Gene ML0236c
in Mycobacterium leprae TN
General annotation
Type | CDS |
Function | Unknown |
Product | Probable para-aminobenzoate synthase component I PabB |
Comments | ML0236c, len: 418 aa. Probable pabB, para-aminobenzoate synthase component I (EC 4.1.3.-), highly similar to Rv1005c|O05591|Z94752 pabB, putative para-aminobenzoate synthase component I from M. tuberculosis (458 aa), Fasta scores: E(): 0, (79.1% identity in 412 aa overlap). Similar to many others e.g. PABB_ECOLI|P05041 pabB, para-aminobenzoate synthase component I from Escherichia coli (453 aa), Fasta scores: E(): 5.5e-31, (35.2% identity in 378 aa overlap). Also similar to the C-terminal halves of ML0808 and ML1269 from M. leprae. When compared to the predicted M. tuberculosis translation, this CDS is missing the N-terminal 30 aa, thus it may be a pseudogene. Contains Pfam match to entry PF00425 chorismate_bind, chorismate binding enzyme. |
Functional category | Intermediary metabolism and respiration |
Coordinates
Type | Start | End | Orientation |
---|---|---|---|
CDS | 309643 | 310899 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0236c|pabB VRIERLGNLGDAPRVLRSLGDATTGLDLPPPAALTGEWFDALAIIAPSLSVQPVDVNDAFAVQLDARTPDSAVAVGGGWVGYLSYPDPAADKQPNRIPEAAGGWTDCVLRRDRGAQWWYESLSGAPMPGWLAAALATTPAPARNCQVDWERTDWGAHRDGVLACLEAIRAGEIYQACVCTQFTGTVTGAPLDFFIAVVARTAPARAAYIAGPWGAVASLSPELFLRRRGAGVTSSPIKGTLPLAAWPSALQASAKEVAENIMIVDLVRNDLGRVAITGTVTVPELLVVRHAPGVWHLVSTVTAQVPVELPMAALLDATFPPASITGTPKLRARKLISQWEHRRRGIYCGTVGLASPIAGCELNVAIRTVEFDTAGNAVLGVGGGITADSDPDAELQECLHKAAPILRLASVATVASVG
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