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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Product60 kDa chaperonin 1 GroEL1 (Protein Cpn60-1) (groEL protein 1)
CommentsML0381, len: 537 aa. groEL1 (alternate genbe name: cpn60_1), 60 kDa chaperonin 1 (protein cpn60 1) (see citations below), highly similar to Rv3417c|CH61_MYCTU|Q59573 groEL1, 60 kDa chaperonin 1 from M. tuberculosis (539 aa), Fasta scores: E(): 0, (82.9% identity in 539 aa overlap). Also highly similar to others e.g. P40171|CH61_STRCO|GROL1|GROEL1|SC6G4.40 from Streptomyces coelicolor (540 aa), Fasta scores: E(): 0, (82.9% identity in 539 aa overlap). Previously sequenced as CH61_MYCLE|P37578 (537 aa), Fasta scores: E(): 0, (100.0% identity in 537 aa overlap). Contains Pfam match to entry PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family. Contains PS00296 Chaperonins cpn60 signature. Belongs to the chaperonin (hsp60) family.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS473559475172+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0381|groEL1
MSKLIEYDETARHAMEVGMNKLADTVRVTLGPRGRHVVLAKAFGGPTITNDGVTVAREIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVKGGLRMVAAGANPVALGAGISKAADAVSEALLAVATPVAGKDAITQVATVSSRDEQIGALVGEGMNKVGTDGVVSVEESSTLDTELEFTEGVGFDKGFLSAYFVTDFDSQQAVLDDPLVLLHQEKISSLPELLPMLEKVTESGKPLLIVAEDLEGEALATLVVNSIRKTLKAVAVKSPFFGDRRKAFLEDLAIVTGGQVVNPETGLVLREVGTDVLGSARRVVVSKDDTIIVDGGGSNDAVAKRVNQLRAEIEVSDSEWDREKLQERVAKLAGGVAVIKVGAVTETALKKRKESVEDAVAAAKASIEEGIIAGGGSALVQCGAALKQLRTSLTGDEALGIDVFFEALKAPLYWIATNAGLDGAVVVDKVSGLPAGHGLNASTLGYGDLVADGVVDPVKVTRSAVLNAASVARMMLTTETAVVDKPAKTEEHDHHGHAH
      
Bibliography
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