Gene ML0280c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable adenylosuccinate synthase PurA (IMP--aspartate ligase) (AdSS) (AMPSase) |
| Comments | ML0280c, len: 432 aa. Probable purA, adenylosuccinate synthase (EC 6.3.4.4), highly similar to Rv0357c|PURA_MYCTU|O08381 purA, adenylosuccinate synthase from M. tuberculosis (432 aa), Fasta scores: E(): 0, (87.9% identity in 431 aa overlap). Similar to many others e.g. PURA_ECOLI|P12283 purA, adenylosuccinate synthase from Escherichia coli (431 aa), Fasta scores: E(): 0, (51.1% identity in 425 aa overlap). Previously sequenced as PURA_MYCLE|O69595 (432 aa), Fasta scores: E(): 0, (100.0% identity in 432 aa overlap). Contains Pfam match to entry PF00709 Adenylsucc_synt, Adenylosuccinate synthetase. Contains PS00513 Adenylosuccinate synthetase active site. Contains PS01266 Adenylosuccinate synthetase GTP-binding site. Belongs to the adenylosuccinate synthetase family. |
| Functional category | Intermediary metabolism and respiration |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 361950 | 363248 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0280c|purA
MPAVVLIGAQWGDEGKGKVTDLLGGRAQWVVRYQGGNNAGHTVVLPTGENFTLHLIPSGVLTPGVTNVIGNGVVVDPGVLLSELQGLEDRGVDTSQLLISADAHLLMPYHVAIDKVTERYMGNKKIGTTGRGIGPCYQDKIARMGIRVADVLEPGELTHKIEAALEFKNQVLVKIYNRKALDLAQVVETLLEQAQQFRHRITDTRLLLNDALEAGETVLLEGAQGTLLDVDHGTYPYVTSSNPTAGGAALGSGIGPTRIHTVLGILKAYTTRVGSGPFPTELFDENGEYLAKTGSEIGVTTGRRRRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPVCVGYQIAGVRTHDMPITQSDLARAEPIYEELPGWWEDISGAREFEDLPAKARDYVLRLEELAGAQVACIGVGPGRDQTIVRCDVLRSRR
Bibliography
No article yet recorded
