Gene ML0489
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Possible conserved lipoprotein |
| Comments | ML0489, len: 555 aa. Possible conserved lipoprotein precursor, possibly attached to the membrane by a lipid anchor and substrate-binding protein involved in transport, highly similar to YP85_MYCTU|Q50636|Rv2585c Possible conserved lipoprotein precursor from M. tuberculosis (557 aa), Fasta scores: E(): 4.7e-164, (78.9% identity in 546 aa overlap); and CAD94801|Mb2616c from M. bovis (557 aa). Also similar in part to various proteins, principally substrate-binding proteins, e.g. O87329|DCIAE DIPEPTIDE-BINDING PROTEIN from Corynebacterium glutamicum (Brevibacterium flavum) (502 aa), FASTA scores: E(): 4.4e-26, (29.224% identity in 438 aa overlap); Q8U840 ABC transporter, substrate binding protein from Agrobacterium tumefaciens (strain C58/ATCC 33970) (553 aa), fasta scores: E(): 2.5e-05, (24.726% identity in 457 aa overlap). Previously sequenced as YP85_MYCLE|Q49646 (426 aa), Fasta scores: E(): 0, (98.8% identity in 332 aa overlap). Contains a probable N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 593295 | 594962 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0489|ML0489
LRSGLFGVLRWTAVGLVATLVASLALTACSGSAAGEIVYVVDGALGTYNTNTIVGAASAGAQAFARTLIGFGYHGPDGQIVADHDFGTITVVGGVPLVLDYQIADNAVYSDGKQVTCDDLVLTWAAQSGRFPGFDAATQAGYRDIANIECLAGQKKSRVFFVPDRSVVDYEQLFAATSMMPSHVIADQLNIDVTEALLTHNATLVEQIARLWNTTWDLKPAVDLRRFPSSGPYKIESVLNGGAVVLVANDRWWGLKATTKRITVRPQEADIQDRVNNRSVDVVDVAVGSSGSLATPDNYARIDSPSAGIEQLIFAPQGLLAAAAARRALALCTPRDVVARDAGLSIANSRLSPATEDAIAAADGAREAGQFSKADPAAAHDALSGETLPVRIGYQGPNARLAATVGTIAKACAVAGISVSSVTLDSSTDPSGPQALRDGKIDVLLASTGGATGSGSSGSSSMDAYDLHTGNGNNLSGYANAQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTLPLYRQQRMLLMSKTMYAVTRNPTRWGAGWNMDRWALVR
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