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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable F420-dependent glucose-6-phosphate dehydrogenase Fgd1
CommentsML0269c, len: 336 aa. Probable fgd1, F420-dependent glucose-6-phosphate dehydrogenase (EC 1.-.-.-), highly similar to others from Mycobacteria e.g. Rv0407|P96253|AL123456 from M. tuberculosis (336 aa), Fasta scores: E(): 0, (89.3% identity in 336 aa overlap); and Q9XC15|AF152394 from Mycobacterium avium (336 aa), Fasta scores: E(): 0, (88.4% identity in 336 aa overlap). And similar to other dehydrogenases e.g. putative dehydrogenase from Streptomyces coelicolor A3(2) (325 aa). Previously sequenced as O69589|AL023514 (336 aa), Fasta scores: E(): 0, (100.0% identity in 336 aa overlap). Also shows weak similarity to ML0131 from M. leprae. Note that previously known as fgd.
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS353007354017-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0269c|fgd1
MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPWRHQGGHASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWRGDRVDFDGDYYQLKGASIYDVPEGGVPIYIAAGGPEVAKYAGRAGEGFVCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSDPDEAVARVGQYVTWGLNHLVFHAPGHNQRRFLELFEKDLAPRLRRLG
      
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