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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPossible pyridoxine biosynthesis protein SnzP
CommentsML0450c, len: 307 aa. Possible snzP, pyridoxine biosynthesis protein. Highly similar to Rv2606c|YQ06_MYCTU|O06208 snzP, pyridoxine biosynthesis protein from M. tuberculosis (299 aa), Fasta scores: E(): 0, (89.7% identity in 291 aa overlap). Highly conserved in both bacteria and eukaryotes. Highly similar to several pyridoxine biosynthesis proteins and hypothetical proteins e.g. Q9UW83|AF133101 pyroA, pyridoxine biosynthesis protein from Emericella nidulans (304 aa), Fasta scores: E(): 0, (65.9% identity in 299 aa overlap); and SCL2.13c conserved hypothetical protein from Streptomyces coelicolor A3(2) (303 aa). Previously sequenced as YQ06_MYCLE|O07145 (333 aa), Fasta scores: E(): 0, (100.0% identity in 307 aa overlap). Contains Pfam match to entry PF01680, SOR_SNZ family. Contains PS01235 Uncharacterized protein family UPF0019 signature. Belongs to the SOR_SNZ family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS550194551117-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0450c|snzP
VDSAAQSNQAQSVFGQTGTARVKRGMAEMLKGGVIMDVVIPEQARIAEGSGAVAVMALERVPSDIRAQGGVSRMSDPDMIESIIAAVTIPVMAKARIGHFVEAQILQSLGVDYIDESEVLTPADYTHHIDKWKFTVPFVCGATNLGEALRRINEGAAMIRSKGEAGTGDVSNATTHMRAIAGDIRRLTSLSEDELYVAAKELHAPYELVIEVARTNKLPVTLFTAGGIATPADAAMMMQLGAEGIFVGSGIFKSSDPAQRAAAIVKATTFYDDPDVLAKVSRGLGEAMAGIDVEQIAQPDRLAQRGW
      
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