Gene ML0324 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0324
Gene length837 bp
IdentifierML0324
Location 413628 bp
Protein summary information
Molecular mass29557.6 Da
Isoelectric point8.27
Protein length279 amino acids
Structural information
PFAMPF00588, PF08032
Orthologs
M. tuberculosis H37RvRv3579c
M. lepromatosis Mx1-22AMLPM_0324
Cross-references
UniProtQ9CCW4
Gene OntologyRna methyltransferase activity, Rna processing, Rna binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPossible tRNA/rRNA methyltransferase
CommentsML0324, len: 278 aa. Possible tRNA/rRNA methyltransferase (EC 2.1.1.-), highly similar (longer 31 aa) to Rv3579c|P96861|AL123456 possible tRNA/rRNA methyltransferase from M. tuberculosis (322 aa), Fasta scores: E(): 0, (84.1% identity in 277 aa overlap). Similar to many hypothetical rRNA methyltransferases e.g. Q9L0Q5 putative tRNA/rRNA methyltransferase from Streptomyces coelicolor A3(2) (314 aa), Fasta scores: E(): 0, (54.5% identity in 288 aa overlap). Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS413628414464+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0324|ML0324
LEGRGPTPPAYLRPNHPAAKRNQSSPHRPVKRTDETETVLGRNPVLECLRAGVPATALYVALGTEVDKRLTESVMRAADVGVAILEVPRTYLDRITNNHLHQGIALQVPPYHYVHSDDLLAAATDSPPALLVALDNISDPRNLGAIVRSVAAFSGHGILIPQRRSASVTAVAWRTSAGAAARIPVARATNLTRALKVWADQGLRVIGLDHDGDTALDDLDGTDPLAVVVGSEGKGLSRLVRHSCDEVVSIPMAGQVESLNASVAVGVVLAEIARQRRL
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