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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable cysteine desulfurase Csd
CommentsML0596, len: 418 aa. Probable csd, cysteine desulfurase (EC 4.4.1.- ), highly similar to O53155|AL123456|Rv1464 Probable csd, cysteine desulfurase from M. tuberculosis (417 aa), Fasta scores: E(): 0, (85.4% identity in 417 aa overlap); and CAD96166|Mb1499 from M. bovis (417 aa). Similar to others e.g. Q9XAD5|CSD_STRCO Probable cysteine desulfurase from streptomyces coelicolor (418 aa), fasta scores: E(): 2.5e-88, (53.382% identity in 414 aa overlap). Previously sequenced as Q49690|U00013 (418 aa), Fasta scores: E(): 0, (100.0% identity in 418 aa overlap). And similar to part of ML0842 and to ML0117 and ML1708. Contains Pfam match to entry PF00266 aminotran_5, Aminotransferases class-V. Contains PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. Belongs to the class-V of pyridoxal-phosphate-dependent aminotransferases. Csd subfamily.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS723255724511+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0596|csd
MTISLTPLDLSAIRADFPILKRVMRGGNQLAYLDSGATSQRPVQVLDAEREFLVTSNGAVHRGAHQLMEEATDAYERGRVDIAAFIGAAADELVFTKNATESLNLVSYVFGDNRFEGTSGDGGDVIVTTELEHHANLIPWQELARRIGATLRWYGVTDDGQIDLDSLQLDERVKVVAFSHHSNVTGAVAPVRELVARAKEVGALTVLDACQSVPHQPVDLHGLGVDFAAFSGHKMLGPNGIGVLYARRELLSVMPPFLTGGSMIETVTMESTTYAPAPQRFEAGTPMTSQVVGLAAAARYLDAIGMKAVEAHERELVAAAVEGLSRIDGVRIIGPKSMENRGSPVSFVVDGVHAHDIGQVLDDDGVAVRVGHHCALPLHRRFALAATARASFAVYNTVDEVDRLVAGVLRALDFFGRE
      
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