Gene ML0453c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable acyltransferase |
| Comments | ML0453c, len: 320 aa. Probable acyltransferase (EC 2.3.1.-), highly similar to Rv2611c|O06203|AL123456 probable acyltransferase from M. tuberculosis (316 aa), Fasta scores: E(): 0, (71.5% identity in 312 aa overlap); and Q9F7Y8 putative acyltransferase from Mycobacterium smegmatis (303 aa), Fasta scores: E(): 0, (67.8% identity in 301 aa overlap). Also similar to other acyltransferases e.g. Q9L283|SCL2.16c putative acyltransferase from Streptomyces coelicolor (311 aa), Fasta scores: E(): 7.4e-48 (48.0% identity in 302 aa overlap); and AAF31766|AF130984 lipid A biosynthesis acyltransferase from Campylobacter jejuni (295 aa), Fasta scores: E(): 0.00017, (20.0% identity in 180 aa overlap). Previously sequenced as O07148|Z96801 (320 aa), Fasta scores: E(): 0, (99.7% identity in 320 aa overlap). |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 553375 | 554337 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0453c|ML0453c
VTTSTAGLKMIRAPHRLMTGRAIDWAYAAGWRAVRAMPESAARFAFNTGARYAARNGGPDQLRKNLARIIGVQAADVPDALIRTSLASYARYWREAFRLPTMNPHTVAKQVEAYGIDLHRVGEALDAGRGVVLALPHSGNWDMAGVWLVQCHGTFTTVAERLKPESLYRRFINYRENLGFEVLPMSANKDTGFQALFELLCERLRSNRVVCLMAERDLTRTGVEVDFFGEPTRMPAGPAKLAIKTGAALLPVHCWFQGSGWGFSVHPALDCTSGDVGDVTQALADQFAQDIAANPTDWHMLQPQWLADLSDAKRAQLRPN
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