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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable conserved membrane protein
CommentsML0451c, len: 349 aa. Probable conserved membrane protein, highly similar to Rv2609c|O06205|AL123456 conserved membrane protein from M. tuberculosis (351 aa), Fasta scores: E(): 0, (77.7% identity in 336 aa overlap). Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17|O69888|AL023797 (172 aa), Fasta scores: E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as O07146|Z96801 (349 aa), Fasta scores: E(): 0, (100.0% identity in 349 aa overlap); and Q9RYE5|DR0004 mutT/nudIX family protein from Deinococcus radiodurans (350 aa). Contains a possible N-terminal signal sequence. Contains PS00893 mutT domain signature. Belongs to the mutT/nudIX family.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS551192552241-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0451c|ML0451c
MLTLLVLLVALATLAGGWGYQTANRLNRLHVRYDLSWQALDGALARRAVVARAVAIDAYSGTSPGRRLAALADAAECAPRHTRENAENELSAALAMVDPASLPTALIAELADAEARVLLARRFHNDAVRDTLALGEQRLVRTLRLRGTASVPTYFEIVERPHALTHGDHGVPNQRTSARVVLLDETGAVLLLCGSDPAITNGHAPRWWITVGGEVRPGERLAAAAARELAEETGLRVIPTHMVGPIWRRDAIFEFNGSVIDSEEFYLVYRTRRFEPSTVGWTELEHLCLHGSRWCDANDIAELVASGEQVYPRQLGELLPVANQLADASTGTARGTAAARNTYVLLSIC
      
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