Gene ML0243
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Putative polyketide synthetase Pks16 |
| Comments | ML0243, len: 544 aa. Putative pks16, polyketide synthase, highly similar to Rv1013|O05598|AL123456 putative pks16, polyketide synthases from M. tuberculosis (544 aa), Fasta scores: E(): 0, (82.2% identity in 544 aa overlap); and other M. tuberculosis putative acyl-CoA synthases e.g. fadD33|Rv1345 (521 aa), fadD26|Rv2930 (583 aa). Similar to domains of other polyketide synthases e.g. Q9R9J1|AF184956 mycA, mycosubtilin synthetase from Bacillus subtilis (3971 aa), Fasta scores: E(): 0, (33.7% identity in 404 aa overlap). Also similar to ML0887, ML0100, ML0132, ML0138, ML1051, ML1234, ML1994, ML2358 and ML2546 from M. leprae. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature. |
| Functional category | Lipid metabolism |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 318220 | 319854 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0243|pks16
VSKFTEKMFRNARESSKGIVTGEPHNPVRHTWGQVHERASRIAGGLAGVGVGHGDAVGVLVGVPVEIAPTAQGLWMRGASLTMLHQPTPRTDLAVWEEDTTTVIDMIEAKAVIISDPFMAVAPILEARGVKVVTVEQLLAADPVDPIETDEDDLALMQLTSGSTGSPKAVQITHRNVYSNVEAMFIGVRYNVEKDVMISWLPCFHDMGMIGFLTVPMYFGAELVKVTPIDFLRDTLLWAKLIDKYKGTVICGPNFAYSLFTKRLRKQAKPGQFDLSTLRIAMSGAEPVDPADVEDLIDAGRPFGFRPEAILPAYGMAETTLAVSFSPVGEGLLVDEVDADLLAALRRAVPATKGNIRRLVSLGPLLDGLEVRIVDEDGNVLPSRGVGVIELRGESLTPGYITMGGFISAQDEHGWYDTGDLGYQMENGHIVVCGRVKDVIIMAGRNVYPTDIERAAGRVDGVRPGCAVAVRLDAGHSRETFAVAVESNAFEDTAEVRRIEHQVAHEVLKEVDVRPRNVVVLGPGTIPKTPSGKLRRASSVTLVT
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