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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable short-chain type dehydrogenase/reductase
CommentsML0429c, len: 268 aa. Probable ala-rich oxidoreductase, short-chain dehydrogenase/reductase (EC 1.-.-.-), highly similar to Rv2509|O06172|AL123456 putative ala-rich oxidoreductase from M. tuberculosis (268 aa), Fasta scores: E(): 0, (88.8% identity in 267 aa overlap). Similar to many putative dehydrogenases e.g O86553|SC1F2.16c putative dehydrogenase from Streptomyces coelicolor (276 aa), FASTA scores: opt: 492, E(): 9.5e-23, (38.15% identity in 262 aa overlap). Previously sequenced as O07709|Z97179 (268 aa), Fasta scores: E(): 0, (100.0% identity in 268 aa overlap). Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature. Belongs to the short-chain dehydrogenase/reductase (SDR) family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS528622529428-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0429c|ML0429c
MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDLAARLADKYRVAVEVRPADLTDPSERVKLADELTVRPISILCANAGTATFGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAATKAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDHDEASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSKAMSVASRYAPRAIVASIVGNFYKKLGGG
      
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