Gene ML0244c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepth
Gene length600 bp
IdentifierML0244c
Location 319965 bp
Protein summary information
Molecular mass21405.6 Da
Isoelectric point10.35
Protein length200 amino acids
Structural information
PFAMPF01195
Orthologs
M. tuberculosis H37RvRv1014c
M. lepromatosis Mx1-22AMLPM_0244
Cross-references
UniProtQ9CD49
Gene OntologyCytoplasm, Translation, Aminoacyl-trna hydrolase activity
Enzyme Classification3.1.1.29
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable peptidyl-tRNA hydrolase Pth
CommentsML0244c, len: 199 aa. Probable pth, peptidyl-tRNA hydrolase (EC 3.1.1.29), highly similar to Rv1014c|PTH_MYCTU|P96386 pth, peptidyl-tRNA hydrolase from M. tuberculosis (191 aa), Fasta scores: E(): 0, (77.7% identity in 188 aa overlap). Similar to many e.g. PTH_ECOLI|P23932 pth, peptidyl-tRNA hydrolase from Escherichia coli (194 aa), Fasta scores: E(): 3.7e-22, (37.2% identity in 188 aa overlap). Contains Pfam match to entry PF01195 Pept_tRNA_hydro, Peptidyl-tRNA hydrolase. Contains PS01196 Peptidyl-tRNA hydrolase signature 2. Belongs to the Pth family.
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS319965320564-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0244c|pth
VAEPTLASGWYPRLVVGLGNPGKNYGRTRHNVGFMVANLLAVRLGSKFEVHKRSGADVVNGRLAGCSMLVAKPRNYMNESGQQVGLLAKLYSVTPADIIIVHDDLDLDFGRIRLKLGGGEGGHNGLRSVAAALGTKDFQRVRIGIGRPTGRKDPASFVLENFTTAERMQVPTICKRAADATELLVGLGLEPAQNHVHAW
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