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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPossible oxidoreductase
CommentsML0418, len: 210 aa. Possible oxidoreductase (EC 1.-.-.-), highly similar to Rv3368c|O50397|AL123456 possible oxidoreductase from M. tuberculosis (214 aa), Fasta scores: E(): 0, (81.9% identity in 210 aa overlap). Shows weak similarity NOX_THETH|X60110) nox, NADH dehydrogenase from Thermus aquaticus (205 aa), Fasta scores: E(): 0.00023, (28.8% identity in 212 aa overlap); and O30106|AF0131 putative NAD(P)H-flavin oxidoreductase from Archaeoglobus fulgidus (194 aa). Previously sequenced as O07697|Z97179 (210 aa), Fasta scores: E(): 0, (99.5% identity in 210 aa overlap). Also similar to ML2006 a possible pseudogene similar to M. tuberculosis Rv3368c. Contains Pfam match to entry PF00881 Nitroreductase, Nitroreductase family. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS517645518277+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0418|ML0418
LSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLQLALQAPTGSNSQGWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPEYPEGDTRGERMRLVRDSATYLAEHMHEVPVLLIPCLLGRAEESPLGAVSYWASLFPAVWSFCLALRSRGLGTCWTSLHLLGDGEQRAAEVLGIPSDKYSQGGLFPIAYTKGTDFRPANRLPAENVTHWDIW
      
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