Gene ML0539 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePPE
Gene length1617 bp
IdentifierML0539
Location 654435 bp
Protein summary information
Molecular mass56126.2 Da
Isoelectric point4.35
Protein length539 amino acids
Structural information
PFAMPF00823
Orthologs
M. tuberculosis H37RvRv1387
M. lepromatosis Mx1-22AMLPM_0539
Cross-references
UniProtQ9CCQ9
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPPE-family protein
CommentsML0539, len: 538 aa. Member of the Mycobacteria PPE family, highly similar to P71657|AL123456|Rv1387 PPE20, PPE-family protein from M. tuberculosis (539 aa), Fasta scores: E(): 2.4e-119, (69.5% identity in 544 aa overlap); CAD94283|Mb1422 from M. bovis (539 aa). And similar to ML0411, ML1182, ML1828 and ML1991. Contains Pfam match to entry PF00823 PPE, PPE family.
Functional categoryPe/ppe
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS654435656051+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0539|PPE
MTNPWMAFPPEVQSAMLNFGAGVGPMLNSASYNLWLSAEYRWVASEVEALLREVRSGGWQGQAVEMFVGSCMPFLAWLMKAAADYMDVATQQEVVAAAYAAAVEAMPTQFELAANRVVRGVLMATNFFGVNTIPIALNEEEYVQMWVRAATTMATYSAISQSALAATPQATPPPLILKSNVLVDDVEKDSRHDGHSHGGHASAMDRVFADILRNVSGGRLVWDPLNGTLNGLDYDDYVYPGQPIWWLARGLEFFQDGEQFWELLFINPTAAFQFLLYIVVLDLPTHIVQLGTWLAEYPQLLLVALGGTIANLGAVTGLAGLSSGLSAGPSAAIPTVVPESAPIATVPAMLAGAGVAPAVVAPGASPSSAAPPASAASAAAAAPAPPGTGFGGFSPYLVDGRGPGVGFGSGRQSAYANKVSESVSDSAVAEAAAQASAREQARAWRRRSAAKERGYREEVITMNTGFDAAIPSPVDQTGSRVSDCGAGSFGFAGTVSKEAVVEVAGLTTLAGDDFGGGPTMPMVPGTWAPARESSDEGR
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