Gene ML0557c (P27) in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelprG
Gene length717 bp
IdentifierML0557c
Location 674680 bp
Protein summary information
Molecular mass24873.8 Da
Isoelectric point6.35
Protein length239 amino acids
Structural information
PFAMPF07161
Orthologs
M. tuberculosis H37RvRv1411c
M. lepromatosis Mx1-22AMLPM_0557
Cross-references
UniProtQ9CCP6
Gene OntologyPlasma membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable conserved lipoprotein LprG
CommentsML0557c, len: 238 aa. Probable lprG, conserved lipoprotein, highly similar to LPRG_MYCTU|P71679|Rv1411c lprG, putative lipoprotein from M. tuberculosis (234 aa), Fasta scores: E(): 0, (68.1% identity in 238 aa overlap) and similar to other M. tuberculosis lipoproteins e.g. Rv1270c, Rv1368, Rv2945c. Also similar to CAD94307|Mb1446c from M. bovis (236 aa) and to ML0136 from M. leprae. Contains probable N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Note that the Rv1410c-Rv1411c operon seems transcribed from two promoters in Mycobacterium bovis BCG (see Bigi et al., 2000).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS674680675396-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0557c|lprG
MQAPKHHRRLFAVLATLNTATAVIAGCSSGSNLSSGPLPDATTWVKQATDITKNVTSAHLVLSVNGKITGLPVKTLTGDLTTHPNTVASGNATITLDGADLNANFVVVDGELYATLTPSKWSDFGKASDIYDVASILNPDAGLANVLANFTGAKTEGRDSINGQSAVRISGNVSADAVNKIAPPFNATQPMPATVWIQETGDHQLAQIRIDNKSSGNSVQMTLSNWDEPVQVTKPQVS
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