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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable GTP-binding protein Era
CommentsML0631, len: 302 aa. Probable era, GTP-binding protein, highly similar to ERA_MYCTU|O05834|Rv2364c era, GTP-binding protein from M. tuberculosis (300 aa), Fasta scores: E(): 5.9e-95, (81.4% identity in 301 aa overlap); and CAD97246|Mb2385c (300 aa) from M. bovis. Similar to many bacterial era-homologues and to ERA_ECOLI|P06616 era, GTP-binding protein from Escherichia coli (301 aa), Fasta scores: E(): 3.3e-30, (34.3% identity in 297 aa overlap). Previously sequenced as ERA_MYCLE|Q49768 (302 aa), Fasta scores: E(): 0, (99.7% identity in 302 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). CONTAINS 1 KH TYPE-2 DOMAIN. BELONGS TO THE ERA/TRME FAMILY OF GTP-BINDING PROTEINS, ERA SUBFAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS763477764385+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0631|era
VDMAEFRSGFVCLIGRPNTGKSTLTNALVGTKVAITSMKPQTTRHTIRGIVHREGNFQIVLVDTPGLHRPRTLLGKRLNDLVRDTYTEVDLIGLCIPADEATGPGDRWIVNQIRSVAPKTILVVIVTKIDKVPKDRLSAQLVAVSDLVADSAEIVPVSAVTGEQVDVLIDVLAAALPPGPAYYSAGELTDEPEELLMAELIREAVLEGVHDELPHSLAVVIDEVSPRAGRGDLIDVHAVLYVERPSQKGIVIGKSGARLREVGIAARRQIEKLLGTNIYLDLHVNVAKNWQRNPKQLGRLGF
      
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