Gene ML0299c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Possible thiamine biosynthesis oxidoreductase ThiO |
| Comments | ML0299c, len: 340 aa. Possible thiO, thiamine biosynthesis oxidoreductase (EC 1.-.-.-), highly similar to Rv0415|P96261|AL123456 possible thiO, thiamine biosynthesis oxidoreductase from M. tuberculosis (340 aa), Fasta scores: E(): 0, (82.0% identity in 338 aa overlap). Shows weak similarity to GLOX_BACSU|O31616 goxB, glycine oxidase from Bacillus subtilis (369 aa), Fasta scores: E(): 6.6e-10, (28.7% identity in 352 aa overlap). Previously sequenced as Q9ZBL4|AL035159 (340 aa), Fasta scores: E(): 0, (100.0% identity in 340 aa overlap). Also shows weak similarity to ML2011 from M. leprae. Contains Pfam match to entry PF01266 DAO, D-amino acid oxidase. |
| Functional category | Intermediary metabolism and respiration |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 381655 | 382677 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0299c|thiO
MPSGPPAGSLAVIGGGVIGLSVARRAVQAGWSVRVHRTHEQGASWVAGGMLAPHSEGRPGEEQLLQLGLRSLRLWHEGGFTDRLAPEVITARESLVVAVDQADVADLRTVADWLSTQGHPVIWESAARDIEPLLAQGIRHGFWAPNELAVDNRALLAGLCLDCERLGVRWASPVNDLSCVNADAVVIANGIGAPALWPGLPVRPVKGEVLRLRWRNGCMSLLKRLIRAHVHGRQVYLVPRADGVVVGATQYEHGYDTAPVVSGVRDLLDDACAVLPTLGEYELAECAAGLRPTTPNNLPLVHRLDNRTLVAAGHGRSGFLLAPWTAEQIMFELAAVGAQA
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