Gene ML0310c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable CDP-diacylglycerol-serine o-phosphatidyltransferase PssA (Phosphatidylserine synthase) (PS synthase) |
| Comments | ML0310c, len: 300 aa. Probable pssA, PS synthase (CDP-diacylglycerol--serine O-phosphatidyltransferase) (EC 2.7.8.8) (see citation below), integral membrane protein, highly similar to Rv0436c|PSS_MYCTU|P96282 pssA, PS synthase (CDP-diacylglycerol--serine O-phosphatidyltransferase) from M. tuberculosis (286 aa), Fasta scores: E(): 0, (77.9% identity in 285 aa overlap). Similar to many others e.g. PSS_HELPY|Q48269 pssA, CDP-diacylglycerol-serine o-phosphatidyltransferase from Helicobacter pylori (237 aa), Fasta scores: E(): 2.3e-14, (34.6% identity in 234 aa overlap). Previously sequenced as Q9ZBM2|AL035159 (300 aa), Fasta scores: E(): 0, (100.0% identity in 300 aa overlap). Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. Contains PS00379 CDP-alcohol phosphatidyltransferases signature. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 397047 | 397949 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0310c|pssA
MTSRPRSRRAVNLQILPSSMTVLSICAGLTSIRFALEHQPKAAIALIAAAAILDGLDGRVARILGAESRMGEEIDSLADAVNFGVAPAVVLYATMLSTTPVGWVAVLLYPVCVVLRLARFNALLDDGTQPAYTREFFVGMPAPAGAVSVIGLLALKLQFGAGWWTSTWFLCIWVTGTSMLLISRIPMKKMHTVSVPPHYAAVFVAMLAIFAAAVVLAPYLLIWVIILTYLCHIPFAIHNQRWLAAHPEAWDDKFKQQHDARRAARRACPNRHAVPRLGLLKPGSRSMVRSGLRKPGRRFI
Bibliography
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