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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH)
CommentsML0570, len: 339 aa. Probable gap, Glyceraldehyde 3-phosphate dehydrogenase (EC 1.2.1.12), highly similar to G3P_MYCTU|O06822|Rv1436 gap, Glyceraldehyde 3-phosphate dehydrogenase from M. tuberculosis (339 aa), Fasta scores: E(): 3.6e-124, (89.1% identity in 339 aa overlap); and CAD94332|Mb1471 from M. bovis (339 aa). Similar to many e.g. G3P_MYCAV|P94915 gap, glyceraldehyde 3-phosphate dehydrogenase from Mycobacterium avium (339 aa), Fasta scores: E(): 0, (87.9% identity in 339 aa overlap). Previously sequenced as G3P_MYCLE|P46713 (339 aa), Fasta scores: E(): 0, (99.7% identity in 339 aa overlap). Contains Pfam match to entry PF00044 gpdh, glyceraldehyde 3-phosphate dehydrogenases. Contains PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. Belongs to the Glyceraldehyde 3-phosphate dehydrogenase family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS694890695909+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0570|gap
VTVRVGINGFGRIGRNFYRALLAQQEHGIADVQVVAINDITDNSTLAYLLKFDSILGRLPHDVSLEEEDTIVVGSEKIKALAVREGPAALPWHAFGVDVVVESTGLFTNAAKAKGHLEAGAKKVIVSAPATDPDITIVFGVNDDKYDGSQNIISNASCTTNCLAPLAKVLHDQFGIVKGLMTTVHAYTQDQNLQDGPHSDLRRARAAALNVVPTSTGAAKAIGLVMPELKGKLDGYALRVPIPTGSVTDLTADLSKCVSVNEINAVFQDAAEGRLKGILKYVDAPIVSSDIVTDPHSSIFDSGLTKVIASQAKVVSWYDNEWGYSNRLVDLVGLVGKSL
      
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