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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable conserved ATP-binding protein ABC transporter
CommentsML0595, len: 260 aa. Probable conserved ATP-binding protein ABC transporter, highly similar to O53154|AL123456|Rv1463 conserved ATP-binding protein ABC transporter from M. tuberculosis (266 aa), Fasta scores: E(): 1.7e-81, (85.8% identity in 267 aa overlap); and CAD96165 from M. bovis (266 aa). Similar to many members of the ABC transporter family e.g. Q8NQ77 ABC-type transporter, ATPase component from Corynebacterium glutamicum (Brevibacterium flavum) (252 aa), fasta scores: E(): 3.1e-61, (65.873% identity in 252 aa overlap); and members found in chloroplast genomes e.g. ABCX_CYAPA|P48255 ycf16, probable ATP-dependent transporter from Cyanophora paradoxa (259 aa), Fasta scores: (54.2% identity in 227 aa overlap). Previously sequenced as Q49693|U00013 (260 aa), Fasta scores: E(): 0, (100.0% identity in 260 aa overlap). Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the ATP-binding transport protein family (ABC transporters).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS722470723252+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0595|ML0595
MTTLIVKDLYVSVEHPNAAESECQIPILNGVDLTVKSGETHALMGPNGSGKSTLSYAIMGHPKYRVISGAITLDGADVLTMSVDERARAGLFLAMQYPVEVPGVSVSNFLRSAATVIRGEPPKLRHWVKEVKAAMGALEIDPVFAERSVNEGFSGGEKKRHEILQLELLKPKIAILDETDSGLDVDALRVVSDGVNRYADSEHGGILLITHYTRILRYIRPEFVHVFVGGRIVESGGSELADELEQNGYVRFSQPAATGV
      
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