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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable fructose bisphosphate aldolase Fba
CommentsML0286c, len: 345 aa. Probable fba (alternate gene name: fda), fructose bisphosphate aldolase (EC 4.1.2.13), highly similar to Rv0363c|ALF_MYCTU|O06313 fba, fructose bisphosphate aldolase from M. tuberculosis (344 aa), Fasta scores: E(): 0, (87.7% identity in 342 aa overlap). Similar to many e.g. ALF_CORGL|P19537 fructose bisphosphate aldolase from Corynebacterium glutamicum (343 aa), Fasta scores: E(): 0, (72.8% identity in 342 aa overlap). Previously sequenced as ALF_MYCLE|O69600 (345 aa), Fasta scores: E(): 0, (100.0% identity in 345 aa overlap). Contains Pfam match to entry PF01116 F_bP_aldolase, Fructose-bisphosphate aldolase class-II. Contains PS00806 Fructose-bisphosphate aldolase class-II signature 2. Contains PS00602 Fructose-bisphosphate aldolase class-II signature 1. Belongs to class II fructose-bisphosphate aldolase family. Cofactor: zinc.
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS367279368316-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0286c|fba
MPIATPEIYAEMLRRAKENSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFASGLGVKDMVTGAVALAKFTHTIAAKYPINVALHTDHCPKDKLDSYVRPLLAISARRVATGKDPLFGSHMWDGSAIPIDENLAIAQDLLKDAAAAKIILEVEIGVVGGEEDGVAGEINEKLYTTPKDFVKTIDALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAEGQKVAAAKLSQSEGSKPFDFVFHGGSGSEKSEIEEALRYGVVKMNVDTDTQYAFTRPVSGHMFTNYDGVLKVDGDVGNKKVYDPRSYLKKAEASMTERVLEACNDLRCAGKSVAAS
      
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