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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable phosphoglycerate kinase Pgk
CommentsML0571, len: 416 aa. Probable pgk, Phosphoglycerate kinase (EC 2.7.2.3), highly similar to PGK_MYCTU|O06821|Rv1437 pgk, phosphoglycerate kinase from M. tuberculosis (412 aa), Fasta scores: E(): 2.7e-129, (80.6% identity in 412 aa overlap); and CAD94333|Mb1472 from M. bovis (412 aa). Similar to many e.g. PGK_CORGL|Q01655 pgk, phosphoglycerate kinase from Corynebacterium glutamicum (403 aa), Fasta scores: E(): 7.4e-94, (59.2% identity in 407 aa overlap). Previously sequenced as PGK_MYCLE|P46712 (416 aa), Fasta scores: E(): 0, (99.8% identity in 416 aa overlap). Contains Pfam match to entry PF00162 PGK, Phosphoglycerate kinases. Contains PS00111 Phosphoglycerate kinase signature. Belongs to the Phosphoglycerate kinase family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS695912697162+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0571|pgk
VRIPNLKDLLEEGVSGRCVLVRCDLNVPLGDDGAITDLGRVTASVPTLKALLEAGAKIVVAAHLGRPKNGPDPKLSLEPVAAALGEQLGQNVQLVCSTDRSPVGGDALACVERLTDGDLLLLQNIRFDPRETSKVDDERLALAKQLVELVGSAGAFVSDGFGVVHRRQASVYDVATLLPHYAGILVADEIRILEQLTSSAKRPYAVVLGGSKVSDKLGVIESLATKADSIVLGGGMCFTFLAAQGFSVGKSLLETEMIETCRSLLDTYADVLRLPMDIVVTEKFVADSPPQTVAADAIPDGLMGLDIGPESVKRFATLLSNASTIFWNGPMGVFEFPAYAAGTRGVAEAIVAVTGKGAFSVVGGGDSAAAMRALSLPEGSVSHLSTGGGASLEYLEGKTLPGIEVLGREQPRGGDS
      
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