Gene ML0042 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameeccE1
Gene length1404 bp
IdentifierML0042
Location 51993 bp
Protein summary information
Molecular mass51452.3 Da
Isoelectric point8.74
Protein length468 amino acids
Orthologs
M. tuberculosis H37RvRv3882c
M. lepromatosis Mx1-22AMLPM_0042
Cross-references
UniProtQ7AQP3
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductESX CONSERVED COMPONENT ECCE1. POSSIBLE MEMBRANE PROTEIN.
CommentsML0042, len: 467 aa. Possible conserved membrane protein, highly similar to Rv3882c|O05462|AL123456 conserved membrane protein from M. tuberculosis (462 aa), Fasta scores: E(): 0, (72.1% identity in 462 aa overlap). Shows weak similarity to O05459|AL123456 hypothetical protein from M.tuberculosis (537 aa), Fasta scores: E(): 3.1e-09, (28.0% identity in 382 aa overlap). Also shows weak similarity to ML1537. Previously sequenced as O33077|Y14967 (467 aa), Fasta scores: E(): 0, (100.0% identity in 467 aa overlap). Contains hydrophobic, possible membrane-spanning regions near the N-terminus.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS5199353396+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0042|eccE1
MRNPVWLRFSMGRALLVTALVPPCIILFFHTQYWWAGIALVVLVVILTLVEFSGRWLSGWLMALYSFFRRSSKPLDTPSEPVIGATVKPADQVIMRWQDGFLVSVVELIPRPFTPTVIVDGEAQTDDLLETQLLEHLLSVHCPDLEAVVVSAGYRVGHVASLDVVNLYQQVIGADPAPAHRRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDAVCGHSFESVDHATDVGFMQEKWSMMRGQNAYSVAYTAPAGPDAWWSARADHTITRVWVAPGKTPQATVVLTTLGKPKTPCGFYRLHGAQQPALLGRSFVAYQHCQMPIGSAGVLVGETVNRCSVYMPFDDVDVSVSLGDVQTFTQFVVRAAAAGGIVTLGQQFEKFARMIGGQIGSVAKVAWPNATTYLDPYPGSERVILKHDIIGTPRHRKLPIRRISPPEEGHYQMVLPKSSYEL
Bibliography