Gene ML0563 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0563
Gene length897 bp
IdentifierML0563
Location 680811 bp
Protein summary information
Molecular mass32607.1 Da
Isoelectric point6.53
Protein length299 amino acids
Structural information
PFAMPF03668
Orthologs
M. tuberculosis H37RvRv1421
M. lepromatosis Mx1-22AMLPM_0563
Cross-references
UniProtQ9CCP0
Gene OntologyAtp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductConserved hypothetical protein
CommentsML0563, len: 298 aa. Conserved hypothetical protein, highly similar to YE21_MYCTU|P71690|Rv1421 conserved hypothetical protein from M. tuberculosis (301 aa), Fasta scores: E(): 0, (92.3% identity in 285 aa overlap); and CAD94317|Mb1456 from M. bovis (301 aa). Conserved in other bacteria e.g. Q9Z513|YJ52_STRCO Hypothetical UPF0042 protein from Streptomyces coelicolor (299 aa), fasta scores: E(): 2.2e-62, (54.698% identity in 298 aa overlap). Contains a match to Pfam entry PF03668; ATP_bind2;1.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS680811681707+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0563|ML0563
MSGNNHPGDASAEIDVVLVTGLSGAGRGTAAKVLEDLGWYVADNLPPQLITWMVDFGLAAGSRITQLAVVMDVRSRGFTGDLDSVRRELATRNIIPRVVFMEASDDMLVRRYEQNRRSHPLQGEQTLAEGIAAERRMLAPVRATADLIIDTSALSVPGLRESIERAFGGDASATTSVTVESFGFKYGLPMDADIVMDVRFLPNPHWVDELRSLTGQHSAVRDYVLGQPGAAEFLRTYRRLLSLVVDGYRREGKRYMTVAIGCTGGKHRSVAIAEALMGLLQSDLQLSVRVLHRDLGRE
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