Gene ML0593
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Conserved hypothetical protein |
| Comments | ML0593, len: 869 aa. Conserved hypothetical protein, highly similar to YE61_MYCTU|O53152|Rv1461 Conserved hypothetical protein from M. tuberculosis (846 aa), Fasta scores: E(): 0, 54.3% identity in 920 aa overlap. N- and C-termini are similar to various bacterial hypothetical proteins e.g. Streptomyces coelicolor SCC22.07C, conserved hypothetical protein, TR:Q9XAD1 (EMBL:AL096839) (473 aa), Fasta scores: E(): 0, 45.5% identity in 853 aa overlap. Contains an intein from amino acids 202-587 inclusive. The intein is different to the one in the M. tuberculosis orthologue and at a different relative position. C-terminal half is similar to ML0594. Previously sequenced as SW:YE61_MYCLE (Q49689) (869 aa), Fasta scores: E(): 0, 99.9% identity in 869 aa overlap. Contains Pfam match to entry PF01458 UPF0051, Uncharacterized protein family (UPF0051). Contains PS00881 Protein splicing signature. |
| Functional category | Conserved hypotheticals |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 718689 | 721298 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0593|ML0593
MTRTSETTKSPAPELLTQQQAIDSLGKYGYGWADSDVAGASARRGLSEDVVRDISAKKDEPEWMLQARLKALRVFERKPMPRWGSNLDGIDFDNIKYFVRSTEKQAASWDELPEDIRNTYDRLGIPDAEKQRLVAGVAAQYESEVVYHQIRADLKDQGVVFLDTETGLREYPDIFKQYLGTVIPAGDNKFSALNTAVWSGGCLTADARINVKGKGLVSIADVQPGDEVFGVNIGCELERGKVLAKVASGTKPVYEMHVAGRALEATGNHQFLVARRVEEGKRTRWTAVWAPLEEIESGEPIAVARVLPDDSGTIFFSESELDIKNRTRQCLYFPCQNSVDLLWLLGLWLGDGHTAAPHKHMRQVAFSVPAGDPVHHTAIRVVSEQFGANVTVVNCGFIVSSKAFETWLAELGFSGDEKTKRLPAWIYSLPHEHQLALIGGLVDADGWTESSGATMSIAFASRELLEDVRQLAIGCGLYPDGALVERTRSATCRDGRIVTSTSWRLRIQGSLDRVGTRTPGKRGKPVSNKGRRQRYVAAAGLNFSSLSTDTVGFARLKSKTLVGEKPTYDIQVVGLENFVANGIVAHNSFIYVPPGVHVDIPLQAYFRINTENMGQFERTLIIADTGSYVHYVEGCTAPIYKSDSLHSAVVEIIVKPHARVRYTTIQNWSNNVYNLVTKRARVETGATMEWIDGNIGSKVTMKYPAVWMTGEHAKGEVLSVAFAGEGQHQDTGAKMLHLASNTSSNIVSKSVARGGGRTSYRGLVQVNKGAHGSRSSVKCDALLVDTISRSDTYPYVDIREDDVTMGHEATVSKVSENQLFYLMSRGLAEDEAMAMVVRGFVEPIAKELPMEYALELNRLIELQMEGAVG
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