	.	-	0	Locus=ML0945c;Name=bpoB;Function=;Product=Possible peroxidase BpoB (pseudogene);Comments=ML0945c, len: 811 bp. Possible pseudogene of M. tuberculosis orthologue bpoB|Rv1123c (909 bp) (Best blastx scores: 308).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1157916	1159290	.	-	0	Locus=ML0991c;Name=ML0991c;Function=;Product=Conserved hypothetical alanine and arginine rich protein (pseudogene);Comments=ML0991c, len: 1375 bp. Possible pseudogene of M. tuberculosis orthologue Rv2731 (1353 bp) (Best blastx scores: 491).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1188117	1188450	.	+	0	Locus=ML1020;Name=ML1020;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1020, len: 334 bp. Possible pseudogene of M. tuberculosis orthologue Rv2705c (390 bp) (Best blastx scores: 206).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1188443	1188861	.	-	0	Locus=ML1021c;Name=ML1021c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1021c, len: 419 bp. Possible pseudogene of M. tuberculosis orthologue Rv2704 (429 bp) (Best blastx scores: 153).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1212197	1212941	.	-	0	Locus=ML1047c;Name=ML1047c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1047c, len: 745 bp. Possible pseudogene similar to  M. tuberculosis Rv3714c (891 bp) (Best blastx scores: 211). Identical to ML1943 and similar to ML2328c possible pseudogenes similar to M. tuberculosis Rv3714c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1245747	1246195	.	-	0	Locus=ML1082c;Name=ML1082c;Function=;Product=Probable membrane protein (pseudogene);Comments=ML1082c, len: 449 bp. Possible pseudogene of M. tuberculosis orthologue Rv1231c (543 bp) (Best blastx scores: 179).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1246220	1246770	.	-	0	Locus=ML1083c;Name=ML1083c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1083c, len: 551 bp. Possible pseudogene of M. tuberculosis orthologue Rv1232c (1308 bp) (Best blastx scores: 228).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1285581	1286612	.	+	0	Locus=ML1111;Name=ML1111;Function=;Product=Adenylate cyclase (pseudogene);Comments=ML1111, len: 1032 bp. Possible pseudogene of M. tuberculosis orthologue Rv1264 (1194 bp) (Best blastx scores: 409).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1374950	1375678	.	+	0	Locus=ML1178;Name=fabG2;Function=;Product=Probable 3-oxoacyl-[ACP] reductase FabG2 (pseudogene);Comments=ML1178, len: 729 bp. Possible pseudogene of M. tuberculosis orthologue fabG2|Rv1350 (744 bp) (Best blastx scores: 176).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1377210	1378304	.	+	0	Locus=ML1179;Name=ML1179;Function=;Product=Probable acyl-CoA dehydrogenase (pseudogene);Comments=ML1179, len: 1095 bp. Possible pseudogene similar to M. tuberculosis FadE3|Rv0215c (1074 bp) (Best blastx scores: 329). Also similar to ML2626c a possible pseudogene similar to M. tuberculosis fadE3.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1528830	1530134	.	-	0	Locus=ML1284c;Name=cydA;Function=;Product=Probable integral membrane cytochrome D ubiquinol oxidase (subunit I) CydA (pseudogene);Comments=ML1284c, len: 1305 bp. Possible pseudogene of M. tuberculosis orthologue cydA|Rv1623c (1458 bp) (Best blastx scores: 1184).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1349726	1350955	.	-	0	Locus=ML1154c;Name=ML1154c;Function=;Product=Possible adenylate cyclase (pseudogene);Comments=ML1154c, len: 1230 bp. Possible pseudogene of M. tuberculosis orthologue Rv1318c (1626 bp) (Best blastx scores: 336) and similar to Rv1320c and Rv1319c. Also similar to ML0465 a possible pseudogene similar to M. tuberculosis Rv1318c.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1187213	1187428	.	-	0	Locus=ML1018c;Name=ML1018c;Function=;Product=hypothetical protein;Comments=ML1018c, len: 71 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCB3;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1280429	1280770	.	+	0	Locus=ML1106;Name=ML1106;Function=;Product=hypothetical protein;Comments=ML1106, len: 113 aa. Hypothetical unknown protein.;UniProt_AC=Q9CC90;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1338522	1338677	.	-	0	Locus=ML1148c;Name=ML1148c;Function=;Product=hypothetical protein;Comments=ML1148c, len: 51 aa. Hypothetical protein (doubtful CDS). Identical to the previously sequenced Q50137|U15186 Mycobacterium leprae (51 aa), Fasta scores: E(): 4.9e-22, 100.0% identity in 51 aa overlap.;UniProt_AC=Q50137;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1111591	1112383	.	-	0	Locus=ML0942c;Name=ML0942c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0942c, len: 793 bp. Possible pseudogene of M. tuberculosis orthologue Rv1118c (861 bp) (Best blastx scores: 257).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1048645	1050391	.	-	0	Locus=ML0884c;Name=ML0884c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0884c, len: 1747 bp. Possible pseudogene of M. tuberculosis orthologue Rv2191 (1938 bp) (Best blastx scores: 194).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1060121	1060874	.	+	0	Locus=ML0894;Name=ML0894;Function=;Product=Probable conserved integral membrane protein (pseudogene);Comments=ML0894, len: 754 bp. Possible pseudogene of M. tuberculosis orthologue Rv2180c (888 bp) (Best blastx scores: 217).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1177752	1178395	.	-	0	Locus=ML1007c;Name=ML1007c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1007c, len: 644 bp. Possible pseudogene of M. tuberculosis orthologue Rv2716 (687 bp) (Best blastx scores: 190).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1196611	1196937	.	+	0	Locus=ML1031;Name=ML1031;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1031, len: 327 bp. Possible pseudogene of M. tuberculosis orthologue Rv2694c (369 bp) (Best blastx scores: 124).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1197738	1198012	.	-	0	Locus=ML1033c;Name=ceoC;Function=;Product=TRK system potassium uptake protein CeoC (pseudogene);Comments=ML1033c, len: 275 bp. Possible pseudogene of M. tuberculosis orthologue ceoC|Rv2692 (663 bp) (Best blastx scores: 154).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1211369	1212075	.	+	0	Locus=ML1046;Name=ML1046;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1046, len: 707 bp. Possible pseudogene of M. tuberculosis orthologue Rv2675c (753 bp) (Best blastx scores: 246).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1287173	1287433	.	+	0	Locus=ML1112;Name=ML1112;Function=;Product=Hypothetical protein (pseudogene);Comments=ML1112, len: 261 bp. Possible pseudogene of M. tuberculosis orthologue Rv1265 (681 bp) (Best blastx scores: 242).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1293284	1294515	.	-	0	Locus=ML1118c;Name=ML1118c;Function=;Product=REP13E12-family protein (pseudogene);Comments=ML1118c, len: 1232 bp. Possible pseudogene similar to several  M. tuberculosis conserved hypothetical proteins in REP13E12 degenerate repeat e.g. Rv1128c, Rv1702c, Rv1945 and Rv1148 (Best blastx scores: 268).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1833937	1834663	.	+	0	Locus=ML1520;Name=ML1520;Function=;Product=Probable alanine rich hydrolase (pseudogene);Comments=ML1520, len: 727 bp. Possible pseudogene of M. tuberculosis orthologue Rv2765 (738 bp) (Best blastx scores: 188).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1180779	1181021	.	-	0	Locus=ML1010c;Name=ML1010c;Function=;Product=hypothetical protein;Comments=ML1010c, len: 80 aa. Hypothetical unknown protein.;UniProt_AC=Q9CCB7;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1222252	1222605	.	+	0	Locus=ML1057;Name=ML1057;Function=;Product=hypothetical protein;Comments=ML1057, len: 117 aa. Hypothetical unknown protein. Identical to the previously sequenced Q49947|U15180 M. leprae hypothetical protein (117 aa), Fasta scores: E(): 0, 99.1% identity in 117 aa overlap.;UniProt_AC=Q49947;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1292712	1293197	.	-	0	Locus=ML1117c;Name=ML1117c;Function=;Product=conserved hypothetical protein;Comments=ML1117c, len: 161 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis Rv1276c SW:YC76_MYCTU (Q11043) (158 aa), Fasta scores: E(): 0, 65.4% identity in 162 aa overlap.;UniProt_AC=Q9CC85;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1035618	1036259	.	-	0	Locus=ML0872c;Name=ML0872c;Function=;Product=POSSIBLE CONSERVED MEMBRANE PROTEIN;Comments=ML0872c, len: 213 aa. Possible conserved membrane protein. Similar to Mycobacterium tuberculosis hypothetical 24.4 kDa protein Rv2203 or MYCY190.14 SW:YM03_MYCTU (Q10392) (230 aa) fasta scores: E(): 0, 61.7% identity in 230 aa. Contains hydrophobic, possible membrane-spanning region. Start changed since first submission protein now longer;UniProt_AC=Q9CCF4;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	1004962	1005483	.	-	0	Locus=ML0846c;Name=ML0846c;Function=;Product=Probable conserved transmembrane ATP-binding protein ABC transporter (pseudogene);Comments=ML0846c, len: 522 bp. Possible pseudogene similar to M. tuberculosis Rv1747 (2598 bp) (Best blastx scores: 127).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	967175	968068	.	+	0	Locus=ML0818;Name=ML0818;Function=;Product=conserved hypothetical protein;Comments=ML0818, len: 297 aa. Conserved hypothetical protein.  Similar to Rv3205c|O05861|AL123456 M. tuberculosis conserved hypothetical protein  (292 aa), Fasta scores: E(): 0, 87.3% identity in 291 aa overlap.;UniProt_AC=Q9CCG7;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1072705	1073838	.	+	0	Locus=ML0907;Name=ML0907;Function=;Product=probable conserved membrane protein;Comments=ML0907, len: 377 aa. Probable conserved membrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69559 (EMBL:AL022602) (377 aa), Fasta scores: E(): 0, 100.0% identity in 377 aa overlap(EMBL:AL022602). Also highly similar to Mycobacterium tuberculosis TR:O06213 (EMBL:Z95388) (384 aa), Fasta scores: E(): 0, 62.2% identity in 397 aa overlap. Contains a possible membrane spanning hydrophobic domain and a possible coiled-coil between residues 155..168.;UniProt_AC=O69559;Is_Pseudogene=No;Functional_Category=cell wall and cell processes
AL450380.2	Mycobrowser_v2	CDS	982492	983342	.	+	0	Locus=ML0828;Name=PPE;Function=;Product=PPE-family protein (pseudogene);Comments=ML0828, len: 851 bp. Possible pseudogene of M. tuberculosis PPE-family protein PPE38|Rv2352c (1176 bp) (Best blastx scores: 102).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	983749	984270	.	+	0	Locus=ML0829;Name=plcA;Function=;Product=Probable membrane-associated phospholipase C 1 plcA (pseudogene);Comments=ML0829, len: 522 bp. Possible pseudogene of M. tuberculosis orthologue plcA|Rv2351c (Best blastx scores: 175) and similar to plcB and plcC.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	984299	986301	.	-	0	Locus=ML0830c;Name=ML0830c;Function=;Product=Possible conserved transmembrane protein (pseudogene);Comments=ML0830c, len: 2003 bp. Possible pseudogene of M. tuberculosis orthologue Rv2345 (1983 bp) (Best blastx scores: 503). Also similar to ML1265c a possible pseudogene similar to M. tuberculosis Rv2345;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	987877	988330	.	+	0	Locus=ML0832;Name=ML0832;Function=;Product=Probable periplasmic superoxide dismutase (Cu-Zn) (pseudogene);Comments=ML0832, len: 454 bp. Possible pseudogene similar to M. tuberculosis sodC|Rv0432 (723 bp) (Best blastx scores: 163).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	990967	992730	.	-	0	Locus=ML0835c;Name=mez;Function=;Product=Probable [NAD] dependent malate oxidoreductase Mez (pseudogene);Comments=ML0835c, len: 1764 bp. Possible pseudogene of M. tuberculosis orthologue mez|Rv2332 (1647 bp) (Best blastx scores: 299).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	993464	993730	.	+	0	Locus=ML0836;Name=ML0836;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0836, len: 267 bp. Possible pseudogene similar to bacterial hypothetical proteins e.g. TM0911|Q9X013|AE001755 from Thermotoga maritima.;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	960120	961754	.	-	0	Locus=ML0811c;Name=rhlE;Function=;Product=Probable ATP-dependent RNA helicase Rhle;Comments=ML0811c, len: 544 aa. Probable ATP-dependent RNA helicase. Similar to O05855|Z95120|Rv3211|MTCY07D11.15c Mycobacterium tuberculosis putative ATP-dependent RNA helicase (407 aa), fasta scores: E(): 0, 74.8% identity in 531 aa, and to DEAD_KLEPN|P33906 Klebsiella pneumoniae ATP-dependent RNA helicase deaD fasta scores: E(): 0, 43.2% identity in 380 aa. Contains Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00039 DEAD-box subfamily ATP-dependent helicases signature. SIMILAR TO DEAD/DEAH BOX HELICASE FAMILY AND SIMILAR TO HELICASE C-TERMINAL DOMAIN.;UniProt_AC=Q9CCH3;Is_Pseudogene=No;Functional_Category=information pathways
AL450380.2	Mycobrowser_v2	CDS	1001911	1002398	.	+	0	Locus=ML0843;Name=lppP;Function=;Product=Probable lipoprotein LppP (pseudogene);Comments=ML0843, len: 488 bp. Possible pseudogene of M. tuberculosis orthologue lppP|Rv2330c (528 bp) (Best blastx scores: 294).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1005525	1005851	.	-	0	Locus=ML0847c;Name=ML0847c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0847c, len: 327 bp. Possible pseudogene of M. tuberculosis orthologue Rv2327 (492 bp) (Best blastx scores: 184).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	997288	998592	.	-	0	Locus=ML0840c;Name=ML0840c;Function=;Product=hypothetical protein;Comments=ML0840c, len: 434 aa. Hypothetical unknown protein. Previously sequenced as O32977|Z98741.;UniProt_AC=O32977;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	990404	990706	.	-	0	Locus=ML0834c;Name=ML0834c;Function=;Product=conserved hypothetical protein;Comments=ML0834c, len: 100 aa. Conserved hypothetical protein. Similar to Rv2342|MTCY98.11|P95238|Z83860 Mycobacterium tuberculosis hypothetical protein (85 aa), fasta scores: E(): 3e-21, 76.9% identity in 78 aa and shows weak similarity to Streptomyces coelicolor putative secreted protein SCC24.32|CAB86126|AL163003 (108 aa) fasta scores: E(): 0.035, 30.5% identity in 95 aa.;UniProt_AC=Q9CCG1;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1004103	1004684	.	-	0	Locus=ML0845c;Name=ML0845c;Function=;Product=conserved hypothetical protein;Comments=ML0845c, len: 193 aa. Conserved hypothetical protein. Similar to part of some acyl-CoA oxidases e.g. O65201|AF057043 Arabidopsis thaliana acyl-CoA oxidase cx2 (692 aa), fasta scores: E(): 1.5e-06, (35.2% identity in 125 aa). Previously sequenced as O32973|Z98741) (193 aa), fasta scores: E(): 0, (99.5% identity in 193 aa).;UniProt_AC=O32973;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1033728	1035173	.	+	0	Locus=ML0870;Name=ML0870;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML0870, len: 1446 bp. Possible pseudogene of M. tuberculosis orthologue Rv2205c (1077 bp) (Best blastx scores: 131);UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2236227	2237470	.	-	0	Locus=ML1853c;Name=atsA;Function=;Product=Possible arylsulfatase AtsA (pseudogene);Comments=ML1853c, len: 1244 bp. Possible pseudogene of M. tuberculosis orthologue atsA|Rv0711 (2364 bp) (Best blastx scores: 344).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1020472	1021416	.	-	0	Locus=ML0858c;Name=lipA;Function=;Product=Probable lipoate biosynthesis protein A LipA;Comments=ML0858c, len: 314 aa. Probable lipA, lipoic acid synthetase. Similar to Mycobacterium tuberculosis lipoic acid synthetase lipA or Rv2218 or MTCY190.29 SW:LIPA_MYCTU (Q10380) (311 aa) fasta scores: E(): 0, 86.5% identity in 310 aa. Similar to many e.g. Escherichia coli lipoic acid synthetase lipA or lip SW:LIPA_ECOLI (P25845; P77595) (321 aa) fasta scores: E(): 0, 42.5% identity in 294 aa. Previously sequenced as SW:LIPA_MYCLE (O32962).;UniProt_AC=O32962;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration
AL450380.2	Mycobrowser_v2	CDS	2249977	2251056	.	-	0	Locus=ML1870c;Name=pqqE;Function=;Product=Probable coenzyme pqq synthesis protein E PqqE (pseudogene);Comments=ML1870c, len: 1080 bp. Possible pseudogene of M. tuberculosis orthologue pqqE|Rv0693 (1176 bp) (Best blastx scores: 555).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2138770	2138985	.	+	0	Locus=ML1763;Name=ML1763;Function=;Product=hypothetical protein;Comments=ML1763, len: 71 aa. Hypothetical unknown protein.;UniProt_AC=Q9CBN9;Is_Pseudogene=No;Functional_Category=unknown
AL450380.2	Mycobrowser_v2	CDS	1057488	1057880	.	+	0	Locus=ML0891;Name=ML0891;Function=;Product=conserved hypothetical protein;Comments=ML0891, len: 130 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2183c TR:O53517 (EMBL:AL021957) (131 aa), Fasta scores: E(): 1.3e-30, 62.6% identity in 131 aa overlap. Previously sequenced Mycobacterium leprae hypothetical protein TR:O69573 (EMBL:AL022602) (130 aa), Fasta scores: E(): 0, 100.0% identity in 130 aa overlap.;UniProt_AC=O69573;Is_Pseudogene=No;Functional_Category=conserved hypotheticals
AL450380.2	Mycobrowser_v2	CDS	1098590	1099189	.	+	0	Locus=ML0929;Name=mgtC;Function=;Product=Possible magnesium transport ATPase protein C MgtC (pseudogene);Comments=ML0929, len: 600 bp. Possible pseudogene of M. tuberculosis orthologue mgtC|Rv1811 (705 bp) (Best blastx scores: 171).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1099220	1100064	.	-	0	Locus=ML0930c;Name=ML0930c;Function=;Product=Probable dehydrogenase (pseudogene);Comments=ML0930c, len: 845 bp. Possible pseudogene of M. tuberculosis orthologue Rv1812c (1203 bp) (Best blastx scores: 260).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1100317	1101172	.	+	0	Locus=ML0931;Name=erg3;Function=;Product=Membrane-bound C-5 sterol desaturase Erg3 (pseudogene);Comments=ML0931, len: 856 bp. Possible pseudogene of M. tuberculosis orthologue Rv1814|erg3 (903 bp) (Best blastx scores: 379).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	2251136	2251396	.	-	0	Locus=ML1871c;Name=ML1871c;Function=;Product=Conserved hypothetical protein (pseudogene);Comments=ML1871c, len: 261 bp. Possible pseudogene of M. tuberculosis orthologue Rv0692 (330 bp) (Best blastx scores: 123).;UniProt_AC=;Is_Pseudogene=Yes;Functional_Category=pseudogenes
AL450380.2	Mycobrowser_v2	CDS	1045991	1046860	.	-	0	Locus=ML0881c;Name=qcrC;Function=;Product=Probable Ubiquinol-cytochrome C reductase QcrC (cytochrome C subunit);Comments=ML0881c, len: 289 aa. Probable qcrC, Ubiquinol-cytochrome C reductase. Similar to Mycobacterium tuberculosis ubiquinol-cytochrome C reductase cytochrome C subunit qcrC or Rv2194 or MTCY190.05 SW:QCRC_MYCTU (Q10386) (280 aa) fasta scores: E(): 0, 84.4% identity in 289 aa and to Streptomyces coelicolor cytochrome C heme-binding subunit SC6G10.23C TR:Q9X808 (EMBL:AL049497) (269 aa) fasta scores: E(): 0, 48.9% identity in 266 aa. Previously sequenced as SW:QCRC_MYCLE (O69583). Contains Pfam match to entry PF00034 cytochrome_c, Cytochrome c. Contains 2 x PS00190 Cytochrome C family heme-binding site signature. THE MAIN SUBUNITS OF THE UBIQUINOL:CYTOCHROME C COMPLEX ARE: CYTOCHROME B, THE RIESKE PROTEIN AND A CYTOCHROME C SUBUNIT.;UniProt_AC=O69583;Is_Pseudogene=No;Functional_Category=intermediary metabolism and respiration