Gene ML0249c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameglmU
Gene length1479 bp
IdentifierML0249c
Location 324556 bp
Protein summary information
Molecular mass51957.5 Da
Isoelectric point6.97
Protein length493 amino acids
Structural information
PFAMPF00132, PF01128
Orthologs
M. tuberculosis H37RvRv1018c
M. lepromatosis Mx1-22AMLPM_0249
Cross-references
UniProtQ9CD44
Gene OntologyCell morphogenesis, GO:0007047, Cytoplasm, Glucosamine-1-phosphate n-acetyltransferase activity, Isoprenoid biosynthetic process, Lipopolysaccharide biosynthetic process, Magnesium ion binding, Peptidoglycan biosynthetic process, Regulation of cell shape, Udp-n-acetylglucosamine diphosphorylase activity
Enzyme Classification 2.3.1.157, 2.7.7.23
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable UDP-N-acetylglucosamine pyrophosphorylase GlmU
CommentsML0249c, len: 492 aa. Probable glmU, UDP-n-acetylglucosamine pyrophosphorylase (EC 2.7.7.23), highly similar to Rv1018c|P96382|AL123456 glmU, probable UDP-N-acetylglucosamine pyrophosphorylase from M. tuberculosis (495 aa), Fasta scores: E(): 0, (82.1% identity in 492 aa overlap). Similar to many others e.g. GLMU_NEIGO|Q50986 glmU, UDP-N-acetylglucosamine pyrophosphorylase from Neisseria gonorrhoeae (456 aa), Fasta scores: E(): 0, (37.4% identity in 462 aa overlap). Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase. Contains 5 Pfam matches to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats).
Functional categoryCell wall and cell processes
Coordinates
TypeStartEndOrientation
CDS324556326034-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0249c|glmU
MTFRGDTAVLVLAAGPGSRMRSDTPKVLHTIAGRSMLSHSLHAITKLAPQHLVVVLGHEHQRIAPLVAELADTLERTIDVALQDRPRGTGHAVFCGLSALPDDYGGIVVVTSGDTPLLDANTLAELIATHNATSAAVTVLTTTFSDPLGYGRILRTQDNEVMAIIEHADASPSQREIREVNAGVYAFDITALRSALIRLNSNNTQQELYLTDVISILRREGQKVNAQHIDDNALVAGVNNRVQLAELSAELNRRIVATHQVAGVTIIDPATTWIDIDVTIGNDTVIHPGTQLLGRTQIGECCVIGPDTTLTDVLVSQRATVVRTHGTSSTIGAGAMVGPFTYLRPGTVLGTKGKLGAFVETKNSTIGTGAKVPHLTYVGDADIGEHSNIGASSVFVNYDGTAKQRTTIGSHVRTGSDTKFVAPVTVGDGAYTGAGTVVRNDVPPGALAVSVSPQRNIENWVQRKRPGSAAAQAAEKASTRTGKQSQQKSEPD
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