Gene ML0411 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0411
Gene length1227 bp
IdentifierML0411
Location 508756 bp
Protein summary information
Molecular mass42466.2 Da
Isoelectric point4.01
Protein length409 amino acids
Structural information
PFAMPF00823
Cross-references
UniProtQ07297
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productserine-rich antigen
CommentsML0411, len: 408 aa. Member of the Mycobacteria PPE family. Similar to numerous M. tuberculosis PPE-family proteins e.g. Rv2108|P95315|AL123456 PPE-family protein (243 aa), Fasta scores: E(): 5.8e-17, (34.4% identity in 212 aa overlap). M. leprae serine-rich antigen (25L) (45 kDa protein). Also similar to ML0539, ML1182 and ML1991 from M. leprae. Previously sequenced as SRA_MYCLE|Q07297 (408 aa), Fasta scores: E(): 0, (100.0% identity in 408 aa overlap). Contains Pfam match to entry PF00823 PPE, PPE family.
Functional categoryPe/ppe
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS508756509982+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0411|ML0411
MFDFMVYSPEVNAFLMSRGPGSTPLWGAAEAWISLAEQLMEAAQEVSDTIVVAVPASFAGETSDMLASRVSTFVAWLDGNAENAGLIARVLHAVAYAFEEARAGMVPLLTVLGNIIHTMALKAINWFGQVSTTVAALEADYDLMWVQNSTAMTTYRDTVLRETGKMENFEPAPQLVSRYCMDRRDSVNSFHSSSSSDSLYESIDNLYDSVAQSEEHGSDSMSQSYNTCGSVAQSELCDSPFGTPSQSSQSNDLSATSLTQQLGGLDSIISSASASLLTTNSISSSTASSIMPIVASQVTETLGRSQVAVEKMIQSISSTAVSVDVAASKVVAGVGQAVSVGALRVPENWATASQPVMATAHSVPAGCSAITTAVSGPLEGVTQPAEEVLTASVAGGSGTGGPAFNEAV
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