Gene ML0535
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable carbamoyl-phosphate synthase small chain CarA (Carbamoyl- phosphate synthetase glutamine chain). SUBUNIT: COMPOSED OF TWO CHAINS; THE SMALL (OR GLUTAMINE) CHAIN PROMOTES THE HYDROLYSIS OF GLUTAMINE TO AMMONIA, WHICH IS USED BY THE LARGE (OR AMMONIA) CHAIN TO SYNTHESIZE CARBAMOYL PHOSPHATE. Belongs to the CarA family. |
| Comments | ML0535, len: 375 aa. Probable carA, Carbamoyl-phosphate synthase small chain (EC 6.3.5.5), highly similar to P71811|AL123456|Rv1383 carA, carbamoyl-phosphate synthase subunit from M. tuberculosis (376 aa), Fasta scores: E(): 0, (85.4% identity in 377 aa overlap); and CAD94279|Mb1418 from M. bovis (376 aa). Similar to many e.g. CARA_ECOLI|P00907 carA, carbamoyl-phosphate synthase subunit from Escherichia coli (382 aa), Fasta scores: E(): 0, (43.2% identity in 389 aa overlap). Contains Pfam match to entry PF00988 CPSase_sm_chain, Carbamoyl-phosphate synthase small chain, CPSase domain. Contains Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I. Contains PS00442 Glutamine amidotransferases class-I active site. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 648423 | 649550 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0535|carA
VSKALLVLEDGRVFTGMPFGAIGQTLGEAVFSTGMSGYQETLTDPSYHRQIVVATAPQIGNTGWNDQDGESRDDRIWVAGYAVRDPSPCASNWRATGTLEDELVRQRIVGIAGIDTRAVVRHLRRYGSMKAGVFSGKAMIEPLNIEALVQHVRTQQSMLGADLVGEASTLDAYVVEPKGKERFTVAALDLGIKTNTPRNFARRGIRSYVLPASATFNQIADIKPHGLFLSNGPGDPATADHVVALTREVLNAGIPLFGICFGNQILGRALGLSTYKMVFGHRGINIPVIDHATGRVAVTAQNHGFALEGEAGQSFDTPFGSAVVSHTCANDGVVEGVKLADGRAFSVQYHPEAAAGPHDAEYLFDSFVELMAAQR
Bibliography
No article yet recorded
