Gene ML0373 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0373
Gene length1422 bp
IdentifierML0373
Location 465203 bp
Protein summary information
Molecular mass47226.9 Da
Isoelectric point6.17
Protein length474 amino acids
Structural information
PFAMPF01256, PF03853
Orthologs
M. tuberculosis H37RvRv3433c
M. lepromatosis Mx1-22AMLPM_0373
Cross-references
UniProtP37391
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductConserved hypothetical protein
CommentsML0373, len: 473 aa. Conserved hypothetical protein, highly similar to Rv3433c|YY33_MYCTU|O06250 conserved hypothetical protein from M. tuberculosis (473 aa), Fasta scores: E(): 0, (84.6% identity in 473 aa overlap). Similar to many bacterial hypothetical proteins e.g. O86783|SC6G4.20c from Streptomyces coelicolor (485 aa), Fasta scores: E(): 0, (49.1% identity in 489 aa overlap). Previously sequenced as YY33_MYCLE|P37391 (392 aa), Fasta scores: E(): 0, (94.5% identity in 381 aa overlap). Contains Pfam match to entry PF01256 UPF0031, Uncharacterized protein family UPF0031. Contains PS01049 Uncharacterized protein family UPF0031 signature 1. Contains PS01050 Uncharacterized protein family UPF0031 signature 2.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS465203466624+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0373|ML0373
MRHYYSVAAIRDAEASLLASLPDGVLMKRAAYGLASVIIRELAVRTGGVTGRRVCAVVGSGDNGGDALWAATFLRRRGAAADAVLLNPDRVHRKALVAFRKAGGRIVENVSAATDLVIDGVVGISGSGPLRPAAAAVFATVSASGVPVVAVDLPSGIDVVTGVINGPAVHAALTVTFGGLKPVHALADCGDVTLVDIGLDLPDSDILGLQAADVAAYWPVPGVHDDKYTQGVTGVLAGSSTYPGAAVLCTGAAVAATSGMVRYAGSAYTQVLAHWPEVIASATPTAAGRVQSWVVGPGLGIDATATAALWFALETDLPVLVDADGLTMLAAHPDLVINRNAPTVLTPHASEFARLAGTPPGDDRVGACRKLADSFGATVLLKGNVTVIADPGGPVYLNPAGQSWAATAGSGDVLSGMIGALLAAGLPAAEAAAAAAFVHARAAALSAADPGPGDVPTSASRMVSHIRTALAAL
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