Gene ML0241 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameksgA
Gene length921 bp
IdentifierML0241
Location 316048 bp
Protein summary information
Molecular mass33884.7 Da
Isoelectric point10.25
Protein length307 amino acids
Structural information
PFAMPF00398
Orthologs
M. tuberculosis H37RvRv1010
M. lepromatosis Mx1-22AMLPM_0241
Cross-references
UniProtQ9CD52
Gene OntologyRrna (adenine-n6,n6-)-dimethyltransferase activity, Rrna modification, Response to antibiotic, Rna binding
Enzyme Classification2.1.1.-
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable dimethyladenosine transferase KsgA (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (16S rRNA dimethylase) (High level kasugamycin resistance protein ksgA) (Kasugamycin dimethyltransferase)
CommentsML0241, len: 306 aa. Probable ksgA, dimethyladenosine transferase (EC 2.1.1.-), highly similar to Rv1010|O05595|AL123456 ksgA, dimethyladenosine transferase from M. tuberculosis (317 aa), Fasta scores: E(): 0, (85.0% identity in 294 aa overlap). Similar to many e.g. KSGA_ECOLI|M68521 ksgA, dimethyladenosine transferase from Escherichia coli (273 aa), Fasta scores: E(): 8.3e-23, (33.7% identity in 261 aa overlap). Contains Pfam match to entry PF00398 RrnaAD, Ribosomal RNA adenine dimethylases. Contains PS01131 Ribosomal RNA adenine dimethylases signature.
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS316048316968+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0241|ksgA
VQRKSGCTLTIRLLERTEIRWLVKELECRPRKSLGQNFVHDANTVRRVVSTSRVNRSDFVLEVGPGFGSLTLALLDCGAAVSAIEIDPVLAGRLPQTVAEHSNNEIHRLTVCNRDVLSFRRGDLATEPTALVANLPYNVAVPALLHLLAEFPSIRTVTVMVQAEVAERLAAEPGGKDYGVPSVKLSFFGRVRRCGMVSPTVFWPIPRVYSGLVRVDRYATSPWPTDDAFRRQVFELVDIAFTQRRKTSRNAFVKWAGSSNESANRLLAASIDPARRGETLSIDDFVRLLRRSDGRDDAAVRSASAS
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