Gene ML0379
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable O-sialoglycoprotein endopeptidase Gcp (Glycoprotease) |
| Comments | ML0379, len: 351 aa. Probable gcp, glycoprotease (EC 3.4.24.57), highly similar to Rv3419c|GCP_MYCTU|Q50709 gcp, probable O-sialoglycoprotein endopeptidase from M. tuberculosis (344 aa), Fasta scores: E(): 0, (86.1% identity in 345 aa overlap). Similar to other O-sialoglycoprotein endopeptidases e.g. GCP_PASHA|P36175 from Pasteurella haemolytica (325 aa), Fasta scores: E(): 0, (45.8% identity in 319 aa overlap); and O86793|GCP_STRCO|SC6G4.30 from Streptomyces coelicolor (374 aa). Previously sequenced as GCP_MYCLE|P37969 (351 aa), Fasta scores: E(): 0, (100.0% identity in 351 aa overlap). Contains Pfam match to entry PF00814 Peptidase_M22, Glycoprotease family. Contains PS01016 Glycoprotease family signature. Belongs to the Peptidase family M22; also known as the Glycoprotease family. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 471841 | 472896 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0379|gcp
MTISAVPGTIILAIETSCDETGVGIACLDDYGTVTLLADEVASSVDEQARFGGVVPEIASRAHLEALGPTIRCALAAAGLTGSAKPDVVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGGHTHLLQVRSLGAPIVELGSTVDDAAGEAYDKVARLLGLGYPGGKVLDDLARTGDRDAIVFPRGMTGPADDLNAFSFSGLKTAVARYVESHPDALPADVAAGFQEAVADVLTMKAVRAATGLGVSTLLIVGGVAANSRLRELAAQRCAAAGLMLRIPGPRFCTDNGAMIAAFAAHLLAAAAPPSPLDVPSDPGLPVVKRQIN
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