Gene ML0541
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable guanylate kinase Gmk (GMP kinase). |
| Comments | ML0541, len: 210 aa. Probable gmk, guanylate kinase (EC 2.7.4.8), highly similar to KGUA_MYCTU|P71659|Rv1389 gmk, putative guanylate kinase from M. tuberculosis (208 aa), Fasta scores: E(): 1.8e-62, (79.1% identity in 201 aa overlap). Similar to many e.g. Q9KXS0|KGUA_STRCO Guanylate kinase from Streptomyces coelicolor (197 aa), fasta scores: E(): 3e-31, (53.889% identity in 180 aa overlap). Contains Pfam match to entry PF00625 Guanylate_kin, Guanylate kinase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00856 Guanylate kinase signature. Belongs to the Guanylate kinase family. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 657267 | 657899 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0541|gmk
VPVSARGAPDAEHWAWSEQTDKGRVVVLSGPSAVGKSTVVRCLRERVSNLHFSVSATTREPRPDEMDGVDYHFVSPARFQQLIDQGALLEWAEIHGGMHRSGTLAEPVRVAAAAGFPVLIEVDLAGARAVKKAMPEAIAVFLAPPSWEDLEARLVGRGTETPEAIRRRLETARIELAAQDDFDEVVVNRRLESACAELVSLLVGAVSGSA
Bibliography
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