Gene ML0054c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameeccB1
Gene length1446 bp
IdentifierML0054c
Location 67417 bp
Protein summary information
Molecular mass51874.5 Da
Isoelectric point8.81
Protein length482 amino acids
Structural information
PFAMPF05108
Orthologues
M. tuberculosisRv3869
Cross-references
UniProtQ7AQN9
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductESX CONSERVED COMPONENT ECCB1. POSSIBLE MEMBRANE PROTEIN.
CommentsML0054c, len: 481 aa. esx conserved component, possible membrane protein, highly similar to several M. tuberculosis hypothetical proteins e.g. Rv3869|O69734|AL123456 conserved membrane protein (480 aa), Fasta scores: E(): 0, (75.7% identity in 478 aa overlap). Similar to ML1544 and ML2536 from M. leprae. Previously sequenced as O33088|Y14967 (481 aa), Fasta scores: E(): 0, (100.0% identity in 481 aa overlap). Contains hydrophobic, possible membrane-spanning region near the N-terminus.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS6741768862-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0054c|eccB1
MGLRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVALLIGAVLLAYFKPQGKLGASTLLTDRATNQLYVLLSGHLYPVYNLTSARLALGKPANPAAVKSSELTKLPIGQTIGIPGAPYATPVSGDSSSTWTLCDTVAKIESESPAVQTSVIARSLQIDPAINPLQPNEALLASYRDKTWLVNSKGRHSIDLADRALTSAIGISVNVKPTPLSEGLFNALPDVGRWELPTIPDTGAPNSLGLSPDLVIGSVFQIQMEKSPQYYVVLSDGIAQVNATTADALRATQSHGLVAPPSLVPNVVVQIPERVYDSPLPDEPLKMVARDDYPTLCWAWERKASDQAPKRTMLIGQHLPLQPSAMSTGIKQIRGTATVYIDGGRYVALQSPDPRYSESLYYVDPEGVRYGLANSEAVKALGLASPQTAPWVIVRLLVEGPVLSRDAALLEHDTLIADPSPRKVPAGYSGVRP
Bibliography