Gene ML0231 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepanD
Gene length429 bp
IdentifierML0231
Location 302404 bp
Protein summary information
Molecular mass15086.2 Da
Isoelectric point4.86
Protein length143 amino acids
Structural information
PFAMPF02261
Orthologs
M. tuberculosis H37RvRv3601c
M. lepromatosis Mx1-22AMLPM_0231
Cross-references
UniProtQ9CD57
Gene OntologyAspartate 1-decarboxylase activity, Binding, Cytoplasm, Pantothenate biosynthetic process, Alanine biosynthetic process
Enzyme Classification4.1.1.11
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable aspartate-1-decarboxylase precursor PanD (aspartate alpha-decarboxylase)
CommentsML0231, len: 142 aa. Probable panD, aspartate 1-decarboxylase (EC 4.1.1.11), highly similar to PAND_MYCTU|Z95557 panD, aspartate-1-decarboxylase from M. tuberculosis (139 aa), Fasta scores: E(): 0, (82.9% identity in 140 aa overlap); and to several others e.g. Q9X4N0|AF116184 panD, L-aspartate-alpha-decarboxylase precursor from Corynebacterium glutamicum (136 aa), Fasta scores: E(): 9.3e-29, (68.8% identity in 128 aa overlap).
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS302404302832+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0231|panD
MLRTMLKSKIHRATVTQAYLHYVGSVTIDADLMGAADLLEGEQVTIVDINNGARLVTYAIAGERGTGVIGINGAAAHLVHPGDLVILISYGTMEDAEAHAYQPRIVFVDADNKPIDLGHDPGSVPLDISVAAELFDPRIGAR
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