Gene ML0579c (pgl)
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable 6-phosphogluconolactonase DevB (6PGL) |
| Comments | ML0579c, len: 247 aa. Possible devB (pgl), 6-phosphogluconolactonase (EC 3.1.1.31), highly similar to 6PGL_MYCTU|O06814|Rv1445c devB, 6-phosphogluconolactonase from M. tuberculosis (247 aa), Fasta scores: E(): 0, (72.8% identity in 246 aa overlap); and CAD96147|Mb1480c from M. bovis (247 aa). Similar to many e.g. Q9XAB7|6PGL_STRCO 6-phosphogluconolactonase from Streptomyces coelicolor (261 aa), fasta scores: E(): 5.5e-45, (51.639% identity in 244 aa overlap). Previously sequenced as 6PGL_MYCLE|Q49700 (247 aa), Fasta scores: E(): 0, (99.6% identity in 247 aa overlap). Contains Pfam match to entry PF01182 Glucosamine_iso, Glucosamine-6-phosphate isomerase. Belongs to the Glucosamine/Galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 703243 | 703986 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0579c|devB
VSASVEIFSDSKTMVGAAGKRLASTIQSAVAARERALIVLTGGSSGIGLLRDLATRGQQIDWSRVHLFWGDERYVPKDDDERNEKQARVALLDHIDIPPSQVHPMPAGDGEFGNDLEAAALAYEQLLAAYAAPGYPTPNFDVHLMGMGPEGHINSLFPNTVAVRETSRMVVGVRNSPKPPPERITLTLNAIQRSREVWLMVSGTAKADAVAAAMGGAPSASIPAAGAVGLETTLWLLDEEAAAKIPG
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