Gene ML0270 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0270
Gene length756 bp
IdentifierML0270
Location 354105 bp
Protein summary information
Molecular mass27052.8 Da
Isoelectric point7.11
Protein length252 amino acids
Structural information
PFAMPF00753
Orthologs
M. tuberculosis H37RvRv0406c
M. lepromatosis Mx1-22AMLPM_0270
Cross-references
UniProtQ7AQK7
Gene OntologyHydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductBeta-lactamase-like protein
CommentsML0270, len: 251 aa. Beta-lactamase-like protein, highly similar to others from Mycobacteria e.g. Rv0406c|O86336|AL123456 Beta-lactamase-like protein from M. tuberculosis (272 aa), Fasta scores: E(): 0, (74.9% identity in 243 aa overlap); Q9XC16|AF152394 bllP, beta-lactamase-like protein from Mycobacterium avium (247 aa), Fasta scores: E(): 0, (73.7% identity in 243 aa overlap). Shows similarity to other members of the metallo-beta-lactamase superfamily. Previously sequenced as O69590|AL023514 (251 aa), Fasta scores: E(): 0, (100.0% identity in 251 aa overlap). Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily.
Functional categoryConserved hypotheticals
Coordinates
TypeStartEndOrientation
CDS354105354860+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0270|ML0270
MAAATLFQVTDSVHFARGDAVNWALVADDTGVMLIDTGYPGDRDDVVASLRQLGYEAGDVRAILLTHAHIDHMGSAIWFASKHRTPVYCHADEVGHTKREYLEQVSLLNIAMRVWQPRWAIWSGHVLRSGGLIRGGIPTAQPLTAETAAGLPGHPMAIFTPGHTGGHCSYVVDGVLISGDALITGHPLLRHRGPQLLTAVFSHSQKQCLRSLDALGLLETRILAPGHGELWHGPIREATEAALKQAGALTR
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